LOCUS       NZ_CP031719             5596 bp    DNA     circular CON 05-JAN-2024
DEFINITION  Klebsiella pneumoniae strain SCKP020003 plasmid p3_020003, complete
            sequence.
ACCESSION   NZ_CP031719
VERSION     NZ_CP031719.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN06909161
            Assembly: GCF_002164855.2
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 5596)
  AUTHORS   Liu,L., Long,H., Feng,Y. and Zong,Z.
  TITLE     The complete genome of Klebsiella pneumoniae strain SCKP020003
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5596)
  AUTHORS   Liu,L., Long,H., Feng,Y. and Zong,Z.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2018) Center of Infectious Diseases, West China
            Hospital, Sichuan University, Guoxuexiang 37, Chengdu, Sichuan
            610041, China
REFERENCE   3  (bases 1 to 5596)
  AUTHORS   Liu,L., Feng,Y. and Zong,Z.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-MAY-2017) Center of Infectious Diseases, West China
            Hospital, Sichuan University, Guoxuexiang 37, Chengdu, Sichuan
            610041, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.6
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200.0x
            Sequencing Technology             :: Illumina HiSeq; MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/04/2024 21:03:44
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,604
            CDSs (total)                      :: 5,484
            Genes (coding)                    :: 5,357
            CDSs (with protein)               :: 5,357
            Genes (RNA)                       :: 120
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 85
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 48 of 127
            Pseudo Genes (incomplete)         :: 80 of 127
            Pseudo Genes (internal stop)      :: 15 of 127
            Pseudo Genes (multiple problems)  :: 16 of 127
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP031719.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..5596
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="SCKP020003"
                     /host="Homo sapiens"
                     /db_xref="taxon:573"
                     /plasmid="p3_020003"
                     /geo_loc_name="China: Yibin, Sichuan"
                     /collection_date="2016-09"
     gene            join(5364..5596,1..313)
                     /locus_tag="CAY64_RS00205"
                     /old_locus_tag="CAY64_00205"
     CDS             join(5364..5596,1..313)
                     /locus_tag="CAY64_RS00205"
                     /old_locus_tag="CAY64_00205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004197758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_023317533.1"
                     /translation="MFFKRYLTEKEIYKAALPIVRLQGRVNTSLRFLSKYSDVNKNGLI
                     ALHLNLLHFISYNIHGVESLKITQAGINKAVQQSPHADEIKNIAQAIGRKGPEYIEGLI
                     RNPWGKKNDNPLIFIMSIEESIKETLNSGYMLYRVAPITEGEAAAFMDVLKQLLLFEDN
                     FRLFGRDLVYKIEKLKIR"
                     /name="hypothetical protein"
     gene            379..729
                     /locus_tag="CAY64_RS00210"
                     /old_locus_tag="CAY64_00210"
     CDS             379..729
                     /locus_tag="CAY64_RS00210"
                     /old_locus_tag="CAY64_00210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004197756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004197756.1"
                     /translation="MYWLIAFLAFIFPGRSFADGYTAYYRCNGTQEASLTVKDNKLSMV
                     VGLSKFNRQLDTYRFKEKGIEVVMQRAASDDNSEAIMSFIMPDVNNMTLLVKNNGYIIV
                     KTTCWLTKTDKQ"
                     /name="hypothetical protein"
     gene            complement(799..1065)
                     /locus_tag="CAY64_RS00215"
                     /old_locus_tag="CAY64_00215"
     CDS             complement(799..1065)
                     /locus_tag="CAY64_RS00215"
                     /old_locus_tag="CAY64_00215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262326.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_004197762.1"
                     /translation="MVWTINYSDRALKSLRKMDKQNARRIVDFMSLRIAVAADPRQSGK
                     PLKGELGEFWRYRVGDYRVLCEIRDDELVILAATIGHRREVYD"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(1049..1273)
                     /locus_tag="CAY64_RS00220"
                     /old_locus_tag="CAY64_00220"
     CDS             complement(1049..1273)
                     /locus_tag="CAY64_RS00220"
                     /old_locus_tag="CAY64_00220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6290 family protein"
                     /protein_id="WP_000879771.1"
                     /translation="MLAIRLSDEIESRLDSLAKQTGRTKTFYAREAILAHLEDLEDYYL
                     SAETAARVRRGDEAVHSSEDVRKSLGLDD"
                     /name="DUF6290 family protein"
     gene            complement(1940..2152)
                     /locus_tag="CAY64_RS00225"
                     /old_locus_tag="CAY64_00225"
     CDS             complement(1940..2152)
                     /locus_tag="CAY64_RS00225"
                     /old_locus_tag="CAY64_00225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeD family mobilization/exclusion protein"
                     /protein_id="WP_021527181.1"
                     /translation="MTELEKQLLSALEQLQQDYSKRLDEWESAFGEWRKMSGLMQRENA
                     ALSERVTRLSQQVERLSGQLQRLSR"
                     /name="MbeD family mobilization/exclusion protein"
     gene            complement(2159..2668)
                     /locus_tag="CAY64_RS00230"
                     /old_locus_tag="CAY64_00230"
     CDS             complement(2159..2668)
                     /locus_tag="CAY64_RS00230"
                     /old_locus_tag="CAY64_00230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020325392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeB family mobilization protein"
                     /protein_id="WP_032433972.1"
                     /translation="MNSLLTLAKDLEQKSKAQQQSTGEMLKAAFSEHEKSVRAELSESG
                     KRISAAIRAHEQGMSAAMQSNRLSVMRMVGRTWLTITMVSGLLFASLSGVLWYQGSLIA
                     SNLAEIDRQNAALSKLNAKTWGVTYLEDSNGRFLVLPKGTAVDRTQSWTVGNGRSKQNA
                     LRLVKE"
                     /name="MbeB family mobilization protein"
     gene            complement(<2703..3407)
                     /locus_tag="CAY64_RS30825"
                     /old_locus_tag="CAY64_00235"
                     /pseudo=""
     CDS             complement(<2703..3407)
                     /locus_tag="CAY64_RS30825"
                     /old_locus_tag="CAY64_00235"
                     /inference="COORDINATES: protein motif:HMM:NF015397.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /name="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            complement(3346..3690)
                     /locus_tag="CAY64_RS00240"
                     /old_locus_tag="CAY64_00240"
     CDS             complement(3346..3690)
                     /locus_tag="CAY64_RS00240"
                     /old_locus_tag="CAY64_00240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006122514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="WP_062955149.1"
                     /translation="MAVKRTRFLGIRVTDGEYQQLLERCNGRQLAVWMRETCLDTRPAR
                     SLRLPSIDPVLLRQLAGMGNNLNQIARKINGGQWSGADRVQVVAALMAIDAELERLRHA
                     VLEKGADDDR"
                     /name="MobC family plasmid mobilization relaxosome protein"
     gene            complement(3680..3856)
                     /locus_tag="CAY64_RS29155"
     CDS             complement(3680..3856)
                     /locus_tag="CAY64_RS29155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004197757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004197757.1"
                     /translation="MQKPKKKPLVVKKRSWHPAVMANLMRQAQEEDYRREQMAELERSA
                     RSHFADIGGEDGG"
                     /name="hypothetical protein"
     gene            4496..4654
                     /locus_tag="CAY64_RS30830"
     CDS             4496..4654
                     /locus_tag="CAY64_RS30830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_071596352.1"
                     /translation="MHEPPVQPDCCALSGNYHLESNPDGHAKTPLAAAIGNWIYTREIL
                     RGLEVGA"
                     /name="replication initiation protein"
     gene            5012..5338
                     /locus_tag="CAY64_RS00250"
                     /old_locus_tag="CAY64_00250"
     CDS             5012..5338
                     /locus_tag="CAY64_RS00250"
                     /old_locus_tag="CAY64_00250"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_050516389.1"
                     /translation="MRERTNIMLDIGLKQSLQRLSNKTKMSLSDLINQRLSGSLSVEER
                     IGEKPEWMRNLDPYLANHFSNIELPLPSPLKEYQEKMDEIDSIINDMMVLKEYFRAKFY
                     DEIK"
                     /name="hypothetical protein"
     Typing          complement(3943..4019)
                     /name="MOBP"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="91.25"
                     /coverage="98.0"
                     /evalue="1.04e-21"
     Typing          4208..4605
                     /name="rep_cluster_2370"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="89.526"
                     /coverage="91.0"
                     /evalue="3.03e-139"
     Typing          complement(1825..3356)
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="99.804"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 aagccctcac gcagatgaaa taaaaaatat tgcgcaggca ataggacgca aaggacctga
       61 gtacatcgaa ggattaatta gaaacccatg ggggaagaaa aatgataatc cactaatatt
      121 tataatgagc attgaagaaa gtataaaaga aacccttaac tcaggttata tgttatatag
      181 agtagctccc ataactgagg gtgaagcagc tgctttcatg gatgttctta aacaattatt
      241 attatttgag gataattttc gcctttttgg tagagacttg gtttataaaa tagaaaaatt
      301 aaaaatcaga taacaaagta tggtgaacga aaaatgaaag agaggatagt gaaatgtgta
      361 ataccaagat tctcaactat gtattggtta attgcgttcc tagcatttat attccccggt
      421 cgatcttttg ctgacggtta caccgcttac taccgatgta atggtactca ggaagcatct
      481 cttactgtta aagataacaa actaagtatg gttgtaggtc tttctaagtt taataggcaa
      541 ctggatactt atagattcaa agaaaaggga atcgaagtag taatgcagag agctgcttct
      601 gatgataact ctgaggccat aatgtctttt attatgcctg acgttaacaa tatgacctta
      661 ttagttaaaa ataacggcta cattatcgtt aagacaacct gctggttaac taaaaccgac
      721 aaacagtaga acacgtagtt agtcgagtat ttaccataat acctgttgtc ggcatcaaaa
      781 aagcccgcat agcgggcttc agtcgtaaac ttcgcggcga tgtccaatcg tggcggcaag
      841 gataacaagc tcgtcatctc ggatctcaca cagaacgcga taatctccca cccgatagcg
      901 ccagaactcg cccagctcac ctttgagcgg cttccctgac tggcgaggat cggcagcaac
      961 tgcaatgcgt aaactcataa aatccacaat ccgtcgtgcg ttctgtttgt ccatcttgcg
     1021 taacgatttg agcgcccgat cggaatagtt aatcgtccag accaagtgac ttcctcacgt
     1081 cttcagacga atgcactgct tcatcaccac ggcgaacgcg tgcagcagtt tctgctgaaa
     1141 gataataatc ctccaggtct tccagatgcg ccagtattgc ttcccgcgca taaaacgtct
     1201 ttgttctgcc ggtttgcttc gccagcgagt ccagacggga ctcaatctca tcagataacc
     1261 ggatagcaag catataaacc tcccgaacac catttgctat acatgtatat caacagtacc
     1321 acaatcaacc taaaagaaca aaaaataatc ttgttagccc ctcttgataa tccgtaacgc
     1381 ggtcaatata tctagcttga gggctttcct cttaactatt gaaaggataa cgattatggg
     1441 tcttaagccg ggtccgaaac gaattgccga ttcaacaggg gaacctgata aacgccagcg
     1501 tgacaataaa aaaacgccgg gaaatactga caaattgaaa cccagcaaat cttcaaaaaa
     1561 ataagtcagt agttaaaagc cctccggggc ttttttgtat ctgccgttca cgctgattaa
     1621 acataacacc cgttgcccgc accgccccgg acgggttcgc cgcgaacggg gtggcagtca
     1681 ggtaaaaccg gcaacaaacc acccgataaa ccgccccgtt cgcgacagat aaattttacc
     1741 tggctgcata gccatgcagc caggtgaatg acatccggtt tcagcgtaaa tgcccgatga
     1801 gaaccctgtt ttcctgcatt tcagcccagc gacggaccgt catagcttcg ctgccgggaa
     1861 cgcgcttccg tcagttcctt ttcgtgctgc cgttgctcgt gcgcccgttc tgcggccacg
     1921 gccatctcat gacgctgcac taccggctca aacgctgcag ttgcccgctc aagcgttcca
     1981 cctgctgact caagcgcgtc acgcgctcgc tcagcgccgc gttctcccgt tgcataagcc
     2041 ctgacatttt ccgccattcc ccgaaggcgc tctcccactc gtccagcctt ttcgagtagt
     2101 cctgctgtag ctgctctaat gcgctcagca actgtttttc cagctcggtc atcggcactt
     2161 actccttcac cagtctcagc gcgttctgct tcgaccgccc gttcccgacc gtccagctct
     2221 gcgtcctgtc tacggccgtc cccttcggca gcaccagaaa acgtccgttg ctgtcttcca
     2281 ggtacgtcac gccccaggtc ttcgcgttca gcttcgacag cgctgcgttc tgccggtcga
     2341 tttcggccag atttgacgct atcaagctcc cctgatacca caacaccccg ctcaggctgg
     2401 cgaacagcag tcctgacacc atcgtgatgg tcagccatgt ccgcccgacc atacgcatca
     2461 cgctcaggcg gttcgactgc atggccgcgc tcataccctg ctcgtgggcg cggatggcgg
     2521 cgctgattct cttcccgctt tcgctcagtt ccgctctgac agacttctcg tgctcgctga
     2581 atgcggcttt cagcatttcg ccggtactct gctgctgcgc tttcgatttc tgctctaagt
     2641 ccttcgccag cgttaaaaga ctgttcatag atggctccct taagtcggat gtttcgccct
     2701 ccgtccgggt cggcaatgct gatgctgctc tttgtggtgc gcacgacctc aaaacctgcg
     2761 ctttccagcg cctcagtgac gtcctgacgc gttttaagct cccctgacga ggcgagggcc
     2821 agtaagcccc gcgtaatagc ctctgcggct tcctgcttcg ttttgggtaa cgaagatggc
     2881 gtcaccagcg cgcgccggtt ctccggtgcg ttcgggtcgt gcagccccag tcgcccgttc
     2941 accacggtct gccacgcatc gatgcgcgga cggtctgccc ggtcgtagta cggctggaga
     3001 cgcctgccgg tcagcagttc cgtgttcggt accagaaaat tcagttccag ccgccccttg
     3061 tcccggtgtt caacccacag cacgctgtac tggtctttat cgagtccggg catcagaacc
     3121 cgctcgaagc tcgccatcag cttttcacgc tggccgggcg gtaaatcctg ttcagcaaaa
     3181 gacaggacgc cggaggtgta ctttttggcg tagggcgagg cgtcgataag ctcccggacc
     3241 tcctccggct ttccctgcag gacgatggcc ccgtcgcgct ggcggtcttt ccccagcaga
     3301 taatccaccg gcccggcacc gccgcctcgc cctcgcggat gaaacttaac gatcatcgtc
     3361 tgcccccttt tccagcacgg catgccgcag ccgctcgagt tcggcatcaa tggccatcag
     3421 cgcggccacc acctgaaccc ggtcagcgcc tgaccactgg ccgccgttaa ttttccgggc
     3481 gatctggttg aggttgttcc ccatcccggc aagctggcgc agcaaaaccg gatcgatgga
     3541 cggcagccgc aacgaccgcg ccgggcgcgt atcgagacag gtttcccgca tccacaccgc
     3601 cagttgcctt ccattgcagc gctccagcag ctgctggtac tccccatcgg tcacccggat
     3661 acctaaaaaa cgggtacgct taaccgccat cctctcctcc gatatccgca aaatgtgacc
     3721 gggctgaacg ctcaagctct gccatctgct cccggcggta atcttcctcc tgtgcctgac
     3781 gcatcagatt tgccatcact gccggatgcc aggatctttt ttttacgacg agcggcttct
     3841 tcttcggctt ctgcattatc cctccttcgc aaacgccgga cggcacggaa aagttttccg
     3901 ggtcgctccg gcgttggaca agcgccagcg cgtcagtggt gttagcgggt ttcggggcgc
     3961 agccctgaac cagtcacagc gtttacgctg tgtatactgg cttactatgt tggcatgaga
     4021 gcacgattca tgaaagtgcc tcatgtggca ggtgtgatat gtggctcagg agcgtccgca
     4081 ataccatgca cggacagatg aaatgacgcc tcctcgctca ctcggtagct gcgctcctgc
     4141 cgttcggctg cggcgggcgt gaccgactca cggataacgg gataaagcaa aggcgctcaa
     4201 atcagaaagg gccggagaaa aggatgcggc gttgccgttt ttccataggc tccgcctccc
     4261 ctgacgagca tcacagaaat ggacgctcaa gtcagaggag gacgaaaccc gacaggactt
     4321 aaagatgccg gtgatttctc tccggcggct ccctcgtgcg ctctcctgtt ccgaccctgc
     4381 cgtttaccgg atacctgttc cgcctttttc cctttcggga agcgtggcgc tttctcatag
     4441 ctcacgctgc tggtatctcg gctcggttta ggtcgttcgc tccaagctgg gctgtatgca
     4501 cgaacccccc gttcagcccg actgctgcgc cctttccggt aactatcatc ttgagtccaa
     4561 cccggacgga cacgcaaaaa cgccactggc agcagccatt ggtaactgga tatatacgag
     4621 agagatattg agaggtcttg aagtgggtgc ctaactgcgg ctacactgaa agaacagttt
     4681 tggtatctgc ggtctcgtat acccagttac ccggttaagc agttccccaa ctgacttaac
     4741 cttcgatcaa accgcctccc caggcggttt tttcgtttac agtgcaagag attacgcgca
     4801 gaaaaaaagg atctcaagaa gatcctttaa atgatcgtca gttctgttat ccccggagct
     4861 ccatccatcc cacggaaaaa cacccgccac tgatgccctc agcgcactgc acatcatgta
     4921 caaaccactc cctccctcct tttttattgc gtttcttaat gcgcaatggt agctttgtgc
     4981 gcaacaaaaa acgcaatagc aagggggggt aatgagagaa agaacaaata tcatgctaga
     5041 tataggatta aagcaatcct tacaacggct ttcgaataaa accaaaatga gtctaagtga
     5101 tcttattaac cagagattat caggttcact ttcagttgaa gaacgcattg gcgaaaagcc
     5161 tgaatggatg agaaaccttg atccctatct cgccaatcac ttttcaaata ttgagttacc
     5221 gctcccttca ccattaaaag aataccaaga aaaaatggat gagatagatt caattattaa
     5281 tgacatgatg gttctaaagg aatatttcag agctaagttt tacgacgaaa taaaataggc
     5341 acgctatacg gaggcggaga attatgtttt ttaaacggta tttaacggag aaggaaatat
     5401 acaaggcagc actcccaatt gttaggcttc aagggagagt taacacttca ttacgttttt
     5461 tatccaaata ctcagatgta aacaaaaatg gattaattgc attgcatctt aatttattac
     5521 attttatctc atacaacata cacggtgtag agtctctgaa aatcactcaa gcaggcataa
     5581 acaaagctgt acaaca
//
