LOCUS       NZ_CP031717            18218 bp    DNA     circular CON 05-JAN-2024
DEFINITION  Klebsiella pneumoniae strain SCKP020003 plasmid p1_020003, complete
            sequence.
ACCESSION   NZ_CP031717
VERSION     NZ_CP031717.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN06909161
            Assembly: GCF_002164855.2
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 18218)
  AUTHORS   Liu,L., Long,H., Feng,Y. and Zong,Z.
  TITLE     The complete genome of Klebsiella pneumoniae strain SCKP020003
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 18218)
  AUTHORS   Liu,L., Long,H., Feng,Y. and Zong,Z.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2018) Center of Infectious Diseases, West China
            Hospital, Sichuan University, Guoxuexiang 37, Chengdu, Sichuan
            610041, China
REFERENCE   3  (bases 1 to 18218)
  AUTHORS   Liu,L., Feng,Y. and Zong,Z.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-MAY-2017) Center of Infectious Diseases, West China
            Hospital, Sichuan University, Guoxuexiang 37, Chengdu, Sichuan
            610041, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.6
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200.0x
            Sequencing Technology             :: Illumina HiSeq; MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/04/2024 21:03:44
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,604
            CDSs (total)                      :: 5,484
            Genes (coding)                    :: 5,357
            CDSs (with protein)               :: 5,357
            Genes (RNA)                       :: 120
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 85
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 48 of 127
            Pseudo Genes (incomplete)         :: 80 of 127
            Pseudo Genes (internal stop)      :: 15 of 127
            Pseudo Genes (multiple problems)  :: 16 of 127
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP031717.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..18218
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="SCKP020003"
                     /host="Homo sapiens"
                     /db_xref="taxon:573"
                     /plasmid="p1_020003"
                     /geo_loc_name="China: Yibin, Sichuan"
                     /collection_date="2016-09"
     gene            71..886
                     /locus_tag="CAY64_RS00005"
                     /old_locus_tag="CAY64_00005"
     CDS             71..886
                     /locus_tag="CAY64_RS00005"
                     /old_locus_tag="CAY64_00005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032492145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(3')-Ia"
                     /protein_id="WP_000018329.1"
                     /translation="MSHIQRETSCSRPRLNSNMDADLYGYKWARDNVGQSGATIYRLYG
                     KPDAPELFLKHGKGSVANDVTDEMVRLNWLTEFMPLPTIKHFIRTPDDAWLLTTAIPGK
                     TAFQVLEEYPDSGENIVDALAVFLRRLHSIPVCNCPFNSDRVFRLAQAQSRMNNGLVDA
                     SDFDDERNGWPVEQVWKEMHKLLPFSPDSVVTHGDFSLDNLIFDEGKLIGCIDVGRVGI
                     ADRYQDLAILWNCLGEFSPSLQKRLFQKYGIDNPDMNKLQFHLMLDEFF"
                     /name="aminoglycoside O-phosphotransferase APH(3')-Ia"
     gene            complement(1076..1744)
                     /locus_tag="CAY64_RS00010"
                     /old_locus_tag="CAY64_00010"
     CDS             complement(1076..1744)
                     /locus_tag="CAY64_RS00010"
                     /old_locus_tag="CAY64_00010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="WP_044117068.1"
                     /translation="MILWAVRWYCKYGISYRELQEMLAERGVNVDHSTIYRWVQRYAPE
                     MEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDFYLSSRRNSKAAY
                     RFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHRQIKYRNNVIECD
                     HGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPLGEMRLVSRVFEM
                     "
                     /name="IS6 family transposase"
     gene            complement(2036..3040)
                     /locus_tag="CAY64_RS00015"
                     /old_locus_tag="CAY64_00015"
     CDS             complement(2036..3040)
                     /locus_tag="CAY64_RS00015"
                     /old_locus_tag="CAY64_00015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229637.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110-like element IS5075 family transposase"
                     /protein_id="WP_000427619.1"
                     /translation="MENIALIGIDLGKNSFHIHCQDHRGKAVYRKKFTRPKLIEFLATC
                     PATTIAMEACGGSHFMARKLEELGHFPKLISPQFVRPFVKSNKNDFVDAEAICEAASRP
                     SMRFVQPRTESQQAMRALHRVRESLVQDKVKTTNQMHAFLLEFGISVPRGAAVISRLST
                     LLEDSSLPLYLSQLLLKLQQHYHYLVEQIKDLESQLKRKLDEDEVGQRLLSIPCVGTLT
                     ASTISTEIGDGKQYASSRDFAAATGLVPRQYSTGGRTTLLGISKRGNKKIRTLLVQCAR
                     VFIQKLEHQSGKLADWVRELLCRKSNFVVTCALANKLARIAWALTARQQTYEA"
                     /name="IS110-like element IS5075 family transposase"
     gene            3268..4473
                     /gene="chrA"
                     /locus_tag="CAY64_RS00020"
                     /old_locus_tag="CAY64_00020"
     CDS             3268..4473
                     /gene="chrA"
                     /locus_tag="CAY64_RS00020"
                     /old_locus_tag="CAY64_00020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004896675.1"
                     /GO_function="GO:0015109 - chromate transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0015703 - chromate transport [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate efflux transporter"
                     /protein_id="WP_000184001.1"
                     /translation="MTNNPTDDSRPWSVFLIFLRLGLTSFGGPIAHLGYFRAEFVTRRR
                     WLSERSYADLVALCQFLPGPASSQVGIAVGLSRAGYSGALAAWAGFTLPSAIALILFAL
                     GISSYGDYVSQGALHGLKVVAVAVVAQAVWGMARNLCTDGLRVTIMAIATCVVLLVPSA
                     WGQVGVIAIAGIAGRLLFKPAKVVEHDPLPITVSHRAGVLWLSLFFVLLIGLPVLAELM
                     PSQTMAMVDSFYRVGSLVFGGGHVVLPLLQAEVVPSGWVNNESFLAGYGAAQAVPGPLF
                     TFAAFLGASMNTAPSGWIGGIVCLLAIFAPSFLLVVGSMPFWERLRRNTGIQAALAGIN
                     AAVVGLLLAALYQPVWTSAIFQPQDFGLALVALVALMFWKLPPWLVVLGSGAAGWLLSV
                     AL"
                     /name="chrA"
     gene            4484..4789
                     /locus_tag="CAY64_RS00025"
                     /old_locus_tag="CAY64_00025"
     CDS             4484..4789
                     /locus_tag="CAY64_RS00025"
                     /old_locus_tag="CAY64_00025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000130000.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="WP_000130000.1"
                     /translation="MTDKDLYGGLIRLHILHHAAEEPVFGLGIIEELRRHGYEMSAGTV
                     YPMLHGLEKKGYLTSRHERTGRRERRVYDITEQGRTALADAKTKVKELFGELVEGG"
                     /name="PadR family transcriptional regulator"
     gene            <4833..4898
                     /locus_tag="CAY64_RS29140"
                     /pseudo=""
     CDS             <4833..4898
                     /locus_tag="CAY64_RS29140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229646.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /name="EAL domain-containing protein"
     gene            5016..5780
                     /locus_tag="CAY64_RS00035"
                     /old_locus_tag="CAY64_00035"
     CDS             5016..5780
                     /locus_tag="CAY64_RS00035"
                     /old_locus_tag="CAY64_00035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001389365.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS6100 family transposase"
                     /protein_id="WP_001389365.1"
                     /translation="MTDFKWRHFQGDVILWAVRWYCRYPISYRDLEEMLAERGISVDHT
                     TIYRWVQCYAPEMEKRLRWFWRRGFDPSWRLDETYVKVRGKWTYLYRAVDKRGDTIDFY
                     LSPTRSAKAAKRFLGKALRGLKHWEKPATLNTDKAPSYGAAITELKREGKLDRETAHRQ
                     VKYLNNVIEADHGKLKILIKPVRGFKSIPTAYATIKGFEVMRALRKGQARPWCLQPGIR
                     GEVRLVERAFGIGPSALTEAMGMLNHHFAAAA"
                     /name="IS6-like element IS6100 family transposase"
     gene            complement(6273..6857)
                     /gene="mphR(A)"
                     /locus_tag="CAY64_RS00050"
                     /old_locus_tag="CAY64_00050"
     CDS             complement(6273..6857)
                     /gene="mphR(A)"
                     /locus_tag="CAY64_RS00050"
                     /old_locus_tag="CAY64_00050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001137892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide-binding transcriptional repressor
                     MphR(A)"
                     /protein_id="WP_001137892.1"
                     /translation="MPRPKLKSDDEVLEAATVVLKRCGPIEFTLSGVAKEVGLSRAALI
                     QRFTNRDTLLVRMMERGVEQVRHYLNAIPIGAGPQGLWEFLQVLVRSMNTRNDFSVNYL
                     ISWYELQVPELRTLAIQRNRAVVEGIRKRLPPGAPAAAELLLHSVIAGATMQWAVDPDG
                     ELADHVLAQIAAILCLMFPEHDDFQLLQAHA"
                     /name="mphR(A)"
     gene            complement(6857..8095)
                     /gene="mrx(A)"
                     /locus_tag="CAY64_RS00055"
                     /old_locus_tag="CAY64_00055"
                     /gene_synonym="mrx"
     CDS             complement(6857..8095)
                     /gene="mrx(A)"
                     /locus_tag="CAY64_RS00055"
                     /old_locus_tag="CAY64_00055"
                     /gene_synonym="mrx"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000004159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide resistance MFS transporter Mrx(A)"
                     /protein_id="WP_000004159.1"
                     /translation="MSERRYSPLATLFAATFLFRIGNAVAALALPWFVLSHTKSAAWAG
                     ATAASSVIATIIGAWVGGGLVDRFGRAPVALISGVVGGVAMASIPLLDAVGALSNTGLI
                     ACVVLGAAFDAPGMAAQDSELPKLGHVAGLSVERVSSLKAVIGNVAILGGPALGGAAIG
                     LLGAAPTLGLTAFCSVLAGLLGAWVLPARAARTMTTTATLSMRAGVAFLWSEPLLRPLF
                     GIVMIFVGIVGANGSVIMPALFVDAGRQVAELGLFSSMMGAGGLLGIAIHASVGARISA
                     QNWLAVAFCGSAVGSLLLSQLPGVPVLMLLGALVGLLTGSVSPILNAAIYNRTPPELLG
                     RVLGTVSAVMLSASPMVMLAAGAFVDLAGPLPGLVVSAVFAGLVALLSLRLQFATMAAA
                     ATASAPTHTEGEH"
                     /name="mrx(A)"
     gene            complement(8092..8997)
                     /locus_tag="CAY64_RS00060"
                     /old_locus_tag="CAY64_00060"
     CDS             complement(8092..8997)
                     /locus_tag="CAY64_RS00060"
                     /old_locus_tag="CAY64_00060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mph(A) family macrolide 2'-phosphotransferase"
                     /protein_id="WP_000219391.1"
                     /translation="MTVVTTADTSQLYALAARHGLKLHGPLTVNELGLDYRIVIATVDD
                     GRRWVLRIPRRAEVSAKVEPEARVLAMLKNRLPFAVPDWRVANAELVAYPMLEDSTAMV
                     IQPGSSTPDWVVPQDSEVFAESFATALAALHAVPISAAVDAGMLIRTPTQARQKVADDV
                     DRVRREFVVNDKRLHRWQRWLDDDSSWPDFSVVVHGDLYVGHVLIDNTERVSGMIDWSE
                     ARVDDPAIDMAAHLMVFGEEGLAKLLLTYEAAGGRVWPRLAHHIAERLAFGAVTYALFA
                     LDSGNEEYLAAAKAQLAAAE"
                     /name="Mph(A) family macrolide 2'-phosphotransferase"
     gene            complement(9119..9823)
                     /locus_tag="CAY64_RS00070"
                     /old_locus_tag="CAY64_00070"
     CDS             complement(9119..9823)
                     /locus_tag="CAY64_RS00070"
                     /old_locus_tag="CAY64_00070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_004217321.1"
                     /translation="MNPFKGRHFQRDIIRWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            9814..11079
                     /locus_tag="CAY64_RS00075"
                     /old_locus_tag="CAY64_00075"
     CDS             9814..11079
                     /locus_tag="CAY64_RS00075"
                     /old_locus_tag="CAY64_00075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011846847.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="WP_004198116.1"
                     /translation="MGSCAAPSAKGDDKFITTDYLQQCQNNHVRPKDRKLLLTTILADG
                     INLGLTKMAESCPGTTKSSLEGIQAWYIRDETYSAALAELVNAQKKSPLAAFWGDGTTS
                     SSDGQNFRVGSHGRYAGQVNLKYGQDPSVQIYTHISDQYSPFYTKVISRVRDSTHVLDG
                     LLYHETDLEITEHYTDTAGFTEHVFALMHLLGFAFAPRIRDLHDKRLFIHGKAELYQGL
                     QSIISTTSLNLKEIETHWHEVLRLASSIKQGTVTASLMMKKLASYPKQNGLAKALREIG
                     RIERSLFMLDWFRDPLLRRRVQAGLNKGEARNALARAVFMHRLGEIRDRGLENQSYRAS
                     GLTLLTAAISLWNTVYIERAIDSLRRKGIPINEQLITHLSPLGWEHINLSGDYVWRTNL
                     KLGQGKYRALRSVNSNMYKKQA"
                     /name="Tn3 family transposase"
     gene            11158..12162
                     /locus_tag="CAY64_RS00080"
                     /old_locus_tag="CAY64_00080"
     CDS             11158..12162
                     /locus_tag="CAY64_RS00080"
                     /old_locus_tag="CAY64_00080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229637.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110-like element IS5075 family transposase"
                     /protein_id="WP_000427619.1"
                     /translation="MENIALIGIDLGKNSFHIHCQDHRGKAVYRKKFTRPKLIEFLATC
                     PATTIAMEACGGSHFMARKLEELGHFPKLISPQFVRPFVKSNKNDFVDAEAICEAASRP
                     SMRFVQPRTESQQAMRALHRVRESLVQDKVKTTNQMHAFLLEFGISVPRGAAVISRLST
                     LLEDSSLPLYLSQLLLKLQQHYHYLVEQIKDLESQLKRKLDEDEVGQRLLSIPCVGTLT
                     ASTISTEIGDGKQYASSRDFAAATGLVPRQYSTGGRTTLLGISKRGNKKIRTLLVQCAR
                     VFIQKLEHQSGKLADWVRELLCRKSNFVVTCALANKLARIAWALTARQQTYEA"
                     /name="IS110-like element IS5075 family transposase"
     gene            complement(12344..12616)
                     /locus_tag="CAY64_RS00085"
                     /old_locus_tag="CAY64_00085"
     CDS             complement(12344..12616)
                     /locus_tag="CAY64_RS00085"
                     /old_locus_tag="CAY64_00085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004883563.1"
                     /translation="MDSEEPPNVRVACSGDIDEVVRLMHDAAAWMSAKGTPAWDVARID
                     RTFAETFVLRSELLGIASENGIYGHSRFCNTDFDDKLACLNLSGV"
                     /name="hypothetical protein"
     gene            complement(12744..13583)
                     /gene="sul1"
                     /locus_tag="CAY64_RS00095"
                     /old_locus_tag="CAY64_00095"
     ARG             complement(12748..13583)
                     /name="sul1"
                     /gene="sul1"
                     /gene_name="sulfonamide-resistant dihydropteroate synthase
                     Sul1"
                     /tool="amrfinderplus"
                     /drug_class="SULFONAMIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(13577..13924)
                     /locus_tag="CAY64_RS00100"
                     /old_locus_tag="CAY64_00100"
     CDS             complement(13577..13924)
                     /locus_tag="CAY64_RS00100"
                     /old_locus_tag="CAY64_00100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter QacE delta 1"
                     /protein_id="WP_000679427.1"
                     /translation="MKGWLFLVIAIVGEVIATSALKSSEGFTKLAPSAVVIIGYGIAFY
                     FLSLVLKSIPVGVAYAVWSGLGVVIITAIAWLLHGQKLDAWGFVGMGLIIAAFLLARSP
                     SWKSLRRPTPW"
                     /name="quaternary ammonium compound efflux SMR transporter
                     QacE delta 1"
     gene            complement(14041..14879)
                     /locus_tag="CAY64_RS00105"
                     /old_locus_tag="CAY64_00105"
                     /pseudo=""
     CDS             complement(14041..14879)
                     /locus_tag="CAY64_RS00105"
                     /old_locus_tag="CAY64_00105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001749984.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="AadA family aminoglycoside
                     3''-O-nucleotidyltransferase"
                     /name="AadA family aminoglycoside
                     3''-O-nucleotidyltransferase"
     gene            complement(14885..15175)
                     /locus_tag="CAY64_RS00110"
                     /old_locus_tag="CAY64_00110"
     CDS             complement(14885..15175)
                     /locus_tag="CAY64_RS00110"
                     /old_locus_tag="CAY64_00110"
                     /inference="COORDINATES: protein motif:HMM:NF017990.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1010 domain-containing protein"
                     /protein_id="WP_001336345.1"
                     /translation="MFIQTAFSFSGVIQCLFCLFSGLRLHGLRRFSVFLASSPCVASAS
                     SYRFCSAVPPRWRSVFSRLAPVAKFKLSVLASGSNISVKPTRILRSAYLAR"
                     /name="DUF1010 domain-containing protein"
     gene            complement(15287..15784)
                     /gene="dfrA12"
                     /locus_tag="CAY64_RS00115"
                     /old_locus_tag="CAY64_00115"
     ARG             complement(15291..15784)
                     /name="dfrA12"
                     /gene="dfrA12"
                     /gene_name="trimethoprim-resistant dihydrofolate reductase
                     DfrA12"
                     /tool="amrfinderplus"
                     /drug_class="TRIMETHOPRIM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            15929..16942
                     /gene="intI1"
                     /locus_tag="CAY64_RS00120"
                     /old_locus_tag="CAY64_00120"
     CDS             15929..16942
                     /gene="intI1"
                     /locus_tag="CAY64_RS00120"
                     /old_locus_tag="CAY64_00120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1 integron integrase IntI1"
                     /protein_id="WP_000845039.1"
                     /translation="MKTATAPLPPLRSVKVLDQLRERIRYLHYSLPTEQAYVHWVRAFI
                     RFHGVRHPATLGSSEVEAFLSWLANERKVSVSTHRQALAALLFFYGKVLCTDLPWLQEI
                     GRPRPSRRLPVVLTPDEVVRILGFLEGEHRLFAQLLYGTGMRISEGLQLRVKDLDFDHG
                     TIIVREGKGSKDRALMLPESLAPSLREQLSRARAWWLKDQAEGRSGVALPDALERKYPR
                     AGHSWPWFWVFAQHTHSTDPRSGVVRRHHMYDQTFQRAFKRAVEQAGITKPATPHTLRH
                     SFATALLRSGYDIRTVQDLLGHSDVSTTMIYTHVLKVGGAGVRSPLDALPPLTSER"
                     /name="intI1"
     gene            <17145..>17381
                     /locus_tag="CAY64_RS29145"
                     /pseudo=""
     CDS             <17145..>17381
                     /locus_tag="CAY64_RS29145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003132006.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3330 domain-containing protein"
                     /name="DUF3330 domain-containing protein"
     gene            complement(17434..18138)
                     /locus_tag="CAY64_RS00130"
                     /old_locus_tag="CAY64_00130"
     CDS             complement(17434..18138)
                     /locus_tag="CAY64_RS00130"
                     /old_locus_tag="CAY64_00130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_001067855.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     ARG             complement(13581..13924)
                     /name="qacEdelta1"
                     /gene="qacEdelta1"
                     /gene_name="quaternary ammonium compound efflux SMR
                     transporter QacE delta 1"
                     /tool="amrfinderplus"
                     /drug_class="QUATERNARY AMMONIUM"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(8096..8997)
                     /name="mph(A)"
                     /gene="mph(A)"
                     /gene_name="Mph(A) family macrolide 2'-phosphotransferase"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(14092..14879)
                     /name="aadA2"
                     /gene="aadA2"
                     /gene_name="ANT(3'')-Ia family aminoglycoside
                     nucleotidyltransferase AadA2"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             72..883
                     /name="aph(3')-Ia"
                     /gene="aph(3')-Ia"
                     /gene_name="aminoglycoside O-phosphotransferase APH(3')-Ia"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(8093..8997)
                     /name="mphA"
                     /gene="mphA"
                     /gene_name="macrolide phosphotransferase (MPH)"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(14089..14867)
                     /name="aadA2"
                     /gene="aadA2"
                     /gene_name="ANT(3'')"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(6858..8095)
                     /name="Mrx"
                     /gene="Mrx"
                     /gene_name="macrolide phosphotransferase (MPH)"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="100.0"
                     /coverage="100.0"
ORIGIN
        1 acaagataaa aatatatcat catgaacaat aaaactgtct gcttacataa acagtaatac
       61 aaggggtgtt atgagccata ttcaacggga aacgtcttgc tcgaggccgc gattaaattc
      121 caacatggat gctgatttat atgggtataa atgggctcgc gataatgtcg ggcaatcagg
      181 tgcgacaatc tatcgattgt atgggaagcc cgatgcgcca gagttgtttc tgaaacatgg
      241 caaaggtagc gttgccaatg atgttacaga tgagatggtc agactaaact ggctgacgga
      301 atttatgcct cttccgacca tcaagcattt tatccgtact cctgatgatg catggttact
      361 caccactgcg atccccggga aaacagcatt ccaggtatta gaagaatatc ctgattcagg
      421 tgaaaatatt gttgatgcgc tggcagtgtt cctgcgccgg ttgcattcga ttcctgtttg
      481 taattgtcct tttaacagcg atcgcgtatt tcgtctcgct caggcgcaat cacgaatgaa
      541 taacggtttg gttgatgcga gtgattttga tgacgagcgt aatggctggc ctgttgaaca
      601 agtctggaaa gaaatgcata agcttttgcc attctcaccg gattcagtcg tcactcatgg
      661 tgatttctca cttgataacc ttatttttga cgaggggaaa ttaataggtt gtattgatgt
      721 tggacgagtc ggaatcgcag accgatacca ggatcttgcc atcctatgga actgcctcgg
      781 tgagttttct ccttcattac agaaacggct ttttcaaaaa tatggtattg ataatcctga
      841 tatgaataaa ttgcagtttc atttgatgct cgatgagttt ttctaatcag aattggttaa
      901 ttggttgtaa cactggcaga gcattacgct gacttgacgg gacggcgctt ccctaccctc
      961 atggccgcct cccaggaatc gacccaggtg cttatcgtgg acataatcct ttactcataa
     1021 attggcactg ttgcaaagtt agcgatgagg cagccttttg tcttattcaa aggccttaca
     1081 tttcaaaaac tctgcttacc aggcgcattt cgcccagggg atcaccataa taaaatgctg
     1141 aggcctggcc tttgcgtagt gcacgcatca cctcaatacc tttgatggtg gcgtaagccg
     1201 tcttcatgga tttaaatccc agcgtggcgc cgattatccg tttcagtttg ccatgatcgc
     1261 attcaatcac gttgttccgg tacttaatct gtcggtgttc aacgtcagac gggcaccggc
     1321 cttcgcgttt gagcagagca agcgcgcgac cataggcggg cgctttatcc gtgttgatga
     1381 atcgcgggat ctgccacttc ttcacgttgt tgaggatttt acccagaaac cggtatgcag
     1441 ctttgctgtt acgacgggag gagagataaa aatcgacagt gcggccccgg ctgtcgacgg
     1501 cccggtacag atacgcccag cggccattga ccttcacgta ggtttcatcc atgtgccacg
     1561 ggcaaagatc ggaagggtta cgccagtacc agcgcagccg tttttccatt tcaggcgcat
     1621 aacgctgaac ccagcggtaa atcgtggagt gatcgacatt cactccgcgt tcagccagca
     1681 tctcctgcag ctcacggtaa ctgatgccgt atttgcagta ccagcgtacg gcccacagaa
     1741 tgatgtcacg ctgaaaatgg ggtccgcttg gaaaacggaa tctatggtca ctcccgtttt
     1801 tgcaacaccg attttgacga caagttggct tgcttgaatc tatccggcgt ctgaatggga
     1861 ttttattccc gcgcctcgat gagttccgcg cctgatgaac ctccagaaaa tatacggctt
     1921 caatgagcct ttccgtttta caggttcctc aacaggccgg tgggccgtta gtatcatcaa
     1981 tatcagtatt cgcaaaacca gatgaatgat tgtttaaact ggtgtatttc tgcctttatg
     2041 cttcgtaagt ttgctgtcgc gccgtcagtg cccaggctat tctggccagc ttgtttgcca
     2101 gagcacaggt gacgacaaag ttgcttttcc gacacaacaa ctccctgacc cagtcggcca
     2161 acttgccaga ctggtgttcc agtttttgta tgaataccct ggcacactga accaacaaag
     2221 ttcggatctt tttgttgccc cgcttgctaa tccctaacaa tgtcgtccga cctcccgtgc
     2281 tgtactgtcg gggtaccagc cctgttgccg ccgcaaagtc acggctgctg gcgtactgct
     2341 tcccgtcgcc aatctcagtt gaaatagtac tggcagtcag cgttccaacg cagggaatac
     2401 tcagcaagcg ctgtccaacc tcatcttcgt ccaactttcg tttcaactga gattccagat
     2461 ctttaatctg ctcaacaaga tagtgataat gctgttgtaa tttcagcagt aactggctga
     2521 gataaagagg caaactactg tcctcaagaa gggtactcag tcgactaata acggcagcac
     2581 ctcgcggaac gctgatacca aattccagca gaaaagcatg catctgatta gttgttttca
     2641 ccttatcctg aaccagggat tcacggacac gatgcagagc tcgcattgcc tgctgagatt
     2701 cggttctggg ctgcacgaaa cgcatagatg gacgtgatgc tgcttcacag atagcttcag
     2761 catcaacgaa gtcatttttg ttgcttttaa cgaatgggcg gacaaattgc ggtgatatca
     2821 gctttggaaa atgccctaac tcttccagct tgcgtgccat aaagtgagaa ccgccacagg
     2881 cttccatcgc gatggttgtt gccgggcatg tcgccagaaa ttcgattagc tttggtcggg
     2941 tgaatttttt acggtaaacg gccttcccac gatgatcctg acaatgaata tggaaagagt
     3001 tcttacccag atcgatacca ataagcgcaa tgttttccat gatggttctc cgaatgaaag
     3061 cctgtcctca gcatagtact gggaaggagg gagtgaccat ctcattaaat aaagcacgct
     3121 aagccgtaag taagcgtgct cctgtgaaag ccacagctaa aactgcgtag tacacataga
     3181 ggtatttttt tctagattta tatcgaattt cgttatcgaa tttcgcttat tattgatcaa
     3241 ctcgttgcag atcatgaagg cgaaagtatg acgaataacc ctaccgatga cagcagacca
     3301 tggtcggtct ttcttatttt tctgcggctt ggattgacat cttttggcgg ccccattgcg
     3361 cacttgggct acttccgcgc cgaatttgtc acacggcggc gctggctctc cgaacggagc
     3421 tatgctgact tggtcgcgct ttgtcagttc ttgccagggc ctgcaagcag ccaggtcggc
     3481 atagcggtag gactgtctcg ggctggatac agcggggcgc tggctgcttg ggctggcttc
     3541 acgctgccgt ctgccatagc cttgatcctt tttgcgctcg gcatctccag ctatggcgat
     3601 tacgtctcgc agggcgcgtt gcatggctta aaagtggtgg ctgtggccgt ggtcgctcaa
     3661 gcagtatggg gcatggcgcg taacctatgc acggatgggc tgcgagtcac catcatggca
     3721 attgctacct gcgtcgtttt acttgtgccg tccgcgtggg gacaggttgg cgtgattgct
     3781 atcgcaggca tcgcaggccg gttattgttc aagccagcga aagttgttga gcatgacccc
     3841 ctacctatca cggtcagtca ccgggccggc gtgctttggc tctcgctgtt ctttgtcttg
     3901 ctgattggcc tgccggtgtt ggccgaactg atgccaagtc aaaccatggc aatggtggat
     3961 tccttctatc gtgtcggatc actggtgttc ggcggtggtc acgttgtgct gccattactg
     4021 caagccgaag tggtgccctc cggctgggtc aacaatgaat cctttctcgc ggggtacggg
     4081 gcagctcaag cggtgcccgg ccctttgttc acgttcgccg cgtttcttgg tgcctcgatg
     4141 aacaccgccc cgtcgggctg gatcggcggc attgtgtgtc tgctggctat cttcgcgccc
     4201 tcgttcttgc tggtcgtcgg atcaatgcca ttttgggagc gtttgcgccg caatacaggc
     4261 atccaagctg cgctggccgg gatcaatgcc gctgtagtcg gcttgctgct ggccgcgctg
     4321 tatcagcctg tatggactag cgccatcttt cagccgcaag acttcggctt ggcattagtt
     4381 gcccttgtcg cacttatgtt ctggaagctc ccgccgtggc tggttgtcct cggtagcggt
     4441 gcagctgggt ggctgttgag cgtcgctctg tgaggcacaa aaaatgactg acaaagacct
     4501 ctacggcggt ttgatccgcc tgcacatcct tcaccatgca gccgaggaac ctgtctttgg
     4561 gctggggatc atcgaagagc tacgccgaca cggctacgag atgagcgctg gcaccgtgta
     4621 cccgatgctg cacggcctgg aaaaaaaagg ctatctgacc tcacgccacg aacgcaccgg
     4681 gcgacgtgaa cggcgtgttt atgacatcac tgaacaaggc agaactgcac ttgctgatgc
     4741 gaaaacaaag gtcaaggagc tgttcggaga gttggtagaa ggtggttgag tttttgcttc
     4801 tatgtcaggt tgagctatac cctaactgga ttgtcatttt cagaagacga ctgcaccagt
     4861 tgattgggcg taatggctgt tgtgcagcca gctcctgaca gttcaatatc agaagtgatc
     4921 tgcaccaatc tcgactatgc tcaatactcg tgtgggctct gttgcaaaaa tcgtgaagct
     4981 tgagcatgct tggcggagat tggacggacg gaacgatgac ggatttcaag tggcgccatt
     5041 tccagggtga tgtgatcctg tgggcggtgc gctggtattg tcgctatccg atcagctatc
     5101 gcgaccttga ggaaatgctg gcggaacgcg gcatttcggt cgaccatacg acgatctatc
     5161 gctgggtcca gtgctacgcc ccggagatgg agaagcggct gcgctggttc tggcggcgtg
     5221 gctttgatcc gagctggcgc ctggatgaaa cctacgtcaa ggtgcggggc aagtggacct
     5281 acctgtaccg ggcagtcgac aagcggggcg acacgatcga tttctacctg tcgccgaccc
     5341 gcagcgccaa ggcagcgaag cggttcctgg gcaaggccct gcgaggcctg aagcactggg
     5401 aaaagcctgc cacgctcaat accgacaaag cgccgagcta tggtgcagcg atcaccgaat
     5461 tgaagcgcga aggaaagctg gaccgggaga cggcccaccg gcaggtgaag tatctcaata
     5521 acgtgatcga ggccgatcac ggaaagctca agatactgat caagccggtg cgcggtttca
     5581 aatcgatccc cacggcctat gccacgatca agggattcga agtcatgcga gccctgcgca
     5641 aaggacaggc tcgcccctgg tgcctgcagc ccggcatcag gggcgaggtg cgccttgtgg
     5701 agagagcttt tggcattggg ccctcggcgc tgacggaggc catgggcatg ctcaaccacc
     5761 atttcgcagc agccgcctga tcggcgcaga gcgacagcct acctctgact gccgccaatc
     5821 tttgcaacag agcccgccgt gctagtctgc tcggtgatgg tggagtgaag ccaacccgca
     5881 atcgggttat gaatctgcat cgcgattcgc aatcagctgt ctcttgagca tgtcgaactc
     5941 ctgcgatgtt atctcgccgt gctcgtgctg ctacaccaac ttgtccaact catccgccac
     6001 accgctcccc accacctgcg atggccaggt tgtttgctgg gcgcattggc ggagtatcgt
     6061 ctcgacccgg gacacccaca ccggcacaac cttacgggag tgattcactg tcaaagaatc
     6121 ggcccggtgc tctgacgcaa gtatcgggat ggtcaccatt tgtaagccgt agacctgagt
     6181 ggtgatcaag acttcgatac caccgaccgt accggtacta atcgacgacg gtcgtgttcg
     6241 tcgcctgccg cagggactct gcacacctcc gtttacgcat gtgcctggag gagttggaaa
     6301 tcgtcgtgtt cgggaaacat taaacacagg atggcagcga tctgagccag cacatgatca
     6361 gctagctcac catccggatc gacggcccac tgcatcgtcg cgccagcgat gaccgagtgc
     6421 aggagcaact cagctgccgc aggagcacct gggggcagtc gcttgcggat cccctccacc
     6481 accgcgcggt tccgctggat cgcaagcgtg cgtagctccg gcacctggag ctcgtaccag
     6541 gagatgagat agttcaccga gaagtcgttg cgagtgttca tgctccgaac gagcacctgc
     6601 aaaaattccc agagcccttg cggccctgcg cctatcggta tcgcattcag gtaatgccgc
     6661 acctgctcga cgccgcgctc catcatcctc accagcagcg tatcgcggtt ggtgaagcgc
     6721 tggattaacg ctgcgcggga gagccccacc tcctttgcta ctccgctgag cgtgaactct
     6781 atgggaccgc aacgcttcag cactacggtg gcggcctcga gtacctcgtc atcggacttg
     6841 agcttggggc ggggcatcag tgttcacctt ctgtatgggt tggggcggag gctgtggctg
     6901 ccgccgccat tgtagcaaat tgaagacgga gcgagagtag agccacgagc cccgcaaaca
     6961 cggccgatac aacgaggcca gggagcggac cagcaaggtc gacaaacgcg ccggccgcaa
     7021 gcataaccat gggcgaggct gacagcatca ccgccgagac cgtgccgagt acccggccga
     7081 gaagttctgg cggcgtgcgg ttgtagatgg cagcgttgag aatgggagag actgagccgg
     7141 tcagcagtcc cacgagcgcg cccaacaaca tcagcaccgg cacgcctggc aactgtgaaa
     7201 gcagaagcga gcccaccgca gagccacaaa atgccaccgc cagccagttc tgcgctgata
     7261 tccgggcgcc gaccgacgca tgaatggcaa tgccaaggag accaccagcc cccatcattg
     7321 aggagaacag cccgagctct gctacttggc gtcctgcatc tacaaacagc gcaggcatga
     7381 tgacgctgcc gttggcgcca acgatgccca cgaagatcat cactatacca aagagagggc
     7441 gcagcagggg ttcgctccag agaaaagcga cgccggcgcg catggagaga gtcgccgtcg
     7501 tggtcatcgt ccgagcggca cgcgcgggaa gcacccacgc gccgagcaga cctgcaagga
     7561 cggagcagaa cgccgtcagc ccgagcgttg gcgcagcgcc aagcaggccg attgcggccc
     7621 ccccaagggc cgggccacct agaatcgcga cgttcccgat caccgctttc agtgacgaga
     7681 cgcgctcaac ggagagcccg gcgacgtggc cgagtttggg cagctcactg tcctgcgcgg
     7741 ccataccggg tgcgtcgaac gcggcaccga gcaccacgca agcgatcagc ccagtgttcg
     7801 agagggcgcc aacggcatcg agcagtggga tgctcgccat ggccacgccg cccaccacac
     7861 ccgagatcaa tgcgacgggc gcgcgcccga accgatcgac gaggccacca ccaacccacg
     7921 cgccgatgat ggtcgcgatg acgctgctag cggccgtggc gcccgcccag gccgcgctct
     7981 ttgtatgaga caggacgaac catggaagcg cgagggccgc caccgcgttg ccgatccgga
     8041 agagaaaggt cgccgcgaac agcgtcgcga gcgggctata tcgacgttcg ctcattccgc
     8101 tgcggcgagc tgcgccttcg ccgcagcgag gtactcttcg ttacccgagt cgagggcgaa
     8161 gagtgcgtag gtgaccgccc cgaacgcaag gcgctccgcg atgtggtggg cgagccgcgg
     8221 ccacacccgg ccaccggccg cttcatacgt gaggaggagc ttcgcgagcc cctcttcacc
     8281 aaagaccata aggtgcgcgg ccatgtcgat ggcagggtca tcaacgcggg cctcgctcca
     8341 gtcgatcatc ccgctgacgc gctccgtgtt gtcgatgagc acatggccca cgtagagatc
     8401 gccatgcacc accacggaga aatctggcca cgacgaatcg tcgtcgagcc agcgctgcca
     8461 ccggtggagg cgcttgtcgt tcaccacgaa ctcgcgtcgg acgcggtcaa cgtcgtcggc
     8521 caccttctga cgggcctgcg tcggtgtacg gatgagcatc cccgcatcca cggcggcgga
     8581 aatggggacg gcatgcaggg cggcgagcgc ggtcgcgaag ctctccgcga agacctccga
     8641 gtcctgcggc acgacccagt cgggcgtgga cgaaccaggc tggatgacca tcgcagtcga
     8701 gtcttcgagc atgggatagg caacgagctc ggcgttggcc acgcgccagt ccggcaccgc
     8761 gaacggcagg cgattcttga gcattgccag cacccgcgcc tctggttcga ccttcgcgct
     8821 tacctcggct cggcgcggga tgcgcagcac ccaccgacgt ccatcgtcga cggtggcgat
     8881 cacgatccta tagtcgagcc caagctcatt gacagtcagc gggccatgga gcttgagccc
     8941 atgtcgggct gcaagtgcgt acagttggga ggtatcggcg gtcgtgacta cggtcatgat
     9001 tcactcctga gggcttgacg ggtttagcca cctaaatgta acagtcacgt cggttatatt
     9061 caatccggca ctgttgcaaa gttagcgatg aggcagcctt ttgtcttatt caaaggcctt
     9121 acatttcaaa aactctgctt accaggcgca tttcgcccag gggatcacca taataaaatg
     9181 ctgaggcctg gcctttgcgt agtgcacgca tcacctcaat acctttgatg gtggcgtaag
     9241 ccgtcttcat ggatttaaat cccagcgtgg cgccgattat ccgtttcagt ttgccatgat
     9301 cgcattcaat cacgttgttc cggtacttaa tctgtcggtg ttcaacgtca gacgggcacc
     9361 ggccttcgcg tttgagcaga gcaagcgcgc gaccataggc gggcgcttta tccgtgttga
     9421 tgaatcgcgg gatctgccac ttcttcacgt tgttgaggat tttacccaga aaccggtatg
     9481 cagctttgct gttacgacgg gaggagagat aaaaatcgac agtgcggccc cggctgtcga
     9541 cggcccggta cagatacgcc cagcggccat tgaccttcac gtaggtttca tccatgtgcc
     9601 acgggcaaag atcggaaggg ttacgccagt accagcgcag ccgtttttcc atttcaggcg
     9661 cataacgctg aacccagcgg taaatcgtgg agtgatcgac attcactccg cgttcagcca
     9721 gcatctcctg cagctcacgg taactgatgc cgtatttgca gtaccagcgt acggcccacc
     9781 gaatgatgtc acgctgaaaa tgccggcctt tgaatgggtt catgtgcagc tccatcagca
     9841 aaaggggatg ataagtttat caccaccgac tatttgcaac agtgccaaaa caatcacgtc
     9901 agacctaaag acagaaagtt gttactgacc accatcctgg ccgatggtat caaccttgga
     9961 ctgacaaaaa tggccgaatc ctgtccggga acgaccaaat cgtcactcga gggcattcag
    10021 gcctggtaca tcagggatga aacctattca gctgcgctgg ccgagttggt caatgcccag
    10081 aaaaaaagcc ctctggcggc attctggggc gatggaacaa cgtcatcgtc tgatggacag
    10141 aactttcggg tggggagtca cgggcgttat gctggtcagg tcaatcttaa atacggtcag
    10201 gatccaagcg tgcagattta tacgcatatt tcggaccaat acagcccgtt ttacaccaaa
    10261 gttatcagcc gcgtgcggga ttcaacacac gtacttgatg gtctgctgta ccacgaaact
    10321 gatctggaaa ttacagagca ttacaccgac acagcaggtt tcactgagca tgtttttgcg
    10381 ctaatgcatc tgctcggatt cgcttttgcg ccaaggatcc gggatcttca tgacaaacgg
    10441 ctgtttattc atggaaaagc tgagttgtat caggggcttc agtcaatcat ctcgacaacc
    10501 agcctgaatc taaaggaaat tgaaacccac tggcatgagg tgctgcgtct ggcaagttct
    10561 ataaagcagg gaacggtaac agcatcactg atgatgaaaa agctggcaag ctatccgaag
    10621 cagaatggtc tggcaaaggc gctgagagag attggccgca tcgaaaggtc attgtttatg
    10681 ctggactggt tcagggatcc tttactgcgt cgacgcgtac aggcggggct gaataaaggt
    10741 gaggctcgca atgcccttgc gcgagcggtc tttatgcatc ggctgggtga aatcagagat
    10801 cgggggctgg agaatcagag ctatcgagcc agcggtctga cgttgctgac tgcggcgatc
    10861 tcactgtgga atacggtata tatagaaaga gcgatagatt ctttgagacg aaaagggatc
    10921 ccgattaatg agcaactgat tacccatctg tcaccactgg gatgggaaca tatcaacctg
    10981 agcggggatt acgtctggag aacgaacctc aaactgggac agggtaaata ccgcgcatta
    11041 cgctcagtga atagtaatat gtacaaaaaa caggcttagc gtaggataat taatgagatg
    11101 gtcactccct ccttcccagt actatgctga ggacaggctt tcattcggag aaccatcatg
    11161 gaaaacattg cgcttattgg tatcgatctg ggtaagaact ctttccatat tcattgtcag
    11221 gatcatcgtg ggaaggccgt ttaccgtaaa aaattcaccc gaccaaagct aatcgaattt
    11281 ctggcgacat gcccggcaac aaccatcgcg atggaagcct gtggcggttc tcactttatg
    11341 gcacgcaagc tggaagagtt agggcatttt ccaaagctga tatcaccgca atttgtccgc
    11401 ccattcgtta aaagcaacaa aaatgacttc gttgatgctg aagctatctg tgaagcagca
    11461 tcacgtccat ctatgcgttt cgtgcagccc agaaccgaat ctcagcaggc aatgcgagct
    11521 ctgcatcgtg tccgtgaatc cctggttcag gataaggtga aaacaactaa tcagatgcat
    11581 gcttttctgc tggaatttgg tatcagcgtt ccgcgaggtg ctgccgttat tagtcgactg
    11641 agtacccttc ttgaggacag tagtttgcct ctttatctca gccagttact gctgaaatta
    11701 caacagcatt atcactatct tgttgagcag attaaagatc tggaatctca gttgaaacga
    11761 aagttggacg aagatgaggt tggacagcgc ttgctgagta ttccctgcgt tggaacgctg
    11821 actgccagta ctatttcaac tgagattggc gacgggaagc agtacgccag cagccgtgac
    11881 tttgcggcgg caacagggct ggtaccccga cagtacagca cgggaggtcg gacgacattg
    11941 ttagggatta gcaagcgggg caacaaaaag atccgaactt tgttggttca gtgtgccagg
    12001 gtattcatac aaaaactgga acaccagtct ggcaagttgg ccgactgggt cagggagttg
    12061 ttgtgtcgga aaagcaactt tgtcgtcacc tgtgctctgg caaacaagct ggccagaata
    12121 gcctgggcac tgacggcgcg acagcaaact tacgaagcat aaaggcagaa atacaccagt
    12181 ttaaacaatc attcatctgg ttttgcgaat actgatattg atgatactaa cggcccaccg
    12241 gcctgttgag gaacctgtaa aacggaaagg ctcattgaag ccgtatattt tctggaggtt
    12301 catcaggcgc ggaactcatc gaggcgcggg aataaaatcc cattcagacg ccggatagat
    12361 tcaagcaagc caacttgtcg tcaaaatcgg tgttgcaaaa acgggagtga ccatagattc
    12421 cgttttctga ggcgatccct aggagctcgg atctcaggac gaaggtctcc gcgaatgtcc
    12481 ggtcgatccg cgcgacgtcc caggcgggcg ttcccttggc ggacatccac gccgcagcgt
    12541 cgtgcatcag ccgcacaacc tcgtcgatat cacccgagca ggcgacccga acgttcggag
    12601 gctcctcgct gtccattcgc tcccctggcg cggtatgaac cgccgcctca tagtgcagtt
    12661 tgatcctgac gagcccagca tgtctgcgcc caccttcgcg gaacctgacc agggtccgct
    12721 agcgggcggc cggaaggtga atgctaggca tgatctaacc ctcggtctct ggcgtcgcga
    12781 ctgcgaaatt tcgcgagggt ttccgagaag gtgattgcgc ttcgcagatc tccaggcgcg
    12841 tgggtgcgga cgtagtcagc gccattgccg atcgcgtgaa gttccgccgc aaggctcgct
    12901 ggacccagat cctttacagg aaggccaacg gtggcgccca agaaggattt ccgcgacacc
    12961 gagaccaata gcggaagccc caacgccgac ttcagctttt gaaggttcga cagcacgtgc
    13021 agcgatgttt ccggtgcggg gctcaagaaa aatcccatcc ccggatcgag gatgagccgg
    13081 tcggcagcga ccccgctccg tcgcaaggcg gaaacccgcg cctcgaagaa ccgcacaatc
    13141 tcgtcgagcg cgtcttcggg tcgaaggtga ccggtgcggg tggcgatgcc atcccgctgc
    13201 gctgagtgca taaccaccag cctgcagtcc gcctcagcaa tatcgggata gagcgcaggg
    13261 tcaggaaatc cttggatatc gttcaggtag cccacgccgc gcttgagcgc atagcgctgg
    13321 gtttccggtt ggaagctgtc gattgaaaca cggtgcatct gatcggacag ggcgtctaag
    13381 agcggcgcaa tacgtctgat ctcatcggcc ggcgatacag gcctcgcgtc cggatggctg
    13441 gcggccggtc cgacatccac gacgtctgat ccgactcgca gcatttcgat cgccgcggtg
    13501 acagcgccgg cggggtctag ccgccggctc tcatcgaaga aggagtcctc ggtgagattc
    13561 agaatgccga acaccgtcac catggcgtcg gcctccgcag cgacttccac gatggggatc
    13621 gggcgagcaa aaaggcagca attatgagcc ccatacctac aaagccccac gcatcaagct
    13681 tttgcccatg aagcaaccag gcaatggctg taattatgac gacgccgagt cccgaccaga
    13741 ctgcataagc aacaccgaca gggatggatt tcagaaccag agaaagaaaa taaaatgcga
    13801 tgccataacc gattatgaca acggcggaag gggcaagctt agtaaagccc tcgctagatt
    13861 ttaatgcgga tgttgcgatt acttcgccaa ctattgcgat aacaagaaaa agccagcctt
    13921 tcatgatata tctcccaatt tgtgtagggc ttattatgca cgcttaaaaa taataaaagc
    13981 agacttgacc tgatagtttg gctgtgagca attatgtgct tagtgcatct aacgccggag
    14041 ttaagccgcc gcgcgtagcg cggtcggctt gaacgaattg ttagacatca tttaccaact
    14101 gacttgatga tctcgccttt cacaaagcga ataaattctt ccaagtgatc tgcgcgtgag
    14161 gccaagtgat cttctttttg tcccagataa gcttgcttag cttcaagtaa gacgggctga
    14221 tactgggcag gtaggcgttt tattgcccag tcggcagcga catccttcgg cgcgattttg
    14281 ccggttattg cgctgtacca aatgcgggac aacgtaagca ctacatttcg ctcatcgccg
    14341 gcccagtcgg gctgcgagtt ccatagcttc aaggtttccc tcagcgcctc gaatagatcc
    14401 tgttcaggaa ccgggtcaaa gaattcctcc gctgccggac ctaccaaggc aacgctatgt
    14461 tctcttgctt ttgtaagcag gatagctaga tcaatgtcga tcatggctgg ctcgaagata
    14521 cccgcaagaa tgtcattgcg ctgccattct ccaaattgca gctcgcgctt agccggataa
    14581 cgccacggga tgatgtcgtc atgcacgaca agggtgactt ctatagcgcg gagcgtctcg
    14641 ctctcgccag ggaaagccga agcctccata agatcattga gcaatgctcg ccgcgtcgtt
    14701 tcatcaagct ttacggccac agtaaccaac aaatcaatat cgctgtatgg cttcaggccg
    14761 ccatccactg cggagccgta caaatgcacg gccagcaacg ttgattccag atggcgctca
    14821 atgacgctta gcacctctga tagttggttc gaaatttcga tggtcaccgc ttccctcatg
    14881 atgtctaacg ggcgaggtaa gccgaccgca gaatgcgggt cggcttgacc gaaatgttag
    14941 aaccagaagc caaaacggat aacttgaatt tggcgacggg cgctaaccgt gaaaaaacgc
    15001 tgcgccaccg aggcggcaca gcactgcaaa aacgatagct gcttgcgctt gctacgcaag
    15061 ggctagaggc caaaaagact gaaaacctgc gcagcccatg caggcgaagc ccggaaaaaa
    15121 ggcaaaacag gcactgaata acgcctgaaa agctaaatgc cgtttgaata aacatgagct
    15181 aaataaagct gggtttcagt ggtgctaacg ttggacgtaa cgagagccgg agcgcagcgg
    15241 agggaaccaa aatgcgcagc attttggcgt cccgttgacg gaatggttag ccgtttcgac
    15301 gcgcataaac ggagtgggtg tacggaatta cagcttgaat ggtttcggtt gagacaagct
    15361 cgaattctgt ttcgttgagc attgggaaga aggcgtcacc ctcgaaggtt tgatgtacct
    15421 cagatagaaa cacgccgtgg gcgtgaggta gtgccagagt gtatatctca gctccgcccg
    15481 cgacgtagag ttcattgccg agttcggatg ccaaagcgat agcgtgcgac agcgttgaaa
    15541 caactacgca gccagtggcg cggtagttag cttggcgtga gattaccaat gtgtgacggt
    15601 tcggtagagg cttgccgata gactcaaagg tctttcgccc catgacaacg acttttccct
    15661 cagtgagtct gcgaaaaatc ttctgctcac ccggaatttt ccaggggata ttaggaccat
    15721 tgccaataac ccgattggct cccatcgcag caacgagata aatgcgtact gattccgagt
    15781 tcatatggct aactttgttt tagggcgact gccctgctgc gtaacatcgt tgctgctcca
    15841 taacatcaaa catcgaccca cggcgtaacg cgcttgctgc ttggatgccc gaggcataga
    15901 ctgtacaaaa aaacagtcat aacaagccat gaaaaccgcc actgcgccgt taccaccgct
    15961 gcgttcggtc aaggttctgg accagttgcg tgagcgcata cgctacttgc attacagctt
    16021 accaaccgaa caggcttatg tccactgggt tcgtgccttc atccgtttcc acggtgtgcg
    16081 tcacccggca accttgggca gcagcgaagt cgaggcattt ctgtcctggc tggcgaacga
    16141 gcgcaaggtt tcggtctcca cgcatcgtca ggcattggcg gccttgctgt tcttctacgg
    16201 caaggtgctg tgcacggatc tgccctggct tcaggagatc ggaagacctc ggccgtcgcg
    16261 gcgcttgccg gtggtgctga ccccggatga agtggttcgc atcctcggtt ttctggaagg
    16321 cgagcatcgt ttgttcgccc agcttctgta tggaacgggc atgcggatca gtgagggttt
    16381 gcaactgcgg gtcaaggatc tggatttcga tcacggcacg atcatcgtgc gggagggcaa
    16441 gggctccaag gatcgggcct tgatgttacc cgagagcttg gcacccagcc tgcgcgagca
    16501 gctgtcgcgt gcacgggcat ggtggctgaa ggaccaggcc gagggccgca gcggcgttgc
    16561 gcttcccgac gcccttgagc ggaagtatcc gcgcgccggg cattcctggc cgtggttctg
    16621 ggtttttgcg cagcacacgc attcgaccga tccacggagc ggtgtcgtgc gtcgccatca
    16681 catgtatgac cagacctttc agcgcgcctt caaacgtgcc gtagaacaag caggcatcac
    16741 gaagcccgcc acaccgcaca ccctccgcca ctcgttcgcg acggccttgc tccgcagcgg
    16801 ttacgacatt cgaaccgtgc aggatctgct cggccattcc gacgtctcta cgacgatgat
    16861 ttacacgcat gtgctgaaag ttggcggtgc cggagtgcgc tcaccgcttg atgcgctgcc
    16921 gcccctcact agtgagaggt agggcagcgc aagtcaatcc tggcggattc actacccctg
    16981 cgcgaaggcc atcggtgccg catcgaacgg ccggttgcgg aaagtcctcc ctgcgtccgc
    17041 tgatggccgg cagcagcccg tcgttgcctg atggatccaa cccctccgct gctatagtgc
    17101 agtcggcttc tgacgttcag tgcagccgtc ttctgaaaac gacaatggag gtggtagccg
    17161 agggtgtgga aacacccgac tgccttgcgt ggttgcggca ggcgggttgc gacacggtgc
    17221 agggtttcct gttcgccagg ccgatgccgg cggcggcctt cgtcggcttc gtcaaccaat
    17281 ggaggaacac caccatgaac gccaatgaac cgagcaccag ttgctgcgtg tgctgcaagg
    17341 aaatcccgct cgatgccgcc ttcacgccgg aaggggccga gggcactgtt gcaaagttag
    17401 cgatgaggca gccttttgtc ttattcaaag gccttacatt tcaaaaactc tgcttaccag
    17461 gcgcatttcg cccaggggat caccataata aaatgctgag gcctggcctt tgcgtagtgc
    17521 acgcatcacc tcaatacctt tgatggtggc gtaagccgtc ttcatggatt taaatcccag
    17581 cgtggcgccg attatccgtt tcagtttgcc atgatcgcat tcaatcacgt tgttccggta
    17641 cttaatctgt cggtgttcaa cgtcagacgg gcaccggcct tcgcgtttga gcagagcaag
    17701 cgcgcgacca taggcgggcg ctttatccgt gttgatgaat cgcgggatct gccacttctt
    17761 cacgttgttg aggattttac ccagaaaccg gtatgcagct ttgctgttac gacgggagga
    17821 gagataaaaa tcgacagtgc ggccccggct gtcgacggcc cggtacagat acgcccagcg
    17881 gccattgacc ttcacgtagg tttcatccat gtgccacggg caaagatcgg aagggttacg
    17941 ccagtaccag cgcagccgtt tttccatttc aggcgcataa cgctgaaccc agcggtaaat
    18001 cgtggagtga tcgacattca ctccgcgttc agccagcatc tcctgcagct cacggtaact
    18061 gatgccgtat ttgcagtacc agcgtacggc ccacagaatg atgtcacgct gaaaatgccg
    18121 gcctttgaat gggttcatgt gcagctccat cagcaaaagg ggatgataag tttatcacca
    18181 ccgactattt gcaacagtgc cctctgatgt tacattgc
//
