LOCUS       NZ_CP031381            24268 bp    DNA     circular CON 23-NOV-2023
DEFINITION  Acinetobacter baumannii ACICU plasmid pACICU1b, complete sequence.
ACCESSION   NZ_CP031381
VERSION     NZ_CP031381.2
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN09302593
            Assembly: GCF_005519135.2
KEYWORDS    RefSeq.
SOURCE      Acinetobacter baumannii ACICU
  ORGANISM  Acinetobacter baumannii ACICU
            Bacteria; Pseudomonadota; Gammaproteobacteria; Moraxellales;
            Moraxellaceae; Acinetobacter; Acinetobacter calcoaceticus/baumannii
            complex.
REFERENCE   1  (bases 1 to 24268)
  AUTHORS   Hartstein,R.M., Hamidian,M., Nigro,S.J., Wick,R., Judd,L., Holt,K.
            and Hall,R.M.
  TITLE     Multiply antibiotic resistant Acinetobacter baumannii global clone 2
            isolates carrying an AbaR-type island in comM
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 24268)
  AUTHORS   Hartstein,R.M., Hamidian,M., Nigro,S.J., Wick,R., Judd,L., Holt,K.
            and Hall,R.M.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-APR-2021) School of Life and Environmental Sciences,
            The University of Sydney, Molecular BioScience Building G08,
            Darlington, Sydney, NSW 2008, Australia
  REMARK    Sequence update by submitter
REFERENCE   3  (bases 1 to 24268)
  AUTHORS   Hartstein,R.M., Hamidian,M., Nigro,S.J., Wick,R., Judd,L., Holt,K.
            and Hall,R.M.
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JUL-2018) School of Life and Environmental Sciences,
            The University of Sydney, Molecular BioScience Building G08,
            Darlington, Sydney, NSW 2008, Australia
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2017
            Assembly Method                   :: Unicycler v. 1.00
            Assembly Name                     :: ACICU
            Expected Final Version            :: yes
            Genome Coverage                   :: 243.0x
            Sequencing Technology :: Illumina MiSeq; MinION (Nanopore)
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/23/2023 03:59:41
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,850
            CDSs (total)                      :: 3,756
            Genes (coding)                    :: 3,689
            CDSs (with protein)               :: 3,689
            Genes (RNA)                       :: 94
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 25 of 67
            Pseudo Genes (incomplete)         :: 37 of 67
            Pseudo Genes (internal stop)      :: 13 of 67
            Pseudo Genes (multiple problems)  :: 8 of 67
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP031381.2.
            On Oct 28, 2021 this sequence version replaced NZ_CP031381.1.
            Annotated using prokka 1.13 from
            https://github.com/tseemann/prokka, with manual annotation of
            important features.
            Bacteria and source DNA available from Ruth Hall, The University of
            Sydney NSW Australia; ruth.hall@sydney.edu.au.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..24268
                     /organism="Acinetobacter baumannii ACICU"
                     /mol_type="genomic DNA"
                     /strain="ACICU"
                     /isolation_source="cerebrospinal fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:405416"
                     /plasmid="pACICU1b"
                     /geo_loc_name="Italy: Rome"
                     /lat_lon="41.8857 N 12.5024 E"
                     /collection_date="2005"
                     /collected_by="ICU, Hospital S. Giovanni-Addolorata"
     gene            164..1114
                     /gene="repM"
                     /locus_tag="DMO12_RS18655"
                     /old_locus_tag="DMO12_20003"
     CDS             164..1114
                     /gene="repM"
                     /locus_tag="DMO12_RS18655"
                     /old_locus_tag="DMO12_20003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004786597.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein RepM"
                     /protein_id="WP_001205343.1"
                     /translation="MRDLVVKDNALINASYNLDLVEQRLILLAIVEARESGKGINANDP
                     LEVHADSYINQFGVHRNTAYQALKDACKDLFARQFSYQEKKANGNIRNVMSRWVSQIAY
                     NDNEATVDLIFAPAVVPFITRLEEQFTKYELQQVSSLSSAYAIRLYELLIQWRSTGKTP
                     TIELQEFRKKLGVLDNEYLRMAHLKERVLELSIKQINEHTDITVKYEQHKRGRSISGFS
                     FTFKQKKKDSPSIERDPNTLELFSKMTDAQRHMFANKLSELPEMGRYSQGTESYQQFAV
                     RIAEMLQDPAQFKELYPYLKKVGYMPSNKKDTVNG"
                     /name="repM"
     gene            1107..1682
                     /locus_tag="DMO12_RS18660"
                     /old_locus_tag="DMO12_20006"
     CDS             1107..1682
                     /locus_tag="DMO12_RS18660"
                     /old_locus_tag="DMO12_20006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005102333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid replication DNA-binding protein"
                     /protein_id="WP_001096616.1"
                     /translation="MAKLSLSEVSKKFHVDRSTIYRAVRNGRLSRSSDGQFDLAEVIRC
                     FGEPEQTSQKIESSKQEGDESTKKLIAHLENEVKKYQEREERLMQQIDRMQTLIELKSV
                     APATAAPHQDATACDTKMPQHATTQQDTDNKKNNELNIAENVAVPQQETTAYHTQTLQH
                     ATLQSVAVPQHKKRGLFGRVLNAVFDND"
                     /name="plasmid replication DNA-binding protein"
     gene            1702..1845
                     /locus_tag="DMO12_RS18665"
                     /old_locus_tag="DMO12_20009"
     CDS             1702..1845
                     /locus_tag="DMO12_RS18665"
                     /old_locus_tag="DMO12_20009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004786602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001125246.1"
                     /translation="MPKLKDIALGIIVAPLLIPIMLIASYQDKKALKKELDECQKEKDQ
                     AS"
                     /name="hypothetical protein"
     gene            complement(2027..2341)
                     /locus_tag="DMO12_RS18670"
                     /old_locus_tag="DMO12_20012"
     CDS             complement(2027..2341)
                     /locus_tag="DMO12_RS18670"
                     /old_locus_tag="DMO12_20012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005108843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000723215.1"
                     /translation="MKKILYFNFLAIILTYVSLLYQKNILVARIVVDKLEKVEVIAGGF
                     PLQFLIDGETSPVGSISINPLFIFIGMDQFVFLNFFIDYLFWVSILFAFSMIVKKYRIV
                     "
                     /name="hypothetical protein"
     gene            2460..3164
                     /locus_tag="DMO12_RS18675"
                     /old_locus_tag="DMO12_20015"
     CDS             2460..3164
                     /locus_tag="DMO12_RS18675"
                     /old_locus_tag="DMO12_20015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001067856.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_001067856.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFET"
                     /name="IS6-like element IS26 family transposase"
     gene            complement(3526..>3720)
                     /locus_tag="DMO12_RS19315"
                     /pseudo=""
     CDS             complement(3526..>3720)
                     /locus_tag="DMO12_RS19315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016658926.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            3745..4053
                     /locus_tag="DMO12_RS18680"
                     /old_locus_tag="DMO12_20018"
     CDS             3745..4053
                     /locus_tag="DMO12_RS18680"
                     /old_locus_tag="DMO12_20018"
                     /inference="COORDINATES: protein motif:HMM:NF023295.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction enzyme endonuclease
                     domain-containing protein"
                     /protein_id="WP_000796997.1"
                     /translation="MAEELNLTEYEYAFYSAVADNESARELMQKEILRELAVVLTDSIR
                     KNVTLDWTIKEAARAKLRVIVKRLLKKYGYPPDMALLATEPVLEQAEQLAEELASAT"
                     /name="type I restriction enzyme endonuclease
                     domain-containing protein"
     gene            complement(4258..5205)
                     /gene="repM"
                     /locus_tag="DMO12_RS18685"
                     /old_locus_tag="DMO12_20021"
     CDS             complement(4258..5205)
                     /gene="repM"
                     /locus_tag="DMO12_RS18685"
                     /old_locus_tag="DMO12_20021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000845976.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein RepM"
                     /protein_id="WP_000845976.1"
                     /translation="MKTELVVKDNALINASYNLELAEQRLILLSIVKARETGRGITSDS
                     RLEVHASDYMKQFNVEKSAAYEVLKSASESLFNRYFSYKEQRHDGTEFVVKSRWVSRVA
                     YAPNVAILEVTFAPDVVPLITRLEQHFTSYQLKQVSQLTSKYAIRLYEMLIAWRNVGKC
                     SFELINLRDSLGIASDEYKQMGHFKSRVLDASIAQINEYTDIKVTYEQQKNGRTISGFT
                     FKLKPKQVQQEITILDTKASLIPSDLTPNQRVTFASKLSKLQELGGKAEPGEEVEAFAK
                     RIELWLEDEKKLKMLTPFLYQVGFKKAKPKKVSQ"
                     /name="repM"
     gene            5630..6259
                     /locus_tag="DMO12_RS18690"
                     /old_locus_tag="DMO12_20024"
     CDS             5630..6259
                     /locus_tag="DMO12_RS18690"
                     /old_locus_tag="DMO12_20024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016658925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_000584713.1"
                     /translation="MIILIGSQKGGCGKSTIAINIAAYLAKHNKDIVLVDADPQQSSAN
                     WVKDRDDTDLPKVHCIQRYGDIKNTLKDLDSRYDYVVVDVAGHDSKELRTAMLAAHYLV
                     VPFRPSQFDLDTLPHLSEVIDQAQSFNEDLKPFGLLTLAPTNPSVSEVQQANEYLADFP
                     LFTALSSVIHDRKVYRDVTAEGKGVVESNNPKAIDEFDAFMKELLA"
                     /name="AAA family ATPase"
     gene            6256..6492
                     /locus_tag="DMO12_RS18695"
                     /old_locus_tag="DMO12_20027"
     CDS             6256..6492
                     /locus_tag="DMO12_RS18695"
                     /old_locus_tag="DMO12_20027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000592589.1"
                     /translation="MIKKRELAKPSPDMEAFINGANEETNQKLDPKAPRKFKTHTIPMN
                     EYEYQLLAELAEKYGQTHNGIIRFALKKLSEEN"
                     /name="hypothetical protein"
     gene            <6608..>6676
                     /locus_tag="DMO12_RS18700"
                     /pseudo=""
     CDS             <6608..>6676
                     /locus_tag="DMO12_RS18700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004889724.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /name="helix-turn-helix domain-containing protein"
     gene            6759..7184
                     /locus_tag="DMO12_RS18705"
                     /old_locus_tag="DMO12_20030"
     CDS             6759..7184
                     /locus_tag="DMO12_RS18705"
                     /old_locus_tag="DMO12_20030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001083446.1"
                     /translation="MNSDAVWTMTEKSRLKREDEVRMQELRHLFDLMDEREEEWQVTKT
                     TTLEKALKILSWCDLDVAPGLAELEMQQPIDIIEQHRKWLKAFRSAMPYLAKMLLVTDS
                     TLLIKLRCTLERYAEISYPNLLVVIQPKLQTLNFIKA"
                     /name="hypothetical protein"
     gene            7187..7435
                     /locus_tag="DMO12_RS18710"
                     /old_locus_tag="DMO12_20033"
     CDS             7187..7435
                     /locus_tag="DMO12_RS18710"
                     /old_locus_tag="DMO12_20033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002057569.1"
                     /GO_component="GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0097351 - toxin sequestering activity [Evidence IEA]"
                     /GO_process="GO:0045927 - positive regulation of growth
                     [Evidence IEA]; GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="WP_000192612.1"
                     /translation="MTQLIHARMTASITELKKSPMDTVLAGKGEPVAILNRNTPAFYCV
                     PADLYETMMEQLEDLELNKIADARANQKRIRVNIDDL"
                     /name="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
     gene            7425..7712
                     /locus_tag="DMO12_RS18715"
                     /old_locus_tag="DMO12_20036"
     CDS             7425..7712
                     /locus_tag="DMO12_RS18715"
                     /old_locus_tag="DMO12_20036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005021147.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_000221350.1"
                     /translation="MTYKLDFLEEALAEWNKLNPSIKQPLKKKLIKVLENPHIPKNKLS
                     GHPNRYKIKLRSVGYRLVYEVIDDEVVVIVIAVGRRENNAVYDEANSRHS"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            7984..9233
                     /locus_tag="DMO12_RS18720"
                     /old_locus_tag="DMO12_20039"
                     /pseudo=""
     CDS             7984..9233
                     /locus_tag="DMO12_RS18720"
                     /old_locus_tag="DMO12_20039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612089.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /name="IS3 family transposase"
     misc_feature    8273..8389
                     /locus_tag="DMO12_RS18720"
                     /old_locus_tag="DMO12_20039"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01497"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="AL1L pseudoknot; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /pseudo=""
                     /db_xref="RFAM:RF01497"
     gene            9870..10436
                     /locus_tag="DMO12_RS18725"
                     /old_locus_tag="DMO12_20045"
     CDS             9870..10436
                     /locus_tag="DMO12_RS18725"
                     /old_locus_tag="DMO12_20045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004282172.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000678311.1"
                     /translation="MKGQKVGYVRVSSVEQNTGRQLEGIEVDRIFVDRASGKNTDRPKF
                     QEMLNYVREGDRVIVHSMDRFARSLKDLVTEVDKLVKRGIAIQFVKENITFTAESTPMD
                     NLMLQMMGAFAQFEREIILERQKEGIKLASAQGKYKGRVHKLKPDQAEALRQAWKEGKY
                     PSKMALGKAFGISRQAVYRYLQVSE"
                     /name="recombinase family protein"
     gene            complement(10645..11163)
                     /locus_tag="DMO12_RS18730"
                     /old_locus_tag="DMO12_20048"
     CDS             complement(10645..11163)
                     /locus_tag="DMO12_RS18730"
                     /old_locus_tag="DMO12_20048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000447193.1"
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_000447193.1"
                     /translation="METFAEPVFSNDLLAKAENGDTSAQLELAEIYLYGHGVDSDENQA
                     EVWALKSAENGNVAAMFWLADGYVTYARLMEDDDKNDSLEHFQKAFKWFQKASENGHSE
                     SMVELADLYTRADSGIEVNINKAFELREKAAKLGNKKAMRSLSVMYRDGIGIPKNTDLA
                     QSWWDKSEN"
                     /name="tetratricopeptide repeat protein"
     gene            complement(<11414..11767)
                     /locus_tag="DMO12_RS18735"
                     /pseudo=""
     CDS             complement(<11414..11767)
                     /locus_tag="DMO12_RS18735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011959554.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
                     /name="IS1 family transposase"
     gene            11766..12985
                     /locus_tag="DMO12_RS18740"
                     /old_locus_tag="DMO12_20057"
     CDS             join(11766..12042,12042..12985)
                     /locus_tag="DMO12_RS18740"
                     /old_locus_tag="DMO12_20057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612089.1"
                     /ribosomal_slippage=""
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISAba2 family transposase"
                     /protein_id="WP_099527933.1"
                     /translation="MTKPKYTPEIRDRAVQLLIESEKDYPSNWAAITAIAPKIGCTPET
                     LRVWYLKHLDQQNPIKVQQASDQEKMKQMEREIKELKRANEILRKAAGFFRPGGARPPT
                     QIMVDFIHNNKDLYGVDAICRILPIAASTYYRTLDLADNPEHRAKRDLHDLHHAEQIKR
                     IWKESSGRYGVRKVWQKLKREGYIIARCTVARLMQKLGIQGVWRGKNKQTTHSRDDQKR
                     ADDLVKRNFSADHPDQLWVADFTYIQTNSGWVYTAFIIDVFSRAIVGWKVSTRMNTDMV
                     LDALEQALHDRGMPKNVIHHSDRGVQYLSIRYTNRLEAANLRASVGTTGDSYDNALAET
                     VNGLYKTEVIEYLKADWQGLADVQLATLNWVDWFNKERVHSALGYVSPFDFEAMYYDKI
                     NPLGQVA"
                     /name="IS3-like element ISAba2 family transposase"
     misc_feature    12041..12157
                     /locus_tag="DMO12_RS18740"
                     /old_locus_tag="DMO12_20057"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01497"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="AL1L pseudoknot; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /db_xref="RFAM:RF01497"
     gene            complement(<13019..13093)
                     /locus_tag="DMO12_RS18745"
                     /pseudo=""
     CDS             complement(<13019..13093)
                     /locus_tag="DMO12_RS18745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015586042.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
                     /name="IS1 family transposase"
     gene            13174..14016
                     /locus_tag="DMO12_RS18750"
                     /old_locus_tag="DMO12_20060"
     CDS             13174..14016
                     /locus_tag="DMO12_RS18750"
                     /old_locus_tag="DMO12_20060"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002002480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbapenem-hydrolyzing class D beta-lactamase
                     OXA-58"
                     /protein_id="WP_002002480.1"
                     /translation="MKLLKILSLVCLSISIGACAEHSMSRAKTSTIPQVNNSIIDQNVQ
                     ALFNEISADAVFVTYDGQNIKKYGTHLDRAKTAYIPASTFKIANALIGLENHKATSTEI
                     FKWDGKPRFFKAWDKDFTLGEAMQASTVPVYQELARRIGPSLMQSELQRIGYGNMQIGT
                     EVDQFWLKGPLTITPIQEVKFVYDLAQGQLPFKPEVQQQVKEMLYVERRGENRLYAKSG
                     WGMAVDPQVGWYVGFVEKADGQVVAFALNMQMKAGDDIALRKQLSLDVLDKLGVFHYL"
                     /name="carbapenem-hydrolyzing class D beta-lactamase
                     OXA-58"
     gene            14107..14813
                     /locus_tag="DMO12_RS18755"
                     /pseudo=""
     CDS             14107..14813
                     /locus_tag="DMO12_RS18755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015586042.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
                     /name="IS1 family transposase"
     gene            14987..>15271
                     /locus_tag="DMO12_RS18760"
                     /old_locus_tag="DMO12_20069"
                     /pseudo=""
     CDS             14987..>15271
                     /locus_tag="DMO12_RS18760"
                     /old_locus_tag="DMO12_20069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005046158.1"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family ligand binding domain-containing
                     protein"
                     /name="AraC family ligand binding domain-containing
                     protein"
     gene            complement(15323..16027)
                     /locus_tag="DMO12_RS18765"
                     /old_locus_tag="DMO12_20072"
     CDS             complement(15323..16027)
                     /locus_tag="DMO12_RS18765"
                     /old_locus_tag="DMO12_20072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001067856.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_001067856.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFET"
                     /name="IS6-like element IS26 family transposase"
     gene            16349..19903
                     /locus_tag="DMO12_RS18770"
                     /old_locus_tag="DMO12_20075"
     CDS             16349..19903
                     /locus_tag="DMO12_RS18770"
                     /old_locus_tag="DMO12_20075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid replication protein, CyRepA1 family"
                     /protein_id="WP_000477351.1"
                     /translation="MFKTNIHDFLLNLGYTTNNLPFQFVPEKQYRFPSMGKSAKNRAAS
                     IVLKANGTYLIYDHSCGASYVFNAERTSDKSKQDPAELEKLHIELEKQRKAEKQKKIIQ
                     FQIKASEAQQIWNKAKPCSAHPYMALAGIKPINARTLSIVKTSDGQTFINPLIIPLFDV
                     RTHELINLQFITADGTKRPLSGAQSKNYYFVIEGTEPTIFVEGYKDACNVFHATGRRVI
                     ACISAGKFKEVYPVLGKLCDVIIADNDNILKADPDDKTRKVVLSEQVVKGRGTGHRVAY
                     ELKAKFYLAPKLGSDAGSMTHEEIRNLLQQKLTSDIPAYDVWTQLKDEPCAIETKLLTD
                     ALSTEDNSHKCAVLAYQYIMRNLVHVPYKKNLIELRNEIEPFCVHRVHPVTLDNIILYA
                     HNRIEFMQTLGLDAVTIRDRKNHNLIKLDSLDHFSPNYKGVYLVKAPTGSGKTQKVGRP
                     FRDWCGQNGHPFLTIAHLRSLIREMASRLDTAHYEDEKKSIIEARKIGLDAALSQSIGS
                     LAVCLPSLANQLFKPFIKDCQHIFIDEISQLIETFNSDKLFNKTDIEYVYNLLKVIIKN
                     AECIIVADANINSKTLDFIESCRPNEQFTIVEVEPKDESKTVYLYNSFAELQSFMLQRV
                     MVENQNLWITCDSKSHVQALHAILRDLDVKSIAIVGNENIKKETAEFLSDPETESLKYQ
                     VVISTSAIASGVSIQHEQFIHDNGKGYFDCVVGFFTGSSIQPTDAYQMIGRVRYATDFH
                     IFADQSKRYTMNVLDILQGKQQASILEGKKAKITEFSLFKTELENIRETRRSNFANNLI
                     WILESKLFNIKRVQKFDASEHTEFFKHTKKAVKEAKRELIKTAYKINDETASRLQRKEF
                     LSEAEANALQAYKMRSKLGLDYVTELTDEHFDIDIGQLIRFSAFMGRYKPSNDKSKDLA
                     IRRYHEAMGKAYKLAFDGVELQPNAVFTETSAKALLQQIAKYKLVLASIGAIPTRFGVQ
                     SWKPSEYAVRDLNEVLKHIGVKSKYVRNPFKPRLKRKLSVEMPNNLYIRIEPSQQIMDE
                     YAYKIDPDNYLLMQQLCESVLKSATKQVEHENVQQLAEAVKRPDFVSSDDVKIDIQSVT
                     LVTHATEQQLAIQPSNDVVFIDVMKELMRSDLTLADFYRLKDYAEYLPKLHVSADSAQQ
                     VSELDLINSMISSRASIL"
                     /name="plasmid replication protein, CyRepA1 family"
     gene            complement(20137..20634)
                     /locus_tag="DMO12_RS18775"
                     /old_locus_tag="DMO12_20078"
     CDS             complement(20137..20634)
                     /locus_tag="DMO12_RS18775"
                     /old_locus_tag="DMO12_20078"
                     /inference="COORDINATES: protein motif:HMM:NF025323.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafO family toxin"
                     /protein_id="WP_000640864.1"
                     /translation="MIYVEISEELENDAEEMGISNELNFIADQFLIYKQASRNREHPAP
                     SRNVQERDQPASEYFGRDRFDKFSKNAQKEEIQHVHLRQEDSIWEDEEGYGYAQWHCTS
                     DSYLVYSYFKYKNDHYYYLIEFFGESAHSLYEKKTEKFIQCAKDFRFKKLKELENNNDK
                     LR"
                     /name="type II toxin-antitoxin system YafO family toxin"
     gene            complement(20637..20798)
                     /locus_tag="DMO12_RS18780"
                     /old_locus_tag="DMO12_20081"
     CDS             complement(20637..20798)
                     /locus_tag="DMO12_RS18780"
                     /old_locus_tag="DMO12_20081"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_153957353.1"
                     /translation="MVTKAVVIRRGKPRKVVAKPLNSEKQASFFRAVGMLTARGNEKLL
                     NSTHETQA"
                     /name="hypothetical protein"
     gene            21430..21723
                     /locus_tag="DMO12_RS18785"
                     /old_locus_tag="DMO12_20084"
     CDS             21430..21723
                     /locus_tag="DMO12_RS18785"
                     /old_locus_tag="DMO12_20084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000930833.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000930834.1"
                     /translation="MLNDALLTMRKYHRISQTELSQSLGISNSYLSEIESGKKKPTLEL
                     LDKYSEYFDIPVSSLMFFSENMDKRDTLSGKFRYFAGSKVIKLMNWLSENGK"
                     /name="helix-turn-helix transcriptional regulator"
     gene            21713..22615
                     /locus_tag="DMO12_RS18790"
                     /old_locus_tag="DMO12_20087"
     CDS             21713..22615
                     /locus_tag="DMO12_RS18790"
                     /old_locus_tag="DMO12_20087"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446053.1"
                     /GO_function="GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="reverse transcriptase family protein"
                     /protein_id="WP_000431810.1"
                     /translation="MENSQPSDYAKYVYELELLNSPLFHITSKKRLAILLCSSIKELNH
                     IVRSKNQMYQYFNENKTDDSGNIIKVRPIQNPHDRLKQIHSRIGKFLGNLKAPDYLHSK
                     RSKSAISNAKAHVGLKGHTLNIDITDFYPSTSKAKVQSFFGYTLQYPTDIAKYISEVCT
                     VNNCLPTGSPLSSALAFWANKSMFDEIYRMAKSRSITMTVYVDDISFTGKAVNQNFLNK
                     IIQIIEKYQHNIKQEKIKFFPENSIKFVTGVAIVNGSLQPAHRHFRDIRQLKKIDNNIQ
                     AALRLIGKNNYIKQIINHV"
                     /name="reverse transcriptase family protein"
     gene            complement(22656..22829)
                     /locus_tag="DMO12_RS18795"
                     /old_locus_tag="DMO12_20090"
     CDS             complement(22656..22829)
                     /locus_tag="DMO12_RS18795"
                     /old_locus_tag="DMO12_20090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001282484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001282484.1"
                     /translation="MSDNIIQLSKPCTLCENRQNVQLFAGLMLCGSCQENIRLTNPSMF
                     SANDEIEQKAQN"
                     /name="hypothetical protein"
     gene            complement(22829..23200)
                     /locus_tag="DMO12_RS18800"
                     /old_locus_tag="DMO12_20093"
     CDS             complement(22829..23200)
                     /locus_tag="DMO12_RS18800"
                     /old_locus_tag="DMO12_20093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000504218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000504218.1"
                     /translation="MGEKVKTYAVRLDPQVAEFYDQLANSEGIRTSKLFSKILTNDFQS
                     IAVKQQADRIEDLVNRLEKRIDDFEEDNNFSEKYYEDFSGLYFMMLWLLMKNGASKDEV
                     RMIQAKGYSYADDNYKRVK"
                     /name="hypothetical protein"
     gene            complement(23472..23726)
                     /locus_tag="DMO12_RS19320"
                     /old_locus_tag="DMO12_20096"
     CDS             complement(23472..23726)
                     /locus_tag="DMO12_RS19320"
                     /old_locus_tag="DMO12_20096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001014301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001014303.1"
                     /translation="MNGQKIDFLRFSKQGNKYFFPCKTKHRPYVTLANFPIQDPAHAGI
                     FLSHTTHLTMTPLKALQDKDFSDFLGSQKRVQKNGLFLE"
                     /name="hypothetical protein"
     ARG             13175..14013
                     /name="blaOXA-58"
                     /gene="blaOXA-58"
                     /gene_name="carbapenem-hydrolyzing class D beta-lactamase
                     OXA-58"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(2028..2341)
                     /name="ADC-8"
                     /gene="ADC-8"
                     /gene_name="ADC beta-lactamase without carbapenemase
                     activity"
                     /tool="rgi"
                     /drug_class="cephalosporin"
                     /identity="100.0"
                     /coverage="26.2"
     Typing          165..1114
                     /name="rep_cluster_1172"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          8316..8746
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="87.5"
                     /coverage="100.0"
                     /evalue="1.5600000000000002e-161"
     Typing          8743..9230
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="97.546"
                     /coverage="100.0"
                     /evalue="1.5600000000000002e-161"
     Typing          12084..12982
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 atatgtccac gtttaccttg caatatgtcc acgtttacct tgcaatatgt ccacgtttac
       61 cttgcaatat gtccacgttt accttgcaat atgtccacgt ttaccttgca ttagtacaca
      121 aataatatta acgtgtactt atacacaata aaaaatagtg gctatgagag atttagttgt
      181 aaaggacaat gccttaatca acgcaagcta taacttagac ttagtagaac aacgtttaat
      241 tttattggct attgttgaag caagggaaag tgggaaaggg attaatgcaa atgatccatt
      301 agaagttcat gcagatagtt atatcaatca atttggtgta caccgtaata cagcttatca
      361 agccttaaaa gatgcttgta aggatttatt cgcgcgtcaa tttagctatc aagagaaaaa
      421 agctaatggg aatatccgaa atgttatgag tcgttgggta tctcaaattg cttataacga
      481 caatgaagca actgtagact taatatttgc acctgctgtt gttcccttca taacccgact
      541 ggaagaacaa tttactaaat atgaattaca gcaagttagt agtcttagta gcgcttatgc
      601 cattcgctta tatgagcttc taattcagtg gcgaagcact ggtaaaaccc caaccataga
      661 actacaagaa tttagaaaga agttaggcgt tcttgataat gaatatttac ggatggctca
      721 tttaaaagag cgtgttttag agctttcaat taaacaaata aatgagcata cggatataac
      781 tgtaaaatat gaacagcata aaagaggacg ttctatttca ggattttctt ttacctttaa
      841 acagaagaag aaggatagcc catcaataga aagagatccg aacactttgg agcttttttc
      901 aaagatgacc gatgctcaac ggcatatgtt tgcaaataaa ctttcagaac tccctgaaat
      961 gggtcgctat tcacaaggaa cagaaagcta ccaacagttt gctgtacgta ttgctgagat
     1021 gctacaagat cccgctcaat tcaaagagct atacccatac ctaaaaaaag tgggatacat
     1081 gccatcaaat aaaaaggaca ccgtaaatgg ctaagttatc actaagtgaa gtatctaaaa
     1141 aatttcatgt ggatagatca accatttaca gagctgtacg taatggacgt ttatcacgct
     1201 ccagtgatgg acaattcgat ctagcagagg tcatacgatg ctttggagaa cctgagcaaa
     1261 catctcaaaa aattgaatca tctaagcaag aaggtgatga atctacaaaa aaacttattg
     1321 cccatttaga aaatgaagtc aaaaaatacc aagaacgtga agaacggtta atgcaacaaa
     1381 ttgaccgtat gcaaacactc attgagctga aaagtgttgc acctgccaca gcagcaccac
     1441 accaagatgc tacggcatgc gacaccaaga tgccacagca tgcgacaaca caacaagaca
     1501 ctgataacaa aaagaataat gaattaaata ttgcagaaaa tgtagcagtg ccacagcaag
     1561 aaactacggc ataccacacc caaacgctac agcatgccac gttgcaaagt gtggcagtgc
     1621 cacaacacaa aaaacgtggt ttatttggcc gtgtgctgaa tgccgtcttt gataatgact
     1681 gagcaataag ggtgaaagat catgccgaaa ctgaaagaca ttgccctggg aattattgta
     1741 gctccgctgc tgatcccgat catgctgatt gcatcgtacc aggataaaaa ggcgctgaag
     1801 aaagagctgg atgaatgcca aaaagaaaaa gaccaggcat cctgattatt caattgagct
     1861 aatcaaaagt gtggaacatt gatgaaataa tagcgtggaa cgtgaaaagt cataaaaaaa
     1921 gcccgaacag ggatgctcgg gctataaact agaaactaca gcgttgaatt ataaggataa
     1981 ttatacagca tttcgtataa ggtgtattat gttaatttta ggagatctat acaattctgt
     2041 actttttcac aatcatagaa aaagcaaata aaatacttac ccaaaataaa taatcaataa
     2101 aaaaattgag aaaaacaaat tgatccatgc cgatgaaaat aaataaagga ttgatactta
     2161 tacttccgac tggagaggtt tcaccatcta taaggaactg tagaggaaat cccccagcta
     2221 tgacttcaac tttttcaagc ttatctacaa ctatgcgagc aactaatata tttttttgat
     2281 aaagcaaaga tacataagtc aaaataatcg ctaagaaatt aaaatataat atttttttca
     2341 taactattct ttatctttta aattaattaa aaacagccaa taacataagc caggaaggca
     2401 ctgttgcaaa tagtcggtgg tgataaactt atcatcccct tttgctgatg gagctgcaca
     2461 tgaacccatt caaaggccgg cattttcagc gtgacatcat tctgtgggcc gtacgctggt
     2521 actgcaaata cggcatcagt taccgtgagc tgcaggagat gctggctgaa cgcggagtga
     2581 atgtcgatca ctccacgatt taccgctggg ttcagcgtta tgcgcctgaa atggaaaaac
     2641 ggctgcgctg gtactggcgt aacccttccg atctttgccc gtggcacatg gatgaaacct
     2701 acgtgaaggt caatggccgc tgggcgtatc tgtaccgggc cgtcgacagc cggggccgca
     2761 ctgtcgattt ttatctctcc tcccgtcgta acagcaaagc tgcataccgg tttctgggta
     2821 aaatcctcaa caacgtgaag aagtggcaga tcccgcgatt catcaacacg gataaagcgc
     2881 ccgcctatgg tcgcgcgctt gctctgctca aacgcgaagg ccggtgcccg tctgacgttg
     2941 aacaccgaca gattaagtac cggaacaacg tgattgaatg cgatcatggc aaactgaaac
     3001 ggataatcgg cgccacgctg ggatttaaat ccatgaagac ggcttacgcc accatcaaag
     3061 gtattgaggt gatgcgtgca ctacgcaaag gccaggcctc agcattttat tatggtgatc
     3121 ccctgggcga aatgcgcctg gtaagcagag tttttgaaac gtaaggcctt tgaataagac
     3181 aaaaggctgc ctcatcgcta actttgcaac agtgcccata aaaatacgtc agtgattttt
     3241 ttaactcagt aaaaattgat ataccaacct gaatccactt cttgctgctt tggcatggat
     3301 taattttaga attatttcaa tgtcaggttt tgccatttaa atcaaggaca tgactgtcga
     3361 gagcttaggt tttcgctttg ctcaatccga ggggaagtag ggatttagct ttgttacata
     3421 aatagtttaa aatatgattt tataaagctt aacttaaatt agaactaaaa caaaactaaa
     3481 gtaaaaccaa attagtttta cttaacaact aattttattt cactattaaa cttctaatcc
     3541 caaatctttt agaacaccag catactttct aacattttga acatcctcta attcaattag
     3601 aagccttttt tctagatcag catagctttc ccctactgca gctttttggc ttgcaaatgg
     3661 gtcatggtga gctagcttgt tggcaaaaaa ttgaatctgc ttatccgtta gcttctggct
     3721 aaggcaatcc aagaatcaga caaaatggca gaggaactca acctgactga atatgaatat
     3781 gccttctact ctgctgtcgc ggataacgag agtgctcggg agttaatgca gaaggagatc
     3841 ctacgcgaac tcgctgttgt tctgactgat tccattcgta agaatgtgac cttggattgg
     3901 acgatcaaag aagcagccag ggcgaaactg agagttattg tgaagcgtct actcaagaag
     3961 tatggctacc cacctgatat ggctttactg gctactgagc ctgtactcga acaggcagaa
     4021 cagttagctg aggaattagc atctgctaca taaggtttta cgctccattt gataaaacac
     4081 ccactcaatt tgagtgggtg tctcgagcca taaacaactt ttagcagtag ctttggacat
     4141 catcgagcat tattatcata acctacctac atgattgctt tataggctaa aaaccacata
     4201 attgacaact aaagaacaac taaattagtt tcaaataaga actagaattg agaagttcta
     4261 ctgagatact ttctttggtt tagctttttt aaatcctact tgatagagaa atggagtaag
     4321 catcttcaat tttttttcat cctctagcca taactcaatt cgttttgcaa atgcctctac
     4381 ttcctcacca ggttctgctt ttcctcctaa ttcttggagt tttgataatt tactagcaaa
     4441 agtaacacgt tggtttggag tcagatcaga aggaattaac gatgcttttg tatctaggat
     4501 ggtaatttct tgttgtactt gtttaggctt taacttgaag gtgaatccac taatagttcg
     4561 accattcttc tgttgttcat aagtcacttt gatgtctgtg tactcattaa tttgagcaat
     4621 tgatgcgtct agaacacgac ttttgaaatg ccccatttgc ttatactcat cagatgcaat
     4681 ccctaagcta tctctcaaat tgatgagctc aaaagaacat tttcctacat tacgccatgc
     4741 aatcagcatc tcatataatc taatagcgta tttacttgta agttgagaaa cttgctttag
     4801 ttggtagcta gtgaaatgct gctctaatcg agtaattaat ggcacaacat ctggtgcaaa
     4861 agttacttcc aatatagcta cattgggagc atatgctaca cgactgaccc aacgtgattt
     4921 aaccacaaat tccgttccat catgtctttg ttccttatag gaaaagtaac gattaaagag
     4981 actttctgat gcgctcttta atacttcata agctgcactt ttctccacgt taaactgctt
     5041 catatagtca ctagcatgaa cctctaaacg actgtcagaa gtaatccctc gccctgtttc
     5101 ccgagctttt acaatggaaa gtaaaattag tctttgttct gcaagctcta aattataaga
     5161 agcattaata agagcattat ctttaactac tagttcagtt ttcatttttc aatttactag
     5221 cacaagtaaa atcacactat atatcacagc ttatttaatc acaacaaaca ttaatgtgat
     5281 taaataaacg gaatctgtga ttgaatggaa tggaatctgt gattgaatgg aatggaatct
     5341 gtgattgaat ggaatggaat ctgtgattga atgacctctg tatgccttgc tgtcactgca
     5401 ttacagccag cttaaaagca ttaaaagcat taaaagttaa taaaagcctt ttttcatttt
     5461 ctaaaactta aaaagtaaga atgtattcct atcaatttga taatggaata tgagctaata
     5521 gttgatacat tttggaattt gtgaaaagta aaaattgtca ttcattgtct ttacatatat
     5581 ctaatttgat tacatactag ttgcaaatta gttataagtt acaagtaaaa tgattatatt
     5641 gattggaagc caaaaaggtg gatgtggtaa atcaacaata gccatcaaca ttgcagcata
     5701 tcttgctaaa cataacaaag acatcgtatt agttgatgct gatcctcagc aaagttcagc
     5761 taactgggtt aaagacaggg atgacactga cttacctaag gttcattgta ttcaacgcta
     5821 tggcgatatc aagaacacct tgaaagactt ggacagtcgt tatgactatg ttgttgttga
     5881 tgttgcaggt cacgatagta aagagctgag aacagcaatg cttgcagctc attaccttgt
     5941 agtaccgttt agaccatctc aattcgatct agatacccta cctcatctct ctgaagtcat
     6001 agatcaagcc cagtcattca atgaagactt gaaacctttt ggcttactaa cattggcacc
     6061 tacaaatcca tcagtatctg aagtacagca agcaaacgag tatctcgctg acttcccatt
     6121 gttcacagcc ttgtcatcag taatccatga tcgcaaagtt taccgggatg ttactgctga
     6181 aggtaaaggt gttgttgaat ccaataatcc aaaagcaata gacgagtttg acgcttttat
     6241 gaaggagctt ttagcatgat taagaaaaga gaattggcaa aaccttctcc tgacatggaa
     6301 gccttcatca atggtgctaa tgaggagact aatcaaaaac tagatccgaa agcacctaga
     6361 aaatttaaga cgcatacgat tccaatgaac gaatatgagt atcagctatt ggctgagtta
     6421 gctgaaaaat atggtcaaac ccataatgga attatcagat ttgctctgaa gaaacttagt
     6481 gaagaaaatt aactaatttg aaactaatat aaaactaatt tagtttttaa ttggttgtga
     6541 tttgagtgta gaaaagccct taatgattaa gggctttttt gtatctgtta gacctatatc
     6601 atgtcggaac atgaccaagg atgaaatagc taaagcagtt ggttgtggag tttctaccgt
     6661 ttatcgagta gcgaaaagta ctcattatgg tttttttaat agcatcttta aatgtgcttc
     6721 taggaatgct atagtcatag cgttgaatag gagaatctat gaattctgat gctgtttgga
     6781 ctatgactga aaaatctcgt ttgaaacgag aggatgaagt tcgtatgcag gaactcagac
     6841 atctattcga tttgatggat gaaagagagg aagagtggca ggtaactaaa actactacat
     6901 tagaaaaagc tctaaagata ctttcatggt gtgatcttga cgtagctcct gggttagctg
     6961 agctagagat gcaacaacct atagatatta ttgagcaaca tcgtaagtgg ttaaaggcat
     7021 ttcgttcagc gatgccttat cttgcaaaga tgctcctcgt cactgattca accctactta
     7081 tcaaattaag atgcacatta gagaggtatg ctgagattag ctacccgaac ctacttgtag
     7141 tgattcaacc caaactgcaa acacttaact ttataaaggc ctaactatga ctcaattaat
     7201 ccatgcacga atgactgcaa gtattactga actcaaaaag agtccgatgg atacagtgtt
     7261 agcaggtaaa ggtgaacctg tagcgatcct taatcgtaat acaccagcgt tttactgtgt
     7321 tccggctgat ttgtatgaaa ccatgatgga acaactggaa gacctggaac tcaacaaaat
     7381 tgcagatgct cgtgcgaatc aaaaacgcat tcgagtaaat attgatgacc tataagttag
     7441 actttttaga agaagcatta gcagaatgga ataagcttaa tccaagtatt aagcaaccat
     7501 tgaagaagaa actgatcaag gtactagaga atcctcacat tcccaagaat aagctctcag
     7561 gacatcctaa ccgctacaag atcaaacttc gcagtgttgg ttatcgtttg gtttatgaag
     7621 tgattgatga tgaggttgtt gtcatcgtca ttgccgtagg cagacgtgaa aacaatgctg
     7681 tgtatgatga agccaactct cgacattcat aagtaattga ttgcattaag caggaattct
     7741 ttcattaggg aattcctgct taatgcacat atggaatata tcttacagat tttagttatt
     7801 ttttttaata tttaattgaa actaaattaa aactaattag aaactataat tgtgcattta
     7861 ataggggatc atctctattt cacaacccag agttgatccc acttaaagta gttatgcgtc
     7921 aacttatctc tggtgaaccg taccgggttt gtcggagagt caatattctg agagactatc
     7981 ccgatgacaa aattaaaata tacccctgaa atcagagaaa gagcggttca attattgatt
     8041 gaatctgaaa aagattatcc atcgaattgg gctgcgatca ccgctattgc tccctgagca
     8101 gtatactgcg caagggttgt actactgaaa cactacgtgt ttggtatcaa aaatatttag
     8161 ataaacaaaa tccagttaaa gtacagcagc tttcagacca agaacgtatc aaacaactcg
     8221 aacgcgaaaa taaagaactg caacgcgcca atgagattct acgtaaagca gccgcttttt
     8281 tcgcccaggc ggagctcgac cgcccacaca aataatggtg gattttatcc ataacaataa
     8341 agagctgtac ggagtcgagg caatttgtag aattttaccg atcgcacctt caacctatta
     8401 ccagactcta gatctctgcg atgagaagca ttgcttcgca agggaacatc gagcgaaacg
     8461 agatttacat gacttgcatc atgctgagga gattaaacga atttggaaag aaagttcagg
     8521 tcgatacggt gtgcgtaagg tctggcaaca actgaaacgt gaaggctata ttattgcacg
     8581 ctgtactgtt gctcgattaa tgaaaaagct aggtatacaa ggtgtttggc gaggtaagaa
     8641 caaacaaacc acccgtagcc gagatgacca aaaacgagca gatgatttag tgaaacgtaa
     8701 ttttactgct gatcatcctg accaactgtg ggtcagtgac tttaccgtat attcaaacaa
     8761 attcaggctg ggtctatacc gcctttatta ttgatgtgtt ttcacgagca attgttggct
     8821 ggaaagtatc tacacggatg aatacagata tggtgctcga tgcattggag caagcattgc
     8881 atgatcgcgg catgccaaag aatgtgattc atcattccga cagaggtgtg caatatcttt
     8941 ccattcgcta taccaatcgt ttagaagcag caaatttacg agcatcagtc ggtacgactg
     9001 gtgattcata cgataatgct ttggctgaaa cggtgaatgg cttatacaaa acagaggtga
     9061 ttgaatatct aaaagcagat tggcaaggtt tagcagatgt acaacttgcg acactaaact
     9121 gggtagattg gttcaataaa aagcgtgtac acagtgcact gggttatgta tcgccttttg
     9181 agtttgaagc aatgtactat gataagatta acccgttagg tcaggtggcc taacttaaat
     9241 aaaaaagtct ccgacaaacc cggtacggtt catggtcatc tttcatgtcc tattgggtag
     9301 catacttgct ccaagtgcca gttttgtctt gctaaactta tattgaatct tttctagtgt
     9361 ttccattaaa actgaaggta tttgcaaaat tagccatgta atttaattat tgatgggcta
     9421 ttggaagaag gaatgagtga tagactatga acaagaatgc gtagtcattt tattcagtat
     9481 tttgtaattt aactaaatga aatttattga attttaatta ttaattaaaa aaattaaaac
     9541 gcccaatttg aaaaactggg cgcttcacta atggtaataa tcattaccat caaccactag
     9601 agaacacaaa ccatggttca gttttgtgtt ttataaacat actttgtgta tgtgagtttg
     9661 taaatgattt tttgctcaga gatttaaaaa tcaaagtatc ttcttattga tatttgtaat
     9721 attagactat accctaaagt tacaatctga aagttcatga aattatgtat catttaaatg
     9781 atttttaatc ataagtaaca tgtaacttta gtgttaaaga tttataattt acaaaattgt
     9841 tcatttttat ccaattgggg cgtgaaaaag tgaaaggcca aaaagtaggg tatgtccgtg
     9901 taagttctgt cgagcaaaac actggacgtc aacttgaagg aattgaggtc gaccggattt
     9961 ttgttgaccg tgcttcaggt aaaaatactg accgacctaa atttcaggaa atgttgaact
    10021 atgtgcggga aggggacagg gtgattgtac attcaatgga tcgttttgcg cgaagcctaa
    10081 aagatttggt cactgaagta gataaactgg tcaaacgagg gatcgccatc caatttgtaa
    10141 aagaaaatat tacttttaca gccgaatcca ccccgatgga taatttgatg cttcaaatga
    10201 tgggtgcttt tgcacagttc gaacgtgaga tcattttaga gcggcaaaag gaaggaataa
    10261 aactcgcctc tgctcagggg aagtacaaag gtcgggtgca taaactaaag cctgaccaag
    10321 ctgaagcttt acgacaagca tggaaggagg ggaagtatcc atcgaaaatg gcattaggga
    10381 aagcttttgg gattagtcgt caggcggtat accgatattt acaagttagt gaatagctta
    10441 ttaggattag caactaaatt tagtttaact tataaaaatc atgaaacact gttcgaattt
    10501 taagcgtgga acatgaataa tcaataaaaa gccgctctgg tgccctatat tccagaacgg
    10561 cttgctttaa gataatgata tttaaagaga aatatcaagc attacgtata aggtgtatta
    10621 tgttaatttt aggaaatatt aaaactaatt ttcagactta tcccaccaac tttgagctaa
    10681 atcagtattt ttaggaatac ctataccatc acgatacata acggaaagac ttcgcattgc
    10741 tttcttatta cctaactttg cagccttttc acgaagttca aaagctttat taatattaac
    10801 ttctattccg ctatctgcac gagtatatag atcagctaac tcaaccattg attcagaatg
    10861 gccattttct gaggctttct gaaaccactt aaaagctttt tggaaatgtt ctaaagaatc
    10921 gtttttgtca tcatcttcca ttaatctagc ataagtaaca tatccatcag ctaaccaaaa
    10981 cattgctgct acatttccat tttctgctga tttaagagcc caaacttcag cttgattttc
    11041 atctgaatca acaccatgac catatagata aatctcggct aattctaact gagcagaagt
    11101 atctccattt tctgctttcg ctaataaatc attagaaaaa acaggttctg caaatgtttc
    11161 cattgaaagg caaactccta aagccataaa aatatttgtt aatttattca atttttaacc
    11221 tttaaactaa actgttaggc ttgtatattt ttatatcata cctaaaagaa aactctaaaa
    11281 ttagagtatg tcttatctct atttaacata atggctgtta tacgaaacga gagtgttaga
    11341 acccatttaa agtgtctata ttctcaccaa taaaaatgtc cggtttctcc gaggtaaaat
    11401 atgacttttg aacaaaaata agccattgtt tattcttttt atttccaaca aaattccaga
    11461 actcatctac ttcgagagat tcataatgac tttgctgagg ctgaatttca taggttgatt
    11521 cagttaaagt acgtaaaact ttaccgatac tgatgcgctc aacttcagca atatctcgta
    11581 taccgctgcc tctgaccatc aactgtaata ttttacgagt aatacctgac ttacatccta
    11641 gatagctcag tgcatgatca ccaataaact gacgtttaca gtctttgcac tgatagtttt
    11701 gtttcccatc tactttgaac cgtaccgggt ttgtcggaga ccaactttct tgagagaatg
    11761 tcccgatgac aaaaccaaaa tatacccctg aaatccgaga tagagcggtt caattattga
    11821 ttgaatccga aaaagattat ccatcgaatt gggctgcaat cactgctatt gctcccaaga
    11881 taggttgtac tcctgaaaca ctgcgtgttt ggtatttaaa acatctcgat caacaaaatc
    11941 ctatcaaagt acaacaggca tcagatcaag aaaaaatgaa gcagatggaa cgtgaaatca
    12001 aagaattaaa gcgtgccaat gaaattctac gtaaagcagc tgcttttttc gcccaggcgg
    12061 agctcgaccg cccacacaaa taatggtgga tttcatccat aacaataaag acttatatgg
    12121 tgttgatgcg atttgtagga ttttaccgat cgcagcttca acctattacc gaactttaga
    12181 tctcgcggac aatccagaac atcgagcgaa gcgagattta catgacttgc atcatgctga
    12241 acaaattaaa cgaatttgga aggaaagttc aggtcgatat ggtgtacgta aagtttggca
    12301 aaaactgaaa cgtgaaggct atattattgc acgctgtaca gttgctcgat tgatgcaaaa
    12361 gctaggtata caaggtgttt ggcgaggtaa gaataaacaa actacccata gccgagatga
    12421 tcaaaaacga gcagatgact tggtgaaacg caattttagt gctgatcacc ctgaccagct
    12481 gtgggtcgct gactttacgt atattcaaac aaattcaggc tgggtctata ccgcctttat
    12541 tattgatgtg ttctcgcgag caattgttgg atggaaagta tcaacacgga tgaatacaga
    12601 catggtgctc gatgcactgg agcaagcatt gcatgatcga ggcatgccaa agaacgtgat
    12661 tcatcatagt gacagaggtg tgcaatatct ttccattcgt tataccaatc gtttagaagc
    12721 agcaaattta cgagcatcag tcggtacgac cggtgattca tacgataatg ctttggctga
    12781 aacggtgaat ggcttataca aaacagaggt gattgaatat ttaaaagcgg attggcaagg
    12841 tttagcggat gtacaacttg cgacattaaa ttgggtagat tggttcaata aagagcgtgt
    12901 acatagtgca ctaggttatg tgtcaccttt tgattttgaa gcaatgtact atgataaaat
    12961 taacccgtta ggtcaggtgg cctaacttaa ataaaaagtc tccgacaaac ccggtacggt
    13021 tcactttgat accatttttc tttatactat cactgaggca ggttggacat ttgattgcta
    13081 gagttatttg catttctcta ttttatcaaa atccaatcgg ctttttcttc agcatacttt
    13141 ttgaaacact accaaatttt aaagttgtat atcatgaaat tattaaaaat attgagttta
    13201 gtttgcttaa gcataagtat tggggcttgt gctgagcata gtatgagtcg agcaaaaaca
    13261 agtacaattc cacaagtgaa taactcaatc atcgatcaga atgttcaagc gctttttaat
    13321 gaaatctcag ctgatgctgt gtttgtcaca tatgatggtc aaaatattaa aaaatatggc
    13381 acgcatttag accgagcaaa aacagcttat attcctgcat ctacatttaa aattgccaat
    13441 gcactaattg gtttagaaaa tcataaagca acatctacag aaatatttaa gtgggatgga
    13501 aagccacgtt tttttaaagc atgggacaaa gattttactt tgggcgaagc catgcaagca
    13561 tctacagtgc ctgtatatca agaattggca cgtcgtattg gtccaagctt aatgcaaagt
    13621 gaattgcaac gtattggtta tggcaatatg caaataggca cggaagttga tcaattttgg
    13681 ttgaaagggc ctttgacaat tacacctata caagaagtaa agtttgtgta tgatttagcc
    13741 caagggcaat tgccttttaa acctgaagtt cagcaacaag tgaaagagat gttgtatgta
    13801 gagcgcagag gggagaatcg tctatatgct aaaagtggct ggggaatggc tgtagacccg
    13861 caagtgggtt ggtatgtggg ttttgttgaa aaggcagatg ggcaagtggt ggcatttgct
    13921 ttaaatatgc aaatgaaagc tggtgatgat attgctctac gtaaacaatt gtctttagat
    13981 gtgctagata agttgggtgt ttttcattat ttataagaat tagaagtttg aggttaatct
    14041 atttttggta gtgtttcaaa aagtatgctg aagaaaaagc cgattggatt ttgataaaat
    14101 agagaaatgc aaataactct agcaatcaaa tgtccaacct gcctcagtga tagtataaag
    14161 aaaaatggta tcaaagtaga tgggaaacaa aactatcagt gcaaagactg taaacgtcag
    14221 tttattggtg atcatgcact gagctatcta ggatgtaagt caggtattac tcgtaaaata
    14281 ttacagttga tggtcagagg cagcggtata cgagatattg ctgaagttga gcgcatcagt
    14341 atcggtaaag ttttacgtac tttaactgaa tcaacctatg aaattcagcc tcagcaaagt
    14401 cattatgaat ctctcgaagt agatgagttc tggaattttg ttggaaataa aaagaataaa
    14461 caatggctta tttacgccta tcatcgagaa acaggtgaaa ttgttgctta tgtttggggt
    14521 aaacgagatt tagctacagt ctaacaattg aagacaaagc ttaaacaatt agatattcac
    14581 tacacccgaa ttgcaagtga tcattgggac agtttcatca ctgcttttaa aaatggtaag
    14641 caaagtattg gtaaattttt tactgtaggt attgaaggca ataattgcaa aataaggcat
    14701 agaattaggc gtagcttcag aagaagctgt aatttttcaa aaaagcttga aaaccatttt
    14761 aaagcttttg atttagcctt cttttctttt acatcaataa tggcttcatt taaaggcagc
    14821 atactttttg aagcaccacc aaaattttat gttaagtaga gactaaaaat gcccttgatt
    14881 aagggcttac aagggcattt tgtataaggt gtattatgtt aattttagaa tttcttcatt
    14941 agataatttt tgataagcta aatccattag gactaattaa gtaaatatga gcaattgggt
    15001 caatgtcaca caggataagt ctacaggtat agaactaatt catgcccact tcaaaggctt
    15061 tgcatacgat cctcatctac actcaagtta tcttataggg gtaacagagt taggacatca
    15121 acaattcaat tgtagaaaaa aaattattga tagctatcaa ggtcaaactt tcatgcttga
    15181 acctgaagaa gttcatgatg gtaatgcacc agatcctctc ggcttcactt ataaaatgat
    15241 gcatttagat ccagcatggt taaaaaaaag ggcactgttg caaagttagc gatgaggcag
    15301 ccttttgtct tattcaaagg ccttacgttt caaaaactct gcttaccagg cgcatttcgc
    15361 ccaggggatc accataataa aatgctgagg cctggccttt gcgtagtgca cgcatcacct
    15421 caataccttt gatggtggcg taagccgtct tcatggattt aaatcccagc gtggcgccga
    15481 ttatccgttt cagtttgcca tgatcgcatt caatcacgtt gttccggtac ttaatctgtc
    15541 ggtgttcaac gtcagacggg caccggcctt cgcgtttgag cagagcaagc gcgcgaccat
    15601 aggcgggcgc tttatccgtg ttgatgaatc gcgggatctg ccacttcttc acgttgttga
    15661 ggattttacc cagaaaccgg tatgcagctt tgctgttacg acgggaggag agataaaaat
    15721 cgacagtgcg gccccggctg tcgacggccc ggtacagata cgcccagcgg ccattgacct
    15781 tcacgtaggt ttcatccatg tgccacgggc aaagatcgga agggttacgc cagtaccagc
    15841 gcagccgttt ttccatttca ggcgcataac gctgaaccca gcggtaaatc gtggagtgat
    15901 cgacattcac tccgcgttca gccagcatct cctgcagctc acggtaactg atgccgtatt
    15961 tgcagtacca gcgtacggcc cacagaatga tgtcacgctg aaaatgccgg cctttgaatg
    16021 ggttcatgtg cagctccatc agcaaaaggg gatgataagt ttatcaccac cgactatttg
    16081 caacagtgcc tttttatgtc agtgatcaaa cttttttttc aaaatctcaa cttttggaaa
    16141 atcatttttt tttatttgtt aatgtccgtt actgagtaca cgtcgaggac atatagctga
    16201 ttacttaatg aatagtgagt gagctataga cctgactgta ttccaaaata ttgcttcaga
    16261 agttgaagtc tcataaataa aaaaccccaa tagctaaatc tcgtggcggg actagctatt
    16321 agggttagaa ttacaggtac attgtacaat gttcaaaaca aatatacacg attttttgtt
    16381 aaatctaggc tacacaacta acaatttacc gtttcagttt gtaccagaga agcaatatcg
    16441 ctttcctagt atggggaaaa gtgccaaaaa ccgtgcagcg tcaattgttt tgaaagccaa
    16501 tggcacgtat ttaatttatg accattcatg cggtgcgagc tatgtcttca atgctgaacg
    16561 gacttcagac aaaagcaagc aagatccagc cgagcttgaa aagctacata ttgaattaga
    16621 aaagcagcgt aaagctgaaa aacaaaagaa aataattcaa ttccaaatca aagcaagtga
    16681 agctcaacag atatggaata aagccaaacc gtgctcggcg catccctata tggcattggc
    16741 tggtatcaag ccgataaatg caaggactct atcaatcgtt aagacgtcag atggtcagac
    16801 gttcattaat ccgctcatta ttccgttatt tgatgttcgt acgcatgaac ttataaacct
    16861 tcaattcatc acagccgatg gaacaaaacg cccgctatct ggtgctcaga gcaaaaacta
    16921 ttattttgtg attgaaggta cagagccaac catatttgtt gaaggctaca aagatgcttg
    16981 caatgtgttc cacgcaactg gtagacgagt tatagcatgt atttcggctg ggaaattcaa
    17041 agaagtttat cccgtacttg gaaagctttg cgatgtaatc attgctgata atgacaatat
    17101 tctgaaagca gatccggacg ataaaacccg caaagtcgta ttgtctgagc aagttgtaaa
    17161 gggtcgtggt actggtcaca gagtagcgta tgaactgaaa gcgaagttct atcttgcacc
    17221 taaattgggt tctgatgctg gcagtatgac gcatgaagaa attagaaatt tactgcaaca
    17281 aaaactgact tcagacattc cagcttatga tgtttggacg cagttaaaag acgagccttg
    17341 cgctattgaa acaaaacttt tgaccgatgc tttgagcacc gaagataata gccataaatg
    17401 cgctgtatta gcttatcagt acatcatgcg caacttggtg catgttccat ataagaaaaa
    17461 tttaatcgaa cttcgaaacg aaatagaacc gttctgtgtg catcgtgttc atcctgtcac
    17521 tttagacaat attattctct atgctcacaa cagaattgag ttcatgcaga cgcttggttt
    17581 ggatgctgtc actattcggg accgaaaaaa tcacaacttg attaaattgg attctttgga
    17641 ccatttcagc ccgaactata aaggtgtgta tttggtgaaa gcgccaacag gatcaggaaa
    17701 aacgcaaaaa gtaggacgtc cgttccgcga ttggtgcggt cagaatgggc atccattttt
    17761 aaccattgca catttgcgaa gcctaatccg tgaaatggcg tcacgcttgg acacggcaca
    17821 ttatgaggat gagaaaaaaa gcatcattga agcgcgcaaa attggtttgg atgctgcttt
    17881 aagtcaatcc atcggatctc tggctgtatg cctgccaagt ctagccaatc agctatttaa
    17941 gcctttcata aaggactgtc agcacatttt tattgatgag atcagccaat taattgaaac
    18001 cttcaacagc gacaagttat tcaataaaac cgacattgaa tacgtttata acttgctgaa
    18061 ggtcatcatt aaaaatgcag agtgcatcat tgttgcagat gccaacatta actcaaaaac
    18121 attggatttt atcgagtcgt gccgaccaaa cgagcaattc actatcgttg aagtagaacc
    18181 caaagacgaa agtaagacag tgtacctgta taacagtttt gctgaattac agagttttat
    18241 gctgcaacgt gtcatggtcg aaaatcaaaa tttatggatt acgtgcgatt ccaaaagtca
    18301 tgtgcaggca cttcacgcca ttctcagaga tttggatgtt aaaagcattg cgattgtcgg
    18361 aaatgaaaac attaaaaaag aaacagcgga atttcttagc gatcctgaaa ccgagtcact
    18421 aaaatatcag gttgtaatct ctacaagtgc gatcgcttct ggtgtatcca ttcagcatga
    18481 gcaattcatt cacgacaatg gaaaagggta ttttgactgc gttgttggat tttttactgg
    18541 gtcgagtatt caaccgactg acgcatatca aatgatcggc cgtgtgcgtt acgctactga
    18601 cttccacatt tttgccgatc aaagcaaacg ctatactatg aatgtgttgg acattctaca
    18661 agggaaacag caagcgagta ttctggaagg gaaaaaagca aaaatcacgg agttttcact
    18721 atttaaaact gaacttgaaa atatccgtga aacccgtcgt tctaatttcg caaataactt
    18781 gatatggata cttgaaagca agctattcaa cattaagcga gtgcaaaaat tcgatgcttc
    18841 agaacatact gaatttttta aacatactaa aaaagcagtc aaagaagcca agcgagagct
    18901 gatcaaaact gcatacaaga tcaatgatga aactgcatcc agacttcagc gcaaagagtt
    18961 tttatctgaa gctgaagcca acgcgctgca agcatacaaa atgcggtcta agctcggtct
    19021 tgattacgtt acagaattaa ctgatgaaca ctttgatatt gatataggtc aattgatacg
    19081 attcagtgct tttatgggtc gatataagcc aagtaacgat aagagtaagg atttagcgat
    19141 tagacgctac catgaggcga tggggaaagc atacaagctg gcatttgatg gcgtggagct
    19201 acaacccaat gcggtgttta ctgaaacaag tgcgaaggca ctgcttcaac agattgcaaa
    19261 atacaaactt gtacttgcgt cgattggtgc aattccgact cgttttggtg tgcagtcgtg
    19321 gaaaccttcc gaatatgcag tgcgagattt gaacgaagtt ttgaagcata taggagttaa
    19381 atccaaatat gttagaaatc cattcaagcc gcgtttgaaa agaaaattaa gtgttgagat
    19441 gcccaataat ctatatataa gaatagagcc atctcaacag ataatggatg aatacgctta
    19501 taaaattgat cctgataatt atttgctgat gcagcaactc tgcgagtctg tcttgaagtc
    19561 agcgaccaaa caggttgagc atgaaaacgt gcagcaactt gctgaagctg ttaaacgtcc
    19621 tgatttcgtt tcatcggatg atgtaaagat tgatattcag tcagtaacac tggttactca
    19681 tgcaactgag cagcagcttg cgatccagcc aagcaatgat gtcgtattca ttgatgtgat
    19741 gaaagaactg atgcgctcgg acttaactct tgctgatttt tatcgcttga aagattacgc
    19801 agagtattta ccgaaactgc acgtttctgc tgacagtgct caacaggtat cagagttgga
    19861 tttaatcaat tcaatgatca gtagtagggc gtcgatttta tagcctaagc actaattctt
    19921 aggctatttt ggcgatcaag gctagaaaga cattattgat ataatagagc tctttcataa
    19981 atcaaaagtg atcacatttt ggttaatctt tacaccataa attgttgagc attcgtgcat
    20041 aatttaagga tgaaatacat cgattcaaag cagctttctg aaactgctta ataaatggct
    20101 tgagcaacaa gacgaattaa tttaccgtct cggggattac cttagtttat cgttattatt
    20161 ctctaattct tttaatttct tgaatctaaa atcttttgca cattgaataa atttctcagt
    20221 ctttttttca tataaagaat gagcagattc accaaaaaac tctataagat aataataatg
    20281 atcattttta tacttaaagt aagaataaac taaataactg tcactggtac agtgccactg
    20341 agcatagcca tatccttctt catcttccca aatactatct tcttgtctca aatgtacatg
    20401 ctgaatttct tctttttgag cattttttga aaacttatca aatctatctc ttccaaaata
    20461 ttcagatgca ggttgatctc tttcttgaac atttctagat ggagcaggat gttctctgtt
    20521 tcggctagct tgcttgtata taagaaattg atcagcaata aaatttaatt cattgctgat
    20581 tcccatttct tcagcatcat tttctaattc ttcagaaatc tctacataaa tcatttttat
    20641 gcttgagttt catgagtaga atttaataat ttctcattac ctctagctgt tagcatacct
    20701 accgctctaa agaaactagc ttgcttctca ctatttaaag gtttggcaac aacttttcgt
    20761 ggttttccac gacggataac tactgcttta gttaccatat tgaatctcct ttagatccat
    20821 aaaagttatt tcatatggaa tatatactag cataaatcat taccagttca ctcttattat
    20881 tttttcgcta ttagcgaaat aatatttgct aatagctaaa aaaaatgtat gatgaataag
    20941 ttacttcttg ttggataatc acccattttt gttatttgag tatttaaata ctcggaggtt
    21001 taaccacctc aaatttcggg gggatatggc tcttgatgac atgtagagat ctcaatgatc
    21061 gatatgcggt aagactataa ttccatcgat atgagtgcca cacgcaatgg agcgtgtggc
    21121 actttttgaa gagtcaagtg ctgaacacca gagtattttt cttcctagcg taaatggggc
    21181 caattttggt cgttaaggaa gattcaaatg aaatatttaa gtaacgttca gcagccatct
    21241 aaagttgaga ataaggctaa taaacccaag cctccaaaag gttggaagtg gattaaactt
    21301 attctagtag tgttgcggtt tattctaaaa cacatccttc aagaggacga tttaggaaac
    21361 taaattctcc cttggagaac acttctttag gtggttctct tttaaaaaag cttattagag
    21421 gtcttttaaa tgcttaatga tgcactactt accatgagga agtatcatcg catatctcaa
    21481 acagaattat ctcaatctct aggcatttct aactcttact tatctgaaat tgaaagtggt
    21541 aagaagaaac caactctaga gttactagat aaatattctg aatattttga tatccctgtt
    21601 tcttccttaa tgttcttttc ggaaaatatg gataaacgtg acactttatc aggaaaattt
    21661 cgttattttg ctggtagtaa agtaatcaaa cttatgaact ggttaagtga aaatggaaaa
    21721 tagtcaacct tctgattatg caaaatatgt atacgaatta gagttactga actcaccgtt
    21781 atttcatatt acaagcaaga agcgactagc tattttatta tgttcatcta ttaaagaact
    21841 gaaccatatt gttcgttcaa aaaatcagat gtatcaatat tttaatgaaa ataagactga
    21901 tgatagtgga aacattatta aagtccgccc tattcaaaat cctcatgata gattgaagca
    21961 gatccattcc agaattggga aatttttggg taacttgaaa gctcctgatt atttacattc
    22021 aaaacgttct aaatctgcaa tttcgaatgc aaaagcgcat gtcggtctta aggggcatac
    22081 gctaaatatt gatattactg atttttatcc ttctacttct aaggctaaag tgcaatcttt
    22141 ttttggatat actcttcaat acccaactga tattgctaaa tatatatctg aagtctgcac
    22201 tgtaaataat tgccttccta caggtagccc attaagttca gcattagctt tctgggctaa
    22261 taaatccatg tttgatgaaa tttatagaat ggctaaaagt cgctctataa ctatgactgt
    22321 ttatgttgac gatatttcgt ttacaggaaa ggccgtcaat caaaactttc taaataaaat
    22381 tattcaaata atagagaaat atcagcataa tattaaacaa gaaaaaatta aattttttcc
    22441 tgaaaatagc attaaattcg tcactggggt ggcaatagta aatggtagtt tacaacctgc
    22501 tcataggcat ttccgagata ttagacagct taaaaaaatt gataataata tccaagcagc
    22561 tctacgatta ataggaaaaa ataattatat aaaacaaatc attaaccatg tctaaaaatt
    22621 ctatttaaca taaaatctct tatacgaagc ccaggttaat tctgggcttt ttgttcaatc
    22681 tcatcattgg ccgagaacat acttggattc gtaagcctga tattttcctg acaacttcca
    22741 cacagcatca atcctgcaaa aagttgtaca ttttgtctat tttcacaaag cgtacatggc
    22801 tttgaaagct gaataatatt atctgacact actttaccct cttatagtta tcatctgcat
    22861 atgaataacc tttagcttgt atcattctaa cctcatcttt agaagcgcca tttttcatta
    22921 agagccacaa catcatgaaa tatagtccag aaaagtcttc atagtatttt tcagaaaaat
    22981 tgttatcttc ctcaaaatca tctattcgct tttctaatcg attcaccaga tcctcaatac
    23041 gatcggcttg ctgtttaaca gcaatagatt gaaaatcatt ggtcaaaatt ttactgaata
    23101 atttactggt tctgattcct tctgaattag ccaattgatc gtagaattct gctacttgtg
    23161 gatctaacct gactgcataa gttttgactt tttcgcccat aaattacacc tcttattaaa
    23221 attagatttt gtacaaaatt aaatatatat aattcaacta attaaataaa aaataataat
    23281 tagattacgt acaaacttat ttgtacagaa ttaatttatt ctaaaacaaa aacttattta
    23341 aatataatgc tttttttatg tacaatcatg agtacatatt ttttcttaaa tttatcaata
    23401 tcttatctaa aaaaagtgtt gttttgatgt acaaccatga gcacagcata aaaaatagat
    23461 aattcaatca cttattctaa aaaaagacca tttttctgta cacgtttctg agaccctaaa
    23521 aaatcgctga aatccttatc ctgtaaggct ttgaggggtg tcatcgttag atgcgtggtg
    23581 tgtgacaaaa aaatcccggc atgtgccgga tcttggattg gaaaattggc taaagtgacg
    23641 tagggccggt gcttggtttt gcatggaaaa aagtatttat ttccttgttt agaaaaacgt
    23701 aaaaaatcaa ttttttgtcc attcatccag gttaaaaatt tcaacccaaa actttaatta
    23761 tgaaaagctt catagaacgc gttcaaatgc gatttaagag cctttaccta gaaaacatag
    23821 atctcatagt gaaaaacaca aaacagctca aaaaacgcaa atgagagcga aataaagagg
    23881 tattttgact ttagatagat gcatagagcg agtgtctacg agcgaactat caaaatttgc
    23941 gcctagaccc tctgaaaaac atttttttgt cctctttagc ctaagaaagc gtaagtttcg
    24001 tgcagaaatt tgctcctgga tcgagcgtag cgagtaaaaa agttttatga gcgaagcgaa
    24061 ttccaagttt cttttgcttt tttttaaagt cacgccagta ttaaccaaaa aattgcccca
    24121 acgaactgag cgaaagcgaa gttcaataga gtttgagcga agcgaaaacc aagggcaatt
    24181 tttcattccc tgggctttta attattttaa agtttttaaa tacttttaaa tggcttgaaa
    24241 gccttatgaa taaagggttt tagctctt
//
