LOCUS       NZ_CP030324            27168 bp    DNA     circular CON 08-MAY-2024
DEFINITION  Staphylococcus aureus strain AR_475 plasmid unnamed1, complete
            sequence.
ACCESSION   NZ_CP030324
VERSION     NZ_CP030324.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN07291568
            Assembly: GCF_003288395.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 27168)
  AUTHORS   Benahmed,F.H., Lutgring,J.D., Yoo,B., Machado,M., Brown,A.,
            Mcallister,G., Perry,A., Halpin,A.L., Vavikolanu,K., Ott,S.,
            Zhao,X., Tallon,L.J., Sadzewicz,L., Aluvathingal,J., Nadendla,S.,
            Voskania-Kordi,A., Simonyan,V., Patel,J. and Shawar,R.M.
  TITLE     FDA/CDC Antimicrobial Resistant Isolate Bank Genome Sequencing
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 27168)
  AUTHORS   Benahmed,F.H., Lutgring,J.D., Yoo,B., Machado,M., Brown,A.,
            Mcallister,G., Perry,A., Halpin,A.L., Vavikolanu,K., Ott,S.,
            Zhao,X., Tallon,L.J., Sadzewicz,L., Aluvathingal,J., Nadendla,S.,
            Voskania-Kordi,A., Simonyan,V., Patel,J. and Shawar,R.M.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUN-2018) Center for Devices and Radiological Health,
            US Food and Drug Administration, 10903 New Hampshire Avenue, Silver
            Spring, MD 20993-0002, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: canu v. 1.4
            Genome Coverage                   :: 35.48x
            Sequencing Technology             :: Pacbio; Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003288395.1-RS_2024_05_08
            Annotation Date                   :: 05/08/2024 03:47:17
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,781
            CDSs (total)                      :: 2,699
            Genes (coding)                    :: 2,615
            CDSs (with protein)               :: 2,615
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 41 of 84
            Pseudo Genes (incomplete)         :: 41 of 84
            Pseudo Genes (internal stop)      :: 16 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP030324.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..27168
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="AR_475"
                     /db_xref="taxon:1280"
                     /plasmid="unnamed1"
     gene            complement(164..1063)
                     /locus_tag="CSC60_RS14235"
                     /old_locus_tag="CSC60_2632"
     CDS             complement(164..1063)
                     /locus_tag="CSC60_RS14235"
                     /old_locus_tag="CSC60_2632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mph(C) family macrolide 2'-phosphotransferase"
                     /protein_id="WP_000196697.1"
                     /translation="MTRHNEIIKCAEKYQLHIQPQTISLNESGLDFQVAFGKDKHGVEW
                     VLRLPRRPDVYKRTKPEKQTVDFLQKNVSFEIPKWKVHAKDLIAYPKLTGKPAATIDPE
                     IQNYVWEIEHKPLPENFINTLAETLVDLHNIPEENINVQHINIKTIQEIKNDFQRRMNK
                     VKETYGVSDELWNRWKQWLENDELWPRHATMIHGDLHPGHIMVDNQANVTGLIDWTEAT
                     HSDPSMDFIGHHRVFDDEGLEQLITAYGKAGGEIWPRMKEHIIELNAVFPMFIAEFAME
                     SGESAYETMALKELGMKE"
                     /name="Mph(C) family macrolide 2'-phosphotransferase"
     gene            complement(1162..2628)
                     /gene="msr(A)"
                     /locus_tag="CSC60_RS14240"
                     /old_locus_tag="CSC60_2633"
     ARG             complement(1166..2628)
                     /name="msr(A)"
                     /gene="msr(A)"
                     /gene_name="ABC-F type ribosomal protection protein Msr(A)"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE/STREPTOGRAMIN"
                     /identity="99.8"
                     /coverage="100.0"
     gene            3102..3776
                     /locus_tag="CSC60_RS14245"
                     /old_locus_tag="CSC60_2634"
     CDS             3102..3776
                     /locus_tag="CSC60_RS14245"
                     /old_locus_tag="CSC60_2634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="WP_001105960.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            3916..4590
                     /locus_tag="CSC60_RS14250"
                     /old_locus_tag="CSC60_2635"
     CDS             3916..4590
                     /locus_tag="CSC60_RS14250"
                     /old_locus_tag="CSC60_2635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866106.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]; GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="WP_000866106.1"
                     /translation="MKVLIVEDDLVIGKMLAEELKKWQLEPILIEGFNHVMDAFNTNAP
                     ELVLLDINLPAFNGYHWCQEIRKVSTVPIIFISSRNDSMDQVMAMQMGADDFIEKPFNM
                     TVTITKIQALLRRTYDFTTQVNNLTVDDCELLLDAAKLKFNEETIDLTHTELQIMHSLF
                     QNKGKFVSRNALIEKCWESEHFIDDNTLAVNITRLRKKLQKLGLTDFIETKKNVGYRVG
                     DV"
                     /name="response regulator transcription factor"
     gene            4587..5468
                     /locus_tag="CSC60_RS14255"
                     /old_locus_tag="CSC60_2637"
                     /pseudo=""
     CDS             4587..5468
                     /locus_tag="CSC60_RS14255"
                     /old_locus_tag="CSC60_2637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015581923.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0000155 - phosphorelay sensor kinase activity [Evidence
                     IEA]; GO:0004673 - protein histidine kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /name="sensor histidine kinase"
     gene            5584..6513
                     /locus_tag="CSC60_RS14260"
                     /old_locus_tag="CSC60_2638"
     CDS             5584..6513
                     /locus_tag="CSC60_RS14260"
                     /old_locus_tag="CSC60_2638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000074567.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016887 - ATP hydrolysis activity [Evidence IEA];
                     GO:0042626 - ATPase-coupled transmembrane transporter
                     activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000793446.1"
                     /translation="MKNLNNIIEINNLTKQYGSQIAVNNLSITVESGQIYGFLGRNGAG
                     KTTTIRMLLGLIKPTKGNIKIFEKEFESNKTEILKNIGAMVETPGFYSNLTAKENLTIN
                     AKILGIQKENAIEEVLEIVGLASEKVKLFKNYSLGMKQRLGIARALLHNPELLILDEPT
                     NGLDPIGIKEIRKLIKDLAQSRNITILISSHILSEIEQLVDKVGIIHNGVLLEEIMYED
                     LKKKNRQFISISVSDEEKVACLLETNFGIYDYKIKENGEFKIYSHIDRQQEINRLLVLN
                     NIDVFQMRVIEDNLETYFEDLVGGGTIG"
                     /name="ABC transporter ATP-binding protein"
     gene            6506..7243
                     /locus_tag="CSC60_RS14265"
                     /old_locus_tag="CSC60_2639"
     CDS             6506..7243
                     /locus_tag="CSC60_RS14265"
                     /old_locus_tag="CSC60_2639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000369394.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="WP_000369394.1"
                     /translation="MDNLLRTEFIKLKRSYMFLISILGTCVAPFMVVVASFISMRTKVP
                     TPNIVFKQLFEEVSLYHMLIIGPPLYGVIIAYLFGREYIEDTLKNLLIIPISRESFLVS
                     KIILLFLWIQTLSVIAWLLTLMLGMLLHFQGLSQSLIIDSFFTFVIGGVLLWILSPPII
                     ILSIYFKNYVPTIVLTIIITLINLMTANSEHRGLFPWAAVGDISRGTLPNTYPFLLSLI
                     IIIVTSIFSVIILFSYFKKTDIS"
                     /name="ABC transporter permease"
     gene            7257..>7433
                     /locus_tag="CSC60_RS14270"
                     /old_locus_tag="CSC60_2640"
                     /pseudo=""
     CDS             7257..>7433
                     /locus_tag="CSC60_RS14270"
                     /old_locus_tag="CSC60_2640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499250.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016311 - dephosphorylation [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /name="undecaprenyl-diphosphate phosphatase"
     gene            7490..8164
                     /locus_tag="CSC60_RS14275"
                     /old_locus_tag="CSC60_2641"
     CDS             7490..8164
                     /locus_tag="CSC60_RS14275"
                     /old_locus_tag="CSC60_2641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="WP_001105960.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            <8305..8940
                     /locus_tag="CSC60_RS14280"
                     /old_locus_tag="CSC60_2642"
                     /pseudo=""
     CDS             <8305..8940
                     /locus_tag="CSC60_RS14280"
                     /old_locus_tag="CSC60_2642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009251744.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /name="aminoglycoside 6-adenylyltransferase"
     gene            8937..9479
                     /gene="sat4"
                     /locus_tag="CSC60_RS14285"
                     /old_locus_tag="CSC60_2643"
     ARG             8938..9476
                     /name="sat4"
                     /gene="sat4"
                     /gene_name="streptothricin N-acetyltransferase Sat4"
                     /tool="amrfinderplus"
                     /drug_class="STREPTOTHRICIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            9572..10366
                     /gene="aph(3')-IIIa"
                     /locus_tag="CSC60_RS14290"
                     /old_locus_tag="CSC60_2644"
     ARG             9573..10363
                     /name="aph(3')-IIIa"
                     /gene="aph(3')-IIIa"
                     /gene_name="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            10642..>10959
                     /locus_tag="CSC60_RS14300"
                     /pseudo=""
     CDS             10642..>10959
                     /locus_tag="CSC60_RS14300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /name="HTH domain-containing protein"
     gene            complement(11019..11693)
                     /locus_tag="CSC60_RS14305"
                     /old_locus_tag="CSC60_2646"
     CDS             complement(11019..11693)
                     /locus_tag="CSC60_RS14305"
                     /old_locus_tag="CSC60_2646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105991.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            11773..12033
                     /locus_tag="CSC60_RS14440"
     CDS             11773..12033
                     /locus_tag="CSC60_RS14440"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_032603369.1"
                     /translation="MNTAIMNSVSDEYTGRSFTIWASLSLLIQSFVSPILGKGVNELGD
                     TIGFNIILIVSLIMIIFLFFINRSKNISYDYIKVQRGEANE"
                     /name="hypothetical protein"
     gene            12026..12211
                     /locus_tag="CSC60_RS14445"
     CDS             12026..12211
                     /locus_tag="CSC60_RS14445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001037130.1"
                     /translation="MNKLEKWSLVFIIFTFLSSLALLYFKYNFSSVMPVLSLSILTILI
                     LLTSIITVVSVNDEDT"
                     /name="hypothetical protein"
     gene            complement(12434..13012)
                     /locus_tag="CSC60_RS14310"
                     /old_locus_tag="CSC60_2647"
     CDS             complement(12434..13012)
                     /locus_tag="CSC60_RS14310"
                     /old_locus_tag="CSC60_2647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690624.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690637.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLNLLKTLYDNGTPI
                     KTIAEQWQVSRTTIYRYLNKLEAKENKNK"
                     /name="recombinase family protein"
     gene            complement(13276..13656)
                     /gene="blaI"
                     /locus_tag="CSC60_RS14315"
                     /old_locus_tag="CSC60_2648"
     ARG             complement(13280..13656)
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="98.41"
                     /coverage="100.0"
     gene            complement(13646..15403)
                     /gene="blaR1"
                     /locus_tag="CSC60_RS14320"
                     /old_locus_tag="CSC60_2649"
     ARG             complement(13650..15403)
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.38"
                     /coverage="100.0"
     gene            15510..16355
                     /gene="blaZ"
                     /locus_tag="CSC60_RS14325"
                     /old_locus_tag="CSC60_2650"
     ARG             15511..16352
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(16881..17300)
                     /locus_tag="CSC60_RS14335"
     CDS             complement(16881..17300)
                     /locus_tag="CSC60_RS14335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418034.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_000418035.1"
                     /translation="MELDNCINYLLSTSQNRVFKHFKSLLSPYNITPAEYGVLNCLINS
                     NLNTPKAIGNTLNLEPSTISGILDKMSKKDLITRQTDNENRRTVLINSTNKAKDLWPTL
                     EKKAYQLNNHYFANLTNEETVVFKKILLKINKTTF"
                     /name="MarR family transcriptional regulator"
     gene            17424..18395
                     /locus_tag="CSC60_RS14340"
                     /old_locus_tag="CSC60_2653"
     CDS             17424..18395
                     /locus_tag="CSC60_RS14340"
                     /old_locus_tag="CSC60_2653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="WP_000481279.1"
                     /translation="MFNAVVVRKSASNVSYKVEKVDESHLSKGDVLVKVVYSSINYKDM
                     LALQYKGGVIRDYPMIPGIDFAGIVESSSNDKFKEGDNVLVTGYDVGVTHTGGFSEYAQ
                     VPGEWIVPIPQEMSIKESMVYGTAGFTAALSIFELEKYGMNIKSQPEILVSGATGGVGS
                     VAIQILHKIGYENITAIVRKEKQIEIAKKLGAKQVIIIEDDNKPLKKGIFDYFLDTVGS
                     NVTLYGLKRLNYQGVATVCGNVAGNSLNANILPFILRGIKLIGIDSVYVDHNIREDIWS
                     KLANEWNIGNSLLYNEIGFEEFYKTIDQLLKGQHLGRTILKV"
                     /name="oxidoreductase"
     gene            complement(18567..18659)
                     /locus_tag="CSC60_RS14345"
     CDS             complement(18567..18659)
                     /locus_tag="CSC60_RS14345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(18816..19163)
                     /locus_tag="CSC60_RS14350"
                     /old_locus_tag="CSC60_2654"
     CDS             complement(18816..19163)
                     /locus_tag="CSC60_RS14350"
                     /old_locus_tag="CSC60_2654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119690.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNHEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            complement(19182..19799)
                     /gene="cadD"
                     /locus_tag="CSC60_RS14355"
                     /old_locus_tag="CSC60_2655"
     ARG             complement(19186..19799)
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(20916..21110)
                     /locus_tag="CSC60_RS14360"
                     /old_locus_tag="CSC60_2656"
     CDS             complement(20916..21110)
                     /locus_tag="CSC60_RS14360"
                     /old_locus_tag="CSC60_2656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001004925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001004925.1"
                     /translation="MNENLEKYIKSLPLLGLLISILLIVLFFFILDVDEDLFVVFLYCL
                     LPLIVNLSIYGFYVFVKRK"
                     /name="hypothetical protein"
     gene            21220..21912
                     /locus_tag="CSC60_RS14365"
                     /old_locus_tag="CSC60_2657"
     CDS             21220..21912
                     /locus_tag="CSC60_RS14365"
                     /old_locus_tag="CSC60_2657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative immunity/bacteriocin fusion bifunctional
                     protein"
                     /protein_id="WP_000691527.1"
                     /translation="MKIIKLFSIISLFLLVFSANFSNAYANEEQKSSLLENQKEKLKSK
                     NIEVSQMTKKEISFLEQLQNKNEDMQKFEKQMKKEGFKKIKLEDKNSKLKYLATEANDK
                     NAYGYIANNAYKNEKTKEIVVSETIYDNYNKKITKFIAEKRSMTENKEGKILINKNYVE
                     YKAEKVDKNRPVTYAGFKWNGKAFACSMAGLYACAHYCGVWAIVNPIAGGVCEAVCGTA
                     FAAGCSVG"
                     /name="putative immunity/bacteriocin fusion bifunctional
                     protein"
     gene            complement(22080..22229)
                     /locus_tag="CSC60_RS14500"
                     /old_locus_tag="CSC60_2658"
     CDS             complement(22080..22229)
                     /locus_tag="CSC60_RS14500"
                     /old_locus_tag="CSC60_2658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000695366.1"
                     /translation="MKIKTFATFTHRQLDKQVNRFLKNDIHVLEIQTHSNWLYISAIVF
                     YEDK"
                     /name="hypothetical protein"
     gene            complement(22776..>23065)
                     /locus_tag="CSC60_RS14370"
                     /pseudo=""
     CDS             complement(22776..>23065)
                     /locus_tag="CSC60_RS14370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009384749.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            complement(23085..24068)
                     /locus_tag="CSC60_RS14375"
                     /old_locus_tag="CSC60_2660"
     CDS             complement(23085..24068)
                     /locus_tag="CSC60_RS14375"
                     /old_locus_tag="CSC60_2660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_001181107.1"
                     /translation="MQNQYFTVQENYKERFYQIPKVFFTSENYKNLTNDMKIAYAILRD
                     RLNLSIKNSWVDEDGNIYFVYSNEKLMEILNCKKEKLTKIKKGLENDGLLIQKRRGLNK
                     PNILYLMKPIVTERDIYKIEKEENDVEPYGEKEVRKSNVQKFENRTSRSSKIERPEVRK
                     SNTNDTDFNDIDFNDTENNDMNDLNDIKYKNEISNHSNHSNQFTHNFDDKEMLLQEFPE
                     QLTNYLLKYDYRDLEIIKAVILKAKKSFNSRHEDMHYMLEDIEDEILTSLKRLKKAIHD
                     RGVKGQKETIKSMQAYLMQTILTELEETHALYMRRKNMKQYNIFNQ"
                     /name="replication initiator protein A"
     gene            24494..25237
                     /locus_tag="CSC60_RS14380"
                     /old_locus_tag="CSC60_2661"
     CDS             24494..25237
                     /locus_tag="CSC60_RS14380"
                     /old_locus_tag="CSC60_2661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843732.1"
                     /translation="MKSVKKLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESTTEDKQKKGSDNINFESKSDAQIVEILKNQIDTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNTR
                     QNVDAQEKTYTTNPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAKKEDVPANLND
                     NDSDIEEKSEETEPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     gene            complement(25464..25649)
                     /locus_tag="CSC60_RS14385"
                     /old_locus_tag="CSC60_2662"
     CDS             complement(25464..25649)
                     /locus_tag="CSC60_RS14385"
                     /old_locus_tag="CSC60_2662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011276570.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000797248.1"
                     /translation="MKNRIREYRKQKGISQETLSKELKVSRQTINAIENNKYDPTLTLA
                     FKLARLFDTTVDELFS"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(25654..25992)
                     /locus_tag="CSC60_RS14390"
                     /old_locus_tag="CSC60_2663"
     CDS             complement(25654..25992)
                     /locus_tag="CSC60_RS14390"
                     /old_locus_tag="CSC60_2663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001049146.1"
                     /translation="MNLIPFIIILIFSCLWTAITNKYLPSETLDKKGQQDRYDERQRKM
                     FIEILAKSFIWIVYCMLFTLVLKFTGLSPSIEGSWFSQYPEIFFIIVALFLMLFNYYTT
                     NKKYTSKG"
                     /name="hypothetical protein"
     gene            complement(26238..26846)
                     /locus_tag="CSC60_RS14395"
                     /old_locus_tag="CSC60_2664"
     CDS             complement(26238..26846)
                     /locus_tag="CSC60_RS14395"
                     /old_locus_tag="CSC60_2664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002474535.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000583528.1"
                     /translation="MIIGYARVSSIDQNLERQLDNLKTFGVEKIFTEKQSGKSVENRPV
                     FQEALNFVRMGDRFVVESIDRLGRNYDEIIETVNYLKEKDVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRV
                     IYHRVVEMLEEGKAISKIAKEVNITRQTVYRIKHDKGLS"
                     /name="recombinase family protein"
     ARG             complement(168..1063)
                     /name="mph(C)"
                     /gene="mph(C)"
                     /gene_name="Mph(C) family macrolide 2'-phosphotransferase"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(1163..2628)
                     /name="msrA"
                     /gene="msrA"
                     /gene_name="msr-type ABC-F protein"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; streptogramin
                     antibiotic; streptogramin B antibiotic"
                     /identity="98.16"
                     /coverage="100.0"
     ARG             complement(165..1063)
                     /name="mphC"
                     /gene="mphC"
                     /gene_name="macrolide phosphotransferase (MPH)"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="98.66"
                     /coverage="100.0"
     ARG             8938..9479
                     /name="SAT-4"
                     /gene="SAT-4"
                     /gene_name="streptothricin acetyltransferase (SAT)"
                     /tool="rgi"
                     /drug_class="nucleoside antibiotic"
                     /identity="99.44"
                     /coverage="100.0"
     ARG             15511..16355
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     ARG             8342..8940
                     /name="aad(6)"
                     /gene="aad(6)"
                     /gene_name="ANT(6)"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="99.5"
                     /coverage="72.1"
     Typing          complement(22573..22720)
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="5.980000000000001e-72"
     Typing          complement(22779..22954)
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="92.697"
                     /coverage="94.0"
                     /evalue="1.04e-65"
     Typing          complement(23086..24068)
                     /name="rep_cluster_2100"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.492"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          24495..25237
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 agttagaaat ttcgaaaacg attctttcca tttgttgcat ttgttccatg tccagatatt
       61 taatacatta tagaaaacca aagaccatca ctaattaaac gcagttttaa aatttcatca
      121 ggattgcctt cgtctttaaa atgggcctct tttaatataa gttctactct ttcataccta
      181 actctttcaa tgccatcgtt tcatacgccg attctcctga ttccatagca aactcagcga
      241 taaacattgg gaatactgca ttgagttcta ttatatgctc tttcattcgt ggccatattt
      301 cacctccagc tttaccgtat gctgttataa gttgctctaa tccttcgtcg tcgaatacac
      361 gatggtgtcc tataaagtcc attgatgggt cggagtgggt tgcttcagtc cagtctatga
      421 gacctgtgac gtttgcttgg ttatctacca ttatatgtcc tggatgtaag tccccatgta
      481 tcatggtcgc atgtcgaggc catagttcgt cgttttctaa ccattgtttc catctgttcc
      541 ataattcatc tgatacgcca taagtttctt taactttatt cattcttctt tgaaagtcat
      601 tttttatttc ttgtatggtt ttgatattta tatgctgaac gttaatgttt tcttctggta
      661 tgttgtgtaa atctacgagt gtttcagcta atgtgttaat aaagttttct ggtaatggtt
      721 tgtgttcaat ttcccataca taattttgta tttctggatc tattgtggct gcgggtttac
      781 ctgtaagttt tgggtaagca ataaggtctt ttgcatgtac tttccacttc ggtatttcaa
      841 atgaaacatt cttctgtaag aagtctaccg tttgtttttc gggttttgtt cgtttataaa
      901 cgtcaggtct tcttggtagt ctcaaaaccc attctactcc atgtttatct tttccaaatg
      961 caacttgaaa atcaagtccc gattcattca atgagattgt ttgaggttgg atgtgtaatt
     1021 gatatttttc tgcacattta ataatttcat tatgtcgagt cattttattg gatccttatt
     1081 tctattatat ttttcttgtg aacgtatttt ttatattgat ataaatgaac ctaatattca
     1141 atataaatta gtgtatagtt tttaagttat atcatgaaga gattgtcctg ttaattccca
     1201 ttttttatct gatacatgtt taacaaacct tgtatcatgt gatgtaaaca aaatgattcc
     1261 aggatattta ttcataaaca tttctaatgc ttctaatgtt ttaatatcta aaaaattagt
     1321 tggttcatcc aaaattaaca tattcgcttt cgttgaaaat aatactgcta acgataattt
     1381 cgttctttcc ccaccactca aaacattaca agaacgatca agtgcttcat ttaaacccaa
     1441 gttatttaaa atagctctac tgaatgattc tgatgaatcc gtttcatcca ttaaatattg
     1501 caataatgaa acgtcacgca tgtcttcata agcaagttga cgatagtatg ccatttgcac
     1561 tttaggagaa caatcaattc cctctatttg gtggtaaata gcttcaagta aagttgtctt
     1621 acctacacca tttgcaccta cgagcgctat atttttgcca tatggtattt ggaatcgtac
     1681 ttgtgttagc agtttttgac ttcctttaac caatgttaga ttttgtgcaa tgattggata
     1741 attattatgg atatcataaa ttttattttg tgggaaattg aattcatgat aactttgtgg
     1801 tttttcaact tcttccaaat gttccattct tttttcaata tgcttagctt gtttttgagc
     1861 agccttctca accgtgcctt tttgttttga tgcacttaaa cgatctggtg ctatactttt
     1921 gtttttttgt tttgatgatg cttgtgccat ttgttgcgct tgatttcgtt tagctttact
     1981 ggcttgggac aatctttgtt tttcacttat atactgttca tattgacgtt gttgttctaa
     2041 ctgttcttgt tcatattgat tttgatactg tgtgtaatta cctttaaaca ctcttattgt
     2101 gccatcttct tgtatatccc aaattgtgtc agcaatttgg tctataagtg ctctatcatg
     2161 acttactata attaaagtac catagtaata ttttaaaata tttttcagat aatctttacc
     2221 aattttatcc aagtgatttg taggttcatc taaaagtaat atcggactat aatttgatat
     2281 gacattagct aatttatatt ttgctttttc accaccactc atactgtcgg ttgtatgcat
     2341 aggtatatgg agttcactca ttaaactacc gtctaacgtg ttaaaatcat tttccacatc
     2401 catgttaagc tgttcaaaat attgaatttc gccaaccgtt tcaactgttc cagattctgg
     2461 ttttgttttt tgagcaatca tatttagtaa tgtggttttg ccagtaccat tacccccaat
     2521 aagtgctatt ttttcaaatt ggtaagcgta aatatgaccg atgttaagtg atcgtaaatc
     2581 tgtcaattta tgattgattt ggttaaattt aattgtatat tgttccatat ttatacactc
     2641 cttgtatatt taaaggacgt gtacgcaaaa aaatgagaca ggctactccc gtctcattca
     2701 cattacactt tcaaacactt aaaaatttat tatgatgttt tagtatttga aagcgtttat
     2761 tattcctatc gaaggataaa aaatgacata agtcatccta tgagtgtgta ttgcggacaa
     2821 gcctttttga attaatttag ttttgtattc aaaaaggttt atttgagtct catagaagct
     2881 gtcattttaa tcctccttca tcgataaaat agtaatgtta atataacatt ttgttggttt
     2941 ttttacaata tatctctaag tagaaagatt atataacaaa agtataaaaa tacaatttta
     3001 gattgattat acatctcctt aatttagagt gtactcataa aatacggttc tgttgcaaag
     3061 ttgaatttat aatataattt taacaaaaag gagtcttctg tatgaactat ttcagatata
     3121 aacaatttaa caaggatgtt atcactgtag ccgttggcta ctatctaaga tatgcattga
     3181 gctatcgtga tatatctgaa atattaagag aacgtggtgt aaacgttcat cattcaacga
     3241 tctaccgttg ggttcaagaa tatgccccaa ttttatatca aatttggaag aaaaagcata
     3301 aaaaagctta ttacaaatgg cgtattgatg agacgtatat caaaataaaa ggaaaatgga
     3361 gctatttata tcgtgccatt gatacagagg gacatacatt agatatttgg ttgcgtaagc
     3421 aacgagataa tcattcagca tatgcgttta tcaaacgtct cattaaacaa tttggtaagc
     3481 ctcaaaaggt agttacagat caggcacctt caacgaaggc agcaatggct aaaataatta
     3541 aagcttttaa acttaaacct gactgtcatt gtacatcgaa atatctgaat aacctcattg
     3601 agcaagatca ccgtcatatt aaagtaagaa agacaagata tcaaagtatc aatacggcaa
     3661 agaatacttt aaaaggtatt gaatgtattt acgctctata taaaaagaac cgtaggtctc
     3721 ttcagatcta cggattttcc ccatgccacg aaattagcat catgctagca agttaaacga
     3781 acactgacat gatatattag tgattagcta tattttttac tttgcaacag aaccaacaaa
     3841 aaccgtgcca gaattatttc ttatcttccc ctcatttatg tcataataat aaaaaacgac
     3901 tgtggtggtg agatgatgaa agtattaatc gtagaggatg acttagttat cgggaagatg
     3961 cttgctgaag agctcaagaa gtggcagcta gaaccgatct taatagaagg tttcaatcat
     4021 gtaatggatg ccttcaacac gaatgcaccg gaacttgtgt tactcgatat taatttacct
     4081 gccttcaatg gttatcactg gtgtcaggag attcgtaaag tttctactgt accgattata
     4141 tttattagtt cgcgtaacga cagtatggat caagtaatgg cgatgcagat gggtgcggat
     4201 gatttcattg agaagccatt taatatgact gttacaatta ctaagattca agcactatta
     4261 cgccgcacgt atgatttcac cactcaagtt aataatttaa cagtagatga ttgcgagtta
     4321 ctacttgatg cagcaaagct taaatttaat gaagaaacca tagacctgac acacactgaa
     4381 ttgcaaatca tgcatagctt attccagaac aagggcaaat tcgtcagtcg taatgcgtta
     4441 atcgaaaaat gctgggaatc agaacacttc attgatgaca atacgcttgc tgtcaacatt
     4501 acacgtttac gcaaaaagct acaaaaacta ggacttacag attttatcga aacgaagaaa
     4561 aatgtcggat atcgtgtagg tgacgtatga atttcttgaa atcaatccaa cgtgaaattt
     4621 atattgtcat ccttacttgt gctttattct actttatatt attcatgtat aatgtgccga
     4681 tgcaagcata tatgattggt ctaggtattg tattgtttgt ttcaatgatt tactggggta
     4741 tccattacat gaactttaaa aaagaataaa cactacagga acagaacgaa gatttaagaa
     4801 tcgaaaacca taaacttcgt aatgacttta ttaactacca aagtgagtta gagtcatatt
     4861 ttttaatgtg ggtgcatcaa atcaagacac cgattacagc atcaaagtta ctgcttgaag
     4921 atcctgatga acacgtgatt tctaacgtgc gtaatgaagt cttacaaatt gataattaca
     4981 cgaatcttgc actgaactat ttgaaactca tgaaccaaaa gacatacatg gtctttatgg
     5041 aagtgagtgt agatgaatta attcgaccac tgattaaacg ttatgcgata cagtttattc
     5101 atcatcaaac aaagttgcat tatgagaaaa gtgaagcggt tatattaaca gatgccaaat
     5161 gggcatcaat tatgattgag caaatattaa acaatgcatt aaaatatgca cgtggcaaag
     5221 atgtgtggat tacgtttgac gaaaatacaa agaaattatc aatccgagat aacggtatcg
     5281 gcattaatgc gagtgattta ccgaaaatct ttgataaagg tttctcgggc tataacggta
     5341 gaataagtga gaaatcaagc ggtattggtt tatatattgt cagcacaatc tcaaagcgct
     5401 taggccataa agtaagtgct acatctacat taaacgatgg ttcaatattc accattcaat
     5461 ttaaataact ccaatctttc atttttgtaa gattagcggc tgtttttgta agaatagata
     5521 aaggcagcct tttctaatcg cgcgtaagat aaaggtaaca acaaactaag aaaggtgcca
     5581 gaggtgaaaa atttgaataa tataattgaa ataaataact taacaaagca atatggaagt
     5641 cagatagcag ttaataattt gagtataact gttgaaagtg gacaaattta tggtttttta
     5701 ggaagaaatg gtgcaggcaa aacaactact ataagaatgc ttttaggctt aattaaacct
     5761 acgaaaggta atattaaaat atttgaaaaa gagttcgaaa gtaataaaac tgaaatttta
     5821 aaaaatattg gtgctatggt tgaaacgcca ggtttttata gtaatttgac agctaaagag
     5881 aacttaacta taaatgctaa aatattaggt atacaaaaag aaaatgcaat tgaagaagtg
     5941 ttagaaatag taggactagc ttctgaaaaa gtaaaattgt ttaaaaatta ttctttaggt
     6001 atgaagcaac gtttagggat tgcgagagct ttattgcaca atcccgaatt attgatactt
     6061 gatgagccga cgaatggatt agatcctatt ggcataaaag aaattagaaa gttgattaag
     6121 gatctggctc aatctagaaa tataaccatt ttaatttcaa gtcatatatt gtcagaaata
     6181 gagcagttag tagacaaggt gggtattatt cataacggag ttttgttaga agaaattatg
     6241 tatgaagatt taaaaaaaaa gaacagacaa tttataagta tatcagtatc agatgaagaa
     6301 aaagttgcat gtttgttgga aactaacttc ggaatttatg actataaaat taaagaaaat
     6361 ggcgaattta aaatttattc acatattgat agacaacaag aaattaatag attattagta
     6421 ttaaacaata ttgatgtttt ccagatgaga gtgatagaag ataatctaga aacttatttc
     6481 gaagacttag taggaggtgg cacaattgga taatctactc cgtacagaat ttattaagtt
     6541 aaaaagatca tatatgtttc taataagtat tttaggtaca tgcgtagcac cttttatggt
     6601 ggttgtagct tcttttatta gtatgcggac gaaagtaccg actcctaata ttgtatttaa
     6661 acagttattt gaagaagtca gtttatatca tatgctaatt attggacctc ctctatatgg
     6721 ggttataata gcctatttgt ttggaagaga atatatagaa gatactttaa aaaacttatt
     6781 aattatacct atatctagag aaagtttttt agtaagtaaa ataatattat tattcttgtg
     6841 gattcaaaca ctatctgtta ttgcatggtt gctaacttta atgctaggta tgctattgca
     6901 ttttcaaggg ttaagccaga gtttaataat tgattcattc tttacatttg ttattggcgg
     6961 agtgttatta tggatattat ctccaccaat aattattttg tcgatatatt ttaaaaatta
     7021 tgttcccaca attgttttaa ccataataat tactttgata aatttaatga ctgctaattc
     7081 tgaacataga ggattatttc cttgggctgc agttggagac atatctagag gaacattacc
     7141 taatacttat ccatttctat tatctttaat tatcataatt gttacatcta tattcagtgt
     7201 aattatatta ttctcatact ttaaaaaaac tgatataagt taaaaggagg agaaaaatgg
     7261 gttttataga gcagattaaa gcatttattt taggtgtagt tgaagggttg acagaatttg
     7321 ctccagtatc atcaacaggt catatgatta ttgttgatga tatgtggtta aacactgctg
     7381 acgatttagg aagtgcgtct gcaactactt ttaaggtggt aatacagtta ggaggttctg
     7441 ttgcaaagtt gaatttataa tataatttta acaaaaagga gtcttctgta tgaactattt
     7501 cagatataaa caatttaaca aggatgttat cactgtagcc gttggctact atctaagata
     7561 tgcattgagc tatcgtgata tatctgaaat attaagagaa cgtggtgtaa acgttcatca
     7621 ttcaacgatc taccgttggg ttcaagaata tgccccaatt ttatatcaaa tttggaagaa
     7681 aaagcataaa aaagcttatt acaaatggcg tattgatgag acgtatatca aaataaaagg
     7741 aaaatggagc tatttatatc gtgccattga tacagaggga catacattag atatttggtt
     7801 gcgtaagcaa cgagataatc attcagcata tgcgtttatc aaacgtctca ttaaacaatt
     7861 tggtaagcct caaaaggtag ttacagatca ggcaccttca acgaaggcag caatggctaa
     7921 aataattaaa gcttttaaac ttaaacctga ctgtcattgt acatcgaaat atctgaataa
     7981 cctcattgag caagatcacc gtcatattaa agtaagaaag acaagatatc aaagtatcaa
     8041 tacggcaaag aatactttaa aaggtattga atgtatttac gctctatata aaaagaaccg
     8101 taggtctctt cagatctacg gattttcccc atgccacgaa attagcatca tgctagcaag
     8161 ttaaacgaac actgacatga tatattagtg attagctata ttttttactt tgcaacagaa
     8221 ccatcatttt tattaaaata ctcttttgta aaatctttct gctcttcaat gtatttaatt
     8281 tctttacctc taaatctatt atagctattt gatgattaca ataaaattga tcttacctta
     8341 ttgcccttgg aagagttaga taattaccta aagggcgata aattaataaa ggttctaatt
     8401 gataaagatt gtagaattaa aagggacata gttccgactg atatagatta tcatgtaaga
     8461 aagccaagcg caagggagta tgatgattgc tgcaatgaat tttggaatgt aacaccttat
     8521 gttattaaag gattgtgccg taaggaaatt ttatttgcta ttgatcattt taatcagatt
     8581 gttcgccatg agctgctgag aatgatatca tggaaggtcg gcatcgaaac aggctttaaa
     8641 ttaagtgtag gcaagaacta taagtttatt gaaaggtata tatccgagga tttgtgggag
     8701 aaacttttgt ccacctaccg gatggattcc tatgaaaaca tatgggaagc attatttcta
     8761 tgccatcaat tgttcagggc ggtatccggt gaggtggcgg aaaggcttca ttatgcctat
     8821 ccggagtatg ataggaatat aacaaaatat accagggaca tgtataaaaa atacactggt
     8881 aaaaccggct gcctggatag cacatatgcc gctgatatag aagagaggcg ggaacagtga
     8941 ttacagaaat gaaagcaggg cacctgaaag atatcgataa acccagcgaa ccatttgagg
     9001 tgataggtaa gattataccg aggtatgaaa acgagaattg gacctttaca gaattactct
     9061 atgaagcgcc atatttaaaa agctaccaag acgaagagga tgaagaggat gaggaggcag
     9121 attgccttga atatattgac aatactgata agataatata tctttactac caagacgata
     9181 aatgcgtcgg aaaagttaaa ctgcgaaaaa attggaaccg gtacgcttat atagaagata
     9241 tcgccgtatg taaggatttc agggggcaag gcataggcag cgcgcttatc aatatatcta
     9301 tagaatgggc aaagcataaa aacttgcatg gactaatgct tgaaacccag gacaataacc
     9361 ttatagcttg taaattctat cataattgtg gtttcaaaat cggctccgtc gatactatgt
     9421 tatacgccaa ctttgaaaac aactttgaaa aagctgtttt ctggtattta aggttttaga
     9481 atgcaaggaa cagtgaattg gagttcgtct tgttataatt agcttcttgg ggtatcttta
     9541 aatactgtag aaaagaggaa ggaaataata aatggctaaa atgagaatat caccggaatt
     9601 gaaaaaactg atcgaaaaat accgctgcgt aaaagatacg gaaggaatgt ctcctgctaa
     9661 ggtatataag ctggtgggag aaaatgaaaa cctatattta aaaatgacgg acagccggta
     9721 taaagggacc acctatgatg tggaacggga aaaggacatg atgctatggc tggaaggaaa
     9781 gctgcctgtt ccaaaggtcc tgcactttga acggcatgat ggctggagca atctgctcat
     9841 gagtgaggcc gatggcgtcc tttgctcgga agagtatgaa gatgaacaaa gccctgaaaa
     9901 gattatcgag ctgtatgcgg agtgcatcag gctctttcac tccatcgaca tatcggattg
     9961 tccctatacg aatagcttag acagccgctt agccgaattg gattacttac tgaataacga
    10021 tctggccgat gtggattgcg aaaactggga agaagacact ccatttaaag atccgcgcga
    10081 gctgtatgat tttttaaaga cggaaaagcc cgaagaggaa cttgtctttt cccacggcga
    10141 cctgggagac agcaacatct ttgtgaaaga tggcaaagta agtggcttta ttgatcttgg
    10201 gagaagcggc agggcggaca agtggtatga cattgccttc tgcgtccggt cgatcaggga
    10261 ggatatcggg gaagaacagt atgtcgagct attttttgac ttactgggga tcaagcctga
    10321 ttgggagaaa ataaaatatt atattttact ggatgaattg ttttagtacc tagatttaga
    10381 tgtctaaaaa gctttaacta caagcttttt agacatctaa tcttttctga agtacatccg
    10441 caactgtcca tactctgatg ttttatatct tttctaaaag ttcgctagat agagttctat
    10501 attagagatg taaagagttt tggtgaagag gtttgtgagt atggctttta taaccagggt
    10561 gcaatgagaa gcactaacag cagctagctt aagaacgcat aggatatact ttttatggaa
    10621 gtcacagagg aggaataaaa tttgaacagg attaacagag taacctctat tcttattcag
    10681 ctgcaatcaa aaaaaataat tcctgccaaa gaaattgcac agcgatttaa tataagctta
    10741 aggacagttt acagagatat ccggacactt gaagaagccg gaataccaat tggatctgag
    10801 gccggaaaag gatattttct tgtagagggc ttcctacttc cgccggtaat gtttacagcg
    10861 gcggaagtgg gtgcattgat tacagcaggg aaatttttaa attgccatgg agatgaatca
    10921 tttataaagg attttgattc agctatgtat aaaatcaaag gttctgttgc aaagtaaaaa
    10981 aatatagcta accactaatt tatcatgtca gtgttcgctt aacttgctag catgatgcta
    11041 atttcgtggc atggcgaaaa tccgtagatc tgaagagacc tgcggttctt tttatataga
    11101 gcgtaaatac actcaatacc ttttaaagta ttctttgctg tattgatact ttgatacctt
    11161 gtctttctta ctttaatatg acggtgatct tgctcaatga ggttattcag atatttcgat
    11221 gtacaatggc agtcaggttt aagtttaaaa gctttaatta ctttaaccat tgctaccttc
    11281 gttgaaggtg cctgatctgt aattaccttt tgaggtttac caaattgttt aatgagacgt
    11341 ttgataaacg catatgctga atgattatct cgttgcttac gcaaccaaat atctaatgta
    11401 tgtccctctg catcaatggc acgatataaa tagctccatt ttccttttat tttgatgtac
    11461 gtctcatcaa tacgccattt gtaataagct tttttatgct ttttcttcca aatttgatat
    11521 aaaattgggg catattcttg aacccaacgg tagaccgttg aatgatgaac gtttacacca
    11581 cgttccctta atatttcaga tatatcacga taactcaatg catatcttag atagtagcca
    11641 acagctacag tgataacatc cttgttaaat tgtttatatc tgaaatagtt catacagaag
    11701 actccttttt gttaaaatta tactataaat tcaactttgc aacagaaccg catttcttct
    11761 attagaattt atatgaatac cgcgattatg aacagtgtgt ctgatgaata cactggaagg
    11821 tcatttacta tatgggcatc tctttcatta ttaatacaaa gctttgtatc tccgatatta
    11881 ggcaaaggtg taaacgaatt aggtgatact ataggattca acattatatt aatcgtttct
    11941 ttaataatga ttatcttctt attttttata aatcgtagta aaaatatctc ctatgattat
    12001 ataaaagttc aaagaggtga agccaatgaa taaattagaa aaatggtctt tggtatttat
    12061 tatttttaca tttctctctt cattagcact tttatatttc aaatataatt ttagttcggt
    12121 tatgccagtc ctaagtcttt ctattttaac tatactaata ttgttgacga gtattattac
    12181 tgtagtttca gttaatgatg aagatactta aaacgttcat tagtgaaaca ggtattatat
    12241 taaaaaagcg tacgaatttg tacgcttttt tcttgtgtta ttattaaaat ctcataacag
    12301 gaaaatatta tgagatttta gacgctgtca gaacgtctct tttacatcga gtgacattga
    12361 atcaaagtct ttgtatgtta atgatatata aaattattta gtagattcat tatagtaagc
    12421 tagattagtt gctctacttg tttttattct cttttgcctc taatttattg agataacgat
    12481 aaatagttgt acgtgaaact tgccactgct ctgcaattgt tttaattggc gtaccattat
    12541 cataaagtgt cttaagtaag tttaaatctt gtttatttaa tttttcaggt ctacctccat
    12601 atcggcctct agcacgtgct gcaattcgac cggctgatga tcgctctaaa attaaattac
    12661 gttcaaactc tgcaaatgct gcgaataaat gaaataataa ttgtcctgta gaacttgatt
    12721 tatccatcgt tatattttct tctaaactat gaaaactcac acctcgttcg ttaagttcat
    12781 taactaacgt gattaaatcc tccatgttcc gtcctagtct atctaatctc caaacaacaa
    12841 tcgtatctcc tgacctcgca aattcaattg ctttatctaa accaggtcgc ttactttttg
    12901 aaccactcat atggtcatta aatatctttt cacaaccata tgtatttaat cgatcctcct
    12961 gtaaattcaa attttgtaat ccagttgaaa ctcttgcata acctattttc aaaatacaga
    13021 cctcctatat acacctttag tgtaccataa cttgattacg aggtcttttg tgaacataga
    13081 ttttttgttg ggtttttgaa cacataattc tatgtaatac ttacttattt agacaaaaaa
    13141 caagagtgta cagaaaatgg ttattttctg gacactctca tctttaataa tatattttaa
    13201 atgtcattaa caaaactaat ttaataagag tcaagtatgg tttacatatg tattatgttt
    13261 gaaacatacc tctaattact ttttactaat atcatttaaa atgtctcgca attcttcaat
    13321 ttctttgtta tttaattctt catttttcgc aaaattcagc actaaacttt tcatatcccc
    13381 tccatacagt ttattaagaa aggttttagc agttttcatt ttaatatcgt cttctttaat
    13441 atttgatgag taaaaataaa tattttctga tttgtatcgt tttataatct cttttttata
    13501 tagtcttgtg attaatgttc taatcgtttt atcactaact tctttatatt tttgaatttc
    13561 aactacaatt tcattagctg atactgattt tttatcccat attatattca taacatccca
    13621 ttcagccata gatatttcaa cttgcttatt ggtcatttaa aacacccatt ccttttaata
    13681 ttttttcact tattaattca gcatttttcc cagacgggtt tccatctgat aaatgtgtag
    13741 caaaataata cttatcatga tttgtaatta cgtaacctac aaaccaccca ttattatact
    13801 tcccgtttac tatacctgta cctgttttcc catacagttc atacttttca tttttcttaa
    13861 tcaataatga agaagataat tgattctttg cttttttact aaaatggtta ttttgttcca
    13921 tcatattttt aaaaactatt acttgttcaa gattagatat tttcaaacta tcttccatcc
    13981 aatagctttt ataacttccc aaattttcat taccataatt taattgcttg agttgagccg
    14041 cagtatagtt ctttggtatt tgattactaa tacgttcgaa gtaccaatta actgaatttt
    14101 gcattgctgt atttaaatct tgttccttat tccaagactc gaaaagataa tgtttatgat
    14161 tccatgacat acgtgaattt ttatcactta taatatgacg gtcaagtcca aacagtgcta
    14221 aataaatttt gtaagttgaa tcaggagaat atctttttct actttctttt tcattataaa
    14281 tatagtattt gtctttcttc atgctgtaca taacgaaaga tccactattt gaaccaaaat
    14341 ttttactttc atctaaaatt tggtaatcgc tttgtaaggg ctttttataa ttataatcag
    14401 ttaaggattg ccccattaaa aactggcttt gaattatcat gataaaaaaa gtaaaaatac
    14461 aaataaaaat tagaattaat tttgactgct ttttcagatc ggcttctttt atattaatta
    14521 atctactttt gagtaatgat tttttaccat taaatgaatg gcttaatata tttttgttgg
    14581 aaaatggggt ttttaatacg gagtccataa tagattccgc ataagtttta aattcatttt
    14641 tgttaatatt attaaggaca aatctatcgg cttctacttc attgtcatga attatctttc
    14701 tttttacaat atgtactaat ggattgtaac tcataataat agagaagata ttaaagataa
    14761 ttaaatgtaa agtatctcta tttttagcat gagcatattc atgcagtatt atatatttta
    14821 gtcttttatc aattacactt ttaaaatatg aactaggaat caaaataata tatttcccat
    14881 accaaaaagt tattggagat tgaatagcct ctgcttttcg aatcacaata ttttttttat
    14941 attgatggtt gaaaagtatc gtatctattt tatttttttc attttcgttt agataaagtg
    15001 actgtttctt taaatattta agatataata aggctttcaa aaatttaaaa cttaaaataa
    15061 taactaaaac tatccaaata actgtgcaga tattatcaat tgaatcccaa ttaaacttat
    15121 ggatatctgt tgtgaactct tgaataggtt tggtggtatt tatgttatgg ttcaaatcgt
    15181 gtgacttact ttcaactgtg ggcgcttgat tattcacatt attaaatttt ataaaagaga
    15241 atttaattgg gataaaagga attaatccag caagcatagt tagataccaa actttataat
    15301 ttaaactata attaaaatag cgttttaata tgtacctaaa aaatactaac aatagaaata
    15361 taaaacaaaa gcttactacg ctcattatta gtaatttagc cattttgaca ccttctttca
    15421 aatatttata ataaacaatt gacatcaata ttacaattgt aatattattg atttataaaa
    15481 attacaactg taatatcgga gggtttattt tgaaaaagtt aatattttta attgtaattg
    15541 ctttagtttt aagtgcatgt aattcaaaca gttcacatgc caaagagtta aatgatttag
    15601 aaaaaaaata taatgctcat attggtgttt atgctttaaa tactaaaagt ggtaaggaag
    15661 taaaatttaa ttcagataag agatttgcct atgcttcgac ttcaaaagcg ataaatagtg
    15721 ctattttgtt agaacaagta ccttataata agttaaataa aaaagtacat attaacaaag
    15781 atgatatagt tgcttattct cctattttag aaaaatatgt aggaaaagat atcactttaa
    15841 aagaacttat tgaggcttca atgacatata gtgataatac agcaaacaat aaaattataa
    15901 aagaaatcgg tggaatcaaa aaagttaaac aacgtctaaa agaactagga gataaagtaa
    15961 caaatccagt tagatatgag atagaattaa attactattc accaaagagc aaaaaagata
    16021 cttcaacgcc tgctgctttc ggcaagactt taaataaact tatcgcaaat ggaaaattaa
    16081 gcaaaaaaaa taaaaatttc ttacttgatt taatgtttaa taataaaaac ggagacactt
    16141 taattaaaga tggtgttcca aaagactata aggttgctga taaaagtggt caagcaataa
    16201 catatgcttc tagaaatgat gttgcttttg tttatcctaa gggccaatct gaacctattg
    16261 ttttagtcat ttttacgaat aaagacaata aaagtgataa gccaaatgat aagttgataa
    16321 gtgaaaccgc caagagtgta atgaaggaat tttaatattc taaatgcata ataaatactg
    16381 ataacatctt atagtttgta ttatattttg tattatcgtt gacatgtata attttgatat
    16441 caaaaactga ttttcccttt attattttcg agatttattt tcttaattct ctttaacaaa
    16501 ctagaaatat tgtatataca aaaaatcata aataatagat gaatagttta attataggtg
    16561 ttcatcaatc gaaaaagcaa cgtatcttat ttaaagtgcg ttgctttttt ctcatttata
    16621 aggttaaata attctcatat atcaagcaaa gtgacaatag cattttacaa gtatttttta
    16681 ttgttcgatt agggtaaacc taaataatac ataaattata ttacaatatg tttattatag
    16741 aggctaaagt atcttagaaa tttggatagt aggtttttcg ggaataaaag tatagttggc
    16801 tttaatatat aattaagcta agctatcatt tatatttact cgattataat tcgcacttca
    16861 actttttaat aacgtaaaaa ttaaaacgta gttttattta tctttagtaa tatcttttta
    16921 aacactacag tttcttcatt agttaaatta gcgaagtaat gattattaag ttgataggct
    16981 ttcttttcta atgttggcca taagtctttt gctttatttg tactgtttat tagcacagtt
    17041 cttctatttt cattatcagt ttgacgtgtt attagatcct ttttggacat cttatctaat
    17101 attccagata ttgttgaagg ttctaaattt aaagtattac caatcgcttt aggtgtattc
    17161 aaattactat taatcaagca attcaaaaca ccatattctg ctggagtaat attataggga
    17221 cttaataaac ttttaaaatg tttaaaaact ctattctgag aagtactcaa caaataattt
    17281 atacaattat ctaattccac aactaaaacc tctcttaaat cattagtatt gactcgctta
    17341 tcatatcatg ataagttttg taggaaaata gttttgcaac aaaaacatac ttctacaaaa
    17401 caattgtgaa agaaggctaa taaatgttca atgcggtagt agtgagaaaa agtgcatcaa
    17461 atgttagtta taaagtagaa aaagttgatg aatctcattt atcgaagggt gatgtattag
    17521 taaaagtggt atactcttca ataaattata aggatatgct agctttacaa tataaaggcg
    17581 gtgtaattag agattatcct atgattcctg gtatagattt tgcaggtatt gttgaatcaa
    17641 gttcgaatga taagtttaaa gaaggcgata atgtattagt tactggttat gatgttggcg
    17701 tgacacatac aggtggattt tcagaatatg cacaagtgcc tggagagtgg attgttccta
    17761 ttccccaaga aatgtctatt aaagagtcta tggtatatgg cacagccggt tttacggcag
    17821 cattatcaat ttttgaacta gaaaaatatg gaatgaatat caaatcacaa cctgaaattt
    17881 tagtgtctgg ggctacaggt ggtgtgggca gtgttgctat acaaatttta cataaaattg
    17941 gatatgaaaa tatcactgct atcgtaagaa aagaaaagca aatagaaatc gcaaaaaaat
    18001 taggtgcaaa acaagtaata ataattgaag atgataataa accgcttaaa aaaggtattt
    18061 ttgattattt cttagataca gtggggagta atgtaacatt atacggttta aaacgtctaa
    18121 attatcaagg tgttgctact gtatgtggaa atgtagcagg aaattcactt aacgctaata
    18181 tattaccgtt tattcttaga ggtattaaat taattggcat tgattctgta tatgttgatc
    18241 ataatatccg tgaagatata tggagtaagt tagcaaatga atggaatata ggaaattcac
    18301 ttctatacaa tgaaattgga tttgaagaat tctataaaac gatagatcag cttttaaaag
    18361 gacaacattt aggaagaact attttaaaag tataagtgtg agtattcatt aatacattta
    18421 ctattaattc aatcattttg catttctcta ctaaccagtg ttataattta tataacgaaa
    18481 atgattaaca attaatgcac caatccccac actattgcag tagtgtgggg attttttcga
    18541 tgctggctta taaagtcgcc tattaattat ttgttgcgtt tactaagcca ataagtataa
    18601 tacgcaacag cacagccact gatgactggt gctatgatgt gaacgaaaat gattagcaaa
    18661 gtaatgcacc tcctctcttc gtcaattgac gcctgagaga taggcgactc tattattata
    18721 ccatctgtga atatacaagc atatctactt ccgataagtc gtcttatgtt atataacttt
    18781 gttttttata gtatcaagac aagaagaaac tcgtttcaaa aaccctcatg atttttagag
    18841 aaaaactctc ttatttcatc gtctttaata aaataatatg ccatctttcc atctttataa
    18901 aaatcaagta cctcattttt atataaaagc cttaaatgat gtgaagttga agcaacactc
    18961 attttcaata tcaaagaaat atcacaaaca cacaactcat cttctttaat caaagataat
    19021 atgattttca atttcttctc atcacaaatt ttttctaaaa tgttaagtaa tttcttagat
    19081 ttatcatctt ctaaaaaact taaagcattg ttaactttat cctcatgtac acagatcaca
    19141 tcacaagtat tttcataact catataaaat cacaccctaa attaaaatat aaatcctaaa
    19201 attgtttgaa tagtgtcatt ttcaataata ataaataaac ctaaagctat ataaataata
    19261 gccataatcc aacgactaaa tttctcaaca atttctccaa ttcctggaat attagctaat
    19321 ttttgtgcag taaacaccaa gaagaaaatt aaaattaaaa agacaaacag agtaagtaat
    19381 aaattagtaa cacttaatgt cacaaaatac ggaacaaata aaccaatatt atcggcgcca
    19441 caacttgcta tcgtaacaat tgcaaccgta ccaactaatt tagacaatcc tttttcattc
    19501 aattcttttt tagctctctt ttctccttca caatcatcat aaatagccac tttaattcca
    19561 agataaattg gtattaaacc caataaacct aatatccact tttctggaac ataatttaat
    19621 acaaaagcta aaaacaaact aactaatatt aaaataatag accctaaata ttgaccaaca
    19681 taaatatctc tatattcttt tctagtcttt gctctagcaa aaaatattaa taaaattact
    19741 aataaatcaa ctgctgtagc aatataaaga acagcagcag caacaaccgt ttgaatcata
    19801 atacacctca ttcaaaaata tttttgaatg tattataact tatattttta aataatcata
    19861 ggtgctttat tccaattgct ttattgacgt tgagcctcgg aacccttaac aatcccaaaa
    19921 cttgtcgaat ggtcggctta atagctcacg ctatgccgac attcgtctgc aagtttagtt
    19981 aagggttctt ctcaacgcac aataaatttt ctcgacataa atgcatgtct atgcgtagac
    20041 atggagacac ttcagaatta tggagtgatt acatgagttt aactattttt ctttattcag
    20101 ttttaggaag tttattagca aattatatct acgaaaaatc ttcaaaataa ataacttttt
    20161 cggttctact ttgtacactt tatctacctg gtagacctaa ttgttattgc tttacaggtc
    20221 taaaattcgt cgttataatc tagttaaatc ccgtaagggc gcacttatac gtcggataaa
    20281 tcgacatgtg caaaaacgta atcgaccttc gtcgattttt ttatttcaaa attaaagaaa
    20341 cggcttgaga tattccgagc agttataaaa attaatttgc gttgaatatt gctactacat
    20401 tcttgaaaaa gtgatgtaga tttatagccc ataacttttt tgaattacat cgacgatacg
    20461 gcgtcgaaag aaaaataaat agaccgtatg aaagaaaaag ctacctcact ttatctgggg
    20521 tagcttttat tttttatgcc cttattttga attttaagag ggcattttaa agatttaggg
    20581 gtgattcata tagttttata tctaaaactt atatatgctt ttaaaacgca aatatgagcc
    20641 aaataaatat atgctatttt caaaaacaaa aatttgagca aaaacaataa ctatttttag
    20701 acactgccca tttacatgca aattaaaaat tagcataaaa ttctttaaaa cttccccacg
    20761 tttttctaaa ttcctgtagg gcgtttttat caaaaatcaa gacaagaaga aactcgttca
    20821 cactcgtttc aaaaaaacaa gaaatctaat ctatacacct accgttttcc aaccccctca
    20881 aagcatacaa attaaaaaca aaattattca taatcttact ttcttttaac aaaaacataa
    20941 aaaccataaa tagacaaatt aactatcaaa ggcaataaac agtataaaaa aaccacgaat
    21001 aaatcttcat caacatctaa aataaaaaag aataaaacaa ttaacaaaat actaattaac
    21061 aaacctaaaa gtggcaaact ttttatatat ttttctaaat tttcattcat aaaatagact
    21121 cctttcaaaa atatgtttat aaatatatta aaataaatat tgattttata aagcgcttac
    21181 ttatacaatt aaaatatctt attatcttgg aggtatcaaa tgaaaattat aaaattattt
    21241 tcaataattt ccttgttcct actggtattt agcgcgaatt tttctaatgc ttacgcaaat
    21301 gaagaacaaa aaagttcttt actagaaaat caaaaagaaa aattgaaaag caaaaacatc
    21361 gaagtatcac aaatgaccaa gaaagaaata agttttctag aacaattgca aaataaaaat
    21421 gaagatatgc aaaaattcga aaagcaaatg aaaaaagaag gatttaaaaa aataaagcta
    21481 gaagacaaaa attctaaatt aaaatatcta gctacagaag caaatgataa aaatgcatat
    21541 ggctacatag ctaataacgc ttataaaaat gaaaaaacaa aagaaattgt agtttctgaa
    21601 acaatatatg ataactacaa caaaaaaatc acaaaattca ttgccgaaaa aagaagtatg
    21661 actgaaaaca aagagggaaa aatacttatt aacaaaaatt acgttgaata taaggctgaa
    21721 aaagttgata aaaacagacc ggtaacatat gcaggattca aatggaacgg caaagcattc
    21781 gcttgtagta tggctggact ttatgcatgt gctcactact gtggagtatg ggcaatcgta
    21841 aatccaatag ccggcggtgt atgtgaagca gtttgcggaa ctgcatttgc agctggatgc
    21901 tctgtaggtt gattttattc caattgtttt attgacgttg agcctcggaa cccttaacaa
    21961 tcccaaaact tgtcgaatgg tcggcttaat agctcacgct atgccgacat tcgtctgcaa
    22021 gtttagttaa gggttcttct caacatcaat aaattttttc ggcataaata cgatgttcct
    22081 tatttatcct cataaaaaac aatagctgaa atatataacc aattactgtg tgtttgaatt
    22141 tctaatacat gaatatcatt ctttaaaaac ctattaactt gtttatctaa ttgacgatga
    22201 gtaaaagtag cgaaagtttt aatcttcatg atatctctcc ttttataaaa atagcaatcc
    22261 ttattacaat attaaacact tttattttgg attttaagag gcattttgaa gacttagagg
    22321 caaatcatat aggttttgta cttaaaaatc tatacagtct cttaaaacgc aaatatgagc
    22381 caaataaata tatgctaatt tcacaaacaa aaatttcagc aaaatcagtg actaattttt
    22441 tagatactgc ccatttacat gcaaatttaa aaattagcat aaaatacttt aaaacttccc
    22501 catgtttttc taaattcctg cagggctttt cttatcaaaa acttagaaat tttaatttaa
    22561 ctctaaaatc tccgtaagag cataagggaa atttgctatc attcaaaaat gatagatctg
    22621 gcaaggccag acattccaag ggttttaagt tattttaaag tgatatcata caaagctgta
    22681 gtgtcacact tttgtgacac tacatacagc atttgtcaca aaaataagac agcacttttt
    22741 tacagaaaaa caataaaaaa agacatcagt tatcactaat gtcttaaata ataattttgc
    22801 ttttcgaaat tccaaattgc ggtaattgaa tgtgcttttt ttcttcgtct gtcgttttat
    22861 cttcatcact tgtattaatc aaattaccat cttcggcatc gtctaagttt aaaattttat
    22921 gcttttgttt aagcaatcca ccataactta acatacgttt tcgatacaaa cctttttcta
    22981 aatcacttac aatttcttga tttttttcgt cgtcatcagt taaaaagtca gatgatttaa
    23041 cggaatattt tgatgtctct tcgagtgtta taaaatcatt tgaattattg attaaagata
    23101 ttatattgtt tcatgttttt acggcgcata taaagggcat gtgtttcttc aagttcagtt
    23161 agaattgttt gcattaaata agcttgcatt gacttgattg tttccttttg gcctttaact
    23221 cccctatcat gtatagcttt tttaagtctt tttaaagaag ttaatatttc atcctcaatg
    23281 tcctctaaca tgtaatgcat atcttcatgc cttgaattaa atgatttttt tgctttaaga
    23341 ataacagcct ttatgatttc taaatctcta taatcatatt ttaataaata attagttagt
    23401 tgttctggga attcttgcaa tagcatttct ttatcatcaa aattatgtgt aaattgattt
    23461 gaatgatttg aatgattact aatttcattt ttgtacttta tatcattcaa gtcattcata
    23521 tcattattct cagtatcatt aaagtcaatg tcattaaagt cagtatcatt agtgttcgat
    23581 tttcgaactt ctggacgttc gattttcgaa cttctggaag ttcgattttc gaacttctgg
    23641 acgttcgatt ttcgaacttc cttctcgccg taaggttcaa catcgttttc ttctttttct
    23701 attttgtaaa tatcacgttc tgtgacaata ggtttcatta aatatagaat atttggttta
    23761 tttaaaccac gtcgtttttg aatgagtaga ccatcgtttt ctaacccttt ttttattttt
    23821 gttaactttt cttttttaca atttaagatt tccattagct tttcatttga ataaacaaag
    23881 taaatgttac catcttcatc aacccagcta tttttaatag ataaatttaa gcgatcacgt
    23941 aagatagcat aggctatttt catatcatta gttagatttt tataattttc actggtaaag
    24001 aatactttag ggatttgata aaatctttct ttgtaatttt cttgcactgt aaaatattga
    24061 ttttgcatga caaaaaacct ctttccatat tttagtttgg taagaggtaa taaaacgttt
    24121 ttatttagct ttacatttat ttaatgattt aggtgcttgc actaagatat tattcattat
    24181 ataatacaag tatcgaaaat tatataaata aacagtttct aaacgtttta ttaccaaacc
    24241 ccgactatta ccagtagttg gggtttttgt tatattaagt ttattatagc actttaaata
    24301 aacttataaa agggaaaata tagctttatc aagggtttat aaacccttga taaatatcat
    24361 aaacctttca taaacccttg ataaaaaggt tgatggatgt ttatttttat ttattaatca
    24421 ctttattatt aagcattata agcttataat attttatcaa gggtttataa acattttata
    24481 aagggttgat gatatgaaaa gtgtgaaaaa gttgagtgaa gaattagggg ttagtaagca
    24541 aacgattttt aataatatta agcgattgaa tatagagaca ataaaacagg aaaacacttc
    24601 gtttattaaa gaagataccg atatagaaaa aatcattcaa agagtaaatg aaaataaaaa
    24661 gaaatatggt tttgaaagta ctactgaaga caaacaaaaa aaagggtcgg ataatattaa
    24721 ttttgaatcg aaaagcgatg ctcaaatagt agaaatcctt aaaaatcaga ttgatacttt
    24781 aaataatcaa attgaaaaac aagaaagtcg tcatgaaaca acaattgaat tttacagaaa
    24841 agagttgcaa gaaagatcaa aattgcttga aaatcagcaa gttctggcat tagagagtaa
    24901 taaaaagatt caaaaattag aaaatcaatt agaaaaagaa aaacacctta attatccctt
    24961 tgatacatct actaacacta gacaaaacgt tgatgcacaa gaaaaaacat atactactaa
    25021 tcctgtaaat attaacagag atcaggaaga aactaaagaa acagagattc aatataagga
    25081 tatatctgga agtcaaagcg acgaaagtac acaaggtgaa gaagcaaaaa aagaagacgt
    25141 tccagctaat ctaaatgaca atgatagtga tatagaagaa aagagtgaag aaacggaacc
    25201 taaaaagggg ttttggagtc gtttgtttgg tagctaaaat aattgattag gcactaaaag
    25261 ttataaaatt ttagtgtctt ttatatagtg agaacttctg gtaatcatcg attatgtaaa
    25321 ctaaagtatt tcaaataatt aactgtatta atactctcat catgattgcg ttataaacgt
    25381 tcgttattga gacaaaattt aatagtacta ctacacaaaa agagagtgcg aattcgcact
    25441 ctctttttgt gataaatgaa tggttaagaa aataattcat ccacagttgt atcaaacaat
    25501 cttgccaact taaatgctaa tgtcaatgta ggatcatatt tattgttttc tattgcatta
    25561 atagtttgcc tagacacttt taattcttta cttaaagttt cttgagaaat tcctttttgt
    25621 tttctatatt ctctaattct atttttcatc aatttaacct ttagatgtat attttttatt
    25681 tgtagtatag taattaaaca gcataagaaa tagtgctaca attataaaga aaatttctgg
    25741 atattgagaa aaccaagatc cttcaatact tggtgacaaa cctgtaaatt taagcactag
    25801 tgtaaataac atacaatata caatccaaat aaaactttta gccagtattt caataaacat
    25861 tttacgttgt ctttcatcgt atcgatcttg ttgtcctttt ttatctaatg tttctgaagg
    25921 taaatatttg ttagttatag ccgtccataa acaagaaaaa attaaaataa taataaaagg
    25981 aattaaattc attataacac ctcataaatg taaaaagtat ttgacattta tgagtgtaaa
    26041 tatttttgat acaaatgtca aatacttttt acattataat atattttaaa acaccttatt
    26101 agtaaaacaa ttactatata gaaagctgcg aactcgtact cttttttctt gtataattat
    26161 taaaatctca attcaataat atgttatgga atttgagaca ctgtgagaga cgctcatttg
    26221 cattgacaat caatttatca agataatccc ttatcatgtt taattctata aactgtttgt
    26281 cttgtgatat taacttcttt cgcaatctta ctaatcgctt tgccttcttc taacatttcc
    26341 accacgcgat gataaataac acgtttctgt gggtctttag catttggtga ataaagtaaa
    26401 gggcgccctt tatatacgcc tttttccttc gcaacttgaa tcccttgcgc ttgtcgacgt
    26461 ttactttcat ttctctcttg ttctgaaacc attgctaata tttgaatgat taaatctttc
    26521 ataaacttat ccagtaatgg attgccaatt acttcattca tcataggtaa gctggtaatc
    26581 attaactgaa cgtctttttc ttttaaataa ttcacagttt caataatttc atcatagtta
    26641 cgtcctaaac gatcaataga ttccacaacg aatcgatctc ccattctgac aaaattgagt
    26701 gcttcttgaa atacaggtct attttccact gactttcccg actgtttctc tgtaaagatt
    26761 ttctccacac caaacgtctt taaattatcc aattgtcttt ctaaattttg atctatcgat
    26821 gatactctcg cataacctat aatcattcat cttcactcca taataaatat acaccctaat
    26881 catacgtttt aattgttata atttcaacaa ttctttttgt atggttaggg tgtactcaaa
    26941 gtgtacatat ctataattaa aacttactaa aaataaatat agattttttc tttgtaacag
    27001 aaccgttcat ttgaaggtca tctctatcat aaatatttaa attaactaaa aattttaatc
    27061 atctgtttaa tacttatgaa atgtatttac ggtaggtatt aaaattgatg aaatttatat
    27121 aagtgctttc aatgaaaatg accgtttatt tatcctcctg atttaagg
//
