LOCUS       NZ_CP029779             9080 bp    DNA     circular CON 08-JAN-2024
DEFINITION  Klebsiella pneumoniae strain WCHKP020034 plasmid p1_020034, complete
            sequence.
ACCESSION   NZ_CP029779
VERSION     NZ_CP029779.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN07235708
            Assembly: GCF_002811335.3
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 9080)
  AUTHORS   Liu,L., Long,H., Feng,Y. and Zong,Z.
  TITLE     The complete genome of Klebsiella pneumoniae strain WCHKP020034
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9080)
  AUTHORS   Liu,L., Long,H., Feng,Y. and Zong,Z.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2018) Center of Infectious Diseases, West China
            Hospital, Sichuan University, Guoxuexiang 37, Chengdu, Sichuan
            610041, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.6
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200.0x
            Sequencing Technology             :: Illumina HiSeq; MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/08/2024 03:39:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,718
            CDSs (total)                      :: 5,595
            Genes (coding)                    :: 5,467
            CDSs (with protein)               :: 5,467
            Genes (RNA)                       :: 123
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 12
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 48 of 128
            Pseudo Genes (incomplete)         :: 80 of 128
            Pseudo Genes (internal stop)      :: 22 of 128
            Pseudo Genes (multiple problems)  :: 18 of 128
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP029779.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..9080
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="WCHKP020034"
                     /host="Homo sapiens"
                     /db_xref="taxon:573"
                     /plasmid="p1_020034"
                     /geo_loc_name="China: Sichuan, Chengdu"
                     /collection_date="2017"
     gene            complement(join(7230..9080,1..60))
                     /locus_tag="CEA73_RS29380"
                     /old_locus_tag="CEA73_29425"
     CDS             complement(join(7230..9080,1..60))
                     /locus_tag="CEA73_RS29380"
                     /old_locus_tag="CEA73_29425"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="WP_100792573.1"
                     /translation="MKNNGFRYDINGLRAYAVILVVLFHFGVTGFSAGFVGVDIFFVIS
                     GFLMTKIISDRLLDNSFSLMDFISSRAIRILPALLVMTLVVCLIGWFLLEPSEYKKYGA
                     YAASSIVFSSNILYWKKTGDYFSTDSHDIPLLHTWSLSVEWQFYLLLPIFLWLVTRVKN
                     RKEVIQVSIVFLFIISFLLLCFFSENNQTFSFFMLPMRAWEMAAGGLVYLIFNNVNFNK
                     LNPLGLILILVSLCTASRGYSWPGYLTLLPVIGTMLVLIARNGNSIFFRLKAIQKVGDW
                     SYSIYLWHWPIVFFISYLDIKNTYSSFFGVILSIILGMISFKFIETPTRKLSTKLGFVK
                     SLIYISISVVILFLIYSLIFYKQGFISRADGVFIAKTENIKMPRTNDGWCFYDFSNDSS
                     LVVGSKKAQECFLGSSSKTARKALLIGDSFAGHNSPFWDYIGKDLNISVQGVSTNWCYP
                     SLNGDYTGRKGSVEYKQCLLNRGFLINNFKNYDYIILAGMWSSVFDKNQIENLNELTKF
                     LVKNNKKVIIMDEPYAFDKKIADIYKRKLWLDQRFSINPYLDNDREKGQVNLSNVIGDI
                     LKDNHVFLISRESLFSKDQVTSQNIPYSLDGVHISVYGSIESSKFFEKQHRYKDLIHFM
                     K"
                     /name="acyltransferase family protein"
     gene            292..1506
                     /locus_tag="CEA73_RS29330"
                     /old_locus_tag="CEA73_29375"
     CDS             292..1506
                     /locus_tag="CEA73_RS29330"
                     /old_locus_tag="CEA73_29375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558215.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="WP_185762108.1"
                     /translation="MIDVLGPEKRRRRSVQEKIAIVQQSFEHGMTVSLVARQHGVVLWR
                     KQYQEGSLTAVAAGEQVVPASELASAMKQIKELQRLLGKKTMENELLKEAVEYGRQKKV
                     DSARALVAGGWRISLVSRCLRVSRAQLHAMARGAKNWQDRRRRRKPDDTDVLARIDTVI
                     GDLPTYGYRRVWALLRRQSESDDMAVINAKRVYRIMRQNALLLERKPVIPPSKRAHTGK
                     VAVGESNQRWCSDGFGFSCDNGEKLRVTFALDCCYREALHWAASNGGYDSETVQDVILG
                     AVERRFGSSLPSSPVEWLTDNGSAYRSHQTRQFARMVGLEPEHTAVRSPESNGMAESFV
                     KTLKRDYISIMPKPDGLTAVKNLAEAFEHYNEWHPHSALGYRSPREYLRRRVSNGLGDK
                     KCLEI"
                     /name="IS3 family transposase"
     gene            1655..1771
                     /locus_tag="CEA73_RS30025"
     CDS             1655..1771
                     /locus_tag="CEA73_RS30025"
                     /inference="COORDINATES: protein motif:HMM:NF033853.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small membrane protein"
                     /protein_id="WP_142293809.1"
                     /translation="MDWISLAIAIALLVVAVYSGISYFREKKAISRVFRSKR"
                     /name="small membrane protein"
     gene            2824..3045
                     /locus_tag="CEA73_RS29335"
                     /old_locus_tag="CEA73_29380"
     CDS             2824..3045
                     /locus_tag="CEA73_RS29335"
                     /old_locus_tag="CEA73_29380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016162091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_100792582.1"
                     /translation="MEFDTAAELAALQEQTRRIRQVRYRPSRLDRYTGELLSLYQAGAS
                     AAELQRWLRARRIKVVLSTVTRWLEKNG"
                     /name="hypothetical protein"
     gene            3038..3925
                     /locus_tag="CEA73_RS29340"
                     /old_locus_tag="CEA73_29385"
     CDS             3038..3925
                     /locus_tag="CEA73_RS29340"
                     /old_locus_tag="CEA73_29385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016947203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="WP_110976024.1"
                     /translation="MAKFASAARQSAGVIKTLQGGILRSVGTVRNYEQGLTRVAEWMKA
                     NRINHGDLRTLTPAQAITYLEQRGEQVGQKTLDMERQAIQAMMIHVTQTLPAGEHLPVV
                     KSEQAQILSSRAYSPDQVALIAAAQQPANALATAIALAAGLRAHELLTLAPRQERAPDP
                     RPAADSKFAGREGVIYTVQGKGGLVREVLIPSPLAERLEHVRLASPVRVTDRGVFYQSQ
                     YAIGGGQRWSNAFSAASMRTLGWSRGAHGVRHSYAQQRMQELQKLGLVRDMALRTVSQE
                     MGHFRPEITETYLR"
                     /name="site-specific integrase"
     gene            3922..4620
                     /locus_tag="CEA73_RS29345"
                     /old_locus_tag="CEA73_29390"
     CDS             3922..4620
                     /locus_tag="CEA73_RS29345"
                     /old_locus_tag="CEA73_29390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016947204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_100792576.1"
                     /translation="MTRTFILLCTGVFAIAYALYELKHMGVYYPDASNPQLFTGWKAVT
                     ELGPAILATGIAATAFSLWLFILFFRSSESRRIQSETDRYKQALREAEEAHRARQNTLI
                     QNHNLEIAALRSHYSGAEDVLREAFAQKESLLLQAVQNARKEARKELEEQREALNQRES
                     ILQKKELALETTLEKARKYVAGERHNTVLARLEAEKAEERRRNACATAERRRRKLEKLQ
                     TTDGTAGQKH"
                     /name="hypothetical protein"
     gene            complement(4627..5031)
                     /locus_tag="CEA73_RS29350"
                     /old_locus_tag="CEA73_29395"
     CDS             complement(4627..5031)
                     /locus_tag="CEA73_RS29350"
                     /old_locus_tag="CEA73_29395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016162088.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_100792577.1"
                     /translation="MAKVSISEAARLTGKSRTTLHRLIKAGELSTCRGERNAKILETSE
                     LLRVFGAFAPVPVEQRGEQVSGQRDTVTSDHNEQVIYTLKQEIKHLNTLLASKDSHIDS
                     LKQAMLLLENREDQRQNTTRPRAWWRFWQS"
                     /name="helix-turn-helix domain-containing protein"
     gene            complement(5031..5222)
                     /locus_tag="CEA73_RS29355"
                     /old_locus_tag="CEA73_29400"
     CDS             complement(5031..5222)
                     /locus_tag="CEA73_RS29355"
                     /old_locus_tag="CEA73_29400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_016947206.1"
                     /translation="MTKQQKTALNMAKFIQNQSLLLLEKLNELDLDAEADLCEKLHDDA
                     EHLFRTLSLRLDALQEGD"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            5641..5754
                     /locus_tag="CEA73_RS30525"
                     /old_locus_tag="CEA73_29410"
     CDS             5641..5754
                     /locus_tag="CEA73_RS30525"
                     /old_locus_tag="CEA73_29410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_032634168.1"
                     /translation="MHEPPVQSDCCALSGNYRLESNPERHAKAPLAAATGN"
                     /name="hypothetical protein"
     gene            complement(6340..7028)
                     /locus_tag="CEA73_RS29370"
                     /old_locus_tag="CEA73_29415"
     CDS             complement(join(6340..6779,6779..7028))
                     /locus_tag="CEA73_RS29370"
                     /old_locus_tag="CEA73_29415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001743396.1"
                     /ribosomal_slippage=""
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
                     /protein_id="WP_228711441.1"
                     /translation="MASVSISCPSCSATDGVVRNGKSTAGHQRYLCSHCRKTWQLQFTY
                     TASQPGTHQKIIDMAMNGVGCRATARIMGVGLNTILRHFKKLRPQSVTSRIQPGSDVIL
                     CAEMDEQWGYVGAKSRQRWLFYAYDRLRKTVVAHVFGERTMATLGRLMSLLSPFDVVIW
                     MTDGWPLYESRLKGKLHVISKRYTQRIERLNLNLRQHLARKSLSFSKSVELHDKVVGHY
                     LNIKHYQ"
                     /name="IS1 family transposase"
     Typing          5271..5754
                     /name="ColRNAI_rep_cluster_1987"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="91.17"
                     /coverage="92.0"
                     /evalue="0.0"
ORIGIN
        1 caaaataact gcataggctc ttaagccatt aatgtcgtat ctaaacccat tattcttcat
       61 acaattaacg ccatcaaaag atttaatcga ttataaatta atactatatt aaagtaatat
      121 ttaaattttt ataaaattaa aacaatacac atttcgcgca cctctcaaac gccataatcc
      181 ataaaatact acaaatacta ctccttccat tatagactcg tcccatgaat ggtatcactt
      241 aagttagtga tagtcttaat actagttttt agactagtca ctggagtccg gatgattgat
      301 gttttaggtc cagagaaacg cagacggaga agcgtccagg aaaaaatcgc cattgttcag
      361 cagagctttg aacacggtat gactgtgtct ctggttgccc ggcagcatgg tgttgtcctg
      421 tggcgtaagc agtatcagga aggcagcctt accgccgttg ctgctggaga acaggttgta
      481 cccgcatcgg agctggcgtc tgcgatgaag caaattaaag agctacagcg cctgctgggc
      541 aagaaaacca tggaaaacga gctgctaaaa gaagccgttg aatatggccg acaaaaaaaa
      601 gtggatagcg cacgtgccct tgttgccgga ggatggcgaa taagccttgt cagtcgttgc
      661 ctacgggtct cacgtgcgca actgcatgcc atggcccgtg gggcgaagaa ctggcaggat
      721 cgccgacgca ggcgcaagcc tgatgatact gacgtgctgg cccgtatcga taccgttatc
      781 ggcgatctgc ctacgtatgg ttatcgtcgg gtgtgggcac tgctgcgcag acaatctgaa
      841 tctgacgaca tggccgttat caatgccaaa cgcgtatacc ggatcatgcg gcagaatgcg
      901 ctgctgcttg agcgtaaacc tgtaataccg ccctcgaaac gggcgcatac agggaaagtg
      961 gccgtcgggg aaagtaacca gaggtggtgc tctgacggct tcgggttcag ctgtgataat
     1021 ggcgaaaaac tgcgggtcac gttcgcactg gactgctgct atcgtgaagc actgcactgg
     1081 gcggccagta acggtggata tgacagcgaa accgtacagg acgtgattct gggtgcggtg
     1141 gaacgacgct tcggcagcag cctgccgtca tcccccgttg agtggctgac ggataacggt
     1201 tcggcctacc ggtctcacca gacgcgtcag ttcgccagaa tggtaggact ggagcctgaa
     1261 catacggcgg tacgcagccc ggaaagcaac gggatggcag agagcttcgt caaaacgctg
     1321 aagcgcgatt acatcagcat catgccgaag cccgacgggt taacagcggt aaagaacctt
     1381 gcggaagcct tcgaacatta caacgaatgg catccgcata gtgcactggg atatcgttcg
     1441 ccacgggaat atctgcggcg gcgagtcagt aatgggttag gtgataaaaa gtgtctggaa
     1501 atataagggc caatccaacg tcttcttacg tgtactgaac aatgcgtcct caggaaccat
     1561 tagctcaaag caataagtgt aatgaaaaaa gaatgaaaac cacttacaat aactaatcaa
     1621 aacaggctgt ttttattaaa ttaatcaggc atttatggac tggatttcac ttgctatcgc
     1681 cattgctcta cttgttgtag ctgtctactc aggaatctca tacttcagag aaaaaaaagc
     1741 aatcagtcgt gtatttagga gtaagcgata gcgccctatt taccataatc ccttcttacg
     1801 cgcaccgcga aaacggcctc agggcgtttc tggcaggaaa ccggtaaaac aggcaacaaa
     1861 ccacccgaaa acccgccaga aacgcacctg atttatttta cgcatatgca tggctatgca
     1921 caccaccgca tagccggtga tttcggtcga gaaaagggtt ctggacgtta aaagcataaa
     1981 agaacgggcc atccaggccc gtcaaatgag gacaacactg taaaaggacc gtcgcacctg
     2041 gtgcggtgcc ggcgacaaga aaaaggtagc tcatatcagc ccctcaccgg agaaaaatat
     2101 ttcctggcca cctcaaccgc cacacgctgt gttcccgtta actcgcgcag ataacgcagg
     2161 aacatcctgt tttcctctgc atgcgcctcc tcactgccct gtgcgtggta ttccactatc
     2221 gcgttcacca cggactcacc gacctgcatc gtctgacctc atctgcactt tcatcacacc
     2281 gtttcagatc ccgcctcctc gccatgatgt gaaacggtga ccgggcaggc caattttttg
     2341 tctgtccggt caccgttggc ggggtccggg gcggtcagtc ccggtgtttt ttattccgcc
     2401 aaatcagcac ctgcgacacc cgctatgtac gacgcataaa atgcgcctgt acatagcggg
     2461 aatcgctatt gcgcgaggta aggcgcaaca tttaaaaaac aacattcaca cgcacgaaaa
     2521 acctggctag tatttagtca aaccatgagc cgtgcactct gacgcaccct gtgctccggc
     2581 agcaggtaaa acagccgggt ccctccgggg atactgtacc gggcagccca atccgagaac
     2641 actgagacaa cagcccaaat ctgtcaggcc cacaaacggg ccacgcgcct cccacgctaa
     2701 agggacgtca tttttactac agccgcgagc agtccgggct taaccacgat acggtttaaa
     2761 cgagggcgaa tcggccagtg ccgcagtgga tttccactga tgttcttaca caccggagta
     2821 cagatggaat ttgataccgc tgccgaactg gccgccctgc aggagcaaac ccgccgtata
     2881 cgccaggtcc gctaccgccc atcccgcctc gaccgctata ccggcgaact gctgagtctg
     2941 taccaggccg gggccagtgc agctgagctg caacgctggc tccgggccag acgaatcaaa
     3001 gtggtgctct caaccgtcac ccgctggctg gaaaaaaatg gctaaattcg ccagcgctgc
     3061 ccgccagtcg gctggcgtga taaaaaccct ccagggcggt attttgcgct ctgtcggcac
     3121 ggtccggaat tatgagcagg gactgacccg cgtcgcagag tggatgaaag ccaaccggat
     3181 taatcacggc gatttacgca cactgacacc ggcgcaggcc atcacctacc tggagcagcg
     3241 cggggagcag gtcggccaga aaacgctcga tatggagcgc caggccatcc aggccatgat
     3301 gatccacgtg acgcagaccc tccctgccgg cgaacacctg ccggtggtga aatcggagca
     3361 ggcacagatc ctgagcagcc gggcctacag cccggaccag gtagccctga ttgccgcagc
     3421 acaacagccc gccaacgctc tggccaccgc gattgctctg gccgccggat tacgcgccca
     3481 tgaactgctg accctcgcgc cccgccagga gcgtgcaccg gatccccgtc cggcagcgga
     3541 cagtaaattt gccggtcggg agggtgtgat ttacaccgtt cagggcaaag gcggcctggt
     3601 cagggaagtc ctgataccgt cccccctggc tgaacgtctg gagcatgtca ggctggccag
     3661 cccggtccgg gtgaccgatc gcggcgtgtt ttaccagagt cagtacgcca ttggcggagg
     3721 acagcgctgg tcgaacgctt tcagtgccgc ctccatgcgt accctgggct ggtcacgggg
     3781 ggcacacggc gtgcgtcaca gctacgccca gcaacggatg caggagctgc aaaaactcgg
     3841 tctggttcgt gatatggccc tgcgcaccgt cagccaggaa atgggccatt ttcgtccgga
     3901 aatcacggag acatacctgc gatgacaaga acgtttattt tattgtgtac cggtgttttc
     3961 gccatcgcgt acgccctgta tgagctgaaa catatgggcg tttactatcc ggatgccagc
     4021 aatccgcagc tgttcactgg ctggaaggcg gtcaccgaac tcggtcccgc aatcctggca
     4081 acggggatcg cagccacagc gttctcgctg tggctgttca ttttgttttt cagaagctca
     4141 gagtcccggc ggatacagag cgagacagac aggtataagc aggctctgag ggaggcagaa
     4201 gaggctcaca gagccagaca aaataccctt attcagaatc acaatctgga gatagcggcc
     4261 ctgcgaagcc actacagtgg tgctgaggat gtactgcggg aagcgtttgc gcaaaaagaa
     4321 agcctcttgc ttcaggcggt gcagaatgcc cggaaagaag ccagaaagga gctggaagaa
     4381 cagagggagg cactgaatca gcgcgaatcc atcctgcaga aaaaggagct ggcgctggaa
     4441 acaaccctgg agaaggcccg gaaatatgtg gccggggagc ggcataacac cgtgctggcc
     4501 cgtctggaag cagagaaagc agaggaaaga cggagaaatg cctgcgcgac ggcggaacgg
     4561 cgcagacgga aactggaaaa actccagacc actgacggaa cagcagggca aaaacactga
     4621 ggcatttcag gactgccaga aacgccacca ggcacggggc cgggtcgtgt tctgccgctg
     4681 atcttcccgg ttctccagca acaacatcgc ctgtttcagg ctgtcgatat gtgaatcttt
     4741 tgaggcaaga agggtgttca ggtgtttaat ttcctgtttc agagtataaa tgacctgttc
     4801 attatggtca gaagtgactg tgtcacgctg tccactgacc tgttcacccc tctgttcaac
     4861 gggtacaggc gcaaaggcac caaacacccg caaaagctct gaagtctcga gaattttcgc
     4921 attccgttca ccccgacagg tggacagttc accggcttta attaacctgt gcagggttgt
     4981 cctgctctta cccgtcaggc gtgctgcctc actgatcgac actttcgcca tcagtcaccc
     5041 tcctgtagtg catccagtct gagggacagt gtacggaaaa gatgctccgc atcatcgtgg
     5101 agtttctcac aaaggtcagc ctccgcatcg agatcaagct cgttaagctt ctccagcagg
     5161 agcagggact gattctggat gaatttagcc atattcaggg cagttttctg ttgtttcgtc
     5221 ataaggggcc tcagagcgtc agtgctcagt gtaaaacctg tctcttttcc gcttcctcgc
     5281 tcactcagtc gctacgctcc tgccgttcgg ctgcggcgag cggacgggac acacagaaga
     5341 gtgaagagtc atcgctataa ccaggaagag aagagcctgt ggaaaaggcc acggcgttgc
     5401 cgtttttcca taggctccgc ccccctgaca agcatcacag aatctgacgc tcaaatcagt
     5461 ggtggcgaaa cccgacagga ctataaagat accaggcgtt tccccctggt ggctccctcg
     5521 tgcgctctcc tgttcctgcc tttcggttta ccggtgtcat tccgctgtta tggccgcgtt
     5581 tatctcattc cacgcctgac actcagttcc gggaaggcag ttcgctccaa gctggactgt
     5641 atgcacgaac cccccgttca gtccgactgc tgcgccttat ccggtaacta tcgtcttgag
     5701 tccaacccgg aaagacatgc aaaagcgcca ctggcagcag ccactggtaa ctgatttaga
     5761 ggagatggac ttgaagtcat gcaccggtta aggctaaact aaacgaacag ttttggtgac
     5821 tgcgctcctc taactagcca gttacctcgg ttcaaagagc gccaactctt ggaaccttcg
     5881 aaaaaaccgc cctgcaaggc ggttttttcg tttctagaga aagagattac ccgcagaaaa
     5941 agatgatctc aagaagatcc ttcgtcagta gcgtcagcct tccctcagta gtaagctgca
     6001 gtaatgcagc caatctattg atacgtcctt gcacaccacc ttaaggacct cttgctgcgg
     6061 cgagcattgc gtgcaaaaaa tacgcaccat tctcacgggg ggttcggggg attacatccc
     6121 ccgaaccaga cacggtgaat cctctggcgg ggatttcacc gtgtctactg gctgcaaaaa
     6181 agccctctga caaaagaggg ctgttatctg atataggctt gtttagtgcc attcttgcga
     6241 ctagttttta gcctcgccat ataatcgatt gatatataat gttttttgtt ttaaataaca
     6301 acaagtaatc aacaatgaaa cgcgggtaat gactccaact tattgatagt gttttatgtt
     6361 cagataatgc ccgacgactt tgtcatgcag ctccaccgat tttgagaacg acagcgactt
     6421 ccgtgccagg tgctgcctca gattcaggtt aagccgctca attcgctgcg tatatcgctt
     6481 gctgattacg tgcagctttc ccttcaggcg ggattcatac agcggccagc catccgtcat
     6541 ccatatcacc acgtcaaagg gtgacagcag gctcataaga cgccccagcg tcgccatagt
     6601 gcgttcaccg aatacgtgcg caacaaccgt cttccggagc ctgtcatacg cgtaaaacag
     6661 ccagcgctgg cgcgatttag ccccgacata gccccactgt tcgtccattt ccgcgcagag
     6721 gatgacgtca ctgcccggct gtatgcgcga ggttaccgac tgcggcctga gttttttaag
     6781 tgacgtaaaa tcgtgttgag gccaacgccc ataatgcggg cggttgcccg gcatccaaca
     6841 ccattcatgg ccatatcaat gattttctgg tgcgtaccgg gttgagaagc ggtgtaagtg
     6901 aactgcagtt gccatgtttt acggcagtga gagcagagat agcgctgatg tccggcagtg
     6961 cttttgccgt tacgcaccac cccgtcagta gctgaacagg agggacagct gatagaaaca
     7021 gaagccactg gagcacctca aaaacaccat catacactta atcagtaagt tggcagcatc
     7081 accggttgcc gaaactccct caacgttcac catctgccca gagagttttc ccgaaggcag
     7141 tggcgagttt ttaatactta acattgagcc cttaaaaatc taactttcaa tgaatgatta
     7201 aaagttagat taattgtttc gaactaagat tacttcatga aatgaattaa atctttatat
     7261 ctatgctgtt tctcaaaaaa ctttgaagat tcaattgagc cataaactga aatgtgcact
     7321 ccatctaagc tataagggat attttgtgat gtaacctgat ctttggaaaa taagctctct
     7381 cgacttataa gaaaaacatg attgtctttt aatatatccc caataacatt ggataaatta
     7441 acctggcctt tttccctgtc attatcaagg tatggattta tagagaacct ttgatctaac
     7501 cacaacttcc ttttatatat atcagctatt ttcttatcga atgcatatgg ctcatccata
     7561 ataataacct ttttattatt tttcactaaa aacttggtta gttcatttaa gttttcaatc
     7621 tgatttttat caaaaacact agaccacatc ccagcaagga taatataatc ataattttta
     7681 aaattattaa tcaagaatcc cctatttaaa aggcattgct tatactcaac ggaaccttta
     7741 cggcctgtat aatccccgtt aaggcttggg tagcaccaat tagtgctaac tccttgcact
     7801 gatatattta aatcttttcc tatataatcc caaaacggag agttatgtcc agcaaatgaa
     7861 tctccaatca ataaagcttt acgtgcagtt ttagatgatg accctaaaaa acattcttgt
     7921 gctttctttg aaccgacaac caacgatgaa tcgttagaaa aatcataaaa acaccaacca
     7981 tcattagttc ttggcatttt aatattttca gttttagcaa taaaaacacc atcagcccta
     8041 ctaataaatc cttgcttata aaaaataagt gaatatatta aaaacaaaat cactacacta
     8101 atagatatgt atattaaact tttaacgaaa cctaactttg ttgacaactt tcttgttggt
     8161 gtttctataa acttaaaact tatcatccct aaaattatgg aaagaattac accaaaaaaa
     8221 gatgagtatg tgttttttat atctaaatac gaaataaaga atacaatagg ccaatgccat
     8281 aagtatattg aataagacca atccccaact ttttggatag ctttaagacg gaaaaatatt
     8341 gaatttccat ttcttgctat aagaacaagc atggttccaa tcacaggcaa caatgttagg
     8401 taaccaggcc acgaataccc cctagaagca gtgcaaaggc taactaatat taaaatcaac
     8461 cctaatggat tcaacttatt aaaattaaca ttattaaaaa taagataaac caaaccacct
     8521 gctgccattt cccatgcacg catgggcaac ataaaaaatg aaaatgtttg attattttca
     8581 ctaaaaaaac ataaaagcaa aaaagaaatt ataaataaaa aaactataga tacttgaata
     8641 acttcttttc ggttcttaac ccttgttacg agccataaaa agattggtaa caataaatag
     8701 aattgccact ctaccgataa tgaccatgtg tgaagcaaag gaatatcatg tgaatccgtc
     8761 gaaaaataat caccagtttt cttccaatat aatatattgg aagaaaaaac tatacttgat
     8821 gcagcataag ctccatattt tttatattca gatggttcta gtaagaacca acctatcaag
     8881 catacaacaa gagtcatcac caacagtgct ggcaatattc taattgctct ggatgaaata
     8941 aaatccatta gagaaaaact gttatccaac aacctatcag atataatctt tgtcattaaa
     9001 aaacctgaaa tcacaaaaaa aatatcaacg ccaacaaaac ctgctgaaaa tcctgtaaca
     9061 ccaaaatgga aaagcaccac
//
