LOCUS       NZ_CP029665            26984 bp    DNA     circular CON 08-MAY-2024
DEFINITION  Staphylococcus aureus strain AR_0226 plasmid unnamed1, complete
            sequence.
ACCESSION   NZ_CP029665
VERSION     NZ_CP029665.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN04901616
            Assembly: GCF_003203595.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 26984)
  AUTHORS   Benahmed,F.H., Lutgring,J.D., Yoo,B., Machado,M., Brown,A.,
            McAllister,G., Perry,A., Halpin,A.L., Vavikolanu,K., Ott,S.,
            Zhao,X., Tallon,L.J., Sadzewicz,L., Aluvathingal,J., Nadendla,S.,
            Voskania-kordi,A., Simonyan,V., Patel,J. and Shawar,R.M.
  TITLE     FDA/CDC Antimicrobial Resistant Isolate Bank Genome Sequencing
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 26984)
  AUTHORS   Benahmed,F.H., Lutgring,J.D., Yoo,B., Machado,M., Brown,A.,
            McAllister,G., Perry,A., Halpin,A.L., Vavikolanu,K., Ott,S.,
            Zhao,X., Tallon,L.J., Sadzewicz,L., Aluvathingal,J., Nadendla,S.,
            Voskania-kordi,A., Simonyan,V., Patel,J. and Shawar,R.M.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-MAY-2018) Center for Devices and Radiological Health,
            US Food and Drug Administration, 10903 New Hampshire Avenue, Silver
            Spring, MD 20993-0002, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: canu v. 1.4
            Genome Coverage                   :: 22.28x
            Sequencing Technology             :: Pacbio; Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003203595.1-RS_2024_05_08
            Annotation Date                   :: 05/08/2024 03:43:06
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,925
            CDSs (total)                      :: 2,843
            Genes (coding)                    :: 2,755
            CDSs (with protein)               :: 2,755
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 49 of 88
            Pseudo Genes (incomplete)         :: 43 of 88
            Pseudo Genes (internal stop)      :: 17 of 88
            Pseudo Genes (multiple problems)  :: 20 of 88
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP029665.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..26984
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="AR_0226"
                     /db_xref="taxon:1280"
                     /plasmid="unnamed1"
     gene            complement(7..888)
                     /locus_tag="CSB82_RS15115"
                     /old_locus_tag="CSB82_2773"
                     /pseudo=""
     CDS             complement(7..888)
                     /locus_tag="CSB82_RS15115"
                     /old_locus_tag="CSB82_2773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015581923.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0000155 - phosphorelay sensor kinase activity [Evidence
                     IEA]; GO:0004673 - protein histidine kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /name="sensor histidine kinase"
     gene            complement(885..>1262)
                     /locus_tag="CSB82_RS15120"
                     /old_locus_tag="CSB82_2775"
                     /pseudo=""
     CDS             complement(885..>1262)
                     /locus_tag="CSB82_RS15120"
                     /old_locus_tag="CSB82_2775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019834602.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]; GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /name="response regulator transcription factor"
     gene            complement(1320..1994)
                     /locus_tag="CSB82_RS15125"
                     /old_locus_tag="CSB82_2776"
     CDS             complement(1320..1994)
                     /locus_tag="CSB82_RS15125"
                     /old_locus_tag="CSB82_2776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="WP_001105960.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            2468..3934
                     /gene="msr(A)"
                     /locus_tag="CSB82_RS15130"
                     /old_locus_tag="CSB82_2777"
     ARG             2469..3931
                     /name="msr(A)"
                     /gene="msr(A)"
                     /gene_name="ABC-F type ribosomal protection protein Msr(A)"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE/STREPTOGRAMIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            4033..4932
                     /locus_tag="CSB82_RS15135"
                     /old_locus_tag="CSB82_2778"
     CDS             4033..4932
                     /locus_tag="CSB82_RS15135"
                     /old_locus_tag="CSB82_2778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mph(C) family macrolide 2'-phosphotransferase"
                     /protein_id="WP_000196697.1"
                     /translation="MTRHNEIIKCAEKYQLHIQPQTISLNESGLDFQVAFGKDKHGVEW
                     VLRLPRRPDVYKRTKPEKQTVDFLQKNVSFEIPKWKVHAKDLIAYPKLTGKPAATIDPE
                     IQNYVWEIEHKPLPENFINTLAETLVDLHNIPEENINVQHINIKTIQEIKNDFQRRMNK
                     VKETYGVSDELWNRWKQWLENDELWPRHATMIHGDLHPGHIMVDNQANVTGLIDWTEAT
                     HSDPSMDFIGHHRVFDDEGLEQLITAYGKAGGEIWPRMKEHIIELNAVFPMFIAEFAME
                     SGESAYETMALKELGMKE"
                     /name="Mph(C) family macrolide 2'-phosphotransferase"
     gene            5418..6026
                     /locus_tag="CSB82_RS15140"
                     /old_locus_tag="CSB82_2779"
     CDS             5418..6026
                     /locus_tag="CSB82_RS15140"
                     /old_locus_tag="CSB82_2779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002474535.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000583528.1"
                     /translation="MIIGYARVSSIDQNLERQLDNLKTFGVEKIFTEKQSGKSVENRPV
                     FQEALNFVRMGDRFVVESIDRLGRNYDEIIETVNYLKEKDVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRV
                     IYHRVVEMLEEGKAISKIAKEVNITRQTVYRIKHDKGLS"
                     /name="recombinase family protein"
     gene            6272..6610
                     /locus_tag="CSB82_RS15145"
                     /old_locus_tag="CSB82_2780"
     CDS             6272..6610
                     /locus_tag="CSB82_RS15145"
                     /old_locus_tag="CSB82_2780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001049146.1"
                     /translation="MNLIPFIIILIFSCLWTAITNKYLPSETLDKKGQQDRYDERQRKM
                     FIEILAKSFIWIVYCMLFTLVLKFTGLSPSIEGSWFSQYPEIFFIIVALFLMLFNYYTT
                     NKKYTSKG"
                     /name="hypothetical protein"
     gene            6615..6800
                     /locus_tag="CSB82_RS15150"
                     /old_locus_tag="CSB82_2781"
     CDS             6615..6800
                     /locus_tag="CSB82_RS15150"
                     /old_locus_tag="CSB82_2781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011276570.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000797248.1"
                     /translation="MKNRIREYRKQKGISQETLSKELKVSRQTINAIENNKYDPTLTLA
                     FKLARLFDTTVDELFS"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(7027..7770)
                     /locus_tag="CSB82_RS15155"
                     /old_locus_tag="CSB82_2782"
     CDS             complement(7027..7770)
                     /locus_tag="CSB82_RS15155"
                     /old_locus_tag="CSB82_2782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843732.1"
                     /translation="MKSVKKLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESTTEDKQKKGSDNINFESKSDAQIVEILKNQIDTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNTR
                     QNVDAQEKTYTTNPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAKKEDVPANLND
                     NDSDIEEKSEETEPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     gene            8196..9179
                     /locus_tag="CSB82_RS15160"
                     /old_locus_tag="CSB82_2783"
     CDS             8196..9179
                     /locus_tag="CSB82_RS15160"
                     /old_locus_tag="CSB82_2783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_001181107.1"
                     /translation="MQNQYFTVQENYKERFYQIPKVFFTSENYKNLTNDMKIAYAILRD
                     RLNLSIKNSWVDEDGNIYFVYSNEKLMEILNCKKEKLTKIKKGLENDGLLIQKRRGLNK
                     PNILYLMKPIVTERDIYKIEKEENDVEPYGEKEVRKSNVQKFENRTSRSSKIERPEVRK
                     SNTNDTDFNDIDFNDTENNDMNDLNDIKYKNEISNHSNHSNQFTHNFDDKEMLLQEFPE
                     QLTNYLLKYDYRDLEIIKAVILKAKKSFNSRHEDMHYMLEDIEDEILTSLKRLKKAIHD
                     RGVKGQKETIKSMQAYLMQTILTELEETHALYMRRKNMKQYNIFNQ"
                     /name="replication initiator protein A"
     gene            <9199..9488
                     /locus_tag="CSB82_RS15165"
                     /pseudo=""
     CDS             <9199..9488
                     /locus_tag="CSB82_RS15165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009384749.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            10035..10184
                     /locus_tag="CSB82_RS15390"
                     /old_locus_tag="CSB82_2785"
     CDS             10035..10184
                     /locus_tag="CSB82_RS15390"
                     /old_locus_tag="CSB82_2785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000695366.1"
                     /translation="MKIKTFATFTHRQLDKQVNRFLKNDIHVLEIQTHSNWLYISAIVF
                     YEDK"
                     /name="hypothetical protein"
     gene            complement(10352..11044)
                     /locus_tag="CSB82_RS15170"
                     /old_locus_tag="CSB82_2786"
     CDS             complement(10352..11044)
                     /locus_tag="CSB82_RS15170"
                     /old_locus_tag="CSB82_2786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative immunity/bacteriocin fusion bifunctional
                     protein"
                     /protein_id="WP_000691527.1"
                     /translation="MKIIKLFSIISLFLLVFSANFSNAYANEEQKSSLLENQKEKLKSK
                     NIEVSQMTKKEISFLEQLQNKNEDMQKFEKQMKKEGFKKIKLEDKNSKLKYLATEANDK
                     NAYGYIANNAYKNEKTKEIVVSETIYDNYNKKITKFIAEKRSMTENKEGKILINKNYVE
                     YKAEKVDKNRPVTYAGFKWNGKAFACSMAGLYACAHYCGVWAIVNPIAGGVCEAVCGTA
                     FAAGCSVG"
                     /name="putative immunity/bacteriocin fusion bifunctional
                     protein"
     gene            11154..11348
                     /locus_tag="CSB82_RS15175"
                     /old_locus_tag="CSB82_2787"
     CDS             11154..11348
                     /locus_tag="CSB82_RS15175"
                     /old_locus_tag="CSB82_2787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001004925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001004925.1"
                     /translation="MNENLEKYIKSLPLLGLLISILLIVLFFFILDVDEDLFVVFLYCL
                     LPLIVNLSIYGFYVFVKRK"
                     /name="hypothetical protein"
     gene            12464..13081
                     /gene="cadD"
                     /locus_tag="CSB82_RS15180"
                     /old_locus_tag="CSB82_2788"
     ARG             12465..13078
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            13100..13447
                     /locus_tag="CSB82_RS15185"
                     /old_locus_tag="CSB82_2789"
     CDS             13100..13447
                     /locus_tag="CSB82_RS15185"
                     /old_locus_tag="CSB82_2789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119690.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNHEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            13604..13696
                     /locus_tag="CSB82_RS15190"
     CDS             13604..13696
                     /locus_tag="CSB82_RS15190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(13868..14839)
                     /locus_tag="CSB82_RS15195"
                     /old_locus_tag="CSB82_2790"
     CDS             complement(13868..14839)
                     /locus_tag="CSB82_RS15195"
                     /old_locus_tag="CSB82_2790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="WP_000481279.1"
                     /translation="MFNAVVVRKSASNVSYKVEKVDESHLSKGDVLVKVVYSSINYKDM
                     LALQYKGGVIRDYPMIPGIDFAGIVESSSNDKFKEGDNVLVTGYDVGVTHTGGFSEYAQ
                     VPGEWIVPIPQEMSIKESMVYGTAGFTAALSIFELEKYGMNIKSQPEILVSGATGGVGS
                     VAIQILHKIGYENITAIVRKEKQIEIAKKLGAKQVIIIEDDNKPLKKGIFDYFLDTVGS
                     NVTLYGLKRLNYQGVATVCGNVAGNSLNANILPFILRGIKLIGIDSVYVDHNIREDIWS
                     KLANEWNIGNSLLYNEIGFEEFYKTIDQLLKGQHLGRTILKV"
                     /name="oxidoreductase"
     gene            14963..15382
                     /locus_tag="CSB82_RS15200"
     CDS             14963..15382
                     /locus_tag="CSB82_RS15200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418034.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_000418035.1"
                     /translation="MELDNCINYLLSTSQNRVFKHFKSLLSPYNITPAEYGVLNCLINS
                     NLNTPKAIGNTLNLEPSTISGILDKMSKKDLITRQTDNENRRTVLINSTNKAKDLWPTL
                     EKKAYQLNNHYFANLTNEETVVFKKILLKINKTTF"
                     /name="MarR family transcriptional regulator"
     gene            complement(15908..16753)
                     /gene="blaZ"
                     /locus_tag="CSB82_RS15210"
                     /old_locus_tag="CSB82_2793"
     ARG             complement(15912..16753)
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            16860..18617
                     /gene="blaR1"
                     /locus_tag="CSB82_RS15215"
                     /old_locus_tag="CSB82_2794"
     ARG             16861..18614
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.38"
                     /coverage="100.0"
     gene            18607..18987
                     /gene="blaI"
                     /locus_tag="CSB82_RS15220"
                     /old_locus_tag="CSB82_2795"
     ARG             18608..18984
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="98.41"
                     /coverage="100.0"
     gene            19251..19829
                     /locus_tag="CSB82_RS15225"
                     /old_locus_tag="CSB82_2796"
     CDS             19251..19829
                     /locus_tag="CSB82_RS15225"
                     /old_locus_tag="CSB82_2796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690624.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690637.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLNLLKTLYDNGTPI
                     KTIAEQWQVSRTTIYRYLNKLEAKENKNK"
                     /name="recombinase family protein"
     gene            complement(20052..20237)
                     /locus_tag="CSB82_RS15230"
     CDS             complement(20052..20237)
                     /locus_tag="CSB82_RS15230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001037130.1"
                     /translation="MNKLEKWSLVFIIFTFLSSLALLYFKYNFSSVMPVLSLSILTILI
                     LLTSIITVVSVNDEDT"
                     /name="hypothetical protein"
     gene            20499..21173
                     /locus_tag="CSB82_RS15235"
                     /old_locus_tag="CSB82_2797"
     CDS             20499..21173
                     /locus_tag="CSB82_RS15235"
                     /old_locus_tag="CSB82_2797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105991.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(21342..21913)
                     /locus_tag="CSB82_RS15245"
                     /pseudo=""
     CDS             complement(21342..21913)
                     /locus_tag="CSB82_RS15245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /name="HTH domain-containing protein"
     gene            complement(22189..22983)
                     /gene="aph(3')-IIIa"
                     /locus_tag="CSB82_RS15255"
                     /old_locus_tag="CSB82_2799"
     ARG             complement(22193..22983)
                     /name="aph(3')-IIIa"
                     /gene="aph(3')-IIIa"
                     /gene_name="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(23076..23522)
                     /locus_tag="CSB82_RS15260"
                     /old_locus_tag="CSB82_2800"
     CDS             complement(23076..23522)
                     /locus_tag="CSB82_RS15260"
                     /old_locus_tag="CSB82_2800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_031923810.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEAP
                     YLKSYQDDKCVGKVKLRKNWNRYAYIEDIAVCKDFRGQGIGSALINISIEWAKHKNLHG
                     LMLETQDNNLIACKFYHNCGFKIGSVDTMLYANFEKAVFWYLRF"
                     /name="GNAT family N-acetyltransferase"
     gene            complement(23519..>24154)
                     /locus_tag="CSB82_RS15265"
                     /pseudo=""
     CDS             complement(23519..>24154)
                     /locus_tag="CSB82_RS15265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009251744.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /name="aminoglycoside 6-adenylyltransferase"
     gene            complement(24295..24969)
                     /locus_tag="CSB82_RS15270"
                     /old_locus_tag="CSB82_2801"
     CDS             complement(24295..24969)
                     /locus_tag="CSB82_RS15270"
                     /old_locus_tag="CSB82_2801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105956.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(<25026..25202)
                     /locus_tag="CSB82_RS15275"
                     /old_locus_tag="CSB82_2802"
                     /pseudo=""
     CDS             complement(<25026..25202)
                     /locus_tag="CSB82_RS15275"
                     /old_locus_tag="CSB82_2802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499250.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016311 - dephosphorylation [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /name="undecaprenyl-diphosphate phosphatase"
     gene            complement(25216..25953)
                     /locus_tag="CSB82_RS15280"
                     /old_locus_tag="CSB82_2803"
     CDS             complement(25216..25953)
                     /locus_tag="CSB82_RS15280"
                     /old_locus_tag="CSB82_2803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000369394.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="WP_000369394.1"
                     /translation="MDNLLRTEFIKLKRSYMFLISILGTCVAPFMVVVASFISMRTKVP
                     TPNIVFKQLFEEVSLYHMLIIGPPLYGVIIAYLFGREYIEDTLKNLLIIPISRESFLVS
                     KIILLFLWIQTLSVIAWLLTLMLGMLLHFQGLSQSLIIDSFFTFVIGGVLLWILSPPII
                     ILSIYFKNYVPTIVLTIIITLINLMTANSEHRGLFPWAAVGDISRGTLPNTYPFLLSLI
                     IIIVTSIFSVIILFSYFKKTDIS"
                     /name="ABC transporter permease"
     gene            complement(25946..26875)
                     /locus_tag="CSB82_RS15285"
                     /old_locus_tag="CSB82_2804"
     CDS             complement(25946..26875)
                     /locus_tag="CSB82_RS15285"
                     /old_locus_tag="CSB82_2804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000074567.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016887 - ATP hydrolysis activity [Evidence IEA];
                     GO:0042626 - ATPase-coupled transmembrane transporter
                     activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000793446.1"
                     /translation="MKNLNNIIEINNLTKQYGSQIAVNNLSITVESGQIYGFLGRNGAG
                     KTTTIRMLLGLIKPTKGNIKIFEKEFESNKTEILKNIGAMVETPGFYSNLTAKENLTIN
                     AKILGIQKENAIEEVLEIVGLASEKVKLFKNYSLGMKQRLGIARALLHNPELLILDEPT
                     NGLDPIGIKEIRKLIKDLAQSRNITILISSHILSEIEQLVDKVGIIHNGVLLEEIMYED
                     LKKKNRQFISISVSDEEKVACLLETNFGIYDYKIKENGEFKIYSHIDRQQEINRLLVLN
                     NIDVFQMRVIEDNLETYFEDLVGGGTIG"
                     /name="ABC transporter ATP-binding protein"
     ARG             4034..4929
                     /name="mph(C)"
                     /gene="mph(C)"
                     /gene_name="Mph(C) family macrolide 2'-phosphotransferase"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             2469..3934
                     /name="msrA"
                     /gene="msrA"
                     /gene_name="msr-type ABC-F protein"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; streptogramin
                     antibiotic; streptogramin B antibiotic"
                     /identity="98.36"
                     /coverage="100.0"
     ARG             4034..4932
                     /name="mphC"
                     /gene="mphC"
                     /gene_name="macrolide phosphotransferase (MPH)"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="98.66"
                     /coverage="100.0"
     ARG             complement(15909..16753)
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     ARG             complement(23817..24118)
                     /name="aad(6)"
                     /gene="aad(6)"
                     /gene_name="ANT(6)"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="99.0"
                     /coverage="36.23"
     Typing          9545..9692
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="5.980000000000001e-72"
     Typing          complement(7028..7770)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          8197..9179
                     /name="rep_cluster_2100"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.593"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          9311..9480
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="93.605"
                     /coverage="91.0"
                     /evalue="1.04e-65"
ORIGIN
        1 ttggagttat ttaaattgaa tggtgaatat tgaaccatcg tttaatgtag atgtagcact
       61 tactttatgg cctaagcgct ttgagattgt gctgacaata tataaaccaa taccgcttga
      121 tttctcactt attctaccgt tatagcccga gaaaccttta tcaaagattt tcggtaaatc
      181 actcgcatta atgccgatac cgttatctcg gattgataat ttctttgtat tttcgtcaaa
      241 cgtaatccac acatctttgc cacgtgcata ttttaatgca ttgtttaata tttgctcaat
      301 cataattgat gcccatttgg catctgttaa tataaccgct tcacttttct cataatgcaa
      361 ctttgtttga tgatgaataa actgtatcgc ataacgttta atcagtggtc gaattaattc
      421 atctacactc acttccataa agaccatgta tgtcttttgg ttcatgagtt tcaaatagtt
      481 cagtgcaaga ttcgtgtaat tatcaatttg taagacttca ttacgcacgt tagaaatcac
      541 gtgttcatca ggatcttcaa gcagtaactt tgatgctgta atcggtgtct tgatttgatg
      601 cacccacatt aaaaaatatg actctaactc actttggtag ttaataaagt cattacgaag
      661 tttatggttt tcgattctta aatcttcgtt ctgttcctgt agtgtttatt cttttttaaa
      721 gttcatgtaa tggatacccc agtaaatcat tgaaacaaac aatacaatac ctagaccaat
      781 catatatgct tgcatcggca cattatacat gaataatata aagtagaata aagcacaagt
      841 aaggatgaca atataaattt cacgttggat tgatttcaag aaattcatac gtcacctaca
      901 cgatatccga catttttctt cgtttcgata aaatctgtaa gtcctagttt ttgtagcttt
      961 ttgcgtaaac gtgtaatgtt gacagcaagc gtattgtcat caatgaagtg ttctgattcc
     1021 cagcattttt cgattaacgc attacgactg acgaatttgc ccttgttctg gaataagcta
     1081 tgcatgattt gcaattcagt gtgtgtcagg tctatggttt cttcattaaa tttaagcttt
     1141 gctgcatcaa gtagtaactc gcaatcatct actgttaaat tattaacttg agtggtgaaa
     1201 tcatacgtgc ggcgtaatag tgcttgaatc ttagtaattg taacagtcat attaaatggc
     1261 tggttctgtt gcaaagtaaa aaatatagct aatcactaat atatcatgtc agtgttcgtt
     1321 taacttgcta gcatgatgct aatttcgtgg catggggaaa atccgtagat ctgaagagac
     1381 ctacggttct ttttatatag agcgtaaata cattcaatac cttttaaagt attctttgcc
     1441 gtattgatac tttgatatct tgtctttctt actttaatat gacggtgatc ttgctcaatg
     1501 aggttattca gatatttcga tgtacaatga cagtcaggtt taagtttaaa agctttaatt
     1561 attttagcca ttgctgcctt cgttgaaggt gcctgatctg taactacctt ttgaggctta
     1621 ccaaattgtt taatgagacg tttgataaac gcatatgctg aatgattatc tcgttgctta
     1681 cgcaaccaaa tatctaatgt atgtccctct gtatcaatgg cacgatataa atagctccat
     1741 tttcctttta ttttgatata cgtctcatca atacgccatt tgtaataagc ttttttatgc
     1801 tttttcttcc aaatttgata taaaattggg gcatattctt gaacccaacg gtagatcgtt
     1861 gaatgatgaa cgtttacacc acgttctctt aatatttcag atatatcacg atagctcaat
     1921 gcatatctta gatagtagcc aacggctaca gtgataacat ccttgttaaa ttgtttatat
     1981 ctgaaatagt tcatacagaa gactcctttt tgttaaaatt atattataaa ttcaactttg
     2041 caacagaacc gtattttatg agtacactct aaattaagga gatgtataat caatctaaaa
     2101 ttgtattttt atacttttgt tatataatct ttctacttag agatatattg taaaaaaacc
     2161 aacaaaatgt tatattaaca ttactatttt atcgatgaag gaggattaaa atgacagctt
     2221 ctatgagact caaataaacc tttttgaata caaaactaaa ttaattcaaa aaggcttgtc
     2281 cgcaatacac actcatagga tgacttatgt cattttttat ccttcgatag gaataataaa
     2341 cgctttcaaa tactaaaaca tcataataaa tttttaagtg tttgaaagtg taatgtgaat
     2401 gagacgggag tagcctgtct catttttttg cgtacacgtc ctttaaatat acaaggagtg
     2461 tataaatatg gaacaatata caattaaatt taaccaaatc aatcataaat tgacagattt
     2521 acgatcactt aacatcggtc atctttacgc ttaccaattt gaaaaaatag cacttattgg
     2581 gggtaatggt actggcaaaa ccacattact aaatatgatt gctcaaaaaa caaaaccaga
     2641 atctggaaca gttgaaacgg ttggcgaaat tcaatatttt gaacagctta acatggatgt
     2701 ggaaaatgat tttaacacgt tagacggtag tttaatgagt gaactccata tacctatgca
     2761 tacaaccgac agtatgagtg gtggtgaaaa agcaaaatat aaattagcta atgtcatatc
     2821 aaattatagt ccgatattac ttttagatga acctacaaat cacttggata aaattggtaa
     2881 agattatctg aaaaatattt taaaatatta ctatggtact ttaattatag taagtcatga
     2941 tagagcactt atagaccaaa ttgctgacac aatttgggat atacaagaag atggcacaat
     3001 aagagtgttt aaaggtaatt acacacagta tcaaaatcaa tatgaacaag aacagttaga
     3061 acaacaacgt caatatgaac agtatataag tgaaaaacaa agattgtccc aagccagtaa
     3121 agctaaacga aatcaagcgc aacaaatggc acaagcatca tcaaaacaaa aaaacaaaag
     3181 tatagcacca gatcgtttaa gtgcatcaaa acaaaaaggc acggttgaga aggctgctca
     3241 aaaacaagct aagcatattg aaaaaagaat ggaacatttg gaagaagttg aaaaaccaca
     3301 aagttatcat gaattcaatt tcccacaaaa taaaatttat gatatccata ataattatcc
     3361 aatcattgca caaaatctaa cattggttaa aggaagtcaa aaactgctaa cacaagtacg
     3421 attccaaata ccatatggca aaaatatagc gctcgtaggt gcaaatggtg taggtaagac
     3481 aactttactt gaagctattt accaccaaat agagggaatt gattgttctc ctaaagtgca
     3541 aatggcatac tatcgtcaac ttgcttatga agacatgcgt gacgtttcat tattgcaata
     3601 tttaatggat gaaacggatt catcagaatc attcagtaga gctattttaa ataacttggg
     3661 tttaaatgaa gcacttgatc gttcttgtaa tgttttgagt ggtggggaaa gaacgaaatt
     3721 atcgttagca gtattatttt caacgaaagc gaatatgtta attttggatg aaccaactaa
     3781 ttttttagat attaaaacat tagaagcatt agaaatgttt atgaataaat atcctggaat
     3841 cattttgttt acatcacatg atacaaggtt tgttaaacat gtatcagata aaaaatggga
     3901 attaacagga caatctcttc atgatataac ttaaaaacta tacactaatt tatattgaat
     3961 attaggttca tttatatcaa tataaaaaat acgttcacaa gaaaaatata atagaaataa
     4021 ggatccaata aaatgactcg acataatgaa attattaaat gtgcagaaaa atatcaatta
     4081 cacatccaac ctcaaacaat ctcattgaat gaatcgggac ttgattttca agttgcattt
     4141 ggaaaagata aacatggagt agaatgggtt ttgagactac caagaagacc tgacgtttat
     4201 aaacgaacaa aacccgaaaa acaaacggta gacttcttac agaagaatgt ttcatttgaa
     4261 ataccgaagt ggaaagtaca tgcaaaagac cttattgctt acccaaaact tacaggtaaa
     4321 cccgcagcca caatagatcc agaaatacaa aattatgtat gggaaattga acacaaacca
     4381 ttaccagaaa actttattaa cacattagct gaaacactcg tagatttaca caacatacca
     4441 gaagaaaaca ttaacgttca gcatataaat atcaaaacca tacaagaaat aaaaaatgac
     4501 tttcaaagaa gaatgaataa agttaaagaa acttatggcg tatcagatga attatggaac
     4561 agatggaaac aatggttaga aaacgacgaa ctatggcctc gacatgcgac catgatacat
     4621 ggggacttac atccaggaca tataatggta gataaccaag caaacgtcac aggtctcata
     4681 gactggactg aagcaaccca ctccgaccca tcaatggact ttataggaca ccatcgtgta
     4741 ttcgacgacg aaggattaga gcaacttata acagcatacg gtaaagctgg aggtgaaata
     4801 tggccacgaa tgaaagagca tataatagaa ctcaatgcag tattcccaat gtttatcgct
     4861 gagtttgcta tggaatcagg agaatcggcg tatgaaacga tggcattgaa agagttaggt
     4921 atgaaagagt agaacttata ttaaaagagg cccattttaa agacgaaggc aatcctgatg
     4981 aaattttaaa actgcgttta attagtgatg gtctttggtt ttctataatg tattaaatat
     5041 ctggacatgg aacaaatgca acaaatggaa ggaatcgttt tcgaaatttc taactcctta
     5101 aatcaggagg ataaataaac ggtcattttc attgaaagca cttatataaa tttcatcaat
     5161 tttaatacct accgtaaata catttcataa gtattaaaca gatgattaaa atttttagtt
     5221 aatttaaata tttatgatag agatgacctt caaatgaacg gttctgttac aaagaaaaaa
     5281 tctatattta tttttagtaa gttttaatta tagatatgta cactttgagt acaccctaac
     5341 catacaaaaa gaattgttga aattataaca attaaaacgt atgattaggg tgtatattta
     5401 ttatggagtg aagatgaatg attataggtt atgcgagagt atcatcgata gatcaaaatt
     5461 tagaaagaca attggataat ttaaagacgt ttggtgtgga gaaaatcttt acagagaaac
     5521 agtcgggaaa gtcagtggaa aatagacctg tatttcaaga agcactcaat tttgtcagaa
     5581 tgggagatcg attcgttgtg gaatctattg atcgtttagg acgtaactat gatgaaatta
     5641 ttgaaactgt gaattattta aaagaaaaag acgttcagtt aatgattacc agcttaccta
     5701 tgatgaatga agtaattggc aatccattac tggataagtt tatgaaagat ttaatcattc
     5761 aaatattagc aatggtttca gaacaagaga gaaatgaaag taaacgtcga caagcgcaag
     5821 ggattcaagt tgcgaaggaa aaaggcgtat ataaagggcg ccctttactt tattcaccaa
     5881 atgctaaaga cccacagaaa cgtgttattt atcatcgcgt ggtggaaatg ttagaagaag
     5941 gcaaagcgat tagtaagatt gcgaaagaag ttaatatcac aagacaaaca gtttatagaa
     6001 ttaaacatga taagggatta tcttgataaa ttgattgtca atgcaaatga gcgtctctca
     6061 cagtgtctca aattccataa catattattg aattgagatt ttaataatta tacaagaaaa
     6121 aagagtacga gttcgcagct ttctatatag taattgtttt actaataagg tgttttaaaa
     6181 tatattataa tgtaaaaagt atttgacatt tgtatcaaaa atatttacac tcataaatgt
     6241 caaatacttt ttacatttat gaggtgttat aatgaattta attcctttta ttattatttt
     6301 aattttttct tgtttatgga cggctataac taacaaatat ttaccttcag aaacattaga
     6361 taaaaaagga caacaagatc gatacgatga aagacaacgt aaaatgttta ttgaaatact
     6421 ggctaaaagt tttatttgga ttgtatattg tatgttattt acactagtgc ttaaatttac
     6481 aggtttgtca ccaagtattg aaggatcttg gttttctcaa tatccagaaa ttttctttat
     6541 aattgtagca ctatttctta tgctgtttaa ttactatact acaaataaaa aatatacatc
     6601 taaaggttaa attaatgaaa aatagaatta gagaatatag aaaacaaaaa ggaatttctc
     6661 aagaaacttt aagtaaagaa ttaaaagtgt ctaggcaaac tattaatgca atagaaaaca
     6721 ataaatatga tcctacattg acattagcat ttaagttggc aagattgttt gatacaactg
     6781 tggatgaatt attttcttaa ccattcattt atcacaaaaa gagagtgcga attcgcactc
     6841 tctttttgtg tagtagtact attaaatttt gtctcaataa cgaacgttta taacgcaatc
     6901 atgatgagag tattaataca gttaattatt tgaaatactt tagtttacat aatcgatgat
     6961 taccagaagt tctcactata taaaagacac taaaatttta taacttttag tgcctaatca
     7021 attattttag ctaccaaaca aacgactcca aaaccccttt ttaggttccg tttcttcact
     7081 cttttcttct atatcactat cattgtcatt tagattagct ggaacgtctt ctttttttgc
     7141 ttcttcacct tgtgtacttt cgtcgctttg acttccagat atatccttat attgaatctc
     7201 tgtttcttta gtttcttcct gatctctgtt aatatttaca ggattagtag tatatgtttt
     7261 ttcttgtgca tcaacgtttt gtctagtgtt agtagatgta tcaaagggat aattaaggtg
     7321 tttttctttt tctaattgat tttctaattt ttgaatcttt ttattactct ctaatgccag
     7381 aacttgctga ttttcaagca attttgatct ttcttgcaac tcttttctgt aaaattcaat
     7441 tgttgtttca tgacgacttt cttgtttttc aatttgatta tttaaagtat caatctgatt
     7501 tttaaggatt tctactattt gagcatcgct tttcgattca aaattaatat tatccgaccc
     7561 ttttttttgt ttgtcttcag tagtactttc aaaaccatat ttctttttat tttcatttac
     7621 tctttgaatg attttttcta tatcggtatc ttctttaata aacgaagtgt tttcctgttt
     7681 tattgtctct atattcaatc gcttaatatt attaaaaatc gtttgcttac taacccctaa
     7741 ttcttcactc aactttttca cacttttcat atcatcaacc ctttataaaa tgtttataaa
     7801 cccttgataa aatattataa gcttataatg cttaataata aagtgattaa taaataaaaa
     7861 taaacatcca tcaacctttt tatcaagggt ttatgaaagg tttatgatat ttatcaaggg
     7921 tttataaacc cttgataaag ctatattttc ccttttataa gtttatttaa agtgctataa
     7981 taaacttaat ataacaaaaa ccccaactac tggtaatagt cggggtttgg taataaaacg
     8041 tttagaaact gtttatttat ataattttcg atacttgtat tatataatga ataatatctt
     8101 agtgcaagca cctaaatcat taaataaatg taaagctaaa taaaaacgtt ttattacctc
     8161 ttaccaaact aaaatatgga aagaggtttt ttgtcatgca aaatcaatat tttacagtgc
     8221 aagaaaatta caaagaaaga ttttatcaaa tccctaaagt attctttacc agtgaaaatt
     8281 ataaaaatct aactaatgat atgaaaatag cctatgctat cttacgtgat cgcttaaatt
     8341 tatctattaa aaatagctgg gttgatgaag atggtaacat ttactttgtt tattcaaatg
     8401 aaaagctaat ggaaatctta aattgtaaaa aagaaaagtt aacaaaaata aaaaaagggt
     8461 tagaaaacga tggtctactc attcaaaaac gacgtggttt aaataaacca aatattctat
     8521 atttaatgaa acctattgtc acagaacgtg atatttacaa aatagaaaaa gaagaaaacg
     8581 atgttgaacc ttacggcgag aaggaagttc gaaaatcgaa cgtccagaag ttcgaaaatc
     8641 gaacgtccag aagttcgaaa atcgaacgtc cagaagttcg aaaatcgaac actaatgata
     8701 ctgactttaa tgacattgac tttaatgata ctgagaataa tgatatgaat gacttgaatg
     8761 atataaagta caaaaatgaa attagtaatc attcaaatca ttcaaatcaa tttacacata
     8821 attttgatga taaagaaatg ctattgcaag aattcccaga acaactaact aattatttat
     8881 taaaatatga ttatagagat ttagaaatca taaaggctgt tattcttaaa gcaaaaaaat
     8941 catttaattc aaggcatgaa gatatgcatt acatgttaga ggacattgag gatgaaatat
     9001 taacttcttt aaaaagactt aaaaaagcta tacatgatag gggagttaaa ggccaaaagg
     9061 aaacaatcaa gtcaatgcaa gcttatttaa tgcaaacaat tctaactgaa cttgaagaaa
     9121 cacatgccct ttatatgcgc cgtaaaaaca tgaaacaata taatatcttt aatcaataat
     9181 tcaaatgatt ttataacact cgaagagaca tcaaaatatt ccgttaaatc atctgacttt
     9241 ttaactgatg acgacgaaaa aaatcaagaa attgtaagtg atttagaaaa aggtttgtat
     9301 cgaaaacgta tgttaagtta tggtggattg cttaaacaaa agcataaaat tttaaactta
     9361 gacgatgccg aagatggtaa tttgattaat acaagtgatg aagataaaac gacagacgaa
     9421 gaaaaaaagc acattcaatt accgcaattt ggaatttcga aaagcaaaat tattatttaa
     9481 gacattagtg ataactgatg tcttttttta ttgtttttct gtaaaaaagt gctgtcttat
     9541 ttttgtgaca aatgctgtat gtagtgtcac aaaagtgtga cactacagct ttgtatgata
     9601 tcactttaaa ataacttaaa acccttggaa tgtctggcct tgccagatct atcatttttg
     9661 aatgatagca aatttccctt atgctcttac ggagatttta gagttaaatt aaaatttcta
     9721 agtttttgat aagaaaagcc ctgcaggaat ttagaaaaac atggggaagt tttaaagtat
     9781 tttatgctaa tttttaaatt tgcatgtaaa tgggcagtat ctaaaaaatt agtcactgat
     9841 tttgctgaaa tttttgtttg tgaaattagc atatatttat ttggctcata tttgcgtttt
     9901 aagagactgt atagattttt aagtacaaaa cctatatgat ttgcctctaa gtcttcaaaa
     9961 tgcctcttaa aatccaaaat aaaagtgttt aatattgtaa taaggattgc tatttttata
    10021 aaaggagaga tatcatgaag attaaaactt tcgctacttt tactcatcgt caattagata
    10081 aacaagttaa taggttttta aagaatgata ttcatgtatt agaaattcaa acacacagta
    10141 attggttata tatttcagct attgtttttt atgaggataa ataaggaaca tcgtatttat
    10201 gccgaaaaaa tttattgatg ttgagaagaa cccttaacta aacttgcaga cgaatgtcgg
    10261 catagcgtga gctattaagc cgaccattcg acaagttttg ggattgttaa gggttccgag
    10321 gctcaacgtc aataaaacaa ttggaataaa atcaacctac agagcatcca gctgcaaatg
    10381 cagttccgca aactgcttca catacaccgc cggctattgg atttacgatt gcccatactc
    10441 cacagtagtg agcacatgca taaagtccag ccatactaca agcgaatgct ttgccgttcc
    10501 atttgaatcc tgcatatgtt accggtctgt ttttatcaac tttttcagcc ttatattcaa
    10561 cgtaattttt gttaataagt atttttccct ctttgttttc agtcatactt cttttttcgg
    10621 caatgaattt tgtgattttt ttgttgtagt tatcatatat tgtttcagaa actacaattt
    10681 cttttgtttt ttcattttta taagcgttat tagctatgta gccatatgca tttttatcat
    10741 ttgcttctgt agctagatat tttaatttag aatttttgtc ttctagcttt atttttttaa
    10801 atccttcttt tttcatttgc ttttcgaatt tttgcatatc ttcattttta ttttgcaatt
    10861 gttctagaaa acttatttct ttcttggtca tttgtgatac ttcgatgttt ttgcttttca
    10921 atttttcttt ttgattttct agtaaagaac ttttttgttc ttcatttgcg taagcattag
    10981 aaaaattcgc gctaaatacc agtaggaaca aggaaattat tgaaaataat tttataattt
    11041 tcatttgata cctccaagat aataagatat tttaattgta taagtaagcg ctttataaaa
    11101 tcaatattta ttttaatata tttataaaca tatttttgaa aggagtctat tttatgaatg
    11161 aaaatttaga aaaatatata aaaagtttgc cacttttagg tttgttaatt agtattttgt
    11221 taattgtttt attctttttt attttagatg ttgatgaaga tttattcgtg gtttttttat
    11281 actgtttatt gcctttgata gttaatttgt ctatttatgg tttttatgtt tttgttaaaa
    11341 gaaagtaaga ttatgaataa ttttgttttt aatttgtatg ctttgagggg gttggaaaac
    11401 ggtaggtgta tagattagat ttcttgtttt tttgaaacga gtgtgaacga gtttcttctt
    11461 gtcttgattt ttgataaaaa cgccctacag gaatttagaa aaacgtgggg aagttttaaa
    11521 gaattttatg ctaattttta atttgcatgt aaatgggcag tgtctaaaaa tagttattgt
    11581 ttttgctcaa atttttgttt ttgaaaatag catatattta tttggctcat atttgcgttt
    11641 taaaagcata tataagtttt agatataaaa ctatatgaat cacccctaaa tctttaaaat
    11701 gccctcttaa aattcaaaat aagggcataa aaaataaaag ctaccccaga taaagtgagg
    11761 tagctttttc tttcatacgg tctatttatt tttctttcga cgccgtatcg tcgatgtaat
    11821 tcaaaaaagt tatgggctat aaatctacat cactttttca agaatgtagt agcaatattc
    11881 aacgcaaatt aatttttata actgctcgga atatctcaag ccgtttcttt aattttgaaa
    11941 taaaaaaatc gacgaaggtc gattacgttt ttgcacatgt cgatttatcc gacgtataag
    12001 tgcgccctta cgggatttaa ctagattata acgacgaatt ttagacctgt aaagcaataa
    12061 caattaggtc taccaggtag ataaagtgta caaagtagaa ccgaaaaagt tatttatttt
    12121 gaagattttt cgtagatata atttgctaat aaacttccta aaactgaata aagaaaaata
    12181 gttaaactca tgtaatcact ccataattct gaagtgtctc catgtctacg catagacacg
    12241 catttatgcc gaaaaaattt attgatgttg agaagaaccc ttaactaaac ttgcagacga
    12301 atgtcggcat agcgtgagct attaagccga ccattcgaca agttttggga ttgttaaggg
    12361 ttccgaggct caacgtcaat aaagcaattg gaataaagca cctatgatta tttaaaaata
    12421 taagttataa tacattcaaa aatatttttg aatgaggtgt attatgattc aaacggttgt
    12481 tgctgctgct gttctttata ttgctacagc agttgattta ttagtaattt tattaatatt
    12541 ttttgctaga gcaaagacta gaaaagaata tagagatatt tatgttggtc aatatttagg
    12601 gtctattatt ttaatattag ttagtttgtt tttagctttt gtattaaatt atgttccaga
    12661 aaagtggata ttaggtttat tgggtttaat accaatttat cttggaatta aagtggctat
    12721 ttatgatgat tgtgaaggag aaaagagagc taaaaaagaa ttgaatgaaa aaggattgtc
    12781 taaattagtt ggtacggttg caattgttac gatagcaagt tgtggcgccg ataatattgg
    12841 tttatttgtt ccgtattttg tgacattaag tgttactaat ttattactta ctctgtttgt
    12901 ctttttaatt ttaattttct tcttggtgtt tactgcacaa aaattagcta atattccagg
    12961 aattggagaa attgttgaga aatttagtcg ttggattatg gctattattt atatagcttt
    13021 aggtttattt attattattg aaaatgacac tattcaaaca attttaggat ttatatttta
    13081 atttagggtg tgattttata tgagttatga aaatacttgt gatgtgatct gtgtacatga
    13141 ggataaagtt aacaatgctt taagtttttt agaagatgat aaatctaaga aattacttaa
    13201 cattttagaa aaaatttgtg atgagaagaa attgaaaatc atattatctt tgattaaaga
    13261 agatgagttg tgtgtttgtg atatttcttt gatattgaaa atgagtgttg cttcaacttc
    13321 acatcattta aggcttttat ataaaaatga ggtacttgat ttttataaag atggaaagat
    13381 ggcatattat tttattaaag acgatgaaat aagagagttt ttctctaaaa atcatgaggg
    13441 tttttgaaac gagtttcttc ttgtcttgat actataaaaa acaaagttat ataacataag
    13501 acgacttatc ggaagtagat atgcttgtat attcacagat ggtataataa tagagtcgcc
    13561 tatctctcag gcgtcaattg acgaagagag gaggtgcatt actttgctaa tcattttcgt
    13621 tcacatcata gcaccagtca tcagtggctg tgctgttgcg tattatactt attggcttag
    13681 taaacgcaac aaataattaa taggcgactt tataagccag catcgaaaaa atccccacac
    13741 tactgcaata gtgtggggat tggtgcatta attgttaatc attttcgtta tataaattat
    13801 aacactggtt agtagagaaa tgcaaaatga ttgaattaat agtaaatgta ttaatgaata
    13861 ctcacactta tacttttaaa atagttcttc ctaaatgttg tccttttaaa agctgatcta
    13921 tcgttttata gaattcttca aatccaattt cattgtatag aagtgaattt cctatattcc
    13981 attcatttgc taacttactc catatatctt cacggatatt atgatcaaca tatacagaat
    14041 caatgccaat taatttaata cctctaagaa taaacggtaa tatattagcg ttaagtgaat
    14101 ttcctgctac atttccacat acagtagcaa caccttgata atttagacgt tttaaaccgt
    14161 ataatgttac attactcccc actgtatcta agaaataatc aaaaatacct tttttaagcg
    14221 gtttattatc atcttcaatt attattactt gttttgcacc taattttttt gcgatttcta
    14281 tttgcttttc ttttcttacg atagcagtga tattttcata tccaatttta tgtaaaattt
    14341 gtatagcaac actgcccaca ccacctgtag ccccagacac taaaatttca ggttgtgatt
    14401 tgatattcat tccatatttt tctagttcaa aaattgataa tgctgccgta aaaccggctg
    14461 tgccatatac catagactct ttaatagaca tttcttgggg aataggaaca atccactctc
    14521 caggcacttg tgcatattct gaaaatccac ctgtatgtgt cacgccaaca tcataaccag
    14581 taactaatac attatcgcct tctttaaact tatcattcga acttgattca acaatacctg
    14641 caaaatctat accaggaatc ataggataat ctctaattac accgccttta tattgtaaag
    14701 ctagcatatc cttataattt attgaagagt ataccacttt tactaataca tcacccttcg
    14761 ataaatgaga ttcatcaact ttttctactt tataactaac atttgatgca ctttttctca
    14821 ctactaccgc attgaacatt tattagcctt ctttcacaat tgttttgtag aagtatgttt
    14881 ttgttgcaaa actattttcc tacaaaactt atcatgatat gataagcgag tcaatactaa
    14941 tgatttaaga gaggttttag ttgtggaatt agataattgt ataaattatt tgttgagtac
    15001 ttctcagaat agagttttta aacattttaa aagtttatta agtccctata atattactcc
    15061 agcagaatat ggtgttttga attgcttgat taatagtaat ttgaatacac ctaaagcgat
    15121 tggtaatact ttaaatttag aaccttcaac aatatctgga atattagata agatgtccaa
    15181 aaaggatcta ataacacgtc aaactgataa tgaaaataga agaactgtgc taataaacag
    15241 tacaaataaa gcaaaagact tatggccaac attagaaaag aaagcctatc aacttaataa
    15301 tcattacttc gctaatttaa ctaatgaaga aactgtagtg tttaaaaaga tattactaaa
    15361 gataaataaa actacgtttt aatttttacg ttataaaaaa gttgaagtgc gaattataat
    15421 cgagtaaata taaatgatag cttagcttaa ttatatatta aagccaacta tacttttatt
    15481 cccgaaaaac ctactatcca aatttctaag atactttagc ctctataata aacatattgt
    15541 aatataattt atgtattatt taggtttacc ctaatcgaac aataaaaaat acttgtaaaa
    15601 tgctattgtc actttgcttg atatatgaga attatttaac cttataaatg agaaaaaagc
    15661 aacgcacttt aaataagata cgttgctttt tcgattgatg aacacctata attaaactat
    15721 tcatctatta tttatgattt tttgtatata caatatttct agtttgttaa agagaattaa
    15781 gaaaataaat ctcgaaaata ataaagggaa aatcagtttt tgatatcaaa attatacatg
    15841 tcaacgataa tacaaaatat aatacaaact ataagatgtt atcagtattt attatgcatt
    15901 tagaatatta aaattccttc attacactct tggcggtttc acttatcaac ttatcatttg
    15961 gcttatcact tttattgtct ttattcgtaa aaatgactaa aacaataggt tcagattggc
    16021 ccttaggata aacaaaagca acatcatttc tagaagcata tgttattgct tgaccacttt
    16081 tatcagcaac cttatagtct tttggaacac catctttaat taaagtgtct ccgtttttat
    16141 tattaaacat taaatcaagt aagaaatttt tatttttttt gcttaatttt ccatttgcga
    16201 taagtttatt taaagtcttg ccgaaagcag caggcgttga agtatctttt ttgctctttg
    16261 gtgaatagta atttaattct atctcatatc taactggatt tgttacttta tctcctagtt
    16321 cttttagacg ttgtttaact tttttgattc caccgatttc ttttataatt ttattgtttg
    16381 ctgtattatc actatatgtc attgaagcct caataagttc ttttaaagtg atatcttttc
    16441 ctacatattt ttctaaaata ggagaataag caactatatc atctttgtta atatgtactt
    16501 ttttatttaa cttattataa ggtacttgtt ctaacaaaat agcactattt atcgcttttg
    16561 aagtcgaagc ataggcaaat ctcttatctg aattaaattt tacttcctta ccacttttag
    16621 tatttaaagc ataaacacca atatgagcat tatatttttt ttctaaatca tttaactctt
    16681 tggcatgtga actgtttgaa ttacatgcac ttaaaactaa agcaattaca attaaaaata
    16741 ttaacttttt caaaataaac cctccgatat tacagttgta atttttataa atcaataata
    16801 ttacaattgt aatattgatg tcaattgttt attataaata tttgaaagaa ggtgtcaaaa
    16861 tggctaaatt actaataatg agcgtagtaa gcttttgttt tatatttcta ttgttagtat
    16921 tttttaggta catattaaaa cgctatttta attatagttt aaattataaa gtttggtatc
    16981 taactatgct tgctggatta attcctttta tcccaattaa attctctttt ataaaattta
    17041 ataatgtgaa taatcaagcg cccacagttg aaagtaagtc acacgatttg aaccataaca
    17101 taaataccac caaacctatt caagagttca caacagatat ccataagttt aattgggatt
    17161 caattgataa tatctgcaca gttatttgga tagttttagt tattatttta agttttaaat
    17221 ttttgaaagc cttattatat cttaaatatt taaagaaaca gtcactttat ctaaacgaaa
    17281 atgaaaaaaa taaaatagat acgatacttt tcaaccatca atataaaaaa aatattgtga
    17341 ttcgaaaagc agaggctatt caatctccaa taactttttg gtatgggaaa tatattattt
    17401 tgattcctag ttcatatttt aaaagtgtaa ttgataaaag actaaaatat ataatactgc
    17461 atgaatatgc tcatgctaaa aatagagata ctttacattt aattatcttt aatatcttct
    17521 ctattattat gagttacaat ccattagtac atattgtaaa aagaaagata attcatgaca
    17581 atgaagtaga agccgataga tttgtcctta ataatattaa caaaaatgaa tttaaaactt
    17641 atgcggaatc tattatggac tccgtattaa aaaccccatt ttccaacaaa aatatattaa
    17701 gccattcatt taatggtaaa aaatcattac tcaaaagtag attaattaat ataaaagaag
    17761 ccgatctgaa aaagcagtca aaattaattc taatttttat ttgtattttt acttttttta
    17821 tcatgataat tcaaagccag tttttaatgg ggcaatcctt aactgattat aattataaaa
    17881 agcccttaca aagcgattac caaattttag atgaaagtaa aaattttggt tcaaatagtg
    17941 gatctttcgt tatgtacagc atgaagaaag acaaatacta tatttataat gaaaaagaaa
    18001 gtagaaaaag atattctcct gattcaactt acaaaattta tttagcactg tttggacttg
    18061 accgtcatat tataagtgat aaaaattcac gtatgtcatg gaatcataaa cattatcttt
    18121 tcgagtcttg gaataaggaa caagatttaa atacagcaat gcaaaattca gttaattggt
    18181 acttcgaacg tattagtaat caaataccaa agaactatac tgcggctcaa ctcaagcaat
    18241 taaattatgg taatgaaaat ttgggaagtt ataaaagcta ttggatggaa gatagtttga
    18301 aaatatctaa tcttgaacaa gtaatagttt ttaaaaatat gatggaacaa aataaccatt
    18361 ttagtaaaaa agcaaagaat caattatctt cttcattatt gattaagaaa aatgaaaagt
    18421 atgaactgta tgggaaaaca ggtacaggta tagtaaacgg gaagtataat aatgggtggt
    18481 ttgtaggtta cgtaattaca aatcatgata agtattattt tgctacacat ttatcagatg
    18541 gaaacccgtc tgggaaaaat gctgaattaa taagtgaaaa aatattaaaa ggaatgggtg
    18601 ttttaaatga ccaataagca agttgaaata tctatggctg aatgggatgt tatgaatata
    18661 atatgggata aaaaatcagt atcagctaat gaaattgtag ttgaaattca aaaatataaa
    18721 gaagttagtg ataaaacgat tagaacatta atcacaagac tatataaaaa agagattata
    18781 aaacgataca aatcagaaaa tatttatttt tactcatcaa atattaaaga agacgatatt
    18841 aaaatgaaaa ctgctaaaac ctttcttaat aaactgtatg gaggggatat gaaaagttta
    18901 gtgctgaatt ttgcgaaaaa tgaagaatta aataacaaag aaattgaaga attgcgagac
    18961 attttaaatg atattagtaa aaagtaatta gaggtatgtt tcaaacataa tacatatgta
    19021 aaccatactt gactcttatt aaattagttt tgttaatgac atttaaaata tattattaaa
    19081 gatgagagtg tccagaaaat aaccattttc tgtacactct tgttttttgt ctaaataagt
    19141 aagtattaca tagaattatg tgttcaaaaa cccaacaaaa aatctatgtt cacaaaagac
    19201 ctcgtaatca agttatggta cactaaaggt gtatatagga ggtctgtatt ttgaaaatag
    19261 gttatgcaag agtttcaact ggattacaaa atttgaattt acaggaggat cgattaaata
    19321 catatggttg tgaaaagata tttaatgacc atatgagtgg ttcaaaaagt aagcgacctg
    19381 gtttagataa agcaattgaa tttgcgaggt caggagatac gattgttgtt tggagattag
    19441 atagactagg acggaacatg gaggatttaa tcacgttagt taatgaactt aacgaacgag
    19501 gtgtgagttt tcatagttta gaagaaaata taacgatgga taaatcaagt tctacaggac
    19561 aattattatt tcatttattc gcagcatttg cagagtttga acgtaattta attttagagc
    19621 gatcatcagc cggtcgaatt gcagcacgtg ctagaggccg atatggaggt agacctgaaa
    19681 aattaaataa acaagattta aacttactta agacacttta tgataatggt acgccaatta
    19741 aaacaattgc agagcagtgg caagtttcac gtacaactat ttatcgttat ctcaataaat
    19801 tagaggcaaa agagaataaa aacaagtaga gcaactaatc tagcttacta taatgaatct
    19861 actaaataat tttatatatc attaacatac aaagactttg attcaatgtc actcgatgta
    19921 aaagagacgt tctgacagcg tctaaaatct cataatattt tcctgttatg agattttaat
    19981 aataacacaa gaaaaaagcg tacaaattcg tacgcttttt taatataata cctgtttcac
    20041 taatgaacgt tttaagtatc ttcatcatta actgaaacta cagtaataat actcgtcaac
    20101 aatattagta tagttaaaat agaaagactt aggactggca taaccgaact aaaattatat
    20161 ttgaaatata aaagtgctaa tgaagagaga aatgtaaaaa taataaatac caaagaccat
    20221 ttttctaatt tattcattgg cttcacctct ttgaactttt atataatcat aggagatatt
    20281 tttactacga tttataaaaa ataagaagat aatcattatt aaagaaacga ttaatataat
    20341 gttgaatcct atagtatcac ctaattcgtt tacacctttg cctaatatcg gagatacaaa
    20401 gctttgtatt aataatgaaa gagatgccca tatagtaaat gaggttctgt tgcaaagttg
    20461 aatttatagt ataattttaa caaaaaggag tcttctgtat gaactatttc agatataaac
    20521 aatttaacaa ggatgttatc actgtagctg ttggctacta tctaagatat gcattgagtt
    20581 atcgtgatat atctgaaata ttaagggaac gtggtgtaaa cgttcatcat tcaacggtct
    20641 accgttgggt tcaagaatat gccccaattt tatatcaaat ttggaagaaa aagcataaaa
    20701 aagcttatta caaatggcgt attgatgaga cgtacatcaa aataaaagga aaatggagct
    20761 atttatatcg tgccattgat gcagagggac atacattaga tatttggttg cgtaagcaac
    20821 gagataatca ttcagcatat gcgtttatca aacgtctcat taaacaattt ggtaaacctc
    20881 aaaaggtaat tacagatcag gcaccttcaa cgaaggtagc aatggttaaa gtaattaaag
    20941 cttttaaact taaacctgac tgccattgta catcgaaata tctgaataac ctcattgagc
    21001 aagatcaccg tcatattaaa gtaagaaaga caaggtatca aagtatcaat acagcaaaga
    21061 atactttaaa aggtattgag tgtatttacg ctctatataa aaagaaccgc aggtctcttc
    21121 agatctacgg attttcgcca tgccacgaaa ttagcatcat gctagcaagt taagcgaaca
    21181 ctgacatgat aaattagtgg ttagctatat ttttttactt tgcaacagaa ccagcatttg
    21241 ttttaatatt tgttccaaag agccatcatg gctttgacag agctcttctt ctatgcaaat
    21301 gcttttaatc cgatccacac gaaaattcct atattcattt cttagcctgc aaaaccgatt
    21361 aagtaccagt tctgttcata aaaccccagt gatataggct ctatcattct gctttccggt
    21421 tcttgccctc ctgatgcagg atattgaatt gatattaccc ttttattgca gattgcagtc
    21481 tgaattgctg caataacgtt atccgccaat gtatttttct gtccagatgt gctgtacacg
    21541 ttaatactgt tctccaactc ctgtgcatag tttttttcac catgcttcaa aatagatttg
    21601 attttataca tagctgaatc aaaatccttt ataaatgatt catctccatg gcaatttaaa
    21661 aatttccctg ctgtaatcaa tgcacccact tccgccgctg taaacattac cggcagaagt
    21721 aggaagccct ctacaagaaa atatcctttt ccggcctcag atccaattgg tattccggct
    21781 tcttcaagtg tccggatatc tctgtaaact gtccttaagc ttatattaaa tcgctgtgca
    21841 atttctttgg caggaattat ttttttgatt gcagctgaat aagaatagag gttactctgt
    21901 taatcctgtt caaattttat tcctcctctg tgacttccat aaaaagtata tcctatgcgt
    21961 tcttaagcta gctgctgtta gtgcttctca ttgcaccctg gttataaaag ccatactcac
    22021 aaacctcttc accaaaactc tttacatctc taatatagaa ctctatctag cgaactttta
    22081 gaaaagatat aaaacatcag agtatggaca gttgcggatg tacttcagaa aagattagat
    22141 gtctaaaaag cttgtagtta aagcttttta gacatctaaa tctaggtact aaaacaattc
    22201 atccagtaaa atataatatt ttattttctc ccaatcaggc ttgatcccca gtaagtcaaa
    22261 aaatagctcg acatactgtt cttccccgat atcctccctg atcgaccgga cgcagaaggc
    22321 aatgtcatac cacttgtccg ccctgccgct tctcccaaga tcaataaagc cacttacttt
    22381 gccatctttc acaaagatgt tgctgtctcc caggtcgccg tgggaaaaga caagttcctc
    22441 ttcgggcttt tccgtcttta aaaaatcata cagctcgcgc ggatctttaa atggagtgtc
    22501 ttcttcccag ttttcgcaat ccacatcggc cagatcgtta ttcagtaagt aatccaattc
    22561 ggctaagcgg ctgtctaagc tattcgtata gggacaatcc gatatgtcga tggagtgaaa
    22621 gagcctgatg cactccgcat acagctcgat aatcttttca gggctttgtt catcttcata
    22681 ctcttccgag caaaggacgc catcggcctc actcatgagc agattgctcc agccatcatg
    22741 ccgttcaaag tgcaggacct ttggaacagg cagctttcct tccagccata gcatcatgtc
    22801 cttttcccgt tccacatcat aggtggtccc tttataccgg ctgtccgtca tttttaaata
    22861 taggttttca ttttctccca ccagcttata taccttagca ggagacattc cttccgtatc
    22921 ttttacgcag cggtattttt cgatcagttt tttcaattcc ggtgatattc tcattttagc
    22981 catttattat ttccttcctc ttttctacag tatttaaaga taccccaaga agctaattat
    23041 aacaagacga actccaattc actgttcctt gcattctaaa accttaaata ccagaaaaca
    23101 gctttttcaa agttggcgta taacatagta tcgacggagc cgattttgaa accacaatta
    23161 tgatagaatt tacaagctat aaggttattg tcctgggttt caagcattag tccatgcaag
    23221 tttttatgct ttgcccattc tatagatata ttgataagcg cgctgcctat gccttgcccc
    23281 ctgaaatcct tacatacggc gatatcttct atataagcgt accggttcca attttttcgc
    23341 agtttaactt ttccgacgca tttatcgtct tggtagcttt ttaaatatgg cgcttcatag
    23401 agtaattctg taaaggtcca attctcgttt tcatacctcg gtataatctt acctatcacc
    23461 tcaaatggtt cgctgggttt atcgatatct ttcaggtgcc ctgctttcat ttctgtaatc
    23521 actgttcccg cctctcttct atatcagcgg catatgtgct atccaggcag ccggttttac
    23581 cagtgtattt tttatacatg tccctggtat attttgttat attcctatca tactccggat
    23641 aggcataatg aagcctttcc gccacctcac cggataccgc cctgaacaat tgatggcata
    23701 gaaataatgc ttcccatatg ttttcatagg aatccatccg gtaggtggac aaaagtttct
    23761 cccacaaatc ctcggatata tacctttcaa taaacttata gttcttgcct acacttcatt
    23821 taaagcctgt ttcgatgccg accttccatg atatcattct cagcagctca tggcgaacaa
    23881 tctgattaaa atgatcaata gcaaataaaa tttccttacg gcacaatcct ttaataacat
    23941 aaggtgttac attccaaaat tcattgcagc aatcatcata ctcccttgcg cttggctttc
    24001 ttacatgata atctatatca gtcggaacta tgtccctttt aattctacaa tctttatcaa
    24061 ttagaacctt tattaattta tcgcccttta ggtaattatc taactcttcc aagggcaata
    24121 aggtaagatc aattttattg taatcatcaa atagctataa tagatttaga ggtaaagaaa
    24181 ttaaatacat tgaagagcag aaagatttta caaaagagta ttttaataaa aatgatggtt
    24241 ctgttgcaaa gtaaaaaata tagctaatca ctaatatatc atgtcagtgt tcgtttaact
    24301 tgctagcatg atgctaattt cgtggcatgg cgaaaatccg tagatctgaa gagacctgcg
    24361 gttcttttta tatagagcgt aaatacactc aatacctttt aaagtattct ttgctgtatt
    24421 gatactttga taccttgtct ttcttacttt aatatgacgg tgatcttgct caatgaggtt
    24481 attcagatat ttcgatgtac aatggcagtc aggtttaagt ttaaaagctt taattacttt
    24541 aaccattgct accttcgttg aaggtgcctg atctgtaatt accttttgag gtttaccaaa
    24601 ttgtttaatg agacgtttga taaacgcata tgctgaatga ttatctcgtt gcttacgcaa
    24661 ccaaatatct aatgtatgtc cctctgtatc aatggcacga tataaatagc tccattttcc
    24721 ttttattttg atatacgtct catcaatacg ccatttgtaa taagcttttt tatgcttttt
    24781 cttccaaatt tgatataaaa ttggggcata ttcttgaacc caacggtaga tcgttgaatg
    24841 atgaacgttt acaccacgtt ctcttaatat ttcagatata tcacgatagc tcaatgcata
    24901 tcttagatag tagccaacgg ctacagtgat aacatccttg ttaaattgtt tatatctgaa
    24961 atagttcata cagaagactc ctttttgtta aaattatatt ataaattcaa ctttgcaaca
    25021 gaacctccta actgtattac caccttaaaa gtagttgcag acgcacttcc taaatcgtca
    25081 gcagtgttta accacatatc atcaacaata atcatatgac ctgttgatga tactggagca
    25141 aattctgtca acccttcaac tacacctaaa ataaatgctt taatctgctc tataaaaccc
    25201 atttttctcc tccttttaac ttatatcagt ttttttaaag tatgagaata atataattac
    25261 actgaatata gatgtaacaa ttatgataat taaagataat agaaatggat aagtattagg
    25321 taatgttcct ctagatatgt ctccaactgc agcccaagga aataatcctc tatgttcaga
    25381 attagcagtc attaaattta tcaaagtaat tattatggtt aaaacaattg tgggaacata
    25441 atttttaaaa tatatcgaca aaataattat tggtggagat aatatccata ataacactcc
    25501 gccaataaca aatgtaaaga atgaatcaat tattaaactc tggcttaacc cttgaaaatg
    25561 caatagcata cctagcatta aagttagcaa ccatgcaata acagatagtg tttgaatcca
    25621 caagaataat aatattattt tacttactaa aaaactttct ctagatatag gtataattaa
    25681 taagtttttt aaagtatctt ctatatattc tcttccaaac aaataggcta ttataacccc
    25741 atatagagga ggtccaataa ttagcatatg atataaactg acttcttcaa ataactgttt
    25801 aaatacaata ttaggagtcg gtactttcgt ccgcatacta ataaaagaag ctacaaccac
    25861 cataaaaggt gctacgcatg tacctaaaat acttattaga aacatatatg atctttttaa
    25921 cttaataaat tctgtacgga gtagattatc caattgtgcc acctcctact aagtcttcga
    25981 aataagtttc tagattatct tctatcactc tcatctggaa aacatcaata ttgtttaata
    26041 ctaataatct attaatttct tgttgtctat caatatgtga ataaatttta aattcgccat
    26101 tttctttaat tttatagtca taaattccga agttagtttc caacaaacat gcaacttttt
    26161 cttcatctga tactgatata cttataaatt gtctgttctt tttttttaaa tcttcataca
    26221 taatttcttc taacaaaact ccgttatgaa taatacccac cttgtctact aactgctcta
    26281 tttctgacaa tatatgactt gaaattaaaa tggttatatt tctagattga gccagatcct
    26341 taatcaactt tctaatttct tttatgccaa taggatctaa tccattcgtc ggctcatcaa
    26401 gtatcaataa ttcgggattg tgcaataaag ctctcgcaat ccctaaacgt tgcttcatac
    26461 ctaaagaata atttttaaac aattttactt tttcagaagc tagtcctact atttctaaca
    26521 cttcttcaat tgcattttct ttttgtatac ctaatatttt agcatttata gttaagttct
    26581 ctttagctgt caaattacta taaaaacctg gcgtttcaac catagcacca atatttttta
    26641 aaatttcagt tttattactt tcgaactctt tttcaaatat tttaatatta cctttcgtag
    26701 gtttaattaa gcctaaaagc attcttatag tagttgtttt gcctgcacca tttcttccta
    26761 aaaaaccata aatttgtcca ctttcaacag ttatactcaa attattaact gctatctgac
    26821 ttccatattg ctttgttaag ttatttattt caattatatt attcaaattt ttcacctctg
    26881 gcacctttct tagtttgttg ttacctttat cttacgcgcg attagaaaag gctgccttta
    26941 tctattctta caaaaacagc cgctaatctt acaaaaatga aaga
//
