LOCUS       NZ_CP029585             8809 bp    DNA     circular CON 26-NOV-2023
DEFINITION  Klebsiella pneumoniae strain DA33140 plasmid pDA33140-9, complete
            sequence.
ACCESSION   NZ_CP029585
VERSION     NZ_CP029585.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN09245749
            Assembly: GCF_003181055.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 8809)
  AUTHORS   Nicoloff,H., Hjort,K. and Andersson,D.I.
  TITLE     High prevalence of unstable heteroresistance caused by gene
            amplification in clinical bacterial isolates
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8809)
  AUTHORS   Nicoloff,H., Hjort,K. and Andersson,D.I.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-MAY-2018) Department of Medical Biochemistry and
            Microbiology, Uppsala University, Husargatan 3, Uppsala 75442,
            Sweden
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: CLC Genomics workbench v. 11.0.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 20.0x
            Sequencing Technology             :: PacBio; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/26/2023 01:17:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,534
            CDSs (total)                      :: 5,410
            Genes (coding)                    :: 5,298
            CDSs (with protein)               :: 5,298
            Genes (RNA)                       :: 124
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 88
            ncRNAs                            :: 11
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 49 of 112
            Pseudo Genes (incomplete)         :: 64 of 112
            Pseudo Genes (internal stop)      :: 19 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP029585.1.
            Bacteria and source DNA available from Dan I Andersson.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..8809
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="DA33140"
                     /serotype="ST147"
                     /host="Homo sapiens"
                     /db_xref="taxon:573"
                     /plasmid="pDA33140-9"
                     /geo_loc_name="Sweden"
     gene            complement(join(7915..8809,1..221))
                     /locus_tag="DLJ83_RS27730"
                     /old_locus_tag="DLJ83_27730"
     CDS             complement(join(7915..8809,1..221))
                     /locus_tag="DLJ83_RS27730"
                     /old_locus_tag="DLJ83_27730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019405083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="WP_012579087.1"
                     /translation="MIKEISLKNFKCFNELYLKQLKTLNIIAGKNNYGKTSILDAIFCF
                     YDVKNPAVLLNIQAFRKEMAEINKNKPFWVSYFHDMDTSQKMSIVIRDERSEVTQTYET
                     ETNQRLESSLSLNVDTVLSNQNIPRQTIGSQATVNSLKINVTETPNAKNRVSNKLFSMQ
                     LKEDGVEIKSEIKNERDGINYKFKTATIITTSRKINKEATITNVSSLLTQKRKKDILEN
                     LKKIDDRIVDIAISAIGNNKEIYLDIGFSELNEISMLGEGISRALSFISSVLVQENSII
                     LIDEIENGIHYSVIKDIIKSLISSAKQNNNQIFATTHSQDVIRAINEIDSKNEDIAYIR
                     LGREKNSLKPTAVQFNMDDFSYSVENDWEVR"
                     /name="ATP-binding protein"
     gene            complement(566..679)
                     /locus_tag="DLJ83_RS29670"
                     /old_locus_tag="DLJ83_27735"
                     /pseudo=""
     CDS             complement(566..679)
                     /locus_tag="DLJ83_RS29670"
                     /old_locus_tag="DLJ83_27735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007772075.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /name="replication initiation protein"
     gene            1095..1286
                     /locus_tag="DLJ83_RS27745"
                     /old_locus_tag="DLJ83_27745"
     CDS             1095..1286
                     /locus_tag="DLJ83_RS27745"
                     /old_locus_tag="DLJ83_27745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_004187666.1"
                     /translation="MTKQQKTALNMAKFIQNQSLLLLEKLNELDLDVEADLCEKLHDDA
                     EHLFRTLSSRLDALQDGN"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            1286..1687
                     /locus_tag="DLJ83_RS27750"
                     /old_locus_tag="DLJ83_27750"
     CDS             1286..1687
                     /locus_tag="DLJ83_RS27750"
                     /old_locus_tag="DLJ83_27750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009310048.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_012579088.1"
                     /translation="MARVSISEAARLTGKSRTTLHRLIKAGDLSTCSGERNAKMVDTSE
                     LLRVFGPFEQPKGEHHSGQVSGQRDTASADQSEQVIRHLKQEIEHLNTLLLSKDSHIDS
                     LKQAMLLLENHQAKLTESPAPWWKFWKKS"
                     /name="helix-turn-helix domain-containing protein"
     gene            complement(2530..2739)
                     /locus_tag="DLJ83_RS27760"
                     /old_locus_tag="DLJ83_27760"
     CDS             complement(2530..2739)
                     /locus_tag="DLJ83_RS27760"
                     /old_locus_tag="DLJ83_27760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdgH/BhsA/McbA-like domain containing protein"
                     /protein_id="WP_009310047.1"
                     /translation="MKSIKTFVAVAALSMMSFGAFAQSVSATASTLDRAEAKIAAQAAE
                     QGASYKITSAQFNNRVHMTAELTK"
                     /name="YdgH/BhsA/McbA-like domain containing protein"
     gene            3127..3309
                     /locus_tag="DLJ83_RS27765"
                     /old_locus_tag="DLJ83_27765"
     CDS             3127..3309
                     /locus_tag="DLJ83_RS27765"
                     /old_locus_tag="DLJ83_27765"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_080882243.1"
                     /translation="MGKELSLNKIYDKNSRYINDSRGHELGKEKKVFDFEVEMIKKRRE
                     DAIRKIIEDSKSLKW"
                     /name="hypothetical protein"
     gene            3322..5004
                     /locus_tag="DLJ83_RS27770"
                     /old_locus_tag="DLJ83_27770"
     CDS             3322..5004
                     /locus_tag="DLJ83_RS27770"
                     /old_locus_tag="DLJ83_27770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001697690.1"
                     /GO_function="GO:0019239 - deaminase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-phage dCTP deaminase"
                     /protein_id="WP_227538319.1"
                     /translation="MSLARKLREKRSNPIHSANEDSSGGDSINQITSRQSMDLVIGFCG
                     AVGSGIKSIVDVTEEELDDLGYDVYRIRVSELMQKLFSEWRDDIVTPFDRYHKLQDFGD
                     ALRNKYYPHILSEAVIHEIKIEKGIDTSSKKNKKAFLVDQLKHQDEIELLRMVYQHNFY
                     LLGVIRSEVERKRNLRDEGLSKSEVDIVIHHDRKSESDYGQQTAKAILDSDYFVKNNQG
                     QRAHLKAKVKRFIGLIHGLNGLTPTTYEKGMYAAHSASLQSACLSRQVGAAILDVNGNL
                     ISVGRNDVPKFNGGLYSADDGVNDHRCVYKGGKCYNEVRKLKIKSKISQILMSESACEL
                     GVKLTEDQAEQLADVIYKKTPVSSIIEYSRSIHAEMDAITSLARLGNGGFSDKVLYTTT
                     FPCHNCARHIVAVGITKVVYIEPYEKSLALELHDDAITEVNEHGKVIFESFEGVSPRRY
                     QKFFFSTDERKDSFGNAEKYSTKYKNHIDIQFIDSYLDFENRVVDIFRTNTNIDSGNHV
                     GRTDSTINLSSQPVPPVPPVPPVPSVPPVPPVPPVPPVPPDSK"
                     /name="anti-phage dCTP deaminase"
     gene            complement(5208..5321)
                     /locus_tag="DLJ83_RS30055"
                     /old_locus_tag="DLJ83_27780"
     CDS             complement(5208..5321)
                     /locus_tag="DLJ83_RS30055"
                     /old_locus_tag="DLJ83_27780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_080882241.1"
                     /translation="MHEPPVQSDCCVLSGNYHLESNPVRHAKAPLAAATGN"
                     /name="replication initiation protein"
     gene            5737..5928
                     /locus_tag="DLJ83_RS27790"
                     /old_locus_tag="DLJ83_27790"
     CDS             5737..5928
                     /locus_tag="DLJ83_RS27790"
                     /old_locus_tag="DLJ83_27790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_023302508.1"
                     /translation="MTKQQKTALNMAKFIQNQSLLLLEKLNELDLDVEADLCEKLHDDA
                     EHLFRTLSSRLDELQDGN"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            5928..6329
                     /locus_tag="DLJ83_RS27795"
                     /old_locus_tag="DLJ83_27795"
     CDS             5928..6329
                     /locus_tag="DLJ83_RS27795"
                     /old_locus_tag="DLJ83_27795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009310048.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_009310048.1"
                     /translation="MARVSISEAARLTGKSRTTLHRLIKAGDLSTCSGERNAKMVDTSE
                     LLRVFGPFEQPKGEHHSGQVSEQRDTASADQSEQVIRHLKQEIEHLNTLLLSKDSHIDS
                     LKQAMLLLENHQAKLTESPAPWWKFWKKS"
                     /name="helix-turn-helix domain-containing protein"
     gene            complement(6675..6917)
                     /locus_tag="DLJ83_RS29515"
     CDS             complement(6675..6917)
                     /locus_tag="DLJ83_RS29515"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_098963735.1"
                     /translation="MHSAEIHTIQPGEVLFPAFFSSENGERGRNLLRGREALPAQPENR
                     FSAPSGIGFVDGRQSRYGKSPDDSPHDSPAIRIVN"
                     /name="hypothetical protein"
     gene            complement(7283..7915)
                     /locus_tag="DLJ83_RS27805"
                     /old_locus_tag="DLJ83_27805"
     CDS             complement(7283..7915)
                     /locus_tag="DLJ83_RS27805"
                     /old_locus_tag="DLJ83_27805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3226 domain-containing protein"
                     /protein_id="WP_012579086.1"
                     /translation="MKDINNSKKIIFVEGDDDFHFLCNLLEIQGITDVFVEKINGKSKL
                     KQALRAFKNIDSFDEKESIFIILDADTSFSDTERSIIATLRELQISSPSSHNEIAMNGN
                     TKISFFIMPGKDKQGAIEDLIIEHASTRALYEYIIEFFEKIKNNKDDISASDKEYTYPT
                     NEKKAKVQVYLSCNRESDSRIGISMKNGIINTADNCFDEIKDFISKI"
                     /name="DUF3226 domain-containing protein"
     Typing          complement(567..974)
                     /name="ColRNAI_rep_cluster_1987"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="93.399"
                     /coverage="99.0"
                     /evalue="5.92e-171"
     Typing          complement(5209..5616)
                     /name="ColRNAI_rep_cluster_1987"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="95.355"
                     /coverage="99.0"
                     /evalue="0.0"
ORIGIN
        1 caaaatggct tgtttttgtt tatttctgcc atttcttttc tgaatgcttg aatgtttaac
       61 aaaacagccg ggttttttac atcataaaaa caaaaaatag catccagtat agatgttttc
      121 ccgtagttgt ttttcccagc tatgatattt aaagtcttta attgctttag atatagctca
      181 ttgaagcatt tgaagttctt taaacttatt tcctttatca tgatagcctc tgttcgtgtt
      241 tttgttatat gccatacgat ttgttagtac cttaataaaa tgtacagctt tcattgtgat
      301 tagctagact ttatgtcaaa gattaacttt gattgcttgt gttttaatcg atttttttta
      361 ctttcttctt gagattatct ggcagcagcc gtaagcttcc ggctgtgaac gaaaaaaacc
      421 gccttggcgg gcggtttttt cgaaaggttc agtagagttg gcgctctatg aaccgaggta
      481 actggcttaa agggagcgca gtcaccaaaa ctgttcgttt agtttagctt taactggcgt
      541 ataacttcaa gactaactcc ctaaatcagt taccagtggc tgctgccagt ggcgctttgt
      601 cgtgtctttc cgggttggac tcaagacgat agttaccgga ttaggcgcag cagtcggact
      661 gaacgggggg ttcgtgcata cagtccagct tggagcgaac tgcctacccg gaactgagtg
      721 tcaggcgtgg aatgagacaa acgcggccat aacagcggaa tgacaccggt aaaccgaaag
      781 gcaggaacag gagagcgcac gagggagcca tcagggggaa acgcctggta tctttatagt
      841 cctgtcgggt ttcgccacca ctgatttgag cgtcagattc cgtgatgctc gtcagggggg
      901 cggagcctat ggaaaaacgg ccgctgtgcg gcctttcctt ctttcctcca tgcgattact
      961 cggttttctc gagcgtttct acgcatgctc ctgccgctcg ccgcagccga acggcaggag
     1021 cgtagcgact gagtgagcga ggaagcggaa aagaggagat ccctacactg accactgacg
     1081 ctctgaggcc tcttatgacg aaacaacaga aaacagcgct gaacatggct aaattcatcc
     1141 agaatcagtc tctgctcctg ctggagaagc ttaacgagct tgatctcgat gtcgaggccg
     1201 acctttgtga gaaactccac gatgatgcgg agcatctttt ccgtacactg tcctcgagac
     1261 tggatgcatt acaggatggt aactgatggc cagagtgtct attagtgagg ctgcccgact
     1321 gacgggtaag agtagaacaa cactgcacag gttaattaaa gcaggtgacc tgtccacctg
     1381 tagcggtgag cgcaatgcaa aaatggtaga tacttcagag cttttacgtg tctttggccc
     1441 ctttgagcaa ccgaagggtg aacaccattc tggacaggtc tctggacagc gtgatacagc
     1501 ctctgctgac cagagtgaac aggtgatccg tcatctgaaa caggagattg aacacctgaa
     1561 caccttactt ttgtccaagg attcgcacat tgacagcctg aaacaggcca tgctccttct
     1621 tgaaaatcac caggcaaaat taactgaatc cccggcgcca tggtggaaat tctggaaaaa
     1681 atcctgaccc cgtcatgctt cagttttcct ctccggccat cccggggagt tcctgaacct
     1741 tcccaaaaat cgtcagatct ctgaacgctc ctcaccacta aaaataccca caccccacgc
     1801 aaaattaata ttttgcagat ttgtatttaa tatcagtggg ttactttcct gaaatttcgt
     1861 tttttaaatt ttatttatat agatccgact ctatgacgac tcgtcataga gtccccggcg
     1921 agtcgtcata gagtcggtaa cgactcagga ctataaaaac aataagttaa taacgacccg
     1981 actctagaca cgactccccg tttggttgtt ttttagacgc ggcgactctg ggtacgactc
     2041 tagtgaagag tcgccggtga atcgtgtggt gagtcgtccg gcgacttgcc ataacgtgat
     2101 tgccggccgt cgacgaaccc gattcctgaa cgtgctgaaa accggttttc cggctgcgcc
     2161 ggcaacgctt cacggccacg caataaattg cgtccccgtt caccgttttc ggatggaaag
     2221 aacgccggaa acaggactta ctctggctga atggcgtgaa ttttcgcgct atgcacttgc
     2281 gtgcatactc atgcatgccg taaaaacaga gcctgcgcgt ttctggcggg ttttcgggtg
     2341 gtttgttgcc tgttttaccg gttttccgtc agaaacgccc tgaggccgtt ttagcggtgc
     2401 gtacaatcat gcctttatgt taaataacag atgcaaaaaa gccccagaag gggcctgaag
     2461 gttttcctgc taagggacga aacgggccgc ctcccggcgg cctgttcggc agctcccttt
     2521 gcgaccatct tatttggtca gttcagccgt catgtggaca cggttattga actgagcgct
     2581 ggtgattttg tatgacgcac cttgttcagc ggcctgtgcg gcaatttttg cttcagcacg
     2641 atccagggtg gaggcggtag cgctgacgct ctgagcaaaa gcaccgaaag acatcatgga
     2701 tagagcggca actgcaacga aagttttgat ggatttcatg gtcgtattcc ttaagtgatt
     2761 ttgttctgta tggggcgttg ttgccctgat gtgataaatg ataggacgac cattagttga
     2821 ttaaaatcga aacaatttgc ggatatcatt caaaaaaaaa gaacaagaat tgagcgcatc
     2881 aagaccagag gtttatctct ggattttagg taccaaatga ggtggtggat agaaatgtta
     2941 acattgatga ttttatttta acaaattgaa aaataatggt tagtttggcg taatctctct
     3001 tgcttttctc ttgccgaatt tcctaatgtt taggataaga aaaaaaaatc tctatcgatt
     3061 acgtttcttg gctattgcct gttataaaga taacagtaaa atccatgcgt cttgcaggag
     3121 ggtgtgatgg gtaaagagct atctctaaat aaaatttatg ataagaattc tagatatatt
     3181 aatgattcta gagggcatga gctgggaaag gaaaagaaag ttttcgattt tgaagttgaa
     3241 atgattaaaa aaagaagaga ggacgctata aggaagataa ttgaggattc aaaatcatta
     3301 aaatggtaag tgaggtcttt tatgagcctg gctagaaagt taagagaaaa aagaagtaat
     3361 ccgattcata gtgctaacga ggactcctct ggaggggata gcataaacca aataacctcc
     3421 agacagtcta tggatcttgt tataggattt tgcggtgctg ttggctcagg aataaagtca
     3481 attgttgatg tgactgaaga agaactagat gatctaggat atgatgttta tcgcataaga
     3541 gttagcgagc ttatgcaaaa acttttttca gaatggcgtg atgatattgt tactccgttt
     3601 gatagatatc ataagctgca agattttggt gatgcgttaa gaaataaata ttacccacat
     3661 atactatctg aagctgtaat ccatgaaata aaaatagaaa aaggcattga cacctcaagt
     3721 aaaaaaaaca aaaaggcttt tttggtcgat cagttgaagc atcaggatga aattgaactt
     3781 ttaaggatgg tctaccaaca taatttttat ttactaggtg taattagaag tgaagtagaa
     3841 agaaagcgta atcttagaga tgaagggctg agtaagtcag aagtcgatat agttattcat
     3901 cacgatagaa aatcagagag cgattatggt cagcagactg cgaaagctat acttgactct
     3961 gattattttg ttaagaataa tcaaggacaa agggcgcacc ttaaggctaa ggttaagcgt
     4021 tttattggct tgatacatgg gctaaatggt ttaactccaa ccacgtatga aaaaggtatg
     4081 tatgcagctc attcagcatc tctgcaatct gcatgccttt ctcgtcaagt tggtgctgct
     4141 atattggatg ttaatgggaa tctgatttcc gttgggcgta atgatgtacc taaattcaat
     4201 ggtgggcttt atagtgcgga tgatggtgtc aatgatcatc gttgtgtata caaaggtggt
     4261 aaatgttata atgaagttag aaaactaaag attaaaagca aaatttcaca aatacttatg
     4321 tcggaaagcg cttgtgaact tggtgttaaa ttaacagaag atcaagcaga gcaactggct
     4381 gatgtaatat ataaaaaaac accagtatct tctattatag agtactctcg ctcaattcat
     4441 gcagagatgg atgctattac atcattagct agactaggta atggaggttt ttctgataaa
     4501 gttttatata caaccacatt tccttgtcat aactgcgcga gacatattgt cgctgttgga
     4561 ataacaaaag ttgtttatat agagccatat gaaaaaagcc tcgctttaga attgcatgat
     4621 gatgctataa ccgaggtgaa tgagcatggg aaggttatat ttgaatcctt tgaaggtgta
     4681 tcacctcgta ggtatcaaaa attcttcttt tctacagatg aaaggaaaga tagtttcggt
     4741 aacgcagaaa agtactccac taaatataaa aatcacattg atatacagtt tattgatagc
     4801 tatttagatt tcgaaaatcg agtcgttgat atttttagaa ctaacacaaa tattgattct
     4861 ggcaatcatg tcgggagaac tgattcgact attaatttat cttcccagcc cgtaccgccc
     4921 gtaccgcccg taccgcccgt accgtccgta ccgccagtac cgccagtacc accagtacca
     4981 ccagtaccac cagactcgaa atgaagatct gttgactctg atgttataca gagcttaacc
     5041 ttgagacgag aaagaaaaaa accgcctttg cggggcggtt tttttaaggt tctagagttt
     5101 gcggctctat gaaccaaggt aactggctta gaggagcgca gtcaccaaaa cttgttcttt
     5161 cagtttagcc ttaactggcg cataacttca agactaactc ctctaaatca gttaccggtg
     5221 gctgctgcca gtggtgcttt tgcatgtctt accgggttgg actcaagatg atagttaccg
     5281 gataagacgc agcagtcgga ctgaacgggg ggttcgtgca tacagtccag cttggagcga
     5341 actgcctacc cggaactgag tgtcaggcgt ggaatgagac aaacgcggcc ataacagcgg
     5401 aatgacaccg gtaaaccgaa tggcaggaac aggagagcgc acgagggagc catcaggggg
     5461 aaacgcctgg tatctttata gtcctgtcgg gtttcgccgc cactgatttg agcgtcagat
     5521 tccgtgatgc tcgtcagggg ggcggagcct atggaaaaac ggccgctgtg cggcctttcc
     5581 ttttccccat cacgagaccg ctcggttttc tcgagctttt acacgcatgc tcctgccgct
     5641 cgccgcagcc gaacggcagg agcgtagcga ctgagtgagc gaggaagcgg aaaagagact
     5701 gttcttacac tgagcactga cgctctgagg cttcttatga cgaaacaaca gaaaacagcg
     5761 ctgaacatgg ctaaattcat ccagaatcag tctctgctcc tgctggagaa gcttaacgag
     5821 cttgatctcg atgttgaggc cgacctttgt gagaaactcc acgatgatgc ggagcatctt
     5881 ttccgtacac tgtcctcgag actggatgaa ttacaggatg gtaactgatg gccagagtgt
     5941 ctattagtga ggctgcccga ctgacgggta agagtagaac aacactgcac aggttgatta
     6001 aagcaggtga cctgtccacc tgtagcggtg aacgcaatgc aaaaatggta gatacttcag
     6061 agcttttacg tgtctttggt ccctttgagc aaccgaaggg tgaacaccat tctggacagg
     6121 tctctgaaca gcgtgataca gcctctgctg accagagtga acaggtgatt cgtcatctga
     6181 aacaggagat tgaacacctg aataccttac ttttgtccaa ggattcgcac attgacagcc
     6241 tgaaacaggc catgctcctt ctcgaaaatc accaggcaaa attaactgaa tccccggcgc
     6301 catggtggaa attctggaaa aaatcctgac cccgtcatgc ttcagttttc ctctccggcc
     6361 atcccgggga gttcctgaac cttcccaaaa atcgtcagat ctctgaacgc tcctcaccac
     6421 taaaaatacc cacaccccac gcaaaattaa aattttgcag attccttatt tacaacaatg
     6481 ggttaatgaa aaataaatgt gcggtgatgt gttacaaagt gcagatccaa gtcgtggacg
     6541 actctatggc gaatcgctga cgaattgccc acgattcata tgtgaatcac gctttattat
     6601 catattgtta tgatgaatcg actcttgatt caattcatca ctttgggtgt tttttgctca
     6661 tggtgactct tgattcaatt cacgattcga atcgccggtg aatcgtgtgg tgagtcgtcc
     6721 ggcgacttgc cataacgtga ttgccggccg tcgacgaacc cgattcctga aggtgctgaa
     6781 aaccggtttt ccggctgcgc cggcaacgct tcacggccac gcaataaatt gcgtccccgt
     6841 tcaccgtttt cggaggagaa gaacgccgga aacaggactt cccctggctg aatggtgtga
     6901 atttccgcgc tatgcacttg cgcgcatact catgcatgcc gtaaaaacag agcctgcgcg
     6961 tttctggcgg gttttcgggt ggtttgttgc ctgttttacc ggtttcccgt cagaaacgtc
     7021 ctgagtccgt tttagcggtg cgtacaatta tgattttatg ttaaattgtt ttaagtgaat
     7081 agagagaata taacttaagg gagcatcttg tgctgggtct tttacattag atctgcacaa
     7141 tcattgtttt ggcatctggt gatgtcttta ggacgtttga gattgctgat aactaaagtg
     7201 tatgatgctt tctatacgtt atccggcgtt taataacacc ctggtgataa gccagcccgt
     7261 gaagggctgg cttgatttgg atttatattt ttgaaataaa atcttttatt tcatcaaagc
     7321 aattgtctgc tgtgtttatt attccatttt tcatggatat tcctattctt gagtcggatt
     7381 ctctattgca gctaagatag acttgtacct tagctttttt ttcgtttgtt ggataagtgt
     7441 actctttgtc actcgctgag atgtcatctt tattattttt aattttttcg aaaaattcta
     7501 ttatgtattc atataacgct cgagtgcttg cgtgttcaat tatcagatct tcaatggcac
     7561 cttgcttgtc ttttcctggc attataaaga aagaaatttt tgtattgcca ttcatagcta
     7621 tctcgttatg cgagctgggg gaggagattt gtagttctcg caatgtggca attattgatc
     7681 tttctgtgtc agaaaatgat gtgtcagcat ctaatataat aaaaatactt tctttttcat
     7741 cgaaagaatc aatgtttttg aatgctctaa gtgcttgttt taattttgat tttccattta
     7801 ttttttcgac aaaaacatcg gtaatgcctt gtatttcaag taggttgcat agaaaatgaa
     7861 aatcatcatc accctcaacg aaaatgatct ttttgctatt atttatgtct ttcattatct
     7921 tacctcccag tcgttctcaa ctgagtagga gaaatcatcc atattgaatt gtacggctgt
     7981 tggttttagg gagttctttt ctcttcctag tctaatataa gcgatatctt catttttgct
     8041 atctatttcg tttattgctc gtatcacatc ttgactatga gttgttgcaa atatttgatt
     8101 gttgttttgt tttgcagatg aaattaatga ttttattatg tctttaatta ctgagtaatg
     8161 tattccgttc tcgatttcat caataagaat aattgagttt tcctgtacca gcactgagct
     8221 gataaaagat aatgctcgac tgataccctc gccaagcatt gatatttcat ttagctcact
     8281 aaatccaatg tctaaatata tttccttatt gttacctatc gcagatattg ctatatctac
     8341 aattctgtca tctatttttt ttaagttttc tagtatgtct tttttccttt tttgtgttag
     8401 taggctagat acatttgtaa ttgttgcctc tttgtttatc tttctggatg ttgttattat
     8461 tgttgctgtc ttaaatttat aattaatccc atccctttcg ttttttattt cggattttat
     8521 ttctacgcca tcttctttca attgcataga gaaaagctta ttggaaaccc tgtttttcgc
     8581 attgggtgtc tcggtcacat ttatttttaa agagtttact gtggcctgag aaccgatagt
     8641 ttgacgaggt atgttttggt tagatagtac ggtgtcaacg tttagagaca aacttgattc
     8701 taatctctga tttgtttctg tttcatatgt ttgtgttact tcagagcgtt catctcgaat
     8761 gactatggac atcttttgtg atgtgtccat atcatgaaag taactaacc
//
