LOCUS       NZ_CP029572             8771 bp    DNA     circular CON 04-JAN-2024
DEFINITION  Acinetobacter baumannii strain DA33098 plasmid pDA33098-9-2,
            complete sequence.
ACCESSION   NZ_CP029572
VERSION     NZ_CP029572.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN09241862
            Assembly: GCF_003181015.1
KEYWORDS    RefSeq.
SOURCE      Acinetobacter baumannii
  ORGANISM  Acinetobacter baumannii
            Bacteria; Pseudomonadota; Gammaproteobacteria; Moraxellales;
            Moraxellaceae; Acinetobacter; Acinetobacter calcoaceticus/baumannii
            complex.
REFERENCE   1  (bases 1 to 8771)
  AUTHORS   Nicoloff,H., Hjort,K. and Andersson,D.I.
  TITLE     High prevalence of unstable heteroresistance caused by gene
            amplification in clinical bacterial isolates
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8771)
  AUTHORS   Nicoloff,H., Hjort,K. and Andersson,D.I.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2018) Department of Medical Biochemistry and
            Microbiology, Uppsala University, Husargatan 3, Uppsala 75442,
            Sweden
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: CLC Genomics workbench v. 11.0.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 150.0x
            Sequencing Technology             :: PacBio; Illumina HiSeq 2000
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/04/2024 17:52:17
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,109
            CDSs (total)                      :: 4,014
            Genes (coding)                    :: 3,922
            CDSs (with protein)               :: 3,922
            Genes (RNA)                       :: 95
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 29 of 92
            Pseudo Genes (incomplete)         :: 55 of 92
            Pseudo Genes (internal stop)      :: 15 of 92
            Pseudo Genes (multiple problems)  :: 7 of 92
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP029572.1.
            Bacteria and source DNA available from Dan I. Andersson.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..8771
                     /organism="Acinetobacter baumannii"
                     /mol_type="genomic DNA"
                     /strain="DA33098"
                     /serotype="ST350"
                     /host="Homo sapiens"
                     /db_xref="taxon:470"
                     /plasmid="pDA33098-9-2"
                     /geo_loc_name="Spain"
     gene            complement(join(8767..8771,1..821))
                     /gene="blaOXA"
                     /locus_tag="DLD53_RS20600"
                     /old_locus_tag="DLD53_20595"
                     /pseudo=""
     CDS             complement(join(8767..8771,1..821))
                     /gene="blaOXA"
                     /locus_tag="DLD53_RS20600"
                     /old_locus_tag="DLD53_20595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_057689930.1"
                     /GO_function="GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="OXA-24 family carbapenem-hydrolyzing class D
                     beta-lactamase"
                     /name="blaOXA"
     gene            complement(1536..1946)
                     /locus_tag="DLD53_RS20610"
                     /old_locus_tag="DLD53_20605"
     CDS             complement(1536..1946)
                     /locus_tag="DLD53_RS20610"
                     /old_locus_tag="DLD53_20605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005207185.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_075911385.1"
                     /translation="MLNFELKEKWGENSLILGFTQIPTTLIYAQKELGLSSIEINILLN
                     LLTHWWKKEEFPYPSQAGIAYRMGVSTRTVQRTLAGLETKGFITRNKTSRDNSKYKGRS
                     IYDLSPLVKILEEKAPDLDIVKKIKKNKRLAK"
                     /name="helix-turn-helix domain-containing protein"
     gene            2097..2417
                     /locus_tag="DLD53_RS20615"
                     /old_locus_tag="DLD53_20610"
     CDS             2097..2417
                     /locus_tag="DLD53_RS20615"
                     /old_locus_tag="DLD53_20610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005207183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_012780178.1"
                     /translation="MFTRTVQTLKNSTDLVQRFTMPNIRQTFELRRFSEKEKNKQYILI
                     FKDIILNKKDWDDVKVVAEIQERNNSLRFSIKASKQYPELTSYEKMLEAKINDIIKPTL
                     VA"
                     /name="hypothetical protein"
     gene            2436..3170
                     /locus_tag="DLD53_RS20620"
                     /old_locus_tag="DLD53_20615"
     CDS             2436..3170
                     /locus_tag="DLD53_RS20620"
                     /old_locus_tag="DLD53_20615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005207180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_075911386.1"
                     /translation="MTPPHILLEENYNKPLIPLPVYFSYENILESKYFYNQREGGIFCL
                     KELQASEGSEYSGCIELFYCEFNNEYALDGVCAVADEYLDEYDAANKALEAYEVEKEIL
                     IARYAFKDIEIINDSIKITGKQIKGASILANYQRNGVSSFIYKYLLKKYGVLVCDNYQT
                     YKGHMLWVLSIVKLSVIRIYDLTKKEFIGTFDKVSPCLIKPWSVPYNFPSDKEKFLRLD
                     ACVYTELEFHSLVLVTFAEDMF"
                     /name="hypothetical protein"
     gene            complement(3259..3477)
                     /locus_tag="DLD53_RS20625"
                     /old_locus_tag="DLD53_20620"
     CDS             complement(3259..3477)
                     /locus_tag="DLD53_RS20625"
                     /old_locus_tag="DLD53_20620"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_075911387.1"
                     /translation="MAAAEKKQSANPAMEAAKEAANIKIDGFEQGVNTYNAIGSQLLRE
                     KRDPSVINKTRENRRNIRKAREAIKNL"
                     /name="hypothetical protein"
     gene            complement(3446..3844)
                     /locus_tag="DLD53_RS20630"
                     /old_locus_tag="DLD53_20625"
     CDS             complement(3446..3844)
                     /locus_tag="DLD53_RS20630"
                     /old_locus_tag="DLD53_20625"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_075911388.1"
                     /translation="MSNIIEFKRNERRFINQKPISPVELVTNILTPQEVDIKSLIKETK
                     KILREKGLKFRTSHQDLEHLKGNNLILFSKKKCGFILTTKLACSTNSSWEIYSISIDKT
                     TKALDIVNKIISRLGDNVHGSSREEAIS"
                     /name="hypothetical protein"
     gene            3938..4213
                     /locus_tag="DLD53_RS20635"
                     /old_locus_tag="DLD53_20630"
     CDS             3938..4213
                     /locus_tag="DLD53_RS20635"
                     /old_locus_tag="DLD53_20630"
                     /inference="COORDINATES: protein motif:HMM:NF015807.4"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Arc family DNA-binding protein"
                     /protein_id="WP_075911389.1"
                     /translation="MIKKYTQVNFRLPLDLKEEIEQSASLTGNSITAEIVERLRNSFEY
                     DNLMLDNIELQSELINLESEKLDLLLEYQDKLCKIQDQILEELKKK"
                     /name="Arc family DNA-binding protein"
     gene            complement(4288..5046)
                     /locus_tag="DLD53_RS20640"
                     /old_locus_tag="DLD53_20635"
     CDS             complement(4288..5046)
                     /locus_tag="DLD53_RS20640"
                     /old_locus_tag="DLD53_20635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017393773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_015060804.1"
                     /translation="MALDKSKKRGRPAQLLQIAELHAFVDYLSQKKDRSDLQNDVIAML
                     RIEKFNFESLSEAEQILVKEALKPYREHMKLNLLFDEVSVKYPQTAYERKFVQLFEAYR
                     DNALSGADFNILKTMATRYLSFKAHKLELSDLELYLSQIQKKEASKKRTAENHRKFELG
                     GAVLAAFKELGIDISQDTPEQMKNRIQNTKKFHDDVMKSKIYQEVKSYKNGYFERNKLF
                     HQVLEGLNTWKKDGELLSVIEIKKALVKNQ"
                     /name="hypothetical protein"
     gene            5350..6519
                     /locus_tag="DLD53_RS20645"
                     /old_locus_tag="DLD53_20640"
     CDS             5350..6519
                     /locus_tag="DLD53_RS20645"
                     /old_locus_tag="DLD53_20640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002011489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /protein_id="WP_012846858.1"
                     /translation="MASYHFSVKSKNKGYALSHYLYISRLMQYEGIRKKSAEVLEHVEP
                     GQCMPSWVKDPVEFWQAADTFERANAKAYMEYEIALPNEFTVEQRKTLVETFVDKTIAT
                     HHYPHSYAIHNVKSRLSGEEQPHCHLMFSLKADDGIERSPEQYFKRYNAKEPSKGGAKK
                     IQLQDGHADYTTYLLHIRKAWENHLNDALAEHSPTVTYQIDGQKIQIKNQVSADNYEKY
                     NEIHGTLYLPEPKLGTGKQNETVEYLAEIQKIRQHNAKERELEQRQQYFDQQHEYYYSC
                     SNEPFSSPEVMHYLNHLIKKASNKKELGHDIDEIIQTQQPILHHEKWDIDTINFNLNNA
                     RLYPEPDMEFKVRSVQPKPVIEPTSPKSKPEIQPSQPEPKRNDYDGPGF"
                     /name="MobA/MobL family protein"
     gene            7057..7944
                     /gene="repM"
                     /locus_tag="DLD53_RS20650"
                     /old_locus_tag="DLD53_20645"
     CDS             7057..7944
                     /gene="repM"
                     /locus_tag="DLD53_RS20650"
                     /old_locus_tag="DLD53_20645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360254.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein RepM"
                     /protein_id="WP_012780181.1"
                     /translation="MDKNQIVKSNQVIEASYQLSAVEQRIVLAAISRIPKSQPITDDEL
                     YPVSVNELQLLGVHEKTAYRDLKEGINRLYERSINLSIDDKSIKMRWVQEIQFLDSQSI
                     IGIRFSKPILPFISNLSREFTKYALSDIAGINSGYGIRIYELLVQYRQIGKREISVENL
                     RSMLELGKKYPLFADFKKRVIDTAVDQINECSPLSVSYEQKKTGRKVTHIQFSFKEKSK
                     SINHLNEPEKFYKLTDAQVHMFGNQLSRLHELSHLATQGESYDDLAATIKEMLRDPIQQ
                     KQFIPHLRNLGFKG"
                     /name="repM"
     gene            8021..8578
                     /locus_tag="DLD53_RS20655"
                     /old_locus_tag="DLD53_20650"
     CDS             8021..8578
                     /locus_tag="DLD53_RS20655"
                     /old_locus_tag="DLD53_20650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017398013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid replication DNA-binding protein"
                     /protein_id="WP_012780177.1"
                     /translation="MKSLSVIELSNLYGMTRQAVYKQINKGNLSKNSDGKIDLSEAIRV
                     FGEPSKYVNSLQTTETRKLSEVHLLEQQVHMLQKQLEQAHEREKFQRDELKAKNDQLHV
                     KDEQIEAMQRLLEAPKTNMTTFADQKPSQDIATDPRPEPEPKHDGLTTPVEIENKRIPV
                     PEQVELEQPKRGWLSRFFLPNG"
                     /name="plasmid replication DNA-binding protein"
     ARG             complement(3..157)
                     /name="OXA-207"
                     /gene="OXA-207"
                     /gene_name="OXA beta-lactamase; OXA-24-like beta-lactamase"
                     /tool="rgi"
                     /drug_class="carbapenem; penam"
                     /identity="100.0"
                     /coverage="18.91"
     ARG             complement(106..821)
                     /name="OXA-160"
                     /gene="OXA-160"
                     /gene_name="OXA beta-lactamase; OXA-24-like beta-lactamase"
                     /tool="rgi"
                     /drug_class="carbapenem; penam"
                     /identity="95.78"
                     /coverage="86.55"
     Typing          7058..7944
                     /name="rep_cluster_1364"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          5429..6516
                     /name="MOBQ"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 tgattccaag attttctagc gacttataag taatttcatt acgaatagaa ccagacattc
       61 cttctttcat ttctaagttg agcgaaaagg ggattttttt tccattagct tgctccaccc
      121 aaccagtcaa ccaacctacc tgtggagtaa cacccattcc ccccactttt tgcataaatc
      181 ttactaccat ttacttcttt aattagaagc atttttttaa cttcttcttg agtttctaat
      241 ttaaaaggta atcggttatg tgcaaggtca tcggcaaaat taacttcttg tactggtgta
      301 attttaaggg ggccaactaa ccaaaaatta tcgacctgtg ttccaatatt tgtatttcca
      361 aaattaaccc gctttacttc tttctgcatt agctctaggc cagtccgtct tgcaagctct
      421 tgatatactg gaactgctga caatgccatt gcctcaccta aagtcatatc tttctcccac
      481 ataggataag ttcttttttt accatcccat ttgaaaatct catttgttgt tgctttatga
      541 ttttctagcc cgattaaagc atttagcatc ttaaatgttg atgcagggac atattcttta
      601 tttgctcgtg caagagcatt accataggtg ctaagatttt taccctcttt aataataatt
      661 acaccctgtg tttgagcttc atcaaaatag cttttaatag ctttttcatg ttgctgagaa
      721 gaaatatgaa aattatcttc agatttagtt ttaatagatg aacatgcact gagagaaact
      781 agaatagaaa tgctgaatat aggaagtata aattttttca ttacaaattc atgttagggg
      841 aaattttggg gcttagagta taatattttt attaaaaaag ttaaaactct tttaatttaa
      901 cataatgggc gttatgcgaa ataaattatg aaaagttatt attttttaat tatttataga
      961 attagtcatg actaaaaaat aggtgaaaag ccgacttgga aacaagtcgg atgcttttta
     1021 agcaactttg tcacttttag ccaacaaaat cgattaaaaa atactcaaaa atttaatttt
     1081 tcctgatttc tcaatgctcc aataacccac ttttatcccc atttcctgcg gacaaacatc
     1141 gggataattt cccaagtcaa ttgtaaagta gagaacaaaa aaactgtaaa gaggatttgg
     1201 aacaataaaa aagtgacctt ttaaagggga tttacaattg gactttattc tttattaggt
     1261 tttaaaacat gtttgagctc gatccaatgg tagaagaaat taatgcattt ctagctctaa
     1321 gaggttatcc acctttttct gatataaacc aattcacatc cgaacaatgg tttgattttt
     1381 cacaaattgc tatgtaccag tatcgcaaca tagctctatg gcatattttc aggcaattag
     1441 gtatacaaac atcaccgaag attcatatag ttagatagaa aaagggagct ttaagctccc
     1501 ttttttgact tatcgtaaga gattttatgt taaatctatt tagctagtct tttatttttt
     1561 ttaatttttt tcacaatatc tagatcaggt gccttttctt ccagaatttt tactaatgga
     1621 gataaatcat aaatactcct tcctttgtat ttactgttat ctcttgatgt tttgtttctg
     1681 gttatgaatc cttttgtttc aagacctgct aatgttcgtt gtacagttct agtagaaact
     1741 cccattcgat atgcaattcc agcttgagat ggataaggaa attcttcttt cttccaccaa
     1801 tgggtcaata agttaagtaa gatgttaatt tctatagatg atagaccaag ctctttttgt
     1861 gcataaatta gagtagttgg gatctgcgtg aaccctaata ttagagagtt ttcgccccac
     1921 ttttctttta attcaaaatt taacataatt ttttaaaacc ctattcatat atatatataa
     1981 attaatatat atatagtacg ccaaatttga cgtagttgat agtgacatat ttgtcttata
     2041 acctgtcact atatattttt attttctttt atttctttag gtatgtaggt gtcaaaatgt
     2101 tcactagaac tgttcaaacc ctcaaaaata gtactgattt agttcagcgt tttactatgc
     2161 ctaatattcg tcaaacattt gaactaagac gtttttctga gaaagaaaaa aataagcaat
     2221 atatacttat tttcaaagat attattctca ataaaaaaga ttgggatgat gtgaaagttg
     2281 tagctgaaat tcaagaaaga aataatagct taagattttc tattaaagca tccaaacagt
     2341 atccagaatt aacttcttat gagaaaatgt tagaagctaa aattaatgat attattaaac
     2401 caacattagt agcttgatga aatataaggt ttaaattgac tcctccacac atacttctcg
     2461 aagaaaatta taataagcct ttaattccac tacctgttta cttttcttat gaaaatattc
     2521 ttgaaagtaa gtacttctac aaccaaaggg aaggtggaat attttgttta aaagaattgc
     2581 aagcttcaga aggtagcgag tattctggat gtattgagct tttttattgt gaatttaata
     2641 atgagtatgc attggatggg gtttgtgctg ttgctgatga atatttagat gaatatgacg
     2701 ctgctaataa agccttagaa gcttatgaag tagagaaaga aattttgata gcgagatacg
     2761 catttaaaga tatcgaaatt attaatgact ctattaaaat aacaggtaaa caaataaaag
     2821 gtgcatcgat tttagccaat tatcagcgaa atggagtttc ctcatttata tacaaatact
     2881 tattaaaaaa gtatggtgtg ctggtttgtg ataattatca gacctataag ggccacatgc
     2941 tttgggtttt gagtattgtt aagttaagtg taatcagaat ttatgattta actaaaaagg
     3001 aatttattgg aacttttgat aaggtaagtc cttgtttaat aaaaccttgg tctgtacctt
     3061 ataattttcc atctgataag gaaaaatttc ttagactaga tgcttgtgta tatacggaat
     3121 tggagtttca cagccttgtt ttagtcactt ttgcagaaga catgttctga taatttttat
     3181 catgaacaaa gccctgagaa tttcttaggg cttgtttaat gagaattttt tatattttag
     3241 atcttaagaa gctttttact ataaattctt gatagcttct cgtgcttttc gaatatttcg
     3301 tctattttca cgagttttat taattacact tggatctcgc ttttctcgca ataattgtga
     3361 accaatcgca ttgtaggtat ttacaccttg ctcaaagcca tcaattttaa tatttgctgc
     3421 ctctttcgct gcttccatcg ctggattagc tgattgcttc ttctctgctg ctgccatgaa
     3481 cgttatctcc tagcctagat ataattttat taacaatatc taatgctttc gtcgtcttat
     3541 ctatacttat ggaatatatt tcccatgagc tatttgtgct acaggctaac tttgtggtta
     3601 agataaaccc gcatttcttt ttggaaaata atattaaatt atttcctttt aagtgttcca
     3661 aatcttgatg agaagtacga aattttaagc ctttttctct taaaattttc tttgtttcct
     3721 taatcaaaga ctttatatct acctcttgtg gagtgagtat atttgtcact agttctacag
     3781 gactgatagg tttttgatta ataaatctcc tttcatttct tttaaattca ataatgttgg
     3841 acatatatag ctactccaaa tgttatagca catttgctat aataatatat agcaaatgtg
     3901 ctatagttat tcaagacatt ttagactcta gaatttcatg attaaaaagt atacccaggt
     3961 taattttaga cttcctcttg atttaaaaga agaaatagaa cagtcagcta gtcttactgg
     4021 taattctatt acagcagaaa tagtagaaag actcaggaat agttttgaat acgataattt
     4081 gatgcttgac aatatagagt tacaaagcga attaattaat ttagagtctg agaaattaga
     4141 tttactttta gaataccaag ataaattatg taagatacaa gaccaaattt tagaggaatt
     4201 aaagaaaaaa tagatttaag gttttctaaa attaacataa tacgccttat gcgaaatttg
     4261 cctgaatagc ctttctcaga aaggctatta ctgatttttc actaaagctt tcttaatttc
     4321 gatgactgac aataactctc cgtctttttt ccaggtattc agtccctcta atacctgatg
     4381 aaaaagctta tttctttcaa aatatccatt tttataactt ttaacttctt gatatatctt
     4441 agatttcatt acatcatcat gaaatttttt cgtattctga atgcgattct tcatctgttc
     4501 aggcgtatct tgactaatat caatccctaa ctccttgaaa gcagctaaca cagcaccgcc
     4561 caactcaaac ttacgatgat tttcagccgt tctttttttg ctggcttcct tcttctggat
     4621 ctgactcaaa taaagctcta aatcactcaa ctcaagctta tgcgctttga aactcagata
     4681 acgagtcgcc atggttttca agatattaaa atcagcacca ctcaacgcat tgtcccgata
     4741 agcctcaaac aactgcacaa acttccgttc atatgcggtc tgcggatact tcacagacac
     4801 ctcatcaaac aataagttca gcttcatatg ctcacgataa ggttttaagg cctctttcac
     4861 caagatctgt tcagcttcag acaatgactc aaagttaaat ttttcaattc gtagcattgc
     4921 aatcacatca ttctgcaaat cagaacgatc cttcttctgt gaaagatagt ctacaaatgc
     4981 atgtaactct gcgatttgta aaagttgtgc aggtctgcca cgtttttttg atttatccaa
     5041 tgccatctat ctgccgccta attttcagaa ctgctaccga ttgagttatg gttttaccat
     5101 aattcaatcg ggcagtctga aaataattat ttaaaataaa aataaaattt cttgaaaaga
     5161 atttatattt ttattttaaa taattcgcac ttgacagttt ctcctaatcg gagaaactag
     5221 tacgcaatgg ggcgattccc ccttgacccc ctttaaccgg attatttcag ccctgtaggc
     5281 attacataat ccggagattt ttattgcgtt tcactccata aaaaccaaca acaccccaag
     5341 gaagtgaaca tggccagtta ccatttcagc gtcaaaagta aaaataaagg ctacgcactg
     5401 agccactacc tgtacatttc ccgactcatg caatacgaag gcatccgcaa aaagagtgca
     5461 gaagtcctcg aacatgtcga accagggcaa tgcatgccct cctgggtcaa agatccggtt
     5521 gaattctggc aagcagcgga cacctttgaa cgggccaatg ccaaggctta catggaatac
     5581 gaaattgccc taccgaatga attcaccgta gaacaacgta aaacgctcgt agagacattt
     5641 gttgataaaa ccatagcaac acaccactac cctcattcct acgccataca caacgtaaaa
     5701 tcacgcctca gtggtgaaga acaaccccat tgccacctca tgttttcact caaagccgat
     5761 gacggcatag aacgaagtcc ggaacaatac ttcaaacgct acaacgctaa agaaccaagc
     5821 aaaggcggag caaagaaaat tcaactacag gatggccatg ccgactacac cacttacctc
     5881 ctacatatcc gaaaagcctg ggaaaatcac ctgaatgatg cattggcaga acatagccca
     5941 accgtgactt accagatcga tggccagaag atccaaatta aaaaccaagt ttcggcagac
     6001 aactacgaaa aatacaacga gatacacggc accctctacc taccagaacc caaactgggg
     6061 acaggcaaac aaaatgaaac cgtggaatac ctagcggaaa tccagaaaat cagacaacac
     6121 aatgccaaag aacgagaact ggaacagcgc caacaatact ttgatcaaca gcatgaatac
     6181 tactacagct gctcaaacga acccttcagt tctccggaag tgatgcacta cctcaatcac
     6241 ctcattaaaa aagccagtaa caaaaaagaa ctgggccacg atatcgacga aattattcaa
     6301 actcagcaac caatcctgca tcacgaaaaa tgggatatcg ataccatcaa ttttaatctc
     6361 aataacgcca ggttataccc agaaccggat atggagttta aagtccgatc cgtacaacca
     6421 aaaccagtga ttgaaccaac atcaccgaag tcaaaacctg aaatacaacc ctcacagcct
     6481 gaaccgaaac gaaatgatta tgatggtccg ggtttttaaa aatggatcta gatcagaaag
     6541 tacaaagcga gtgtctacga gcgacatcac caaaattagc gcctcgactt tctgaaaaac
     6601 cgctttttaa ggctgtatag cctaaaaaag cataaatcag atgctaaaac tggcttccag
     6661 accgagcgaa gcgagcaaaa agctttatga gcgaagcgaa ttccgagttg cttttgctct
     6721 tgcctttact ttttctcaaa ttcacgaagg aattaacaga aaaattgccc cctgaatcga
     6781 gcgaaagcga gattcaatag agtttgagcg tagcgaaaac cacgggcaat tttttcaaac
     6841 gtctttttta attattttta tatcttttaa atcttttctt tgagctgtat cccttatgga
     6901 gcaagccttt caaagtttaa ctatgacgga ttgactacta actatgacgg attgactact
     6961 aactatgacg gattgactac ttaactatga cggattgact actaactatg acaagtatat
     7021 agttgtcata tataaaagaa aatcaatggt tttattttgg ataagaatca aattgttaaa
     7081 tcaaatcaag ttatagaagc ttcctatcaa ttaagtgctg tagaacagcg tatcgtcttg
     7141 gcagctattt cacgtattcc gaagagccag cctattactg atgatgagtt ataccctgta
     7201 agcgttaatg aactacagtt attaggagta catgaaaaaa ccgcatacag agacttaaaa
     7261 gaaggaatta atagacttta tgaaagatct attaatctta gtattgatga taaatctata
     7321 aaaatgaggt gggtacaaga gatccagttt ttggatagtc aaagtatcat tggtattcgt
     7381 ttttcaaaac ctatcttgcc cttcatatct aatttaagta gagaatttac taagtatgct
     7441 ctatcagata ttgctgggat caatagtgga tatggtattc gtatttatga attattggtg
     7501 caatacagac aaataggtaa gcgtgaaatc tctgttgaga acttacgaag catgttggag
     7561 cttggcaaaa aatacccact atttgcagat ttcaaaaaac gggtaattga tactgctgta
     7621 gaccaaataa atgaatgcag cccattaagc gtttcctatg agcaaaaaaa aactggtcgt
     7681 aaagtcactc atattcagtt ttcatttaaa gaaaagtcca aaagcattaa tcatctcaat
     7741 gagccagaga agttttataa attaactgat gctcaagtcc atatgtttgg caatcaactt
     7801 tctcgtctac atgaactatc tcatttagcg actcaaggag aaagttacga tgatctagct
     7861 gcaacaatca aagaaatgct aagagatcca atacaacaaa agcaatttat tcctcatctt
     7921 aggaatttag gttttaaagg atgatgtttg attgtgtatg tagcggttga ctgtttcttg
     7981 atgtatctta gttcacataa tagacaacct aaattacaac atgaaatcac tatctgttat
     8041 cgagctttca aacctctatg gaatgactcg tcaagccgtt tataaacaaa taaataaagg
     8101 taatttaagt aagaatagtg atggtaaaat tgatctttct gaggccattc gtgtctttgg
     8161 tgagccatct aaatatgtaa acagtttaca gacaaccgaa acacgaaagt tgtcagaagt
     8221 tcacttactt gaacagcagg ttcacatgct tcaaaaacag cttgaacaag ctcatgagcg
     8281 tgagaagttt caacgagatg aattaaaagc taagaatgat cagttacatg ttaaggatga
     8341 acaaattgag gctatgcaac gcttattaga agccccaaaa accaatatga ctacgtttgc
     8401 cgatcagaaa cctagccagg atatagcaac ggatcctcga ccagaaccag agccgaaaca
     8461 tgacggattg actactccag ttgaaataga aaataagcgg attccagtgc cggagcaggt
     8521 tgaactggag cagccgaaaa gagggtggtt aagccggttt ttcttaccta atgggtaaaa
     8581 ggcttgttta ggtgtactaa tcaaagttgt gaaacattac tcaaataata ggcgtggaac
     8641 gtgaataatc atgaaaaagc cgttctagtg cgctgaactc tagaacggct ttgactaaac
     8701 tattgatgct tataagaaaa tttcaagcat ttcgcataag gcgtattatg ttaattttag
     8761 aaattattaa a
//
