LOCUS       NZ_CP028795             5596 bp    DNA     circular CON 09-JAN-2024
DEFINITION  Klebsiella pneumoniae strain WCHKP040035 plasmid p2_040035, complete
            sequence.
ACCESSION   NZ_CP028795
VERSION     NZ_CP028795.2
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN08624668
            Assembly: GCF_003037325.3
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 5596)
  AUTHORS   Tang,G., Long,H., Feng,Y. and Zong,Z.
  TITLE     The complete genome of Klebsiella pneumoniae strain WCHKP040035
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5596)
  AUTHORS   Tang,G., Long,H., Feng,Y. and Zong,Z.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-AUG-2019) Center of Infectious Diseases, West China
            Hospital, Sichuan University, Guoxuexiang 37, Chengdu, Sichuan
            610041, China
  REMARK    Sequence update by submitter
REFERENCE   3  (bases 1 to 5596)
  AUTHORS   Tang,G., Long,H., Feng,Y. and Zong,Z.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-APR-2018) Center of Infectious Diseases, West China
            Hospital, Sichuan University, Guoxuexiang 37, Chengdu, Sichuan
            610041, China
REFERENCE   4  (bases 1 to 5596)
  AUTHORS   Liu,L., Lin,J., Tang,G., Yang,B., Feng,Y. and Zong,Z.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-FEB-2018) Center of Infectious Diseases, West China
            Hospital, Sichuan University, Guoxuexiang 37, Chengdu, Sichuan
            610041, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.4
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200.0x
            Sequencing Technology             :: Illumina HiSeq; MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/09/2024 02:30:26
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,546
            CDSs (total)                      :: 5,424
            Genes (coding)                    :: 5,299
            CDSs (with protein)               :: 5,299
            Genes (RNA)                       :: 122
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 11
            Pseudo Genes (total)              :: 125
            CDSs (without protein)            :: 125
            Pseudo Genes (ambiguous residues) :: 0 of 125
            Pseudo Genes (frameshifted)       :: 47 of 125
            Pseudo Genes (incomplete)         :: 81 of 125
            Pseudo Genes (internal stop)      :: 12 of 125
            Pseudo Genes (multiple problems)  :: 15 of 125
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP028795.2.
            On Aug 18, 2021 this sequence version replaced NZ_CP028795.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..5596
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="WCHKP040035"
                     /host="Homo sapiens"
                     /db_xref="taxon:573"
                     /plasmid="p2_040035"
                     /geo_loc_name="China: Chengdu, Sichuan"
                     /collection_date="2017-06-15"
     gene            complement(244..402)
                     /locus_tag="C6M51_RS27830"
     CDS             complement(244..402)
                     /locus_tag="C6M51_RS27830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_071596352.1"
                     /translation="MHEPPVQPDCCALSGNYHLESNPDGHAKTPLAAAIGNWIYTREIL
                     RGLEVGA"
                     /name="replication initiation protein"
     gene            1042..1218
                     /locus_tag="C6M51_RS00275"
     CDS             1042..1218
                     /locus_tag="C6M51_RS00275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004197757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004197757.1"
                     /translation="MQKPKKKPLVVKKRSWHPAVMANLMRQAQEEDYRREQMAELERSA
                     RSHFADIGGEDGG"
                     /name="hypothetical protein"
     gene            1208..1552
                     /locus_tag="C6M51_RS00280"
                     /old_locus_tag="C6M51_00300"
     CDS             1208..1552
                     /locus_tag="C6M51_RS00280"
                     /old_locus_tag="C6M51_00300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006122514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="WP_062955149.1"
                     /translation="MAVKRTRFLGIRVTDGEYQQLLERCNGRQLAVWMRETCLDTRPAR
                     SLRLPSIDPVLLRQLAGMGNNLNQIARKINGGQWSGADRVQVVAALMAIDAELERLRHA
                     VLEKGADDDR"
                     /name="MobC family plasmid mobilization relaxosome protein"
     gene            1761..>2195
                     /locus_tag="C6M51_RS27760"
                     /pseudo=""
     CDS             1761..>2195
                     /locus_tag="C6M51_RS27760"
                     /inference="COORDINATES: protein motif:HMM:NF015397.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /name="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            2230..2739
                     /locus_tag="C6M51_RS00290"
                     /old_locus_tag="C6M51_28580"
     CDS             2230..2739
                     /locus_tag="C6M51_RS00290"
                     /old_locus_tag="C6M51_28580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020325392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeB family mobilization protein"
                     /protein_id="WP_032433972.1"
                     /translation="MNSLLTLAKDLEQKSKAQQQSTGEMLKAAFSEHEKSVRAELSESG
                     KRISAAIRAHEQGMSAAMQSNRLSVMRMVGRTWLTITMVSGLLFASLSGVLWYQGSLIA
                     SNLAEIDRQNAALSKLNAKTWGVTYLEDSNGRFLVLPKGTAVDRTQSWTVGNGRSKQNA
                     LRLVKE"
                     /name="MbeB family mobilization protein"
     gene            2746..2958
                     /locus_tag="C6M51_RS00295"
                     /old_locus_tag="C6M51_28585"
     CDS             2746..2958
                     /locus_tag="C6M51_RS00295"
                     /old_locus_tag="C6M51_28585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeD family mobilization/exclusion protein"
                     /protein_id="WP_021527181.1"
                     /translation="MTELEKQLLSALEQLQQDYSKRLDEWESAFGEWRKMSGLMQRENA
                     ALSERVTRLSQQVERLSGQLQRLSR"
                     /name="MbeD family mobilization/exclusion protein"
     gene            complement(3334..3462)
                     /locus_tag="C6M51_RS27765"
     CDS             complement(3334..3462)
                     /locus_tag="C6M51_RS27765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000523570.1"
                     /translation="MGLKPGPKRIADSTGEPDKRQRDNKKTPGNTDKLKPSKSSKK"
                     /name="hypothetical protein"
     gene            3625..3849
                     /locus_tag="C6M51_RS00300"
                     /old_locus_tag="C6M51_00330"
     CDS             3625..3849
                     /locus_tag="C6M51_RS00300"
                     /old_locus_tag="C6M51_00330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6290 family protein"
                     /protein_id="WP_000879771.1"
                     /translation="MLAIRLSDEIESRLDSLAKQTGRTKTFYAREAILAHLEDLEDYYL
                     SAETAARVRRGDEAVHSSEDVRKSLGLDD"
                     /name="DUF6290 family protein"
     gene            3833..4099
                     /locus_tag="C6M51_RS00305"
                     /old_locus_tag="C6M51_00325"
     CDS             3833..4099
                     /locus_tag="C6M51_RS00305"
                     /old_locus_tag="C6M51_00325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262326.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_004197762.1"
                     /translation="MVWTINYSDRALKSLRKMDKQNARRIVDFMSLRIAVAADPRQSGK
                     PLKGELGEFWRYRVGDYRVLCEIRDDELVILAATIGHRREVYD"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(4169..4519)
                     /locus_tag="C6M51_RS00310"
                     /old_locus_tag="C6M51_00320"
     CDS             complement(4169..4519)
                     /locus_tag="C6M51_RS00310"
                     /old_locus_tag="C6M51_00320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004197756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004197756.1"
                     /translation="MYWLIAFLAFIFPGRSFADGYTAYYRCNGTQEASLTVKDNKLSMV
                     VGLSKFNRQLDTYRFKEKGIEVVMQRAASDDNSEAIMSFIMPDVNNMTLLVKNNGYIIV
                     KTTCWLTKTDKQ"
                     /name="hypothetical protein"
     gene            complement(4585..5130)
                     /locus_tag="C6M51_RS00315"
                     /old_locus_tag="C6M51_00315"
     CDS             complement(4585..5130)
                     /locus_tag="C6M51_RS00315"
                     /old_locus_tag="C6M51_00315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004197758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_023317533.1"
                     /translation="MFFKRYLTEKEIYKAALPIVRLQGRVNTSLRFLSKYSDVNKNGLI
                     ALHLNLLHFISYNIHGVESLKITQAGINKAVQQSPHADEIKNIAQAIGRKGPEYIEGLI
                     RNPWGKKNDNPLIFIMSIEESIKETLNSGYMLYRVAPITEGEAAAFMDVLKQLLLFEDN
                     FRLFGRDLVYKIEKLKIR"
                     /name="hypothetical protein"
     gene            complement(5156..5482)
                     /locus_tag="C6M51_RS00320"
                     /old_locus_tag="C6M51_00310"
     CDS             complement(5156..5482)
                     /locus_tag="C6M51_RS00320"
                     /old_locus_tag="C6M51_00310"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_050516389.1"
                     /translation="MRERTNIMLDIGLKQSLQRLSNKTKMSLSDLINQRLSGSLSVEER
                     IGEKPEWMRNLDPYLANHFSNIELPLPSPLKEYQEKMDEIDSIINDMMVLKEYFRAKFY
                     DEIK"
                     /name="hypothetical protein"
     Typing          877..956
                     /name="MOBP"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="90.361"
                     /coverage="97.0"
                     /evalue="1.1100000000000001e-21"
     Typing          complement(294..691)
                     /name="rep_cluster_2370"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="89.526"
                     /coverage="91.0"
                     /evalue="3.03e-139"
     Typing          1543..3074
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="99.804"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 ggcatcagtg gcgggtgttt ttccgtggga tggatggagc tccggggata acagaactga
       61 cgatcattta aaggatcttc ttgagatcct ttttttctgc gcgtaatctc ttgcactgta
      121 aacgaaaaaa ccgcctgggg aggcggtttg atcgaaggtt aagtcagttg gggaactgct
      181 taaccgggta actgggtata cgagaccgca gataccaaaa ctgttctttc agtgtagccg
      241 cagttaggca cccacttcaa gacctctcaa tatctctctc gtatatatcc agttaccaat
      301 ggctgctgcc agtggcgttt ttgcgtgtcc gtccgggttg gactcaagat gatagttacc
      361 ggaaagggcg cagcagtcgg gctgaacggg gggttcgtgc atacagccca gcttggagcg
      421 aacgacctaa accgagccga gataccagca gcgtgagcta tgagaaagcg ccacgcttcc
      481 cgaaagggaa aaaggcggaa caggtatccg gtaaacggca gggtcggaac aggagagcgc
      541 acgagggagc cgccggagag aaatcaccgg catctttaag tcctgtcggg tttcgtcctc
      601 ctctgacttg agcgtccatt tctgtgatgc tcgtcagggg aggcggagcc tatggaaaaa
      661 cggcaacgcc gcatcctttt ctccggccct ttctgatttg agcgcctttg ctttatcccg
      721 ttatccgtga gtcggtcacg cccgccgcag ccgaacggca ggagcgcagc taccgagtga
      781 gcgaggaggc gtcatttcat ctgtccgtgc atggtattgc ggacgctcct gagccacata
      841 tcacacctgc cacatgaggc actttcatga atcgtgctct catgccaaca tagtaagcca
      901 gtatacacag cgtaaacgct gtgactggtt cagggctgcg ccccgaaacc cgctaacacc
      961 actgacgcgc tggcgcttgt ccaacgccgg agcgacccgg aaaacttttc cgtgccgtcc
     1021 ggcgtttgcg aaggagggat aatgcagaag ccgaagaaga agccgctcgt cgtaaaaaaa
     1081 agatcctggc atccggcagt gatggcaaat ctgatgcgtc aggcacagga ggaagattac
     1141 cgccgggagc agatggcaga gcttgagcgt tcagcccggt cacattttgc ggatatcgga
     1201 ggagaggatg gcggttaagc gtacccgttt tttaggtatc cgggtgaccg atggggagta
     1261 ccagcagctg ctggagcgct gcaatggaag gcaactggcg gtgtggatgc gggaaacctg
     1321 tctcgatacg cgcccggcgc ggtcgttgcg gctgccgtcc atcgatccgg ttttgctgcg
     1381 ccagcttgcc gggatgggga acaacctcaa ccagatcgcc cggaaaatta acggcggcca
     1441 gtggtcaggc gctgaccggg ttcaggtggt ggccgcgctg atggccattg atgccgaact
     1501 cgagcggctg cggcatgccg tgctggaaaa gggggcagac gatgatcgtt aagtttcatc
     1561 cgcgagggcg aggcggcggt gccgggccgg tggattatct gctggggaaa gaccgccagc
     1621 gcgacggggc catcgtcctg cagggaaagc cggaggaggt ccgggagctt atcgacgcct
     1681 cgccctacgc caaaaagtac acctccggcg tcctgtcttt tgctgaacag gatttaccgc
     1741 ccggccagcg tgaaaagctg atggcgagct tcgagcgggt tctgatgccc ggactcgata
     1801 aagaccagta cagcgtgctg tgggttgaac accgggacaa ggggcggctg gaactgaatt
     1861 ttctggtacc gaacacggaa ctgctgaccg gcaggcgtct ccagccgtac tacgaccggg
     1921 cagaccgtcc gcgcatcgat gcgtggcaga ccgtggtgaa cgggcgactg gggctgcacg
     1981 acccgaacgc accggagaac cggcgcgcgc tggtgacgcc atcttcgtta cccaaaacga
     2041 agcaggaagc cgcagaggct attacgcggg gcttactggc cctcgcctcg tcaggggagc
     2101 ttaaaacgcg tcaggacgtc actgaggcgc tggaaagcgc aggttttgag gtcgtgcgca
     2161 ccacaaagag cagcatcagc attgccgacc cggacggagg gcgaaacatc cgacttaagg
     2221 gagccatcta tgaacagtct tttaacgctg gcgaaggact tagagcagaa atcgaaagcg
     2281 cagcagcaga gtaccggcga aatgctgaaa gccgcattca gcgagcacga gaagtctgtc
     2341 agagcggaac tgagcgaaag cgggaagaga atcagcgccg ccatccgcgc ccacgagcag
     2401 ggtatgagcg cggccatgca gtcgaaccgc ctgagcgtga tgcgtatggt cgggcggaca
     2461 tggctgacca tcacgatggt gtcaggactg ctgttcgcca gcctgagcgg ggtgttgtgg
     2521 tatcagggga gcttgatagc gtcaaatctg gccgaaatcg accggcagaa cgcagcgctg
     2581 tcgaagctga acgcgaagac ctggggcgtg acgtacctgg aagacagcaa cggacgtttt
     2641 ctggtgctgc cgaaggggac ggccgtagac aggacgcaga gctggacggt cgggaacggg
     2701 cggtcgaagc agaacgcgct gagactggtg aaggagtaag tgccgatgac cgagctggaa
     2761 aaacagttgc tgagcgcatt agagcagcta cagcaggact actcgaaaag gctggacgag
     2821 tgggagagcg ccttcgggga atggcggaaa atgtcagggc ttatgcaacg ggagaacgcg
     2881 gcgctgagcg agcgcgtgac gcgcttgagt cagcaggtgg aacgcttgag cgggcaactg
     2941 cagcgtttga gccggtagtg cagcgtcatg agatggccgt ggccgcagaa cgggcgcacg
     3001 agcaacggca gcacgaaaag gaactgacgg aagcgcgttc ccggcagcga agctatgacg
     3061 gtccgtcgct gggctgaaat gcaggaaaac agggttctca tcgggcattt acgctgaaac
     3121 cggatgtcat tcacctggct gcatggctat gcagccaggt aaaatttatc tgtcgcgaac
     3181 ggggcggttt atcgggtggt ttgttgccgg ttttacctga ctgccacccc gttcgcggcg
     3241 aacccgtccg gggcggtgcg ggcaacgggt gttatgttta atcagcgtga acggcagata
     3301 caaaaaagcc ccggagggct tttaactact gacttatttt tttgaagatt tgctgggttt
     3361 caatttgtca gtatttcccg gcgttttttt attgtcacgc tggcgtttat caggttcccc
     3421 tgttgaatcg gcaattcgtt tcggacccgg cttaagaccc ataatcgtta tcctttcaat
     3481 agttaagagg aaagccctca agctagatat attgaccgcg ttacggatta tcaagagggg
     3541 ctaacaagat tattttttgt tcttttaggt tgattgtggt actgttgata tacatgtata
     3601 gcaaatggtg ttcgggaggt ttatatgctt gctatccggt tatctgatga gattgagtcc
     3661 cgtctggact cgctggcgaa gcaaaccggc agaacaaaga cgttttatgc gcgggaagca
     3721 atactggcgc atctggaaga cctggaggat tattatcttt cagcagaaac tgctgcacgc
     3781 gttcgccgtg gtgatgaagc agtgcattcg tctgaagacg tgaggaagtc acttggtctg
     3841 gacgattaac tattccgatc gggcgctcaa atcgttacgc aagatggaca aacagaacgc
     3901 acgacggatt gtggatttta tgagtttacg cattgcagtt gctgccgatc ctcgccagtc
     3961 agggaagccg ctcaaaggtg agctgggcga gttctggcgc tatcgggtgg gagattatcg
     4021 cgttctgtgt gagatccgag atgacgagct tgttatcctt gccgccacga ttggacatcg
     4081 ccgcgaagtt tacgactgaa gcccgctatg cgggcttttt tgatgccgac aacaggtatt
     4141 atggtaaata ctcgactaac tacgtgttct actgtttgtc ggttttagtt aaccagcagg
     4201 ttgtcttaac gataatgtag ccgttatttt taactaataa ggtcatattg ttaacgtcag
     4261 gcataataaa agacattatg gcctcagagt tatcatcaga agcagctctc tgcattacta
     4321 cttcgattcc cttttctttg aatctataag tatccagttg cctattaaac ttagaaagac
     4381 ctacaaccat acttagtttg ttatctttaa cagtaagaga tgcttcctga gtaccattac
     4441 atcggtagta agcggtgtaa ccgtcagcaa aagatcgacc ggggaatata aatgctagga
     4501 acgcaattaa ccaatacata gttgagaatc ttggtattac acatttcact atcctctctt
     4561 tcatttttcg ttcaccatac tttgttatct gatttttaat ttttctattt tataaaccaa
     4621 gtctctacca aaaaggcgaa aattatcctc aaataataat aattgtttaa gaacatccat
     4681 gaaagcagct gcttcaccct cagttatggg agctactcta tataacatat aacctgagtt
     4741 aagggtttct tttatacttt cttcaatgct cattataaat attagtggat tatcattttt
     4801 cttcccccat gggtttctaa ttaatccttc gatgtactca ggtcctttgc gtcctattgc
     4861 ctgcgcaata ttttttattt catctgcgtg agggctttgt tgtacagctt tgtttatgcc
     4921 tgcttgagtg attttcagag actctacacc gtgtatgttg tatgagataa aatgtaataa
     4981 attaagatgc aatgcaatta atccattttt gtttacatct gagtatttgg ataaaaaacg
     5041 taatgaagtg ttaactctcc cttgaagcct aacaattggg agtgctgcct tgtatatttc
     5101 cttctccgtt aaataccgtt taaaaaacat aattctccgc ctccgtatag cgtgcctatt
     5161 ttatttcgtc gtaaaactta gctctgaaat attcctttag aaccatcatg tcattaataa
     5221 ttgaatctat ctcatccatt ttttcttggt attcttttaa tggtgaaggg agcggtaact
     5281 caatatttga aaagtgattg gcgagatagg gatcaaggtt tctcatccat tcaggctttt
     5341 cgccaatgcg ttcttcaact gaaagtgaac ctgataatct ctggttaata agatcactta
     5401 gactcatttt ggttttattc gaaagccgtt gtaaggattg ctttaatcct atatctagca
     5461 tgatatttgt tctttctctc attacccccc cttgctattg cgttttttgt tgcgcacaaa
     5521 gctaccattg cgcattaaga aacgcaataa aaaaggaggg agggagtggt ttgtacatga
     5581 tgtgcagtgc gctgag
//
