LOCUS       NZ_CP028546             5596 bp    DNA     circular CON 09-JAN-2024
DEFINITION  Klebsiella pneumoniae subsp. pneumoniae strain SCKP020143 plasmid
            p4_020143, complete sequence.
ACCESSION   NZ_CP028546
VERSION     NZ_CP028546.2
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN07609091
            Assembly: GCF_002853435.3
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae subsp. pneumoniae
  ORGANISM  Klebsiella pneumoniae subsp. pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 5596)
  AUTHORS   Liu,L., Long,H., Feng,Y. and Zong,Z.
  TITLE     The complete genome of Klebsiella pneumoniae strain SCKP020143
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5596)
  AUTHORS   Liu,L., Long,H., Feng,Y. and Zong,Z.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-AUG-2019) Center of Infectious Diseases, West China
            Hospital, Sichuan University, Guoxuexiang 37, Chengdu, Sichuan
            610041, China
  REMARK    Sequence update by submitter
REFERENCE   3  (bases 1 to 5596)
  AUTHORS   Liu,L., Long,H., Feng,Y. and Zong,Z.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-APR-2018) Center of Infectious Diseases, West China
            Hospital, Sichuan University, Guoxuexiang 37, Chengdu, Sichuan
            610041, China
REFERENCE   4  (bases 1 to 5596)
  AUTHORS   Liu,L., Lu,Y., Lin,J., Yang,B., Feng,Y. and Zong,Z.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-SEP-2017) Center of Infectious Diseases, West China
            Hospital, Sichuan University, Guoxuexiang 37, Chengdu, Sichuan
            610041, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.4
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200.0x
            Sequencing Technology             :: Illumina HiSeq; MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/09/2024 02:42:28
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,831
            CDSs (total)                      :: 5,708
            Genes (coding)                    :: 5,563
            CDSs (with protein)               :: 5,563
            Genes (RNA)                       :: 123
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 87
            ncRNAs                            :: 11
            Pseudo Genes (total)              :: 145
            CDSs (without protein)            :: 145
            Pseudo Genes (ambiguous residues) :: 0 of 145
            Pseudo Genes (frameshifted)       :: 51 of 145
            Pseudo Genes (incomplete)         :: 95 of 145
            Pseudo Genes (internal stop)      :: 12 of 145
            Pseudo Genes (multiple problems)  :: 13 of 145
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP028546.2.
            On Aug 18, 2021 this sequence version replaced NZ_CP028546.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..5596
                     /organism="Klebsiella pneumoniae subsp. pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="SCKP020143"
                     /host="Homo sapiens"
                     /sub_species="pneumoniae"
                     /db_xref="taxon:72407"
                     /plasmid="p4_020143"
                     /geo_loc_name="China: Zigong, Sichuan"
                     /collection_date="2017"
     gene            complement(join(5501..5596,1..81))
                     /locus_tag="CLQ46_RS01480"
     CDS             complement(join(5501..5596,1..81))
                     /locus_tag="CLQ46_RS01480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004197757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004197757.1"
                     /translation="MQKPKKKPLVVKKRSWHPAVMANLMRQAQEEDYRREQMAELERSA
                     RSHFADIGGEDGG"
                     /name="hypothetical protein"
     gene            721..879
                     /locus_tag="CLQ46_RS29295"
     CDS             721..879
                     /locus_tag="CLQ46_RS29295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_071596352.1"
                     /translation="MHEPPVQPDCCALSGNYHLESNPDGHAKTPLAAAIGNWIYTREIL
                     RGLEVGA"
                     /name="replication initiation protein"
     gene            1237..1563
                     /locus_tag="CLQ46_RS01485"
                     /old_locus_tag="CLQ46_01640"
     CDS             1237..1563
                     /locus_tag="CLQ46_RS01485"
                     /old_locus_tag="CLQ46_01640"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_050516389.1"
                     /translation="MRERTNIMLDIGLKQSLQRLSNKTKMSLSDLINQRLSGSLSVEER
                     IGEKPEWMRNLDPYLANHFSNIELPLPSPLKEYQEKMDEIDSIINDMMVLKEYFRAKFY
                     DEIK"
                     /name="hypothetical protein"
     gene            1589..2134
                     /locus_tag="CLQ46_RS01490"
                     /old_locus_tag="CLQ46_01645"
     CDS             1589..2134
                     /locus_tag="CLQ46_RS01490"
                     /old_locus_tag="CLQ46_01645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004197758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_023317533.1"
                     /translation="MFFKRYLTEKEIYKAALPIVRLQGRVNTSLRFLSKYSDVNKNGLI
                     ALHLNLLHFISYNIHGVESLKITQAGINKAVQQSPHADEIKNIAQAIGRKGPEYIEGLI
                     RNPWGKKNDNPLIFIMSIEESIKETLNSGYMLYRVAPITEGEAAAFMDVLKQLLLFEDN
                     FRLFGRDLVYKIEKLKIR"
                     /name="hypothetical protein"
     gene            2200..2550
                     /locus_tag="CLQ46_RS01495"
                     /old_locus_tag="CLQ46_01650"
     CDS             2200..2550
                     /locus_tag="CLQ46_RS01495"
                     /old_locus_tag="CLQ46_01650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004197756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004197756.1"
                     /translation="MYWLIAFLAFIFPGRSFADGYTAYYRCNGTQEASLTVKDNKLSMV
                     VGLSKFNRQLDTYRFKEKGIEVVMQRAASDDNSEAIMSFIMPDVNNMTLLVKNNGYIIV
                     KTTCWLTKTDKQ"
                     /name="hypothetical protein"
     gene            complement(2620..2886)
                     /locus_tag="CLQ46_RS01500"
                     /old_locus_tag="CLQ46_01655"
     CDS             complement(2620..2886)
                     /locus_tag="CLQ46_RS01500"
                     /old_locus_tag="CLQ46_01655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262326.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_004197762.1"
                     /translation="MVWTINYSDRALKSLRKMDKQNARRIVDFMSLRIAVAADPRQSGK
                     PLKGELGEFWRYRVGDYRVLCEIRDDELVILAATIGHRREVYD"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(2870..3094)
                     /locus_tag="CLQ46_RS01505"
                     /old_locus_tag="CLQ46_01660"
     CDS             complement(2870..3094)
                     /locus_tag="CLQ46_RS01505"
                     /old_locus_tag="CLQ46_01660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6290 family protein"
                     /protein_id="WP_000879771.1"
                     /translation="MLAIRLSDEIESRLDSLAKQTGRTKTFYAREAILAHLEDLEDYYL
                     SAETAARVRRGDEAVHSSEDVRKSLGLDD"
                     /name="DUF6290 family protein"
     gene            3257..3385
                     /locus_tag="CLQ46_RS29215"
     CDS             3257..3385
                     /locus_tag="CLQ46_RS29215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000523570.1"
                     /translation="MGLKPGPKRIADSTGEPDKRQRDNKKTPGNTDKLKPSKSSKK"
                     /name="hypothetical protein"
     gene            complement(3761..3973)
                     /locus_tag="CLQ46_RS01510"
                     /old_locus_tag="CLQ46_01625"
     CDS             complement(3761..3973)
                     /locus_tag="CLQ46_RS01510"
                     /old_locus_tag="CLQ46_01625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeD family mobilization/exclusion protein"
                     /protein_id="WP_021527181.1"
                     /translation="MTELEKQLLSALEQLQQDYSKRLDEWESAFGEWRKMSGLMQRENA
                     ALSERVTRLSQQVERLSGQLQRLSR"
                     /name="MbeD family mobilization/exclusion protein"
     gene            complement(3980..4489)
                     /locus_tag="CLQ46_RS01515"
                     /old_locus_tag="CLQ46_30065"
     CDS             complement(3980..4489)
                     /locus_tag="CLQ46_RS01515"
                     /old_locus_tag="CLQ46_30065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020325392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeB family mobilization protein"
                     /protein_id="WP_032433972.1"
                     /translation="MNSLLTLAKDLEQKSKAQQQSTGEMLKAAFSEHEKSVRAELSESG
                     KRISAAIRAHEQGMSAAMQSNRLSVMRMVGRTWLTITMVSGLLFASLSGVLWYQGSLIA
                     SNLAEIDRQNAALSKLNAKTWGVTYLEDSNGRFLVLPKGTAVDRTQSWTVGNGRSKQNA
                     LRLVKE"
                     /name="MbeB family mobilization protein"
     gene            complement(<4524..5228)
                     /locus_tag="CLQ46_RS29300"
                     /old_locus_tag="CLQ46_30070"
                     /pseudo=""
     CDS             complement(<4524..5228)
                     /locus_tag="CLQ46_RS29300"
                     /old_locus_tag="CLQ46_30070"
                     /inference="COORDINATES: protein motif:HMM:NF015397.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /name="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            complement(5167..5511)
                     /locus_tag="CLQ46_RS01525"
                     /old_locus_tag="CLQ46_01630"
     CDS             complement(5167..5511)
                     /locus_tag="CLQ46_RS01525"
                     /old_locus_tag="CLQ46_01630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006122514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="WP_062955149.1"
                     /translation="MAVKRTRFLGIRVTDGEYQQLLERCNGRQLAVWMRETCLDTRPAR
                     SLRLPSIDPVLLRQLAGMGNNLNQIARKINGGQWSGADRVQVVAALMAIDAELERLRHA
                     VLEKGADDDR"
                     /name="MobC family plasmid mobilization relaxosome protein"
     Typing          complement(168..244)
                     /name="MOBP"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="91.25"
                     /coverage="98.0"
                     /evalue="1.04e-21"
     Typing          433..830
                     /name="rep_cluster_2370"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="89.526"
                     /coverage="91.0"
                     /evalue="3.03e-139"
     Typing          complement(3646..5177)
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="99.804"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 ctgacgcatc agatttgcca tcactgccgg atgccaggat ctttttttta cgacgagcgg
       61 cttcttcttc ggcttctgca ttatccctcc ttcgcaaacg ccggacggca cggaaaagtt
      121 ttccgggtcg ctccggcgtt ggacaagcgc cagcgcgtca gtggtgttag cgggtttcgg
      181 ggcgcagccc tgaaccagtc acagcgttta cgctgtgtat actggcttac tatgttggca
      241 tgagagcacg attcatgaaa gtgcctcatg tggcaggtgt gatatgtggc tcaggagcgt
      301 ccgcaatacc atgcacggac agatgaaatg acgcctcctc gctcactcgg tagctgcgct
      361 cctgccgttc ggctgcggcg ggcgtgaccg actcacggat aacgggataa agcaaaggcg
      421 ctcaaatcag aaagggccgg agaaaaggat gcggcgttgc cgtttttcca taggctccgc
      481 ctcccctgac gagcatcaca gaaatggacg ctcaagtcag aggaggacga aacccgacag
      541 gacttaaaga tgccggtgat ttctctccgg cggctccctc gtgcgctctc ctgttccgac
      601 cctgccgttt accggatacc tgttccgcct ttttcccttt cgggaagcgt ggcgctttct
      661 catagctcac gctgctggta tctcggctcg gtttaggtcg ttcgctccaa gctgggctgt
      721 atgcacgaac cccccgttca gcccgactgc tgcgcccttt ccggtaacta tcatcttgag
      781 tccaacccgg acggacacgc aaaaacgcca ctggcagcag ccattggtaa ctggatatat
      841 acgagagaga tattgagagg tcttgaagtg ggtgcctaac tgcggctaca ctgaaagaac
      901 agttttggta tctgcggtct cgtataccca gttacccggt taagcagttc cccaactgac
      961 ttaaccttcg atcaaaccgc ctccccaggc ggttttttcg tttacagtgc aagagattac
     1021 gcgcagaaaa aaaggatctc aagaagatcc tttaaatgat cgtcagttct gttatccccg
     1081 gagctccatc catcccacgg aaaaacaccc gccactgatg ccctcagcgc actgcacatc
     1141 atgtacaaac cactccctcc ctcctttttt attgcgtttc ttaatgcgca atggtagctt
     1201 tgtgcgcaac aaaaaacgca atagcaaggg ggggtaatga gagaaagaac aaatatcatg
     1261 ctagatatag gattaaagca atccttacaa cggctttcga ataaaaccaa aatgagtcta
     1321 agtgatctta ttaaccagag attatcaggt tcactttcag ttgaagaacg cattggcgaa
     1381 aagcctgaat ggatgagaaa ccttgatccc tatctcgcca atcacttttc aaatattgag
     1441 ttaccgctcc cttcaccatt aaaagaatac caagaaaaaa tggatgagat agattcaatt
     1501 attaatgaca tgatggttct aaaggaatat ttcagagcta agttttacga cgaaataaaa
     1561 taggcacgct atacggaggc ggagaattat gttttttaaa cggtatttaa cggagaagga
     1621 aatatacaag gcagcactcc caattgttag gcttcaaggg agagttaaca cttcattacg
     1681 ttttttatcc aaatactcag atgtaaacaa aaatggatta attgcattgc atcttaattt
     1741 attacatttt atctcataca acatacacgg tgtagagtct ctgaaaatca ctcaagcagg
     1801 cataaacaaa gctgtacaac aaagccctca cgcagatgaa ataaaaaata ttgcgcaggc
     1861 aataggacgc aaaggacctg agtacatcga aggattaatt agaaacccat gggggaagaa
     1921 aaatgataat ccactaatat ttataatgag cattgaagaa agtataaaag aaacccttaa
     1981 ctcaggttat atgttatata gagtagctcc cataactgag ggtgaagcag ctgctttcat
     2041 ggatgttctt aaacaattat tattatttga ggataatttt cgcctttttg gtagagactt
     2101 ggtttataaa atagaaaaat taaaaatcag ataacaaagt atggtgaacg aaaaatgaaa
     2161 gagaggatag tgaaatgtgt aataccaaga ttctcaacta tgtattggtt aattgcgttc
     2221 ctagcattta tattccccgg tcgatctttt gctgacggtt acaccgctta ctaccgatgt
     2281 aatggtactc aggaagcatc tcttactgtt aaagataaca aactaagtat ggttgtaggt
     2341 ctttctaagt ttaataggca actggatact tatagattca aagaaaaggg aatcgaagta
     2401 gtaatgcaga gagctgcttc tgatgataac tctgaggcca taatgtcttt tattatgcct
     2461 gacgttaaca atatgacctt attagttaaa aataacggct acattatcgt taagacaacc
     2521 tgctggttaa ctaaaaccga caaacagtag aacacgtagt tagtcgagta tttaccataa
     2581 tacctgttgt cggcatcaaa aaagcccgca tagcgggctt cagtcgtaaa cttcgcggcg
     2641 atgtccaatc gtggcggcaa ggataacaag ctcgtcatct cggatctcac acagaacgcg
     2701 ataatctccc acccgatagc gccagaactc gcccagctca cctttgagcg gcttccctga
     2761 ctggcgagga tcggcagcaa ctgcaatgcg taaactcata aaatccacaa tccgtcgtgc
     2821 gttctgtttg tccatcttgc gtaacgattt gagcgcccga tcggaatagt taatcgtcca
     2881 gaccaagtga cttcctcacg tcttcagacg aatgcactgc ttcatcacca cggcgaacgc
     2941 gtgcagcagt ttctgctgaa agataataat cctccaggtc ttccagatgc gccagtattg
     3001 cttcccgcgc ataaaacgtc tttgttctgc cggtttgctt cgccagcgag tccagacggg
     3061 actcaatctc atcagataac cggatagcaa gcatataaac ctcccgaaca ccatttgcta
     3121 tacatgtata tcaacagtac cacaatcaac ctaaaagaac aaaaaataat cttgttagcc
     3181 cctcttgata atccgtaacg cggtcaatat atctagcttg agggctttcc tcttaactat
     3241 tgaaaggata acgattatgg gtcttaagcc gggtccgaaa cgaattgccg attcaacagg
     3301 ggaacctgat aaacgccagc gtgacaataa aaaaacgccg ggaaatactg acaaattgaa
     3361 acccagcaaa tcttcaaaaa aataagtcag tagttaaaag ccctccgggg cttttttgta
     3421 tctgccgttc acgctgatta aacataacac ccgttgcccg caccgccccg gacgggttcg
     3481 ccgcgaacgg ggtggcagtc aggtaaaacc ggcaacaaac cacccgataa accgccccgt
     3541 tcgcgacaga taaattttac ctggctgcat agccatgcag ccaggtgaat gacatccggt
     3601 ttcagcgtaa atgcccgatg agaaccctgt tttcctgcat ttcagcccag cgacggaccg
     3661 tcatagcttc gctgccggga acgcgcttcc gtcagttcct tttcgtgctg ccgttgctcg
     3721 tgcgcccgtt ctgcggccac ggccatctca tgacgctgca ctaccggctc aaacgctgca
     3781 gttgcccgct caagcgttcc acctgctgac tcaagcgcgt cacgcgctcg ctcagcgccg
     3841 cgttctcccg ttgcataagc cctgacattt tccgccattc cccgaaggcg ctctcccact
     3901 cgtccagcct tttcgagtag tcctgctgta gctgctctaa tgcgctcagc aactgttttt
     3961 ccagctcggt catcggcact tactccttca ccagtctcag cgcgttctgc ttcgaccgcc
     4021 cgttcccgac cgtccagctc tgcgtcctgt ctacggccgt ccccttcggc agcaccagaa
     4081 aacgtccgtt gctgtcttcc aggtacgtca cgccccaggt cttcgcgttc agcttcgaca
     4141 gcgctgcgtt ctgccggtcg atttcggcca gatttgacgc tatcaagctc ccctgatacc
     4201 acaacacccc gctcaggctg gcgaacagca gtcctgacac catcgtgatg gtcagccatg
     4261 tccgcccgac catacgcatc acgctcaggc ggttcgactg catggccgcg ctcataccct
     4321 gctcgtgggc gcggatggcg gcgctgattc tcttcccgct ttcgctcagt tccgctctga
     4381 cagacttctc gtgctcgctg aatgcggctt tcagcatttc gccggtactc tgctgctgcg
     4441 ctttcgattt ctgctctaag tccttcgcca gcgttaaaag actgttcata gatggctccc
     4501 ttaagtcgga tgtttcgccc tccgtccggg tcggcaatgc tgatgctgct ctttgtggtg
     4561 cgcacgacct caaaacctgc gctttccagc gcctcagtga cgtcctgacg cgttttaagc
     4621 tcccctgacg aggcgagggc cagtaagccc cgcgtaatag cctctgcggc ttcctgcttc
     4681 gttttgggta acgaagatgg cgtcaccagc gcgcgccggt tctccggtgc gttcgggtcg
     4741 tgcagcccca gtcgcccgtt caccacggtc tgccacgcat cgatgcgcgg acggtctgcc
     4801 cggtcgtagt acggctggag acgcctgccg gtcagcagtt ccgtgttcgg taccagaaaa
     4861 ttcagttcca gccgcccctt gtcccggtgt tcaacccaca gcacgctgta ctggtcttta
     4921 tcgagtccgg gcatcagaac ccgctcgaag ctcgccatca gcttttcacg ctggccgggc
     4981 ggtaaatcct gttcagcaaa agacaggacg ccggaggtgt actttttggc gtagggcgag
     5041 gcgtcgataa gctcccggac ctcctccggc tttccctgca ggacgatggc cccgtcgcgc
     5101 tggcggtctt tccccagcag ataatccacc ggcccggcac cgccgcctcg ccctcgcgga
     5161 tgaaacttaa cgatcatcgt ctgccccctt ttccagcacg gcatgccgca gccgctcgag
     5221 ttcggcatca atggccatca gcgcggccac cacctgaacc cggtcagcgc ctgaccactg
     5281 gccgccgtta attttccggg cgatctggtt gaggttgttc cccatcccgg caagctggcg
     5341 cagcaaaacc ggatcgatgg acggcagccg caacgaccgc gccgggcgcg tatcgagaca
     5401 ggtttcccgc atccacaccg ccagttgcct tccattgcag cgctccagca gctgctggta
     5461 ctccccatcg gtcacccgga tacctaaaaa acgggtacgc ttaaccgcca tcctctcctc
     5521 cgatatccgc aaaatgtgac cgggctgaac gctcaagctc tgccatctgc tcccggcggt
     5581 aatcttcctc ctgtgc
//
