LOCUS       NZ_CP027416             7927 bp    DNA     linear   CON 09-DEC-2023
DEFINITION  Salmonella enterica subsp. enterica serovar Typhimurium strain
            FDAARGOS_320 plasmid unnamed3.
ACCESSION   NZ_CP027416
VERSION     NZ_CP027416.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN06173333
            Assembly: GCF_002983965.1
KEYWORDS    RefSeq.
SOURCE      Salmonella enterica subsp. enterica serovar Typhimurium (Salmonella
            typhimurium)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhimurium
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 7927)
  AUTHORS   Zhao,S., McDermott,P., Tallon,L.J., Sadzewicz,L., Sengamalay,N.,
            Ott,S., Godinez,A., Nagaraj,S., Vavikolanu,K., Vyas,G., Nadendla,S.
            and Sichtig,H.
  TITLE     FDA dAtabase for Regulatory Grade micrObial Sequences (FDA-ARGOS):
            Supporting development and validation of Infectious Disease Dx tests
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7927)
  AUTHORS   Zhao,S., McDermott,P., Tallon,L.J., Sadzewicz,L., Sengamalay,N.,
            Ott,S., Godinez,A., Nagaraj,S., Vavikolanu,K., Vyas,G., Nadendla,S.
            and Sichtig,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-MAR-2018) Center for Devices and Radiological Health,
            US Food and Drug Administration, 10903 New Hampshire Avenue, Silver
            Spring, MD 20993-0002, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SMRT v. 2.3.0, HGAP v. 3.0
            Genome Coverage                   :: 12.7457354992732x
            Sequencing Technology             :: PacBio; Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 12/09/2023 09:46:14
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,928
            CDSs (total)                      :: 4,805
            Genes (coding)                    :: 4,661
            CDSs (with protein)               :: 4,661
            Genes (RNA)                       :: 123
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 15
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 71 of 144
            Pseudo Genes (incomplete)         :: 86 of 144
            Pseudo Genes (internal stop)      :: 29 of 144
            Pseudo Genes (multiple problems)  :: 38 of 144
            Pseudo Genes (short protein)      :: 1 of 144
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP027416.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..7927
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhimurium"
                     /mol_type="genomic DNA"
                     /strain="FDAARGOS_320"
                     /serovar="Typhimurium"
                     /isolation_source="Stool"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /culture_collection="FDA:FDAARGOS_320"
                     /db_xref="taxon:90371"
                     /plasmid="unnamed3"
                     /collection_date="2012"
                     /collected_by="FDA CVM < CDC"
     gene            <1..817
                     /gene="pilV"
                     /locus_tag="CEP98_RS26000"
                     /old_locus_tag="CEP98_25990"
                     /pseudo=""
     CDS             <1..817
                     /gene="pilV"
                     /locus_tag="CEP98_RS26000"
                     /old_locus_tag="CEP98_25990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527449.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=3
                     /transl_table=11
                     /product="shufflon system plasmid conjugative transfer
                     pilus tip adhesin PilV"
                     /name="pilV"
     gene            complement(1381..>1566)
                     /locus_tag="CEP98_RS26780"
                     /old_locus_tag="CEP98_26000"
                     /pseudo=""
     CDS             complement(1381..>1566)
                     /locus_tag="CEP98_RS26780"
                     /old_locus_tag="CEP98_26000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012565250.1"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            1680..2796
                     /locus_tag="CEP98_RS26785"
                     /old_locus_tag="CEP98_26005"
                     /pseudo=""
     CDS             1680..2796
                     /locus_tag="CEP98_RS26785"
                     /old_locus_tag="CEP98_26005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001396170.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA];
                     GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /name="site-specific integrase"
     gene            2944..3765
                     /gene="traE"
                     /locus_tag="CEP98_RS26020"
                     /old_locus_tag="CEP98_26010"
                     /pseudo=""
     CDS             2944..3765
                     /gene="traE"
                     /locus_tag="CEP98_RS26020"
                     /old_locus_tag="CEP98_26010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001238927.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /name="traE"
     gene            3850..5042
                     /gene="traF"
                     /locus_tag="CEP98_RS26025"
                     /old_locus_tag="CEP98_26015"
                     /pseudo=""
     CDS             3850..5042
                     /gene="traF"
                     /locus_tag="CEP98_RS26025"
                     /old_locus_tag="CEP98_26015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003557916.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraF"
                     /name="traF"
     gene            5101..5685
                     /locus_tag="CEP98_RS26030"
                     /old_locus_tag="CEP98_26020"
     CDS             5101..5685
                     /locus_tag="CEP98_RS26030"
                     /old_locus_tag="CEP98_26020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001542524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="WP_000977522.1"
                     /translation="MMKPRSSYSKTAFILLFSVFLVAAVTKAKSSLPDITLEQAKEINA
                     DNTVIFLFRHGERCDRSDMPCYSDKSGITITGTEKAQQEGIKFATIFSEYDIYSSNAVR
                     TIQTAKFFSGKEPVVMDSLSDCNNDLYKTLESIARESHKRNIVIMTHNHCLSFLARDRL
                     GKKFKPAYLDALIMHYDGTRLILDGKYNKEA"
                     /name="histidine phosphatase family protein"
     gene            6080..6538
                     /gene="traH"
                     /locus_tag="CEP98_RS26035"
                     /old_locus_tag="CEP98_26025"
     CDS             6080..6538
                     /gene="traH"
                     /locus_tag="CEP98_RS26035"
                     /old_locus_tag="CEP98_26025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IncI1-type conjugal transfer lipoprotein TraH"
                     /protein_id="WP_001079808.1"
                     /translation="MNRIIPAGCLAALFLAGCNSPSQHTPVPRNYGAASDVAVTRHTQY
                     TLWDKGVFSGQLPVSTGSHLLTANSDRLSFDWEGDAIELLNELARVRGMQFNYNGVRLP
                     LPVNLHVRDMTFSNTLRLIEAQTAWRATIHQYPGLLQVSFMQPENRKK"
                     /name="traH"
     gene            6535..7353
                     /gene="traI"
                     /locus_tag="CEP98_RS26040"
                     /old_locus_tag="CEP98_26030"
     CDS             6535..7353
                     /gene="traI"
                     /locus_tag="CEP98_RS26040"
                     /old_locus_tag="CEP98_26030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000646098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IncI1-type conjugal transfer lipoprotein TraI"
                     /protein_id="WP_000646098.1"
                     /translation="MKALTSLLLPVILLTGCSSSPTISPGGVNTPPPDINAWLKPRSEK
                     PDSLSETRWKMLTDAGKTLGFRGGKAQRSWELIQALNARESTLNALYDFRPLISPEGWL
                     PPVIDEAQDVAHITPDQIRTSSRVWTIIRPERFVSNPPGWRDWLLRGLSTTATPGTEGS
                     VVPEDSVQRKVWETALRQGWQEGRQNADLTLEANQKTLTRDYRGMMLYSLLWRQGMITR
                     PDVSDQMQTVTGDGKKLVTGDRVRRLKNHAEFNLQKSHWRPLIGTEGGSR"
                     /name="traI"
     gene            7350..>7927
                     /locus_tag="CEP98_RS26045"
                     /old_locus_tag="CEP98_26035"
                     /pseudo=""
     CDS             7350..>7927
                     /locus_tag="CEP98_RS26045"
                     /old_locus_tag="CEP98_26035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001480051.1"
                     /note="incomplete; too short partial abutting assembly gap;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid transfer ATPase TraJ"
                     /name="plasmid transfer ATPase TraJ"
     Typing          6536..7350
                     /name="MPF_I"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.632"
                     /coverage="100.0"
                     /evalue="4.87e-178"
ORIGIN
        1 gtaacgggca tattgccgta ttgttatcga cagatgaact tagtggtgca gctgaggaca
       61 ctgatcgtct ttacagattc caggtcaatg gtcgccctga cttaaacaaa atgcacacgg
      121 ccattgatat gggatcaaat aacctgaata acgttggggc agtaaatgcc cagacaggta
      181 atttcagcgg caatgtgaat ggtgtaaatg gcactttcag cggtcaggta aaaggcaata
      241 gcggaaactt tgacgtaaat gtcaccgctg gcgggatatc agaagtaata atggttggtt
      301 aattactcgt aacagtaaag gctggctcaa tgaaactcac ggtggcggat tttatatgtc
      361 cgatggatca tgggttcgaa gtgtaaacaa caagggcatc tataccggcg gtcaggtgaa
      421 aggcggtact gttcgggctg atggtcgcct ttatactggt gaatacttac aactggaaag
      481 aactgccgtt gctggcgcat catgttcgcc taacggcctt gtaggccgcg ataatacagg
      541 ggcaatactt tcgtgccaat ccggtacctg gagaaaggta ggatctggtg agcttcaaat
      601 tgctacagca caggccacag gttggcgctt tcctggagca acagctactt gtccaactgg
      661 aaaacgtgtt acaggtggcg gcggaatatg cacctcacga actggttaca tatggcttac
      721 caggtcattc ccatcagcca ataactcatg gtcggctgcg tgcgatacaa ccgaagatca
      781 gaatggttca ataactgtat atgccatttg ccaataagct atttcaagca agtaatcttc
      841 ataaagtagg acgaatactg tgtgtagttt ttggcttgcc aagtcatctc gccgttagag
      901 tcaggcatgt caataggaac gacttctgtt tctgccattt cacgcccgtc aatacgatag
      961 gtgttaatac acagtttaaa cctccctaag acctgtgtgt ttttgggata taacgtaaat
     1021 gtttttatat tcgtccatat cgacgctgat gatgatttcc aggtaccgga ttggcacgta
     1081 ggccagtgcc aatccggtac gtggaagact tctgggtcgc tcaatggttc cttacaccac
     1141 ttaggttcac ataggaggtt cattctaggg ccggaatcag gggcagtaca ttgtttatta
     1201 tgcatctgga ggtaatgaga tcgccggagg tcatgtgcaa atacatccga ctgcagggat
     1261 atgtttggtg ggacgctaat tagctgaatg cagcaaaacc cgatatggaa aaacagcctt
     1321 atcactttgc tgtacctgag gtacttccta tcagataaca tcctatccac agaaaataca
     1381 tcatgtggtg ccgggtattt tcagtattgg atatccaaac ttaatgagcg tacacacacg
     1441 caatacacct gtcttatgcc gtattgtacc atttgcgtga acctgctggg ctctcaacta
     1501 cctggcagta gtgggcatcc tctgcttgcc cattctggca atggcacaga agtcgaattg
     1561 ccccaataac ctgtggtgga aagctggtaa cttgagtttc cacctatttc ccccacgtac
     1621 cggattggca cgcttgcaga gaatgattgt tgcattattt ttgcctcttt tgaggttgca
     1681 tgccgtctcc acgcatccgt aaaatgtcct gtcacgcgca ctggataagt acctgaaaac
     1741 agtttctgtc acaagaaagg catcaacagg agttttaccg gagcaatgtt atcaagcgat
     1801 atcccattgc ccttcggaga tgacgaataa caaccgtgat attgctacat acagagacgt
     1861 tcgttagcag aaatcaaccc ccgaacgggt aaacccatta caggtattac tgtacgtctt
     1921 gaactcgcct tctgtcatct ctgttcatat tgctcgtgtt gaatggggaa cctgtcgtac
     1981 taacccggtt gaactggttc gcagccgaaa gtatctccgg acgagatcgc cggctaacgt
     2041 cttcagaaga acgtcgcctt tccgctattc cgcgaaaaat ctgatgttga tgtcatttcc
     2101 atcttgcctt gagacagcca tgcggcaggg cgaaatactg gccttacgtt gggagcacat
     2161 tgatttgcgc acgtgtggct catttacctg aaacaaacgg tcactcacgg gatgttcctc
     2221 tgtccagacg tgcccgtaac tttcttcaga tgatgccgtt aatctccacg gcaatgtttt
     2281 gttacaccgc atccggcttt aaatgcctgg aatagccaca caacgacttc gcatcgagga
     2341 cctgctttca cgatctacgg catgaagcat aagccgcttc ttcgaactgg gtagcctgaa
     2401 tgtaatggag attgctgcaa tatcaggaca tcgttccatg aatatgctga aacggtatac
     2461 tcatcttcgt gcatggcaac tggtcagtaa acttgatgcc cgccggcgca gacacaaaaa
     2521 gtggcagcat ggtttgtgcc gtatcctgcc catatcacga ccatcaatga agaaaatggc
     2581 agaaagcgca tcgtattgag atcggtgatt tgataacctt cacgtcactg ccacaacgaa
     2641 agaggaagca gttcaccgcg ccagtgaggt ttgttgcgta cactggccat tgcagcacag
     2701 aaaggcgaac gtgtcccatc tcccggagcg ttacctgtta acgaccctga ctacattatg
     2761 atttgccctc tgaacccggg cagcaccccg ctgtaaacat cattcaaaac acatacagaa
     2821 aggcgagtgc aacaactcgc caaacacatt cgatctgcat gatcgaatta ttcgtttcac
     2881 cagaaaaaca ccgaagatac aataaccaca tgagctgaaa agactttttc agtcggagga
     2941 acaatgagac tgaatacgac cggtattgcg gcccgaatga tgctctcgct ggacaaaaaa
     3001 gcaatcggcg aaaactcatc aacggtcgtc agataaaccc gacacctctg caggtccgtt
     3061 acccccaagg ggtaagagaa gttctgggga taatgagcga acaattagcc atatccaccg
     3121 ctgatttaac ccgaatcctg cttgaggatg ctcttcataa tatgtttatg cctgcggata
     3181 acaccgcagg gaacataata agcagaattg aatacatcat gctgtcgcat gatataaatg
     3241 cgccattact ggcaacattg ctgtcgccat ggaatatccg ctccacggtt atacaggacc
     3301 cggccagact tgcagactat ctttcagctg acgctctcga acatcttgct gaatgtttta
     3361 atctcaatcc ggactggctg aatggccatg aaaactatcc gatagcgttg tccggtgaat
     3421 ggccagatac tgctgataat ttcagaatgc ttattagtga tagcagcaac actgaagtta
     3481 ttttctggca tagtttcccc ttcgcaggaa atacgaaaag agaatattgc ggggtaatat
     3541 tgagacagaa aaaagaaata aatggctctg taatatccgg cactatcatt atcaccaaca
     3601 cttctgaacg atgaaaaaag aaaatggtta actgaatata caaccaggca gaatacaaca
     3661 atgtctttgc gacgcgtcac gttgagacct ggccttgccg ggaaccttat tacagggcaa
     3721 atactacctg ttagcttatt taatacgtct ttattaccct ggtaaatacc agatagtacc
     3781 aaagtaaaaa ttacggcaca tccgtgtcat agcgttgttt tgtctaaatt ctgataaaca
     3841 ggaaattaaa tgatgaagaa aaatcatatt acccgcacca tcattgcatc tgctgtatta
     3901 ttttccttta acgctgcagc agcgacgtca tattttgaag cgcgtaacga tgcaatgggt
     3961 ggtaccgggg tagcatcttc ccattatggt gtggcacctc tggcaaaccc ggctttactg
     4021 acaaagcaca acagcaatga tgatttcagc cttcttctgc cgtctgttgg ggcacaagtt
     4081 gctgatcctg atgatgtatc aaataaagct gatgatgtta aagatgactg ggatttgttt
     4141 gacagtgctg tagataacca gcatggcgta caacaggcag cgggcaatct taaacatcgt
     4201 ctgcaggaat tccgcaatat caatgcagat gctcaggtag gtgtatcagc tgtagcagcc
     4261 atggcaaatg acactctgcc gtttgccctt atggtcaagt cttacggaac tgtcagcgta
     4321 aacggaaaag taaacgatgc agacctggat tatctggaca aagttgccaa tggaacaatt
     4381 accgacgtcg ataagatgcc ctgacctcac gcgcattcgg gcgtgcagct gtaattaccg
     4441 acgtcggaat ttcattgcca agaactggaa acggcggaca aaaatggtct cttggcgtca
     4501 caccaaatat cagcgtgtgg acctgtttaa ctacaacgta acggttcgtg attacgacaa
     4561 agacgatttt tgacggtgac aagtaccaca acacgaaacg gattcaacgc cgatattggt
     4621 gctatacaga cctgaatgac aactggactg tcggtcttgt tgcccagaca tcattccacg
     4681 cagtatgata ctaaatcgtc aatggcttta aagaaacctt caaagttcgt ccgcaggcaa
     4741 ccgccggtgt atcctggcat aatgacctgt ttaccactgc tctggacatt gatctgactc
     4801 ctgccagtgg cttcacttct gacagcaaac gtcagtttgc aagtgttggt gctgaattta
     4861 acgcatggaa atgggcgcaa ttgcgtgccg gttatcgtca gaacatggca tcaaactccg
     4921 gaagcgcctt caccgctggc gttggtatct ctccatttga cgtcgtacat atcgatgttt
     4981 ccggcctggt aggaactgac cacgattacg gtgcaatggc acaacttcag ttcactttct
     5041 gattactgtc cccgcccccg gcactaaacc cgggggtatt ttatattcag tttaaataac
     5101 atgatgaaac cacgttcttc ttattcaaaa acagcattca ttcttttatt ttctgttttc
     5161 ctggtagcgg cagtgacaaa agcaaaaagc tcgcttcccg atatcaccct ggaacaggca
     5221 aaagaaatta atgctgataa caccgttatt ttccttttcc gccatggaga acgttgcgac
     5281 cgttcagata tgccatgcta ttcggataaa agcggaatca ctattaccgg tacagagaaa
     5341 gcacagcagg aaggtattaa gttcgcaaca atcttcagtg aatatgatat ttactccagc
     5401 aatgcggtaa gaaccataca aactgcaaaa ttcttctccg gtaaagaacc cgtcgttatg
     5461 gacagtttat cagactgcaa taatgatctt tataagacgc ttgaatcaat cgcaagagaa
     5521 tctcataaaa ggaacatagt aataatgaca cataatcatt gtttatcatt tctggccaga
     5581 gataggctcg gcaagaaatt caaaccggcg taccttgatg ccctgatcat gcattacgat
     5641 ggtacccggc tcatacttga cggaaaatac aacaaagagg catagaggat atttgaattt
     5701 acataaattc tgatatactc agtaagatac aagagtgtac gggcacatgt gcctgtctga
     5761 attgcaggtt atccggacga gggccgggaa ctgtttcagg gacaagcgcc ggtacgttcg
     5821 attcataaat cgtcgagtca tccatcatgg atcgattcgg cgcggagcgt taaagattac
     5881 gctcatattc gttttatgtc tgacgacaca tcaaccagcc agtatcagga ataatcacct
     5941 tcagtaaact atgaggctat ttacctggcc acactggcat ttatttccgg taacgcaagt
     6001 atagccggaa acaaacatca tcctgtctgt accggagcac cggtatatcc cattctgatt
     6061 taactgctca ggaattatta tgaaccgtat tatacctgcg gggtgtcttg ccgccctttt
     6121 tctggctggc tgcaactccc cttctcagca tactcctgtt ccgcgtaact acggtgctgc
     6181 ctctgatgtg gcggttaccc ggcacactca gtacacatta tgggacaaag gtgtattttc
     6241 cggccaactt ccggtttcaa cggggtctca tcttctgaca gctaacagcg atcgcctttc
     6301 ctttgactgg gaaggtgatg caattgaatt actgaacgaa ctggccagag tcagggggat
     6361 gcagtttaac tacaatggtg tccgcctgcc gttaccagtc aaccttcacg tccgggatat
     6421 gacgttttcc aatacgttga gacttattga agcccagaca gcctggagag caacaatcca
     6481 tcaatatccg ggcttgttac aggtcagctt catgcagccg gagaaccgga aaaaatgaaa
     6541 gcactcacct ctctcctttt gccagtaata ctgcttactg gttgttcttc ttcccctacc
     6601 atctcgccag gtggtgtcaa tacgccacca cctgacatta atgcatggct taaaccacga
     6661 agtgaaaagc cggatagtct gtcagaaaca cgctggaaaa tgctgacaga cgcaggtaaa
     6721 acgcttggat ttcgtggtgg caaggctcag cgttcatggg agctgattca ggcgctcaac
     6781 gcccgggaaa gcacacttaa tgccttatac gatttccggc cactgattag cccggaaggc
     6841 tggctaccac cggttattga tgaagcacag gacgtagctc atatcacgcc agatcaaatc
     6901 cggacctctt cccgggtctg gaccatcatt cgccctgaac gctttgtcag caatccaccg
     6961 ggctggcgtg actggcttct ccgggggctt tcaacaacag ccactccggg tacagaaggc
     7021 agcgtcgttc cagaagacag cgtgcaacga aaagtgtggg aaaccgcatt acggcaggga
     7081 tggcaggaag gaagacaaaa cgccgacctg acgcttgaag ccaaccagaa aaccctcacc
     7141 cgtgattacc ggggcatgat gctgtactca cttctctggc gtcagggcat gatcacccgt
     7201 ccggatgttt ctgatcaaat gcaaaccgtt acaggtgacg ggaaaaaact ggtcactgga
     7261 gatcgtgttc gtcgccttaa aaatcatgcg gaattcaatc ttcagaaatc tcactggcgt
     7321 ccgcttatag gcactgaagg aggctcccga tgaatattcc tgatgagttt ggtctttttc
     7381 cgtttcagcg tttcacggca gatgaactac ggcatttctt tgtctggtgt gccgcacata
     7441 aagtcagtga tgtggatctg accggcgggt cacctgtatc tgtcagtcgc tttggccgac
     7501 gggtgcgttg ttccagtgca acgttaccaa ccacactcat gtcctccctg attgatgaac
     7561 tgttcggtcg ggaagtcatt ccccgcgttc tggcaggcaa tccggttgac aggacgatac
     7621 agattaacgg ggatgcatcc ggtcgctatg gtcttaaacg cggagaacgc atccggttac
     7681 gctctcacct cattcagggc acatctggtg cggaggagaa agcaatatca ataaccatgc
     7741 gtgtcatccc gacagaaata ccggacatcc tctccatgaa cattgaacca gacctgcttg
     7801 aagcaatggt ctgcaaaagc ggtctgggat ttgtatgtgg tgaaaccggg tcagggaaat
     7861 caacgctgtg ttcagcactg taccgttaca ttatggacaa tttccccgac gccaaaatcg
     7921 tgacata
//
