LOCUS       NZ_CP027151             6451 bp    DNA     linear   CON 25-NOV-2023
DEFINITION  Klebsiella pneumoniae strain AR_0363 plasmid unnamed10.
ACCESSION   NZ_CP027151
VERSION     NZ_CP027151.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN07291506
            Assembly: GCF_002968475.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 6451)
  AUTHORS   Benahmed,F.H., Lutgring,J.D., Yoo,B., Machado,M., Brown,A.,
            McAllister,G., Perry,A., Halpin,A.L., Vavikolanu,K., Ott,S.,
            Zhao,X., Tallon,L.J., Sadzewicz,L., Aluvathingal,J., Nadendla,S.,
            Voskania-kordi,A., Simonyan,V., Patel,J. and Shawar,R.M.
  TITLE     FDA/CDC Antimicrobial Resistant Isolate Bank Genome Sequencing
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6451)
  AUTHORS   Benahmed,F.H., Lutgring,J.D., Yoo,B., Machado,M., Brown,A.,
            McAllister,G., Perry,A., Halpin,A.L., Vavikolanu,K., Ott,S.,
            Zhao,X., Tallon,L.J., Sadzewicz,L., Aluvathingal,J., Nadendla,S.,
            Voskania-kordi,A., Simonyan,V., Patel,J. and Shawar,R.M.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-FEB-2018) Center for Devices and Radiological Health,
            US Food and Drug Administration, 10903 New Hampshire Avenue, Silver
            Sring, MD 20993-0002, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SMRT v. 2.3.0; HGAP v. 3.0
            Genome Coverage                   :: 16.41x
            Sequencing Technology             :: Pacbio; Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/25/2023 04:23:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,878
            CDSs (total)                      :: 5,754
            Genes (coding)                    :: 5,603
            CDSs (with protein)               :: 5,603
            Genes (RNA)                       :: 124
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 88
            ncRNAs                            :: 11
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 58 of 151
            Pseudo Genes (incomplete)         :: 99 of 151
            Pseudo Genes (internal stop)      :: 14 of 151
            Pseudo Genes (multiple problems)  :: 17 of 151
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP027151.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..6451
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="AR_0363"
                     /db_xref="taxon:573"
                     /plasmid="unnamed10"
     gene            complement(157..468)
                     /locus_tag="CSC00_RS27560"
                     /old_locus_tag="CSC00_5897"
     CDS             complement(157..468)
                     /locus_tag="CSC00_RS27560"
                     /old_locus_tag="CSC00_5897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004187333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004187333.1"
                     /translation="MNISEQYRVAVVSTGHVKKEDAELLDKVCNDDLSGQGLFWIEKNR
                     YGWILRISATEQWRVELTRAGISASALDNIAALNGAGFDWIWFDRDAEQVPELTVWEW"
                     /name="hypothetical protein"
     gene            complement(525..959)
                     /gene="ssb"
                     /locus_tag="CSC00_RS27565"
                     /old_locus_tag="CSC00_5898"
     CDS             complement(525..959)
                     /gene="ssb"
                     /locus_tag="CSC00_RS27565"
                     /old_locus_tag="CSC00_5898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019725164.1"
                     /GO_function="GO:0003697 - single-stranded DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA];
                     GO:0006281 - DNA repair [Evidence IEA]; GO:0006260 - DNA
                     replication [Evidence IEA]; GO:0006351 - DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="WP_004206919.1"
                     /translation="MWKRGENKVILMGRSGKDAELRYTPNGTAIASLTLATEISYSDNE
                     GKEQKETEWHDIVIFGKKAEAAGKYFKKGMMLYFVGRIRNNKWQGTDGKMRSNKEIVID
                     NNGEMQMLPGAGPRNTSAEGQGGIENHDEPPFPDMNDYPQ"
                     /name="ssb"
     gene            complement(1031..1252)
                     /locus_tag="CSC00_RS27570"
                     /old_locus_tag="CSC00_5899"
     CDS             complement(1031..1252)
                     /locus_tag="CSC00_RS27570"
                     /old_locus_tag="CSC00_5899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004187336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004206918.1"
                     /translation="MKEADQKKVNAVMAIADYLGVKNQIEVIEYSAESVQVEWRNPKTK
                     QLIHRDYTFANSFVKDFEKALKSNMKFY"
                     /name="hypothetical protein"
     gene            complement(1407..1691)
                     /locus_tag="CSC00_RS27575"
                     /old_locus_tag="CSC00_5900"
     CDS             complement(1407..1691)
                     /locus_tag="CSC00_RS27575"
                     /old_locus_tag="CSC00_5900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004206917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004206917.1"
                     /translation="MLTLTDIRASNTVLVTEFGGVRAVHFCLHEKLSGNDNDLWFPLAN
                     GADLFEALESIMCINFAAANVVSLEFLRQNGKCKDYRITYNKAKFKPLS"
                     /name="hypothetical protein"
     gene            complement(1735..2175)
                     /locus_tag="CSC00_RS27580"
                     /old_locus_tag="CSC00_5901"
     CDS             complement(1735..2175)
                     /locus_tag="CSC00_RS27580"
                     /old_locus_tag="CSC00_5901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004187338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein"
                     /protein_id="WP_004206916.1"
                     /translation="MSTELNQPAITARIIPNNRRMAFLPRLFGAWYLTGEAGVYNHARS
                     LCADYQGGSWEFVELSCGSGFMYPLSAERFTVSVSGNWFEGELSAEATGIVLTLFTLNH
                     MIWHAHDAGYEHICDMLITQQEKLKLYADQHAEAGLIYRAID"
                     /name="antirestriction protein"
     gene            complement(2376..2681)
                     /locus_tag="CSC00_RS27585"
                     /old_locus_tag="CSC00_5902"
     CDS             complement(2376..2681)
                     /locus_tag="CSC00_RS27585"
                     /old_locus_tag="CSC00_5902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020805649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004187339.1"
                     /translation="MSQNEAYYDTLALIEKGQWCFGSMDEENEERAIKAAKALALFARL
                     NEQDCDGHPVSEIIVDFIANLMHLGEAINFRVLDEESAVIPLVRIAAVHFNAETKS"
                     /name="hypothetical protein"
     gene            complement(2743..3153)
                     /locus_tag="CSC00_RS27590"
                     /old_locus_tag="CSC00_5903"
     CDS             complement(2743..3153)
                     /locus_tag="CSC00_RS27590"
                     /old_locus_tag="CSC00_5903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004187342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1380 family protein"
                     /protein_id="WP_004206915.1"
                     /translation="MHGNVNEICARLLDSFEPQQRISLLIWTAEDVHDCTSDMNLTDDE
                     AEAVLAEIAECSSHSRYGVGKDTVWSLAKQVREDAARDRKIEVNAEALQKVVALAAQFI
                     RLEEIQSGEGAARRLYPQESEALECITKAING"
                     /name="DUF1380 family protein"
     gene            complement(3238..3474)
                     /locus_tag="CSC00_RS27595"
                     /old_locus_tag="CSC00_5904"
     CDS             complement(3238..3474)
                     /locus_tag="CSC00_RS27595"
                     /old_locus_tag="CSC00_5904"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_011154457.1"
                     /translation="MTTLHIREIPTDGAPPICAGRSISDDDLCASCQHLDYRPGHLSAC
                     LLSGCGRDDWPSELDANGYSVACSSYEREKSLD"
                     /name="hypothetical protein"
     gene            complement(3772..4002)
                     /locus_tag="CSC00_RS27600"
                     /old_locus_tag="CSC00_5906"
     CDS             complement(3772..4002)
                     /locus_tag="CSC00_RS27600"
                     /old_locus_tag="CSC00_5906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004187345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hha/YmoA family nucleoid-associated regulatory
                     protein"
                     /protein_id="WP_004187345.1"
                     /translation="MAETVYQARRRFYLLRFRRSRNPDTLEKMYESMRDRGQVPPEDTE
                     AFEAAADHRRAELASGRIWDKIPPHVWQYVK"
                     /name="Hha/YmoA family nucleoid-associated regulatory
                     protein"
     gene            complement(4100..4438)
                     /locus_tag="CSC00_RS27605"
                     /old_locus_tag="CSC00_5907"
     CDS             complement(4100..4438)
                     /locus_tag="CSC00_RS27605"
                     /old_locus_tag="CSC00_5907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004187354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004206912.1"
                     /translation="MAIQSLQFRNGSVSLGDVFVSSWGYEQTNTYFYQVIALRGKKTAV
                     LRRIAAQQVKADSAMSGELKPVLNDFKGEPVTRRICENHEHPSVSIDEYEQAYKTDPNE
                     SHFYSTWG"
                     /name="hypothetical protein"
     gene            complement(4628..5170)
                     /locus_tag="CSC00_RS27610"
                     /old_locus_tag="CSC00_5908"
     CDS             complement(4628..5170)
                     /locus_tag="CSC00_RS27610"
                     /old_locus_tag="CSC00_5908"
                     /inference="COORDINATES: protein motif:HMM:NF025085.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4942 domain-containing protein"
                     /protein_id="WP_264756102.1"
                     /translation="MYTLMSNKQRQEWDRQVAGEEMPPITLENVMSTFRHLNASKADTF
                     TQGLIDIFKSLSWDYKTNNPCMFGKRIIIAPLLDVWRSGWVRFSSDGHTKIDDLARPFY
                     VLDGRNVPDYRVSDGAKLDAFFSENQFNGKVFECDYFSVRYYKKGSAHITFKRPELVEK
                     INNLVASHYPGMLPPRV"
                     /name="DUF4942 domain-containing protein"
     gene            complement(5265..>6451)
                     /locus_tag="CSC00_RS27620"
                     /old_locus_tag="CSC00_5909"
     CDS             complement(5265..>6451)
                     /locus_tag="CSC00_RS27620"
                     /old_locus_tag="CSC00_5909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611418.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ISL3-like element ISPpu12 family transposase"
                     /protein_id="WP_105329839.1"
                     /translation="IACEECGVQGEFVRFGKRDVPYRDLPIHGKRVTLWVVRRRYTCRA
                     CKTTFRPQLPEMVDGFRMTLRLHEYVEKESFNHPYTFVAAQTGLDEKTVRDIFNARAEF
                     LGRWHRFETPRILGIDELYLNKRYRCILTNIEERTLLDLLATRRQDVVTNYLMKLKDRQ
                     KVEIVSMDMWNPYRAAVKAVLPQARIVVDKFHVVRMANDALERVRKGLRKELKPSQSRT
                     LKGDRKILLKRAHEVSDRERLIMETWTGAFPQLLAAYEHKERFYGIWDATTRLQAEAAL
                     DEWIATIPKGQKEVWSDLVRAVGNWREETMTYFETDMPVTNAYTESINRLAKDKNREGR
                     GYSFEVMRARMLYTTKHKKKAPTAKVSPFYKKTIGYGLPDFAEELNYGVDLSTI"
                     /name="ISL3-like element ISPpu12 family transposase"
ORIGIN
        1 ctcaaaaggg tataaggtcg ccataatatt ctctccacgt tatttacaga gcgttttaat
       61 caatatccgc ttttaaactt catgattatt atacgtctaa tgagccatta caggcaagaa
      121 aaaaatgccc cttttcgagg catattttta accggtttac cactcccaaa cggtcagttc
      181 tggcacctgt tctgcatccc ggtcaaacca aatccagtcg aacccggcac catttaacgc
      241 ggctatatta tccaaagcac ttgcactgat ccccgccctg gttaattcca ctcgccattg
      301 ttcagtagca gaaatacgca atatccaccc atagcgattt ttctcgatcc agaacaaacc
      361 ttgaccggac aagtcatcgt tacagacctt gtccagtagt tccgcgtctt ctttttttac
      421 atggccggta ctgacgaccg ccacccgata ttgttcactg atattcatac tccccccctc
      481 tggattggcg gcccgcgtcc tgcgggccgt tctaactcaa atactcactg cgggtaatca
      541 ttcatatccg ggaacggcgg ttcatcatga ttttcaatgc ctccctggcc ttctgcactg
      601 gtgttacgtg gcccagctcc cggcagcatc tgcatttcgc cgttattatc gatcacaatt
      661 tccttattgc tgcgcatttt gccgtctgtc ccttgccatt tgttattacg aatgcgcccg
      721 acaaaataca gcatcatacc ctttttgaag tacttcccag ctgcttcggc tttctttcca
      781 aaaatgacaa tatcatgcca ttccgtttct ttttgctcct tcccttcgtt gtcgctatag
      841 ctgatttctg tagccagcgt caggctcgca atggccgttc cgtttggggt gtaacgcagt
      901 tctgcatctt tgccagaacg ccccatcaga atcactttgt tttcgccacg tttccacata
      961 atacacctca tatatttgat gtttatcagt aaaaaatggg aggattaagg gggatttctc
     1021 cccctcttta tcagtaaaac ttcatgttcg atttcagagc tttttcaaag tcttttacaa
     1081 aggaatttgc aaaagtgtaa tcacgatgaa taagctgttt tgttttagga tttcgccact
     1141 caacctgcac tgattcggct gagtattcga tcacctcgat ttgatttttt acaccgagat
     1201 aatcagcaat tgccattacg gcattcactt ttttttggtc tgcttctttc atttcaactc
     1261 cttcgccagt cggggcgcta ccgcgaaaga ctcaactgcc tttcgatgta ataattatac
     1321 gtctaatgag ccattttatc aactcattag acgtattttt atattttaat tttgttcaaa
     1381 tatgaacatt taatgatgcc agatatctaa cttaatggct tgaatttggc cttgttgtag
     1441 gtgatccggt agtctttgca cttcccgttc tgccgcagga actccagcga gacaacgtta
     1501 gcagcggcaa aattgatgca cataatgctt tccagcgcct cgaacaggtc ggccccattg
     1561 gcaagcggaa accacagatc gttgtcgtta ccgcttaatt tttcatgaag acagaaatgc
     1621 acagcacgca cgccgccaaa ttccgtaacc agcaccgtat tgctggcgcg aatatcagtt
     1681 agtgttaaca tttttccccc tgtcagtatt ggccccctcg cgggggccgc cgtttcagtc
     1741 aatcgcgcgg taaatcaaac cggcttcggc gtgctggtcg gcatataatt tgagcttttc
     1801 ctgctgggtg atcagcatgt cgcagatgtg ctcatagccg gcatcatgtg cgtgccagat
     1861 catgtggttc agggtgaaca gggtcagcac gataccggta gcttctgcgg acagttcccc
     1921 ttcgaaccag ttaccgctaa ccgataccgt gaagcgctct gcgctcagtg ggtacatgaa
     1981 gccgctaccg caagacagtt cgacgaactc ccaggaaccg ccttgataat cggcgcagag
     2041 agaacgtgcg tggttgtaga caccggcctc acctgtgaga taccaggcgc cgaacaggcg
     2101 tggcagaaag gccatgcggc ggttattggg gataatgcgt gcagtgatgg cgggttgatt
     2161 cagttcagta gacattttct gtactcctgc gccagtcggg gcgctaccgt cgaaagaccg
     2221 gattgccttt cgatgtgatt attatacgtc taatgagcca tattaatcaa gcaaaatatt
     2281 cccgcctgcc tgaatatttt caggcgggag aactctttcc cctgtccatt tttgggggca
     2341 ggatcacgcc tgcccccttc tgattcacat gattactatg actttgtttc agcgttaaag
     2401 tgtacggctg cgatcctgac caacgggatc accgcgcttt cctcatcgag cacacgaaaa
     2461 tttatcgctt cccccaggtg catcaggtta gcgataaaat caacgatgat ttcggaaacc
     2521 gggtgtccgt cgcagtcctg ctcattcagg cgcgcaaaca gcgccagcgc cttagcggcc
     2581 ttgattgccc gctcttcgtt ttcttcgtcc atactgccga aacaccattg ccccttttca
     2641 atcagggcca gcgtgtcgta ataggcttca ttctgggaca tgttttttcc tcctgcgcca
     2701 gtcggggcgc taccgtgaaa gttcgctgcg ttactgcgtg aattagccgt taatcgcctt
     2761 cgtgatgcac tccagcgcct cagactcctg cggataaagt cggcgtgcag ctccttcacc
     2821 agactggatt tcttccagcc ggataaactg cgccgccagc gccacgactt tttgcagcgc
     2881 ctcggcattg acctctatct ttcgatcgcg ggcggcatct tcgcgcacct gctttgccag
     2941 gctccagacg gtatcttttc cgacgccata acggctgtgt gaactgcatt ccgcgatttc
     3001 tgccagaacg gcttcggcct catcgtcagt gaggttcata tcactggtgc agtcatggac
     3061 atcttcagca gtccagatca gaaggctgat ccgctgctgt ggttcaaaac tatcgagaag
     3121 ccttgcgcaa atttcattta cgttaccgtg cattgtaaaa ctcctgcgcc agtcggggcg
     3181 ctgccgcgaa agaccggatg cctttcgatg tgattattat acgtctaatg agccatatta
     3241 atcaagcgat ttttcacgct catagctgct acaggcaacg ctgtagccgt ttgcatccag
     3301 ttctgaaggc cagtcgtcac gcccgcaacc tgacagcagg caggcgctga ggtgcccagg
     3361 gcgatagtcg agatgctggc atgaggcgca aaggtcatca tctgagattg agcggcctgc
     3421 acagataggc ggcgctccat cagtgggaat ttctcgaata tgcagcgttg tcactttttt
     3481 tactcctgcg ccagtcgggg cgctgccggt tagggatgca gggggctgtc gccccctgcg
     3541 gcggttcagt ccttaccctt atccttcatg actttaatca gcccggtaat ggctgtaatg
     3601 agggcggcca cggccgtgat aatctgaggg aggttatgga ggatttcaga agaggtcata
     3661 atgcacctgt aaggctgttt aggaaggtac tgatttgaat cagtaaaaac attatacgtc
     3721 taatgagcca tatatgcaag caataaaacg ccccttgtag gggcgctgtg attattttac
     3781 atactgccag acatgcggcg ggatcttatc ccagatgcgt cccgatgcca gctctgcgcg
     3841 gcgatggtcg gcggcagcct caaaagcctc ggtgtcctcc ggcggcacct gtccacgatc
     3901 ccgcatggat tcgtacattt tttccagtgt gtccgggtta cgactgcgcc gaaaacggag
     3961 aaggtaaaaa cgcctccgcg cctgataaac tgtttccgcc atgtatctgc gtcctgagcg
     4021 ccttgttatt tcgcatagta ttcacgtttt ggttgaataa gtcttcgact atacgcccct
     4081 tgcggggcgt agcaggcggt cagccccagg tgctgtaaaa atggctttcg ttaggatcgg
     4141 tcttataagc ctgttcgtac tcgtcaatgc tgacagacgg atgctcatgg ttttcacaga
     4201 tacgacgggt cacgggttcg cctttaaagt cattcaatac cggctttaat tcgccagaca
     4261 ttgcactgtc tgctttcacc tgctgcgcag cgatgcggcg cagtacggcg gttttcttac
     4321 cgcgcagggc gatcacctga taaaaatagg tatttgtctg ctcataaccc cagctggaaa
     4381 caaaaacatc accaagagaa acggagccgt tacggaactg aagggattga atagccatgt
     4441 ttattactcc tgcgccagtc ggggcgctac cgcgaaaagc ctcattgcct ttcgatgtga
     4501 ttattatacg tctaatgagc catataaatc aagcaataaa tacatgcccg gcatgatttt
     4561 ctcaggccgg ggaatacttc ctttccctgt ttatatttca ggccgcaaat gcggcctgcc
     4621 atctgcatta cacgcgaggg ggtaacattc cgggatagtg actggcaacc agattattga
     4681 tcttctcaac cagctccggg cgtttaaacg taatgtgggc gctgcccttt ttgtaatatc
     4741 gcacgctgaa gtaatcacac tcgaacacct taccgttgaa ctggttttca ctgaaaaagg
     4801 catccagttt ggcaccgtca gaaacgcggt aatcaggcac gttacgcccg tccagcacgt
     4861 agaacggccg cgccagatcg tcaattttgg tgtgcccgtc tgagctgaag cgcacccagc
     4921 cactgcgcca gacatcgagc aacggcgcga tgatgatacg cttgccaaac atgcagggat
     4981 tattggtttt ataatcccac gacagggatt taaagatatc aatcagccct tgcgtgaaag
     5041 tatcggcctt gcttgcgttc aggtgccgga acgtactcat aacgttctcc agcgttatcg
     5101 gcggcatttc ttcgcctgcc acctgccgat cccattcctg acgttgtttg ttgctcatca
     5161 gcgtatacat gccggtttcc gacatcagcc gatcccagat ttttccgggt atacggattt
     5221 aatggttgat ggggcacctt caccccatca atctgatacc accctcagat ggttgataga
     5281 tcgactccgt agttgagttc ctctgcgaag tccggcagtc cgtaaccgat ggttttcttg
     5341 tagaaaggag agaccttcgc agtcggtgcc ttcttcttgt gcttcgtggt gtagagcatt
     5401 cgtgcccgca tcacctcgaa ggagtaaccg cgcccttcac ggttcttgtc cttggccagt
     5461 cggttgatgg actccgtgta agcgttggtg acgggcatgt ccgtctcgaa gtaggtcatg
     5521 gtctcttcgc gccagtttcc cactgccctg accagatcgc tccagacttc cttttggccc
     5581 ttcgggatgg tggctatcca ctcgtccagg gcggcttctg cctggagccg tgtggtggcg
     5641 tcccagatgc cgtagaagcg ctccttgtgc tcgtaggcgg ccagcagttg cgggaacgcg
     5701 cctgtccagg tctccatgat gaggcgctcc cggtctgaga cttcgtgagc gcgtttcagc
     5761 aggattttcc ggtctccctt gagagtccgg ctctgggacg gtttcagctc ctttctgagg
     5821 cccttgcgca ctctctctag ggcatcgttg gccatgcgca ccacatggaa cttatcgacc
     5881 acgatacggg cctggggcag cacagccttg accgctgccc ggtaggggtt ccacatgtcc
     5941 atgctgacga tctcgacctt ctgccggtct ttcagcttca tcaggtagtt ggtcaccacg
     6001 tcctggcggc gggtggccag caggtcgagc agggttcgct cctcaatgtt ggtcagaatg
     6061 cagcggtagc gcttgttcag gtatagctcg tcaatgccca ggatgcgggg cgtctcgaag
     6121 cggtgccagc gccccaggaa ctcggcgcgg gcgttgaaga tgtcgcgcac cgtcttctcg
     6181 tccaggccgg tctgtgccgc cacaaaggtg taggggtggt tgaaggattc cttctccacg
     6241 tactcatgca gccgcagtgt catacggaat ccgtccacca tctccggtag ctggggcctg
     6301 aatgttgtct tgcaggcccg gcaggtgtat cggcggcgga ccacccagag agtgacccgc
     6361 ttgccgtgga tgggcagatc acgataggga acgtcacgct tgccgaaccg tacgaactca
     6421 ccctgcacgc cgcattcctc gcaggcgatg g
//
