LOCUS       NZ_CP026769            27054 bp    DNA     linear   CON 08-JUL-2023
DEFINITION  Shigella flexneri Y strain 93-3063 plasmid unnamed1.
ACCESSION   NZ_CP026769
VERSION     NZ_CP026769.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN08330282
            Assembly: GCF_002949575.1
KEYWORDS    RefSeq.
SOURCE      Shigella flexneri Y
  ORGANISM  Shigella flexneri Y
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Shigella.
REFERENCE   1  (bases 1 to 27054)
  AUTHORS   Kim,J.Y., Lindsey,R.L., Garcia-Toledo,L., Loparev,V.N., Rowe,L.A.,
            Batra,D., Juieng,P., Stoneburg,D., Martin,H., Knipe,K., Smith,P. and
            Strockbine,N.
  TITLE     High Quality Whole Genome Sequences for 59 Historical Shigella
            Strains Generated with PacBio Sequencing
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 27054)
  AUTHORS   Kim,J.Y., Lindsey,R.L., Garcia-Toledo,L., Loparev,V.N., Rowe,L.A.,
            Batra,D., Juieng,P., Stoneburg,D., Martin,H., Knipe,K., Smith,P. and
            Strockbine,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-FEB-2018) EDLB, CDC, 1600 Clifton Road, Atlanta, GA
            30333, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 75.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 07/08/2023 02:21:36
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,114
            CDSs (total)                      :: 4,983
            Genes (coding)                    :: 4,204
            CDSs (with protein)               :: 4,204
            Genes (RNA)                       :: 131
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 101
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 779
            CDSs (without protein)            :: 779
            Pseudo Genes (ambiguous residues) :: 0 of 779
            Pseudo Genes (frameshifted)       :: 297 of 779
            Pseudo Genes (incomplete)         :: 436 of 779
            Pseudo Genes (internal stop)      :: 175 of 779
            Pseudo Genes (multiple problems)  :: 125 of 779
            Pseudo Genes (short protein)      :: 5 of 779
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP026769.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This genome has a base modification file available.
FEATURES             Location/Qualifiers
     source          1..27054
                     /organism="Shigella flexneri Y"
                     /mol_type="genomic DNA"
                     /strain="93-3063"
                     /serotype="Y"
                     /db_xref="taxon:424720"
                     /plasmid="unnamed1"
     gene            complement(377..595)
                     /locus_tag="C1P87_RS23665"
     CDS             complement(377..595)
                     /locus_tag="C1P87_RS23665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001510884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_240532962.1"
                     /translation="MNRFLPFNKKGGFMDFMSILGRCLLLPFPVAMFVGCLFPGIDDRL
                     SGMLMSVAVGCLSWYVTRPKNQQTKAE"
                     /name="hypothetical protein"
     gene            complement(626..718)
                     /gene="dqlB"
                     /locus_tag="C1P87_RS27280"
     CDS             complement(626..718)
                     /gene="dqlB"
                     /locus_tag="C1P87_RS27280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000247680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DinQ-like type I toxin DqlB"
                     /protein_id="WP_271359264.1"
                     /translation="MVRSGLLLSGAVAVANALIAILELIRQFID"
                     /name="dqlB"
     gene            complement(1032..1289)
                     /locus_tag="C1P87_RS23670"
     CDS             complement(1032..1289)
                     /locus_tag="C1P87_RS23670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004152108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_021544331.1"
                     /translation="MTIGDGINTVRTGNEVKHITELDALTLCNEWSKLKKENSDLYEYH
                     REINSGWRGVILRLLGIHLPDKKDILLKGINAKGESVYPD"
                     /name="hypothetical protein"
     gene            complement(1382..1846)
                     /locus_tag="C1P87_RS23675"
     CDS             complement(1382..1846)
                     /locus_tag="C1P87_RS23675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293133.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="H-NS family nucleoid-associated regulatory
                     protein"
                     /protein_id="WP_001293142.1"
                     /translation="MSELTKEDEYGIISRTMMNIRSLRVFAREVDFEQLLEMQEKLNVV
                     VEERREEAEREAVERQELEAKRQQAIEYIISLGLDPESLLAPVTADTVKTRRKAKGGVR
                     KAKYRFKDENGEIREWSGNGKRPLALQKLLDEGHFMEDFLIDKLQPGQVE"
                     /name="H-NS family nucleoid-associated regulatory protein"
     gene            complement(1864..2070)
                     /gene="hha"
                     /locus_tag="C1P87_RS23680"
     CDS             complement(1864..2070)
                     /gene="hha"
                     /locus_tag="C1P87_RS23680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin expression modulator Hha"
                     /protein_id="WP_000850859.1"
                     /translation="MKTKQEWLFQLRKCTSRDTLEKVIEINRYKLPLSESEAFYSAADH
                     RRAELVMNKLYDKVPSGVWKYVH"
                     /name="hha"
     gene            complement(2067..4220)
                     /locus_tag="C1P87_RS23685"
     CDS             complement(2067..4220)
                     /locus_tag="C1P87_RS23685"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247728.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003916 - DNA topoisomerase activity [Evidence IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="WP_001235750.1"
                     /translation="MRLFIAEKPAVANDIVKALGGNFTRHDGWFESDNAIVTNCFGHII
                     ESQPPENYNPEYKAWKVETLPLRLYPVKYQPVESAAKQVKTILELIRRGDVTEIVHAGD
                     PDDEGQLLVDEVLEYAGNTKPVKRVLINDNTLPAVKKALANLKDNRDFKGLYLKALARS
                     VADAVYGFSMTRAYTIPAKARGYQGVLSVGRVQTPVLGLIVNRTRANQNHKSSFYYTMT
                     GVFQRGADVIRANWKPGEFAPLTDRKLLDKAWADGTAASLAGKPATVEAAATDDKKTAA
                     PLPFNLVRLQQYMNKKFKMTAQKTLDITQQLREKYKAITYNRSDCSYLSDEQFSEAPQV
                     IDALKSVFPQSLDIDSSRKSKAFNSAKVTAHTAIIPTASVPDVNALSTDERNVYLAIAQ
                     HYLVQFMPEKAYQEVSVAIQCGDESFYARARKTTDSGFEAFLGAETTDEGESEDNDDSA
                     FELLCKIRTGETLTTKEVIVNEKKTTPPPLFTEASLLAALVRVADFVTDPTIKKLLKDK
                     DKDKKDEHGGIGTPATRAAILETLKKRNYITLEKGKLIPTDTGYALIDALPGIAVNPDM
                     TALWSEKQAAIENGDLTVEQFINDLYGELTGMISDVDLGEMKIEPAAPAGQFQRLDSPC
                     PSCGKHIVIRPKGYFCTGCEFKIWSEFYGKKITQAQAEKLVKSGKTDLIKGFKKKSGGT
                     YDTVLVLEDKKTGKLGFPARAKK"
                     /name="type IA DNA topoisomerase"
     gene            complement(4232..4819)
                     /locus_tag="C1P87_RS23690"
     CDS             complement(4232..4819)
                     /locus_tag="C1P87_RS23690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6012 family protein"
                     /protein_id="WP_000275457.1"
                     /translation="MYIHIVPKLYHLMANKCSLKSISIPELDFIIDSESLSVGRPWPNK
                     CLWVGMRKGRKSVNGLVLQTDKKLRWFTTIYTWDIEDMGLIYHQVNTYIEDDDFDMVSQ
                     EILLNGSFDKWSNRVHSAYENKPPARIQPKMESLLNKPGENSHDVWEEFEWGDFLLSRE
                     ESLLLHTIQSERLSTDCSLFKRQPSIESALVI"
                     /name="DUF6012 family protein"
     gene            complement(4846..5166)
                     /locus_tag="C1P87_RS23695"
     CDS             complement(4846..5166)
                     /locus_tag="C1P87_RS23695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001579350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001020837.1"
                     /translation="MNIHLFSEVLFCVWVIALIVILFIVVKYYRRVHYRLNSLSETIKR
                     TQGGVNKRISENRELLELIKNQHPEILDEYPWVSGWLDSQEKFLVALADKSGIDINKSG
                     LI"
                     /name="hypothetical protein"
     gene            complement(5226..5630)
                     /locus_tag="C1P87_RS23700"
     CDS             complement(5226..5630)
                     /locus_tag="C1P87_RS23700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001576899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001218544.1"
                     /translation="MALSPKEKKELQQRFEKQLLPDLDMSFELNGEVYKFNFDKNESGD
                     YIDSFTQAVWGGYQDAEEWEKYGKHQETELPEYPEPVEGWCDCDKCKSMIFHKEKNIYV
                     CLSCHKQTEPFLPIDWNSNDYDWLPYEDEY"
                     /name="hypothetical protein"
     gene            complement(5646..6161)
                     /locus_tag="C1P87_RS23705"
     CDS             complement(5646..6161)
                     /locus_tag="C1P87_RS23705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thermonuclease family protein"
                     /protein_id="WP_001218000.1"
                     /translation="MRIFLSVILFLFTAFQSANAGGIPGALAGILSTLNQEIQGKVIRV
                     LDGDTIEVLQDKKPVRIRLANIDAPEKKQAFGRWSANQLKALLAAQPVTVTYTQTDRYG
                     RIIGHVFTTNGTDASRFMVQSGAAWVYERYNVDESLPALQREAQEQKRGLWVDANPVPP
                     WEWRYKHN"
                     /name="thermonuclease family protein"
     gene            complement(6158..6592)
                     /locus_tag="C1P87_RS26380"
     CDS             complement(6158..6592)
                     /locus_tag="C1P87_RS26380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001576897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000981210.1"
                     /translation="MMNKFSYVNRMLRQVFVFSFITAPSIALFVVFMFFSFNNSIAGSF
                     LKEARGLITDTPSDKVNVCLFEKGVPQDMELTNSTTEHVLKNKCITTLVDAADWQESVD
                     GSIRYFYWSSVVIGFVVWLTFNFRALEELFYRRNRKGDVE"
                     /name="hypothetical protein"
     gene            complement(6674..6913)
                     /locus_tag="C1P87_RS23715"
     CDS             complement(6674..6913)
                     /locus_tag="C1P87_RS23715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001565868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001290043.1"
                     /translation="MSEIRFVTLASDINNIKEVYSDDELKRLLEAVNQNCPARIVLGSV
                     EKGKEVPLKWCFRTIPERISVEEINEVKIYPELF"
                     /name="hypothetical protein"
     gene            complement(6968..7273)
                     /locus_tag="C1P87_RS23720"
     CDS             complement(6968..7273)
                     /locus_tag="C1P87_RS23720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001350475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbM/KikA/MpfK family conjugal transfer protein"
                     /protein_id="WP_000147047.1"
                     /translation="MTGKNRVVLPVFLALGLISTNANASDPCASVLCLYGKAVGQGGGS
                     ECRSAEKDFFNILKKKKGSIRWSKTFDARKAFLNQCSTADPAAISKIMSKFGRVRG"
                     /name="TrbM/KikA/MpfK family conjugal transfer protein"
     gene            complement(7257..7679)
                     /locus_tag="C1P87_RS23725"
     CDS             complement(7257..7679)
                     /locus_tag="C1P87_RS23725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001353737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cag pathogenicity island Cag12 family protein"
                     /protein_id="WP_001353737.1"
                     /translation="MMKKLVFLLISILAGCSSPPEPTPAQFEKANEVINPSLPYVPDFH
                     GVIKSEVSGKGWVYEITSLSGVQARTPTFYYALAHADRVVVTTHDAGLWFRIRDLLKME
                     GATAVVEWRNEKSFLPEQVKIVFIKAQNEVKNDWKK"
                     /name="cag pathogenicity island Cag12 family protein"
     gene            complement(7688..9550)
                     /gene="taxB"
                     /locus_tag="C1P87_RS23730"
     CDS             complement(7688..9550)
                     /gene="taxB"
                     /locus_tag="C1P87_RS23730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxosome-coupling protein TaxB"
                     /protein_id="WP_000847107.1"
                     /translation="MKTFNKSQSVFIFAVMLVAAWFAGSFIFFVLYFSQIKNLKPLKAV
                     FRSIDAYRMDIFTDSLTLSVVTTDIRVLAFVALGAGFVVSLIIPVAALIKLNEKKENIF
                     GDARFATINDIRESNSFTLDGDEKDGIIVGIKDKKIIRYVGAAFSAMGAGTRAGKGAGI
                     VITNLMKYWWSVIILDPKRECFNITSLIRKVILGHEVYKFDPFSPVTHRFNPLYYVSMG
                     TSEGFNQLENLSLIIYPYKTDGADAGSYLNKTAGGVFKSYAVALWFMIKNDKAGLKTLD
                     IEPVFSMSKINQLFERAEPEHLLSFMNDIRSELRGKDKTLADIGVAGLKAFIEMEDKTK
                     AQLKSNFLNGLSPFANPNVANATDGNDFDLRQVRKKRMTIYFCISGDNARLAEKITNIF
                     FQLGIQVNLEKMPTDDPEIKHDCLFLLDEFPSIGAVDYIKSKSGLIAGYKLKLLIVYQV
                     GSQLEEIYSYAGSKTLLASAPCKIVYSASDVKDARELSEAMGTRTVTIGSKSKSRSRGG
                     TSRSESENLIERPLVTTNELLTLKFSEEILAMKGENPIRCEKAFYYLHEYFFGDFVKVA
                     PELANIFPRKKGKLVMPPQKVFENEIVAKGYLAVKDVPDLDKAA"
                     /name="taxB"
     gene            complement(9537..10565)
                     /gene="virB11"
                     /locus_tag="C1P87_RS23735"
     CDS             complement(9537..10565)
                     /gene="virB11"
                     /locus_tag="C1P87_RS23735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001401678.1"
                     /GO_component="GO:0043684 - type IV secretion system
                     complex [Evidence IEA]"
                     /GO_process="GO:0044097 - secretion by the type IV
                     secretion system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type DNA transfer ATPase VirB11"
                     /protein_id="WP_001014667.1"
                     /translation="MNGVIPVSISNKSLDFYKNQVFQSFLDIEGLTEIAVNRPGEIWTE
                     INGDWTFHNNDSVTFDFCKRFSQTLASFRGDEIGDTKPLLSATLESGERVQVVFPPACE
                     RNTISITIRKPSTRQITHKEYVANGFYDYVQSGKKHRTYDDELLDLFRARNIAAFMELA
                     VAAGKTIVFAGATGSGKTTYMKSLIDFIPLNTRLITIEDAEEIKFFIHKNYVHLFYPSE
                     SGSDSGSIITAAKLIKSCLRMKPDRILLAEIKGGDAWDFVKVAGSGHSGSMTSIHAASA
                     KDAIIQMVTKCYQNRECQNLPFDVLRKIIMDSIDIVVHVGRDGVVRHMSDIYYKGAECE
                     NF"
                     /name="virB11"
     gene            complement(10567..11676)
                     /gene="virB10"
                     /locus_tag="C1P87_RS23740"
     CDS             complement(10567..11676)
                     /gene="virB10"
                     /locus_tag="C1P87_RS23740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB10/TraB/TrbI family type IV secretion system
                     protein"
                     /protein_id="WP_000131270.1"
                     /translation="MTDMKKTDDLVDDANQSKLESKPVHDIGDIRNKNNRMRSGFLFGL
                     MAVLVIGIFALKTYKNYFADDQQKASESTGDTSISQVSKIRTGLGQNFDPVENKAIINP
                     GATGSGNTVSDGHKEVPQEGFRKYLSIPVAGQGGSQTGASGSSRTSEPQEERKESKENV
                     PGKSGMKVTAINLDPDLYIEENRLIPCALTTRFVSDVAGRISCVFTEDVWSANHHTKLL
                     EQGTKAFGRYQTGTLNHGQGRMFVMWEQLRTPDNKRIDMVNTAAAGPLGEAGIDGWIDS
                     HFWERFGGSLMLSMVQDVAAAAADNAPGKDRNVDYTENSRQAMAEMAKVALENSINIPP
                     TMYKNQGDIITIMVGEDIDFSDIYELKVK"
                     /name="virB10"
     gene            complement(11669..12577)
                     /gene="virB9"
                     /locus_tag="C1P87_RS23745"
     CDS             complement(11669..12577)
                     /gene="virB9"
                     /locus_tag="C1P87_RS23745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001299943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type conjugative transfer protein VirB9"
                     /protein_id="WP_001353735.1"
                     /translation="MMKKLFIATCLLLPGLVYSAATPLPSGFDARMQTVSYNGANTTVI
                     RSKTGFLTSVVFDEGEAVISAKAGFPAGWEITTDDNVVYINPRPVVQEQEGDEGEKLKK
                     VFQPTEKEWDTNLFVRTTKRIYSLDLILLSEEKQAQPAYVVQFRYPSEIAKKNAEEVRL
                     AKEKQEKLRQKKLISESFEKADAPKNWNYFMRVNEKYDSRRIAPDFAYDNGIFTFLGFN
                     SGKAFPAPFAVRDGQEQTLAFNVETKGKYKIMVIHNVNDKFVLRYGNSVVGVVNKSFGK
                     VLTDQRNTSSPAVERVEVNND"
                     /name="virB9"
     gene            complement(12574..13260)
                     /locus_tag="C1P87_RS23750"
     CDS             complement(12574..13260)
                     /locus_tag="C1P87_RS23750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_001290764.1"
                     /translation="MSEKIEKKIETAKSFERQLYAENERSKKNAWRVAVAASLLSLCLG
                     AAICVLVPLKEKELAIVAVGEKTGRTELITQVKQEKILQSEALGRYFVNTYITLREGYN
                     YPSLQYDYETVQLYSSNTVKDDYLRLYNSDMAPDKIYHNNGSYVAVEVISNIISDATAP
                     DKLASVRFKKTTRNFTTGQVSVSYWTARVTYRFEPEKSVKSSSRELNPLGFTVTSYQTD
                     REARGE"
                     /name="type IV secretion system protein"
     gene            complement(13775..14869)
                     /locus_tag="C1P87_RS23770"
     CDS             complement(13775..14869)
                     /locus_tag="C1P87_RS23770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001677777.1"
                     /GO_process="GO:0030255 - protein secretion by the type IV
                     secretion system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_001353734.1"
                     /translation="MAQGFFVKYNSTVMDSVDKISSSYQTQFANDIMSLVTVSVTLYVL
                     WKGYQILASKTQTPLQDLVWDLSKFAIIIMFITNADGYLTAATDALQGMKDGFSGGVSV
                     WQTLDNLWKSTQNLGAEIYSLDKSTYVKDQGVVGQFLIWTGSLILMAVSVVVFLTADVT
                     MKLLIITAPIFIFCLMFGFIRSMFNNWLQSLFSSILTVLFASLVIRIAMDFQGMILSHA
                     IRAAQTGNVNLVSTGAMGFMAGFLGALLVLIAKGFAVQLAGAGVEGAVQGAAMMGLGAA
                     GMATGKSLMLGGRAGLGFGLGMAGRTGMNSLSGKAGNLMGRGARTAAEWAGEKGYQALA
                     PTGALGMKARRLASLEKARARNAA"
                     /name="type IV secretion system protein"
     gene            complement(14881..15597)
                     /locus_tag="C1P87_RS23775"
     CDS             complement(14881..15597)
                     /locus_tag="C1P87_RS23775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_000832281.1"
                     /translation="MKRVKTFMLISLLTASFYSSAGIPVAVDASPEWAVEAARWTERLK
                     QWSETAKHYQGQIQAYKDQLATATGIRNIAAFTNELSNLQSELTNIYKQGNSYISDFTS
                     NPEGALSSQAKNLFSKYGAFDMCNTGYERNDNLCKARIVSTAASIEQGNEINKQLSSAM
                     SQIQSLSSRIEASKDIKESQDLANALQAQSLKMQAIKMQYDVWNNKNKADHEMLLTHEQ
                     EAFIKQQKEAEPLTFD"
                     /name="type IV secretion system protein"
     gene            complement(15609..18356)
                     /locus_tag="C1P87_RS23780"
     CDS             complement(15609..18356)
                     /locus_tag="C1P87_RS23780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB4 family type IV secretion/conjugal transfer
                     ATPase"
                     /protein_id="WP_000105980.1"
                     /translation="MSTLYKAMTRPAMYVGVPVVPLTVVAGALFLAGVYISKLIWLAIP
                     VAVFILRMITKQDDHIFNLYFLKLKMLGNSVCNRFFGARAFLSGQYEAVEIDEFVNAMK
                     LNERITTGKYIPYSSHVDKNIVKTKNGDYVATWQLMGINFESISAEMLETIDSQVATLV
                     RSFSGLPVSFYNHSCRASFYDAFTTKSGNKYADIISDCYYGSMKKNKFKGNTLYFTLIY
                     RPDGRVEKLEKRKKSIKEKKDDIHIHVKRMNEMINTFSGALDKFTCKLLGMYEENGKVF
                     SSQLSFYNYLLTGKLQKIRVTDSPVYNVLGGVDVFFNHDTGQICRIDGNKFFRSIEIKD
                     FCSETASGVFDVLQYSDADYIITHSYTSMSKSEALSTIKRAEKQLKSTEDDAVTQLQEL
                     EKAKNDIVSGDISFGYYHFTIMVMADSIRELDESVSKITADFTDLGIIPALSTMSLPAA
                     YFAQLPAVFHLRPRLSPVSNVNFVELASFHNFYQGKRDKNCWTEAVAILKTPSKQAYYL
                     NLHNSVLFKDETGEKNLANTKVIGTAGSGKTMFLSYLACSLQKYNNPETFADSAKNKKL
                     TCVFLDKDRGAELCIRMLGGEYYTVKSGEPTGWNPFALEATKRNRIFVKQLMEILCTRN
                     GERLSTRERLLISESVDAVMDFPPGEMREYGITRMLEHLMQRDDRDEQENGIILRLSQW
                     ANSQAHGWVFDNAKDTFNIQHVNNFGIDGTEFLDDPMVCAPITFYLLYRITQLLDGRRL
                     VIFLDEFWKWLQDEAFSDFVYNKLKTIRKLNGLVIPATQSPDEILKNKISRAVVEVCST
                     SIYLANPDADYNDYVEGLKLTPEEFNIIKNLDPMSRQFLIKKSSLKKGDGKSFSALATL
                     DLSGLGGYLKILSASADNLEIFESIYHEGMEPDDWVPEYLERAI"
                     /name="VirB4 family type IV secretion/conjugal transfer
                     ATPase"
     gene            complement(18375..18701)
                     /locus_tag="C1P87_RS23785"
     CDS             complement(18375..18701)
                     /locus_tag="C1P87_RS23785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbC/VirB2 family protein"
                     /protein_id="WP_000008644.1"
                     /translation="MSFKKSVCNCISSSVTAVMQRKNKVVMAVAGATVASPAFADGFSK
                     AETLLQKVKTGLGGLSLVTVTIACLWVGYKVLFGGSTIRECSPIIIGAIVIASAAEVAS
                     MMVN"
                     /name="TrbC/VirB2 family protein"
     gene            complement(18715..19335)
                     /locus_tag="C1P87_RS23790"
     CDS             complement(18715..19335)
                     /locus_tag="C1P87_RS23790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012908959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing protein"
                     /protein_id="WP_000157549.1"
                     /translation="MASLFPALLLCAASVHPDTINDIARVESGFNPYAVAEIIPERERG
                     SYGKSVISHMPKSKEEALTVIREIENRKRRYSVGLMQITSSNFSFYSTSAEKLLDSCEN
                     LSVFEKIIVDCYKRGRSLENALSCYYTGNFSNGKRKEKEFNNTSYVERIGYTGNEKKYV
                     VPGTRSNGGEQRKNRSHNASVIWPETILKSAFVDNSHPTKVIN"
                     /name="lytic transglycosylase domain-containing protein"
     gene            complement(19692..19907)
                     /locus_tag="C1P87_RS23795"
     CDS             complement(19692..19907)
                     /locus_tag="C1P87_RS23795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EexN family lipoprotein"
                     /protein_id="WP_000760375.1"
                     /translation="MKKYLLFALPFFVVGCSEEVKSVDWWGQHLTEAKQKQAECEKSGS
                     DSQNCKNVKQALFIQSQKDAPVPTFD"
                     /name="EexN family lipoprotein"
     gene            complement(19904..20197)
                     /locus_tag="C1P87_RS23800"
     CDS             complement(19904..20197)
                     /locus_tag="C1P87_RS23800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134733.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]; GO:0016987 - sigma factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]; GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-like helix-turn-helix DNA-binding
                     protein"
                     /protein_id="WP_000134733.1"
                     /translation="MTEHDAICISALHQIFSDEEHLSEQQKDIILMYAYGYTLNEIADF
                     KGLKPSTVRKYLDSVRAELGGVSLAGIRTLVLIRTNALLVSSLSRISERGNL"
                     /name="sigma factor-like helix-turn-helix DNA-binding
                     protein"
     gene            complement(20274..21503)
                     /gene="taxC"
                     /locus_tag="C1P87_RS23805"
     CDS             complement(20274..21503)
                     /gene="taxC"
                     /locus_tag="C1P87_RS23805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001329504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA relaxase/nickase TaxC"
                     /protein_id="WP_016231858.1"
                     /translation="MGVYVEQEYRIKRAKGTGRDPKSPKLSGRHIHASKSAFNHKVRHG
                     ADKKAYTWTPTKEVTFKITGSGKTAAGIKNGIDYITRNGELEAYCYDGKGSEQTGKGED
                     FNREFTSTLSKGNDYSRTYRGENIDHVKNMVFSPPPEAGVSREDALKATVEFLKETYPN
                     HAFVAVYHDDKEDHPHVHVNIKLRDEETGRRLRLTKSETRKFRNGFHRKLKGMGYDVTA
                     TWKKDPERKREIERLQAENPKRLRNVYKVVDFGETSYQNKAGEKRTPFLTYETLKGGKQ
                     VTIWGKDLKNHFESEKLQPGTLIKVKKLAPTLVRSPMFNDDGTVAGYRETHRNNWQIEN
                     IALERNRERQVHERETRQPEESDVKKQLSRKHEQGHNIGFALEYGFTKDSEEHKKLRIQ
                     QERNWKGLGF"
                     /name="taxC"
     gene            complement(21507..22010)
                     /gene="taxA"
                     /locus_tag="C1P87_RS23810"
     CDS             complement(21507..22010)
                     /gene="taxA"
                     /locus_tag="C1P87_RS23810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000781813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxosome-coupling protein TaxA"
                     /protein_id="WP_000781814.1"
                     /translation="MKMIAFRLSDDELKFAEHNAILSGFTSINAFAKHNVLNIETKPVN
                     IPVNNEPAKLVSVRLYPHEIELVKRNAALHGMSMSREIAIRVRQSLLKSEVCLYPDEVK
                     ELKKLSTAVDRVGRNIHFIIKGERFCTVNDPDFRKDVIEVIELCKRIDSKLETLTKSVV
                     NRFG"
                     /name="taxA"
     gene            complement(22373..22720)
                     /locus_tag="C1P87_RS23820"
     CDS             complement(22373..22720)
                     /locus_tag="C1P87_RS23820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="WP_000681613.1"
                     /translation="MKHLKYKGYLGTVEPDFENNVLYGKLAFIRDLVTYEASTLAELEQ
                     EFKTSVDLYLQSCVEDGKEPDTPFKGVFNVRLDPELHRRVAEMAMEEDLSLNAFVNKAL
                     EKEVSNHRAGA"
                     /name="type II toxin-antitoxin system HicB family
                     antitoxin"
     gene            complement(22717..22965)
                     /locus_tag="C1P87_RS23825"
     CDS             complement(22717..22965)
                     /locus_tag="C1P87_RS23825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005653200.1"
                     /GO_function="GO:0003729 - mRNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family toxin"
                     /protein_id="WP_000520549.1"
                     /translation="MGKTDKLLAKFLNSKKTFEWDELVVLFSSLGYVKKEMQGSRVRFF
                     NAEINHTILMHRPHPESYIKGGTLKAIKQNLKEAGLL"
                     /name="type II toxin-antitoxin system HicA family toxin"
     gene            complement(23275..23568)
                     /locus_tag="C1P87_RS23830"
     CDS             complement(23275..23568)
                     /locus_tag="C1P87_RS23830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001401669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001401669.1"
                     /translation="MLTEAKKMAVEMMFWPACPVDDDYCFDAIMYTSVIDKKFEDEHGV
                     YLHQVYKELCSTPELKKLLKKKAIKLIAFKYDIDLDSANKILMKNMLRRIEN"
                     /name="hypothetical protein"
     gene            complement(23583..23957)
                     /locus_tag="C1P87_RS23835"
     CDS             complement(23583..23957)
                     /locus_tag="C1P87_RS23835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail-associated lysozyme"
                     /protein_id="WP_000844303.1"
                     /translation="MKSVYVVGKGLIVAGNKITIDGKEHVSVENSENIVVTDDCIKIGN
                     KTVVFKGRSIKVEIHGNVNKIVTENADVSIHGNAGDVETVSGDVDCHQVNGDITTVSGD
                     VTCGDVSGDVTTVSGDINRK"
                     /name="tail-associated lysozyme"
     gene            complement(24009..24227)
                     /locus_tag="C1P87_RS23840"
     CDS             complement(24009..24227)
                     /locus_tag="C1P87_RS23840"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001407769.1"
                     /translation="MHKDTGQQYVVIFTDNNKIRDYKTGIVPQFGELKQSDVDLVLFYR
                     DEYEKYFDSLKDGDECLSFKDFIECLR"
                     /name="hypothetical protein"
     gene            complement(24762..24989)
                     /locus_tag="C1P87_RS23850"
     CDS             complement(24762..24989)
                     /locus_tag="C1P87_RS23850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000801440.1"
                     /translation="MKPDNTPENVKKLRLKAGLTQKECSHIYGVGLRTWQKKEEVNTQN
                     SQSLSLVEFEFLLLLAGEHPEYVLCKRESK"
                     /name="hypothetical protein"
     gene            complement(24979..25227)
                     /locus_tag="C1P87_RS23855"
     CDS             complement(24979..25227)
                     /locus_tag="C1P87_RS23855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001230706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001230706.1"
                     /translation="MRKNKGDVTYFLEKEGDNYRLTKRIKARTNVKIGNKTTKITLYDA
                     VLNENELQHIDFTCAGLREDDETPVKNLIKEFMLNET"
                     /name="hypothetical protein"
     gene            complement(25224..25766)
                     /locus_tag="C1P87_RS23860"
     CDS             complement(25224..25766)
                     /locus_tag="C1P87_RS23860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001401654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001083906.1"
                     /translation="MNSFFEQYHPVFEVVCRILGNGWRVNKLDDCSSRIKLTSPQFKNY
                     SVHIRMEKDRFSVVGSVDSRSWRSPHHVCTLSRKRNPVDIAADIERKILVNASQEVLQA
                     IEYEKHQVEKKDEILILKGMLSQLVQLESWYGALTGFKAENGLNGKVTEQGDSYDLQIR
                     GLSIDQLVKITGYLKQL"
                     /name="hypothetical protein"
     gene            complement(25871..26386)
                     /locus_tag="C1P87_RS23865"
     CDS             complement(25871..26386)
                     /locus_tag="C1P87_RS23865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025391.1"
                     /GO_process="GO:0006457 - protein folding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="J domain-containing protein"
                     /protein_id="WP_001025395.1"
                     /translation="MNIQEALNVFGLSGELTEKDIKAAYRKAALKYHPDRNPLGAELMK
                     AVNAAFDVLMANIDKINQFQSTDEHARYNYGDDLEKVLNVLSGLSGLVFEVIGNWVWIS
                     GETITHKETLKEIGCKWAAKKKQWFYRPDEHKSYWNREEHTIEEIRAKYGTTGQRRATG
                     WQRVETRA"
                     /name="J domain-containing protein"
     Typing          complement(20278..21503)
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="99.267"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(7692..9550)
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="98.871"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(11673..12577)
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.338"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(12578..13260)
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.561"
                     /coverage="100.0"
                     /evalue="4.13e-137"
     Typing          complement(13800..14869)
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="7.060000000000001e-173"
ORIGIN
        1 tatttccatg tgatgtacgc atatgtatgt cacatggaaa tactatagtg tatgtcataa
       61 tgaattacaa taacgtacat catgaagaaa tacactattg tatgtcagta tgatgtactc
      121 gttggttggt cacttgaaag caaaagtgac agcgttactt tcggtatcct cccttgctgc
      181 gaaaccttgt ggcaatacag caatgagtat gcttagttac aacattcaaa attaagcgat
      241 tagattccgc ccgtacgggc ggggcgcgcc ctttctgtag tggggagggg cagggaggtt
      301 atgtttgctg gatgagcgga ggatggaatg aactattaga atgttgtaac taaaaggtat
      361 cccaattaaa ggccacttac tcggcctttg tctgttggtt cttcggtctg gtgacatacc
      421 acgataaaca tcccacagca acactcataa gcattccgga taagcgatca tcgatgccag
      481 gaaacaggca accgacaaac atcgcaacag ggaaaggaag aagtaaacag cgccccaaaa
      541 tgctcataaa atccataaat cctccttttt tgttaaaggg caggaagcgg ttcacttcct
      601 gcccttagtt acgtttccgc tgtcatcagt cgatgaactg gcgaatcagt tccagaattg
      661 caatcagcgc gtttgcaacg gcgacagcac cggaaagcaa taagcccgat ctcaccagtc
      721 gggctttttt gcgcctgtcg ttcggctgca cttccgtttt ttctccctca tttgaggggc
      781 attctctttc agtttttttg ttgcggtcga tgctgccggt tgcgctggcc atctgctcga
      841 tgctgatgcc ggcattttca tgattcgcct tttttcagta agttacaaca cagccgagat
      901 aaaaacaggt agtcagtttt tttgatggat acagcatcgg cggtgcgcta cgtgaaatct
      961 gacaaaaaga gaaggggact ggaggacaga ttttgcggag aacgggcaga agaaaggccg
     1021 cttgcgcggc ctcagtctgg atagacagac tcacctttgg cattaatacc tttgagcaaa
     1081 atgtcttttt tatccggcaa atgaataccc agcaaacgca aaatgacacc tcgccagccg
     1141 gaattgattt ccctgtgata ttcataaagg tcactatttt cttttttcag cttagaccat
     1201 tcgttacaga gtgttagcgc atcaagttct gtgatgtgtt taacttcatt tccagttctg
     1261 actgtattaa ttccgtcacc aatagtcata atccctcaca attttgctta ccagcgccgc
     1321 aagcggctcg gtcaacccct caaccgccgc aaagcaagtt tgcgacggca tcacgattat
     1381 tttattcaac ctgcccaggt tgcagtttgt caatgaggaa atcttccatg aaatggccct
     1441 catcaagcag cttctgtaaa gcaagcggac gcttgccatt accagaccat tctctgatct
     1501 cgccattttc atccttaaag cggtatttag cctttcttac tccgcctttg gctttccgcc
     1561 tggtttttac tgtatctgct gttacaggag caaggagtga ttcgggatca agacctaaag
     1621 atatgatgta ttcaatggcc tgctgacgtt tggcttcaag ttcctggcgt tcaaccgctt
     1681 cacgttcagc ctcttcacga cgttcttcaa caacaacgtt cagtttttcc tgcatttcga
     1741 gcaattgctc aaaatcaact tcacgggcaa aaacacgcaa tgaacgaata ttcatcatag
     1801 tacggctgat aatgccgtat tcatcttctt tagtcagttc gctcatataa ttaatcctct
     1861 tatttagtgt acgtacttcc agacgccgga aggcacctta tcataaagtt tattcatcac
     1921 cagttctgct cggcgatgat ctgcggcaga ataaaatgcc tctgattctg ataaaggcag
     1981 tttgtaacgg ttaatctcaa taactttttc aagagtatct cttgatgtac attttcttaa
     2041 ctgaaaaagc cattcctgct ttgttttcac ttcttagccc ttgccggaaa acccagtttc
     2101 cctgttttct tatcctcaag gacaagaact gtatcatacg ttccaccact tttcttttta
     2161 aatcccttaa tcaaatcggt tttccctgat ttaaccagtt tttcggcctg tgcctgggtg
     2221 attttcttac cataaaactc actccagatt ttaaattcac atccggtaca gaaataacct
     2281 ttcggcctga taacaatatg tttaccacag gaagggcagg gagagtccag gcgttgaaac
     2341 tgccctgctg gcgcagcggg ttcaatcttc atctcgccca ggtcaacatc agaaatcatg
     2401 cctgtcagtt caccgtacag atcattaata aactgttcaa ccgtcagatc gccattttct
     2461 atggcagcct gcttttcaga ccataatgct gtcatatcag gattaaccgc tataccaggc
     2521 agggcatcaa taagcgcata tccggtatca gtaggaataa gtttcccttt ttccagcgtg
     2581 atatagtttc ttttcttcag cgtttccaga atggctgcgc gggtagctgg cgtaccaatg
     2641 ccaccatgtt catctttttt gtctttatcc ttatccttca acaatttttt aatcgttggg
     2701 tcagtgacaa aatccgcgac acgaacaagc gcagcaagca aggaggcttc ggtgaataac
     2761 ggcggcggtg ttgttttctt ctcattaaca ataacttctt ttgtcgtcag tgtttctcct
     2821 gtgcgaattt tacagagcag ttcaaaagcg gaatcatcat tatcttctga ttcaccttcg
     2881 tctgtggttt ccgcgccaag aaacgcctca aatccgctgt cagttgtttt tctggcacgg
     2941 gcatagaacg actcatcacc acactgaatg gcaaccgata cttcctggta tgctttttca
     3001 ggcatgaact gaacaagata gtgttgtgcg atcgccaggt aaacattgcg ctcgtcggtg
     3061 ctgagtgcgt taacatcagg cacactggcg gtcgggatta tagcagtatg cgcagtcacc
     3121 tttgcactgt taaacgcttt gcttttacgt gaagaatcaa tatccagcga ctgaggaaag
     3181 actgatttca gggcatcgat aacctgcggc gcttcgctga attgttcatc agataaatat
     3241 gagcaatcag agcggttata agtaatcgct ttatattttt cacgtaattg ttgcgtaata
     3301 tccagcgttt tttgtgccgt cattttgaac tttttgttca tgtattgctg gagtcgtacc
     3361 aggttaaagg gcaacggtgc agccgttttt ttatcatcag ttgctgccgc ttcaactgta
     3421 gccggttttc ctgcaaggga ggctgccgtt ccgtctgccc acgctttatc aagtaattta
     3481 cggtctgtca gcggagcaaa ttcccctggc ttccagttcg ccctgataac atcagcacca
     3541 cgctgaaaga ctccggtcat ggtgtagtaa aaactggatt tatggttctg gttagcacgg
     3601 gtacgattca caatcaggcc aagaacggga gtctggacgc gcccgacaga cagaacgccc
     3661 tgatatcctc tggcttttgc aggaatggtg taagcacgcg tcatggagaa gccatagacg
     3721 gcatcagcaa ctgaacgcgc cagcgcctta aggtaaagcc ctttgaaatc acgattatct
     3781 ttaagatttg ccagtgcctt tttcactgcc ggaagcgtgt tgtcgttaat cagaacgcgc
     3841 tttacgggtt ttgtgttgcc tgcatattcc aggacttcat caacaagtaa ctgtccctca
     3901 tcatcaggat cgccagcgtg aacaatttca gtcacgtctc cacgtctgat aagttcgaga
     3961 atcgttttaa cctgttttgc ggcactttca acaggctgat acttcacggg ataaagacgt
     4021 aaaggaagcg tttcaacctt ccaggctttg tattcaggat tatagttttc cggcggttgt
     4081 gattcgataa tatgaccaaa acagttagtc acaatggcgt tatcactttc aaaccagcca
     4141 tcatggcggg taaaattgcc accaagtgcc ttaacaatat catttgctac tgcgggtttt
     4201 tctgcgataa aaagtctcat cttattatcc tttaaataac taatgcactt tcaatagacg
     4261 gttgtctttt gaataaagag caatctgtac tcaatcgttc agactgaata gtgtgaagta
     4321 aaaggctttc ttctctggac agaaggaagt caccccattc gaactcttcc cacacatcat
     4381 gactgttttc accaggttta tttaataagg actccatttt gggctggatt ctggctggag
     4441 gcttattttc ataagctgaa tgaaccctgt tactccactt atcaaaagaa ccatttaaaa
     4501 gaatttcctg tgaaaccata tcaaaatcat catcttctat ataggtattg acttgatggt
     4561 aaattaaccc catatcttca atatcccagg tgtatatagt agtaaaccat cttaattttt
     4621 tatctgtttg caaaacgagg ccattaactg acttccttcc ttttcgcatt ccaacccata
     4681 aacatttatt aggccacggt ctgcctacag acaatgattc actatcaatt ataaaatcaa
     4741 gctcaggtat ggaaatagat ttaaggctac atttattagc catgagatga taaagtttag
     4801 gaacaatatg tatatacata gtaatttcct ttatctttag tgtgctcaaa taagtcctga
     4861 tttgttgata tcgataccag acttatcagc aagagcgacc aaaaactttt cctgtgaatc
     4921 aagccaacca cttacccacg gatattcatc aagaatttca ggatgttgat tctttataag
     4981 ttcaagcagt tctctgtttt cagatattcg cttattaaca ccgccctgtg tgcgctttat
     5041 cgtttcagac agtgaattga gtctgtaatg gacacgcctg taatatttaa caactataaa
     5101 taaaatcaca atcaaagcta taacccatac gcagaacaat acttctgaaa ataaatggat
     5161 attcatttaa gcctccttaa ttttatgccg ccatttcatc cattatgact gtgaagtatt
     5221 cagcattagt attcatcttc ataaggtagc caatcgtaat cgtttgagtt ccagtcaatt
     5281 ggaagaaatg gctctgtttg tttatggcag gagaggcaaa cataaatatt tttctcttta
     5341 tgaaaaatca tcgacttaca tttatcacag tcgcaccaac cctcgactgg ttcagggtat
     5401 tcaggtaatt ctgtctcctg atgtttacca tatttttccc attcctcggc atcctgataa
     5461 cctccccata ctgcttgtgt aaaactatcg atatagtcac ctgactcatt tttatcaaaa
     5521 ttaaatttat atacttcgcc atttagttca aatgacatat caaggtcagg tagtaattgc
     5581 ttttcgaagc gttgttgtaa ctctttcttt tctttgggtg ataaagccat aaaaacctct
     5641 atcagttagt tatgtttgta tcgccactcc cacggtggaa ccggatttgc atcgacccac
     5701 aaaccgcgtt tttgttcctg cgcttcccgt tgtagagccg gtaatgactc atccacgttg
     5761 taacgttcat atacccatgc agcgccagac tgaaccataa agcggctggc atccgtgccg
     5821 ttcgtcgtga acacatgacc gataatgcgt ccgtagcggt ctgtctgcgt gtacgtcacc
     5881 gtaacaggct gtgctgcaag cagagcttta agctgatttg ctgaccagcg cccgaaagcc
     5941 tgttttttct ccggtgcatc gatgtttgcc aggcgaatcc tgacgggctt tttgtcctgt
     6001 aaaacttcga ttgtatcgcc atcgagaaca cgaataactt tcccctggat ttcctggttt
     6061 aatgtagaaa gtattcctgc taaagcacca ggtattccac ctgcatttgc agactgaaaa
     6121 gcagtaaaca ggaataaaat tacgcttaaa aaaatcctca ttcaacgtct ccttttctgt
     6181 ttctacgata aaatagttct tccagtgcac gaaaattaaa ggtaagccag accacaaagc
     6241 caataacaac tgacgaccaa taaaaatatc gaatggaacc gtcaacagat tcctgccagt
     6301 cagcagcatc aactaacgtt gttatacatt tattttttaa tacatgttca gttgtggagt
     6361 ttgtcaactc catatcctgt ggtacgccct tttcgaaaag acagacgtta accttatcag
     6421 aaggagtatc ggttataagc cccctggcct cttttaaaaa tgaaccagca attgagttat
     6481 taaacgaaaa aaacataaaa acaacaaata aagctattga tggggccgtg ataaaactaa
     6541 aaacaaaaac ttgccgaagc atacgattga cataactaaa tttattcatc ataaaactaa
     6601 cgcccttcgg ttgttcaacc ccgcagattc cagattaaaa tctggaatct gcggcgtttg
     6661 cctttatttc agttcagaat aactctggat aaattttaac ctcattgatt tcttcaactg
     6721 aaatacgctc tggtattgtc ctaaaacacc acttgagtgg tacttctttc cccttctcca
     6781 cactacccaa cacaattctg gctgggcaat tctgattaac agcttccagc aaacgtttta
     6841 actcatcatc agaataaact tctttaatat tgttaatgtc ggatgccaga gttacaaatc
     6901 ggatttcgct cataattttt ctcctgtata tcccttgata cccgttggcg cgggtatcag
     6961 gttttaatta acctctgaca cgaccaaact tactcatgat tttcgatata gcagcaggat
     7021 cagccgttga acactgattc agaaatgctt tacgggcatc aaaagtttta ctccagcgaa
     7081 tgcttccttt tttctttttc agaatattaa aaaaatcctt ttcagcactt ctgcactcac
     7141 tccctccacc ttgcccgact gcttttccat ataagcaaag taccgaagcg caagggtcag
     7201 atgcattagc atttgttgat attaatccta acgccagaaa gacaggtaaa accactctat
     7261 tttttccagt catttttcac ctcattttgt gctttaatga aaactatttt tacctgttca
     7321 ggtaaaaaac ttttctcgtt tcgccattcc acgactgctg ttgccccttc catcttcaac
     7381 agatctctga ttcgaaacca cagcccagca tcatgtgttg tcactaccac cctgtccgca
     7441 tgagccagag cgtaatagaa cgtcggcgtt ctggcctgta caccggataa ggaagtgatc
     7501 tcataaaccc atcctttacc gctaacttct gactttatga cgccgtgaaa atcggggaca
     7561 tacggcaatg agggattgat cacttcattt gccttttcaa actgcgcggg tgttggctct
     7621 ggcggtgatg aacaaccagc aaggatagaa atcaataaaa acactaactt cttcatcatg
     7681 ttctccttta tgccgcttta tcgagatcag gaacatcttt tactgccaga tacccttttg
     7741 cgacgatttc attttcaaat actttctgtg gaggcataac cagctttcct ttcttcctgg
     7801 ggaaaatatt tgcaagttcc ggagcaacct tcacaaaatc accaaagaaa tactcatgga
     7861 gatagtagaa tgccttttca caacgaatcg ggttttctcc cttcattgcc aggatttctt
     7921 cactaaattt cagtgtcagt aattcatttg ttgttaccag tggacgctca ataaggtttt
     7981 ctgattcaga tctcgatgtt cctccacgac tacgactttt gcttttcgaa ccgatagtta
     8041 ctgttcgtgt tcccatcgcc tctgataact cccgtgcatc tttaacatca gaagcagaat
     8101 aaacgatttt gcagggtgca cttgccagta atgttttact gcctgcataa ctatagattt
     8161 cctcaagctg agagccgacc tggtaaacaa tcaacaattt cagcttgtaa ccagcaataa
     8221 gaccagattt actcttgatg taatctacag caccaattga cgggaattca tccagtagaa
     8281 aaaggcagtc atgctttatt tccggatcat ccgttggcat cttttcaaga ttcacctgta
     8341 taccaagctg aaagaaaata tttgttattt tttcagccaa cctggcatta tcaccagaaa
     8401 tacagaaata aattgtcatc cgttttttcc gcacctgccg caaatcaaaa tcatttccat
     8461 cagtagcatt cgccacattg gggttagcaa acggtgataa tccattaaga aagttgcttt
     8521 tgagttgtgc ttttgtttta tcctccatct caatgaatgc cttaaggcca gcgacaccaa
     8581 tatcagcaag cgttttgtct ttccccctta attctgaacg aatatcattc atgaatgaaa
     8641 gaagatgttc gggttctgca cgctcaaaaa gctgattaat tttagacatt gagaagacag
     8701 gctcaatatc aagcgttttt agtccagcct tatcattctt aatcataaac cataaagcga
     8761 cagcataaga tttaaaaaca ccacccgccg tcttattaag atagctacca gcatccgcac
     8821 catctgtctt ataggggtaa ataatcaacg aaagattttc aagctggtta aaaccttcac
     8881 tcgttcccat gctgacataa tacaaagggt taaagcggtg cgttaccgga ctaaagggat
     8941 caaatttata aacctcatga cctaaaatca ccttcctgat aagactggtg atattaaaac
     9001 actccctttt tggatcgaga ataataacac tccaccagta cttcataaga ttagtgatga
     9061 ctataccagc acctttacca gcccttgttc cggctcccat agcactgaat gctgctccca
     9121 catagcgtat tattttcttg tcttttatac caacgataat cccgtctttt tcgtcaccgt
     9181 caagcgtgaa actgttagac tcacgaatat cattaattgt tgcaaatcgc gcatcaccga
     9241 aaatattttc tttcttctcg ttcagtttta tcaacgccgc aacagggatg ataagagaca
     9301 cgacaaatcc tgctccaagt gcaacaaagg ctaaaactct gatatccgta gtcacaacag
     9361 ataaagtaag gctgtctgta aaaatatcca tcctgtacgc atcaatggat ctgaacacag
     9421 ccttcaatgg tttcagattc tttatctggc tgaagtaaag cacaaagaaa ataaatgaac
     9481 ctgcaaacca tgccgcaaca agcataacag cgaatataaa aacagattgc gacttattaa
     9541 aagttttcac attcagcccc tttgtaatag atgtcgctca tatgcctgac aacaccatcc
     9601 ctgcctacat gaacaacaat atcaatactg tccataatga ttttacgaag aacatcaaaa
     9661 ggaagattct gacattctct gttctgataa cattttgtca ccatctgaat gatggcatct
     9721 tttgccgagg ccgcgtgaat ggacgtcatg cttccactgt gaccagaacc agcaactttc
     9781 acaaaatccc aggcatcgcc acctttaatt tccgccagta aaattctgtc aggtttcatc
     9841 ctcaaacagg atttgattaa tttcgctgct gttatgatag agccggaatc actgccggat
     9901 tccgaagggt aaaaaagatg cacataattt ttatggataa aaaatttgat ttcctctgca
     9961 tcttcaatcg taatcagccg tgtattcaat ggtatgaaat cgataagact cttcatatat
    10021 gttgttttac cggaacccgt tgctccggca aatacaatgg ttttccctgc tgctacggca
    10081 agctccataa aagcagcgat atttctcgct ctgaataaat caagaagctc atcatcgtat
    10141 gtcctgtgtt tttttcctga ctggacataa tcataaaaac cgttcgccac atattcttta
    10201 tgcgttatct gccgtgtcga tggtttacgt atggtgattg aaatagtatt tctctcacat
    10261 gcaggaggaa aaacgacctg tacacgttct cctgattcca gtgttgctga aagtaatggc
    10321 ttggtatcgc cgatttcatc tccccgaaat gatgccagcg tctgagaaaa acgtttacaa
    10381 aaatcaaagg tcacactgtc attattatgg aatgtccagt caccattaat ttccgtccag
    10441 atttcaccag gacggttgac agcaatttct gttagccctt caatatcaag aaaagactgg
    10501 aatacttgat ttttataaaa atcgagcgat ttattgctaa tgctgacagg aataacgcca
    10561 ttcatactat tttaccttta actcatagat atcagaaaaa tcaatgtctt ccccgaccat
    10621 aatagtgatt atgtcaccct ggtttttata cattgttgga ggaatattta tcgaattctc
    10681 aagtgcgact ttagccattt cagccattgc ctgtcgtgag ttttcggtat aatccacatt
    10741 acgatcttta ccaggtgcat tatccgccgc cgcagccgct acatcctgaa ccatactgag
    10801 cataagagaa ccaccaaaac gctcccagaa gtgagaatcg atccatccat caatgcccgc
    10861 ttctcccagg gggccagccg ctgctgtatt taccatatcg attcgtttat tatcaggcgt
    10921 ccgcaactgc tcccacataa cgaacattct gccctgtcca tgattcagcg ttccggtctg
    10981 gtaacgacca aaagccttag ttccctgttc cagtaatttt gtgtggtgat tagcactcca
    11041 tacatcttct gtaaaaacac aactgatacg acctgcaaca tcagaaacaa agcgtgtggt
    11101 taaagcacac ggtataagcc tgttttcctc aatatagaga tcaggatcga gattaatcgc
    11161 agttactttc attcctgatt taccaggcac attttctttt gattctttcc tttcttcctg
    11221 tggctctgat gtcctgctgc tgccactcgc gccagtctga ctccctccct gaccagcaac
    11281 aggtattgac aaatatttcc tgaacccctc ctgtggcact tctttatgac cgtcagaaac
    11341 agtattacca gaaccagtag cgcctggatt gataattgct ttgttctcaa cagggtcaaa
    11401 attctgacca agaccagtac ggattttact tacctgagaa atgctggtat cgcctgttga
    11461 ttctgatgct ttctgctggt catctgcaaa ataattttta tatgttttca gcgcaaaaat
    11521 accaataact aatacagcca tcagaccaaa cagaaagcca gaacgcatac gattattttt
    11581 gttcctgata tcaccgatat catgaacggg tttactttcc agctttgact gattcgcatc
    11641 atcaactaaa tcatctgttt ttttcatatc agtcattatt cacctcaaca cgttctaccg
    11701 caggagaaga tgtattcctc tggtcggtta atacttttcc gaaagattta ttcacaacac
    11761 caacaacgct gtttccatag cgtaaaacaa atttatcatt aacgttgtgg ataaccataa
    11821 ttttatactt gccttttgtt tccacattaa aagcaagtgt ctgttcctga ccatctctta
    11881 cagcaaatgg agctgggaat gctttccctg agttaaaacc taaaaaggta aagataccat
    11941 tatcataagc aaaatcaggg gcgatacgac ggctgtcata tttttcattg actcgcatga
    12001 aataattcca gtttttaggc gcatcggctt tttcaaaact ttcagaaatc agtttcttct
    12061 gtctgagttt ttcctgtttt tcttttgcca gccttacttc ttctgcattc tttttcgcta
    12121 tttctgatgg atagcggaat tgtacaacat aagcaggttg cgcttgtttt tcttctgaca
    12181 gaaggattag atccagactg taaatccgct ttgttgttct gacaaaaaga ttcgtatccc
    12241 attccttttc tgttggctgg aaaacctttt tcagtttttc gccttcatcg ccttcctgtt
    12301 cctgaacaac gggacgcgga ttgatgtaaa caacattatc atcagttgtg atttcccatc
    12361 cggcaggaaa accagccttt gcactgataa cagcctcacc ttcatcgaaa acaactgatg
    12421 tgagaaatcc tgtctttgac cggataacgg tcgtattcgc accgttataa ctcacagtct
    12481 gcatccttgc atcaaatcca gaaggtaacg gagtcgctgc tgaatacaca agcccaggaa
    12541 gcaataaaca tgtagcaata aataatttct tcatcattcc cccctggctt cccgatctgt
    12601 ctggtaactg gttacagtaa aaccgagagg attaagctca cgactggaac ttttaaccga
    12661 cttttctggt tcaaaacgat atgtcacacg agccgtccag tatgaaactg aaacctgtcc
    12721 ggtcgtgaag tttctcgtcg tttttttaaa gcgcacagag gccagtttat ctggcgcggt
    12781 tgcgtcagaa ataatattgg agatgacctc aaccgcaacg taagaaccat tattatgata
    12841 aattttatca ggagccatat cgctgttata cagacgaaga taatcgtcct ttactgtatt
    12901 cgaactatat agctgtacag tctcataatc atactgaaga gacggataat tataaccttc
    12961 acgtaaggta atatacgtgt ttacaaaata ccgccctagt gcttcagatt gcaggatctt
    13021 ttcctgttta acctgagtaa tcagttctgt acggcctgtt ttttcgccaa cagccacaat
    13081 agcaagctct ttttctttta atggcacaag aacacaaatt gcagccccaa gacataagga
    13141 cagtaatgat gctgccactg caacacgcca tgcatttttc ttagaccgtt cattttctgc
    13201 atagagttgt ctttcgaagg atttagctgt ctcaatcttc ttttcgattt tttcactcat
    13261 aactgattac ctggctgtgg ttaatgggtt ccagttcgcc ggaaacatca gaaggaaggg
    13321 tattccttgt ggtacatccg gaaatctgaa acaggaaaaa caaaagaatc acacatcgca
    13381 taaattcacc ttattaagcg ttcacgaaca ccttgaagag ataaaggcca agatgaagaa
    13441 aaagaatccc accaataaga agcaaaaagc gaagatccat accctttctc catttccccg
    13501 caagccctaa accaagtctt attcctgcga agcaggtaaa cactcctaaa agaaggatta
    13561 ggacaaaata aagtatcatg acaaaataat gaagcatgtc acaaccagct ctgactgatt
    13621 ccacctaaga ccttaaataa ggtaattccc gtgattaaaa taataagctg ggttattagc
    13681 tttctcttcc tgctccatcc ggaggtgata tgtttatcaa caaacgtcag tatccagttc
    13741 agggacatca cataaaaaaa acgtttcatt atattcatgc ggcattcctc gctcgtgctt
    13801 tttccaggga tgcaagtctt ctcgccttca tccccaaagc acctgtcgga gccagcgcct
    13861 gatatccctt ttcacccgcc cattcagcgg ctgttctcgc accacgcccc atcagattcc
    13921 ctgctttccc tgataaagaa ttcatgcccg ttcttccggc catccctaag ccaaaaccta
    13981 aaccagcacg accgccaagc atcagagact taccagtagc catacccgca gcacccagcc
    14041 ccatcatggc tgcgccctga acagcacctt caacacctgc acctgctaac tggacagcaa
    14101 aacctttagc tataagaacc aataaagccc ccaaaaaacc agccataaag cccatagcac
    14161 ctgtagatac aagatttaca ttccctgttt gtgcagcacg aatagcatgg gaaaggatca
    14221 tcccttgaaa atccattgct atccgaatca ctaaactggc aaatagaact gtcagaatac
    14281 tggagaataa cgattgtaac caattattaa acatgctccg aataaaacca aacatgagac
    14341 aaaagataaa tatcggtgct gtaataatca ggagtttcat cgttacatct gctgttaaaa
    14401 aaacaaccac actaacagcc attaaaataa gcgagccagt ccatattaaa aactgtccaa
    14461 ctacaccttg atctttaaca tatgttgatt tatctaaaga gtatatttcc gcaccaagat
    14521 tttgcgtact tttccataag ttatctaaag tttgccagac actcacccct ccagaaaaac
    14581 catctttcat gccttgcaac gcatcagtag ccgcagttaa atacccatcc gcattagtta
    14641 taaacatgat tatgattgca aattttgata gatcccatac taaatcctgc aagggcgtct
    14701 gagttttact ggcaagtatt tgatatcctt tccatagtac atataacgta accgataccg
    14761 tcactaacga cataatatca ttagcaaatt gtgtttgata actggagctg attttatcta
    14821 ccgaatccat aacggtagaa ttatatttaa cgaaaaaacc ctgagccata tatccacctt
    14881 ttaatcaaaa gttaatggtt cagcttcttt ctgctgttta ataaaggcct cttgttcatg
    14941 tgtgagcaac atctcatgat ctgctttatt tttattattc cagacatcat actgcatttt
    15001 tatcgcctgc atttttaacg actgcgcctg taatgcgtta gccaaatcct gggattcttt
    15061 gatatccttt gaagcctcaa ttcggctact taaactctga atctgagaca ttgcacttga
    15121 taactgctta ttgatctcat ttccctgttc aatactggca gccgttgaca caatccgtgc
    15181 tttacagaga ttatcattac gttcatagcc cgtattacac atatcaaagg ctccatactt
    15241 gctgaacaga tttttagcct ggctgcttaa tgcaccttcg ggattactgg taaaatcaga
    15301 aatataactg ttcccctgct tataaatatt tgtcagttct gattgcagat tacttagttc
    15361 atttgtgaat gccgcaatat tccttatacc tgttgccgtg gctaactggt ctttatatgc
    15421 ctgaatctga ccctgataat gtttcgcagt ttcggaccat tgtttgagtc gttctgtcca
    15481 tcttgcggct tcaacagccc attccggact ggcatctaca gcaaccggaa tacctgcgct
    15541 gctataaaat gaagccgtca ataatgatat cagcataaat gtttttacac gtttcataaa
    15601 ttcacctgtc agattgcccg ttcgagatat tcaggaaccc agtcatcagg ctccattcct
    15661 tcatgataaa tactttcaaa aatttccaga ttatctgcac tggcagacaa tattttcaga
    15721 tatccaccaa gtcccgataa atcgagtgtc gcaagtgctg aaaatgattt accatccccc
    15781 tttttaagac tgcttttttt aatcaggaac tgtctcgaca ttggatcaag atttttaata
    15841 atattaaatt cttctggtgt cagcttaagc ccttccacat aatcattgta atcggcatca
    15901 gggttagcca gataaatact ggtgctgcat acttcaacca cagcccgtga aatcttattc
    15961 ttcagtattt catccggaga ctgagttgcc ggaataacca gcccgttcag cttacgaatt
    16021 gttttcagct tgttatagac aaaatcgctg aatgcttcat cctgtagcca tttccagaac
    16081 tcatccagga aaataacaag acgccgaccg tccagaagct gcgtaatgcg atacagcaga
    16141 tagaaagtaa ttggtgcaca taccatcgga tcatcaagaa actcggtgcc atcaatgcca
    16201 aaattattga catgctgaat attgaatgtg tctttagcat tatcaaaaac ccagccatga
    16261 gcctgactat tagcccattg ggacaaacga aggataatcc cgttctcctg ctcatcccga
    16321 tcatctctct gcataagatg ctcaagcatt ctggtaatgc catattcccg catttcgcca
    16381 ggaggaaaat ccatcacagc atcaacactt tcgctaataa gcaatctttc tcttgtcgat
    16441 aatctttcac catttctggt acacagaatc tccatcagtt gcttcacaaa aatacggtta
    16501 cgttttgttg cctccagagc aaaaggattc catcctgtcg gctcaccgct ttttacggtg
    16561 taatattccc caccaagcat tcggatacat aattcagccc ctctgtcctt atcaagaaag
    16621 acacacgtta acttcttatt ttttgcagaa tcagcaaaag tttcggggtt attgtatttc
    16681 tgtaatgaac aggcaagata tgacagaaac attgtcttac ctgaacccgc cgttcctata
    16741 actttagtat tagcaagatt cttttcacct gtttcatctt taaacagtac tgagttatgt
    16801 aaattcagat aatacgcctg tttgcttggt gttttgagaa tagcaaccgc ttctgtccag
    16861 cagtttttat cgcgtttccc ctggtagaaa ttatggaatg atgccagttc gacaaaattt
    16921 acattcgata ccggagataa acgcggcctt aaatgaaaaa ccgccggaag ttgggcaaaa
    16981 tatgccgctg gcaatgacat ggttgacaat gccggaataa tgcccaggtc agtaaagtct
    17041 gccgtaattt tacttacaga ttcgtcaagc tccctgatac tgtccgccat taccattatc
    17101 gtgaaatggt agtaaccaaa ggatatatca ccggacacaa tatcattttt tgccttttcc
    17161 agttcctgca attgagtgac cgcatcatct tctgtactct ttaactgttt ttccgcacgt
    17221 ttaatggtac tcaatgcttc tgatttgctc atggatgtat atgaatgcgt aataatatag
    17281 tcagcatcag aatactggag cacatcaaaa acaccggatg cagtctcact acagaaatct
    17341 ttaatttcaa tagaacgaaa gaatttattt ccatcaatgc ggcatatctg tccggtatca
    17401 tgattaaaaa atacatccac tccaccaaga acgttataca ccggagaatc agtgactctg
    17461 attttttgca acttccctgt cagaagataa ttatagaatg acagttgaga agaaaatacc
    17521 tttccgttct cctcatacat accaagaagt ttacaggtaa atttatcaag agcgccagag
    17581 aatgtattaa tcatttcatt cattctcttc acatgaatgt gaatatcatc tttcttttct
    17641 ttaatacttt ttttgcgttt ttccagtttt tctacacgcc cgtctggtct gtagatcagc
    17701 gtaaagtaaa gagtgttccc cttgaattta tttttcttca tcgaaccata ataacaatct
    17761 gatattatat cagcatattt attacctgat tttgtggtaa aggcatcata aaaactcgcc
    17821 ctgcatgaat ggttataaaa tgaaacgggc agtccggaaa atgaacgaac aagagtggca
    17881 acctgtgagt caatagtttc taacatctcc gcagagattg actcaaagtt aatccccatc
    17941 agttgccatg tcgctacata atcaccgttc tttgttttga caatattttt atcaacatgg
    18001 cttgaatagg gtatatattt accagtagtg attcgctcat tcagtttcat ggcattaaca
    18061 aactcatcaa tttcaacagc ttcatattgt ccggagagga acgctcgtgc gccaaaaaaa
    18121 cgattacaca ctgagtttcc gagcattttc agcttaagaa agtaaagatt aaaaatgtgg
    18181 tcgtcctgct tagttatcat tctgagaata aaaactgcga caggaatagc cagccagatc
    18241 agcttgctga tataaacccc cgccagaaat aacgcccctg caaccacagt aagagggacg
    18301 acaggaacac ccacatacat agcagggcgt gtcatcgctt tataaagtgt agacatacta
    18361 tcgtccccgc tttattagtt aaccatcatt gatgcaactt cagccgcact ggcgataaca
    18421 attgccccga tgatgatagg tgagcattca cgaatcgtgc ttccaccaaa cagaaccttg
    18481 tagccgaccc acagacaggc aatagtcacc gttaccagtg aaaggccacc aagccctgtt
    18541 ttgacctttt gcagcagtgt ttccgctttt gaaaatccat ccgcaaaggc cggtgatgcg
    18601 actgttgccc cggcgactgc cataactacc ttatttttac gctgcattac agcagtgaca
    18661 gatgaactga tacaattaca tactgatttc ttaaatgaca ttttataagt cctgttaatt
    18721 aataactttt gttggatgtg agttatcaac aaaagcagat ttcagaatgg tttcgggcca
    18781 gataactgac gcattgtgtg aacgattttt tcgctgttct cctccgttgc ttcttgtacc
    18841 tggtacaaca tatttttttt cgttccctgt ataaccaatt cgctcaacat aacttgtatt
    18901 attaaattct ttttcttttc gcttaccgtt actaaaattt cctgtatagt aacaactaag
    18961 cgcattctcc aggctcctcc ctcgtttata acaatccacg ataatctttt cgaaaacaga
    19021 caagttttca cacgaatcaa ggagtttttc tgcggacgtg gaataaaaag aaaaattact
    19081 gctggtaatc tgcatcaatc cgacagaata acgtcttttt ctgttttcaa tttctctgat
    19141 aactgttaga gcttcctcct tacttttggg catatgactg ataacacttt tgccatagct
    19201 accgcgttcc ctttcaggaa taatttcagc cacagcataa ggattgaagc cactctcgac
    19261 ccgtgcaata tcatttatcg tatccggatg aactgacgcc gcacacagca acaaggctgg
    19321 gaataaagac gccatagcta acgctccata tatccatcaa tacgcatact ctgcattaat
    19381 aagtaaataa tttgcttcct cttactaagc aaagatgttt tcgttttctc ttcgataaat
    19441 gcattcaacc tgggatcgag ttttatcgtg acataaaccc ctttttccga tgacttatct
    19501 ggtttctcct tcatttaatc aatccactat aagtgtgttt tggatttgtt ttagatgcga
    19561 acatgattcg caaaataaca attctcaaca atacgatcaa ataacattga caaaatggtc
    19621 atattatgat tcgtgtgatc atgcaaaaaa aaagcgccca tatgggcgct ttagtatgat
    19681 ttaaacatta gttaatcgaa tgtagggact ggagcatcct tctgagactg aataaacaat
    19741 gcttgtttaa cattcttaca gttctgagaa tcagagccag acttctcaca ctctgcctgc
    19801 ttttgtttag cttccgtaag atgctgcccc caccaatcca cactttttac ttcttcacta
    19861 caaccaacaa cgaagaacgg caaagcaaaa agcagatatt ttttcataaa ttccccctct
    19921 cactgatcct ggaaagactt gacacgagaa gggcattagt ccgaatgagt accagtgttc
    19981 tgatccctgc caacgagaca cctcccagtt cagctcttac agaatcgaga tattttctga
    20041 cagttgaagg ctttagtcct ttgaaatcag caatttcatt cagggtatag ccataagcgt
    20101 acatcagaat aatgtctttt tgttgctcac tcaaatgttc ttcatcacta aaaatttgat
    20161 gaagtgcaga aatgcagata gcatcatgct cagtcatgat aacctccctc gtaggttgtt
    20221 gtgatcagca ggtgagcaaa gtagccgctt tgttcacctg cgccgaaatc aaattaaaat
    20281 cccaggcctt tccagttcct ctcttgctgt attcttagtt ttttatgttc ttctgaatcc
    20341 tttgtaaacc cgtattcaag agcaaaaccg atattgtgac cttgctcatg ttttctggat
    20401 agctgttttt taacgtcgct ctcttccggt tgcctggttt cacgctcatg aacctgacgt
    20461 tctctgttcc gctcaagggc aatattttca atctgccagt tattgcgatg cgtttccctg
    20521 tagcctgcaa cagttccatc atcattaaac atcgggctac gtacaagcgt gggagccagt
    20581 tttttaactt tgataagcgt tcctggctgg agcttttcag actcgaaatg atttttcagg
    20641 tctttacccc aaatcgtaac ctgttttcca ccttttaaag tttcataagt gaggaaaggt
    20701 gttcgttttt cccctgcctt attctgatat gaagtctccc caaaatccac aaccttgtaa
    20761 acattccgga gtcttttcgg attttcagcc tgtaatcgct caatctcccg tttacgttcg
    20821 ggatcttttt tccaggtagc agtaacatca tatcccatac ctttcagttt tctatgaaaa
    20881 ccgtttctga acttcctggt ttcagatttg gtaagtctta atcttcttcc tgtttcttca
    20941 tcacgaagtt taatattaac atgtacatga ggatgatctt ctttatcatc atggtatacg
    21001 gcaacgaaag catggtttgg ataagtctct ttaagaaatt ctaccgtagc tttcagagcg
    21061 tcttccctgc ttactccagc ttctggtggt ggtgaaaaga ccatgttttt cacatgatcg
    21121 atgttttctc cacgatatgt cctggagtaa tcatttcctt tagataaagt tgaagtaaac
    21181 tccctgttaa agtcttctcc tttccctgtt tgctctgaac cttttccatc ataacagtaa
    21241 gcctcaagtt caccattacg ggtaatgtaa tcaataccgt ttttgatacc tgcggctgtt
    21301 ttacctgagc cagtgatttt aaaagtgact tcttttgtag gtgtccaggt atatgctttc
    21361 ttgtccgcac catgtctgac tttatgatta aaagccgatt tactggcatg tatatgtctt
    21421 cccgataact taggagattt cggatcacgc ccagtccctt tagcgcgttt aatacggtat
    21481 tcctgttcta catacacacc cataaatcac ccaaatctgt taacaacact cttggttaac
    21541 gtttcaagtt ttgaatcaat tcgcttacac agttcaatca cttcaataac gtcttttctg
    21601 aaatctggat cgttaaccgt acagaatctt tcacctttta tgataaaatg aatgttgcga
    21661 ccaacacgat ctacagcagt tgatagtttt ttaagttcct taacttcatc agggtaaaga
    21721 cagacttcac tctttaacaa agactgacgc acacgaatag caatttctct gctcatgctc
    21781 atgccgtgaa gagcagcatt acgtttaaca agttctattt catgagggta aagacgcact
    21841 gataccagct ttgctggttc attattaact gggatgttaa caggcttggt ttcaatatta
    21901 agcacgttat gcttagcaaa agcattgata ctggtaaatc cacttaaaat agcgttatgt
    21961 tctgcaaatt ttaactcatc atcacttagc ctgaacgcta tcatcttcat aagtcacccc
    22021 aacagagcct gcggcaggca caggcaaaaa catcgttttt ggacaatctg attcaaatgt
    22081 taacatttga catcggattg tctatcctgc attgattgta ccatatgtgg cactgtgcct
    22141 agctataaaa tcgtcgctac atatgtccag atttcgttgc tgaaagattc tttcgtcttc
    22201 gaccatcagg caaacgtata gctgaaagat ttgtgaaaga aaaaacaggc ctggcagggc
    22261 tgggaattgt tacggctgaa gccgtaacgc tttttaagtc ctcgctacgc tgcggggctt
    22321 ccggcgcaaa gcgcctccca tgcccttaca gggcataaaa aaacaagggc aattaagccc
    22381 ctgcgcgatg attgctgact tctttttcca gagccttatt aacaaaggca ttcaacgata
    22441 aatcttcttc catcgccatt tctgctaccc gacgatgcag ttctggatca agcctgacgt
    22501 taaacacgcc tttaaacggg gtatcaggtt cctttccatc ctccacacaa gactgtaaat
    22561 acagatcaac agatgtttta aactcctgtt ccagttcagc taatgtagaa gcctcataag
    22621 ttaccaggtc ccgaataaac gccagttttc catacaggac attattttca aaatcgggtt
    22681 caaccgtgcc taaatatcct ttatatttta aatgtttcat aataatccag cctctttcag
    22741 attctgttta attgctttca gcgtaccacc tttgatataa ctttccggat gtggacgatg
    22801 cattaatatg gtgtgattga tttcagcatt gaaaaaccgc actcttgacc cctgcatttc
    22861 ctttttgaca tatcccaaag aggaaaacaa aacgaccagt tcatcccatt caaacgtttt
    22921 tttactgttt aaaaactttg ccagtagctt atctgttttc cccataaatc catcccctat
    22981 agatatgcaa ctaattatag ttacacatgg catttttgtc aaaaaataca aaggggcaga
    23041 aagccccttt ttttatttaa aacatttcat acccttgcaa gtagtttaac caccaccgga
    23101 attgatccca ctccgtgcac gtcattgccg gaattctggt ttcccagcct ttgacaaggg
    23161 agtcagcaag ctgtacgatc tgccgcgttg acatttaaaa acctcattca gttttgattg
    23221 tcgataacgt gatcaggttg ttccagcaac ctgatcactt tcactttcac tttttcagtt
    23281 ttcaatcctc cttagcatat ttttcattaa aatcttgtta gctgaatcaa gatcaatatc
    23341 gtacttaaaa gcaatcaatt ttattgcttt cttttttaga agttttttta attcaggtgt
    23401 tgagcatagt tctttgtaaa cctgatgaag atatacccca tgttcatctt caaacttctt
    23461 gtcaataact gatgtataca ttatagcgtc gaaacaataa tcatcatcta caggacaagc
    23521 aggccagaac atcatctcta ctgccatttt tttagcttca gtaagcatat ccgattccgt
    23581 gatcattttc tgtttatatc tccgctgaca gtggttacgt caccagaaac atctccacaa
    23641 gtaacatcac cgcttacagt ggttatatcg ccattaacct gatgacaatc aacatcacca
    23701 ctcacggttt caacatcccc ggcattccca tgaatactga catcagcatt ttcggttact
    23761 attttattta catttccatg tatttctacc ttaatactcc tgcctttaaa aaccactgtt
    23821 ttattaccaa ttttaataca atcatcagtg acaacaatgt tttcactatt ttctaccgag
    23881 acatgctctt ttccatcgat ggtaatttta ttaccggcaa cgattaaacc tttaccaaca
    23941 acataaacac ttttcataaa atcaactcct ttcaggaaaa tgcagggatg cccctgcatt
    24001 cataatgctt aacgaaggca ctcaataaaa tctttaaaac ttaagcattc atcgccatct
    24061 tttaacgaat caaaatattt ttcatattcg tccctgtaga aaaggactaa atcaacatca
    24121 ctctgcttaa gttcgccaaa ctgaggaaca attccggttt tatagtcacg aattttattg
    24181 ttatcagtaa atatgacaac atactgttgt cccgtatcct tatgcataag gataatagtg
    24241 caaagcgtta ctcgttcgaa cgtgaaaaca tgattagtgg ttgaagtaaa aacagatgag
    24301 catttcattt taaatctcct gccctgttgg gctattgtga gaggggccat tcccctttcg
    24361 atgaaataac aatacgactt ttaagtcgta tttgcaagtt ttctcccgtt tttttactcg
    24421 ataagtgatt gttatcacgt tttttaatcc gcgtaagcgg atggaagggg cgaacgaaaa
    24481 tacctgggca gcacaggagc cacatcgccc cgaagcgcgg cgcagccgct gacgaacgta
    24541 ccagggtgca caggccatcc cttcaccctg caaagcccaa ctgaccagca ggccatgatt
    24601 atgctgattt gcgccgcaga atgccgcagt tagcgcgagc gcaagcgagt ttaccccgcc
    24661 ctggtgcatt gcagcatggc ggggcgctgt actgcgcgtg tgagcgtcag cgagctacgg
    24721 gcgcaactcc aggtactaat ataaaaccat cataggtcat tttattttga ctcccttttg
    24781 cagagcacgt attcaggatg ttctcctgca agtaacaaaa gaaactcaaa ctcaaccagt
    24841 gacagacttt gactgttttg agtattaact tcctcttttt tctgccaggt tcttagccca
    24901 acaccataaa tatgactgca ttccttttgt gttaatcctg cttttaaacg taattttttt
    24961 acattttcag gtgtattatc aggtttcatt taacataaac tccttaatta aatttttaac
    25021 tggcgtctca tcgtcttccc ttaatccggc acacgtaaaa tcaatatgtt gtaattcatt
    25081 ctcattcagt acggcatcat acaatgtaat tttcgtagtt ttgttcccga ttttaacatt
    25141 tgttctggct tttatccttt ttgtaagcct gtaattgtca ccttcttttt caagaaaata
    25201 agtcacatcg cctttatttt ttctcataac tgtttcaaat accctgtaat tttaacaagt
    25261 tgatctatac tcaagccccg aatctgtaaa tcataactgt cgccctgttc ggtgacttta
    25321 ccgttcaatc cgttttcagc tttaaagcct gtcaatgccc cataccagct ttcaagctgg
    25381 acaagttgcg ataacatacc tttcaggatc agaatttcgt cctttttttc cacctggtgt
    25441 ttctcatact caatcgcctg taacacctcc tgcgaagcat ttaccagaat ttttcgctcg
    25501 atatcggctg caatatcaac gggattccgt tttctggata acgtgcaaac atgatgcgga
    25561 ctacgccagg agcgactatc cacactcccc acaacagaaa accggtcttt ttccatccga
    25621 atatgcacag agtaattttt aaactgcggt gacgtcagtt ttatacgaga cgaacaatca
    25681 tcaagtttgt tcacgcgcca gccgttcccc aggatacggc agacaacttc aaagacaggg
    25741 tgatattgtt caaaaaaaga gttcatctgt ttcccttttt gctacgtagc tgctgttccc
    25801 gtctttttgg gttcgatgcc ccaaaagacg ggctggctat aatatcgggg gcttctcgcc
    25861 cccgttctgg ttacgctctg gtttccacgc gttgccaccc tgtcgccctg cgctgtccgg
    25921 ttgtaccgta ttttgcgcgg atttcttcta tcgtgtgttc ttcacgattc cagtaacttt
    25981 tatgttcgtc tggacgataa aaccattgtt ttttctttgc cgcccattta cacccgattt
    26041 cttttaaagt ttccttatgt gtaatggttt ctccactaat ccagacccag ttacctatca
    26101 cttcaaatac cagaccagat aaaccagaaa gaacgtttaa tactttttcc aggtcatcac
    26161 cgtaattata tcgtgcatgt tcatcagtgc tctggaactg atttatttta tcaatatttg
    26221 ccatcaatac atcaaaagct gcatttaccg ctttcatcag ttcagcccct aacgggttac
    26281 gatctggatg atattttaaa gcggcttttc tgtatgctgc tttgatatct ttttcagtta
    26341 attcgccgga taatccaaaa acgtttaatg cttcctggat attcattttt ttaatctcct
    26401 gccctgttgg gctattgtga gaggggccat tcccctttcg atgaaataac aatacgactt
    26461 ttaagtcgta tttgcaagtt ttcttccgtt tttttactcg ataagtgatt gttatcacgt
    26521 tttttaatcc gcgtaagcgg atggaagggg cgaacgaaaa tacctgggca gcacaggagc
    26581 cacatcgccc cgaagcgcgg cgcagccgct gacgaacgta ccagggtgca caggccatcc
    26641 cttcaccctg caaagcccaa ctgaccagca ggccatgatt atgctgattt gcgccgcaga
    26701 atgccgcagt tagcgcgagc gccagcgagt ttaccccgcc ctggtgcatt gcagcatggc
    26761 ggggcgctgt actgcgcgtg tgagcgtcag cgaactacgg gcgcaacgcg ccagaatctg
    26821 ctctatgtta atgctaatgt atgcatacat tagcattaac acacgcatct atcacatcgt
    26881 ctttaaatgt gtattaatac acaccgttaa actattgcca gtacgcaatt gtacgatttg
    26941 ccgattaaat accggtgaac gtcgggcggg ataactgcgg ttttgatggc atggaaattc
    27001 ccccgcttag ggggaactgg agagattagt ggctggattt actgagagtg aact
//
