LOCUS       NZ_CP026728            33288 bp    DNA     circular CON 16-JUN-2024
DEFINITION  Escherichia coli strain 266917_2 plasmid p266917_2_05, complete
            sequence.
ACCESSION   NZ_CP026728
VERSION     NZ_CP026728.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN08498861
            Assembly: GCF_002946715.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 33288)
  AUTHORS   Greig,D.R., Doumith,M., Hopkins,K.L., Woodford,N., Dallman,T.J. and
            Jenkins,C.
  TITLE     MinION nanopore sequencing identifies the position and structure of
            bacterial antibiotic resistance determinants in a multidrug
            resistant strain of enteroaggregative Escherichia coli
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 33288)
  AUTHORS   Greig,D.R.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-FEB-2018) Gastrointestinal Bacteria Reference Unit,
            Public Health England, 61 Colindale Avenue, London NW9 5EQ, United
            Kingdom
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 11-OCT-2017
            Assembly Method                   :: Unicycler v. 0.4.2
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 311.0x
            Sequencing Technology :: Nanopore (MinION); Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002946715.1-RS_2024_06_15
            Annotation Date                   :: 06/15/2024 03:05:49
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,895
            CDSs (total)                      :: 5,762
            Genes (coding)                    :: 5,478
            CDSs (with protein)               :: 5,478
            Genes (RNA)                       :: 133
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 100
            ncRNAs                            :: 11
            Pseudo Genes (total)              :: 284
            CDSs (without protein)            :: 284
            Pseudo Genes (ambiguous residues) :: 0 of 284
            Pseudo Genes (frameshifted)       :: 100 of 284
            Pseudo Genes (incomplete)         :: 210 of 284
            Pseudo Genes (internal stop)      :: 60 of 284
            Pseudo Genes (multiple problems)  :: 69 of 284
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP026728.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..33288
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="266917_2"
                     /serotype="O51:H30"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /plasmid="p266917_2_05"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2016-06-08"
     gene            14..517
                     /gene="ddp1"
                     /locus_tag="C4R22_RS31085"
     CDS             14..517
                     /gene="ddp1"
                     /locus_tag="C4R22_RS31085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000781813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA distortion polypeptide 1"
                     /protein_id="WP_024190319.1"
                     /translation="MKMIAFRLSDDELKLAEHNAISSGFTSINIFARHNVLNVDVQPSN
                     IPVSNESSKAVKTCLYPHEIELVKRNAALHGMSMSREIAIRVRQSLLKNEVCLYPDEVK
                     ELKKLSTAVDRVGRNIHFIIKGERFCTVNDPDFRKDVIEVIELCKQIDSKLETLTKSVV
                     NRFG"
                     /name="ddp1"
     gene            521..1750
                     /gene="taxC"
                     /locus_tag="C4R22_RS31090"
     CDS             521..1750
                     /gene="taxC"
                     /locus_tag="C4R22_RS31090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001329504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA relaxase/nickase TaxC"
                     /protein_id="WP_001541982.1"
                     /translation="MGVYVEQEYRIKRAKGTGRDPKSPKLSGRHIHASKSAFNHKVRHG
                     ADKKAYTWTPTKEVTFKITGSGKTAAGIKNGIDYITRNGELEAYCYDGKGSEQTGKGED
                     FNREFTSTLSKGNDYSRTYRGENIDHVKNMVFSPPPEAGVSREDALKATVEFLKETYPN
                     HAFVAVYHDDKEDHPHVHVNIKLRDEETGRRLRLTKSETRKFRNGFHRKLKGMGYDVTA
                     TWKKDPERKREIERLQAENPKRLRNVYKVVDFGETSYQNKAGEKRTPFLTYETLKGGKQ
                     VTIWGKDLKNHFESEKLQPGTLIKVRKLAPTLVRSPMFNDDGTVAGYRETHRNNWQIEN
                     IALERNRERQVHECETRQPEESDVKKQLSRKHEQGHNIGFALEHGFTKDSEEHKKLRIQ
                     QERNWKGLGF"
                     /name="taxC"
     gene            1827..2120
                     /locus_tag="C4R22_RS31095"
     CDS             1827..2120
                     /locus_tag="C4R22_RS31095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134733.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]; GO:0016987 - sigma factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]; GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-like helix-turn-helix DNA-binding
                     protein"
                     /protein_id="WP_000134733.1"
                     /translation="MTEHDAICISALHQIFSDEEHLSEQQKDIILMYAYGYTLNEIADF
                     KGLKPSTVRKYLDSVRAELGGVSLAGIRTLVLIRTNALLVSSLSRISERGNL"
                     /name="sigma factor-like helix-turn-helix DNA-binding
                     protein"
     gene            2117..2332
                     /locus_tag="C4R22_RS31100"
     CDS             2117..2332
                     /locus_tag="C4R22_RS31100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EexN family lipoprotein"
                     /protein_id="WP_000760375.1"
                     /translation="MKKYLLFALPFFVVGCSEEVKSVDWWGQHLTEAKQKQAECEKSGS
                     DSQNCKNVKQALFIQSQKDAPVPTFD"
                     /name="EexN family lipoprotein"
     gene            2509..2685
                     /locus_tag="C4R22_RS31980"
     CDS             2509..2685
                     /locus_tag="C4R22_RS31980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000660496.1"
                     /translation="MKEKPDKSSEKGVYVTIKLDPRLNAFIEEKTKTSLLSKRKQIIYL
                     LMQSMRIDGYMER"
                     /name="hypothetical protein"
     gene            2688..3308
                     /locus_tag="C4R22_RS31105"
     CDS             2688..3308
                     /locus_tag="C4R22_RS31105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012908959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing protein"
                     /protein_id="WP_000157548.1"
                     /translation="MASLFPALLLCAASVHPDTINDIARVESGFNPYAVAEIIPERERG
                     SYGKSVISHMPKSKEEALTVIREIENRKRRYSVGLMQITSSNFSFYSTSAEKLLDPCEN
                     LSVFEKIIVDCYKRGRSLENALSCYYTGNFSNGKRKEKEFNNTSYVERIGYTGNEKKYV
                     VPGTRSNGGEQRKNRSHNASVIWPETILKSAFVDNSHPTKVIN"
                     /name="lytic transglycosylase domain-containing protein"
     gene            3322..3648
                     /locus_tag="C4R22_RS31110"
     CDS             3322..3648
                     /locus_tag="C4R22_RS31110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbC/VirB2 family protein"
                     /protein_id="WP_000008647.1"
                     /translation="MSFKKSVCNRISSSVTAVMQRKNKVVMAVAGATVASPAFADGFSK
                     AETLLEKVKTGLSGLSLVTVTIACLWVGYKVLFGGSTIRECSPIIIGAIVIASAAEVAS
                     MMVN"
                     /name="TrbC/VirB2 family protein"
     gene            3667..6414
                     /locus_tag="C4R22_RS31115"
     CDS             3667..6414
                     /locus_tag="C4R22_RS31115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231857.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB4 family type IV secretion/conjugal transfer
                     ATPase"
                     /protein_id="WP_001541983.1"
                     /translation="MSTLYKAMTRPAMYVGVPVVPLTVVAGALFLAGVYISKLIWLAIP
                     VAVFILRMITKQDDHIFNLYFLKLKMLGNSVCNRFFGARAFLSGQYEAVEIDEFVNAMK
                     LNERITTGKYIPYSSHVDKNIVKTKNGDYVATWQLMGINFESISAEMLETIDSQVATLV
                     RSFSGLPVSFYNHSCRASFYDAFTTKSGNKYADIISDCYYGSMKKNKFKGNTLYFTLIY
                     RPDGRVEKLEKRKKSIKEKKDDINIHVKRMNEMINTFSGALDKFTCKLLGMYEENGKVF
                     SSQLSFYNYLLTGKLQKIRVTDSPVYNVLGGVDVFFNHDTGQICRIDGNKFFRSIEIKD
                     FCSETASGVFDVLQYSDADYIITHSYTSMSKSEALSTIKRAEKQLKSTEDDAVTQLQEL
                     EKAKNDIVSGDISFGYYHFTLMVMADSIRELDESVSKITADFTDLGIIPALSTMSLPAA
                     YFAQLPAVFHLRPRLSPVSNVNFVELASFHNFYQGKRDKNCWTEAVAILKTPSKQAYYL
                     NLHNSVLFKDETGEKNLANTKVIGTAGSGKTMFLSYLACSLQKYNNPETFADSAKNKKL
                     TCVFLDKDRGAELCIRMLGGEYYTVKSGEPTGWNPFALEATKRNRIFVKQLMEILCTRN
                     GERLSTRERLLISESVDAVMDFPPGEMREYGITRMLEHLMQRDDRDEQENGIILRLSQW
                     ANGQAHGWVFDNAKDTFNIQHVNNFGIDGTEFLDDPMVCAPITFYLLYRITQLLDGRRL
                     VIFLDEFWKWLQDEAFSDFVYNKLKTIRKLNGLVIPATQSPDEILKNKISRAVVEVCST
                     SIYLANPDADYNDYVEGLKLTPEEFNIVKNLDPMSRQFLIKKSSLKKGDGKSFSALATL
                     DLSGLGGYLKILSASADNLEIFESIYHEGMEPDDWVPEYLERAI"
                     /name="VirB4 family type IV secretion/conjugal transfer
                     ATPase"
     gene            6426..7142
                     /locus_tag="C4R22_RS31120"
     CDS             6426..7142
                     /locus_tag="C4R22_RS31120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_001541984.1"
                     /translation="MKRVKTFMLISLLTASFYSSAGIPVAVDASPEWAVEAARWTERLK
                     QWSETAQHYQSQIQAYKDQLATATGIRNIAAFTNELSNLQSELTNIYKQGNSYISDFTS
                     NPEGALSSQAKNLFSKYGAFDMCNTGYERNDNLCKARIVSTAASIEQGNEINKQLSSAM
                     SQIQSLSSRIEASKDIKESQDLANALQAQSLKMQAIKMQYDVWNNKNKADHEMLITQEQ
                     EAFIKQQKEAEPLTFD"
                     /name="type IV secretion system protein"
     gene            7154..8248
                     /locus_tag="C4R22_RS31125"
     CDS             7154..8248
                     /locus_tag="C4R22_RS31125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001677777.1"
                     /GO_process="GO:0030255 - protein secretion by the type IV
                     secretion system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_000046889.1"
                     /translation="MAQGFFVKYNSTVMDSVDKISSSYQTQFANDIMSLATVSVTLYVL
                     WKGYQILASKTQTPLQDLVWDLSKFAIIIMFITNADGYLTAATDALQGMKDGFSGGVSV
                     WQTLDNLWKSTQNLGAEIYSLDKSTYVKDQGVVGQFLIWTGSLILMAVSVVVFLTADVT
                     MKLLIITAPIFIFCLMFGFIRSMFNNWLQSLFSSILTVLFASLVIRIAMDFQGMILSHA
                     IRAAQTGNVNLVSTGAMGFMAGFLGALLVLIAKGFAVQLAGAGVEGAVQGAAMMGLGAA
                     GMATGKSLMLGGRAGLGFGLGMAGRTGMNSLSGKAGNLMGRGARTAAEWAGEKGYQALA
                     PTGALGMKARRLASLEKARARNAA"
                     /name="type IV secretion system protein"
     gene            8763..9449
                     /locus_tag="C4R22_RS31145"
     CDS             8763..9449
                     /locus_tag="C4R22_RS31145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_001401676.1"
                     /translation="MSEKIEKKIETAKSFERQLYAENERSKKNAWRVAAAASLLSLCLG
                     AAICVLVPLKEKELAIVSVGEKTGRTELITQVKQEKILQSEALGRYFVNTYITLREGYN
                     YPSLQYDYETVQLYSSNTVKDDYLRLYNSDMAPDKIYHNNGSYVAVEVISNIISDATAP
                     DKLASVRFKKTTRNFTTGQVSVSYWTARVTYRFEPEKSVKSSSRELNPLGFTVTSYQTD
                     REVRGE"
                     /name="type IV secretion system protein"
     gene            9446..10354
                     /gene="virB9"
                     /locus_tag="C4R22_RS31150"
     CDS             9446..10354
                     /gene="virB9"
                     /locus_tag="C4R22_RS31150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001299943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type conjugative transfer protein VirB9"
                     /protein_id="WP_001353735.1"
                     /translation="MMKKLFIATCLLLPGLVYSAATPLPSGFDARMQTVSYNGANTTVI
                     RSKTGFLTSVVFDEGEAVISAKAGFPAGWEITTDDNVVYINPRPVVQEQEGDEGEKLKK
                     VFQPTEKEWDTNLFVRTTKRIYSLDLILLSEEKQAQPAYVVQFRYPSEIAKKNAEEVRL
                     AKEKQEKLRQKKLISESFEKADAPKNWNYFMRVNEKYDSRRIAPDFAYDNGIFTFLGFN
                     SGKAFPAPFAVRDGQEQTLAFNVETKGKYKIMVIHNVNDKFVLRYGNSVVGVVNKSFGK
                     VLTDQRNTSSPAVERVEVNND"
                     /name="virB9"
     gene            10347..11465
                     /gene="virB10"
                     /locus_tag="C4R22_RS31155"
     CDS             10347..11465
                     /gene="virB10"
                     /locus_tag="C4R22_RS31155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB10/TraB/TrbI family type IV secretion system
                     protein"
                     /protein_id="WP_000131271.1"
                     /translation="MTDMKKTDDLVDDANQSKLESKPVHDIGDIRNKNNRMRSGFLFGL
                     MAVLVIGIFALKTYKNYFADDQQKASESTGDTSISQVSKIRTGLGQNFDPVENKAIINP
                     GATGSGNTVSDGHKEVPQEGFRKYLSIPVAGQGGSQTGASGSSRTSQTSEPQEERKESK
                     ENVPGKSGMKVTAINLDPDLYIEENRLIPCALTTRFVSDVAGRISCVFTEDVWSANHHT
                     KLLEQGTKAFGRYQTGTLNHGQGRMFVMWEQLRTPDNKRIDMVNTAAAGPLGEAGIDGW
                     IDSHFWERFGGSLMLSMVQDVAAAAADNAPGKDRNVDYTENSRQAMAEMAKVALENSIN
                     IPPTMYKNQGDIITIMVGEDIDFSDIYELKVK"
                     /name="virB10"
     gene            11467..12495
                     /gene="virB11"
                     /locus_tag="C4R22_RS31160"
     CDS             11467..12495
                     /gene="virB11"
                     /locus_tag="C4R22_RS31160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001401678.1"
                     /GO_component="GO:0043684 - type IV secretion system
                     complex [Evidence IEA]"
                     /GO_process="GO:0044097 - secretion by the type IV
                     secretion system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type DNA transfer ATPase VirB11"
                     /protein_id="WP_001014667.1"
                     /translation="MNGVIPVSISNKSLDFYKNQVFQSFLDIEGLTEIAVNRPGEIWTE
                     INGDWTFHNNDSVTFDFCKRFSQTLASFRGDEIGDTKPLLSATLESGERVQVVFPPACE
                     RNTISITIRKPSTRQITHKEYVANGFYDYVQSGKKHRTYDDELLDLFRARNIAAFMELA
                     VAAGKTIVFAGATGSGKTTYMKSLIDFIPLNTRLITIEDAEEIKFFIHKNYVHLFYPSE
                     SGSDSGSIITAAKLIKSCLRMKPDRILLAEIKGGDAWDFVKVAGSGHSGSMTSIHAASA
                     KDAIIQMVTKCYQNRECQNLPFDVLRKIIMDSIDIVVHVGRDGVVRHMSDIYYKGAECE
                     NF"
                     /name="virB11"
     gene            12482..14344
                     /gene="taxB"
                     /locus_tag="C4R22_RS31165"
     CDS             12482..14344
                     /gene="taxB"
                     /locus_tag="C4R22_RS31165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxosome-coupling protein TaxB"
                     /protein_id="WP_001541987.1"
                     /translation="MKTFNKSQSVFIFAVMLVAAWFAGSFIFFVLYFSQIKNLKPLKAV
                     FRSIDAYRMDIFTDSLTLSVVTTDIRVLAFVALGAGFVVSLIIPVAALIKLNEKKENIF
                     GDARFATINDIRESNSFTLDGDEKDGIIVGIKDKKIIRYVGAAFSAMGAGTRAGKGAGI
                     VITNLMKYWWSVIILDPKRECFNITSLIRKVILGHEVYKFDPFSPVTHRFNPLYYVSMG
                     TSEGFNQLENLALIIYPYKTDGADAGSYLNKTAGGVFKSYAVALWFMIKNDKAGLKTLD
                     IDPVFSMSKINQLFERAEPEHLLSFMNDIRSELRGKDKTLADIGVAGLKAFIEMEDKTK
                     AQLKSNFLNGLSPFANPNVANATDGNDFDLRQVRKKRMTIYFCISGDNARLAEKITNIF
                     FQLAIQVNLEKMPTDDPEIKHDCLFLLDEFPSIGAVDYIKSKSGLIAGYKLKLLIVYQV
                     GSQLEEIYSYAGSKTLLASAPCKIVYSASDVKDARELSEAMGTRTVTIGSKSKSRSRGG
                     TSRSESESLIERPLVTTNELLTLKFSEEILAMKGENPIRCEKAFYYLNEYFFGDFVKVA
                     PELANIFPRKKGKLVMPPQKVFENEIVAKGYLAVKDVPDLDKAA"
                     /name="taxB"
     gene            14353..14775
                     /locus_tag="C4R22_RS31170"
     CDS             14353..14775
                     /locus_tag="C4R22_RS31170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001353737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cag pathogenicity island Cag12 family protein"
                     /protein_id="WP_032150585.1"
                     /translation="MMKKLVVLLISILAGCSSPPEPTPVQFEKANEVINPSLPYVPDFH
                     GVIKSDVSGKGWVYEITSLSGVKARTPTFYYALAHADRIVVTTHDAGLWFRIRDLLKME
                     GATAVVEWRNEKSFLPEQGKIVFIKAQNEVKNDWKK"
                     /name="cag pathogenicity island Cag12 family protein"
     gene            14759..15064
                     /locus_tag="C4R22_RS31175"
     CDS             14759..15064
                     /locus_tag="C4R22_RS31175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000147044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbM/KikA/MpfK family conjugal transfer protein"
                     /protein_id="WP_000147044.1"
                     /translation="MTGKNRVVLPALLALGLISTNANASDPCASVLCLYGKAVGQGGGS
                     ECRSAEKDFFNILKKKKGSIRWSKTFDARKAFLNQCSTADPAAISKIMSKFGKVKG"
                     /name="TrbM/KikA/MpfK family conjugal transfer protein"
     gene            15070..15324
                     /locus_tag="C4R22_RS31180"
     CDS             15070..15324
                     /locus_tag="C4R22_RS31180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000415096.1"
                     /translation="MEKQTTDLLNVIKTGHSGSIAGNPAHALDDKTMNAIIHNYVATIV
                     LGKAGNCKETPLTKYCSRTMPERISVEEINEFKIYPELF"
                     /name="hypothetical protein"
     gene            15427..15735
                     /locus_tag="C4R22_RS31185"
     CDS             15427..15735
                     /locus_tag="C4R22_RS31185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000647576.1"
                     /translation="MKARSVRVAGIEIIDSVKTVAFVFTETLLFMVWFSAIVYGLYRVV
                     IVLWDDPLKPQSLMEFLNFIVELYSYVLPSLAVIAVALIAVLSICKILSAIWEGRKQ"
                     /name="hypothetical protein"
     gene            15732..16226
                     /locus_tag="C4R22_RS31190"
     CDS             15732..16226
                     /locus_tag="C4R22_RS31190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001215543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thermonuclease family protein"
                     /protein_id="WP_001215680.1"
                     /translation="MRHFLKALSFVVSLLPATLCAAEIQGKVIRVLDGDTIEIKTLPAK
                     IVVYEVPIRVRLINIDAPEKKQPFGRWSTSQLKTLVAGKQVTVSYSHKDRYGRIIGHVF
                     TTNGTDASRFMVQSGAAWVYERYNVDESLPALQREAQEQKRGLWADANPVPPWEWRYKH
                     N"
                     /name="thermonuclease family protein"
     gene            16242..16646
                     /locus_tag="C4R22_RS31195"
     CDS             16242..16646
                     /locus_tag="C4R22_RS31195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001576899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001218543.1"
                     /translation="MALSPKEKKELQQRFEKQLLPDLDMSFELNGEVYKFNFDKNESGD
                     YIDSFTQAVWGGYQDAEEWEKYGKHQETELPECPEPVEGWCDCDKCKSMIFHKEKNIYV
                     CLSCHKQTEPFLPIDWNSNDYDWLPYEDEY"
                     /name="hypothetical protein"
     gene            16752..17327
                     /locus_tag="C4R22_RS31200"
     CDS             16752..17327
                     /locus_tag="C4R22_RS31200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012908955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001199074.1"
                     /translation="MQYALVDALERKFLLDALEFGVLKDWKENPVKELPDIDESVHPFH
                     VCYGGYLLNPGVSDSDISRKIKDQTGFWLAAIDDTRMDCHSIAYYDIHTLPLILCGHQK
                     IVPFAALIKADECIISKIASYSGFAVTAFLRIKDQDIATNILNREGIFAFNGCERRFRQ
                     PVSEDNWQQAVSEERAIRCANRLIQCKG"
                     /name="hypothetical protein"
     gene            17332..19485
                     /locus_tag="C4R22_RS31205"
     CDS             17332..19485
                     /locus_tag="C4R22_RS31205"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247728.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003916 - DNA topoisomerase activity [Evidence IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="WP_001235750.1"
                     /translation="MRLFIAEKPAVANDIVKALGGNFTRHDGWFESDNAIVTNCFGHII
                     ESQPPENYNPEYKAWKVETLPLRLYPVKYQPVESAAKQVKTILELIRRGDVTEIVHAGD
                     PDDEGQLLVDEVLEYAGNTKPVKRVLINDNTLPAVKKALANLKDNRDFKGLYLKALARS
                     VADAVYGFSMTRAYTIPAKARGYQGVLSVGRVQTPVLGLIVNRTRANQNHKSSFYYTMT
                     GVFQRGADVIRANWKPGEFAPLTDRKLLDKAWADGTAASLAGKPATVEAAATDDKKTAA
                     PLPFNLVRLQQYMNKKFKMTAQKTLDITQQLREKYKAITYNRSDCSYLSDEQFSEAPQV
                     IDALKSVFPQSLDIDSSRKSKAFNSAKVTAHTAIIPTASVPDVNALSTDERNVYLAIAQ
                     HYLVQFMPEKAYQEVSVAIQCGDESFYARARKTTDSGFEAFLGAETTDEGESEDNDDSA
                     FELLCKIRTGETLTTKEVIVNEKKTTPPPLFTEASLLAALVRVADFVTDPTIKKLLKDK
                     DKDKKDEHGGIGTPATRAAILETLKKRNYITLEKGKLIPTDTGYALIDALPGIAVNPDM
                     TALWSEKQAAIENGDLTVEQFINDLYGELTGMISDVDLGEMKIEPAAPAGQFQRLDSPC
                     PSCGKHIVIRPKGYFCTGCEFKIWSEFYGKKITQAQAEKLVKSGKTDLIKGFKKKSGGT
                     YDTVLVLEDKKTGKLGFPARAKK"
                     /name="type IA DNA topoisomerase"
     gene            19482..19688
                     /gene="hha"
                     /locus_tag="C4R22_RS31210"
     CDS             19482..19688
                     /gene="hha"
                     /locus_tag="C4R22_RS31210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin expression modulator Hha"
                     /protein_id="WP_000850859.1"
                     /translation="MKTKQEWLFQLRKCTSRDTLEKVIEINRYKLPLSESEAFYSAADH
                     RRAELVMNKLYDKVPSGVWKYVH"
                     /name="hha"
     gene            19704..20168
                     /locus_tag="C4R22_RS31215"
     CDS             19704..20168
                     /locus_tag="C4R22_RS31215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293133.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0030527 - structural constituent of chromatin [Evidence
                     IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="H-NS family nucleoid-associated regulatory
                     protein"
                     /protein_id="WP_001541969.1"
                     /translation="MSELTKEDEYGIISRTMMNIRSLRVFAREVDFEQLLEMQEKLNVV
                     VEERREEAEREAAERLELEAKRQQAIEYIISLGLDPESLLAPVTADTVKTRRKAKGGVR
                     KAKYRFKDENGEIREWSGNGKRPLALQKLLDEGHFMEDFLIDKLQPGQVE"
                     /name="H-NS family nucleoid-associated regulatory protein"
     gene            20272..20928
                     /locus_tag="C4R22_RS31220"
     CDS             20272..20928
                     /locus_tag="C4R22_RS31220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001478769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000972912.1"
                     /translation="MMIKSKKVVVIFVALSSFLLAGCDSPKDANKQNFEKAINTRLEKE
                     CITISPLGMFDSKPYPVQVAVAQANRYTSQERADEINSRQFSALDVLVKADLLTVKDTL
                     VDDVIGFTKTGKKVPGREYALTDEGKKYLKSPERPDFCVGHYKVDEIVDFTEPGDAMGM
                     KITQVNYTFSPTSIAEWAKRDDVRTAFLGLESDLKEKQTKRITLVLKNDGWSAER"
                     /name="hypothetical protein"
     gene            20948..21196
                     /locus_tag="C4R22_RS31225"
     CDS             20948..21196
                     /locus_tag="C4R22_RS31225"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_162750069.1"
                     /translation="MKNPPRISPTFSRISRSAPPLMTLSKILTDIFRTANNLTHCKTTN
                     QLRAGDASIALACAILSCDRYSIFEQDFPRSGQTMPY"
                     /name="hypothetical protein"
     gene            21536..22351
                     /locus_tag="C4R22_RS31230"
     CDS             21536..22351
                     /locus_tag="C4R22_RS31230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001420728.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA];
                     GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="WP_001541970.1"
                     /translation="MSHLPASIFQISRSDAWNLTISPDAARNMRDLAAQIGAGMPKYLI
                     APEVSLLLSYIDDLNIRMYFETLWNTGARLNEALALKPADFMLTPTRQYPQPVVILKTL
                     KQRLKEAERRPGRPTTRHPPLHPDPRYRKPPEPAVRLVPVLDAGYALRMREYLATWKKR
                     IKHQPVWDITSRQTPLNWINTAVARAERDGVTFSVPVTPHTFRHSYAMHLTMSGVPPRV
                     LQSLLGHRYARSTEIYTRVFSLDVLTGSGLSFTCDPQLAKQLLGYPDAP"
                     /name="tyrosine-type recombinase/integrase"
     gene            22466..23125
                     /locus_tag="C4R22_RS31235"
     CDS             22466..23125
                     /locus_tag="C4R22_RS31235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division plane positioning ATPase MipZ"
                     /protein_id="WP_000516223.1"
                     /translation="MGKIITVAGHKGGIGKSTVLCSLCVCAIRKGKTACFLETDSQGSI
                     KDFIEERKTNERLSEIPYFECYTDIPAMARKLAARFDYVFVDTPGMKSPAFVKALSCAD
                     ILFTFIEPGAGIEINTLGRLVFDIKTAQAGVNPSMKAWIVLNKCSTNPSDSEASELRRQ
                     LNDDPDWLPVPRQRIYMRTAHKKAYNSGMGVHEYDDKRGNKARGEIELLLKETGVL"
                     /name="division plane positioning ATPase MipZ"
     gene            23218..23520
                     /locus_tag="C4R22_RS31240"
     CDS             23218..23520
                     /locus_tag="C4R22_RS31240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001096507.1"
                     /translation="MAKLPKKIDQEIKPLDLRQFVSSAAQKPASASAVTRINLTMTDDD
                     LDTAQVFQNKYGASRAEVIRAALAALRLVSAEERRRLFDDIRKNSPKAGRPTVNK"
                     /name="hypothetical protein"
     gene            23557..23784
                     /locus_tag="C4R22_RS32510"
     CDS             23557..23784
                     /locus_tag="C4R22_RS32510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000905710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001541971.1"
                     /translation="MLIKIIKSVFNFYMLCVQPLLGLFLVGYSIWSFSGDGICTADKVI
                     ACDISIYLKPAFYLLISTIVLFVGYIAWQK"
                     /name="hypothetical protein"
     gene            23894..24109
                     /locus_tag="C4R22_RS32765"
     CDS             23894..24109
                     /locus_tag="C4R22_RS32765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000399458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000399458.1"
                     /translation="MEHCIFDLGIIDYNPVITWTVPVAFFFLVVLAGIVFNIGRKSNLI
                     VFILAMLLPVTTVFIFMLLGGKIDMC"
                     /name="hypothetical protein"
     gene            complement(24416..24943)
                     /locus_tag="C4R22_RS31260"
     CDS             complement(24416..24943)
                     /locus_tag="C4R22_RS31260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001473365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2726 domain-containing protein"
                     /protein_id="WP_001541972.1"
                     /translation="MIFNRNKKRDEQQNFSVVLPSAENVFSDFIKNNPALTTNAFTAIG
                     EVDCFTKVPLLSNKESEFLGILSRNIIPDYSVFPKIRLIEFVRPHGSEEAVKDLIREVQ
                     NITCDFVLKSYDETVLAVIQFGETATVRQQKKKLIIQRVCAMTGISFFEFKNTVDMMGS
                     EDFCQFLRDDEE"
                     /name="DUF2726 domain-containing protein"
     gene            complement(25079..25483)
                     /locus_tag="C4R22_RS31265"
     CDS             complement(25079..25483)
                     /locus_tag="C4R22_RS31265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012421203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001541973.1"
                     /translation="MKDNIVDFQRIRRDLGAHSTDVANDAVYSDKKKTSRFFYLLTPVR
                     YLLAASLYLVVVIPLGILAGFRFLLQFLGGIAVMGLTIAWYMGADVSGYVVLAAWIALT
                     VCGCAEQIFEWWIESRFAFRLFGIGRTPEE"
                     /name="hypothetical protein"
     gene            complement(25549..26556)
                     /locus_tag="C4R22_RS31270"
     CDS             complement(25549..26556)
                     /locus_tag="C4R22_RS31270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243325.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_000243324.1"
                     /translation="MVLKNNKNSDCNDVQSLLAQGNQLLEGAYDITLIEMRLLYLALTK
                     IDSRKPQPANEYTLFAKEYRDTFSLDSKNCYEQLKSAASSLGSKPIVTYEWNEAKKRID
                     AVKRFWFSSIRYGVGNSESDITLRFSDSVSQYLYELKSEFTQMNLEHMVKLDTPFSFRL
                     YSWLYKYKNLNRNKKHSGVISTDPITIEWMKERTGLTGKYPVYKDFKKRVLDPAVDIIN
                     ANTNLSVTYEGIKSGRKIESVVFTYLVENETHDGKKIATKPLRPRLPSRPRVIKGSSAE
                     VAWAKKCIDVMKNYLISLREYDDKLKLSRPDLQKVKLWHEITGWDFEESFWFSD"
                     /name="replication initiation protein"
     gene            28099..28428
                     /locus_tag="C4R22_RS31275"
     CDS             28099..28428
                     /locus_tag="C4R22_RS31275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001647051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_001541974.1"
                     /translation="MFSVVYHPEAREEATALPLKIRVKFDRLIGKLEYDARLLREPDTK
                     PLGDGLFEIRTMGTDIARGIWVYHKGNTIIMLRVFIKKSQKTPVKEIDLARKRLAEVLN
                     ETGKP"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            28409..28690
                     /locus_tag="C4R22_RS31280"
     CDS             28409..28690
                     /locus_tag="C4R22_RS31280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019077272.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000780222.1"
                     /translation="MKLVSHKELHNEWMQDDEYRAAWQEEERKEKLRELLAEWRKHDNL
                     TKAQVAERMGVTPPVISRLENNITKASIDTLTRYAHACGIKKPVIALY"
                     /name="helix-turn-helix transcriptional regulator"
     gene            28705..29031
                     /locus_tag="C4R22_RS31285"
     CDS             28705..29031
                     /locus_tag="C4R22_RS31285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001541975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001541975.1"
                     /translation="MSKTDYPASVDHNAAMIEELRADPDYANAYLANALEEINEPGGLG
                     GFLVALRQVIEARGGISEAARKSGLARQSIYRALSPNGNPTITTLAQLTSVAGLQFTLS
                     KSSH"
                     /name="hypothetical protein"
     gene            29375..29607
                     /locus_tag="C4R22_RS32770"
                     /pseudo=""
     CDS             29375..29607
                     /locus_tag="C4R22_RS32770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001744154.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            29671..30186
                     /locus_tag="C4R22_RS31295"
     CDS             29671..30186
                     /locus_tag="C4R22_RS31295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025391.1"
                     /GO_process="GO:0006457 - protein folding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="J domain-containing protein"
                     /protein_id="WP_001025395.1"
                     /translation="MNIQEALNVFGLSGELTEKDIKAAYRKAALKYHPDRNPLGAELMK
                     AVNAAFDVLMANIDKINQFQSTDEHARYNYGDDLEKVLNVLSGLSGLVFEVIGNWVWIS
                     GETITHKETLKEIGCKWAAKKKQWFYRPDEHKSYWNREEHTIEEIRAKYGTTGQRRATG
                     WQRVETRA"
                     /name="J domain-containing protein"
     gene            30291..30833
                     /locus_tag="C4R22_RS31300"
     CDS             30291..30833
                     /locus_tag="C4R22_RS31300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001401654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001083906.1"
                     /translation="MNSFFEQYHPVFEVVCRILGNGWRVNKLDDCSSRIKLTSPQFKNY
                     SVHIRMEKDRFSVVGSVDSRSWRSPHHVCTLSRKRNPVDIAADIERKILVNASQEVLQA
                     IEYEKHQVEKKDEILILKGMLSQLVQLESWYGALTGFKAENGLNGKVTEQGDSYDLQIR
                     GLSIDQLVKITGYLKQL"
                     /name="hypothetical protein"
     gene            30830..31081
                     /locus_tag="C4R22_RS31305"
     CDS             30830..31081
                     /locus_tag="C4R22_RS31305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001565860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001230707.1"
                     /translation="MRKNKGDVTYFLEKEGDNYRLTKRIKARTNVKIGNKTTKITLYDA
                     VLNENELQHIDFTCAGLREDDETPVKNLIKEFMLNETR"
                     /name="hypothetical protein"
     gene            31068..31295
                     /locus_tag="C4R22_RS31310"
     CDS             31068..31295
                     /locus_tag="C4R22_RS31310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001541977.1"
                     /translation="MKPDNTPENVKKLRLKAGLTQKECSHIYGVGLRTWQKKEEVNTQN
                     SQSLSLVEFEFLLLLAGEHPEYVLCKRQSK"
                     /name="hypothetical protein"
     gene            31749..32048
                     /locus_tag="C4R22_RS31320"
     CDS             31749..32048
                     /locus_tag="C4R22_RS31320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001541978.1"
                     /translation="MKCSSVFTSTTNHVFTFERVTLCTIILMHKDTGQQYVVIFTDNNK
                     IRDYKIGIVPQFGELKQSDVDLVLFYRDEYEKYFDSLKDGDECLSFKDFIECLR"
                     /name="hypothetical protein"
     gene            32141..32491
                     /locus_tag="C4R22_RS31325"
     CDS             32141..32491
                     /locus_tag="C4R22_RS31325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000854261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001541979.1"
                     /translation="MKTLKQATMQFASDLRNNRCFKAAYNDALLELDREDLNAIVQCTF
                     LFEPKRTLAELDKLIKKIEVEEDYEFCVSLDKGKGWHEVRTFKSEREALDAYRILTLYG
                     YTVTIEKKEGND"
                     /name="hypothetical protein"
     gene            32765..32938
                     /locus_tag="C4R22_RS31330"
     CDS             32765..32938
                     /locus_tag="C4R22_RS31330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000882678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="WP_071821486.1"
                     /translation="MEDGKEPDTPFKGVFNVRLDPELHRRVAEMAMEEDLSLNAFVNKA
                     LEKEVSNHRAGA"
                     /name="type II toxin-antitoxin system HicB family
                     antitoxin"
     Typing          complement(25550..26556)
                     /name="IncX4"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.702"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          522..1747
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="99.022"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          7155..8221
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.719"
                     /coverage="100.0"
                     /evalue="2.69e-172"
     Typing          8764..9446
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.123"
                     /coverage="100.0"
                     /evalue="2.98e-137"
     Typing          9447..10351
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.338"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          12483..14341
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.032"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 gttggggtga gttatgaaga tgatagcgtt cagacttagt gatgatgagt taaaacttgc
       61 agagcataac gctatatcaa gtgggtttac cagcatcaat atatttgcca ggcataatgt
      121 gcttaatgtt gatgttcaac catcaaatat acctgtcagc aatgaatcat caaaggctgt
      181 taaaacctgt ttataccctc atgaaataga acttgttaaa cgtaatgctg cccttcacgg
      241 catgagcatg agcagagaaa ttgctattcg tgtgcgtcag tctttgttaa aaaatgaagt
      301 ctgtctttac cctgatgaag ttaaggaact taaaaaacta tcaactgctg tagatcgtgt
      361 tggtcgcaac attcatttta tcataaaagg tgaaagattc tgcacggtta acgatcctga
      421 tttcagaaaa gatgttattg aagtgattga actgtgtaag caaattgatt caaaacttga
      481 aacgttaacc aagagtgttg ttaaccgatt tgggtgattt atgggtgtgt atgtagaaca
      541 ggaataccgt attaaacgcg ctaaagggac agggcgtgat ccgaaatctc ctaagttatc
      601 gggaagacat atacatgcca gtaaatcggc ttttaatcat aaagtcagac atggcgcaga
      661 caagaaagca tatacctgga cgccaacaaa agaagtgact tttaaaatca ctggttcagg
      721 gaaaactgcc gcaggtatca aaaacggtat tgattacatt acccgtaatg gtgaacttga
      781 ggcttactgt tatgatggaa aaggttcaga gcaaacaggg aaaggagaag actttaacag
      841 ggagtttact tcaactttat ctaaaggaaa tgattactcc aggacatatc gtggagaaaa
      901 catcgatcat gtgaaaaaca tggtcttttc accaccacca gaagctggag taagcaggga
      961 agacgctctg aaagctacgg tagaatttct taaagagact tatccaaacc atgctttcgt
     1021 tgccgtatac catgatgata aagaagatca tcctcatgta catgttaata ttaaacttcg
     1081 tgatgaagaa acaggaagaa gattaagact tactaaatct gaaaccagga agttcagaaa
     1141 cggttttcat agaaaactga aaggtatggg atatgatgtt accgctacct ggaaaaaaga
     1201 tcccgaacgt aaacgggaga ttgagcgatt acaggctgaa aatccgaaaa gactccggaa
     1261 tgtttacaag gtggtggatt ttggtgagac ttcatatcag aataaggcag gggaaaaacg
     1321 aacacctttc ctcacttatg aaactttaaa aggtggaaaa caggttacga tttggggtaa
     1381 agacctgaaa aatcatttcg agtctgaaaa gcttcagcca ggaacgctaa tcaaagttag
     1441 aaaactggct cctacgcttg tacgtagccc gatgtttaat gatgatggaa ctgttgcagg
     1501 ctacagggaa acgcatcgca ataactggca gattgaaaat attgcccttg agcggaacag
     1561 agaacgtcag gttcatgagt gtgaaaccag gcaaccggaa gagagcgacg ttaaaaagca
     1621 gctatccaga aaacatgagc aaggtcacaa tatcgggttt gctcttgaac acgggtttac
     1681 aaaggattca gaagaacata aaaaactaag aatacagcag gagaggaact ggaaaggcct
     1741 ggggttttaa tttgatttcg gcgcaggtga acaaagcggc tactttgctc acctgctaat
     1801 cacaacaacc tacgagggag gttatcatga ctgagcatga tgctatctgc atttctgcac
     1861 ttcatcaaat ttttagtgat gaagaacatt tgagtgagca acaaaaagac attattctga
     1921 tgtacgctta tggctatacc ctgaatgaaa ttgctgattt caaaggacta aagccttcaa
     1981 ctgtcagaaa atatcttgat tctgtaagag ctgaactggg aggtgtctcg ttggcaggga
     2041 tcagaacact ggtactcatt cggactaatg cccttctcgt gtcaagtctt tccaggatca
     2101 gtgagagggg gaatttatga aaaaatatct gctttttgct ttgccgttct tcgttgttgg
     2161 ttgtagtgaa gaagtaaaaa gtgtggattg gtgggggcag catcttacgg aagctaaaca
     2221 aaagcaggca gagtgtgaga agtctggctc tgattctcag aactgtaaga atgttaaaca
     2281 agcattgttt attcagtctc agaaggatgc tccagtccct acattcgatt aactaatgtt
     2341 taaatcatac taaagcgccc atatgggcgc tttttttttc atgagcacac gaatcataat
     2401 atgaccatct tgtcaatggt atttgatcgt attgttgagc attgttattt tgcgaatcat
     2461 gttcgcatct aaaacaaatc caaaacacac ttatagtgga ttgattaaat gaaggagaaa
     2521 ccagataagt catcggaaaa aggggtttat gtcacaataa aactcgatcc aaggttgaat
     2581 gcatttattg aagagaaaac gaaaacatct ttgcttagta agaggaagca aattatttac
     2641 ttattaatgc agagtatgcg tattgatgga tatatggagc gttagctatg gcgtctttat
     2701 tcccagcctt gttgctgtgt gcggcgtcag ttcatccgga tacgataaat gatattgcac
     2761 gggtcgagag tggcttcaat ccttatgctg tggctgaaat tattcctgaa agggaacgcg
     2821 gtagctatgg caaaagtgtt atcagtcata tgcccaaaag taaggaggaa gctcttacag
     2881 ttatcagaga aattgaaaac agaaaaagac gttattctgt cggattgatg cagattacca
     2941 gcagtaattt ttctttttat tccacgtccg cagaaaaact ccttgatccg tgtgaaaact
     3001 tgtctgtttt cgaaaagatt atcgtggatt gttataaacg agggaggagc ctggagaatg
     3061 cgcttagttg ttactataca ggaaatttta gtaacggtaa gcgaaaagaa aaagaattta
     3121 ataatacaag ttatgttgag cgaattggtt atacagggaa cgaaaaaaaa tatgttgtac
     3181 caggtacaag aagcaacggg ggagaacagc gaaaaaatcg ttcacacaat gcgtcagtta
     3241 tctggcccga aaccattctg aaatctgctt ttgttgataa ctcacatcca acaaaagtta
     3301 ttaattaaca ggacttataa aatgtcattt aagaaatcag tatgtaatcg tatcagttca
     3361 tctgtcactg ctgtaatgca gcgtaaaaat aaggtagtta tggcagtcgc cggggcaaca
     3421 gtcgcatcac cggcctttgc ggatggattt tcaaaagcgg aaacactgct ggaaaaggtc
     3481 aaaacagggc ttagtggcct ttcactggta acggtgacta ttgcctgtct gtgggtcggc
     3541 tacaaggttc tgtttggtgg aagcacgatt cgtgaatgct cacctatcat catcggggca
     3601 attgttatcg ccagtgcggc tgaagttgca tcaatgatgg ttaactaata aagcggggac
     3661 gatagtatgt ctacacttta taaagcgatg acacgccctg ctatgtatgt gggtgttcct
     3721 gtcgtccctc ttactgtggt tgcaggggcg ttatttctgg cgggggttta tatcagcaag
     3781 ctgatctggc tggctattcc tgtcgcagtt tttattctca gaatgataac taagcaggac
     3841 gaccacattt ttaatcttta ctttcttaag ctgaaaatgc tcggaaactc agtgtgtaat
     3901 cgtttttttg gcgcacgagc gttcctctcc ggacaatatg aagctgttga aattgatgag
     3961 tttgttaatg ccatgaaact gaatgagcga atcactactg gtaaatatat accctattca
     4021 agccatgttg ataaaaatat tgtcaaaaca aagaacggtg attatgtagc gacatggcaa
     4081 ctgatgggga ttaactttga gtcaatctct gcggagatgt tagaaactat tgactcacag
     4141 gttgccactc ttgttcgttc attttccgga ctgcccgttt cattttataa tcattcatgc
     4201 agggcgagtt tttatgatgc ctttaccaca aaatcaggta ataaatatgc tgatataata
     4261 tcagattgtt attatggttc gatgaagaaa aataaattca aggggaacac tctttacttt
     4321 acgctgatct acagaccaga cgggcgtgta gaaaaactgg aaaaacgcaa aaaaagtatt
     4381 aaagaaaaga aagatgatat taacattcat gtgaagagaa tgaatgaaat gattaataca
     4441 ttctctggcg ctcttgataa atttacctgt aaacttcttg gtatgtatga ggagaacgga
     4501 aaggtatttt cttctcaact gtcattctat aattatcttc tgacagggaa gttgcaaaaa
     4561 atcagagtca ctgattctcc ggtgtataac gttcttggtg gagtggatgt gttttttaat
     4621 catgataccg gacagatatg ccgcattgat ggaaataaat tctttcgttc tattgaaatt
     4681 aaagatttct gtagtgagac tgcatccggt gtttttgatg tgctccagta ttctgatgct
     4741 gactatatta ttacgcattc atatacatcc atgagcaaat cagaagcatt gagtaccatt
     4801 aaacgtgcgg aaaaacagtt aaagagtaca gaagatgatg cggttactca attgcaggaa
     4861 ctggaaaagg caaaaaatga tattgtgtcc ggtgatatat cctttggtta ctaccatttc
     4921 acgctaatgg taatggcgga cagtatcagg gagcttgacg aatctgtaag taaaattacg
     4981 gcagacttta ctgacctggg cattattccg gcattgtcaa ccatgtcatt gccagcggca
     5041 tattttgctc agcttccggc ggtttttcat ttaaggccgc gtttatctcc ggtatcgaat
     5101 gtgaattttg tcgaactggc atcattccat aatttctacc aggggaaacg cgataaaaac
     5161 tgctggacag aagcggttgc tattctcaaa acaccaagca aacaggcgta ttatctgaat
     5221 ttacataact cagtactgtt taaagatgaa acaggtgaaa agaatcttgc taatactaaa
     5281 gttataggaa cggcgggttc aggtaagaca atgtttctgt catatcttgc ctgttcatta
     5341 cagaaataca ataaccccga aacttttgcc gattctgcaa aaaataagaa gttaacgtgt
     5401 gtctttcttg ataaggacag aggggctgaa ttatgtatcc gaatgcttgg tggggaatat
     5461 tacaccgtaa aaagcggtga gccgacagga tggaatcctt ttgctctgga ggcaacaaaa
     5521 cgtaaccgta tttttgtcaa gcaactgatg gagattctgt gtaccagaaa tggtgaaaga
     5581 ttatcgacaa gagaaagatt gcttattagc gaaagtgttg atgctgtgat ggatttccct
     5641 cctggcgaaa tgcgggaata tggtattacc cgaatgcttg agcatcttat gcagagagat
     5701 gatcgggatg agcaggagaa cgggattatc cttcgtttgt cccaatgggc taatggtcag
     5761 gctcatggct gggtttttga taatgctaaa gacacattca atattcagca tgtcaataat
     5821 tttggcattg atggcaccga gtttcttgat gatccgatgg tatgtgcacc aattacgttc
     5881 tatctgctgt atcgcattac gcagcttctt gacggtcggc gtcttgttat cttcctggat
     5941 gagttctgga aatggctaca ggatgaagca ttcagcgact ttgtctataa caagctgaaa
     6001 acaattcgta agctgaacgg gctggttatt ccggcaactc agtctccgga tgaaatactg
     6061 aagaataaga tttcacgggc tgtggttgaa gtatgcagca ccagtattta tctggctaac
     6121 cctgatgccg attacaatga ttatgtggaa gggcttaagc tgacaccaga agaatttaat
     6181 attgttaaaa atcttgatcc aatgtcgaga cagttcctga ttaaaaaaag cagtcttaaa
     6241 aagggggatg gtaaatcatt ttcagcactt gcaacactcg atttatcggg acttggtgga
     6301 tatctgaaaa tattgtctgc cagtgcagat aatctggaaa tttttgaaag tatttatcat
     6361 gaaggaatgg agcctgatga ctgggttcct gaatatctcg aacgggcaat ctgacaggtg
     6421 aatttatgaa acgtgtaaaa acatttatgc tgatatcatt attgacggct tcattttata
     6481 gcagcgcagg tattccggtt gctgtagatg ccagtccgga atgggctgtt gaagccgcaa
     6541 gatggacaga acgactcaaa caatggtctg aaactgcgca acattatcag agtcagattc
     6601 aggcatataa agaccagtta gccacagcaa caggtataag gaatattgcg gcattcacaa
     6661 atgaactaag taatctacaa tcagaactga caaatattta taagcagggg aacagttata
     6721 tttctgattt taccagtaat cccgaaggtg cattgagcag ccaggctaaa aatctgttca
     6781 gcaagtatgg agccttcgat atgtgtaata cgggctatga acgtaatgat aatctctgta
     6841 aagcacggat tgtgtcaacg gctgccagta ttgaacaggg aaatgagatc aataagcagt
     6901 tatcaagtgc aatgtctcag attcagagtt taagtagccg aattgaggct tcaaaggata
     6961 tcaaagaatc ccaggatttg gctaacgcat tacaggcgca gtcgttaaaa atgcaggcga
     7021 taaaaatgca gtatgatgtc tggaataata aaaataaagc agatcatgag atgttgatca
     7081 cgcaagaaca agaggccttt attaaacagc agaaagaagc tgaaccatta acttttgatt
     7141 aaaaggtgga tatatggctc aggggttttt cgttaaatat aattctactg ttatggattc
     7201 ggtagataaa atcagctcca gttatcaaac acaatttgct aatgatatta tgtcgttagc
     7261 gacggtatcg gttacgttat atgtactatg gaaaggatat caaatacttg ccagtaaaac
     7321 tcagacgccc ttgcaggatt tagtatggga tctatcaaaa tttgcaatca taatcatgtt
     7381 tataactaat gcggatgggt atttaactgc ggctactgat gcgttgcaag gcatgaaaga
     7441 tggtttttct ggaggggtga gtgtctggca aactttagat aacttatgga aaagtacgca
     7501 aaatcttggt gcggaaatat actctttaga taaatcaaca tatgttaaag atcaaggtgt
     7561 agttggacag tttttgatat ggactggctc gcttatttta atggctgtta gtgtggttgt
     7621 ttttttaaca gcagatgtaa cgatgaaact cctgattatt acagcaccga tatttatctt
     7681 ttgtctcatg tttggtttta ttcggagcat gtttaataat tggctacaat cgttattctc
     7741 cagtattctg acagttctat ttgccagttt agtgattcgg atagcaatgg attttcaagg
     7801 gatgatcctt tcccatgcta ttcgtgctgc acaaacaggg aatgtaaatc ttgtatctac
     7861 aggtgctatg ggctttatgg ctgggttttt gggggcttta ttggttctta tagctaaagg
     7921 ttttgctgtc cagttagcag gtgcaggtgt tgaaggtgct gttcagggtg cagccatgat
     7981 ggggctgggt gctgctggta tggctactgg taagtctctg atgcttggcg gtcgcgctgg
     8041 tttaggtttt ggcttaggga tggccggaag aacgggcatg aattctttat cagggaaagc
     8101 agggaatctg atggggcgtg gtgcgcgaac cgccgctgaa tgggcgggtg aaaagggata
     8161 tcaggcgctg gctccgacag gcgctttggg gatgaaggcg agaagacttg catccctgga
     8221 aaaagcgcga gcgaggaatg ccgcatgaaa ataatgaaac gtttttttta tgtgatgtcc
     8281 ctgaactgga tactgacgtt tgttgataaa catatcacct ccggatggag caggaagaga
     8341 aagctaataa cccagcttgt tattttaatc acgggaatta ccttatttaa ggtcttaggt
     8401 ggaatcagtc agagctggtt gtgacatgct tcattatttt gtcatgatac tttattttgt
     8461 cctaatcctt cttttaggag tgtttacctg cttcgcagga ataaggcttg gtttagggct
     8521 tgcgggaaaa tggagaaaga gtatggatct tcgcttttta attcttattg gtgggattct
     8581 ttttcttcat cttggccttt atctcttaaa ggtgttcgtg aacgcttaat aaggtgaatt
     8641 tatgcgatat gtgatttttt tgtttatcct gtttcagatt tccggatgta ccacaaggaa
     8701 tacccttcct tctgatgttt ccggcgaact ggaacccatt aatcacagcc aggtaatcag
     8761 ttatgagtga aaaaatcgaa aagaagattg agacagctaa atccttcgaa agacaactct
     8821 atgcagaaaa tgaacggtct aagaaaaatg catggcgtgt tgcagcggca gcatcattac
     8881 tgtccttatg tcttggggct gcaatttgtg ttcttgtgcc attaaaagaa aaagagcttg
     8941 ctattgtgtc tgttggcgaa aaaacaggtc gtacagaact gattactcag gttaaacagg
     9001 aaaagatcct gcaatctgaa gcgcttgggc ggtattttgt aaacacgtat attactttac
     9061 gtgaaggtta taattatccg tctcttcagt atgattatga gactgtacag ctatatagct
     9121 cgaatacagt aaaggacgat tatcttcgtc tgtataacag cgatatggct cctgataaaa
     9181 tttatcataa taacggttct tacgttgcgg ttgaggtcat ctccaatatt atttctgacg
     9241 caaccgcgcc agataaactg gcctctgtgc gctttaaaaa aacgacgaga aacttcacga
     9301 ccggacaggt ttcagtttca tactggacgg ctcgtgtgac atatcgtttt gaaccagaaa
     9361 agtcggttaa aagttccagt cgtgagctta atcctctcgg ttttactgtg accagttacc
     9421 agacagatcg ggaagtcagg ggggaatgat gaagaaatta tttattgcta catgtttatt
     9481 gcttcctggg cttgtgtatt cagcagcgac tccgttacct tctggatttg atgcaaggat
     9541 gcagactgtg agttataacg gtgcgaatac gaccgtaatc cggtcaaaga caggatttct
     9601 cacatcagtt gtttttgatg aaggtgaggc tgttatcagt gcaaaggctg gttttcctgc
     9661 cggatgggaa atcacaaccg atgataatgt tgtttacatc aatccgcgtc ccgttgttca
     9721 ggaacaggaa ggcgatgaag gcgaaaaact gaaaaaggtt ttccagccaa cagaaaagga
     9781 atgggatacg aatctttttg tcagaacaac aaagcggatt tacagtctgg atctaatcct
     9841 tctgtcagaa gaaaaacaag cgcaacctgc ttatgttgtt caattccgct atccatcaga
     9901 aatagcgaaa aagaatgcag aagaagtaag gctggcaaaa gaaaaacagg aaaaactcag
     9961 gcagaagaaa ctgatttctg aaagttttga aaaagccgat gcgcctaaaa actggaatta
    10021 tttcatgcga gtcaatgaaa aatatgacag tcgtcgtatc gcccctgatt ttgcttatga
    10081 taatggcata tttacctttt taggttttaa ctcagggaaa gcattcccag ctccatttgc
    10141 tgtaagagat ggtcaggaac agacacttgc ttttaatgtg gaaacaaaag gcaagtataa
    10201 aattatggtt atccacaacg ttaatgacaa atttgtttta cgctacggaa acagcgttgt
    10261 tggtgttgtg aataaatctt tcggaaaagt attaaccgac cagaggaata catcttctcc
    10321 tgcggtagaa cgtgttgagg tgaataatga ctgatatgaa aaaaacagat gatttagttg
    10381 atgatgctaa tcagtcaaag ctggaaagta aacccgttca tgatatcggt gatatcagga
    10441 acaaaaataa tcgtatgcgt tctggctttc tgtttggtct gatggctgta ttagttattg
    10501 gtatttttgc gctgaaaaca tataaaaatt attttgcaga tgaccagcag aaagcatcag
    10561 aatcaacagg cgataccagc atttctcagg taagtaaaat ccgtactggt cttggtcaga
    10621 attttgaccc tgttgagaat aaagcaatta tcaatccagg cgctactggt tctggtaata
    10681 ctgtttctga cggtcataaa gaagtgccac aggaggggtt caggaaatat ttgtcaatac
    10741 ctgttgctgg tcagggaggg agtcagactg gcgcgagtgg cagcagcagg acatcgcaga
    10801 catcagagcc acaagaagaa aggaaagaat caaaagaaaa tgtgcctggt aaatcaggaa
    10861 tgaaagtgac tgcgattaat ctcgaccctg atctctatat tgaggaaaac aggcttatac
    10921 cgtgtgcttt aaccacacgc tttgtttctg atgttgcagg tcgtatcagt tgtgttttta
    10981 cagaagatgt atggagtgct aatcaccaca caaaattact ggaacaggga actaaggctt
    11041 ttggtcgtta ccagaccgga acgctgaatc atggacaggg cagaatgttc gttatgtggg
    11101 agcagttgcg gacgcctgat aataaacgaa tcgatatggt aaatacagca gcggctggtc
    11161 ccctgggaga agcgggcatt gatggatgga tcgattctca cttctgggag cgttttggtg
    11221 gttctcttat gctcagtatg gttcaggatg tagcggctgc ggcggcggat aatgcacctg
    11281 gtaaagatcg taatgtggat tataccgaaa actcacgaca ggcaatggct gaaatggcta
    11341 aagtcgcact tgagaattcg ataaatattc ctccaacaat gtataaaaac cagggtgaca
    11401 taatcactat tatggtcggg gaagacattg atttttctga tatctatgag ttaaaggtaa
    11461 aatagtatga atggcgttat tcctgtcagc attagcaata aatcgctcga tttttataaa
    11521 aatcaagtat tccagtcttt tcttgatatt gaagggctaa cagaaattgc tgtcaaccgt
    11581 cctggtgaaa tctggacgga aattaatggt gactggacat tccataataa tgacagtgtg
    11641 acctttgatt tttgtaaacg tttttctcag acgctggcat catttcgggg agatgaaatc
    11701 ggcgatacca agccattact ttcagcaaca ctggaatcag gagaacgtgt acaggtcgtt
    11761 tttcctcctg catgtgagag aaatactatt tcaatcacta tacgtaaacc atcgacacgg
    11821 cagataacgc ataaagaata tgtggcgaac ggtttttatg attatgtcca gtcaggaaaa
    11881 aaacacagga catacgatga tgagcttctt gatttattca gagcgagaaa tatcgctgct
    11941 tttatggagc ttgccgtagc agcagggaaa accattgtat ttgccggagc aacgggttcc
    12001 ggtaaaacaa cttatatgaa gagtcttatc gatttcatac cattgaatac acggctgatt
    12061 acgattgaag atgcagagga aatcaaattt tttatccata aaaattatgt gcatcttttt
    12121 tacccttcgg aatccggcag tgattccggc tctatcataa cagcagcgaa attaatcaaa
    12181 tcctgtttga ggatgaaacc tgacagaatt ttactggcgg aaattaaagg tggcgatgcc
    12241 tgggattttg tgaaagttgc tggttctggt cacagtggaa gcatgacgtc cattcacgcg
    12301 gcctcggcaa aagatgccat cattcagatg gtgacaaaat gttatcagaa cagagaatgt
    12361 cagaatcttc cttttgatgt tcttcgtaaa atcattatgg acagtattga tattgttgtt
    12421 catgtaggca gggatggtgt tgttaggcat atgagcgaca tctattacaa aggggctgaa
    12481 tgtgaaaact tttaataagt cgcaatctgt ttttatattc gctgttatgc ttgttgcggc
    12541 atggttcgca ggttcattta ttttctttgt gctttacttc agccagataa agaatctgaa
    12601 accattgaag gctgtgttca gatccattga tgcgtacagg atggatattt ttacagacag
    12661 ccttacttta tctgttgtga ctacggatat cagagtttta gcctttgttg cacttggagc
    12721 aggatttgtc gtgtctctta tcatccctgt agcggcgttg ataaaactga acgagaagaa
    12781 agaaaatatt ttcggtgatg cgcgatttgc gacaattaat gatattcgtg agtctaacag
    12841 tttcacgctt gacggtgacg aaaaagacgg gattatcgtt ggtataaaag acaagaaaat
    12901 catacgctat gtgggagcag cattcagtgc tatgggagcc ggaacaaggg ctggtaaagg
    12961 tgctggtata gtcatcacta atcttatgaa gtattggtgg agtgttatta ttctcgatcc
    13021 caaaagggag tgttttaata tcaccagtct tatcaggaag gtgattttag gtcatgaggt
    13081 ttataaattt gatcccttta gtccggtaac gcaccgcttt aaccctttgt attatgtcag
    13141 catggggacg agtgaaggtt ttaatcagct tgaaaatctt gcgttgatta tttaccccta
    13201 taagacagat ggtgcggatg ctggtagcta tcttaataag acagcgggag gtgtttttaa
    13261 atcttatgct gtcgctttat ggtttatgat taagaatgat aaggctggac taaaaacgct
    13321 tgatattgat cctgtcttct caatgtctaa aattaatcag ctttttgagc gtgcagaacc
    13381 cgaacatctt ctttcattca tgaatgatat tcgttcagaa ttaaggggga aagacaaaac
    13441 gcttgctgat attggtgtag ctggcctcaa ggcgttcatt gagatggagg ataaaacaaa
    13501 agcacaactc aaaagcaact ttcttaatgg attatcaccg tttgctaacc ccaatgtagc
    13561 aaatgctact gatggaaatg attttgattt gcggcaggtg cgaaaaaagc ggatgacaat
    13621 ctatttctgt atttctggtg ataacgccag gttagctgaa aaaataacaa atattttctt
    13681 tcagcttgct atacaggtga atcttgaaaa gatgccaaca gatgatccgg aaataaagca
    13741 tgactgcctt tttcttctgg atgaattccc gtcaattggt gctgtagatt acatcaagag
    13801 caaatctggt ctcattgctg gttacaagct gaaattattg attgtttacc aggtcggctc
    13861 tcagcttgaa gaaatctaca gttatgcagg cagtaaaaca ttactggcaa gtgcaccctg
    13921 caaaattgtt tattccgctt ctgatgttaa agatgcgagg gagttatcag aagcgatggg
    13981 aacacgaaca gtaactatcg gttcgaaaag caaaagtcgt agtcgtggag gaacatcgag
    14041 atctgaatca gaaagtctta ttgagcgtcc actggtaaca acaaatgaac tacttacact
    14101 gaaatttagt gaagaaatcc tggcaatgaa gggagaaaac ccgattcgtt gtgaaaaggc
    14161 attctactat ctcaatgagt atttctttgg tgactttgtg aaggttgctc cggaacttgc
    14221 aaacattttc cccaggaaaa aaggaaagct ggttatgcct ccacagaaag tatttgaaaa
    14281 tgaaatcgtc gcaaaagggt atctggcagt aaaagatgtt cctgatctcg ataaagcggc
    14341 gtaaaggaga acatgatgaa gaaattagtg gttttattga tttccattct tgctggttgt
    14401 tcatcaccgc cagagccaac acccgtgcag tttgaaaagg caaatgaagt gatcaatccc
    14461 tcattgccat atgtccccga ttttcatggt gtcataaagt cagacgttag cggtaaagga
    14521 tgggtttatg agatcacttc cttatccgga gtaaaggcca gaacgccgac gttttattac
    14581 gctctggctc atgcggacag gattgtagtg acaacacatg atgctgggct gtggtttcga
    14641 atcagagatc tgttgaagat ggaaggggca acagcagtcg tggaatggcg aaacgagaaa
    14701 agttttttac ctgaacaggg aaaaatagtt ttcattaaag cacaaaacga ggtgaaaaat
    14761 gactggaaaa aatagagtgg ttttacctgc cttgctggcg ttaggattaa tatcaacaaa
    14821 tgctaatgca tctgaccctt gcgcttcggt actttgctta tatggaaaag cagtcgggca
    14881 aggtggaggg agtgagtgca gaagtgctga aaaggatttt tttaatattc tgaaaaagaa
    14941 aaaaggaagc attcgctgga gtaaaacttt tgatgcccgt aaagcatttc tgaatcagtg
    15001 ttcaacggct gatcctgctg ctatatcaaa aatcatgagt aagttcggca aggttaaagg
    15061 gtagatgata tggaaaagca aactactgat ttactgaatg taatcaagac aggacactct
    15121 ggctcaatag ctggtaatcc tgctcatgca ctggatgata agactatgaa cgccatcatt
    15181 cataactacg tggcaacgat tgtgctcggt aaagcaggta actgcaaaga aactcctctc
    15241 acaaagtatt gttcgaggac tatgccagag cgtatttcag ttgaagaaat taatgagttt
    15301 aaaatttatc cagagttatt ctgaacggag ataacggcaa acgccgcaga ttccggattt
    15361 taatccggga tttgcggggt tgaacaaccg aagggcgtta gtttcctcgt aatccatgag
    15421 gtgtatatga aagcaagaag tgtgagagtt gccggaattg aaattatcga tagtgttaaa
    15481 acggtcgctt ttgtttttac tgaaacctta ctgtttatgg tctggttttc ggcaattgtc
    15541 tatgggcttt atcgtgttgt tatcgtttta tgggatgatc ctttaaagcc gcaatcgctc
    15601 atggaatttc ttaatttcat agttgagttg tatagctatg tacttccttc gttggctgtt
    15661 atcgcagtgg ctttaatcgc cgttttatcc atttgtaaaa tactctcagc aatatgggag
    15721 ggaagaaagc aatgagacat tttcttaagg ctctttcctt tgttgtttcc ctgttaccag
    15781 ctacattgtg tgcggctgaa atccagggga aagttattcg cgttctcgat ggcgacacca
    15841 tagaaattaa aacactaccc gcaaaaattg ttgtgtatga agttccgatc cgagtccgat
    15901 tgataaacat cgatgcccct gaaaagaaac aaccttttgg acgctggtca actagtcagc
    15961 ttaaaactct ggttgcaggt aaacaggtga cagtctctta ttcacataaa gaccgctacg
    16021 gacgcattat cggtcatgtg ttcacgacga acggcacgga tgccagccgc tttatggttc
    16081 agtctggcgc tgcatgggta tatgaacgtt acaacgtgga tgagtcatta ccggctctgc
    16141 aacgggaagc gcaggaacaa aaacgcggtt tgtgggccga tgcaaatccg gttccaccgt
    16201 gggaatggcg atacaaacat aactaactga tagaggtttt tatggcttta tcacccaaag
    16261 aaaagaaaga gttacaacaa cgcttcgaaa agcaattact acctgacctt gatatgtcat
    16321 ttgaactaaa tggcgaagta tataaattta attttgataa aaatgagtca ggtgactata
    16381 tcgatagttt tacacaagca gtatggggag gttatcagga tgccgaggaa tgggaaaaat
    16441 atggtaaaca tcaggagaca gaattacctg aatgccctga accagtcgag ggttggtgcg
    16501 actgtgataa atgtaagtcg atgatttttc ataaagagaa aaatatttat gtttgcctct
    16561 cctgccataa acaaacagag ccatttcttc caattgactg gaactcaaac gattacgatt
    16621 ggctacctta tgaagatgaa tactaatgct gaatacttca cagtcataat acagattgtt
    16681 ctttattcaa aagacaacca tctattgaaa gtgcattagt tatataaatc agatactctt
    16741 tggtggttat tatgcaatat gcattagttg atgcgctgga acgaaaattt ttgctggatg
    16801 ctcttgaatt tggtgttctg aaggactgga aagaaaatcc ggtaaaagaa cttcctgata
    16861 ttgatgaatc tgttcacccc ttccatgtct gctatggtgg atatttatta aatcctggtg
    16921 tttcagattc agatattagc agaaaaataa aagaccagac aggattctgg ctggcagcta
    16981 ttgatgatac ccgcatggat tgtcattcaa tagcttatta tgatattcac accctccctt
    17041 tgattttgtg tggacatcaa aagatagttc cttttgccgc attaataaaa gctgatgaat
    17101 gcatcatttc aaaaattgct tcatattctg gttttgctgt aacagctttt ttgagaatta
    17161 aagaccagga tatcgcaacg aatatactta accgtgaggg aatttttgcc tttaatggct
    17221 gtgagcgcag attcagacaa cctgtaagtg aagataactg gcaacaggca gtatcagaag
    17281 aacgcgctat tcgttgtgca aacagattaa ttcaatgtaa aggataacaa aatgagactt
    17341 tttatcgcag aaaaacccgc agtagcaaat gatattgtta aggcacttgg tggcaatttt
    17401 acccgccatg atggctggtt tgaaagtgat aacgccattg tgactaactg ttttggtcat
    17461 attatcgaat cacaaccgcc ggaaaactat aatcctgaat acaaagcctg gaaggttgaa
    17521 acgcttcctt tacgtcttta tcccgtgaag tatcagcctg ttgaaagtgc agcaaaacag
    17581 gttaaaacga ttctcgaact tatcagacgt ggagacgtga ctgaaattgt tcacgctggc
    17641 gatcctgatg atgagggaca gctacttgtt gatgaagtcc tggaatatgc aggaaacaca
    17701 aaacccgtaa agcgcgttct gattaacgac aacacgcttc cggcagtgaa aaaggcactg
    17761 gcaaatctta aagataatcg tgatttcaaa gggctttacc ttaaggcgct ggcgcgttca
    17821 gttgctgatg ccgtctatgg cttctccatg acgcgtgctt acaccattcc tgcaaaagcc
    17881 agaggatatc agggcgttct gtctgtcggg cgcgtccaga ctcccgttct tggcctgatt
    17941 gtgaatcgta cccgtgctaa ccagaaccat aaatccagtt tttactacac catgaccgga
    18001 gtctttcagc gtggtgctga tgttataagg gcgaactgga agccagggga atttgctccg
    18061 ctgacagacc gtaaattact tgataaagcg tgggcagacg gaacggctgc atcccttgca
    18121 ggaaaaccgg ctacagttga agcagcagca actgatgata aaaaaacggc tgcaccgttg
    18181 ccctttaacc tggtacgact ccagcaatac atgaacaaaa agttcaaaat gacggcacaa
    18241 aaaacgctgg atattacgca acaattacgt gaaaaatata aagcgattac ttataaccgc
    18301 tctgattgct catatttatc tgatgaacaa ttcagcgaag cgccgcaggt tatcgatgcc
    18361 ctgaaatcag tctttcctca gtcgctggat attgattctt cacgtaaaag caaagcgttt
    18421 aacagtgcaa aggtgactgc gcatactgct ataatcccga ccgccagtgt gcctgatgtt
    18481 aacgcactca gcaccgacga gcgcaatgtt tacctggcga tcgcacaaca ctatcttgtt
    18541 cagttcatgc ctgaaaaagc ataccaggaa gtatcggttg ccattcagtg tggtgatgag
    18601 tcgttctatg cccgtgccag aaaaacaact gacagcggat ttgaggcgtt tcttggcgcg
    18661 gaaaccacag acgaaggtga atcagaagat aatgatgatt ccgcttttga actgctctgt
    18721 aaaattcgca caggagaaac actgacgaca aaagaagtta ttgttaatga gaagaaaaca
    18781 acaccgccgc cgttattcac cgaagcctcc ttgcttgctg cgcttgttcg tgtcgcggat
    18841 tttgtcactg acccaacgat taaaaaattg ttgaaggata aggataaaga caaaaaagat
    18901 gaacatggtg gcattggtac gccagctacc cgcgcagcca ttctggaaac gctgaagaaa
    18961 agaaactata tcacgctgga aaaagggaaa cttattccta ctgataccgg atatgcgctt
    19021 attgatgccc tgcctggtat agcggttaat cctgatatga cagcattatg gtctgaaaag
    19081 caggctgcca tagaaaatgg cgatctgacg gttgaacagt ttattaatga tctgtacggt
    19141 gaactgacag gcatgatttc tgatgttgac ttgggcgaga tgaagattga acccgctgcg
    19201 ccagcagggc agtttcaacg cctggactct ccctgccctt cctgtggtaa acatattgtt
    19261 atcaggccga aaggttattt ctgtaccgga tgtgaattta aaatctggag tgagttttat
    19321 ggtaagaaaa tcacccaggc acaggccgaa aaactggtta aatcagggaa aaccgatttg
    19381 attaagggat ttaaaaagaa aagtggtgga acgtatgata cagttcttgt ccttgaggat
    19441 aagaaaacag ggaaactggg ttttccggca agggctaaga agtgaaaaca aagcaggaat
    19501 ggctttttca gttaagaaaa tgtacatcaa gagatactct tgaaaaagtt attgagatta
    19561 accgttacaa actgccttta tcagaatcag aggcatttta ttctgccgca gatcatcgcc
    19621 gagcagaact ggtgatgaat aaactttatg ataaggtgcc ttccggcgtc tggaagtacg
    19681 tacactaaat aagaggatta attatgagcg aactgactaa agaagatgaa tacggcatta
    19741 tcagccgtac tatgatgaat attcgttcat tgcgtgtttt tgcccgtgaa gttgattttg
    19801 agcaattgct cgaaatgcag gaaaaactga acgttgttgt tgaagaacgt cgtgaagagg
    19861 ctgaacgtga agcggctgaa cgcctggaac ttgaagccaa acgtcagcag gccattgaat
    19921 acatcatatc tttaggtctt gatcccgaat cactccttgc tcctgtaaca gcagatacag
    19981 taaaaaccag gcggaaagcc aaaggcggag taagaaaggc taaataccgc tttaaggatg
    20041 aaaatggcga gatcagagaa tggtctggta atggcaagcg tccgcttgct ttacagaagc
    20101 tgcttgatga gggccatttc atggaagatt tcctcattga caaactgcaa cctgggcagg
    20161 ttgaataaaa taatcgtgat gccgtcgcaa acaagtttgc gacggcaaat ggaggggaca
    20221 gaacagccag cggtgctggc aagaaatttt atcgtttgat aaagagggaa aatgatgatc
    20281 aaatcaaaaa aagtagtggt tatttttgtt gctttgagtt cattcttgct ggcagggtgt
    20341 gattcaccaa aagatgctaa taagcaaaac tttgaaaaag ctattaatac tcgactagag
    20401 aaggaatgca ttactattag tccgctggga atgtttgata gtaagcctta tccggttcag
    20461 gtagctgtgg ctcaggctaa tcgatataca tctcaggaac gggcagatga aataaattct
    20521 cgacagtttt ctgcgctgga tgtactggtc aaagccgatt tattaacagt aaaagatacc
    20581 ctggttgatg acgttattgg ttttactaag acgggtaaga aagtgccagg ccgtgaatat
    20641 gctctgacag atgaggggaa aaaatatctg aagtctccgg aacggcctga tttttgcgtt
    20701 ggtcattata aggtggatga gatagttgat tttaccgaac ctggtgatgc tatgggaatg
    20761 aagatcacgc aggtgaatta cacattcagt cccaccagta tcgctgaatg ggcgaaacgc
    20821 gatgatgttc ggacagcatt tttaggactt gagtctgatt tgaaagagaa acaaacaaaa
    20881 cgtattacac tggttttgaa aaatgatgga tggtctgctg aacggtaggc tgtaatggtg
    20941 ttgctacgtg aaaaatcccc cacgtatatc ccctactttt tcacggattt cacgtagcgc
    21001 accgccgtta atgactctat caaaaatact caccgatatt ttccgcaccg caaacaacct
    21061 aactcactgt aaaacaacaa atcagcttcg cgccggtgac gcatcgatcg cgctggcctg
    21121 cgcgatcctc agctgcgacc gctacagtat ttttgaacaa gatttccctc gctccgggca
    21181 gaccatgcct tactgacagc cttcgccagc gtgacaatcc cggctccggt ttaattcgcc
    21241 aggcagttag acattcaggt cattctgtcc atacctcatt agttacaaca ttcacatgct
    21301 ctgttccttt atccggtgcc ctgttccggt atatgtgccc atatcctggg ttattcagga
    21361 taaccgcttc cttttcgccc tgccctgtcg ttcatatccc tctggacaaa aatgcattat
    21421 cggaaaaaat gtccaaaatt ttttttggtg atcggaattt ttgttgtcgg acgcacccct
    21481 gcttcaggtc ataattgctg gcacgtccaa aaaaacaggt gcggagatta aaaaattgag
    21541 tcacttaccc gccagcattt tccagatttc acgtagcgac gcctggaatt taaccatctc
    21601 tcccgatgca gcccgtaata tgcgggatct tgcagcacag attggcgcag gaatgccgaa
    21661 atatctgata gcaccggaag tctcactgct tctctcctac atcgatgatc tgaacatccg
    21721 tatgtacttt gagacgctct ggaataccgg agcacgactg aacgaagctc tggcgctgaa
    21781 acctgccgat tttatgctga ctccgacgcg gcagtacccg caacccgtgg tgatcctgaa
    21841 aacactcaag caacgtctaa aagaagcaga aagaagacca ggacgcccga ccaccaggca
    21901 tccaccatta catcctgatc cgcgatacag aaaaccaccg gagcctgctg taaggctggt
    21961 tcctgttctg gatgccggat acgcattgcg tatgcgggaa tacctggcga cctggaaaaa
    22021 gcggatcaaa catcagcctg tgtgggacat aacatcgaga cagacaccgc tgaactggat
    22081 caacaccgca gtggcacggg cagagcgtga cggcgtaaca ttttcggttc cggtcacgcc
    22141 tcacacgttc cgccacagtt acgccatgca cctgacaatg agtggcgttc ctccgcgcgt
    22201 cctgcaatcc ctgctgggac accgttatgc aagaagcacc gagatttaca cccgcgtttt
    22261 ttcgctggac gtccttacag gaagtggcct gtcctttacc tgcgatccac agcttgcaaa
    22321 acagcttctt ggataccctg atgcgcctta ataatgaata ataatacaca ccattaaact
    22381 gttgccagca cgcaattgta cggttatact ttcatcacat aaaattgtgt attaatacac
    22441 actatttaac caagaggatt ttgtgatggg aaaaatcatt acagttgcag ggcataaagg
    22501 cggcataggc aaaagcaccg tgctttgttc cttatgtgtc tgtgccatca ggaaagggaa
    22561 aacagcctgt ttcctggaaa cagactcgca gggaagcatc aaggacttca tcgaggaacg
    22621 taaaaccaac gagcggctgt ctgaaatacc gtatttcgag tgctacacag atattccggc
    22681 gatggcacga aaactggctg cccgctttga ttatgtgttt gttgatacgc caggaatgaa
    22741 atctccggcc ttcgttaagg cactgagttg tgctgacatt ctgttcacat tcattgagcc
    22801 aggagcaggc atcgagatca acacgctggg acggctggtt ttcgacatta aaacagcaca
    22861 ggccggagtc aatccgtcaa tgaaagcatg gattgtcctg aataagtgtt caactaatcc
    22921 gtcagacagt gaagcgtcag aactgcgccg acaactcaat gatgatcctg actggcttcc
    22981 ggttccccgt cagcgtatct atatgcgtac tgcgcataaa aaagcctata acagtggtat
    23041 gggcgtacac gaatacgatg ataaacgggg aaacaaagcc cgtggagaga ttgaattact
    23101 gttaaaagaa acgggggttc tttgatgtgt attattacac accataaaag atgatatgat
    23161 tacatcataa atagtgtgta taattacaca ctttacaaga acaggatacc taatctaatg
    23221 gcaaagctcc caaagaaaat tgatcaggaa attaaaccgc tggatttacg ccagtttgta
    23281 agttctgctg cacaaaaacc agcatcggca tccgcagtaa cgcgtataaa tctgaccatg
    23341 acagatgatg atctggatac agcgcaggtg ttccagaaca agtacggcgc aagccgtgct
    23401 gaagttatca gagcagcact ggcagcgtta cgtctggtat cagcagaaga acgccggagg
    23461 ctgttcgatg atataaggaa aaacagcccg aaagccggaa gaccaaccgt aaataaatag
    23521 cgtattttat tacacactat taaatgaggt aaaaatatgc tcataaaaat cattaaatct
    23581 gtgttcaatt tttacatgct ctgtgtgcag cctttacttg gattatttct cgtgggttac
    23641 agtatatgga gcttttcagg tgacggtatc tgtacagcag acaaagttat agcctgtgat
    23701 atatcaatat atctgaaacc agcattttac cttctcatta gcactattgt tttgtttgta
    23761 gggtatatag catggcagaa ataacgctat aaagaagaag actttaaatc aagcattaag
    23821 ccggaagatt ttgtgaagtg agtaatgcca gtttgtagcc agacattagg gcactttagg
    23881 agattttcaa tctatggaac actgcatctt tgatttaggc attatagact ataatcctgt
    23941 cattacatgg acagtacctg ttgcattttt ctttttagta gtgctggctg gtatagtatt
    24001 caatattggc aggaaaagta atctaatcgt tttcatcctg gcaatgttgc tcccagtaac
    24061 aacggttttc atttttatgt tactgggcgg taagatcgat atgtgctgat caattaaaag
    24121 aggattaaac aatgataaat tcaatcgcgt ttagtcttat agcgttatgt ataacatata
    24181 tatcatcact acttaaaaaa agtaacttca gaatatttta tattactgta tctacgtgct
    24241 ctttattatt atcatgagta ccaaacaagt acggtatgat tggtatagca gcattggtat
    24301 ttacaactat gttaggacca ttattaatta ttttagagga taacagataa taaattatga
    24361 caatgcgttt gttaagcccg caaatatgtg ggcttatttt taatttctaa tatttttact
    24421 cttcatcatc ccgcaggaac tgacaaaaat cttcgctccc catcatatcg acagtgtttt
    24481 taaattcgaa aaaagaaatt cctgtcatag cacacacgcg ctggataatc agttttttct
    24541 tttgctgtct gacggttgcg gtttcaccaa actggataac agccaggact gtttcatcat
    24601 atgatttcag gacaaaatca caggttatat tctgcacttc acggattaaa tcttttacag
    24661 cttcctcgct accatgagga cgaacaaatt caatgagccg tattttggga aaaacggaat
    24721 aatcaggtat aatattacgt gaaagaatgc ctaaaaactc tgattcctta tttgagagta
    24781 atggtacttt agtaaaacaa tcaacctccc caatggctgt aaaagcattg gttgtcaaag
    24841 ctggattgtt cttaataaaa tcagagaata cattttcagc tgatggcaaa acaacagaaa
    24901 aattctgttg ttcatctcgt tttttattac ggttaaatat catttcatat tccttttaaa
    24961 agagcctgcg gcaggcacag gcaaaaacat cgtttttgga caatcatgga taaaatgtta
    25021 acattttgac catgattgtc tatcctgcat tgtcttttac agtctgtaag atcggcactc
    25081 attcttccgg cgttctcccg ataccaaaaa gacggaacgc aaaacgactt tcgatccacc
    25141 attcaaaaat ctgctctgcg caaccacaaa cagttaaggc gatccatgca gcaagaacaa
    25201 cgtaaccact gacatctgcg cccatatacc aggcgatagt taaacccatc actgcgatac
    25261 cgcctaaaaa ctgcaacaag aaacgaaatc ccgcaagaat ccccaatgga ataacaacaa
    25321 ccagataaag ggaagcagcc agaaggtatc tgacaggtgt cagcagataa aagaacctag
    25381 atgttttctt tttgtcagaa taaacggcat catttgcaac atctgttgaa tgagcgccca
    25441 ggtctctcct gatacgttga aaatccacga tgttatcttt catatcatcc tctcttttaa
    25501 gtgagttata aaaagagaaa aaacgggtaa cgtaaacagc agcattcttt aatcactaaa
    25561 ccagaacgac tcttcgaaat cccatccggt tatttcatgc cataacttaa ccttctgaag
    25621 atctggcctt gataatttta acttatcatc atattccctt aaagagataa gataattttt
    25681 cataacatcg atacattttt ttgcccaggc tacctccgca gagcttcctt taataactct
    25741 tggtcttgat ggcaatcgag ggcgtaacgg tttagttgct attttttttc catcatgtgt
    25801 ttcattctct acaagatatg tgaacacaac agactcgatc tttctgccgg acttgatacc
    25861 ttcataggta acactcagat tcgtatttgc attgataata tcaacagcag gatcaagcac
    25921 ccgtttctta aaatccttat atactggata tttccctgta agcccggttc gctccttcat
    25981 ccattcaatg gttataggat ctgtcgagat cactccacta tgtttcttat ttctgttcag
    26041 attcttatat ttatacaacc atgaataaag tcgaaatgaa aatggcgtat ccagtttcac
    26101 catatgttca agattcattt gtgtaaattc gcttttcagt tcataaagat attgactaac
    26161 cgaatctgaa aaacgcaaag ttatgtcact ttcactattc ccaacaccat atcttattga
    26221 agaaaaccag aatcgtttga ctgcatcgat cctttttttt gcctcgttcc attcatacgt
    26281 aacaattggc tttgagccta aagaactcgc agcagatttt aactgttcat aacaattttt
    26341 cgaatctaaa gaaaaagtgt ccctgtattc cttcgcaaac aatgtatatt catttgcagg
    26401 ctgtggttta cggctatcaa tcttagtcaa tgccagatac agaagacgca tttcaattag
    26461 cgttatatcg tatgcacctt ccagcaattg atttccctgt gccaacaaac tttgaacatc
    26521 attacagtcg ctatttttat tattctttaa gaccatacag ctccccttcc cgtgagttaa
    26581 aaatcaaaag aagtttctca cacccaaact agggacgcaa tttttttttg tccctatata
    26641 actaataaac cataaatctg tcccccgttt gaagggtcaa acctggctga acggcgcatt
    26701 ttcaccctca gtcagaggca gtcaatacag caaaccagga gggaatgcat catcaaaaac
    26761 ccatagagcc aaacatctta aatgtgatct aagtcactaa ttaaattcag attcatagag
    26821 aatccataac gaatccgagt tgaatctaaa aaaagttatc cacaacctgt ggataaaaaa
    26881 gttatccaca ctaaatctgt ccctagttga ccataaatct gtcccctttt aaccataaat
    26941 ctgtcccctg ataaaaacgc aaataaccat aaatctgtcc ccttttaacc ataaatctgt
    27001 ccctagctag cattgcaatc aattgaaaaa caaaagaaaa aacacccctg aaaaaggaaa
    27061 tattatatgt aacataggag tgatctatct tttagaaaaa agaaattaga aaaaaagaat
    27121 agagcgcatt gtgaattttt tgagttggaa tcagcaaaat cacaagatga ggtcagacca
    27181 gagcgtacgg attcatatgc tgcatcgaag acattccgct tcctcgctca ctaactcgct
    27241 ccgctcggtc gttcgactgc ggcgagcgga gtcatttctc acatatcgct ggtaattctg
    27301 ttgttgttcc ttcggtgatg agtcgcttga tagcctataa aacacgctca gaagctctca
    27361 gacgcacgaa acgggtttaa atacccctta gggcatggga ggcgcgaaaa acgcttacag
    27421 aggctttcta ttcatcagaa tctgatcctg tgaagaccga gaaagttctc atgtttagtc
    27481 acaacctaaa tatttcattc cgagggcggt ttaatataac taactgattt tattggaata
    27541 gttcgtttaa ttatgatcct cattttgcta accgaggatc ttctcatgtt tcaattaaat
    27601 acctttaata tcaacatgat atgttctttt gccaattgat ttatgtgacc acatcatttc
    27661 aacgatacat aaatcaacag attcagcaat gccccctccc caaagtgtca cagagaagcc
    27721 ctgaatcgct ctctgccgct tcgttcgata caaccatgag gaaaaccatg cgaaatgaaa
    27781 aaaatcgctc agaatgcgat acagcgcgtt ttagagggta tttacaaaac agtcgttgcc
    27841 ttgaggaaat tttgatcaag attgaactcc tgtccggatc atgccgacag atcacagcaa
    27901 caaggccact aaaaatcgtt gagctgcgtt aaaagctgtt aaaccgtggc tgactacaac
    27961 gaaacgggaa aaaccgctca gaatgcgtta cagagcgttg catatctcat tgtggcgcaa
    28021 ccctatatta gcctacaagt taattcaatc ttgcagaaaa ttagcctgta ggttaatata
    28081 agcgaaaatg gaggtcacat gtttagcgtt gtttatcacc cggaagccag ggaagaagcc
    28141 acagcattac ccttaaaaat cagggtgaag tttgaccgtc tcattggcaa actggagtat
    28201 gatgctcgat tactgcggga gccggacaca aagcctctcg gcgatggact ttttgagatc
    28261 cgcacaatgg ggacagacat tgccaggggc atctgggtat accacaaagg caacactatc
    28321 atcatgctcc gggttttcat caaaaagtca cagaaaacgc cagtgaaaga aatcgatctc
    28381 gccagaaagc ggttagcgga ggtacttaat gaaactggta agccataaag aactgcataa
    28441 cgagtggatg caggacgatg aatatcgtgc tgcgtggcag gaggaagaac gcaaagagaa
    28501 actcagggag cttctcgcgg aatggcgtaa gcatgacaac ctgacaaaag cacaggttgc
    28561 tgaacgcatg ggggttacac ctccggtcat ttcccgtctg gaaaataaca tcactaaagc
    28621 cagcatcgac acactgacgc gctacgctca cgcctgcggt attaaaaaac cagtcattgc
    28681 cctgtactga ggaatcagcc gcagatgagt aaaactgatt atccggcatc cgttgatcac
    28741 aatgccgcca tgattgaaga attgcgcgca gatcctgatt atgcaaacgc ttatcttgct
    28801 aatgccctgg aagaaataaa cgagcctggt ggtttaggtg gttttcttgt tgcgctacgt
    28861 caggtaatcg aggcgcgagg ggggatttcc gaagctgcca ggaaatctgg ccttgcccgt
    28921 cagagtattt accgcgcatt atcccccaac ggtaacccga ccatcacaac gcttgcacaa
    28981 cttacatcgg tagccggatt acagttcact ctcagtaaat ccagccacta atctctccag
    29041 ttccccctaa gcgggggaat ttccatgcca tcaaaaccgc agttatcccg cccgacgttc
    29101 accggtattt aatcggcaaa tcgtacaatt gcgtactggc aatagtttaa cggtgtgtat
    29161 taatacacat ttaaagacga tgtgatagat gcgtgtgtta atgctaatgt atgcatacat
    29221 tagcattaac atagagcaaa ttctggcgcg ttgcgcccgt agttcgctga cgctcacacg
    29281 cgcagtacag cgccccgtcc tgttgcgacg caccagggcg gggtaaactc gcttgcgctc
    29341 gcgctaactg cggcattctg cggcgcaaat cagcataatc atggcctgct ggtcagttgg
    29401 gctttgcagg gtgaagggat ggcctgtgca ccctggtacg ttcgtcagcg gctgcgccgc
    29461 gcttcggggc gatgtggctc ctgtgctgcc ctggtatttt cgttcgcccc ttccatccgc
    29521 ttacgcggat taaaaaacgt gataacaatc acttatcgag taaaaaaacg ggagaaaact
    29581 tgcaaatgcg acttaagagt cgtatgattg tttcatcgaa aggggaatgg cccctctcac
    29641 aatagcccag cagggcagga gatttaaaaa atgaatatcc aggaagcatt aaacgttttt
    29701 ggattatccg gcgaattaac tgaaaaagat atcaaagcag catacagaaa agccgcttta
    29761 aaatatcatc cagatcgtaa cccgttaggg gctgaactga tgaaagcggt aaatgcagct
    29821 tttgatgtat tgatggcaaa tattgataaa ataaatcagt tccagagcac cgatgaacat
    29881 gcacgatata attacggtga tgacctggaa aaagtattaa acgttctttc tggtttatct
    29941 ggtctggtat ttgaagtgat aggtaactgg gtctggatta gtggagaaac cattacacat
    30001 aaggaaactt taaaagaaat cgggtgtaaa tgggcggcaa agaaaaaaca atggttttat
    30061 cgtccagacg aacataaaag ttactggaat cgtgaagaac acacgataga agaaatccgc
    30121 gcaaaatacg gtacaaccgg acagcgcagg gcgacagggt ggcaacgcgt ggaaaccaga
    30181 gcgtaaccag aacgggggca agaagccccc gatattatag ccagcccgtc ttttggggca
    30241 tcgaacccaa aaagacggga acagcagcca cgtagcaaaa agggatacag atgaactctt
    30301 tttttgaaca atatcaccct gtctttgaag ttgtctgccg tatcctgggg aacggctggc
    30361 gcgtgaacaa acttgatgat tgttcgtctc gtataaaact gacgtcaccg cagtttaaaa
    30421 attactctgt gcatattcgg atggaaaaag accggttttc tgttgtgggg agtgtggata
    30481 gtcgctcctg gcgtagtccg catcatgttt gcacgttatc cagaaaacgg aatcccgttg
    30541 atattgcagc cgatatcgag cgaaaaattc tggtaaatgc ttcgcaggag gtgttacagg
    30601 cgattgagta tgagaaacac caggtggaaa aaaaggacga aattctgatc ctgaaaggta
    30661 tgttatcgca acttgtccag cttgaaagct ggtatggggc attgacaggc tttaaagctg
    30721 aaaacggatt gaacggtaaa gtcaccgaac agggcgacag ttatgattta cagattcggg
    30781 gcttgagtat agatcaactt gttaaaatta cagggtattt gaaacagtta tgagaaaaaa
    30841 taaaggtgat gtgacttatt ttcttgaaaa agaaggtgac aattacagac ttacaaaaag
    30901 gataaaagcc agaacaaatg ttaaaatcgg gaacaaaact acgaaaatta cattgtatga
    30961 tgccgtactg aatgagaatg aattacaaca tattgatttt acgtgtgccg gattaaggga
    31021 agacgatgag acgccagtta agaatttaat taaggagttt atgttaaatg aaacccgata
    31081 atacacctga aaatgtaaaa aaattacgtt taaaagcagg attaacacaa aaggaatgca
    31141 gtcatattta tggtgttggg ctaagaacct ggcagaaaaa agaggaagtt aatactcaaa
    31201 acagtcaaag tctgtcactg gttgagtttg agtttctttt gttacttgca ggagaacatc
    31261 ctgaatacgt gctctgcaaa aggcagtcaa aataaaatga cctgtgatgg ttttatatta
    31321 gttcctggag ttgcgcccgt agttcgctga cgctcacacg cgcagtacag cgccccgtcc
    31381 tgttgcgacg caccagggcg gggtaaactc gcttgcgctc gcgctaactg cggcattctg
    31441 cggcgcaaat cagcataatc atggcctgct ggtcagttgg gctttgcagg gtgaagggat
    31501 ggcctgtgca ccctggtacg ttcgtcagcg gctgcgccgc gcttcggggc gatgtggctc
    31561 ctgtgctgcc ctggtatttt cgttcgcccc ttccatccgc ttacgcggat taaaaaacgt
    31621 gataacaatc acttatcgag taaaaaaacg ggagaaaact tgcaaatgcg acttaagagt
    31681 cgtatgattg tttcatcgaa aggggaatgg cccttctcac aatagcccag cagggcagga
    31741 gatttaaaat gaaatgctca tctgttttta cttcaaccac taatcatgtt ttcacattcg
    31801 aacgagtaac gctttgcact attatcctta tgcataagga tacgggacaa cagtatgttg
    31861 tcatatttac tgataacaat aaaattcgtg actataaaat tggaattgtt cctcagtttg
    31921 gcgaacttaa gcagagtgat gttgatttag tccttttcta cagggacgaa tatgaaaaat
    31981 attttgattc gttaaaagat ggcgatgaat gcttgagttt taaagatttt attgagtgcc
    32041 ttcgttaagc attataaatg caggggggga accctgcatt ttctggaaat ttcaatattg
    32101 attctgaaat tgtctattaa catcaatgca agggaaattc atgaaaacgt taaaacaagc
    32161 cacaatgcag tttgcatctg atctgcgtaa taatcgctgt tttaaagctg cttataatga
    32221 tgctctgtta gagcttgatc gggaagattt aaacgccatt gtacaatgca catttctttt
    32281 tgagccaaaa cgaacattag ccgaacttga taaattaatt aaaaagatag aagtagaaga
    32341 agattatgag ttttgtgtat cccttgataa aggtaaagga tggcacgaag tcagaacatt
    32401 taaaagtgag cgtgaggcgt tggatgctta tcgcattttg actctttacg gatacacagt
    32461 aactatagaa aagaaggagg gtaatgactg actattcaag gtgtgatcag gttgttccac
    32521 caacctgatc acgttatcga caatcaaaac tgaatgaggt ttttaaatgt caacgcggca
    32581 gatcgtacag cttgctgatt cccttgtcaa aggctgggaa accagaattc cggcaatgaa
    32641 atttagtgaa tgggatcaat tccggtggtg gttaaactac ttgcaagggt atgaaatgtt
    32701 ttaaataaaa aaaggggctt tctgcccctt tgtatttttt gactaaaatg ccatgtgtaa
    32761 ctatatggag gatggaaagg aacctgatac cccgtttaaa ggcgtgttta acgtcaggct
    32821 tgatccagaa ctgcatcgtc gggtagcaga aatggcgatg gaagaagatt tatcgttgaa
    32881 tgcctttgtt aataaggctc tggaaaaaga agtcagtaat catcgtgcag gggcttaatt
    32941 gcccttgttt ttttatgccc tgtaagggca tgggaggcgc tttgcgccgg aagccccgca
    33001 gcgcagcgag gacttaaaaa gcgttacgac ttcagccgta acaattccca gccctgccag
    33061 gcctgttttt tctttcacaa atctttcagc tatacgtttg ccagatggtc gaagacgaaa
    33121 gaacctttca gcaacgaaat ctggacatat gcagcgacga ttttatagcc aggcacagtg
    33181 ccacatatgg tacaatcaat gcaggataga caatcatggt caaaatgtta acattttatc
    33241 catgattgtc caaaaacgat gtttttgcct gtgcctgccg caggctct
//
