LOCUS       NZ_CP026424            18295 bp    DNA     circular CON 05-JAN-2024
DEFINITION  Acinetobacter sp. ACNIH1 plasmid pACI-148e, complete sequence.
ACCESSION   NZ_CP026424
VERSION     NZ_CP026424.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN03455971
            Assembly: GCF_002934695.1
KEYWORDS    RefSeq.
SOURCE      Acinetobacter sp. ACNIH1
  ORGANISM  Acinetobacter sp. ACNIH1
            Bacteria; Pseudomonadota; Gammaproteobacteria; Moraxellales;
            Moraxellaceae; Acinetobacter.
REFERENCE   1  (bases 1 to 18295)
  AUTHORS   Weingarten,R.A., Johnson,R.C., Conlan,S., Ramsburg,A.M.,
            Dekker,J.P., Lau,A.F., Khil,P., Odom,R.T., Deming,C., Park,M.,
            Thomas,P.J., NISC Comparative Sequencing Program,C., Henderson,D.K.,
            Palmore,T.N., Segre,J.A. and Frank,K.M.
  TITLE     Genomic Analysis of Hospital Plumbing Reveals Diverse Reservoir of
            Bacterial Plasmids Conferring Carbapenem Resistance
  JOURNAL   MBio (2018) In press
REFERENCE   2  (bases 1 to 18295)
  AUTHORS   Segre,J.A. and Mullikin,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2018) NISC, NIH, 5625 Fishers Lane, Rockville, MD
            20852, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 110x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/04/2024 13:28:28
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,625
            CDSs (total)                      :: 3,512
            Genes (coding)                    :: 3,284
            CDSs (with protein)               :: 3,284
            Genes (RNA)                       :: 113
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 88
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 228
            CDSs (without protein)            :: 228
            Pseudo Genes (ambiguous residues) :: 0 of 228
            Pseudo Genes (frameshifted)       :: 91 of 228
            Pseudo Genes (incomplete)         :: 141 of 228
            Pseudo Genes (internal stop)      :: 76 of 228
            Pseudo Genes (multiple problems)  :: 75 of 228
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP026424.1.
            Bacteria available from Karen Frank, Department of Laboratory
            Medicine, National Institutes of Health Clinical Center.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..18295
                     /organism="Acinetobacter sp. ACNIH1"
                     /mol_type="genomic DNA"
                     /strain="ACNIH1"
                     /db_xref="taxon:1636603"
                     /plasmid="pACI-148e"
                     /geo_loc_name="USA"
                     /lat_lon="38.984652 N 77.094709 W"
                     /collection_date="2014"
     gene            join(17939..18295,1..1523)
                     /locus_tag="C3F22_RS16415"
                     /old_locus_tag="C3F22_16425"
                     /pseudo=""
     CDS             join(17939..18295,1..1523)
                     /locus_tag="C3F22_RS16415"
                     /old_locus_tag="C3F22_16425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003653920.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter Kup"
                     /name="potassium transporter Kup"
     gene            complement(1590..1787)
                     /locus_tag="C3F22_RS16420"
                     /old_locus_tag="C3F22_16430"
     CDS             complement(1590..1787)
                     /locus_tag="C3F22_RS16420"
                     /old_locus_tag="C3F22_16430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005265040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004282105.1"
                     /translation="MFNFKIFNKVSTEVLTIKNDLQLNSEIQLITKYKTSTSEDYKKAI
                     ILIFKERGYSALEIGQLLEN"
                     /name="hypothetical protein"
     gene            2326..2775
                     /locus_tag="C3F22_RS16425"
                     /old_locus_tag="C3F22_16435"
     CDS             2326..2775
                     /locus_tag="C3F22_RS16425"
                     /old_locus_tag="C3F22_16435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005102339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BLUF domain-containing protein"
                     /protein_id="WP_005102339.1"
                     /translation="MNDFRLLYVSKIKSNINPVNDLYDILTEAVAFNSLNEIYGVLYYG
                     NDYFIQCVEGQKDKVEYLFYEKILKDPRHKNCEVLSFENIEKYLFSAWHMKYAMIHKEV
                     IDFFKHYHNDEFNPYLLNSSTIPAFIELLSTHGDSFSILKSKALT"
                     /name="BLUF domain-containing protein"
     gene            2925..3308
                     /locus_tag="C3F22_RS16430"
                     /old_locus_tag="C3F22_16440"
     CDS             2925..3308
                     /locus_tag="C3F22_RS16430"
                     /old_locus_tag="C3F22_16440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002011209.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0004803 - transposase activity [Evidence IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="WP_001055585.1"
                     /translation="MNMDIYSATPPVAKKRRKYSKEFKLSIVNACKNPNTSIASVALQH
                     SINANLVSRWIRIFSHHEGAVQDPTHVNPAFIALPYTAAISQPIDERITLCITVPHTNN
                     DIQLKWQTSEIPALAELLKALAT"
                     /name="transposase"
     gene            3305..3640
                     /gene="tnpB"
                     /locus_tag="C3F22_RS16435"
                     /old_locus_tag="C3F22_16445"
     CDS             3305..3640
                     /gene="tnpB"
                     /locus_tag="C3F22_RS16435"
                     /old_locus_tag="C3F22_16445"
                     /inference="COORDINATES: protein motif:HMM:NF017528.4"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="WP_000618091.1"
                     /translation="MIRIDEIWLSTQPMDMRAGMDTTMAQVVRAFGYIKPHCAYLFCNK
                     RGHRMKVLVHDGLGIWLCARRLEQGKFHWAQVHQGETVALSPEQLQALIQGLPWQRIGR
                     QQVVTML"
                     /name="tnpB"
     gene            3715..5298
                     /locus_tag="C3F22_RS16440"
                     /old_locus_tag="C3F22_16450"
     CDS             3715..5298
                     /locus_tag="C3F22_RS16440"
                     /old_locus_tag="C3F22_16450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005080579.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66-like element ISAba25 family transposase"
                     /protein_id="WP_005080957.1"
                     /translation="MNTLPDLSQLTHEQLLEFTRQLALQHQSLAQSNQQLDAKVQHLSI
                     LNQKYEHELALFKKHKFAQKNEHLTAKQIHLWDEAVEEDIAAVDLELERLNADKTNAAT
                     QKAKTNKPKRRPLPDHLHTIRIEHEPASTQCACGCQLRRIGEDVSEKLHFRPAQFYKEQ
                     HVRGKWVCDQCDTLTQQAMPAYVIDKGIASPELLSHVLVSKYADHLPLYRQRLIYQRAG
                     IDLSRSTLSDWIGRCGVELEPLANALKEVVLQQRVLHADETPVTIMRMGENNKKPKKGY
                     VWAYATTQYNPVQAVIYDFQDSRSGQHAEEFLKGWQGYLVCDDYSGYKARFKSGQVIEV
                     GCMAHARRKFHELHVTGKSQVAEQALVLIQKLYAIEAELRKKTDGTAEDRREYRQQHSQ
                     PVMQQLYEWLNQHHLTVPSSSPTAKAINYTLKRWPALSRYLDDGNLPICNNWVENQMRP
                     WALGRKNWLFAGSLRSGQRAANIMTLIQSAKLNGLDPYAYLSDVLKRLPTHKVTQIEEL
                     LPHCWKPKSN"
                     /name="IS66-like element ISAba25 family transposase"
     gene            complement(5601..5825)
                     /locus_tag="C3F22_RS16445"
                     /old_locus_tag="C3F22_16455"
     CDS             complement(5601..5825)
                     /locus_tag="C3F22_RS16445"
                     /old_locus_tag="C3F22_16455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004676219.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_004676219.1"
                     /translation="MPYEEFQRLMGKAGLSIKEFATLLDMNPNSITNYKKIGKVPTHIA
                     VLVYLLSSMKDEGVDFYPIFEKIKSYSKD"
                     /name="helix-turn-helix transcriptional regulator"
     gene            5975..6220
                     /locus_tag="C3F22_RS16450"
                     /old_locus_tag="C3F22_16460"
     CDS             5975..6220
                     /locus_tag="C3F22_RS16450"
                     /old_locus_tag="C3F22_16460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005249014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004282220.1"
                     /translation="MYSYPDSNTEKKIALMIINDFFIQKAHELWIFLQLDQCFNDYEAT
                     LIWTRRYLEKHPECEYSDIQKAFVSCFPEHFFSFDC"
                     /name="hypothetical protein"
     gene            6965..8191
                     /locus_tag="C3F22_RS16455"
                     /old_locus_tag="C3F22_16465"
     CDS             6965..8191
                     /locus_tag="C3F22_RS16455"
                     /old_locus_tag="C3F22_16465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005102330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /protein_id="WP_104427052.1"
                     /translation="MSDKIIIRNQYSCRISAIKKSNGHSPLRAIAYIQARKMQNSFSGD
                     EHNFSNKKGVIDAGFLMPLGIETGMNEEQFYNHLENNSHASTNILAYSSIMSLPSELDI
                     NNQKKLVEDFCKYFTDTYQTAVSFAIHEPDNKKKKRAKLEEIEKHNLPSDDDDLRMQMQ
                     NNHVHLVIPYCKISALTESDLTAKRKKKAIADTFKLGNQVKDFNPIKFGSEIKKDKPDL
                     MNTQQNFLQFMRQEWCRFINNSLELNNRIERYTHKSYKDLGLQISATVHEGEARKNILA
                     SGQKTAVNEYNKRQKAKQQTEADYLNFINVPLPFELANKILSGQKLAEKELLNSLKPPT
                     QTAEDPKPGPPELREKLDRLKSTNSPGPTPGHESLQQKLDRLKQKQADPPTPLAEPKQQ
                     DNDNDYSPF"
                     /name="MobA/MobL family protein"
     gene            8215..9366
                     /locus_tag="C3F22_RS16460"
                     /old_locus_tag="C3F22_16470"
     CDS             8215..9366
                     /locus_tag="C3F22_RS16460"
                     /old_locus_tag="C3F22_16470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017397930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_104427053.1"
                     /translation="MTASNETIDLLTAIVCTIESSDEKAQIAKSELLEQLKLLTSKTDV
                     ISTNFPKLIETLSTFDNKIASSFSNIENIDKRLSTVTNQIKSIENSVLNTQQQSKNLQL
                     DHIIEKLSNADQQAQQLSNHLRNSSTKYLENMNAATNIARKKIEELETEVANIADSFSK
                     IVSTRIADNVVTDVSSRLKNHVFRETVTGIEIGANEVAQTLTNKAFKNIDSTLKHTEKT
                     ILNDLHSFKKETDTAHQNWMQNIKKQQAEAEAIAKESHTMHMQREKTYQEHVSKEKAIV
                     KRNWILIILVAWFGFTGTALCIAYAVKSASEKTVDDALNYLTLRNNLTQLGFSVENKEF
                     CQSLLPKKQFNFTQGPQVSSCFYLESPAYEYTVNSRNLMIFTK"
                     /name="hypothetical protein"
     gene            10218..11216
                     /locus_tag="C3F22_RS16465"
                     /old_locus_tag="C3F22_16475"
     CDS             10218..11216
                     /locus_tag="C3F22_RS16465"
                     /old_locus_tag="C3F22_16475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004779643.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_026056584.1"
                     /translation="MAISLKKIKNFEEHDKSFFPLSAPAKRYPKDFAVFQNIFWQLKHE
                     RSPKDDILKLLFLFSPKVRLASDPNETTEFTVTAKEYAELTGLKLNSAYVALERVVDAL
                     YEHSVIFYHPEKDREIRTRLISTCSYKDGCFYIGFTHFALYIMYVFNKQNSYTKFKVKS
                     AVALHGHGLKLYPFLIQNEFRSNFDVSIRELKSALGLAENSYPEYRDFKTTILKPHIDA
                     INAKTELTVEFKALKKEGRKASHVNFIVRKKKTIKTEQQDEIGNNQIRSKVTAKMVYLT
                     IIQSEELSLRLKQSNETTDELVERVKNDFKNNEGSRWIEKLAEFNVRFETH"
                     /name="replication initiation protein"
     gene            11338..11856
                     /locus_tag="C3F22_RS16470"
                     /old_locus_tag="C3F22_16480"
     CDS             11338..11856
                     /locus_tag="C3F22_RS16470"
                     /old_locus_tag="C3F22_16480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017397202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid replication DNA-binding protein"
                     /protein_id="WP_004779644.1"
                     /translation="MKTLTVLELSKLYNINRQTIYNNIKKGILSKNSDNKIDLAEAIRV
                     FGEPNKKHDVKESVKVDSPNSAEVLLLRQQIDMLKNQLDDAKDRESFYQNQIETMQRLL
                     EAPKPHITQSGDHGSVQPEPATEAKEEVIAMPPKEPEVIENKRIPVPEHVEPEPEKRGF
                     WSRFFRPYD"
                     /name="plasmid replication DNA-binding protein"
     gene            complement(12114..13091)
                     /locus_tag="C3F22_RS16475"
                     /old_locus_tag="C3F22_16485"
     CDS             complement(12114..13091)
                     /locus_tag="C3F22_RS16475"
                     /old_locus_tag="C3F22_16485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004761028.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerC family protein"
                     /protein_id="WP_004761028.1"
                     /translation="MDVLFSNFLDKPVWMWIFFILIVLVLLILDLGVFHRKVREIGVKE
                     SLALSAFYITLGLLFGAWVWWYLGPTAGINYVTGFVIEKSLAMDNIFVIAMIFSYFSIP
                     RIYQHRVLFWGIIGVIFLRAIMIGVGATLVSQFSWVLYIFAAFLIFTGIKMWLSVDKEY
                     EVGNSPILNFIKKRFRVTEQLHAEKFWVKKIDPKTNQLTWFMTPLFLALIMIEFVDLIF
                     AIDSVPAIFAITTDPFIVYTSNIFAILGLRALYFALSAMVDRFHYLKYALAVLLVFIGS
                     KIFIADGLGIAKIPPPVSLSITFIILFTGILYSLWKTKDQSTHR"
                     /name="TerC family protein"
     gene            complement(13395..13826)
                     /locus_tag="C3F22_RS16480"
                     /old_locus_tag="C3F22_16490"
     CDS             complement(13395..13826)
                     /locus_tag="C3F22_RS16480"
                     /old_locus_tag="C3F22_16490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005401805.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_000042163.1"
                     /translation="MSKNQLCLDEQLCFPIYAASNLIVKAYRPFLTPLGLTYPQYLVML
                     VLWEKECVSVGDLGQILHLDSGTLTPLLKRMETSGLINRSRDPNDERRVLISLKDKGRD
                     LSAEAEKIPKELTKNIEFDNLNQLRDELKVLVNLLSERI"
                     /name="MarR family transcriptional regulator"
     gene            complement(13833..14261)
                     /locus_tag="C3F22_RS16485"
                     /old_locus_tag="C3F22_16495"
     CDS             complement(13833..14261)
                     /locus_tag="C3F22_RS16485"
                     /old_locus_tag="C3F22_16495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010116199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="WP_000105988.1"
                     /translation="MSTLYSTQVKAVGGRSGTIRSEDGILELKLALPKELGGKGDATNP
                     EQLFAAGYAACFGNAVIHVTRSNKEYKIRDNDVEVLSTVGIVANGNGGFALTVHLDVTL
                     SGISQADAEKIVEQTHQVCPYSNAIRGNIQVSTTVYTK"
                     /name="organic hydroperoxide resistance protein"
     gene            complement(14408..14710)
                     /locus_tag="C3F22_RS16490"
                     /old_locus_tag="C3F22_16500"
     CDS             complement(14408..14710)
                     /locus_tag="C3F22_RS16490"
                     /old_locus_tag="C3F22_16500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_001140620.1"
                     /translation="MAKTLQELLASRSPESQARIQKMADELLLENQLHLIREELEISQK
                     ELAETLGIKQPSLSAIENRGNDLKISTMKKYVEAMGGKLRIDVELPTGKHIGFNV"
                     /name="helix-turn-helix domain-containing protein"
     gene            complement(14703..15059)
                     /locus_tag="C3F22_RS16495"
                     /old_locus_tag="C3F22_16505"
     CDS             complement(14703..15059)
                     /locus_tag="C3F22_RS16495"
                     /old_locus_tag="C3F22_16505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005194067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_104427054.1"
                     /translation="MWTVITTDLFNEWLEQQDESTQEKVLAALVVLQQQGPSLGRPLVD
                     TVYDSKFTNMKELRVQHRGKPLRAFFAFDPLRQAIVLCIADKGSKKRFYKDMLDIADEQ
                     YQLHLTTLGDKSNG"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            15293..16864
                     /locus_tag="C3F22_RS16500"
                     /old_locus_tag="C3F22_16510"
     CDS             15293..16864
                     /locus_tag="C3F22_RS16500"
                     /old_locus_tag="C3F22_16510"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004780008.1"
                     /GO_function="GO:0052621 - diguanylate cyclase activity
                     [Evidence IEA]; GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor domain-containing diguanylate cyclase"
                     /protein_id="WP_104427056.1"
                     /translation="MKLFRFAEKKFNLNLRKLILFLSIFSVSSLFIISLVISYQIVKKQ
                     LINNSLSLNSQYANKIAMSTDNYFKNIAIELEYSAKILGKKYNNEEREAEVERLKMQSN
                     YYNSVVIGDPLGRLINYSPNILNIDKTKIQTTLGIRNSIKSKKFYISTPYRSIKNNMII
                     FISYPIFDEKKKYKGFIGSAIYLEEKNVINQLLTTTEGYRKSYMYVIDKNGQIIFHPDH
                     KRIGEIAKNNSGLEYIKQNKNGTTRLINSRGVDNLAGFAHIKTTDWIIISQQPTLELLT
                     QANSIIYKVSGGIFIFYLIIFYIVWKCSFYIASPLHKLASIAGSLDQSETSNEIKSIIP
                     WYYEIVKFKLSLLLSMRSFSLRINEMDYHINTDPLTGLMNRRGLNFTIEKKLSINSFFS
                     ILMIDVDFFKKINDTYGHEQGDLVLKCLAEIMQKNFRKNDVCCRYGGEEFIVLIPNVSK
                     EEAYESAERFRKAVEQQFIENVGYITISIGIAYWPESSEDISEVFRIADKHLYEAKISG
                     RNCIKF"
                     /name="sensor domain-containing diguanylate cyclase"
     gene            complement(16956..17567)
                     /locus_tag="C3F22_RS16505"
                     /old_locus_tag="C3F22_16515"
     CDS             complement(16956..17567)
                     /locus_tag="C3F22_RS16505"
                     /old_locus_tag="C3F22_16515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004889724.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_104427055.1"
                     /translation="MIEMNTRIYLRASTKDQDAERALQILQDLNQNLNLGETIVYVENY
                     SGTKLNRPELNKLLSEANQGDTLLVESIDRLSRLTQQDFQELKRRIQEKGLRLIVADLP
                     TTYQMIQTSDSITHSILELINNMLIDLLATMARLDNEKRIERIKQGLERSGYKPTGKKA
                     NEAKHKRIKELLAAGNMTKEEIAKAVNCGVATVYRVAKVI"
                     /name="recombinase family protein"
     Typing          10219..11216
                     /name="rep_cluster_1041"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 acggtatcat cacccctgct atttctgttt tatctgcagt tgagggactt tctgttgctg
       61 ccccgtcatt tgatcgcttc attattccaa tcagtattgg aattcttata gctctctttg
      121 ccgttcaaaa acatgggact gcaatgatgg ggaagttttt tggtcctatt accctgttat
      181 ggttcctatc tattggtgcc attggcatta taagtattat tcaaagtcca tttgttcttg
      241 cattattcag cccacactgg gcttttttat tcgttattaa caatcctctt atttcatttt
      301 ttgtaatggg agctgtggtt ttaacagtaa caggtggtga agccttatat gcggatatgg
      361 gacattttgg tattttaccg atcaagttag gctggttttt aattgtactg ccatgtctga
      421 tgctgaatta tgctggacaa ggagcgttac tgttaagaga tccttcggct atcaccaatc
      481 ctttttacct gcttctgcct tcagcccttc tatatcctat gattattctg gctactgcag
      541 ctgcagtgat tgcctcacag gctttaatca gtggggtatt ctctatggct aaacaggcaa
      601 tacagttggg atatctacct aggcttacag ttttacatac ctccgcttcg gaaattggac
      661 aaatttatat tccattactg aactggctcc tgtttatctc tatcaccatc ttgatcttaa
      721 tatttgaaag tagcagcaag ttggcaggtg cttatggtct ggccgtcact gtgaccatgt
      781 tctgtgacac actgttagta gcttttctgg cttatagtta ctggaaatgg aaaacatgga
      841 aagtcttact gttcattatt ccattcgcct ttattgatct ggttttgctg agttcaaacc
      901 tattaaaagt cctgattgga ggctgggtac cagtcgttat tgcggttatt gtttttaccc
      961 tcatgatgac ctggaaaaaa ggcagagaga ttcttcagga caaactgcag aaggacacgc
     1021 ttccactgaa tgtgtttctt gagcaccttg aacagacagg tcagaaagtg agtggaaatg
     1081 ctgtattttt aactggaacg cctcaagtcg taccccatgc gcttttacat aatctaaagc
     1141 ataataaagt tctgcatgaa cgtaattttt tggtgacaat caagacttct gaaatcccgt
     1201 atgttgatga agctaagcga atcgttactg aagtactaga gaatggtttt ttcagaataa
     1261 cgatccatta tggatttaaa gaagagccta atgtgcctca ttcattgaaa caagcttttt
     1321 cagtactgga tcttgagtat gacttaatga atatcagctt ctttgtttct agagaaagat
     1381 taattccaag tctgtccagc aagatgtcta catggcgtga aaagttattt gtcgcaatgc
     1441 aaaaaaatac cagccctgtc agtgattttt ataaaatccc ttctaaccgg gtggtagagc
     1501 taggtagtca gattgaaatt taagaatttc taaaatgaat aggcaccttt aaataagggt
     1561 gcctatctga tcagaataaa tcttttactt taattttcca atagttgacc aatctctaaa
     1621 gctgaataac cacgttcttt aaagatcaaa ataattgctt ttttataatc ttcagaagta
     1681 gaggtcttat attttgttat aagttgaatt tcagaattaa gctgaaggtc attttttatc
     1741 gtcaacactt ccgtagagac tttattaaaa atcttgaaat taaacataca ggcgctcttt
     1801 atcaatatta tagcggcccg actacaacaa atacctgcct tagctcagct agacaccctt
     1861 ggctgcaagg attacaaatt agacaagatt ctgcaagttt tgctccattg aaagtatgaa
     1921 tattcaacta aagaaggttc catttaacat aatggcgatt atacgcaata cacttgtata
     1981 ttaatttaaa tatcaattac ttaataaaaa cagaaaaatc caaaaatgcc caaaaatccg
     2041 attttgaaac aagtcggctt ttttatgagc agttttgata gttcttgcca ataaatttgt
     2101 ttaaaaagta gtcgattttg cgatttttta aattttatca atgcttgaat gcttaaaatt
     2161 atccacattt tttgtggata aaatttaggc tattttgtac gctttggctc atgcattagc
     2221 ttgtatattt atttggctac ctttatcggg taaattctat acttgaaatg tcaacagacc
     2281 ctaatcgtat taaaaatttt taaaattttc attaaggcaa aagctatgaa tgactttaga
     2341 ctactatatg taagtaagat caaaagtaat attaatccgg taaatgatct atatgatatt
     2401 ttgacagaag ccgtagcttt taatagccta aatgaaattt atggtgttct ttattatgga
     2461 aacgattact ttattcaatg cgtagaaggt cagaaagata aagtagaata tctattttat
     2521 gaaaaaattt taaaagatcc acgtcataaa aactgtgaag ttttatcttt cgaaaatatc
     2581 gaaaaatatt tattttctgc atggcatatg aaatatgcca tgattcataa agaagttatt
     2641 gatttcttta agcattatca taatgatgaa tttaatcctt atttactgaa tagctctact
     2701 attccagctt ttatagagct gttaagcaca catggagata gcttttctat cttaaaaagt
     2761 aaagctttaa cttaaccagt acaaaaatta tttagaataa aattaatata ataaagtgct
     2821 ttcaaaagac ttatgaatgt aagcatccgg ctaacacagc cttaccaagc gatcctataa
     2881 gccttaattt agttcccacc taaaaacaag tggggactta atccatgaac atggatatat
     2941 attcagcaac acctcctgtt gctaaaaaac gccgaaaata cagcaaagaa ttcaaactca
     3001 gtattgtcaa tgcctgcaaa aatcctaata cctcgatcgc ttcggtcgca ctgcaacata
     3061 gtattaatgc caaccttgtc agtcgttgga tcaggatctt cagccatcat gagggtgccg
     3121 tgcaggatcc tactcatgtg aatccagcat ttattgcttt gccttacact gctgcaatca
     3181 gccaacctat tgatgagagg atcacgttgt gtatcaccgt gcctcatacg aataatgata
     3241 ttcagctaaa atggcagaca tcagaaatac ctgccttggc agaattactc aaggcacttg
     3301 caacatgatc cgcattgatg aaatctggtt gtctactcag cccatggaca tgcgtgcagg
     3361 tatggatacg accatggctc aggtggtgag agcctttggc tacatcaaac cgcattgtgc
     3421 ttacctgttc tgtaataaac gtggccatcg catgaaagtg ctggtacatg atggattggg
     3481 catctggctg tgtgcccggc ggctggaaca gggcaaattt cactgggctc aagttcacca
     3541 aggtgaaacc gtggccctca gcccggaaca gttacaggca ctgatccaag gtttgccctg
     3601 gcagcgcatt ggacgacagc aggtggtgac gatgctttaa accaggctcg accattctgc
     3661 tattctccaa acgttctatt tcattcttct catgacctca ggcatactgc ggtcatgaat
     3721 acgctgcctg acttaagcca actgacccat gaacaactgc tggaattcac caggcagttg
     3781 gcgctgcagc atcagtctct agcacaatca aaccaacaat tggatgccaa agttcaacat
     3841 ctttctattc tcaatcaaaa atacgagcat gaactggcgc tgtttaaaaa gcacaaattc
     3901 gcccaaaaga atgaacactt aacggcaaaa caaatccatc tctgggatga agcggttgaa
     3961 gaagatattg ccgcggttga tctagaactg gaacggctaa atgcagataa aaccaatgca
     4021 gcgacacaga aagccaaaac caataaacct aaacgtcgac cactgccaga tcatctacac
     4081 accatccgta ttgagcatga acctgcatca acccaatgtg cttgtggctg ccaactccgt
     4141 cgtatcggcg aagatgtcag tgaaaaactg catttcagac cggcacagtt ctataaggaa
     4201 cagcatgtgc gtggtaaatg ggtctgtgat cagtgtgaca ctctaactca gcaagcgatg
     4261 cccgcctatg tgattgataa aggcattgct tcacctgaat tgctcagcca tgtgctggta
     4321 tcgaagtatg ccgatcattt gccgctgtac cgtcagcgcc tgatctatca gcgggctggc
     4381 attgatctgt ccagatccac tttatctgac tggataggtc gctgcggtgt agaactggaa
     4441 cctctggcca atgccttaaa agaggtggtg ctgcaacagc gggtgctgca tgcagatgaa
     4501 acaccggtca ccatcatgcg gatgggtgag aataataaaa aaccgaagaa aggttatgtc
     4561 tgggcctatg ccaccacaca gtataatcca gttcaggcgg tgatctatga ctttcaggat
     4621 agtcgttcag gccagcatgc tgaagagttc ttgaaaggct ggcagggcta tctagtctgt
     4681 gatgattaca gtggttataa agcacgtttt aaatcaggcc aggtgattga ggtggggtgc
     4741 atggcccatg cacgtcgtaa attccatgaa ctgcatgtaa ctgggaaaag tcaggttgct
     4801 gaacaggcct tagtgctgat tcagaaactg tatgcgatag aagcagaact caggaaaaag
     4861 accgatggta cagcggaaga ccgccgcgaa taccgacaac agcatagtca accagtgatg
     4921 caacaactat atgaatggct caaccaacat catctgacag tgccatcgag ttctcccacc
     4981 gccaaggcta tcaattacac tctgaagcgt tggccagcct taagccgcta tctggatgat
     5041 ggcaatctac cgatatgcaa caattgggta gagaatcaga tgcgtccctg ggcgttggga
     5101 cgcaagaact ggctgtttgc aggttcgctg cgcagtggtc agcgagcggc aaacatcatg
     5161 actttaatcc agtcagcaaa gctgaatggc ttggatccgt atgcctattt aagtgatgtg
     5221 ctgaaaaggt taccgacaca caaagtgacc caaattgaag aattgctgcc gcactgctgg
     5281 aaacctaaat cgaattaaaa aataggtatg ggattcagcg gacgcttact tatgaattaa
     5341 gtcttttgat catgcattta acataaaatc tcttatacgc aattcagttg taacccccaa
     5401 atagaaatgt ccggtttacc gattgctcga cctaagatat cagaatataa gaatttgatg
     5461 atcaccctgg ttctcaaaac tcgatacttt attgaaaagt tctatcgagg cttataagtc
     5521 cctgaaacaa aaaaatgcct gaacttcagg cattttttac gtcatcacta acagcttaca
     5581 acaatcaaca aacgagagtt ttagtctttt gaatacgact taattttttc aaaaataggg
     5641 taaaagtcta caccctcatc tttcatgcta gaaagtaagt aaaccagaac agcgatatga
     5701 gtaggtactt ttccgatctt tttatagtta gttatggagt ttgggttcat gtccaataag
     5761 gttgcaaatt ccttaattga aagacctgct ttccccataa gtctttgaaa ttcttcgtat
     5821 ggcatcgtga taaatacaat ctgtttgaat tagaagtata acacagacca taaaacttaa
     5881 aaaaacacat aaaaaatgtg acaaacacat tttttatgtg ttataaatag cttatcagct
     5941 aacccattta tccttattat cggagaaata taatatgtac tcatacccgg attcaaacac
     6001 tgaaaagaaa attgctctca tgatcatcaa tgactttttc attcaaaaag cccatgaact
     6061 gtggattttt ttacaactcg atcagtgctt taatgattat gaagccacac tgatttggac
     6121 tcgacgttat ttagagaagc atcctgagtg tgagtacagc gatattcaaa aagcctttgt
     6181 ttcttgtttc ccagaacact tcttcagctt tgactgttaa tttatgagag gcacggtaaa
     6241 aaatcgcaat gggtaagtaa atcccaaata gaaagagccg gttcatacaa ctggcttttt
     6301 attgtcacgt ataaatctaa gactttcttt gagcatacta aaattgatgt tccacggctt
     6361 ctaagacatt gattttaggt tcaagattgg ggccgccatg acgttacttt agggtgtact
     6421 ttaaagatac aaaaataaaa acttataaaa tacgataagt cagttaaatg atgcataaaa
     6481 tttgatttga gtccctaagt ctttcacttt ctcattattg aaatgatact gtaaaaaaga
     6541 ttttgtctta gtattcatca agacacattt agagtaatca atattcatat tactatcacg
     6601 gaaaaaacaa ttaattgaaa ttatcacaag tgaaaaaaat cgaaaaataa caccaaatac
     6661 aggtcagttt tttttgtagt gtatagtcga attacgtgac aacttcattc acgacatttc
     6721 acgtttttac agtcaagcgc aagcgtagac tgtaaaaacg tagaaatgac gtagaatgaa
     6781 gcgcacttta acccaaaacg cacatttcgc ttcgctcatg ttcgttttga gtcgtgcgcc
     6841 cccctaaaaa accagggaag gggggggact tttaaacctt ttttctgatc taaaaatcat
     6901 tgtgctttgc caattttttt atgtcagcta atgtcttaaa agtacaaagc aaaagcgcaa
     6961 aagcatgtct gataaaatca ttattcgtaa tcaatattct tgccggattt ctgcaatcaa
     7021 aaaatccaat ggtcatagcc cattgcgagc tattgcatat attcaagcac gaaaaatgca
     7081 aaacagtttc agtggtgatg aacataattt ttctaataaa aagggcgtga ttgatgcagg
     7141 ttttttaatg cctttaggca ttgaaacagg aatgaacgaa gaacaatttt ataatcattt
     7201 agagaacaac tctcacgcat caacaaacat tcttgcatat tcgtcaatca tgtcattgcc
     7261 atcagaatta gatataaata atcaaaaaaa attagtcgaa gatttttgca aatatttcac
     7321 agacacatat caaacagcag ttagttttgc gattcacgaa cctgacaaca aaaaaaagaa
     7381 acgggcaaaa ctagaggaaa tcgaaaagca taatttgccg tctgatgatg acgatttgcg
     7441 tatgcaaatg cagaacaatc atgttcattt agtgattccg tactgcaaaa tttcagcact
     7501 cacagaaagc gacttaacag caaagcgtaa gaaaaaagcg attgctgaca cgttcaagct
     7561 cggcaaccaa gtgaaagatt ttaatccaat taaattcggc tcagagatca aaaaagacaa
     7621 acctgatttg atgaatacac agcaaaattt tttgcaattc atgcgtcaag agtggtgcag
     7681 atttattaat aattcgttag agctaaacaa cagaattgaa cgctatacac ataaatcata
     7741 taaagacctc ggattgcaga tttcagccac tgttcacgaa ggtgaagcac gaaaaaacat
     7801 tctagcaagc ggtcaaaaaa cggctgtgaa tgaatacaac aaacgtcaaa aagcaaagca
     7861 acaaacagag gcggattatc tcaattttat caatgtgcct ttgcctttcg agttagcaaa
     7921 taaaatcttg agcggtcaaa aacttgctga aaaagaatta ttaaacagtc tcaaaccacc
     7981 gacccaaacg gcagaagatc caaagcctgg cccacctgag ctgcgtgaaa aattagatcg
     8041 tctaaaatcc accaactccc ctggtcccac acccggacac gaatcattac aacaaaaatt
     8101 agatcgttta aagcaaaagc aagctgatcc accaactccc ctggccgagc cgaagcaaca
     8161 agacaacgac aacgattact caccctttta attattaata aataaggaag tcacatgact
     8221 gcaagtaacg aaactattga tcttttgact gcaattgtct gcacgattga aagctcagat
     8281 gaaaaagcac agatagctaa atcagagcta ctagaacaat tgaaattact tacatcaaag
     8341 accgatgtaa tcagcacaaa ttttccaaaa ttgatcgaaa cgctatcaac tttcgacaac
     8401 aagattgcat cgagtttcag caatatcgag aacatcgaca agcgtttaag tacagtcact
     8461 aatcaaatca aatcaataga aaactcagtt cttaatactc agcaacaatc aaaaaattta
     8521 caactagatc acatcatcga aaagctcagt aatgcagatc aacaagcaca acagctaagc
     8581 aatcacttac gtaattcaag cacgaaatat ttagaaaata tgaatgcagc aacaaacatt
     8641 gcacgaaaaa aaatcgaaga attagaaaca gaagtagcaa acattgcaga tagtttttca
     8701 aaaatcgttt caacaagaat tgcagataat gtcgtcacag atgtttcatc acgattgaag
     8761 aatcatgttt tcagagaaac agtcacaggc attgaaatag gagcgaacga agtagctcaa
     8821 acacttacaa acaaagcgtt taaaaacatt gattcaacgc tcaaacacac tgaaaaaaca
     8881 atcttaaatg atctacattc attcaaaaaa gaaactgata cagcacatca aaattggatg
     8941 caaaacatca aaaaacaaca agcagaagca gaagcaatag cgaaagaatc acacacaatg
     9001 cacatgcaac gagaaaaaac gtatcaagag catgtcagca aagagaaagc gattgtaaaa
     9061 aggaactgga tattaattat attggtcgca tggttcggct ttactggaac agcattgtgt
     9121 attgcttatg cagtaaaaag tgcatctgaa aagacagtag atgatgctct aaactatctg
     9181 acattaagaa ataatctgac ccaactcggc ttttcagtag aaaacaaaga gttttgtcaa
     9241 agcctattgc caaaaaaaca gttcaatttt acccagggtc ctcaagtatc tagttgtttt
     9301 tatttagaaa gtccagcata tgaatatact gtgaacagtc gaaatctaat gattttcaca
     9361 aaataagaat caagccctcg tctgagggct tacttttgaa tctctaaaaa cgcacagaat
     9421 cactcagatt gaacgaagca atcaaaacgg tacattgaca ccaaagaaca ataaaaactc
     9481 aatgtggctc aaatggtgaa gaaacaaagc tatattcatc ctgtgtttta actaatgtcg
     9541 ttaataaatc aaaaaattac tattaatctc accgttatta agaatattta aacaatgaca
     9601 acaagttaca gagcgagtgt ctacgagcga acagttgtaa gtgaattttg ccgccacttt
     9661 ttccctgatt acaggctccc attattggtc taaacgggag atgaagagcg tcacgaagtg
     9721 cgcgaacgat ggagcttttg tttttccttt aatttacaac tgaattaagc aaaaaatcgc
     9781 ccctcagaat cgagcgaaag cgagattcaa tagagtttga gcatagcgaa aaccaagggc
     9841 aatttttatt tagatttatt ttaaaagctt tattaaaagc ttttaatagc ttttaaaaag
     9901 cttttaaaaa gctttacgga tagtatgaat gtattgatag ataaggcttt tagacatcaa
     9961 agtgggggtg gattgttagg tttttggctt aaagtggggg tggattgtta ggtttttggc
    10021 ttaaagtggg ggtggattgt taggttggtg ggggtggatt gttaggttgg tgggggtgga
    10081 ttgttaggtt ggtgggggtg gattgttagg ttggtggggg tggattgtta ggttatatga
    10141 attacttgac ttataaagtg ggggtaatta ttatcaagca acccccacat aatagtaata
    10201 atagtgactc cttctacatg gctatatcat taaagaaaat taagaatttt gaggaacatg
    10261 acaaatcttt ttttcctctt tcagcaccag ctaaacgtta cccaaaagat tttgctgtct
    10321 ttcaaaatat tttctggcaa ttaaaacatg agcggtctcc taaagatgat attttaaaat
    10381 tactgttctt attcagccca aaagttcgac tagcatcaga cccaaatgaa acaactgaat
    10441 ttactgtgac agctaaggaa tatgcggaat taacaggatt aaagctaaac agtgcttatg
    10501 tagcattaga gagagtcgta gatgctcttt atgaacatag tgttattttt tatcatcctg
    10561 aaaaagatag agaaattcgt acaagactca ttagtacatg ctcatataag gatggatgct
    10621 tttatattgg tttcacgcac tttgccctat acattatgta tgtttttaac aagcaaaatt
    10681 cgtatacaaa attcaaagtg aaatcagcag ttgccttaca tggccatggc ttaaaactct
    10741 atccattcct aatacaaaat gaatttcgct ctaattttga tgtttccatt agggaactaa
    10801 aaagtgcttt aggccttgct gaaaattcct accctgagta ccgagatttt aaaactacta
    10861 ttcttaaacc tcacattgat gcaattaacg cgaaaacaga acttactgtt gaatttaaag
    10921 ctcttaaaaa agagggacgt aaagctagtc atgttaattt tatagtgaga aaaaagaaga
    10981 ctataaaaac agaacaacaa gatgaaatcg gtaataacca aatacgatct aaagtcactg
    11041 caaaaatggt ttacttaacg ataattcaaa gtgaagaatt aagtttacgg cttaaacaat
    11101 ccaatgagac aacagatgaa ttagtcgaac gagtaaaaaa tgattttaag aataatgaag
    11161 gtagcagatg gatagaaaaa ttagcggaat ttaatgtgcg gtttgaaact cactaaaaca
    11221 tcataattta ttttaaaaat tatcatttac cttgcttaaa atttaaactt gatcatttgt
    11281 ctattagaca gtctaataga cactaacttt ttacaagttt aggcataggt ttacaggatg
    11341 aaaaccctta cggttcttga actttccaag ctttacaata ttaatagaca aactatttac
    11401 aacaacataa agaaaggaat tttaagcaaa aattctgata ataagattga tctagccgaa
    11461 gctatccgtg tatttgggga gcctaataaa aaacatgatg taaaagagtc tgtaaaagta
    11521 gacagtccaa attcggcaga agttttactg cttagacagc agatagacat gctgaaaaat
    11581 cagcttgatg atgccaaaga ccgcgagtct ttttatcaga atcaaattga aacgatgcaa
    11641 cgtctattgg aagcaccaaa accccatatc actcaatctg gtgatcatgg atcggtacag
    11701 ccagaaccag cgacagaagc aaaagaagag gttatagcaa tgccacctaa agaacctgaa
    11761 gtaatcgaga acaagcgcat tccagttcct gaacacgtag agcctgaacc ggaaaaaaga
    11821 gggttttgga gccgtttttt tagaccctat gattaaccac gattgtttaa ctaatatgaa
    11881 caaagtcgtg aaactttggt caaagaatag gcgtggaacg tgaaaaatca taaaaaaaac
    11941 ccaccttggg gaagatgggc tatcaactag aaactacagc attgatttct aagtggaatt
    12001 ataacgcatt tcgtataagg tgtattatgt taattttagg aaaacttata atcagaataa
    12061 ttaacagcca ctgttttatt ggtagctatt aattatttaa aggattgtaa tttttaccta
    12121 tgagtacttt gatcttttgt tttccaaaga gagtatagaa ttcctgtaaa caagatgatg
    12181 aacgtgatcg aaagggagac tggcggtgga atttttgcta tacctaatcc atcagctata
    12241 aaaatttttg atccaataaa gactaacaat actgctaatg cgtacttcaa ataatggaag
    12301 cggtcgacca ttgctgatag ggcaaaatat aaagcacgta atcccagaat tgcgaaaata
    12361 tttgaagtat aaacaataaa tggatctgtc gtaatcgcaa aaatcgcagg aacactatct
    12421 attgcaaaga tcagatctac aaattcaatc atgatcaagg ctagaaaaag tggtgtcata
    12481 aaccaggtta attggttagt ttttggatca atctttttca cccagaactt ctctgcatga
    12541 agctgctcag tgacacgaaa tcttttttta ataaagttca aaataggaga atttccgact
    12601 tcatattctt tatcaacact tagccacatt tttatccctg taaaaataag aaaggctgca
    12661 aatatataaa gaacccatga aaattggcta accagtgttg cgcccacgcc aatcatgata
    12721 gctcttagaa aaattacacc tataattccc caaaataaga ctctatgctg ataaattctt
    12781 ggtatcgaga aatatgaaaa aatcattgca atgacaaaga tattatccat cgctaatgat
    12841 ttttcaatta caaaaccggt tacatagtta atccctgccg tgggtccgag ataccaccac
    12901 acccatgcgc cgaaaagtaa acctaatgta atataaaatg ctgatagtgc taagctttct
    12961 ttaacaccaa tctctcttac cttacgatga aatactccaa gatctagaat aagcaggaca
    13021 agtacaataa ggataaagaa aatccacatc caaacaggtt tatctaaaaa attcgaaaat
    13081 agaacgtcca tagttttcct ctgcctatac ttgtgcttat atgagaagat atgctcatta
    13141 tcaataatac ttgtcaatat ttattacata taaagatata ttcagaattc ataaatcccc
    13201 catttaacat aatgggtgtt atacgaaata aaaaaaacta ggcacaggcc taggtcttaa
    13261 attttaaaaa aatataaaaa ttaatgatat agcctcagtt tttcaacttc atataacgtg
    13321 tattatgtta attttagaaa aactaattga ttcttgaaag taaacaggct tccattatca
    13381 gatattaaga ggtctcaaat tctttctgat aatagattaa ctaatacttt taattcatct
    13441 cgtaattgat ttaagttatc aaactcaatg ttcttggtaa gctctttagg aatcttttct
    13501 gcttcagcag ataagtctcg ccctttatct tttaatgaaa taagaactcg tctttcatca
    13561 ttaggatcac gtgatcgatt aattagacca gatgtctcca ttctttttaa tagtggggtt
    13621 aatgttccac tatcaagatg taaaatttgt ccaagatcac ccacacttac acattctttt
    13681 tcccacaaaa ccaacatcac taaatattga ggataagtga gtccgagagg tgtaagaaaa
    13741 gggcgataag cttttacgat taaattagat gcagcataaa taggaaaaca tagttgctca
    13801 tctaagcaaa gctgattctt ggacatagct ttttatttgg tatagacagt ggtagacacc
    13861 tgtatattac ctcgaatagc attggaataa ggacatactt gatgcgtttg ttccacgatt
    13921 ttctctgcat cagcttgtga aatacctgaa agcgtgacat ctaagtgtac tgtcaaggca
    13981 aatccaccat tgccattagc aactattcca acagtactca ggacctctac atcgttatca
    14041 cggattttat attctttatt gctacgagtt acatggatca ctgcatttcc aaagcatgca
    14101 gcatagccag ctgcaaataa ttgttcagga ttcgttgcat cacctttacc acctaattct
    14161 tttggcaaag ccaattttag ttctaagata ccatcttcac tacgaatcgt tcccgaacgt
    14221 ccaccgactg ctttgacttg agttgaatag agagtactca tgtatattac cttgcttaat
    14281 attatattgt gtaaaatata attgcacaca attaaatata ggtcaattat tttcctttgt
    14341 tttttattta acataatggc gattatacga atctaaaaat gggagtcttt agctcccatt
    14401 tttattgtta aacattgaat cctatatgtt ttcctgttgg aagctctaca tcaatacgga
    14461 gcttcccgcc cattgcctca acatactttt tcatggttga aatcttaaga tcattgccac
    14521 gattttctat tgctgaaagc gatggctgtt ttattcccaa agtttcagca agttcctttt
    14581 gagagatttc aagttcttca cgaataagat gaagctgatt ttctagcagt aattcatctg
    14641 ccattttttg aatacgggct tggctctctg gagagcggct agctaacaat tcttgcagag
    14701 tcttagccat tagatttatc tcctagggtg gtgagatgaa gttggtattg ttcatctgca
    14761 atatccagca tgtctttata aaaacgcttt ttactgcctt tatcagcaat acatagaaca
    14821 atagcctgtc gtaaaggatc aaatgcgaag aaagctctca gtggtttacc tcgatgttga
    14881 acacgaagct ctttcatgtt ggtaaattta gagtcataga cagtatctac taaagggcgg
    14941 cctaaacttg gtccttgctg ctgtagaaca actagggcag ccagaacctt ctcttgtgtt
    15001 gattcgtctt gctgttcaag ccattcatta aatagatctg tcgtaatgac tgtccacata
    15061 ccacaaccaa aatatagatt atagtctata ttttaggagc attatgcttg ttttgcaaat
    15121 gagaaatgat aggcaataaa aaaccccagc atcctgccgg ggtttttcat attgggttgc
    15181 ctattcattt tagatttata tgaataaaag taaaaaaaat aaatacacta ctttaactac
    15241 gaaagaaaag tgtaataaac ttaaccacat atgcctaatt aatcataaat acatgaaatt
    15301 atttagattt gctgaaaaaa aattcaattt aaacctaaga aaactaatac tttttttatc
    15361 gattttttct gtatctagtc tttttataat ttctttagtt attagctacc aaatagtaaa
    15421 aaaacaactt ataaacaatt cattatcatt aaattctcag tatgcaaata aaattgcgat
    15481 gagtacagac aattacttta aaaatattgc tatagaatta gaatatagtg caaaaatttt
    15541 agggaaaaaa tataataatg aagaacgtga agcagaagta gaacgtctca aaatgcaatc
    15601 taactattac aatagtgtag ttataggaga tccattaggt agattaatta actattctcc
    15661 taatattttg aatattgata aaaccaaaat acaaactaca ttaggaatta gaaactctat
    15721 aaagagtaaa aaattttata tttctacgcc atatcgctct attaaaaata atatgattat
    15781 ttttatatcg tatcctatat ttgatgaaaa gaaaaagtac aaaggcttta tcggatcagc
    15841 aatttattta gaagaaaaaa atgtgatcaa tcaactttta acaaccactg aaggctatag
    15901 aaaaagttac atgtatgtaa ttgataaaaa tggccaaata atttttcatc ctgatcacaa
    15961 aagaattggt gaaatagcta aaaataatag tggattggaa tatataaaac aaaacaaaaa
    16021 tgggacaact cgtcttatca atagccgagg agttgataac cttgcaggat ttgcacatat
    16081 caaaactact gattggatta ttatctctca acaacctaca ttagaacttc taactcaagc
    16141 aaattcaatt atttataagg tttcgggtgg gatttttata ttttatctaa ttatttttta
    16201 tattgtttgg aaatgctcat tttatatcgc atctccgttg cataaacttg cttctattgc
    16261 aggatcactt gaccaatcag aaacaagtaa tgaaattaaa agcattatcc cgtggtatta
    16321 tgagattgtt aaatttaagc tttcattatt attaagtatg agaagctttt cattaagaat
    16381 aaatgagatg gattaccata ttaatacgga tcctcttact ggtttaatga atcgtagagg
    16441 tttgaatttc actatagaga aaaaattaag tataaatagt tttttttcta ttttaatgat
    16501 agacgtagac ttttttaaaa aaataaacga tacatatgga catgagcaag gagatttagt
    16561 cctaaagtgc cttgcagaga ttatgcaaaa aaactttagg aaaaatgatg tttgctgccg
    16621 ttatggaggt gaagagttta ttgttctaat accaaacgta agtaaagagg aagcttatga
    16681 aagtgcagaa cggtttagaa aagcggtaga acaacaattt atagaaaatg taggctacat
    16741 tactatttct ataggtatag catattggcc agaaagctcc gaggacattt cagaagtctt
    16801 taggattgca gataagcatc tttatgaagc taaaattagt ggcagaaact gtataaaatt
    16861 ctaatttata ggcctgatat ttaacataaa atctcttatg tgaagcaatc tgaatgcagc
    16921 ggtgccccat tggggcgcgt tgagataagc ctcttttaga taactttagc aactcgatag
    16981 acagttgcaa ctccacaatt cactgctttg gcaatttctt ccttagtcat attgccagct
    17041 gctagcaatt cttttattcg tttgtgctta gcctcattgg ctttcttacc tgttggcttg
    17101 taacccgaac gttccaggcc ctgcttaata cgttctatac gtttctcatt gtctaggcgg
    17161 gccattgttg ccaggagatc aatcaacata ttgttgatga gttccaagat tgaatgagta
    17221 atgctgtcac tggtttgaat catttggtag gtagtaggaa gatctgccac aattaatcga
    17281 agtcctttct cctgaatcct gcgcttcagc tcttgaaaat cctgttgggt taggcgtgat
    17341 aatcggtcaa tactttcaac caacaaggtg tcaccttgat ttgcttctga cagtagctta
    17401 ttcaattcag gtcggtttaa cttcgtacca ctatagtttt ccacgtacac aatggtttcg
    17461 cccaaattca agttttggtt tagatcctga agaatctgca aagccctttc tgcatcttga
    17521 tctttagttg aagctcgtag ataaatacgt gtattcattt ctatcattta gccttaattc
    17581 gattagatca atgataatgc tatcatttaa tttttgcatt aagtttaatg atagatgctt
    17641 tatgttattt ggctcgctat cattcagcta tactattttg ataaaaaagc aggactgaaa
    17701 gccatgctct gggaatttgt ataacgtgta ttatgttaat tttagaaaaa acttaaaatt
    17761 atctattaaa gaatcatata tttttggatt acttataagt gaaatagcac ctatatagtg
    17821 caggcttagc tagaaaaact ataacactct aagaaagtat gggtttttat gtacaaggca
    17881 atttcataag aagccagatg ataaaattcg aggctcccca attttgtaaa tcaaatatat
    17941 gcaaaataat gtgagtaagc cggcagtacc agcattaaca ctggctgcac taggagtagt
    18001 attcggcgat ataggaacga gtccattata tgcattaaaa gaaagctttc atgcgacacg
    18061 cgggctacct attaatgaac ttaatatcct gggaattctc tctttaatct tttggaccat
    18121 taccttaatt gtttcgctta aatatgtttt ggtgatcatg agagctgata acaatggtga
    18181 agggggtatc atggcattac tcgccttaaa ccttaggcaa aaaggattgt cccgtggaaa
    18241 aagactggca atcattatct taggtttcat tggagcatcc ttattcttcg gtgac
//
