LOCUS       NZ_CP025337            10047 bp    DNA     circular CON 19-MAR-2024
DEFINITION  Salmonella enterica subsp. enterica serovar Typhimurium strain BL10
            plasmid p10k, complete sequence.
ACCESSION   NZ_CP025337
VERSION     NZ_CP025337.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN07945789
            Assembly: GCF_002762135.3
KEYWORDS    RefSeq.
SOURCE      Salmonella enterica subsp. enterica serovar Typhimurium (Salmonella
            typhimurium)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhimurium
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 10047)
  AUTHORS   Hong,Y.P., Wang,Y.W., Huang,I.H., Liao,Y.C., Kuo,H.C., Liu,Y.Y.,
            Tu,Y.H., Chen,B.H., Liao,Y.S. and Chiou,C.S.
  TITLE     Genetic Relationships among Multidrug-Resistant Salmonella enterica
            Serovar Typhimurium Strains from Humans and Animals
  JOURNAL   Antimicrob Agents Chemother 62 (5), e00213-18 (2018)
   PUBMED   29581119
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10047)
  AUTHORS   Hong,Y.P., Chiou,C.S. and Wang,Y.W.
  TITLE     Salmonella enterica subsp. enterica serovar Typhimurium strain BL10
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 10047)
  AUTHORS   Hong,Y.P., Chiou,C.S. and Wang,Y.W.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-JUL-2018) Center for Diagnostics and Vaccine
            Development, Centers for Disease Control, R.O.C (Taiwan), No.20,
            Wenxin S. 3rd Rd., Nantun Dist., Taichung 408, Taiwan
  REMARK    Sequence update by submitter
REFERENCE   4  (bases 1 to 10047)
  AUTHORS   Hong,Y.P., Chiou,C.S. and Wang,Y.W.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-DEC-2017) Center for Diagnostics and Vaccine
            Development, Centers for Disease Control, R.O.C (Taiwan), No.20,
            Wenxin S. 3rd Rd., Nantun Dist., Taichung 408, Taiwan
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 01-JUL-2017
            Assembly Method                   :: CLC NGS Cell v. 10.1.1
            Genome Representation             :: Partial
            Expected Final Version            :: No
            Genome Coverage                   :: 100x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002762135.3-RS_2024_03_19
            Annotation Date                   :: 03/19/2024 06:42:09
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,079
            CDSs (total)                      :: 4,957
            Genes (coding)                    :: 4,827
            CDSs (with protein)               :: 4,827
            Genes (RNA)                       :: 122
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 85
            ncRNAs                            :: 15
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 38 of 130
            Pseudo Genes (incomplete)         :: 96 of 130
            Pseudo Genes (internal stop)      :: 27 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            Pseudo Genes (short protein)      :: 1 of 130
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP025337.1.
            Bacteria available from necropsy of sick pigs.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..10047
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhimurium"
                     /mol_type="genomic DNA"
                     /strain="BL10"
                     /serovar="Typhimurium"
                     /isolation_source="sick pig"
                     /host="Sus scrofa domesticus"
                     /sub_species="enterica"
                     /db_xref="taxon:90371"
                     /plasmid="p10k"
                     /geo_loc_name="Taiwan"
                     /lat_lon="23.29 N 120.27 E"
                     /collection_date="2011"
                     /collected_by="Hung-Chih Kuo"
     gene            join(9513..10047,1..>71)
                     /locus_tag="CTI29_RS24810"
                     /old_locus_tag="CTI29_25040"
                     /pseudo=""
     CDS             join(9513..10047,1..>71)
                     /locus_tag="CTI29_RS24810"
                     /old_locus_tag="CTI29_25040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001493761.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="ISKra4-like element ISKpn19 family transposase"
                     /name="ISKra4-like element ISKpn19 family transposase"
     gene            complement(join(10046..10047,1..1375))
                     /locus_tag="CTI29_RS24815"
                     /old_locus_tag="CTI29_25045"
     CDS             complement(join(10046..10047,1..1375))
                     /locus_tag="CTI29_RS24815"
                     /old_locus_tag="CTI29_25045"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017900944.1"
                     /GO_function="GO:0009975 - cyclase activity [Evidence IEA]"
                     /GO_process="GO:0009966 - regulation of signal transduction
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="WP_080196049.1"
                     /translation="MVNVEFFNYIECIFMRIKKPHLRPIVITLSVGGILLTSIFLIVVI
                     MVFKRENIEKDLLDANSSYAMKMSDVMSNYIEIAQRELAYGAKKIESTNDIDSLKNEAD
                     RLRLQSGMFNSVLVVSDGAVVLATSPESLGLVGVHLNSSASKLAIEAKKPFISAPYKSA
                     SGNLIIFLSHPIYDKNSNYIGYVGGSIYLKEQSLFSDVLSRHFFKSDTEISIVSDDGNV
                     IFNNDNSAVGRPMVMDDNLKSKLTSSERGEGIFFSSGNKYLLGYAHMKNTAWSVLVYSH
                     ADSVTTILITYAKSVLVLLIVIVITFSLFSYFIASRISIPLEKLAISTNAKDIGGSLVD
                     IKGINAWYVEADRLKKALFTHIKIMIERVDSLNEVALKDPLTGVNNRLGFSNKIQNHKQ
                     GSGASVIAIDVDFFKKINDNFGHGVGDEVLVTLAQVINCGFPGLGRFPQSRGQPERKPE
                     "
                     /name="diguanylate cyclase"
     gene            complement(1681..1896)
                     /locus_tag="CTI29_RS26965"
     CDS             complement(1681..1896)
                     /locus_tag="CTI29_RS26965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeD family mobilization/exclusion protein"
                     /protein_id="WP_000137421.1"
                     /translation="MTELEKQLLSALEQLQQDYSKRLDEWENAFAEWRTMSGLMQRENA
                     ALSERVTGLSRQVQSLSEQLRRLSQG"
                     /name="MbeD family mobilization/exclusion protein"
     gene            complement(1900..2385)
                     /locus_tag="CTI29_RS26970"
     CDS             complement(1900..2385)
                     /locus_tag="CTI29_RS26970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012565228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeB family mobilization protein"
                     /protein_id="WP_012482081.1"
                     /translation="MSSLLTLAKDLEQKSKAQQQSTGEMLKAAFSEHEQSVRAELNESE
                     KRISAAILDHDRKLSSAMSQRTKGMVRMVSQTWLTIVLVSVLLIASSAGILWWQSQQIL
                     DNYTTIREQKSTQAMLSERNSGVQLSTCGEQRRSCVRVNPEAGRFGEDSSWMILAGK"
                     /name="MbeB family mobilization protein"
     gene            complement(<2420..3124)
                     /locus_tag="CTI29_RS27615"
                     /pseudo=""
     CDS             complement(<2420..3124)
                     /locus_tag="CTI29_RS27615"
                     /inference="COORDINATES: protein motif:HMM:NF015397.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /name="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            complement(3063..3386)
                     /locus_tag="CTI29_RS24825"
                     /old_locus_tag="CTI29_25055"
     CDS             complement(3063..3386)
                     /locus_tag="CTI29_RS24825"
                     /old_locus_tag="CTI29_25055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000957083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="WP_015059464.1"
                     /translation="MLTIWVTEDEHRRLLDRCDGKQLAAWMRQTCLDEKPARAAKLPSI
                     SPALLRQLAGMGNNLNQIARQVNAGGGTGHDRVQIVAALMAIDAGLERLRHAVLEKGAD
                     DDR"
                     /name="MobC family plasmid mobilization relaxosome protein"
     gene            4036..4194
                     /locus_tag="CTI29_RS24835"
                     /old_locus_tag="CTI29_25065"
     CDS             4036..4194
                     /locus_tag="CTI29_RS24835"
                     /old_locus_tag="CTI29_25065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001396189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001658417.1"
                     /translation="MHEPPVQSDCCASSGNFQLDSNPERHDKAPLAAAIGNWELVDLDI
                     ESLEVVA"
                     /name="hypothetical protein"
     gene            complement(4437..4742)
                     /locus_tag="CTI29_RS27110"
     CDS             complement(4437..4742)
                     /locus_tag="CTI29_RS27110"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: protein motif:HMM:TIGR00254.1"
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA];
                     GO:0046872 - metal ion binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="WP_223229636.1"
                     /translation="MPKPDNSCCRSEDIVCRFGGEEFVVFLPNTSVVTAECVAERIRSV
                     IESTVFPNNLRVTVSAGVATQEDPLGGIDFLLKNADDALYQAKGEGRNKVIVYSAI"
                     /name="GGDEF domain-containing protein"
     gene            complement(<4728..5758)
                     /locus_tag="CTI29_RS24840"
                     /old_locus_tag="CTI29_25070"
                     /pseudo=""
     CDS             complement(<4728..5758)
                     /locus_tag="CTI29_RS24840"
                     /old_locus_tag="CTI29_25070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612174.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /name="IS3 family transposase"
     gene            6153..6809
                     /locus_tag="CTI29_RS24845"
                     /old_locus_tag="CTI29_25075"
     CDS             6153..6809
                     /locus_tag="CTI29_RS24845"
                     /old_locus_tag="CTI29_25075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001516695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinolone resistance pentapeptide repeat protein
                     QnrS1"
                     /protein_id="WP_001516695.1"
                     /translation="METYNHTYRHHNFSHKDLSDLTFTACTFIRSDFRRANLRDTTFVN
                     CKFIEQGDIEGCHFDVADLRDASFQQCQLAMANFSNANCYGIEFRACDLKGANFSRTNF
                     AHQVSNRMYFCSAFISGCNLSYANMERVCLEKCELFENRWIGTNLAGASLKESDLSRGV
                     FSEDVWGQFSLQGANLCHAELDGLDPRKVDTSGIKIAAWQQELILEALGIVVYPD"
                     /name="quinolone resistance pentapeptide repeat protein
                     QnrS1"
     gene            complement(7128..7742)
                     /locus_tag="CTI29_RS24850"
                     /old_locus_tag="CTI29_25080"
     CDS             complement(7128..7742)
                     /locus_tag="CTI29_RS24850"
                     /old_locus_tag="CTI29_25080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017412822.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_014839983.1"
                     /translation="MFIGYIRMSKADGSQTNDLQRDALIAAGVDAAHFYEDRASGKREE
                     RPGLTACLKALRPGDTLVVWKLDRLGRDLRHLINTVHDLTARGTGLKVLTGHGATIDTT
                     TAAGKLVFGIFAALAEFERELIAERTTAGLASARARGRNGGRPYKMTPVKLRLAMASMG
                     QSETKVSTLCQELGITRQTLYRHISPVGQLRADGIKLFNRG"
                     /name="recombinase family protein"
     gene            7904..>8086
                     /locus_tag="CTI29_RS24855"
                     /old_locus_tag="CTI29_25085"
                     /pseudo=""
     CDS             7904..>8086
                     /locus_tag="CTI29_RS24855"
                     /old_locus_tag="CTI29_25085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015060658.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4158 domain-containing protein"
                     /name="DUF4158 domain-containing protein"
     gene            8222..8767
                     /locus_tag="CTI29_RS24860"
                     /old_locus_tag="CTI29_25090"
     CDS             8222..8767
                     /locus_tag="CTI29_RS24860"
                     /old_locus_tag="CTI29_25090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001493763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid pRiA4b ORF-3 family protein"
                     /protein_id="WP_001493763.1"
                     /translation="MVWRRLRIAADTSLAALHFIFQIVQGWGDDHLHQFHIYGKDYGIS
                     YEGGIGFVDNPFRVVIDDFAFDAGDRFTYEYNFFEHWLHDIRVEAIYENSTLKAPFCIS
                     GHGMPGATAADEFDKTLAFLEAIVNADDETTVGEIRPFADDLDAVRFNRHKINRQLSRL
                     DLASPVLEPEVIWLGRRR"
                     /name="plasmid pRiA4b ORF-3 family protein"
     gene            8904..9476
                     /locus_tag="CTI29_RS24865"
                     /old_locus_tag="CTI29_25095"
     CDS             8904..9476
                     /locus_tag="CTI29_RS24865"
                     /old_locus_tag="CTI29_25095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001493762.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001493762.1"
                     /translation="MQYAYIRVSSADQNTARQEEALSKAGFQPDKICVEHASAKDTNRP
                     GLQELLGQLRPGDTLLVHSIDRLCRNMSDMCAVTTRLRDQGVTLIFLKEQLTFSAGTNN
                     PMQELQLHMMSAFSQFERALLKERQADGIAAKKARGEKTGRPGADIKKIQEIDALRSRG
                     VRLRIACDHAGLGVSTYYKLRHQMNNQ"
                     /name="recombinase family protein"
     ARG             6154..6806
                     /name="qnrS1"
                     /gene="qnrS1"
                     /gene_name="quinolone resistance pentapeptide repeat
                     protein QnrS1"
                     /tool="amrfinderplus"
                     /drug_class="QUINOLONE"
                     /identity="100.0"
                     /coverage="100.0"
     Typing          3657..4203
                     /name="rep_cluster_2335"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="91.652"
                     /coverage="90.0"
                     /evalue="0.0"
     Typing          complement(1578..3073)
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="91.583"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 attcaggttt tctttccggc tgcccccgcg actgggggaa cctgcccagg ccaggaaaac
       61 cgcaattaat aacctgagcc aaagtaacaa gaacctcatc tccgacccca tgcccgaagt
      121 tatcatttat ttttttaaaa aaatcaacat caatagcaat aactgaagcc cctgaaccct
      181 gcttgtgatt ttgtatttta tttgaaaacc ccagtctgtt gttcacgccg gttaggggat
      241 ctttaagcgc cacctcattt agagaatcaa ctctttctat cattatctta atatgcgtaa
      301 aaagtgcctt ttttagtcgg tcggcttcga cataccaagc attgatacct ttaatatcaa
      361 ctagcgaacc ccctatatct ttagcattgg tagatatagc aagcttttct aaaggaattg
      421 aaatacggga agcaatgaaa tatgaaaaaa gtgaaaatgt aataactatt acaattagca
      481 gaacaagtac actcttagca taagtaataa gaatagtagt cacgctgtca gcgtgactat
      541 aaaccaacac actccaagca gtatttttca tatgagcata accaagaaga tatttattcc
      601 ccgaagaaaa aaagataccc tcacctctct cagacgaagt taacttcgat ttcaaattat
      661 catccataac cattggtcga ccaacagcac tgttatcgtt attaaagatc acatttccat
      721 catcactaac aatgctaatt tcagtgtcgc ttttgaaaaa atgcctgctc aaaacgtcgc
      781 taaataaact ctgttccttt agatatatag acccgccgac ataccctata taattactat
      841 tcttatcata aataggatgt gacaaaaaaa taatcaaatt cccagaagct gatttgtaag
      901 gtgccgatat aaatggtttt ttagcctcaa tcgccaactt actggcactt gaattcaagt
      961 gaactccaac taaaccaagt gattctggcg aagtcgccag aacaacagca ccatcactaa
     1021 caacaagaac tgaattaaac ataccagact gcaatcttaa cctatccgcc tcatttttaa
     1081 gtgagtcaat atcattagtt gactctattt tttttgcgcc atacgccaat tcacgttgag
     1141 caatttcaat ataattactc attacatctg acattttcat agcgtacgat gaattagcat
     1201 caagcaagtc tttttctata ttttcgcgtt taaaaaccat aataacgaca atcagaaaaa
     1261 tagaagtcaa caaaatacca ccaacggaca aggttatgac tatcggacga aggtgaggct
     1321 ttttaattct cataaaaata cactctatat aattaaaaaa ttccacattt accataacat
     1381 cccttgcccg caccgccccg gacgggttcg gcgcgaatgc ggcgtcagcc cggtaaaacc
     1441 ggcagtaaac tccccgctaa accgcgcttt ttgagccaga taaatttccc caagatgcat
     1501 agccatgcag ccggggggat ggcaccgcct ttcggcgggg atctgcgccg aaagacccgt
     1561 tttatccggt ttgttacagc gacggaccgt tgtacgtccg ctggcgctgc gatcgttcca
     1621 gctccagcgc tttccggtgc tgcgccgccc gttcctgctc ccggtgcgcc tcgataccat
     1681 tcagccttgc gacaaccggc gcagctgctc gctcaaactc tgcacctgcc tgctcaagcc
     1741 cgtgacgcgc tcgctcagcg ccgcgttctc ccgttgcata agaccagaca tcgtccgcca
     1801 ttccgcgaag gcgttctccc actcgtccag ccttttcgag tagtcctgct gtagctgctc
     1861 taatgcgctc agcaactgtt tttccagctc cgtcatgtgc tatttccccg ccagtatcat
     1921 ccagctcgaa tcctctccga accgtcccgc ttccgggttc accctcacgc agctgcgtct
     1981 ctgctcgccg caggtcgaga gctgcacgcc gctgttccgc tcggacagca tcgcctgcgt
     2041 gctcttctgc tcccggatgg tcgtgtaatt gtcgagtatc tgctgactct gccaccacag
     2101 aatgcccgcg ctcgatgcga tcagcaggac ggaaaccagg acgatggtca gccacgtctg
     2161 gctgaccata cgcaccatgc ctttcgtgcg ctggctcatg gctgaggaca gcttccggtc
     2221 gtggtcgagg atggcggcgc tgattctctt ctcgctttcg ttcagttccg ctctgacaga
     2281 ctgctcgtgc tcgctgaatg cggctttcag catctcgccg gtactctgct gctgcgcttt
     2341 cgatttctgc tctaagtcct tcgccagcgt taaaagactg ctcatagatg gctcccttta
     2401 gtcggatgtt tcgccccccg tccgggtcgg caatgctgat actgcttttc gtggtgcgta
     2461 ccacctcaaa acccgcgttt tccagcgcct cagtaacgtc ctgacgggtt ttcagctccc
     2521 cggacgaggc taaggccagc aaaccccggg tgatcgcctg agctgcctcc tgcttcgttt
     2581 ccggcagcgc ggacggcgtg accagcgccc gccggttttc cggcgcattc gggtcgtgca
     2641 gccccagcct gccgttcacg atggtctgcc aggcatcgat gcgcggacgg tcagcgcggt
     2701 cgtaatacgg ctggagcctt ttgccggtca gcagctccgt gttcgggatc aggaagttca
     2761 gctccagccg ccccttgtcc tggtgctcca cccacagcac gctgtactgg tctttatcga
     2821 gtccgggcat cagaacacgc tcgaagctcg ccatcagttt ttcacgctga ccgggcggta
     2881 agtcctgttc ggcaaacgac agcaccccgg aggtgtactt tttggcgtag ggcgaggcgt
     2941 cgattagctc ccggacttcc tccggtttac cctgcagaac gctggcgccg tcgcgcttgc
     3001 ggtcattacc cagcagataa tccaccggac cggcaccgcc gccgcgccct cgtgggtgaa
     3061 atttaacgat catcgtcagc ccccttttcc agcacagcgt gccgcaggcg ctcaagtccg
     3121 gcatcaatgg ccatcagcgc agcgacaatc tgtacgcgat catgtccggt accaccaccg
     3181 gcgttaacct gccgggcaat ctgattgagg ttgtttccca taccggcaag ttgacgaagc
     3241 aacgccggcg agatcgacgg aagtttggcg gcacgagcag gtttctcgtc gagacacgtc
     3301 tgccgcatcc aggccgcgag ctgcttaccg tcgcagcgat ccagcagacg ccggtgctcg
     3361 tcttcagtta cccatatcgt gagcattttg ctgcgtttgt ctgccaatcc ggcctcctga
     3421 taacgccggg acggacgggg aattatttcc cggtcggcgc ggtgttggac aagccgcagg
     3481 cgcgtcagtg ccttttagcg ggtttcgggg cgcagccctg aaccagtcac gtagcgctag
     3541 cggagtgtat actggcttaa aatgtaacat cgcagaaaca tcaagcatag ctgccacata
     3601 aagcaggtga aaaatgagat tcgtatgcgt cagcagaaga tgcactgccg gagaaatgcc
     3661 gcttcctcgc tcactgactc gctccgctcg gtcgttcggc tgcggcgagc ggtaccggct
     3721 tacgggcggg gcggaaattt cctggaagat gctaggaaga aacttaacag ggaagcgata
     3781 aggccacggc agagccgttt ttccataggc tccgcccccc tgacaagcat cacagaatct
     3841 gacgctcaaa tcagtggtgg cgaaacccga caggactata aagatcccag gcgtttcccc
     3901 ctggtagctc cctcgtgcgc tctcctgttc ctgcctttcg gtttaccggt gtcattccgc
     3961 tgttatggcc gcgtttgtct cattccacgc ctgacactca gttccgggta ggcagttcgc
     4021 tccaagctgg actgtatgca cgaacccccc gttcagtccg actgctgcgc ctcctccggt
     4081 aactttcaac ttgattccaa cccggaaagg cacgacaaag cgccactggc agcagccatt
     4141 ggtaactggg aattagtgga tttagatatc gagagtcttg aagtggtggc ctgactacgg
     4201 ctacactgaa aggacagtat ttggtatctg cgctccacta aagccagtta ccttcggaag
     4261 aaagtgttgg tagctcttaa ttccggcaaa cgaaccaccg ttggtagcgg tggttttttt
     4321 gtttacaggg catgagctta cgacgacatc gaagggataa caagaggatc cgcttcttga
     4381 acccttttcc ccacaaaaaa acgccacact agcgcgtaaa gcgtcatcaa aaaaactcaa
     4441 atagcgctat atacaatcac tttattacgc ccctctccct tggcttgata aagagcatca
     4501 tcagcatttt tcagcaaaaa atcgatccca ccaagaggat cctcttgtgt tgccacacca
     4561 gcagagacgg tgacccgcaa gttattaggg aaaacagtac tttcaataac actcctaata
     4621 cgctccgcaa cacactccgc tgttaccaca gatgtattcg gcagaaaaac aacaaactct
     4681 tctccaccaa accgacaaac aatatcttca ctacggcagc aagaattatc cggtttcggc
     4741 atgatgctga tgtagtcccg ttttatcgtc atcacgaagc tttctgctat gccattgctt
     4801 tccgggcttc gcactgctgt cgtacaaggc tccagtccca gcaaccgggc gaacgccggc
     4861 actgttggca actgccttcc gaagcgtttt tccaccgcac ccagcatgac atcctgcacc
     4921 gtttctttgt catagcctcc ggtgctcgct gcccaatcaa tgatctccct gtcgcagcag
     4981 tcctgcgcga aggtcacccg cagcttttcg ccattatcac agcggaactc aaagccatct
     5041 gagcaccagc gccggttact ttccgctact gctacgcgcc ccttatgggc ccgcttacgg
     5101 caaggatcag cgggtttacg ttcaagaagc agattatgcg ttctcataat gcgatacacc
     5161 cgctttgcat taaccacagg caggccgtcc cgctccgact cccgtcgcag cagcgcccac
     5221 acacggcgat aaccatacgt cggcaggtca gccaccgcca tgtttatccg ggacaatacg
     5281 gtggtatcgt cagaacgggg ctgccgtctg cgatcctgtc agtcagatgg ccggtgaacc
     5341 cgaatgctca actgcgcacg cgacacgcca agacttctgc aaacgtcgct tattcgtcgt
     5401 tcccaggcaa cgagggcgca tgcgcaatcc atttttttgc ccggccgaac tccacggcct
     5461 ctttgagtat ctcggcttcc atcgtctttt tgcccagaag gcgctggagt tcgcgaattt
     5521 gcttattggc ggcagcgagt tcggaggccg gcaccacttc ctcgcccgat gcaacagccg
     5581 tcagtgaacc gtcttaatat tgcttgcgcc atttgaatat ctggtttgca ttgatgccat
     5641 gcaggcgcgc gacatgagac acggtcatac cgggctccat agtctgctga ataatggcaa
     5701 ttttttcctg cggtgtacga cgccgacgcc gctcaggtcc tgataacact tcaaccatct
     5761 tatcgttctg actggtatta aacatagttc caagactacc tcttatttta agagagtcga
     5821 agtgtctggt gatctatggg gccagtctag ccctcttcca agtgtaggga gatatagtca
     5881 aagtttgctt ctccgccgat gagtccgccc tgcgtcggat agtccgattt tttaccggcg
     5941 aagcacggct ctcctaaccc tatctaaagc gaataacttt tttcaacagg gccgcgtgcc
     6001 aatgcaagag cgataggcgc tctacgcgcc aatttgacca cttaaaacag gtaaattgag
     6061 gggttgtaat gtgttgatgt aacaggcttt tattttaatg tcttggcata tgtataatgg
     6121 tagtctagcc ctcctttcaa caaggagtac tcatggaaac ctacaatcat acatatcggc
     6181 accacaactt ttcacataaa gacttaagtg atctcacctt caccgcttgc acattcattc
     6241 gcagcgactt tcgacgtgct aacttgcgtg atacgacatt cgtcaactgc aagttcattg
     6301 aacagggtga tatcgaaggc tgccactttg atgtcgcaga tcttcgtgat gcaagtttcc
     6361 aacaatgcca acttgcgatg gcaaacttca gtaatgccaa ttgctacggt atagagttcc
     6421 gtgcgtgtga tttaaaaggt gccaactttt cccgaacaaa ctttgcccat caagtgagta
     6481 atcgtatgta cttttgctca gcatttattt ctggatgtaa tctttcctat gccaatatgg
     6541 agagggtttg tttagaaaaa tgtgagttgt ttgaaaatcg ctggatagga acgaacctag
     6601 cgggtgcatc actgaaagag tcagacttaa gtcgaggtgt tttttccgaa gatgtctggg
     6661 ggcaatttag cctacagggt gccaatttat gccacgccga actcgacggt ttagatcccc
     6721 gcaaagtcga tacatcaggt atcaaaattg cagcctggca gcaagaactg attctcgaag
     6781 cactgggtat tgttgtttat cctgactaat tgctttgatg tgtgatttta aacgctcaaa
     6841 tttataaaac gaataatatt gtcaaccttg caataataga catagggaca accatgtata
     6901 aatttttacc ctcaggcgtc ttcacaatag agccatatag cagtgggtca cttagtgggc
     6961 ttaatttttc cattaaagat aatattaata ttgctcagta taaaacatca tatggtagcc
     7021 catcttggca agtaaacata aggctgccat ttataaggca ctgttgcaaa aatgtggagg
     7081 tgataggggt actacgccgg aaccccagat ttttccgtcc gttcaaatta tccacggttg
     7141 aacagcttga tcccgtccgc ccgcagttga ccaacagggg aaatatgcct gtacaaagtt
     7201 tgccgggtta tcccaagttc ctggcatagc gtactgacct ttgtttctga ttgtcccatt
     7261 gatgccattg ccagtcgcag tttgactggc gtcattttat aaggtcggcc gccgttccgc
     7321 ccacgggctc ttgctgatgc cagacctgca gtcgttcttt cagcaatcag ttcgcgctca
     7381 aactccgcca gtgcggcaaa gataccgaag acaagcttgc cagcggccgt tgttgtgtcg
     7441 atagtcgccc cgtgaccggt cagcactttc agaccggtcc ccctcgcggt caggtcgtgc
     7501 actgtattaa tgagatgacg aagatcacga ccgaggcggt ccagcttcca tacgaccagc
     7561 gtgtctccgg gtcgtagtgc tttcagacag gctgtaagtc caggacgctc ttctcgtttg
     7621 cccgatgccc ggtcctcata aaaatgtgcg gcatcaacac ctgcggcgat cagtgcatca
     7681 cgttgtaaat cattcgtctg cgaaccatca gcttttgaca tccgaatata tccgatgaac
     7741 atatttcctc tgtcacatat acgttcgatt atgtgacatt ctgatttggg taccataatc
     7801 tgtcaacggt agtcacatta cccgtaattt aaattatgac acgtaaaggt tctatgttaa
     7861 tgataatgtg acaagcgcgt ttaaataggc ataaggatca gagatgccta ctaaaaataa
     7921 gctcctcagt attctttcgg acgccgagca ggaagcgctc tatggtctac ctgatttcga
     7981 tgatgcacag cggctggagt ttctggcgct gaatggatat gaactggcgc tggcctgcag
     8041 tcgccggggg cttcacgctc aaatttattg catcatccag atcggagagc atgaaaaacc
     8101 tcggggcagc catcgaatga tgccatctac aggggttaaa ataaccacca tcatttcata
     8161 acaatacctg ctgactatga agatctacgt catcaaaata gcagttcatg gagtcagtcc
     8221 gatggtctgg cgtcggctga gaattgctgc cgacacgtca ctggccgcgc ttcacttcat
     8281 tttccagata gtgcagggct ggggggacga ccatctccat caatttcaca tttatggcaa
     8341 agattacggt atctcctacg aaggaggcat cggttttgtc gataatccgt tccgggtcgt
     8401 gattgatgat tttgcttttg atgctggcga tcgctttacc tatgaataca atttctttga
     8461 gcactggctt catgacattc gtgttgaggc catttatgaa aactctacgc tgaaagcgcc
     8521 gttttgtata agcggccatg gtatgcccgg agccacagct gcggatgagt tcgataaaac
     8581 cctggcgttt cttgaagcta tcgttaatgc ggatgatgaa acaacggtcg gcgagatccg
     8641 cccttttgct gacgacctgg atgctgtcag gttcaaccgc cacaaaatca accggcaact
     8701 gagcaggctc gaccttgcat ctccggtact ggagcctgaa gttatctggc tgggccgtcg
     8761 tcgctgactg atgtctataa aggtatacgt tttcagcatg cctctcagat ccccgaaaaa
     8821 atgtctataa acctccctaa atcagtgttt atggattatt ctttaaatct ctatgatgtt
     8881 taaagacctt ccggaggttt tgcgtgcaat atgcctacat cagggtaagc tcggccgatc
     8941 agaatacggc ccgtcaggaa gaggcattgt caaaggcggg ttttcagcct gataaaattt
     9001 gtgttgagca tgccagcgcg aaggacacaa accgcccggg gttacaggaa ctcctggggc
     9061 aattacgccc tggtgatacg cttctggttc attccatcga tcgcctttgc cggaatatgt
     9121 cggatatgtg cgctgtcacc acccggcttc gtgaccaggg cgttaccctt atttttctga
     9181 aagagcagct gacgttcagc gccggcacaa acaatccgat gcaggaactg cagctgcaca
     9241 tgatgtcggc attcagccag tttgaacgag ccttactgaa ggaaaggcag gccgacggca
     9301 tcgccgcgaa aaaagcacgg ggtgaaaaaa cagggcgccc cggcgccgat atcaaaaaga
     9361 tccaggaaat tgacgcactc agaagcagag gggtcaggct caggatcgcc tgcgaccatg
     9421 cgggccttgg cgtttccaca tattataagc ttcgtcacca gatgaacaac cagtagccgg
     9481 gagatagtca tccaccacag caggaggcaa tgatgcaact gacgctccag atagtcatca
     9541 ccgatgaatc aggctccagt cgaacggagg aactgatgac aatccagaaa tcaggggaga
     9601 cccggaacga catcggatta tcggtgtcag aatccaagct gttgctgaat acggtccagc
     9661 agtcggtggt ccagctgcag gcagacgaat atactcaaca ccatatccgg tgccctcact
     9721 gccttgctgc gcgcagaatc aaaggcaaac agaaaatacg gtaccggacg ctgtttggcg
     9781 ttattccggt atccgggctt cgggtgtacc ggtgccgttg tgaagagagt gatacaaaga
     9841 cagtcagttt gctcagcgac tgggccggcg attattctca cccggcactg aaatatattg
     9901 aaacccgctg ggcctcgatg atctcctatg aaatgacgac tcgtctgctg aaagatattc
     9961 tgccggtggg ccacagcctg aatgcctcaa cggtgaggaa tcatttatgc caggtggcgc
    10021 agcgtcttga cgctgaggct gaagctc
//
