LOCUS       NZ_CP024999            20730 bp    DNA     circular CON 19-FEB-2024
DEFINITION  Staphylococcus aureus strain 55-99-44 plasmid punamed1, complete
            sequence.
ACCESSION   NZ_CP024999
VERSION     NZ_CP024999.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN08024196
            Assembly: GCF_002803885.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 20730)
  AUTHORS   Baig,S., Johannesen,T.B., Overballe-Petersen,S., Larsen,J.,
            Stegger,M. and Larsen,A.R.
  TITLE     Novel SCCmec Type XIII (9A) Identified in an ST152 MRSA
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 20730)
  AUTHORS   Baig,S., Stegger,M. and Larsen,A.R.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-NOV-2017) Bacteria, Parasites, and Fungi, Statens
            Serum Institut, Artillerivej 5, Copenhagen 2300, Denmark
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 22-DEC-2016
            Assembly Method                   :: SPAdes v. 2016-12-22
            Assembly Name :: Staphylococcus aureus strain 55-99-44 complete
            genome
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 107.798x
            Sequencing Technology             :: Oxford nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/19/2024 01:08:07
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,731
            CDSs (total)                      :: 2,653
            Genes (coding)                    :: 2,579
            CDSs (with protein)               :: 2,579
            Genes (RNA)                       :: 78
            rRNAs                             :: 6, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 41 of 74
            Pseudo Genes (incomplete)         :: 27 of 74
            Pseudo Genes (internal stop)      :: 24 of 74
            Pseudo Genes (multiple problems)  :: 15 of 74
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP024999.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..20730
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="55-99-44"
                     /isolation_source="Infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="punamed1"
                     /geo_loc_name="Denmark"
                     /lat_lon="55.66 N 12.58 E"
                     /collection_date="2015-06-08"
                     /collected_by="Anders Rhod Larsen"
                     /genotype="ST152"
     gene            join(20537..20730,1..1250)
                     /locus_tag="CU118_RS14065"
                     /old_locus_tag="CU118_14065"
                     /pseudo=""
     CDS             join(20537..20730,1..1250)
                     /locus_tag="CU118_RS14065"
                     /old_locus_tag="CU118_14065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790716.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Mu transposase C-terminal domain-containing
                     protein"
                     /name="Mu transposase C-terminal domain-containing protein"
     gene            1243..2058
                     /locus_tag="CU118_RS14070"
                     /old_locus_tag="CU118_14070"
     CDS             1243..2058
                     /locus_tag="CU118_RS14070"
                     /old_locus_tag="CU118_14070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019467708.1"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_000164958.1"
                     /translation="MTKNQNFIETKEYKRFAEFCDACIKYQYIGICYGQPGVGKTLSSR
                     YYTNWDTIEKQVNHRGWEDLASKTTDDILSVDKIFYNAPAEKQTKLRNDLYSITAIIDL
                     GQKLHVVNKYGHEHSKHYSDMFKYIDLIIVDEIDRLKVQHLEQLRAIYDEHNLAMIFIG
                     MPGIEKKLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWQDLGFDLKLEDFTDYEAIT
                     TIIKITKGNFRLIHRLFAQIDRIMDINGLDKISTEVVETARDSLVIGIR"
                     /name="AAA family ATPase"
     gene            complement(2178..3152)
                     /locus_tag="CU118_RS14075"
                     /old_locus_tag="CU118_14075"
     CDS             complement(2178..3152)
                     /locus_tag="CU118_RS14075"
                     /old_locus_tag="CU118_14075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="WP_000072391.1"
                     /translation="MSNTKIKYQIFISSTYLDLIEERQAVVEAVLNSNNIPAGMELFNS
                     SSKSQWEIITQWINESDAVILLLGSSYGTIDSEENISYTEMEYNFAKSLGKPIYVFEMN
                     KASTESAEKSKKLDEFKTKVKENRLISPNINDISELKSKVSQTLMQSVPSEIKENSGWI
                     RVQDCGKNVKKLKKLDAIQRDLDTYDFLKEELYKIFMYVKTFYFQHTPFDDSYIEDIEN
                     YLLNYENNPHKSFMKIKVYDYKNFLKHLKNILILIKQGKKPLAQAGHFKLSFYEEDLKL
                     LQKNYKTTLVDIKGLNKHFYKECDRCLKAYNIFIEGINKHLYE"
                     /name="DUF4062 domain-containing protein"
     gene            complement(3364..3456)
                     /locus_tag="CU118_RS14215"
     CDS             complement(3364..3456)
                     /locus_tag="CU118_RS14215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(3625..3972)
                     /locus_tag="CU118_RS14080"
                     /old_locus_tag="CU118_14080"
     CDS             complement(3625..3972)
                     /locus_tag="CU118_RS14080"
                     /old_locus_tag="CU118_14080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119691.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNQEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            complement(3991..4608)
                     /gene="cadD"
                     /locus_tag="CU118_RS14085"
                     /old_locus_tag="CU118_14085"
     ARG             complement(3995..4608)
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="99.51"
                     /coverage="100.0"
     gene            complement(5819..>6101)
                     /locus_tag="CU118_RS14395"
                     /old_locus_tag="CU118_14090"
                     /pseudo=""
     CDS             complement(5819..>6101)
                     /locus_tag="CU118_RS14395"
                     /old_locus_tag="CU118_14090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199895.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            complement(6112..6788)
                     /locus_tag="CU118_RS14305"
                     /pseudo=""
     CDS             complement(6112..6788)
                     /locus_tag="CU118_RS14305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /name="replication initiator protein A"
     gene            7199..7942
                     /locus_tag="CU118_RS14105"
                     /old_locus_tag="CU118_14105"
     CDS             7199..7942
                     /locus_tag="CU118_RS14105"
                     /old_locus_tag="CU118_14105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843758.1"
                     /translation="MKSVKRLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESATEDKQKKESDNINFESKSDAQIVEILKNQINTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNAR
                     QNVDAQEKTYTTSPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAQREDVSANPND
                     NDSDIEEKSEETEPKKGFWSRLFGN"
                     /name="DUF536 domain-containing protein"
     gene            complement(8161..8346)
                     /locus_tag="CU118_RS14110"
                     /old_locus_tag="CU118_14110"
     CDS             complement(8161..8346)
                     /locus_tag="CU118_RS14110"
                     /old_locus_tag="CU118_14110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000466619.1"
                     /translation="MFGDQRQEATKYVIKEGYQDIYFLNKNGEWYYFEVRSVWRGKHII
                     RVKDGLLGWRKEIVTE"
                     /name="hypothetical protein"
     gene            8495..8566
                     /locus_tag="CU118_RS14220"
     CDS             8495..8566
                     /locus_tag="CU118_RS14220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_106873653.1"
                     /translation="MNEILVHIMTTAISGCLVTLFGY"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(8805..9146)
                     /locus_tag="CU118_RS14115"
                     /old_locus_tag="CU118_14115"
     CDS             complement(8805..9146)
                     /locus_tag="CU118_RS14115"
                     /old_locus_tag="CU118_14115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761340.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000761341.1"
                     /translation="MKLAEAIKEQRELKGWSQEELANILKVSRQSVSKWESAKNYPSLD
                     ILIAMSDLFGISLEHLIKGDARFKKVILEGNYRESNRVPSIVDFLYDFWWLFFPVAGFL
                     VWAIHSFMG"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(9233..10093)
                     /locus_tag="CU118_RS14120"
                     /old_locus_tag="CU118_14120"
     CDS             complement(9233..10093)
                     /locus_tag="CU118_RS14120"
                     /old_locus_tag="CU118_14120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000145511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_000145511.1"
                     /translation="MTGETVVYKNEMNLVPLRRFTATEINLFFAMCNKLKEQDTNTLRL
                     SFDELKKLSNYSPETRNINRFANDLDNVYKKMLNLTIRYEDDDVIERFVLFNHYRIHKR
                     EQYLEISTSSNLKHILNSITNNFTKFELKEMTRLKSTYSKNMFRLLKQYKHTGYLKIHI
                     DDFKNRLDIPKSYRMTDINKNVFKPIIIELGSIFNNLTINKIKAKKGRKIEWIEFTFDA
                     EKRIHNKRQPQMSKIDKSRQYVRREKTPKWLEERSYEKQPQKDYDPQLEKEREDFLKQL
                     ELNWE"
                     /name="replication initiation protein"
     gene            complement(10477..11022)
                     /locus_tag="CU118_RS14400"
     CDS             complement(10477..11022)
                     /locus_tag="CU118_RS14400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001805533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000273005.1"
                     /translation="MYEIKTKNVGGWFHKEKQETGNIVITKTDFEKYTKQIKAAQMILD
                     DYECIKSGKSLKKAEKQNESLVNELTSVHMENEKLVEEFNDLAQRYNYLLSENEKKDKE
                     LNYTLKLFNQVFKIIKSMMKEERYHTLINHIDNHLDNSKIREVMTIDNNDEQFFKKKYQ
                     AQEREIIFKEDREDGYTL"
                     /name="hypothetical protein"
     gene            complement(11116..11745)
                     /gene="mobV"
                     /locus_tag="CU118_RS14405"
                     /pseudo=""
     CDS             complement(11116..11745)
                     /gene="mobV"
                     /locus_tag="CU118_RS14405"
                     /inference="COORDINATES: protein motif:HMM:NF013258.4"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /name="mobV"
     gene            complement(11983..12609)
                     /locus_tag="CU118_RS14135"
                     /old_locus_tag="CU118_14135"
     CDS             complement(11983..12609)
                     /locus_tag="CU118_RS14135"
                     /old_locus_tag="CU118_14135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000593103.1"
                     /translation="MIKLENVFVKKGNKNILDGCNFNFEKGKSYALVGESGAGKSTLLN
                     IIAGFEDVSQGSIYIEDKLLKKKVDFYRYTLGYLFQNFALLENQTISQNLDLALKFKKN
                     KKDNMNLKKEVLKKVGLDLDIKRIVSSLSGGEQQRVALARLILKDPKIILADEPTGSLD
                     TKNGKIVIDLLLKLLDENKTMIVVTHDLELAKRFDVIVNISELRS"
                     /name="ABC transporter ATP-binding protein"
     gene            complement(12621..12932)
                     /locus_tag="CU118_RS14140"
                     /old_locus_tag="CU118_14140"
     CDS             complement(12621..12932)
                     /locus_tag="CU118_RS14140"
                     /old_locus_tag="CU118_14140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="WP_000831610.1"
                     /translation="MKRTLIIVTIVLLIIILSLLLVRNEHLDRFNPLLKEKVSYAKVPK
                     DTQDYRNITVYSKNGEKKSYKLDFLGYDPTKEYVKVNHKGKYVRSIEYITKDIPSFLK"
                     /name="YxeA family protein"
     gene            complement(12936..14870)
                     /locus_tag="CU118_RS14145"
                     /old_locus_tag="CU118_14145"
     CDS             complement(12936..14870)
                     /locus_tag="CU118_RS14145"
                     /old_locus_tag="CU118_14145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001670421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="WP_000713729.1"
                     /translation="MKKFKLFLDFSTLLLISGLLFLFFFKENEEIIPESSNILTISNWD
                     KSNSKSKVLDVIESGAKNQNIQIIKSVKDFDNKKEFFVFNSKRNNSDFIRNKTSLLTPS
                     DLLNREIKGKYYIIGEHFNVEELTSELKKAGLTSEVEYINRNILFFELVIDNDLLVPFI
                     FLGVLYLLYFLYDRGYNLKFYAIQKLHGFSTTRIIFHNIHIKIIYWLVLTAIFFIANIL
                     IIHIANLELDFLMFIRRFIVLLFVFACITTLLWLISYSLLLKLSIPLILKGKKGYKFSI
                     FMGTFTKCIMVLILSFLLAQNLNAYTKLKNIYDSEKIWQKLDNYYTLEISPNIRNSEEK
                     QILETNIYNLIKKSEQLGGLLLKNNNIANPDKNNYIPENGNVFFINNNFLNFYKNINHD
                     FKMIDNHSDKINVFIPPRLQYQKSEIQKNHQGWIDFQKQQNKKVDVQVLSKNVSVFSFD
                     RTTNLKFGYLDSPIVMLLTLDDLTGDFYLAAVSQGGYLFKDLDTLKQLLKDNHLEEEIS
                     GITNYKDSVLNELNETKTKMIITIVTIIINVFILLIATVFETIQYFSWNKKQLLLRKIH
                     GYSLFSSNVRYLTISILLSIMLAYTTHILFGSKILLFIIMSIAIIQHLLQIAYIKYLEK
                     YFKDLMREI"
                     /name="bacteriocin-associated integral membrane family
                     protein"
     gene            complement(14945..15238)
                     /locus_tag="CU118_RS14150"
                     /old_locus_tag="CU118_14150"
     CDS             complement(14945..15238)
                     /locus_tag="CU118_RS14150"
                     /old_locus_tag="CU118_14150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="WP_000726502.1"
                     /translation="MKKKFVSSCIASTILFGTLLGVTYKAEAATVHVAGGVWSHGIGKH
                     YVWSYYSHNKRNHGSTAVGKYSSFSGVARPGVQSKASAPKAWGGNKTFYSLH"
                     /name="lactococcin 972 family bacteriocin"
     gene            complement(15652..16260)
                     /locus_tag="CU118_RS14155"
                     /old_locus_tag="CU118_14155"
     CDS             complement(15652..16260)
                     /locus_tag="CU118_RS14155"
                     /old_locus_tag="CU118_14155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002436987.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001566953.1"
                     /translation="MIVGYARVSSNDQNLERQLENLKTFCAEKIFTEKQSGKSIENRPV
                     LQEALNFLRMGDRFVVESIDCLGRNYDEVIHTVNYLKDKEVQLMITSLPMMNEVVGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRI
                     IYHRVVEMLEEGQSISKIAKEVNITRQTIYRIKNDNDLI"
                     /name="recombinase family protein"
     gene            complement(16629..17474)
                     /gene="blaZ"
                     /locus_tag="CU118_RS14165"
                     /old_locus_tag="CU118_14165"
     ARG             complement(16633..17474)
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="99.64"
                     /coverage="100.0"
     gene            17581..19338
                     /gene="blaR1"
                     /locus_tag="CU118_RS14170"
                     /old_locus_tag="CU118_14170"
     ARG             17582..19335
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.56"
                     /coverage="100.0"
     gene            19328..19708
                     /gene="blaI"
                     /locus_tag="CU118_RS14175"
                     /old_locus_tag="CU118_14175"
     ARG             19329..19705
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="99.21"
                     /coverage="100.0"
     gene            19972..20565
                     /locus_tag="CU118_RS14180"
                     /old_locus_tag="CU118_14180"
     CDS             19972..20565
                     /locus_tag="CU118_RS14180"
                     /old_locus_tag="CU118_14180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690636.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690638.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNQKDLNLLKTLYDNGTPI
                     KTIAEQWHVSRTTIYRYLNKLEDKEDEKQGEVSN"
                     /name="recombinase family protein"
     ARG             complement(16630..17474)
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.44"
                     /coverage="100.0"
     BGC             9945..20238
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          complement(5615..5762)
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="81.333"
                     /coverage="100.0"
                     /evalue="2.96e-25"
     Typing          7200..7942
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.866"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(9234..10093)
                     /name="rep_cluster_2214"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(11471..11745)
                     /name="MOBV"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="94.565"
                     /coverage="100.0"
                     /evalue="4.71e-46"
ORIGIN
        1 aatctatgcg acaagagctg ataaaggaac acgtaaaata gaaccaaaga taattgatga
       61 aattgaacgc cttgcgctta tgaataaaag aaatagtata gccacaattc ataggaaaat
      121 cactaattac tgtaaagaaa ataattttga tataccaagt tataaacaaa tttatagtgt
      181 tattaaagcg atgcctaagt ctgttattga tttctctcat cagggtgaaa aatactatca
      241 aaataagtac gatttaatac aaattagaga atcctcgaga cccaatgaaa tatggcaagc
      301 agaccatact ttgctagata tctttatatt agaccaaaaa ggtaatatca atagaccatg
      361 gctaactatt attatggatg actatagtcg tgcaattgca ggctatttct taagttttga
      421 tgccccccaa tgctcaaaac acagcattaa cactacacca agcaatatgg aataaaaatg
      481 ataccaattg gccagtgtgt ggtatacccg aaaaattcta cacagatcat ggaagtgact
      541 ttacttcaca tcatatggaa caagtcgcta ttgatttgaa aattaacttg atgttttcga
      601 aagttggtgt tcctcgtggt cgtggaaaaa tagaacgatt ctttcagaca gttaatcaaa
      661 ctttcttaga acaactgcct ggatatataa acaataatga tactcctagt aatctaataa
      721 attttcacaa ttttgaagaa aaattacgtt actttttaat tgaagattat aatcaaaaag
      781 aacatagtac tattcatacc acgcctatca gtcattggaa tagtaatcac tttttcccta
      841 atatgccaag tagcttagaa caacttgatt tattattgtt ggaaatacct aaatctagaa
      901 aagttcattc agatggcatt cattttcaag gttttcgata cagtaatact aatctagaag
      961 cttatgtagg tgaatatgta ctgattcgtt ataacccaaa tgatatggct gaaatacgtg
     1021 tgttttatag agatgaattt ctttgtactg ctatatgtcc agaaatagct gattactcca
     1081 tagatataaa agacatacag cacgctcgta gtcagagaag aaaacactta aaacaaaata
     1141 ttgctagtcc aagtaccacg gaattaatta aggaagaaaa aaattgtggt tattcacctc
     1201 aagaaacgac taaaaacgtc aaaaaattaa agagatatcg taatgactaa aaatcaaaat
     1261 ttcattgaaa cgaaagagta taaacgcttt gctgaatttt gtgatgcttg tattaaatat
     1321 cagtatattg gtatatgtta tggtcaacct ggtgtcggaa aaactttatc gtctaggtat
     1381 tacacaaatt gggatactat tgaaaaacaa gttaaccata gaggttggga agatttagct
     1441 agtaaaacga ccgatgacat actatcggtg gataaaatat tttataatgc accagcagaa
     1501 aaacaaacta aattaaggaa tgatttatat agtattactg caatcattga tttgggtcaa
     1561 aaattacatg ttgtaaataa gtatggacat gaacatagta aacattatag tgatatgttt
     1621 aaatatattg atttaattat agtagatgag attgatcgcc ttaaagtgca acatttagag
     1681 caattaagag ctatttatga tgaacataat ttagcaatga tatttattgg tatgccgggt
     1741 atagagaaaa aactatctcg ttatcctcaa ctatattcgc gtataggttt tgcgcatgaa
     1801 tttgataatc taagtaaaga tgagacgcat catatattag aatataagtg gcaagactta
     1861 ggatttgatt taaaactcga agactttact gattatgagg caataacgac gattattaaa
     1921 attacaaaag ggaattttag gctgattcat cgtttatttg cgcagataga cagaattatg
     1981 gatataaatg gtttagataa aataagtaca gaagttgtag aaacagctag agatagttta
     2041 gttataggta ttcgataata gaaaaagcaa cgcattttaa tatagtgcgt tgcttttctc
     2101 atttattagg taaagtcatt ctcatatatc gagtaaagtg acaacaatta tatatgtatg
     2161 attagggtgt acttatatca ttcatataaa tgtttattta taccctcaat aaaaatatta
     2221 tatgctttta agcacctatc acattcctta taaaaatgtt tattcaatcc tttaatatcg
     2281 actagcgtag tcttataatt tttttgtaac aattttaaat cctcttcgta aaagcttaat
     2341 ttaaaatgac cggcttgagc taatggcttt tttccttgtt taattaaaat caatatgttt
     2401 tttaaatgtt ttaaaaagtt tttataatca taaactttta ttttcatgaa tgatttatgt
     2461 ggattatttt cataatttag caggtagttt tctatatctt caatataact atcatcaaat
     2521 ggtgtgtgct ggaaataaaa agtttttaca tacatgaata ttttataaag ttcttctttc
     2581 aaaaaatcat atgtatctaa atctctttgt atagcatcca atttttttaa tttttttaca
     2641 tttttaccac aatcctgtac tcttatccat ccactatttt ctttaatttc actaggtaca
     2701 ctttgcatta aagtctgaga tactttactt tttaattccg aaatatcatt aatatttgga
     2761 ctaattagtc tattttcttt aacttttgtc ttaaactcat ctaatttttt agacttttcc
     2821 gcggattcgg tagatgcttt attcatctca aaaacatata taggtttacc taaagattta
     2881 gcaaaattgt actccatttc tgtatagcta atattttctt cactatcaat tgttccataa
     2941 ctagaaccta acaataatat cactgcatct gattcattga tccattgtgt tattatttcc
     3001 cattggcttt tactacttga gttaaaaagt tccatacctg ctggaatatt attactgttt
     3061 aaaactgctt ctactactgc ttgacgctct tctattaaat ctaaataagt tgatgaaata
     3121 aaaatttgat atttaatttt agtattactc atatatgctc ctttaataaa aaatcaattt
     3181 acataaatat atcatatgat aatatccaaa aagactactt aaaatattat ctttttgcat
     3241 tcctctacta accagtgtta taatctagat aacgaaaatg attaacaatt aatgcaccaa
     3301 tccccacact actgcaatag tgtggggatt ttttcgatgc tggcttataa agtcgcctat
     3361 taattatttg ttgcgtttac taagccaata agtataatac gcaacagcac agccactgat
     3421 gactggtgct atgatgtgaa cgaaaatgat tagcaaagta atgcacctcc tctctgcgtc
     3481 tgaattgacg cctgagagat aggcgacctg tatattatat catctccgaa tatacgatga
     3541 tagataactt ccgataagtc gtcttatgtt atataacttt gttttttata gtatcaagac
     3601 aagaagaaac tcgtttcact cgtttcaaaa accctcctga tttttagaga aaaactctct
     3661 tatttcatcg tctttaataa aataatatgc catctttcca tctttataaa aatcaagtac
     3721 ctcattttta tataaaagcc ttaaatgatg tgaagttgaa gcaacactca ttttcaatat
     3781 caaagaaata tcacaaacac acaactcatc ttctttaatc aaagataata tgattttcaa
     3841 tttcttctca tcacaaattt tttctaaaat gttaagtaat ttcttagatt tatcatcttc
     3901 taaaaaactt aaagcattgt taactttatc ctcatgtaca cagatcacat cacaagtatt
     3961 ttcataactc atataaaatc acaccctaaa ttaaaatata aatcctaaaa ttgtttgaat
     4021 agtgtcattt tcaataataa taaataaacc taaagctata taaatgatag ccataatcca
     4081 acgactaaat ttctcaacaa tttctccaat tcctgggata ttagctaatt tttgtgcagt
     4141 aaacaccaag aagaaaatta aaattaaaaa gacaaacaga gtaagtaata aattagtaac
     4201 acttaatgtc acaaaatacg gaacaaataa accaatatta tcggcgccac aacttgctat
     4261 cgtaacaatt gcaaccgtac caactaattt agacaatcct ttttcattca attctttttt
     4321 agctctcttt tctccttcac aatcatcata aatagccact ttaattccaa gataaattgg
     4381 tattaaaccc aataaaccta atatccactt ttctggaaca taatttaata caaaagctaa
     4441 aaacaaacta actaatatta aaataataga ccctaaatat tgaccaacat aaatatttct
     4501 atattctttt ctagtctttg ctctagcaaa aaatattaat aaaattacta ataaatcaac
     4561 tgctgtagca atataaagaa cagcagcagc aacaaccgtt tgaatcataa tacacctcat
     4621 tcaaaaatat ttttgaatgt attataactt atatttttaa ataatcatag gtgctttatt
     4681 ccaattgctt tattgacgtt gagcctcgga acccttaaca atcccaaaac ttgtcgaatg
     4741 gtcggcttaa tagctcacgc tatgccgaca ttcgtctgca agtttagtta agggttcttc
     4801 tcaacgcaca ataaattttc tcggcataaa tgcgtgtcta tgcgtagaca tggagacact
     4861 tcagaattat ggagtgatta catgagttta actatttttc tttattcagt tttaggaagt
     4921 ttattagcaa attatatcta cgaaaaatct tcaaaataaa taactttttc ggttctactt
     4981 tgtacacttt atctacctgg tagacctaat tgttattgct ttacaggtct aaaattcgtc
     5041 gttataatct agttaaatcc cgtaagggcg cacttatacg tcggataaat cgacatgtgc
     5101 aaaaacgtaa tcgaccttcg tcgatttttt tatttcaaaa ttaaagaaac ggcttgagat
     5161 attccgagca gttataaaaa ttaatttgcg ttgaatattg ctactacatt cttgaaaaag
     5221 tgatgtagat ttatagccca taactttttt gaattacatc gacgatacgg cgtcgaaaga
     5281 aaaagctacc tcactttatc tgggggggct tttatttttt atgcccttat tttgaatttt
     5341 aagagggcat tttaaagatt taggggtgat tcatatagtt ttatatctaa aacttatata
     5401 cgcttttaaa acgcaaatat gagccaaata aatatatgct attttcaaaa acaaaaattt
     5461 gagcaaaaac aataactatt ttttagacac tgcccattta catgcaaatt aaaaattagc
     5521 ataaaattct ttaaaacttc cccacgttct tctaaattcc tgcagggctt ttcttatcaa
     5581 aaacttagaa attttaattt aactctaaaa tctccgtaag agcataaggg aaatttgtcc
     5641 ccatcaatga atgggggatc tggcaaagcc agatatttca aggcttcgaa aatgtttttg
     5701 tgtggggtca taaaaagctc aagtgtcaca cttttgtgac actacataca gcatttgtca
     5761 caaaaataag acagcacttt ttttacaaaa aagtaataaa aaaagacatc agttatcact
     5821 aatgccttaa ataataattt tgcttttcaa aattgccgta atcgaatgtg ccttttcttc
     5881 ttcatttgct attttatctt catcacttgt attaattaaa ttgccatctt cagcatcgtc
     5941 taagtttaaa attttatgtt tttatttaag caatccacca taacttaaca tacgttttcg
     6001 atacaaatct ttttctagat cactgacaat ttcttgattt tttcatcgct atcagttaaa
     6061 aagtcagatg atttaacgaa atattttgat gtatctttga ttgttataaa atcatttgaa
     6121 tgattgatta aagatattat attgtttcat gtttttacgg cgcatataaa gtgcatgtgt
     6181 ttcttcaaat tcagttaaaa ttgtttgcat taaataacct tgcattgact tgaatgatta
     6241 ctaatttcat tttcggactc tatatcattc aagtcattca tatcatttat ttcagtattg
     6301 ttagattcag tatagctaag ttcagtatca ttagattctg ttttatcgac ttcttgaagt
     6361 cggtttttcc gacttccttg ccattgctgc tctcaacagt gttttcttgc ttttgaattt
     6421 tataaatatc atcttctgtt acttctggtt taactaaata aagtttattt gtcttattta
     6481 aaccttgtct ttcttgtagt agtaattcgg cttcaattaa gttctttctt tattttaatt
     6541 actttatctt ttttacaatt taatatattt tgtgggtttt catttttgta ataaaaataa
     6601 atattacctg ttttagaatc aacccaacca tttttaattg ataaatctaa acgatctcta
     6661 agaatacccc atgccatttt tgcatcattg gataacttga tatatttagg atttgtaaaa
     6721 aatactttcg gtatttgata aaacttttct ctgtattcct catttatgtt gtaaagttta
     6781 attgacataa taaaaacctc tttccgaatt ttagtttggt aagaggtaat aaaacgctta
     6841 cattttttgt gtttatttaa taatctaggt gcttgcacta agatattatt cattatataa
     6901 tctaagtatc gaaaattata taaataaaca gtttctaaac gttttattac caaaccccga
     6961 ctattaccag tagttggggt ttttgttata ttaaggttat tatagcactt tgaataaact
     7021 ttaaaaaggg aaaatatagg tttataaacc tttgataaac accataaacc ctttacaaac
     7081 ccttgataaa aaggttggcg aatttatatt tttatttgtc gattacttta ttattaatcg
     7141 ttataagctt ataatatttt actaagggtt tataaacatt ttataaaggg ttgatgatat
     7201 gaaaagtgta aaaaggttga gtgaagaatt aggggttagt aagcaaacga tttttaataa
     7261 tattaagaga ttgaatatag agacaataaa acaggaaaac acttcgttta ttaaagaaga
     7321 taccgatata gaaaaaatca ttcaaagagt aaatgaaaat aaaaagaaat atggttttga
     7381 aagtgctact gaagacaaac aaaaaaaaga gtcggataat attaattttg aatctaaaag
     7441 cgatgctcaa atagtagaaa tacttaaaaa tcagattaat actttaaata atcaaattga
     7501 aaaacaagaa agtcgtcatg aaacaacaat tgaattttac agaaaagagt tgcaagaaag
     7561 atcaaaattg cttgagaatc agcaagttct ggcattagag agtaataaaa agattcaaaa
     7621 attagaaaat caattagaaa aagaaaaaca ccttaattat ccctttgata catctactaa
     7681 cgctagacaa aacgttgatg cacaagaaaa aacatatact actagtcctg taaatattaa
     7741 ccgagatcag gaagaaacta aagaaacaga gattcaatat aaggatatat ctggaagtca
     7801 aagcgacgaa agtacacaag gtgaagaagc acaaagagaa gacgtttcag ctaatccaaa
     7861 tgacaatgat agtgatatag aagaaaagag tgaagaaacg gaacctaaaa aggggttttg
     7921 gagtcgtcta tttggtaact aattttaatt aaaaaggtac gacaagttca taaattagcc
     7981 gtgctttttt atgtgaattg aacttctgat aatcatcgat tatgttaacc aaacaaaaag
     8041 ccataaatgc ctatatgacg gcatttatgg ctttttactt tcattatctt ttatgcatct
     8101 tttatacatc gttgatttga cgcgttttca ttcttttgca ttggcaagta ttttgtatct
     8161 ttattcagtt actatttctt ttctccaacc taacaaacca tctttaactc taataatatg
     8221 tttgccacgc cagacacttc ttacttcgaa ataataccat tccccgtttt tgttgaggaa
     8281 ataaatatct tgataacctt ctttaatgac atattttgta gcttcttgtc tttgatcgcc
     8341 aaacattatc aatcccaccc ttatatttat ttatctttaa tatataacaa catttattaa
     8401 tattcatgtt atttcatgga aggagagatt tgttataatg tgaaggtcgt ctatctctca
     8461 gatgtcaatt cggcgtagag aggaggtgcg atttatgaat gaaattcttg ttcacatcat
     8521 gacaacggca atcagtggtt gtctcgttac gttatttggt tattagctcc ataaacgtga
     8581 taaaaaataa tatagacgat taaagccaat tcaccaaaaa accccgaact acggcgaata
     8641 gttcggggtt ttgtgcgttt acaaacgaaa ttcttgttac ttttagtata tatttcatat
     8701 tgccttttgt aaactcttct attcttatca atacatttca aggtgtcgta aaaatacttt
     8761 cctttttcat attgcctgat gtgcattaaa ttttgatttt aaaatcaacc catgaacgaa
     8821 tgaatggccc aaactaaaaa tccggcaaca ggaaagaaaa gccaccaaaa atcataaaga
     8881 aaatcaacta tggaaggtac cctgttactc tctctataat ttccctctaa aataactttt
     8941 ttaaaacgtg catctccttt aattaaatgc tctaaagaga ttccgaataa atcgctcata
     9001 gcaatcaaaa tatctaagga aggatagttt ttggcacttt cccatttaga aacactttgt
     9061 ctggaaacct ttaatatatt ggctaattcc tcttgagacc atccttttaa ttctctctgt
     9121 tcttttatag cttcagctaa tttcataaaa tcactcctta actcaaacta taattaaaat
     9181 aattgaaaag tcacgatact tttagttaac caactcgcaa cgaaaagttg cgttattccc
     9241 aattcagttc aagttgtttt aaaaaatcct ctcgttcttt ctctaattgt gggtcgtaat
     9301 ctttttgagg ttgcttttca tatgaccgtt cttctaacca tttaggcgtc ttttcacgcc
     9361 tcacatattg tcttgattta tctatcttgg acatttgagg ttgtcgtttg ttatgaatgc
     9421 gtttctcagc gtcaaatgtg aactctatcc attcaatttt acgccctttt ttcgctttga
     9481 ttttattgat agtaagatta ttaaatatag aacctaattc aataataata ggtttaaaaa
     9541 catttttgtt aatatcagtc atacgataag atttaggtat atctaaacga tttttaaaat
     9601 catcgatgtg aatttttaaa tagcctgtat gtttgtattg tttaagtaat ctaaacatat
     9661 ttttagaata tgtagattta agcctagtca tttcttttaa ttcaaatttt gtaaaattat
     9721 tagtaattga attcaatatg tgttttaaat ttgaagaagt tgatatttct agatattgtt
     9781 ctcgcttatg gattctataa tgattgaata aaacgaatct ttctattaca tcatcatctt
     9841 catatctaat ggttaaattc aacatctttt tatacacatt atctaaatca ttagcaaatc
     9901 tattaatatt acgtgtttct ggactataat tacttaattt ttttaattca tcaaaagaca
     9961 aacgtaatgt attagtatct tgctctttta atttattaca catcgcaaaa aataaattaa
    10021 tttcagtagc tgtaaatcgc cttaatggaa ctaaattcat ttcattttta tatacaactg
    10081 tctctcctgt catgatacag ccccctttat tacgaaccta aaggagtatc gtttgaatat
    10141 acactcccat ttgaaaactt ttattcacaa taaactactt tattatcaat gtcaaaccat
    10201 aaaaggagta caacttttta aaacactcct tttatgtggc aaaaacactc cttttatgtg
    10261 gcaaaaacac tccttttatg tggcaaaaac actcctttta tgtggcaaaa acactccttt
    10321 aggcattgaa atcccttgtt gctctaggga ttaacaagcc cctaaaaagg tttttaaaaa
    10381 gatttataaa aatatattaa aaagttcgag gggggctacc tatttttcat cctaaaaaat
    10441 aattaacctc aaacaaatgc atttaaatat ctatttttat aatgtataac catcttctct
    10501 atcttcttta aaaatgattt ctcgttcttg tgcttgatat ttcttcttaa agaactgttc
    10561 atcattgtta tctatcgtca ttacttcacg tattttagaa ttgtctaaat gattatcaat
    10621 atgatttatt agtgtatgat aacgctcttc tttcatcata cttttaatga ttttaaaaac
    10681 ttgattgaat aacttaagcg tataatttag ttctttatct ttcttttcat tctctgacaa
    10741 caaataatta taacgttgtg ctaaatcatt aaattcttca accagctttt cattttccat
    10801 atggacacta gtcaattcat taactaaact ttcattttgt ttctctgctt tttttaatga
    10861 cttcccactt ttaatacatt cataatcatc taatatcatc tgtgctgctt taatttgttt
    10921 agtgtatttt tcaaaatcag ttttagtaat tacaatattg cctgtttctt gcttctcttt
    10981 atgaaaccat ccacctacat ttttagtttt aatttcatac atgacactca gaagcttttt
    11041 aagcgtatct aatgattttt ggtagttttg tatcaattta tcattttctt gctttaaata
    11101 atcctctatt tgcttctagc gcatatgcat ttgtttatga tattctgttt tttgtttata
    11161 acggctaact tgatcatgtt tttcttttgt aagttgtcta gaaattcctc gttttaaatc
    11221 atagccttgc ttattaatat acgtattgaa tctatcttgg aattcggtta atgctttttt
    11281 attacctaca acttctttcg cacttaaacg tccatcttta gtaataggaa ctacgccata
    11341 atgcatatgt ggtgttatct catccatatg tactgtcgca tataaaagat tttctttacc
    11401 gtattcttct tccaagaacg ctttagcatg cttaaaaaac tattttgtct cttcttcaga
    11461 taattgatta aaaaacacat tatctgatgt aattaatcca tcaatatgtt taatggcatc
    11521 tgttctaatt ttgcgtttcc ctttataatt tttttcgatt ttctcatcaa tttttttatt
    11581 aaaatcaaac ttagtatcat tgactaaatc atagtttaaa tatgacttac ttaaatcaat
    11641 atctatattt tcataatttt tattttctct ttgaatatgt ctttgaatac ctcttgtatt
    11701 tgtttttgat ttcactttaa caactcgaat aattgaataa gacataataa atcaacttcc
    11761 actgcatatg attataacac ctaaacacag aaaagtttta acatactaga cttattaaaa
    11821 accaaataag tcattaaaaa cgtgtgctct gcgaggcttg ttttttgtca tcataaaaaa
    11881 ggactggaaa atccagtcct taaattaaaa aactcaaaag taatgactaa tcatatttca
    11941 tattgttttt tctctatgta tggctatacc tatcaatatt tcttaacttc taagctcaga
    12001 aatattgact atgacatcaa atcgtttcgc aagctctaaa tcatgcgtta cgacaatcat
    12061 agttttattt tcatcaagta gcttcaataa taaatcaata actatttttc catttttcgt
    12121 atctagtgac ccagtaggtt catcagctaa aatgattttc ggatctttta atattaatct
    12181 tgccaatgct actctttgtt gttcaccacc gcttagagaa ctaacaattc tcttgatatc
    12241 taaatctagg ccgacctttt ttaatacttc tttctttaag ttcatattat cttttttatt
    12301 ctttttgaac tttagggcta aatctaaatt ttgactgatt gtttgatttt caagtaaagc
    12361 aaaattttga aacaaatacc ctaacgtata tctataaaaa tcgactttct tttttagtaa
    12421 cttatcttca atatatatgc ttccttgtga tacatcttcg aacccagcga ttatgttaag
    12481 taaagtagat tttccagcgc cactttctcc aactaaagca tatgattttc ctttttcaaa
    12541 attaaagtta catccgtcta aaatgttttt attacctttt tttacaaaaa cattttcaag
    12601 ttttatcact atcggtcacc tcattttaaa aagctaggaa tatcttttgt aatgtattct
    12661 atcgaacgca catatttccc tttatgattt actttcacat attcttttgt aggatcataa
    12721 cctaaaaaat ccaatttata actctttttt tctccatttt tagagtatac agttatattt
    12781 ctatagtcct gggtatcttt tggaactttg gcataagata ctttttcttt taacagtggg
    12841 ttaaaacgat ctaaatgctc atttctaacc aataacagac taagtatgat gattaatagt
    12901 acaattgtta caataattaa agttcttttc attgtttaaa tctccctcat taaatcttta
    12961 aagtattttt caagatattt aatataagca atttgaagta aatgttgaat aatagcaata
    13021 gacattatta tgaatagtaa tatctttgaa ccaaataaaa tatgcgtagt gtaagctaac
    13081 ataatagaaa gtaagataga aattgttaaa taacgtacat tactgctgaa taatgaataa
    13141 ccatgaattt ttcttaataa tagttgcttt ttattccagc taaaatattg aattgtttca
    13201 aatacagtag ctatcaaaag aatgaaaacg ttaataataa tagtaactat tgttattatc
    13261 atttttgttt tcgtttcatt taattcattt aacacagaat ccttgtaatt agttataccg
    13321 ctaatttctt cttctaggtg attatcttta agcaactgtt taagtgtatc taaatcttta
    13381 aatagatatc caccttgaga aacagcagct aaataaaaat ctcctgttaa atcgtcaagt
    13441 gtcaacaaca ttactattgg agaatctaga tacccaaatt tcaaattagt tgtgcgatca
    13501 aaagaaaaaa cagatacgtt ttttgacagt acttgcacat ctactttttt gttttgttgc
    13561 ttttgaaagt caatccatcc ttggtgattt ttttgaattt cagatttttg atattgtaac
    13621 cttggaggaa taaacacgtt tattttatcc gaatgattgt caatcatttt aaaatcatga
    13681 tttatatttt tatagaaatt cagaaaattg ttattgataa aaaagacatt gccattttca
    13741 ggaatgtaat tgtttttatc gggattggct atattattat tctttaaaag caatccacca
    13801 agttgttcgc ttttcttaat taaattgtat atattagttt ctaaaatttg tttttcttct
    13861 gaatttctaa tattaggaga aatctctaat gtatagtaat tatctaactt ttgccagatt
    13921 ttttcagagt catatatatt ctttaacttc gtataagcat ttaaattttg tgccagtaaa
    13981 aaagatagta ttagcaccat gatacatttg gtgaaggtac ccataaatat tgaaaactta
    14041 tatccttttt tcccttttaa gattaatgga atacttaact tcaaaagaag actatacgaa
    14101 atcagccaca gcaatgtagt aatacaagca aaaacaaaaa gcaacacgat aaatctacga
    14161 ataaacatta agaaatccaa ttctaaattg gctatatgaa tgattaatat attagcaata
    14221 aagaaaatag cggtaagtac tagccaataa atgattttta tatgaatatt atgaaaaata
    14281 atgcgtgtag ttgaaaagcc atgtagcttt tgaatagcat aaaatttcaa attatatcct
    14341 ctgtcatata agaagtacaa aagatataat acgcctaaga atatgaaagg cactaataaa
    14401 tcattatcta tgactaattc aaaaaataat atgtttctat ttatgtattc aacttcagat
    14461 gttaaaccag ctttttttaa ttcactcgta agctcttcta cattgaaatg ttcaccaata
    14521 atataatact ttccttttat ctctctgttt aataaatctg atggagttaa aagtgatgtt
    14581 ttattacgta taaagtcaga attatttcgt tttgagttga aaacaaaaaa ttctttttta
    14641 ttatcaaaat ctttaacgga tttaattatt tgtatatttt gatttttggc gcctgattca
    14701 atgacatcta acacttttga tttactgtta gatttatccc aattagagat tgttaaaata
    14761 ttggaacttt caggtataat ttcttcattt tctttgaaga aaaataaaaa taatagccct
    14821 gaaattaata ataaagtact aaaatctaaa aataatttga attttttcat attgcctctt
    14881 tcaagagaat agacagaatt aagtttactt aattctgtct attctcctta attaatatat
    14941 gtaattagtg aagactataa aatgttttgt ttccacccca agcctttgga gcagatgcct
    15001 tagattgaac accaggtcga gcaacaccac taaaagatga atatttccct actgctgttg
    15061 aaccatgatt tcttttattg tgactataat aagaccatac gtaatgtttt ccaataccat
    15121 ggctccaaac accaccagct acatgtactg ttgcagcttc agctttataa gttacaccta
    15181 ataaagtgcc gaataagatt gtactagcaa tacaactaga aacaaatttc tttttcataa
    15241 aaacacctcc atttaatatt ctttatttat tatagcaaaa ataaataaaa tagagaatga
    15301 gtaaaaataa tctaaaagtg ttttttctgc tctgttgctt gttttgttca tctatatata
    15361 atattaattc tattatcctt aaattaacta tcattaaaca acgatatgac aatgtataat
    15421 aaatacaatt tcactaccta taattcaaca ttatataaac taaagtattt caaataatta
    15481 actgtattaa tactctcatc atgattgcgt tataaacatt cgttaatgag aaaaagagag
    15541 agcatattta cgctctcttt tcttgtctta ttattaaaaa ctcataatag attataatca
    15601 tctgttttga gacgctgtga gaagctctca gttgcattga aacaaagttt attaaatcaa
    15661 atcattatcg tttttaattc tgtaaatcgt ctgccttgtt atatttactt ctttcgcaat
    15721 tttactaatt gattggcctt cttctaacat ttctacaacg cgatgataaa taatacgttt
    15781 ctgtggatct ttagcatttg gtgaataaag taaggggcgc cctttatata cgcctttttc
    15841 cttcgcaact tgaattcctt gcgcttgtcg acgtttactt tcatttctct cttgttctga
    15901 aaccattgct aatatttgaa taattaaatc tttcataaac ttatccagta atggattgcc
    15961 aaccacttca ttcatcatag gtaagctagt aatcattaat tgtacttctt tgtcttttaa
    16021 ataattaacg gtatgaatca cttcatcata attacgacct aaacaatcaa tggattctac
    16081 tacaaaccga tctcccatcc tcaaaaagtt aagtgcttct tgaagtactg gtctattttc
    16141 aatagatttc ccagactgtt tttctgtaaa tattttttca gcacaaaacg tctttaaatt
    16201 ttcaagttgt ctttctaaat tttgatcgtt cgatgatact ctcgcatagc caacaatcat
    16261 tgatttccat ctcataatta atatacaccc taatcatacg tttcagttac tataaattca
    16321 acaattatgt cactttgctt gatatatgag aattatttaa ccttataaat gagaaaaaag
    16381 caacgcactt taaataagat acgttgcttt ttcgattgat gaacacctat aattaaacta
    16441 ttcatctatt atttatgatt ttttgtatat acaatatttc tagtttgtta aagagaatta
    16501 agaaaataaa tctcgaaaat aataaaggga aaatcaggtt ttgatatcaa aattatacat
    16561 gtcaacgata atagaaaata taatacaaac tataagatgt tatcagtatt tattatgcat
    16621 ttagaatatt aaaattcctt cattacactc ttggcggttt cacttatcaa cttatcattt
    16681 ggcttatcac ttttattgtc tttattcgta aaaatgacta aaacaatagg ttcagattgg
    16741 cccttaggat aaacaaaagc aacatcattt ctagaagcat atgttattgc ttgaccactt
    16801 ttatcagcaa ccttatagtc ttttggaaca ccatctttaa ttaaagtgtc tccgttttta
    16861 ttattaaaca ttaaatcaag taagaaattt ttattttttt tgcttaattt tccatttgcg
    16921 ataagtttat ttaaagtctt gccgaaagca gcaggcgttg aagtatcttt tttgctcttt
    16981 ggcgaatagt aatttaattc tatctcatat ctaactggat ttgttacttt atctcctagt
    17041 tcttttagac gttgtttaac ttttttgatt ccaccgattt cttttataat tttattgttt
    17101 gctgtattat cactatatgt cattgaagcc tcaataagtt cttttaaagt gatgtctttt
    17161 cctacatatt tttctaaaat aggagaataa gcaactatat catctttgtt aatatgtact
    17221 tttttattta acttattata aggtacttgt tctaacaaaa tagcactatt tatcgctttt
    17281 gaagtcgaag cataggcaaa tctcttatct gaattaaatt ttacttcctt accactttta
    17341 gtatctaaag cataaacacc aatatgagca ttatattttt tttctaaatc atttaactct
    17401 ttggcatgtg aattgtttga attacatgca cttaaaacta aagccattac aattaaaaat
    17461 attaactttt tcaaaataaa ccctccgata ttacagttgt aatttttaca aaacaataat
    17521 attacaattg taatattgat gtcaattgtt tattataaat atttgaaaga aggtgtcaaa
    17581 atggctaaat tactaataat gagtgtagta agcttttgtt ttatatttct attgttagta
    17641 ttttttaggt acatattaaa acgctatttt aattatagtt taaattataa agtttggtat
    17701 ctaactgtgc ttgctggatt aattcctttt atcccaatta aattctcttt tataaaattt
    17761 aataatgtga ataatcaagc gcccacagtt gaaagtaagt cacacgactt gaaccataac
    17821 ataattacca ccaaacctgt tcaagagttc gcaacagata tccataagtt taattgggat
    17881 tcaattgata atatctgcac agttatttgg atagttttag ttattatttt aagttttaaa
    17941 tttttgaaag ccttattata tcttaaatat ttaaagaaac agtcacttta tctaaacgaa
    18001 aatgaaaaaa ataaaataga tacgatactt ttcaaccatc aatataaaaa aaatattgtg
    18061 attcgaaaag cagaggctat tcaatctcca ataacttttt ggtatgggaa atatattatt
    18121 ttgattccta gttcatattt taaaagtgta attgataaaa gactaaaata tataatactg
    18181 catgaatatg ctcatgctaa aaatagagat actttacatt taattatctt taatatcttc
    18241 tctattatta tgagttacaa tccattagta catattgtaa aaagaaagat aattcatgac
    18301 aatgaagtag aagccgatag atttgtcctt aataatatta acaaaaatga atttaaaact
    18361 tatgcggaat ctattatgga ctccgtatta aaaacctcat ttttcaacaa aaatatatta
    18421 agccattcat ttaatggtaa aaaatcatta ctcaaaaata gattaattaa tataaaagaa
    18481 gccgatctga aaaagcagtc aaaattaatt ctaattttta tttgtatttt tacttttttt
    18541 atcatgataa ttcaaagcca gtttttaatg gggcaatcct taactgatta taattataaa
    18601 aagcccttac aaagcgatta ccaaatttta gatgaaagta aaaattttgg ttcaaatagt
    18661 ggatctttcg ttatgtacag catgaagaaa gacaaatact atatttataa tgaaaaagaa
    18721 agtagaaaaa gatattctcc tgattcaact tacaaaattt atttagcact gtttggactt
    18781 gaccgtcata ttataagtga taaaaattca cgtatgtcat ggaatcataa acattatctt
    18841 ttcgagtctt ggaataagga acaagattta aatacagcaa tgcaaaattc agttaattgg
    18901 tacttcgaac gtattagtaa tcaaatacca aagaactata ctgcggctca actcaagcaa
    18961 ttaaattatg gtaatgaaaa tttgggaagt tataaaagct attggatgga agatagtttg
    19021 aaaatatcta atcttgaaca agtaatagtt tttaaaaata tgatggaaca aaataaccat
    19081 tttagtaaaa aagcaaagaa tcaattatct tcttcattat tgattaagaa aaatgaaaag
    19141 tatgaactgt atgggaaaac aggtacaggt atagtaaacg ggaagtataa taatgggtgg
    19201 tttgtaggtt acgtaattac aaatcatgat aagtattatt ttgctacaca tttatcagat
    19261 ggaaacccgt ctgggaaaaa tgctgaatta ataagtgaaa aaatattaaa aggaatgggt
    19321 gttttaaatg gccaataagc aagttgaaat atctatggct gaatgggatg ttatgaatat
    19381 aatatgggat aaaaaatcag tatcagctaa tgaaattgta gttgaaattc aaaaatataa
    19441 agaagttagt gataaaacga ttagaacatt aatcacaaga ctatataaaa aagagattat
    19501 aaaacgatac aaatcagaaa atatttattt ttactcatca aatattaaag aagacgatat
    19561 taaaatgaaa actgctaaaa cctttcttaa taaactgtat ggaggggata tgaaaagttt
    19621 agtgttgaat tttgcgaaaa atgaagaatt aaataacaaa gaaattgaag aattgcgaga
    19681 tattttaaat gatattagta aaaagtaatt agaggtatgt ttcaaacata atacatatgt
    19741 aaactatgct tgactcttat taaattagtt ttgttaatga catttaaaat atattattaa
    19801 agatgagagt gtacagaaaa taaccatttt ctgtacactc ttcttttatg tctaaataag
    19861 taagaattac ataggattat gtgttcaaaa acccaacaaa aaatctatgt tcataaaaga
    19921 ccttgtaatt aagttatggt acactgaaga tgtatatagg aggtttgtat tttgaaaata
    19981 ggttatgcaa gagtttcaac tggattacaa aatttaaatt tacaggagga tcgattaaat
    20041 acatatggtt gtgaaaagat atttaatgac catatgagtg gttcaaaaag taaaagacct
    20101 ggtttagata aagcaattga atttgcgagg tcaggagata cgattgttgt ttggagatta
    20161 gatagattgg gacgtaatat ggaggattta atcacattag ttaatgagct taacgaacga
    20221 ggtgtaagtt tccatagttt agaagaaaat ataacaatgg ataaatcaag ttcaactgga
    20281 caattattat ttcatttatt cgcagcattt gcagaatttg aacgtaattt aattttagag
    20341 cgttcttcag ctggccgaat tgcagcacgt gctagaggcc gatatggagg cagaccagaa
    20401 aaattaaatc aaaaagattt aaacttactt aagacccttt atgataatgg cacgccaatt
    20461 aagacaattg cagaacagtg gcatgtttca cgtacaacaa tttatcgtta cctcaataaa
    20521 ttggaggaca aggaagatga aaaacaagga gaagtatcta actaattttt ctgaagctaa
    20581 acgtaaaaaa gctactcaaa agtacaatat tataaaacct tttatcctag gcgaacaatc
    20641 tttatcaagt atttctaaaa gtaaagggat tgcgttaagc accctttata ggtggaataa
    20701 gtcatataaa gaacaaggac ttaaaggact
//
