LOCUS       NZ_CP024884             9294 bp    DNA     circular CON 25-NOV-2023
DEFINITION  Klebsiella aerogenes strain AR_0009 plasmid tig00000054_pilon,
            complete sequence.
ACCESSION   NZ_CP024884
VERSION     NZ_CP024884.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN04014850
            Assembly: GCF_002796525.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella aerogenes
  ORGANISM  Klebsiella aerogenes
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 9294)
  AUTHORS   Conlan,S., Thomas,P.J., Mullikin,J., Frank,K.M. and Segre,J.A.
  TITLE     Whole genome sequencing of Klebsiella aerogenes AR_0009
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9294)
  AUTHORS   Segre,J.A. and Mullikin,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-NOV-2017) NIH Intramural Sequencing Center, 5625
            Fishers Lane, Rockville, MD 20852, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: canu v. 1.6
            Genome Coverage                   :: 181x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/25/2023 02:35:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,095
            CDSs (total)                      :: 4,975
            Genes (coding)                    :: 4,898
            CDSs (with protein)               :: 4,898
            Genes (RNA)                       :: 120
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 83
            ncRNAs                            :: 12
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 37 of 77
            Pseudo Genes (incomplete)         :: 37 of 77
            Pseudo Genes (internal stop)      :: 14 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP024884.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..9294
                     /organism="Klebsiella aerogenes"
                     /mol_type="genomic DNA"
                     /strain="AR_0009"
                     /db_xref="taxon:548"
                     /plasmid="tig00000054_pilon"
     gene            complement(join(9195..9294,1..200))
                     /locus_tag="AM336_RS00005"
                     /old_locus_tag="AM336_00005"
     CDS             complement(join(9195..9294,1..200))
                     /locus_tag="AM336_RS00005"
                     /old_locus_tag="AM336_00005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146176.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_001146176.1"
                     /translation="MPYDVEWKQGAIEDVTTLFDYIAENSSLWDAQNVTDRVLAAADKL
                     ADFPRLYEVDSRYGEDVRRISLMGQHVLYDVDDQTRKVRVLAVVGQRQNPHIVL"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(190..453)
                     /locus_tag="AM336_RS00010"
                     /old_locus_tag="AM336_00010"
     CDS             complement(190..453)
                     /locus_tag="AM336_RS00010"
                     /old_locus_tag="AM336_00010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000072676.1"
                     /translation="MSNTTHYENANFLRELAESLPRILPEGGPDKAALLQRLANEELAQ
                     AEYEDQVRAKVTAARADTRPGMTTEQLRQRLHGRYQELRDAV"
                     /name="hypothetical protein"
     gene            complement(759..1178)
                     /locus_tag="AM336_RS00015"
                     /old_locus_tag="AM336_00015"
     CDS             complement(759..1178)
                     /locus_tag="AM336_RS00015"
                     /old_locus_tag="AM336_00015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Exc2 family lipoprotein"
                     /protein_id="WP_001254601.1"
                     /translation="MRRSGSKLCLIAMITATATLTACAPKGSVEQHTRHYVYASDDGFD
                     PNFSTQKADTTRMMVPFFRQFWDMGAKDKATGKSRSDVQQRIQQFHSQEFLNSLQGTTQ
                     FAGTDYRSKDLTPKKSRLLADTISAVYLDGYEGRQ"
                     /name="Exc2 family lipoprotein"
     gene            1581..3266
                     /locus_tag="AM336_RS00025"
                     /old_locus_tag="AM336_00025"
     CDS             1581..3266
                     /locus_tag="AM336_RS00025"
                     /old_locus_tag="AM336_00025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin-like bacteriocin tRNase domain-containing
                     protein"
                     /protein_id="WP_004178188.1"
                     /translation="MSGGDGRGPGNSGLGHNGGQASGNVNGTSGKGGPSSGGGTDPNSG
                     PGWGTTHTPNGDIHNYNPGEFGNGGSKPGGNGGNSGNHSGSSGGGQSSATAMAFGLPAL
                     ATPGAEGLALSVSGDALSAAVADVLAALKGPFKFGLWGIAIYGVLPSEIAKDDPKMMSK
                     IVTSLPADTVTETPVSSLPLDQATVSVTKRVADIVKDERQHIAVVTGRPMSVPVVDAKP
                     TKRPGVFSVSIPGLPSLQVSVPKGVPAAKAPPKGIIAEKGDSRPAGFTAGGNSREAVIR
                     FPKESGQKPVYVSVTDVLTPAQVKQRLEEEKRRQQAWDAAHPEEGLKREYDKAKAELDA
                     EDKNIATLNSRIASTEKAIPGARAAVQEADKKVKEAEANKDDFVTYNPPHEYGSGWQDQ
                     VRYLDKDIQNQNEKLKAAQTSLNEMNESLSRDKAALSGAMESRKQKEKKAKDAENKLNE
                     EKKKPRKGTKDYGHDYFPDPKTEDIKGLGELKEGKPKTPKQGGGGKRARWYGDKKRKIY
                     EWDSQHGELEGYRASDGEHLGAFDPKTGKQVKGPDPKRNIKKYL"
                     /name="colicin-like bacteriocin tRNase domain-containing
                     protein"
     gene            3276..3533
                     /locus_tag="AM336_RS00030"
                     /old_locus_tag="AM336_00030"
     CDS             3276..3533
                     /locus_tag="AM336_RS00030"
                     /old_locus_tag="AM336_00030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cloacin immunity family protein"
                     /protein_id="WP_004152553.1"
                     /translation="MGLKLHIHWFDKKTEEFKGGEYSKDFGDDGSVIESLGMPLKDNIN
                     NGWFDVEKSWVSILQPHFKNVIDISKFDYFVSFVYRDGNW"
                     /name="cloacin immunity family protein"
     gene            3618..3767
                     /locus_tag="AM336_RS00035"
                     /old_locus_tag="AM336_00035"
     CDS             3618..3767
                     /locus_tag="AM336_RS00035"
                     /old_locus_tag="AM336_00035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891188.1"
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="WP_004152552.1"
                     /translation="MKKVKVVFLFILIFSGFLLVACQANYIRDVQGGTVAPSSSSELTG
                     IAVQ"
                     /name="colicin release lysis protein"
     gene            5248..7212
                     /locus_tag="AM336_RS00045"
                     /old_locus_tag="AM336_00045"
     CDS             5248..7212
                     /locus_tag="AM336_RS00045"
                     /old_locus_tag="AM336_00045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004178196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="WP_004178196.1"
                     /translation="MFNTDSLAWKWHIPELARQIYPWVSWLYQEYYGLAGAFLVIGLFF
                     GLAELWAGRMRFVGLSHKERREYADRYKRDNKRPAPFSVLASLDSPGRMVRARRHVWNY
                     AYWLTGAAGLALLGGLVVAVFIESWGETVLRPDLYANADYYLLQPANLFGIAWCAGGLA
                     VGIVLARLLAFLLLDGHFAAADEAVNAKLNQESRRSSQRTGEMTDVRHLHFGEPVPVNA
                     LADFSSEQARQEQAVFLGKDEQGKPVLVPRDTWRKTNIQILGLPGSGKSVMATNALIRC
                     VRDFGDAVVYFDPKGDAWAPHVFRAHCPDFTLLDLRPGKPAQLNLFRDLDQYALKNLLI
                     AGLNLGETGDVADHYRISEQKAAKLIAEQFPQGANIQQVLAAAYALPEALKKDVKGLIT
                     RLENVADLSVLQTDSGIDVAGIINGGGCLYVIGSMDDEAVIRVQKMLFARCAQIIIARD
                     EFREWPHVSVMLDEIKYLLSKYVLNALGTLRSRDCNLLLAHQSLGDFGQCGQDLPAEFV
                     KTTVLDNTPIRWFYRAASLESAQWAAGQTGEIRVDVERRRASREAGNVEHISGDSFIQK
                     EARPLFDVNTLQHLPDGFAVMTGLGVARMAFSSPLRVERREIPLQRFPVLAKTDPLAEF
                     RPPADGGGPKADDDFAGIY"
                     /name="TraM recognition domain-containing protein"
     gene            7212..7943
                     /locus_tag="AM336_RS00050"
                     /old_locus_tag="AM336_00050"
     CDS             7212..7943
                     /locus_tag="AM336_RS00050"
                     /old_locus_tag="AM336_00050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family replication-relaxation protein"
                     /protein_id="WP_004152551.1"
                     /translation="MALELYNVSHAKRQARNAEKTRLTLRWLREELCSTAELVARRLGI
                     AAVQPVYRFLDSLVAKGLLVRTKYPVDGRQVSVWGLTPHGVAFSFDEDEPLADVIPFQP
                     SRVSAAHLPHRLAVQSLRLDMEARGATGWRILHRLSLKGMKVPDALAELDGKTVAFEVE
                     RTVKSRRRYQEVVSGYLFNRKANGIDEIWYICPDRATQVRVQRAILSVDEIVNPQTGEA
                     RKTAELDRERLFACFKFMTTE"
                     /name="MobC family replication-relaxation protein"
     gene            7950..8480
                     /locus_tag="AM336_RS00055"
                     /old_locus_tag="AM336_00055"
     CDS             7950..8480
                     /locus_tag="AM336_RS00055"
                     /old_locus_tag="AM336_00055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008321413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004153058.1"
                     /translation="MALYMVFIEDAEDRNGERCIMPTSEHLEDMVVLAWQTGAYVFCFV
                     DRAQHLAMMKSIGMYDERLNSDEKATYFFTGKNPQWERNKPTGMKLCDYLYRKVERFAI
                     ENGVQVVDAGKCSPEQINAMIDVVSERHGESAVNEKLKAELMREYNSRYFNVPVPELPE
                     DKPARRWWPFGKK"
                     /name="hypothetical protein"
     gene            complement(8508..8687)
                     /locus_tag="AM336_RS00060"
                     /old_locus_tag="AM336_00060"
     CDS             complement(8508..8687)
                     /locus_tag="AM336_RS00060"
                     /old_locus_tag="AM336_00060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_000165971.1"
                     /translation="MTKQEKTALNMAKFIKEQSLLLLDKLNELDMDTPADMCERLHEDA
                     ETLWQVMRDKLGEE"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            8756..9133
                     /locus_tag="AM336_RS00065"
                     /old_locus_tag="AM336_00065"
     CDS             8756..9133
                     /locus_tag="AM336_RS00065"
                     /old_locus_tag="AM336_00065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000312627.1"
                     /translation="MAWVTVRQATELTGKARSSLYRDMAKGRVSYRTEADGGRVVDTSE
                     LIRVYGELRQDETHERDELRLSGETEKMASDALIAEIKALREEVAGLRQEMQSMRLLEH
                     KPETAETPAGTPRRWWPWGKR"
                     /name="hypothetical protein"
     BGC             1..8266
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          complement(3871..4449)
                     /name="ColRNAI_rep_cluster_1857"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="95.361"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          7213..7940
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="1.32e-150"
ORIGIN
        1 agactgatcc ggcgaacgtc ctcgccatag cgtgagtcca cttcatagag tcgcgggaag
       61 tcggccagtt tgtccgccgc agcgagaacc cggtcggtaa cgttctgcgc atcccacagg
      121 gatgaatttt ccgcgatata gtcaaacagc gtcgttacat cctcgatggc tccctgcttc
      181 cattccacgt catacggcat cgcgcagttc ctgataacgg ccatgcaggc gctggcggag
      241 ttgttccgtg gtcatacccg gacgcgtgtc agcacgggcg gcggtcactt tggcgcgaac
      301 ctgatcttca tactctgcct gggccagttc ttcgttagcc agtcgctgca acagcgcagc
      361 tttgtccggg ccaccttccg gcagtatgcg gggcaggctt tcagccagtt cccgaagaaa
      421 gttggcgttt tcgtagtgtg tagtgttgct cattgcggag cctcccgggt taatgcggca
      481 atatgaagga agtttagcag ggggcggtct gaaagaatat ggtcgtgtca gtcaggctga
      541 tgaagcagaa agtcggtaaa aaagggctta cggcatccat tttacgtcaa aacatatgcc
      601 atgcagttgc gtgcataggc atgcattagg ataaaattta tcgggcgcgt ttccggcagt
      661 tttccggggg ggttgttgcc tgttttatcc cgtagccgcc ggaaacgccc tgagcccgtc
      721 tgagcggtgc gcgtaatgac gcgttatggt aaatccactt actgtctgcc ttcatagcca
      781 tcgagataaa cagctgaaat ggtgtcagcc agtagccttg attttttcgg tgtgaggtct
      841 ttgctgcggt aatcggtacc cgcaaattgt gttgtgcctt ggagtgagtt taaaaattcc
      901 tgactgtgaa actgctgaat gcgttgctgc acatcactcc gtgattttcc ggtcgcttta
      961 tcctttgcgc ccatatccca gaactgccgg aaaaaaggca ccatcattcg tgttgtgtca
     1021 gctttctggg tggaaaaatt gggatcaaaa ccgtcatctg aagcatatac gtaatgccgg
     1081 gtatgctgtt ccacgctgcc ctttggagca caggcagtga gagttgctgt cgctgttatc
     1141 atggcgataa gacacagttt gctgccggaa cgtctcatga gcgtctcctt acctttaatt
     1201 cttttttctc attgagttat atatccgcag gctatcttat catcagtttc tgaccgtgtt
     1261 cagtgaccga acaacccgaa ccagaccccc cgtttctttt cctgtcccgg agggggcttt
     1321 ctggtatctc atataatgat ttcagtaaaa catactgagg ccggagaacg gcgccgtttg
     1381 tgctggtttt tgttgcatct ggaggggatt gcgcatggtg tgagtggctg tttttttgat
     1441 cattttcaca aaaacgcaaa tttacagact tgacatgaaa aacaaggcag cgtaattttt
     1501 atactgtata taaaaccagt ggttatatgt acagtatttt attttagttt attgttttaa
     1561 aagtcaaaga ggaaaagtat atgagtggcg gagacggacg aggtccgggt aattcaggtc
     1621 tgggacacaa tggtggtcag gccagtggga atgtgaacgg tacatcaggt aaaggtggcc
     1681 cttcatcagg tggtggtacg gatccaaaca gcgggccggg ctggggtacg acgcatacac
     1741 ctaacgggga tattcataac tataacccgg gggagtttgg taacggcggg agtaaacccg
     1801 gtggtaatgg cggtaacagc ggcaatcata gcgggagctc tggtggcgga cagtcttcgg
     1861 ccaccgcgat ggccttcggt ctgcctgccc tggccactcc gggggctgaa ggactggctt
     1921 tatccgtttc cggcgatgcg ttgtcggccg ctgttgctga tgtgctggct gccctgaaag
     1981 gtccgtttaa gtttggtctg tgggggattg cgatttacgg agtgctgcct tctgagatag
     2041 caaaagatga tccgaaaatg atgtcaaaaa tcgtgacgtc attgccggca gacacggtaa
     2101 cggagacgcc ggtcagctcc ctgccgctgg accaggcgac ggtcagcgtc actaaacgtg
     2161 tggcggatat tgtgaaggac gagcggcagc atattgcggt tgtcaccggc cggccaatga
     2221 gtgttcctgt ggtggatgcg aaaccgacaa aacgtccggg ggtattcagt gtgtcgattc
     2281 cgggtctccc gtctctgcag gtgagcgtac ctaaaggtgt tccggccgcg aaagccccgc
     2341 caaaaggcat tattgctgaa aaaggtgatt cacgtccggc tggttttacg gccggtggta
     2401 actcccgtga ggccgttatt cgtttcccga aagagagcgg acagaaaccg gtctatgtgt
     2461 cggtgacgga tgttcttact ccggcacagg taaaacagcg tctggaggaa gaaaagcgtc
     2521 gccagcaggc atgggacgct gctcacccgg aagaggggct gaaaagagag tatgataaag
     2581 cgaaagctga gctggatgct gaagataaaa atattgcgac cttaaacagt cgcattgcat
     2641 cgacagagaa ggcgatcccc ggtgcaaggg ctgctgttca ggaagccgat aaaaaggtaa
     2701 aagaggcaga ggcaaataaa gatgattttg tgacttataa cccgcctcat gaatatggct
     2761 ccgggtggca ggatcaggtt cgctatcttg ataaggatat tcagaatcag aatgagaaat
     2821 taaaagctgc ccagacatct ttaaacgaaa tgaatgaatc cttatccagg gataaggctg
     2881 cgctttccgg ggcgatggag agccggaaac aaaaggagaa aaaagcgaag gatgcagaaa
     2941 ataaattaaa tgaggaaaag aaaaaacctc gtaagggaac taaagattac ggccatgatt
     3001 attttcctga tcccaagact gaagatatta aggggttggg agagttgaaa gagggtaaac
     3061 ctaaaacccc taaacaaggt ggtggtggta agcgggcccg atggtatggt gataaaaagc
     3121 gtaaaattta tgaatgggat tcccagcacg gtgagcttga agggtaccgc gccagtgatg
     3181 gcgaacacct cggggcattc gatccaaaaa cgggtaagca ggttaaaggg ccggatccaa
     3241 aacgaaacat taaaaaatat ctttaagagg taaatatggg gcttaaatta catattcatt
     3301 ggtttgataa gaaaaccgaa gagtttaaag gtggtgaata ctcaaaagac ttcggtgatg
     3361 atggttctgt cattgaaagt ctggggatgc ctttaaagga taatattaat aatggttggt
     3421 ttgatgttga aaaatcatgg gtttcgatat tacagccaca ctttaaaaat gtaatcgata
     3481 ttagtaaatt tgattacttt gtatcctttg tttaccggga tggtaactgg taagcaaaag
     3541 ttatcaagga tgatttgaaa tacagacttc cggtgttcag ggatgaatac cggggttttt
     3601 aaatacaggg aaggtatatg aaaaaggtaa aggttgtttt tctttttata ttgatttttt
     3661 caggctttct tctggtcgca tgtcaggcaa actatatccg ggatgttcag ggtggaacgg
     3721 tggcaccatc gtcctcctct gaactgacgg ggatcgcggt tcagtagaaa agatcaaagg
     3781 atcttcttga gatccttttt ttctgcgcgt aatcttttgc cctgtaaacg aaaaaaccac
     3841 ctggggaggt ggtttgatcg aaggttaagt cagttgggga actgcttaac cgtggtaact
     3901 ggctttcgca gagcacagca accaaatctg tccttccagt gtagccggac tttggcgcac
     3961 acttcaagag caaccgcgtg tttagctaaa caaatcctct gcgaactccc agttaccaat
     4021 ggctgctgcc agtggcgttt tgcgtgcttt tccgggttgg actcaagtga acagttaccg
     4081 gataaggcgc agcagtcggg ctgaacgggg ggttcttgct tacagcccag cttggagcga
     4141 acgacctaca ccgagccgag ataccagagt gtgagctatg agaaagcgcc acacttcccg
     4201 caagggagaa aggcggaaca ggtatccggg aaacggcagg gttggaacag gagagcgcaa
     4261 gagggagcga ttcatcggaa acggtgatga tctttaagtc ctgtcgggtt tcgccactcc
     4321 tgactgattc atggttgagc caccggctcc cacagatgca ccgaaaaagc gtctgtttat
     4381 gtgaactcag tcaggagggc ggagcctatg gaaaaacgcc acctgcgtgg ccttgccgtt
     4441 ttgcctcaca tgttagtccc ctgcttattc acggaatctg tgggtaactt tgcatgtgtc
     4501 cgcagcgccc gccgcagtct cacggccgga gcgtagcgac cgagtgagcg aggaggcgca
     4561 atttccccgg cacctacaag acggacaccg gacgcgctga tgtggcatat tgtcccctga
     4621 ttaagtcttt atattccctg ataataaatt accaggatag gtgaatcata tcggtttttc
     4681 gctgaacatt ttacgttaac ctatctctgt tgcttttttc tccttacgga gaaatacagg
     4741 tcatccccgc gagggcgtgg ctgacctcag ggggatatcc cctgcttacg ctggctggac
     4801 gccaccgacg cacggtctct ccccctcttt ctggctccgt ccggctggac gccggccacg
     4861 ccagaaattc acccggcccc cgtcaggctc acgcctgacc acccacaaaa atccacggtg
     4921 ctggacgcac ctggcgaagc agcaaagctg ctcctgattt tgcgggtggt cagccgctcg
     4981 ctatggcgaa ctctgacggg ggccggaaca ccggaaaaga ccgcactggg gtgccgcctt
     5041 ttcctctcac acgctggggc gtgctcgttg ttcctccggg gctgcgcctt ttccgcatgg
     5101 ggcggaaaga ggctggcctc cgtggtgaaa gctgaacgca atcaccacgg acgtgaccgc
     5161 cgccgccatg ccttggggca tgtccgcggc ttgtgcagcg ggggctgcac atcacgccgg
     5221 caaaccatcg tctgaaggag agagaacatg tttaatacgg attcgcttgc ctggaagtgg
     5281 cacattccgg agctggcccg gcagatttat ccgtgggtca gctggctgta ccaggagtat
     5341 tacggtctgg ccggggcttt cctagttatc ggcctgtttt tcggtctggc tgaactttgg
     5401 gccggacgga tgcgttttgt ggggctgagt cataaggagc gacgggagta tgccgatcgc
     5461 tataagcgcg ataataaacg gccagcgcca ttttcggtgc tggcctcgct ggattcgccc
     5521 gggcggatgg tcagggcacg tcgacatgtc tggaactacg cgtactggct gaccggcgcg
     5581 gccggtctgg cccttctggg ggggctggtt gtcgccgtgt ttatcgagag ctggggagaa
     5641 accgtcctgc gtccggacct ctacgcaaac gcagattatt acctgctgca gccggctaac
     5701 ctgttcggga ttgcctggtg cgcgggcggg ctggctgtcg ggattgtgtt ggcgcggctg
     5761 ctggcgttcc tgctgcttga cggtcatttt gcggctgctg acgaggcggt gaacgcgaaa
     5821 ctgaatcagg agagccggcg cagcagccag cggacaggag agatgaccga cgtgcgccac
     5881 ctgcatttcg gggagccggt accggttaat gcgctggccg atttttcctc ggagcaggcc
     5941 cggcaggagc aggcggtgtt tctgggtaag gatgagcagg gcaagccggt gctggttccg
     6001 cgtgatacct ggcgcaagac caacattcag atcctcggcc tgcccgggag cggcaagagc
     6061 gtgatggcca ccaacgcgct cattcgctgc gtacgcgatt tcggggacgc ggtggtgtac
     6121 ttcgacccca aaggggacgc atgggcgccg cacgtcttcc gggcgcactg tccggacttc
     6181 accctgctgg atctgcggcc ggggaaaccg gcgcagctga atctgttccg cgatctcgac
     6241 cagtacgcgc tgaaaaacct gctgattgcc gggcttaacc tgggcgagac cggcgacgtg
     6301 gcggaccact accgcatcag cgagcagaaa gcggcgaagc tgattgcgga gcagtttccg
     6361 cagggggcaa acattcagca ggtgctggcg gcggcgtacg cgctgccgga ggccctgaaa
     6421 aaggacgtga aggggttgat cactaggctg gaaaacgtcg ctgacctgag cgtcctgcag
     6481 acggacagtg gcatcgatgt ggcggggatt atcaacggcg gcggctgcct gtacgttatc
     6541 ggctcgatgg acgacgaggc ggtgatccgt gtgcaaaaaa tgctgtttgc ccgctgcgcg
     6601 caaatcatca ttgcgcggga cgagttccgg gagtggccac acgtcagcgt gatgctcgat
     6661 gaaattaaat atctgctgtc gaagtatgta ctgaacgcac tggggacgct gcgcagccgg
     6721 gactgcaatc tgttgctcgc gcaccagtcg ctgggcgatt tcgggcagtg cgggcaggat
     6781 ctgcccgctg aatttgtgaa aaccacggta ctggataaca cgccgatccg ctggttttac
     6841 cgggcggcca gcctggagtc cgcgcagtgg gcggcggggc agaccgggga aatcagggtg
     6901 gacgtggagc gccgccgtgc cagccgggag gcggggaacg tggagcatat cagcggggac
     6961 agcttcatcc agaaggaggc gcggccgctg tttgacgtga acaccctgca acacctgccg
     7021 gacgggttcg cggtcatgac cgggctgggt gtggcccgga tggcgttcag cagtccgctg
     7081 cgggttgagc gccgggaaat cccgttgcag cgtttcccgg tgctggcgaa aaccgatccc
     7141 ctggcggagt tccggccccc ggccgacggc ggcgggccga aagcggatga tgattttgcg
     7201 gggatttact gatggcgctg gagctgtaca acgtcagcca cgcgaaacga caggcgcgga
     7261 acgcggagaa aacccggctg accctgcgct ggttgcggga agagctgtgt tccacggcgg
     7321 agctggttgc gcggcggctg gggattgcgg cggtgcagcc ggtctaccgc ttcctcgaca
     7381 gcctggtggc gaaagggctg ctggtccgga ccaaatatcc ggtggacggc cgtcaggtca
     7441 gcgtgtgggg gctgacgccg catggcgtgg cgttctcgtt cgacgaggac gaaccgctgg
     7501 cggatgttat tccgtttcag ccgtcaaggg tgtcggcagc acatctgccg caccggctgg
     7561 ccgtgcaatc cctgcgcctt gatatggaag ccagaggggc caccggctgg cgcattctgc
     7621 accgtctgag tcttaaaggc atgaaagtgc cggacgccct ggcggagctg gacggtaaaa
     7681 cggtggcgtt tgaggtggag cgcaccgtca agagccgtcg ccggtatcag gaagtggtgt
     7741 ccgggtatct gttcaaccgc aaagctaacg gcatcgatga aatctggtac atctgcccgg
     7801 accgggcgac gcaggtcagg gtgcagcggg caatcctgtc ggtggatgaa atcgtgaacc
     7861 cacagaccgg cgaggcccgc aaaacggcag agctggatcg tgaacggttg tttgcgtgct
     7921 ttaaatttat gacaacggag tgagggatta tggcgctgta catggtattt attgaagacg
     7981 cggaggaccg gaacggcgag cgctgcatca tgccgaccag cgagcatctg gaagatatgg
     8041 tggtgctcgc ctggcagacc ggggcgtatg ttttctgttt tgtcgaccgg gcccagcatc
     8101 tggcgatgat gaaatccatc gggatgtatg acgagcggct caacagcgac gaaaaagcca
     8161 cgtacttttt cactggtaaa aatccgcaat gggaacggaa caaacccaca ggaatgaagc
     8221 tgtgtgatta cctctatcgc aaggtggagc ggttcgccat cgagaacggt gtgcaggtgg
     8281 ttgatgccgg gaagtgctca ccggagcaga ttaacgcgat gattgacgtg gtgagtgagc
     8341 ggcacgggga aagcgcggtg aacgagaagc tgaaagcgga gctgatgcgg gaatataaca
     8401 gccgctattt taacgtgccg gtacctgaac tgccggagga caaacctgcc cgccggtggt
     8461 ggccgttcgg caaaaaataa atgccagcac cggccatgcc ggtgctgtta ttcctccccg
     8521 agcttatccc gcatcacctg ccagagtgtt tccgcatcct cgtgtagccg ctcgcacatg
     8581 tcggccgggg tatccatatc cagctcattc agtttatcga gcaatagcag cgactgctcc
     8641 ttaataaatt tagccatatt gagggctgtt ttttcctgtt ttgtcatgat tctttccttc
     8701 cgggcatggt gtgcgcctgt caggtatact gtctcaaaaa tagcggggtg agacaatggc
     8761 gtgggtgacg gtgagacagg cgacggaact gacgggtaaa gcccgaagtt ccctgtatcg
     8821 ggatatggcg aaaggccgcg tatcataccg tacggaagct gatggcggcc gggtggtgga
     8881 taccagcgag cttatccggg tgtacggtga gttaagacag gatgagactc acgagcggga
     8941 cgagttgaga ctgtcgggtg agactgaaaa aatggcctcc gacgcgttga tcgcggagat
     9001 aaaagcactc agggaggagg tggccgggct acggcaggaa atgcagtcca tgagactgct
     9061 ggaacacaaa ccggagacag cagagacccc ggccggaaca ccgcgccggt ggtggccgtg
     9121 gggaaaacgc tgacgcgctg tgcttgtcca accggcgacg gccacgcaat gaattgcgtc
     9181 cccgtcaccg gttattagag aacaatatgg ggattctggc gctggccgac cacggccaga
     9241 acccggactt ttctggtctg gtcatcaaca tcatagagga catgctgtcc catc
//
