LOCUS       NZ_CP024810            16882 bp    DNA     circular CON 21-MAR-2024
DEFINITION  Staphylococcus haemolyticus strain 83131A plasmid p83131A-A,
            complete sequence.
ACCESSION   NZ_CP024810
VERSION     NZ_CP024810.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN08013134
            Assembly: GCF_002906595.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus haemolyticus
  ORGANISM  Staphylococcus haemolyticus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 16882)
  AUTHORS   Couto,N., Chlebowicz,M., Raangs,E.C., Friedrich,A.W. and Rossen,J.W.
  TITLE     Complete Genome Sequence of Two Methicillin-Resistant Staphylococcus
            haemolyticus Isolates of Multilocus Sequence Type 25, First Detected
            by Shotgun Metagenomics
  JOURNAL   Genome Announc (2018) In press
REFERENCE   2  (bases 1 to 16882)
  AUTHORS   Couto,N., Raangs,E.C., Chlebowicz,M.A. and Rossen,J.W.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-NOV-2017) Medical Microbiology, UMCG, Hanzeplein 1,
            Groningen, Groningen 9700 RB, Netherlands
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 17-SEP-2017
            Assembly Method                   :: Unicycler v. v0.4.1
            Assembly Name :: Hybrid assembly of Staphylococcus haemolyticus
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 196.0x
            Sequencing Technology             :: Illumina MiSeq; minION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002906595.1-RS_2024_03_21
            Annotation Date                   :: 03/21/2024 05:00:33
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,548
            CDSs (total)                      :: 2,464
            Genes (coding)                    :: 2,389
            CDSs (with protein)               :: 2,389
            Genes (RNA)                       :: 84
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 34 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 14 of 75
            Pseudo Genes (multiple problems)  :: 9 of 75
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP024810.1.
            Bacteria and source DNA available from John W. Rossen University
            Medical Center Groningen Department of Medical Microbiology EB80
            Hanzeplein 1 PO BOX 30.001 9700 RB Groningen The Netherlands.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..16882
                     /organism="Staphylococcus haemolyticus"
                     /mol_type="genomic DNA"
                     /strain="83131A"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1283"
                     /plasmid="p83131A-A"
                     /geo_loc_name="Netherlands: Groningen"
                     /lat_lon="53.13 N 6.33 E"
                     /collection_date="2016-10"
                     /collected_by="UMCG"
                     /subtype="ST25"
     gene            1..969
                     /locus_tag="CUZ62_RS12610"
                     /old_locus_tag="CUZ62_12665"
     CDS             1..969
                     /locus_tag="CUZ62_RS12610"
                     /old_locus_tag="CUZ62_12665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_002497508.1"
                     /translation="MSNFNIKEIQKEKFYRLPKVFFTNPKYTKLSNDAKITWSILRDRL
                     DLSIKNNWIDENGDIFFIYTNEKLKQILNISSPNKLSKIKKELTRADLFSQIRVGLNKP
                     NKLYLKKPEVTKADVYYITQQENDVEQQYSTDVSNSYIQKYDNDTSGNIKMIHHDISKK
                     YTNDTDYNDTDYIKTENNDMDDLNDKKSTYPSNHTNHSNHDNSNFNNEALKFQLLEELP
                     QSIQNYLSNFEVAEIKLIKSVLLKAKTSFNNSIDAYYLLEDMEFEIVSVLKRFKATLIQ
                     KNETVEAMQGYLMKSLKSEFAEVHTLNKRRDHLPITSLFNQ"
                     /name="replication initiator protein A"
     gene            complement(1193..1432)
                     /locus_tag="CUZ62_RS12615"
                     /old_locus_tag="CUZ62_12670"
     CDS             complement(1193..1432)
                     /locus_tag="CUZ62_RS12615"
                     /old_locus_tag="CUZ62_12670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002505615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3847 domain-containing protein"
                     /protein_id="WP_002449925.1"
                     /translation="MNDFQNLKKTNAAIEKAELRKHRLKNLDRKERAHRLIRKGAMLEK
                     YFECEHLSPDETEELLKMYSKYINTNKPNKFKKK"
                     /name="DUF3847 domain-containing protein"
     gene            complement(1437..1718)
                     /locus_tag="CUZ62_RS12620"
                     /old_locus_tag="CUZ62_12675"
     CDS             complement(1437..1718)
                     /locus_tag="CUZ62_RS12620"
                     /old_locus_tag="CUZ62_12675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002489259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002449920.1"
                     /translation="MSKIKQTDISKLSQLEQQIEQLKEQKKQQEAQLSNKIGGYFLKKL
                     NLNMINSNDELYKIMDKVIEEFNKDIEQNNSNGNNENLKENEINQNSK"
                     /name="hypothetical protein"
     gene            1922..3844
                     /locus_tag="CUZ62_RS12625"
                     /old_locus_tag="CUZ62_12680"
     CDS             1922..3844
                     /locus_tag="CUZ62_RS12625"
                     /old_locus_tag="CUZ62_12680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /protein_id="WP_053040563.1"
                     /translation="MEKGYFMLRVTNINRATKNIVASASYRSDEALYSERTDEKIKFRN
                     HTVKPESMILTPQNAPEWTKDRQRLWNEVDKVEKHNAKTNNPRLAKEILLSLPNDFDRE
                     VQTELTKDFIKSEFVDKGMVADISIHRDDMNNPHAHVLLTQRPFNSDGTWGKKTKTRTQ
                     YDENGNAILNKNGNKVRKQERFADFDFKEVRKHWELKLNQYSEREQSLRRYDSRSFEAQ
                     GLEKIAEIPLTREEYRLEQNEKKRCEKEGIEYQPVTYYGQKNEQIRRYNRGEVSQLFSD
                     KEKEQAQNEIRLFIQNANNQVSENEQSYSILFDRYKHDVGYSEAKETIKNTFDSASTFG
                     RKIQNDLLKNEIKRSHLKFYADNYDTNYQFRREVENKGYSQQEFINTVKSNFKELLNEK
                     NKLESREEKRKEIYQSAKDVYLTEIDKNNLIVQQMYPKSHNQFSNDEKAFIVDEAQKGN
                     IIKASNVQYLFKQNNYIPSNVFLEDTYKKASKDIFFSERQLKNLEKDSFEYNVELQFIK
                     EKEKEIDSYKEHIDDDLRIDIGDKNFEKVKDQTPNEKVQLLIKLEKYNNVDQKEVIEKH
                     INRIDINDNDNHIEHENEQSNHINLPTINASDFLMYYANETEKQNNINHNKKKKKQERN
                     NQMRR"
                     /name="MobA/MobL family protein"
     gene            complement(4132..4299)
                     /locus_tag="CUZ62_RS12915"
     CDS             complement(4132..4299)
                     /locus_tag="CUZ62_RS12915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002469039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002449919.1"
                     /translation="MKKKLPLVLSFVLAGLIVIGQTGFTQGSDYDQRMDNMMNECTNFM
                     QSFDDNNENK"
                     /name="hypothetical protein"
     gene            complement(4329..4559)
                     /locus_tag="CUZ62_RS12630"
                     /old_locus_tag="CUZ62_12685"
     CDS             complement(4329..4559)
                     /locus_tag="CUZ62_RS12630"
                     /old_locus_tag="CUZ62_12685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002449928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="WP_002449928.1"
                     /translation="MGMGHMMGGMGFIGMIFWIIILGLLFYGVYILIAKASEKPKGVRS
                     DDSLQILKERLAQGEINEDEYEKLKKVLKKD"
                     /name="SHOCT domain-containing protein"
     gene            4821..5438
                     /locus_tag="CUZ62_RS12635"
                     /old_locus_tag="CUZ62_12690"
     CDS             4821..5438
                     /locus_tag="CUZ62_RS12635"
                     /old_locus_tag="CUZ62_12690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017465246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="WP_053040565.1"
                     /translation="MIQTIVTAAILYIVTALDLLVILLMFFARAKTRKEYRDIYIGQYV
                     GSVTLIVISLFFAFVLNYVPEKWILGLLGLIPIYLGIKVAIYGDSDGEERAKKELNEKG
                     LSKLVGTIAIVTIASCGADNIGVFVPYFVTLSVTNLLITLFVFLILIFVLVFTAQKLAN
                     IPGVGEIVEKFGRWIMAVIYIALGLFIIIENDTIQTILGFIF"
                     /name="CadD family cadmium resistance transporter"
     gene            5457..5804
                     /locus_tag="CUZ62_RS12640"
                     /old_locus_tag="CUZ62_12695"
     CDS             5457..5804
                     /locus_tag="CUZ62_RS12640"
                     /old_locus_tag="CUZ62_12695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_053040564.1"
                     /translation="MSYKNACDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNDVLDFYKKGKMAYYFIKDDEI
                     REFFSKNQKGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            5971..6066
                     /locus_tag="CUZ62_RS12645"
                     /old_locus_tag="CUZ62_12700"
     CDS             5971..6066
                     /locus_tag="CUZ62_RS12645"
                     /old_locus_tag="CUZ62_12700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_000493114.1"
                     /translation="MFSTLFVTIIAPIIVGVILTLFSHWLNNREK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            6239..7018
                     /locus_tag="CUZ62_RS12650"
                     /old_locus_tag="CUZ62_12705"
     CDS             6239..7018
                     /locus_tag="CUZ62_RS12650"
                     /old_locus_tag="CUZ62_12705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002505091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_053022574.1"
                     /translation="MSIVTNENEEAVIAILKFVHPNYAEDFENDNLYFNNLQRFHEIEH
                     NEIGDKLEGVISNKLGNKYAPNDEVEMYIRNLEVPNSKIHKVNVKEVTLKNTSDIVKEF
                     KICCFSIIRMKDLVECDDGKYRLNQEFVRKMNGIIDNRNIYVTIHLKDFINKLVKTFSE
                     KDTYFKAGIVEYFEDKHPLFYKIESGKKLIVKDFINASFYKTSQYDSQKEYRILTYKLK
                     ENKLKIEGLYDKFQKLENLKQLAINFYTEEEYRNLNK"
                     /name="hypothetical protein"
     gene            complement(7242..7778)
                     /locus_tag="CUZ62_RS12655"
                     /old_locus_tag="CUZ62_12710"
     CDS             complement(7242..7778)
                     /locus_tag="CUZ62_RS12655"
                     /old_locus_tag="CUZ62_12710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011276563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_011276563.1"
                     /translation="MNFIAWLIIFCEIAFWFVILLGLVTRYILNQQTLGLFFLALTPII
                     DLILIITTVVDLMNGATAEMPHAIAAVYISISLVFGKSMINWADDRFRYYVMKQGSKPY
                     KLDGLDYSKNYAKSWLKHLLSYIIGTGILHLVVYLINDKSRTEAMDGVIHIWTIVIIID
                     LIICISYFVWPPKRN"
                     /name="hypothetical protein"
     gene            complement(7792..8373)
                     /locus_tag="CUZ62_RS12660"
                     /old_locus_tag="CUZ62_12715"
     CDS             complement(7792..8373)
                     /locus_tag="CUZ62_RS12660"
                     /old_locus_tag="CUZ62_12715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001124173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator C-terminal
                     domain-containing protein"
                     /protein_id="WP_011276564.1"
                     /translation="MPKIINHKEKKKQIIQYAFDSIVEKGVKGSTVRQIAKLADMTPGQ
                     IRYYFPNHSELLNAVMSTVELKVRRRIEAIFKSENLTTIDKAKASLLTVLPLDKERLAD
                     MEVWMAFRNDIHEYGQSTLDDGLDQLCNSILTLLKNDHLLKNNVNIHLNSMKLHALIDG
                     LALHKLLNPNGVSNDDIQIIVDEEIVRLTQ"
                     /name="TetR family transcriptional regulator C-terminal
                     domain-containing protein"
     gene            8578..9171
                     /locus_tag="CUZ62_RS12665"
                     /old_locus_tag="CUZ62_12720"
     CDS             8578..9171
                     /locus_tag="CUZ62_RS12665"
                     /old_locus_tag="CUZ62_12720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690636.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690636.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTHGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLNLLKTLYDNGTPI
                     KTIAEQWQVSRTTIYRYLNKLEDKEDEKQGEVSN"
                     /name="recombinase family protein"
     gene            9143..10585
                     /locus_tag="CUZ62_RS12670"
                     /old_locus_tag="CUZ62_12725"
     CDS             9143..10585
                     /locus_tag="CUZ62_RS12670"
                     /old_locus_tag="CUZ62_12725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mu transposase C-terminal domain-containing
                     protein"
                     /protein_id="WP_053032522.1"
                     /translation="MKNKEKYLTNFSEAKRKEATQKYNIIKPFILGNQSLSSISKNKDI
                     ALSTLYRWNKLYKEEGLTGLIHNTRVDKGDHKLEQNIIDEIKRLSLKNKRNSIATIHRK
                     IVNYCIENNFDKPSYKQVYSIIKAMPKSVIDFSHQGEKYYQNKYDLIQIRESSRPNEIW
                     QADHTLLDIYILDQTGNINRPWLTIIMDDYSRAIAGYFISFEAPNAQNTALTLHQAIWN
                     KNNTNWPVCGIPEKFYTDHGSDFTSHHMEQVAIDLKINLMFSKVGVPRGRGKIERFFQT
                     VNQTFLEQLPGYINNNDTPSDLIDFQNFEEKLRYFLIEDYNQKEHSVIQSTPINRWNSH
                     HFFPNMPSSLEQLDLLLLEIPKSRKIHSDGIHFQGFRYSNTNLAAYVGEYVLIRYNPND
                     MAEIRVFYRDEFLCTAISPDLADYSIDIKDIQHARSQRRKHLKQNIASPSTTDLIKEEK
                     NYGYSPQETTKNVKKLKRYRND"
                     /name="Mu transposase C-terminal domain-containing protein"
     gene            10578..11393
                     /locus_tag="CUZ62_RS12675"
                     /old_locus_tag="CUZ62_12730"
     CDS             10578..11393
                     /locus_tag="CUZ62_RS12675"
                     /old_locus_tag="CUZ62_12730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019467708.1"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_000160701.1"
                     /translation="MTKHQNFIETKEYKRFAEFCDACIKYQYIGICYGQPGVGKTLSSR
                     YYTNWNTIEKQVNHRGWEDLASKTTDDILSVNKIFYTAPAEKQTRLSNDLYSISASIDL
                     GQKLHIVNKYGHDHSKHYSDMFKYIDLIIVDEIDRLKVQHLEQLRAIYDEHNLAMIFIG
                     MPGIEKKLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWQDLGFDLKLEDFTDYEAIT
                     TIIKITKGNFRLIHRLFAQIDRIMDINGLDKISTEVVETARDSLVIGIR"
                     /name="AAA family ATPase"
     gene            11545..12153
                     /locus_tag="CUZ62_RS12680"
                     /old_locus_tag="CUZ62_12735"
     CDS             11545..12153
                     /locus_tag="CUZ62_RS12680"
                     /old_locus_tag="CUZ62_12735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002474535.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_011276566.1"
                     /translation="MIIGYARVSSIDQNLERQLDNLKTFGVEKIFTEKQSGKSVENRPV
                     FQEALNFVRMGDRFVVESIDRLGRNYDEVINTVNYLKDKEVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIIQILAMVSEQERNENKRRQAQGIQVAKEKGVYKGHPLLYSTNAKDPQKRI
                     IYHRVVEMLEEGQAISKIAKEVNITRQTVYRIKHDKGLS"
                     /name="recombinase family protein"
     gene            complement(12290..13075)
                     /locus_tag="CUZ62_RS12685"
                     /old_locus_tag="CUZ62_12740"
     CDS             complement(12290..13075)
                     /locus_tag="CUZ62_RS12685"
                     /old_locus_tag="CUZ62_12740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002478743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_011276567.1"
                     /translation="MPVLVLFIETILVTIFMIGSMMGVFNNSISPWIFVIFWVASIVIL
                     LGTIMIRRYSKGKYKKELTIYENSPNLYEKEYFYQAPLYIFDGIHIKVHGMSDTIWTPY
                     FNNNLQKWLSVFDIFPVYGVKLTSVDHTIILKRTKLWSLRPHYRVFIDEEEVGMLQMIR
                     LLKGGIKQQTPYIFSSSNDTYKFSNPYFSTKTVITGKENNEILTAQRSFFDLGKNLVTR
                     RRGEKHNIVIEANDTQIPYPHELWITLYIQVMINKQKEQ"
                     /name="hypothetical protein"
     gene            13186..13524
                     /locus_tag="CUZ62_RS13085"
                     /old_locus_tag="CUZ62_12745"
                     /pseudo=""
     CDS             13186..13524
                     /locus_tag="CUZ62_RS13085"
                     /old_locus_tag="CUZ62_12745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049146.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            13529..13714
                     /locus_tag="CUZ62_RS12695"
                     /old_locus_tag="CUZ62_12750"
     CDS             13529..13714
                     /locus_tag="CUZ62_RS12695"
                     /old_locus_tag="CUZ62_12750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011276570.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_011276570.1"
                     /translation="MKNRIREYRKQKRISQEALSKELKVSRQTINAIENNKYDPTLTLA
                     FKLAKLFDTTVDELFS"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(13841..13966)
                     /locus_tag="CUZ62_RS13150"
     CDS             complement(13841..13966)
                     /locus_tag="CUZ62_RS13150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019469853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_011276571.1"
                     /translation="MEILIKIIDIIVAIVSTFTDETSKYLAKLKEKRDKKKERKK"
                     /name="hypothetical protein"
     gene            complement(14294..14578)
                     /locus_tag="CUZ62_RS12705"
                     /old_locus_tag="CUZ62_12760"
     CDS             complement(14294..14578)
                     /locus_tag="CUZ62_RS12705"
                     /old_locus_tag="CUZ62_12760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002501673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_033080160.1"
                     /translation="MSNLLTFAPAILYAIQYFLSKTGNKIIGGIVPILFIVALVFLYTT
                     GKLGLNIWGTLILGVIGLLFLLGQWSRAQKDNKKKEQKELDKMISKDLK"
                     /name="hypothetical protein"
     gene            complement(14581..14880)
                     /locus_tag="CUZ62_RS12710"
                     /old_locus_tag="CUZ62_12765"
     CDS             complement(14581..14880)
                     /locus_tag="CUZ62_RS12710"
                     /old_locus_tag="CUZ62_12765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002509682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2089 family protein"
                     /protein_id="WP_033080161.1"
                     /translation="MKNNDIPKWMMNLEKEDFEFIKNFVVNSGSLKALAKYYEVSYPTV
                     RNRLNSVIERIESAKDNEESSLVNYVKKLAIEEKLDLNDAKQLLEIYSHEKEIE"
                     /name="DUF2089 family protein"
     gene            complement(15298..15444)
                     /locus_tag="CUZ62_RS13090"
     CDS             complement(15298..15444)
                     /locus_tag="CUZ62_RS13090"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_224743151.1"
                     /translation="MEHPIQTATMDSEVKKEDKNGVYLRMERYFDESIRSANWIGKDVF
                     KYH"
                     /name="hypothetical protein"
     gene            complement(15710..16399)
                     /locus_tag="CUZ62_RS12720"
                     /old_locus_tag="CUZ62_12775"
     CDS             complement(15710..16399)
                     /locus_tag="CUZ62_RS12720"
                     /old_locus_tag="CUZ62_12775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002440810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_002497507.1"
                     /translation="MKSMKKIADELNVTKMTVYNNAKKANVKFQKIDNVNYLSSEDEIV
                     VVNRIKKNQKKSIDAESKINEKNSDNDNNQVKDETIKQLYIQLDIYKEQANRDKEQINT
                     LNRLLENQQVLALESNKKIQKLESQLEEERQLNYSFDTATNNRQNINPKEATFTKEPQN
                     ANQQQKKSQPTEVNHKNIAKEKKDDSINEDELTNEDKFVEETKNDPDDNREVEPPKKGF
                     WSRLFGN"
                     /name="DUF536 domain-containing protein"
     Typing          2..969
                     /name="rep_cluster_1110"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="95.052"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          1923..3775
                     /name="MOBQ"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="92.233"
                     /coverage="97.0"
                     /evalue="0.0"
ORIGIN
        1 atgtctaatt ttaatattaa agaaatccaa aaagaaaaat tctatcgatt gcctaaagta
       61 ttttttacaa atcctaaata tactaaattg tccaatgatg caaaaataac ttggtcaata
      121 ttaagagatc gtttagattt atctataaaa aataattgga tagatgaaaa tggagatata
      181 ttctttatat atactaacga aaagttaaaa caaatcctaa atattagtag cccaaacaaa
      241 ttatctaaaa taaagaagga attaactcga gctgatttgt ttagtcaaat cagagtagga
      301 ttaaataaac ccaataaact gtatctaaaa aaacctgaag taacaaaagc tgatgtatat
      361 tacattacac aacaagaaaa tgacgtagaa cagcaatatt ctacggatgt atcaaattca
      421 tacatccaga aatatgataa tgatacatca ggaaatatta aaatgataca tcatgatata
      481 tcaaaaaaat acactaatga tactgattat aatgatactg attatattaa gactgagaat
      541 aatgatatgg atgatttgaa tgataagaaa tcaacatatc ctagtaatca tacaaatcat
      601 tcaaatcacg acaattcaaa ctttaataat gaggctttaa aattccaatt actcgaagaa
      661 ctaccacaga gtattcaaaa ctatctaagt aactttgaag tagctgaaat taaacttatt
      721 aaatctgtgt tattaaaagc caaaacatcc ttcaacaatt ctattgatgc atattattta
      781 ttagaagata tggaatttga aattgttagt gttcttaagc gttttaaagc tacattaatt
      841 caaaaaaatg aaaccgttga agcaatgcaa gggtacttaa tgaaatctct taaatctgaa
      901 tttgcagaag tacatacgct taataaacga cgtgatcatt taccaatcac ttctttattt
      961 aatcaataat acaacttaat aagccaacaa tgatccaatt agagaatatc tttaaataga
     1021 tattctctta actgtaggcg aactttattt tcaatgaaat gtaattaatt aagtaagtgg
     1081 gactaaaatt gaaacgttta gtcccatttt tataaacaat taatattcat tgttactact
     1141 atcagcaatt ttttcttttt agtggaatcc aagtatttgt aagcatgata aattacttct
     1201 ttttaaattt atttggctta ttcgtattaa tgtatttgga atacatcttt aacaattctt
     1261 ctgtttcatc tggacttaaa tgttcacatt caaaatattt ttcaagcatt gcaccttttc
     1321 gaataagtct atgcgctctt tctttgcgat ctaaattttt taatctatgt tttcttaatt
     1381 cagctttttc aattgcagca tttgtttttt tgagattttg aaaatcattc atcttatcac
     1441 ttactattct gattaatttc gttttctttt aaattttcat tgttcccgtt gctgttattt
     1501 tgttcgatat ctttattaaa ttcttcaatg actttatcca taattttata caattcatca
     1561 ttagagttaa tcatatttaa attaagtttt tttaaaaaat aaccaccaat tttattagat
     1621 agttgtgctt cttgttgttt cttttgttct ttcagttgtt caatttgttg ttctaattga
     1681 cttaactttg aaatatcggt ttgtttgatt ttagacatta aaaaactccc ttagtttatc
     1741 tatataaagc ataccataat tcattgggta agtcgtacat tcatggtata atgtaaccag
     1801 ttcttaagac actgcccatt tacatgcaaa ttagaaattg gcataaaaat gggcaaccat
     1861 actggttgat cgttatagtt cccacagggg tttaaattca aaaaagcgag gaggtaaaat
     1921 catggaaaaa ggttacttta tgttgagagt gactaacatt aatcgagcaa caaaaaatat
     1981 tgttgcatca gcgtcgtatc gttctgatga agcattatat agtgaacgta cagatgaaaa
     2041 aattaagttt agaaatcata ctgttaaacc tgaaagcatg attttaacgc ctcaaaatgc
     2101 acctgaatgg actaaagata gacagcgttt gtggaatgaa gttgataaag ttgaaaagca
     2161 taatgcgaaa acaaataacc ctagattagc aaaagaaatc ttgttaagtt tacctaatga
     2221 ttttgataga gaagtacaaa ctgaattaac aaaagatttt ataaaaagtg agtttgtaga
     2281 caaaggaatg gttgctgata tttcgattca tagagatgat atgaacaacc cacacgccca
     2341 tgttttactt actcaaagac cttttaattc agatggtact tgggggaaaa agacaaaaac
     2401 gagaacgcaa tatgatgaaa atggcaatgc gattttaaat aaaaatggta ataaagttag
     2461 aaaacaagaa cgctttgccg actttgattt caaagaagtt cgtaagcatt gggaattaaa
     2521 attaaatcaa tactcagaac gtgaacaaag tttaagacga tatgatagtc gttcttttga
     2581 agcgcaaggt ttagaaaaaa tcgcagaaat tccacttaca agagaagaat atagattaga
     2641 acaaaacgaa aaaaaacgct gtgaaaaaga gggtatcgag taccaacctg ttacttatta
     2701 tggacagaaa aatgaacaaa ttagaagata taatcgtggc gaagtatcac aattatttag
     2761 tgataaagag aaagaacaag cacaaaatga aattagatta tttattcaaa atgctaacaa
     2821 tcaagtaagc gaaaatgaac aaagttattc tattttattt gatagatata aacatgatgt
     2881 tggctattca gaggcaaaag aaactattaa aaacacgttt gatagtgcgt ctacttttgg
     2941 tcgtaaaatt caaaatgact tactcaaaaa tgaaattaag agaagtcact taaaatttta
     3001 tgcagataat tatgatacta attatcaatt tagaagagaa gttgaaaata aaggatatag
     3061 tcaacaagag tttattaata ctgttaaatc taactttaaa gaattactca atgaaaagaa
     3121 taagttagaa agcagagaag aaaaacgtaa agaaatttat caatcagcta aagacgttta
     3181 ccttactgaa attgataaaa acaacctaat tgttcagcaa atgtacccta aatctcataa
     3241 tcaatttagt aatgatgaga aagcatttat tgttgatgag gcacaaaaag gtaatattat
     3301 aaaagcatct aatgttcaat atctattcaa acaaaacaac tatatacctt cgaatgtatt
     3361 tctagaagat acctataaaa aagcgagtaa ggatattttc tttagtgaaa gacagcttaa
     3421 aaacttagaa aaagatagct ttgaatataa tgttgagttg caattcatta aagaaaaaga
     3481 aaaagaaatt gatagttaca aagaacatat tgatgatgat ttaagaatag atataggcga
     3541 taaaaacttt gaaaaagtca aagaccaaac acctaatgag aaagttcaat tacttattaa
     3601 acttgagaaa tataacaatg tcgatcaaaa agaagttatc gaaaaacata ttaatcgaat
     3661 agatataaat gataatgaca atcatattga acatgaaaat gaacaatcta atcatattaa
     3721 tttaccaact ataaacgcta gtgacttcct tatgtattat gcgaatgaaa ctgaaaaaca
     3781 aaacaatatt aatcataata aaaagaagaa gaaacaagag agaaataatc aaatgagaag
     3841 atagtaggca attgaaatta taaaaagttc attctttatt aataagaaac ttaaacaatt
     3901 gtggtacatt ggtcttaccc ttattactac atgaggcgtt ctgaaatgaa catgcccgaa
     3961 tgaatatgga gcaaatgcaa caaatgatga tggaacaaca aattaaacaa aaactaggct
     4021 acttatcccc tgtaaaatac agagaattag cagcctagaa catagtgttt ttattaagtt
     4081 cccattttaa gggttcagtg ccttgtagtt attgtgtttt tatatacttt actacttatt
     4141 ttcgttgtta tcatcaaagg actgcatgaa gttcgtgcat tcattcatca tattatccat
     4201 tctctggtca taatcagaac cttgggtaaa accagtttgt ccaatgacga ttaaaccagc
     4261 tagtacaaac gacagcacta aaggtaactt ctttttcatc gcttatttcc cctttcattc
     4321 aaagtatcct aatccttttt taacactttc tttaattttt catattcatc ttcattaatt
     4381 tcaccttggg caagtctttc ctttaaaatt tgtaaagaat catctgatct tacacctttt
     4441 ggtttttctg aagcttttgc aattaatata tatacaccat aaaataacaa gccaagaatg
     4501 ataatccaaa aaatcatgcc aatgaacccc attccgccca tcatatgacc catacccata
     4561 caatttgtca gtcctttcct tctttcttgt tttacaatta taccataggg gggtataagt
     4621 atcccaaaaa agtgttttta atattagtag cagaaggcaa ttcattgtaa tgatctatta
     4681 agtcgaccat tcgacaagtt ttgggattgt taagggttcc gaggctcaac gtcaataaag
     4741 caattggaat aaagcaccta tgattattta aaaaaataag ttataataca ttcaaaaata
     4801 tttttgaatg agttgtaatt atgattcaga ctattgtaac tgctgctatt ctttatattg
     4861 tgacagcatt agacttatta gtgattttat taatgttctt tgctagagca aagactagga
     4921 aagaatatcg agatatttat attggtcaat atgtaggatc tgtgacattg attgtcataa
     4981 gtttattctt tgcctttgtc ttaaattatg ttcctgaaaa atggatatta ggattattag
     5041 ggttaatacc gatttattta ggaattaaag tggctattta tggtgatagt gacggagaag
     5101 agagagctaa aaaagaattg aatgaaaaag gattgtctaa attagttggt acaattgcaa
     5161 ttgttacgat agcaagttgt ggcgctgata atattggtgt atttgttccc tattttgtga
     5221 cattaagtgt tactaattta ttaattactt tgtttgtctt tttaatttta attttcgtct
     5281 tggtatttac tgcacaaaaa ttagctaata ttccaggagt tggagaaatt gttgagaaat
     5341 ttggtcgttg gattatggct gttatttata tagctttagg tttatttatc attatagaaa
     5401 atgacactat tcaaacaatt ttaggattta tattttaatt tagggtgtga ttttatatga
     5461 gctataaaaa tgcttgtgat gtgatctgtg tacatgagga taaagttaac aatgccttaa
     5521 gttttttaga agatgataaa tctaagaaat tacttaacat tttagaaaag atttgtgatg
     5581 agaagaaatt gaaaattata ttatctttga ttaaagaaga tgagttgtgt gtttgtgata
     5641 tttctttgat attgaaaatg agtgttgctt caacttcaca tcatttaaga cttttatata
     5701 aaaatgatgt acttgatttt tataaaaagg gaaagatggc atattatttt attaaagacg
     5761 atgaaataag agagtttttc tctaaaaatc agaagggttt ttgaaatgag tgaaacgagt
     5821 ttcttcttgt cttgatacta taaaaataag caaagatata acataaaatg acttatcgga
     5881 agttatctgt aactcaatta ttagaaatga tataatacaa aagtcgtcgt tcacttctgt
     5941 gctgtattta gcatggaagg aggtgacatc atgttcagta cactatttgt aactattata
     6001 gctcctatca tagtaggagt tatactcacg ttattttctc attggctgaa taatcgtgaa
     6061 aagtaattta gcgacgacat atagctaata caccaaaaga gcccgataac tattcgcagt
     6121 agttatcggg ctcggtgttt atcatgttag tacactattt gttaatcaaa ttataacact
     6181 ggttagtaga ggaatgcaaa attgaaatta cggaatataa aggagataga atctgaaaat
     6241 gagtattgtt acaaacgaaa acgaagaagc agttattgct atattaaaat tcgtacatcc
     6301 aaattacgca gaagactttg aaaatgacaa tttatacttc aataatcttc agagatttca
     6361 tgagattgaa cataatgaaa taggggataa attagaagga gttatttcaa acaaactagg
     6421 aaataaatat gcgcctaatg atgaagtaga gatgtatatt agaaatttag aagttcctaa
     6481 ttccaaaatt cacaaagtaa atgtaaaaga agtaactttg aaaaatactt cagatatcgt
     6541 taaagagttt aagatctgct gtttctcaat aataaggatg aaagatttag tagagtgtga
     6601 tgatggtaag tataggttaa atcaagaatt tgtacgaaaa atgaatggta taattgataa
     6661 tagaaatata tatgtaacta ttcatttaaa agatttcata aataaattgg ttaaaacatt
     6721 ttcggagaag gatacatatt ttaaagcagg cattgttgaa tatttcgaag ataaacaccc
     6781 tctattctat aaaatagaaa gtggcaaaaa acttatagtt aaagacttta taaatgctag
     6841 tttttataaa actagtcaat atgatagtca aaaggaatac agaattctaa catataaact
     6901 aaaagaaaat aagcttaaaa tcgaagggtt gtacgacaaa tttcagaaat tagaaaattt
     6961 aaaacaactt gcaattaatt tttatacaga agaagaatat agaaatttaa ataaatgaca
     7021 aatttaagta caccataatc atacaaaata agttattgaa tttatagtaa cttgtcactt
     7081 tattcaatat atgagaatga ctttacctaa tcaatgagaa aagcaacgca ctatattaaa
     7141 atgcgttgct ttttctatta tcgaatacct ataactaaac tatctctaac tgtttctata
     7201 acttctgtac ttattttatc taaaccattt atatccataa tttaatttct ttttggaggc
     7261 cacacaaaat atgaaataca aataattaag tctataataa taacaattgt ccaaatatgg
     7321 ataacaccat ccatagcttc tgtacgactt ttatcattaa tcaaataaac aactaaatgt
     7381 aaaatcccag tacctataat gtaagacagt aaatgtttca accaactttt agcatagttt
     7441 ttagagtaat ctaaaccgtc aagtttataa ggtttggaac cttgcttcat cacataatat
     7501 ctaaatctat catctgccca atttatcatg cttttgccaa agacaagaga aattgaaata
     7561 taaactgctg ctatagcatg tggcatttca gctgttgcac cattcataag gtctacaacc
     7621 gttgttataa taagtattaa atctataata ggcgtaagtg caagaaagaa taaacccaat
     7681 gtttgttgat ttaagatata tcttgttact aaaccaagta atattacaaa ccaaaaggct
     7741 atttcacaaa aaattataag ccatgctata aagttcacgg gccgtcctcc tttattgcgt
     7801 taatctaact atttcttcat ctacaatgat ttgaatatca tcgtttgaaa caccgtttgg
     7861 attaagcaat ttatgtaaag ctaaaccgtc aattaatgca tgtaatttca tcgaattaag
     7921 atgaatattc acattgttct tcaacaaatg atcgtttttt aataatgtca aaatactatt
     7981 acataattgg tctaacccat catcaagtgt actttgaccg tactcatgta tgtcattgcg
     8041 aaacgccatc caaacttcca tatcagctag tctctcttta tccaatggta gtactgttaa
     8101 taaactcgct tttgctttat ctattgtagt aaggttttca gatttaaata ttgcttcaat
     8161 tctcctcctt acttttaatt ctactgtaga cattacagca tttaataact ctgaatgatt
     8221 cggaaaataa tatctaatct gtccaggtgt catatcagct aatttcgcaa tttgtcttac
     8281 agtagatccc ttaactcctt tttctacaat ggagtcgaaa gcgtattgaa tgatttgttt
     8341 tttcttttct ttatgattaa ttatttttgg catacctata tgttaacaca ttttaataca
     8401 ctcgtattaa aaaagtgtac agaatacaac cattttctgt acactcgttt tttatgtcta
     8461 aataagtatg tattacatag aattatgtgt tcaaaaaccc aacaaaaaat ctatgttcac
     8521 aaaagacctt gtgattaagt tatggtacac tgaaggtgta tataggaggt ttgtattttg
     8581 aaaataggtt atgcaagagt ttcaactgga ttacaaaatt taaatttaca ggaagatcga
     8641 ttaaatacac atggttgtga aaagatattt aatgaccata tgagtggttc aaaaagtaaa
     8701 agacctggtt tagataaagc aattgaattt gcgaggtcag gagataccat tgttgtttgg
     8761 agactagata gactaggacg taacatggag gatttaatca cattagttaa tgaacttaac
     8821 gaacgaggcg tgagttttca tagtttagaa gaaaatataa cgatggataa atcaagttct
     8881 acaggacaat tattatttca tttattcgca gcatttgcag aatttgaacg taatttaatt
     8941 ttagaacgtt cttcagctgg ccgaattgcg gcacgtgcaa gaggaagata tggagggagg
     9001 cctgaaaaat taaataaaca agatttgaat ttacttaaga cgctttatga taatggcaca
     9061 cccattaaaa caatagcaga acaatggcaa gtttcacgta caactattta tcgttacctc
     9121 aataaattgg aggacaagga agatgaaaaa caaggagaag tatctaacta atttttctga
     9181 agccaaacgt aaagaagcta ctcaaaagta caatataata aaacctttta tcttgggaaa
     9241 tcaatcttta tcaagtattt ctaaaaataa ggacattgca ttaagtacac tttataggtg
     9301 gaataaatta tataaggaag aagggcttac tggtctaatt cataatacaa gagttgataa
     9361 aggtgatcat aaattagaac aaaacataat tgacgagatt aaacgccttt cactcaagaa
     9421 taaaagaaat agtattgcta caattcatag gaaaatcgtt aattattgta tagaaaataa
     9481 ttttgataaa ccaagctaca aacaagttta tagtattatt aaagcaatgc ctaagtctgt
     9541 tattgatttc tctcaccaag gtgaaaaata ctatcaaaat aagtacgatt taatacaaat
     9601 aagagaatcc tcaagaccca atgaaatatg gcaagccgac catactttgc tagatattta
     9661 tatattagat caaacaggta atattaatag accctggcta accattatta tggatgacta
     9721 tagtcgcgca attgcaggat actttataag ttttgaagct cctaatgctc aaaatacagc
     9781 attaacacta caccaagcaa tatggaataa gaataatacc aattggccag tatgtggtat
     9841 acccgaaaaa ttctacacag atcacgggag tgactttacc tcgcatcaca tggaacaagt
     9901 cgctattgat ttgaaaatta acttgatgtt ttcaaaagtt ggtgtccctc gtggtcgcgg
     9961 gaaaatagaa cgtttttttc agacagttaa ccaaactttc ttagagcaac ttcctggata
    10021 tataaacaat aatgatactc ctagcgattt aatagatttt caaaatttcg aagaaaaatt
    10081 acgatacttt ttaattgaag attataatca aaaagagcat agtgttatcc agagcactcc
    10141 tatcaatcgg tggaacagtc atcatttttt ccctaatatg ccaagcagtt tagaacaact
    10201 tgatttatta ttattagaaa tacctaaatc tagaaaaatt cattcagatg gcattcattt
    10261 tcaaggcttt agatacagta atacaaacct agctgcttat gtaggtgagt atgtattaat
    10321 tcgttacaat cccaatgata tggctgaaat acgtgttttt tatagagatg aatttctttg
    10381 tacagcaata tctcctgatt tagctgatta ttcaattgat ataaaagata tacaacacgc
    10441 acgtagtcag agaagaaaac acttaaaaca aaatattgct agtccaagca ccactgattt
    10501 aattaaggaa gaaaaaaatt atggttattc acctcaagaa acgactaaaa acgtcaaaaa
    10561 attaaagagg tatcgtaatg actaaacatc agaatttcat tgaaacgaaa gagtataaac
    10621 gatttgctga attttgcgat gcttgtatca aatatcaata tattgggatc tgctatggtc
    10681 aacctggtgt cggaaaaact ttatcttcta ggtattacac aaattggaat actattgaaa
    10741 agcaagttaa tcatagaggg tgggaagatc tagctagtaa aacgactgat gatatattat
    10801 cggtgaataa gatattttat actgcaccgg ctgaaaaaca aacaagatta agtaatgatc
    10861 tatatagtat tagtgcaagt attgatttgg gtcaaaaatt acacatcgta aataagtatg
    10921 gtcatgatca tagtaaacat tatagtgata tgtttaaata tattgattta attatagtag
    10981 atgagattga tcgccttaaa gtgcaacatt tagagcaatt aagagctatt tatgatgaac
    11041 ataatttagc aatgatattt attggtatgc caggtataga gaaaaaacta tctcgttatc
    11101 ctcaactata ttcgcgtata ggttttgcac atgaatttga taatctaagt aaagacgaga
    11161 cgcatcatat attagaatat aagtggcaag atttaggatt tgatttaaaa ctcgaagact
    11221 ttactgatta tgaggcaata acgacgatta ttaaaattac aaaagggaat tttaggctga
    11281 ttcatcgttt atttgcgcag atagatagaa ttatggatat aaatggctta gataaaatca
    11341 gtacagaagt tgtagaaaca gctagagata gtttagtcat aggtattcgt taatagaaaa
    11401 agcaatgtac tttaatatag gacattgctt ttctcattta ctaggtaaaa tcattctcat
    11461 atatcaagta aagtaacaag ttgttgaatt tatagtaact caaacgtatg attagggtgt
    11521 atattaatta tagagtgaag atgaatgatt ataggttatg caagagtatc ttcgatagat
    11581 cagaatctag agagacagct agataatttg aaaacatttg gcgtagagaa aatatttaca
    11641 gagaaacaat cggggaagtc agtagaaaat agacccgtat ttcaagaagc acttaacttt
    11701 gtgagaatgg gcgatagatt tgtagtagaa tcgattgatc gtttaggtcg taattatgat
    11761 gaagtgatta acacagttaa ctatttaaaa gataaagaag ttcaattgat gattactagt
    11821 ttacctatga tgaatgaagt cattggcaat cctttattag ataagtttat gaaagatcta
    11881 atcattcaaa tattagcaat ggtttcagaa caagaacgaa atgaaaataa acgtagacaa
    11941 gcgcaaggta ttcaagttgc gaaagaaaaa ggtgtatata aagggcatcc gttactttat
    12001 tcaacgaatg ctaaagatcc tcaaaaacgt attatttatc atcgagttgt agaaatgtta
    12061 gaagaaggtc aagcaatcag taaaattgca aaagaagtaa atataacaag acagactgtt
    12121 tatagaatta aacatgataa gggattatct tgataaatag gttgtcaatg caaatgagcg
    12181 tttctcacag cgtaccaaaa ctcataatat attattgaat tgagatttta ataattgtac
    12241 aagaaaaaag agtacgaatt cgcactcttt ttctaaacta agtattttac tattgttcct
    12301 tttgcttatt tatcataact tgaatgtata aagtaatcca aagttcgtga ggatatggta
    12361 tttgggtatc atttgcttca attactatat tgtgtttttc tcctctacgt cgagttacta
    12421 gatttttacc taaatcaaaa aatgaacgtt gcgctgttaa tatttcatta ttttcttttc
    12481 ctgttatcac tgttttagtt gaaaaataag ggttactaaa cttatatgtg tcgttactgc
    12541 ttgaaaaaat atagggcgtt tgttgcttta ttcccccttt taacaacctt atcatctgta
    12601 acattcctac ttcttcttca tcaataaaga ctctataatg gggccttaag gaccatagtt
    12661 tagttctctt taaaataata gtgtgatcta ctgatgtaag tttaacacca tagacaggga
    12721 aaatatcaaa tacacttagc catttttgaa gattattatt aaaatatgga gtccatattg
    12781 tatcactcat accatgaact ttgatatgta taccatcgaa tatgtacaat ggggcttgat
    12841 aaaaatattc cttctcatat aagttaggac tgttttcata tattgtgagt tcttttttat
    12901 attttccttt agagtaacgt cttatcataa tagttcccaa taaaataaca atgcttgcta
    12961 cccaaaaaat aacgaatatc catggagaaa tagagttatt aaaaaccccc atcatacttc
    13021 caatcatgaa tattgttact aaaattgttt caataaataa aactaaaaca ggcaatttta
    13081 taactccttt taaaatagta aatattttac taaatgcaat ataacatagt aagtttttaa
    13141 acacattgat atgtaaaaag tatttgacat ttatgaggtg ttataatgaa tttaattcct
    13201 tttattatta ttttaatttt ttcttgttta tggacggcta taacaaacaa atatttaccg
    13261 tcagaaacat tagatacaaa aggacaccaa gattgatacg atgaaagaca gcgtaaaatg
    13321 tttattgaaa tactggctaa aagttttatt tggattatct attgtatgtt atttacatta
    13381 ttgcttagat tgattggttt aacaccaaat cttgaaaaaa cttggttttc tcaatatcca
    13441 gaaattttct ttataatagc tgctatatta cttatggctt ttaattactt tactacaaat
    13501 aaaaaataca catctaaagg ttaaattaat gaaaaataga attagagaat atagaaagca
    13561 aaaaagaatt tctcaagaag ctttaagtaa ggaattaaaa gtatctaggc aaactattaa
    13621 tgctatagaa aacaataaat atgatcctac attaacatta gcattcaagt tggcaaaatt
    13681 gtttgataca actgtagatg aactattttc ttaaacattc atttatcaca aaaagagagt
    13741 gccaattcgc actctctttt tgtgtagtaa tattatttaa attttgtctc aataaagaac
    13801 aaatctaaca caaaatttat gttaatattt taataaaata ttattttttt ctttctttct
    13861 ttttgtctct tttttctttt aatttcgcta aatatttcga agtctcatct gtaaaagtag
    13921 atacaattgc aacgattata tctatgattt taattaaaat ttccatcgat tagtgcctcc
    13981 ttttaaattt tatatgctat ctccttttat aggtgacctt ccgttagaaa atttaatttt
    14041 taaagaaaca cattcgtcta ttttagatgt gttcataact tgaaaatgta aatgtggctc
    14101 ggaggagttt ccagaatttc cacatttacc aatcaaatct ccttggcgta ttttttcacc
    14161 gattacaacg tttatactag aatattctaa tcgttgcaaa atcaaaatat gtctcaataa
    14221 tgatcctgtt gatgattaat acaaaacata actttaccac ttttttaaaa agtcgataga
    14281 gttatcttga aattcacttt aaatctttgc ttatcatttt atctaattct ttttgttctt
    14341 tctttttatt atctttttga gccctactcc actgacctaa taagaataat aaacctatta
    14401 cacccaaaat aagagttccc caaatattta atcctaattt acccgttgta tataaaaata
    14461 ctaatgctac tataaataat ataggtacaa ttccacctat tatcttattt cctgtcttag
    14521 ataaaaaata ctgtatggca tataaaatag ctggtgcaaa tgttaataaa ttactcaaat
    14581 tcactcaatc tccttttcat gactatatat ttctaataat tgtttagcgt cattcaaatc
    14641 taatttttcc tcgatagcca gcttttttac ataattaact aatgaactct cttcattgtc
    14701 ttttgcagat tctatccttt ctatcacact atttaatcta tttcgaacag ttggatatga
    14761 cacttcataa tatttagcta atgcttttag tgatccagaa ttaacaacaa aatttttaat
    14821 aaattcaaaa tcttcttttt ctaagttcat catccattta ggaatatcat tatttttcaa
    14881 tatattcact ccttgaatat aaattatcat ataattaaac attattaaaa ttaaatttaa
    14941 cattattgaa tttttgatta acttatatta tttaactttc attattgtta aataactttc
    15001 tgaaaaatat gtctgattag catgactaat gtttatcaga aagcatgtta aaagagactt
    15061 cttatttcaa caaggagtct tttaatagtt ttataatcaa actttgtctt aataaagaaa
    15121 atatgtgcac atttatttct ttattgcttc aactaatata aatggaggga actgttttaa
    15181 cgtattaata cgaacttcat cataatattt aaatacttct tctgattgtc caaggtcctt
    15241 aacacattca atttcaaagc cgctatttat taaactattg aaaatagttt caatagttta
    15301 atggtatttg aaaacgtctt ttcctatcca attagcagaa cgaatagatt catcaaagta
    15361 acgttccatt cgcaaataaa ctccattttt atcttctttt ttaacctctg aatccatagt
    15421 agctgtttgg attggatgct ccatagtaaa tactagggtt ccttcacttt ttagtaattg
    15481 gtataatctt tgacaaccta gtttttatga atctttaaga tttataaaat acggagaatt
    15541 taaagtgtct gaggaactta aattttttaa atatgttaat caatttaata ttaagtaata
    15601 aagatgcagc aaataaatat tatttacata atcgatgatt atcagaagtt tgagtcacat
    15661 taaaaaggca caacaagttc atgaacttgt tgtgcctttt taattgcaat tagttaccaa
    15721 ataaacgact ccaaaatccc tttttaggtg gttctacctc cctattatca tcaggatcat
    15781 tcttcgtttc ttcaacgaac ttatcctcat ttgttagttc atcttcgttt atactgtcat
    15841 cctttttttc tttagctata ttcttatgat ttacttcggt tggttggctt ttcttttgtt
    15901 gttggttcgc attttgaggt tctttagtaa aagttgcttc tttcggatta atattttgtc
    15961 tattattcgt cgctgtatca aaagaataat taagctgtct ttcttcttct aattggcttt
    16021 ctagtttttg aattttttta ttgctttcta atgctaagac ttgctgattt tctaaaagtc
    16081 tattaagtgt atttatttgt tctttatctc tatttgcctg ttccttatat atatctagct
    16141 gaatatataa ctgctttatt gtttcatctt ttacctgatt attatcgtta tcagaatttt
    16201 tttcatttat tttactttca gcatcaatgc tctttttctg atttttttta attctattta
    16261 ctactacaat ctcatcttca ctagataagt aatttacgtt atcaattttt tgaaatttta
    16321 catttgcttt tttagcatta ttataaactg tcatttttgt cacatttagt tcgtcagcga
    16381 ttttcttcat acttttcata tagtagcctc cgtataacta tatatatatg atatttatta
    16441 tgattatata gttattatac ttaccatatc aatactttta tacttataca taaaatatat
    16501 acatataatt atatgtatat atttcaccct ctttatacgc ttcttatata ccttttatac
    16561 gtattgcaat agctttcttt atataacatt ccatatcact atataaaaac aaaatataac
    16621 cttttatcat tcttacatga tatatataca ctaaatatat ataaaaaatg taacaaagat
    16681 tgggaaaatg ttattataaa tagaaagaag cctaactacg ggaatagtta ggcctcgatg
    16741 gtaataaaaa agttgttttt gtacagttgt tgtattcata ttatatatat taagaattat
    16801 tagcgcaagt ctaatacata tatacttact tatgactttt tattacctct tttaaaattt
    16861 aaatatgaaa gaggtttttt gt
//
