LOCUS       NZ_CP024462            33858 bp    DNA     circular CON 25-NOV-2023
DEFINITION  Klebsiella pneumoniae strain QS17-0161 plasmid pMR0617mcr1, complete
            sequence.
ACCESSION   NZ_CP024462
VERSION     NZ_CP024462.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN07792166
            Assembly: GCF_002752955.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 33858)
  AUTHORS   Snesrud,E.
  TITLE     Sequencing of mcr-1 carrying Klebsiella pneumoniae from Thailand
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 33858)
  AUTHORS   Snesrud,E.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2017) Multidrug Resistant Organism Repository and
            Surveillance Network, Walter Reed Army Institute of Research, 503
            Robert Grant Ave., Silver Spring, MD 20910, United States of America
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200.0x
            Sequencing Technology             :: PacBio; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/25/2023 03:00:45
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,574
            CDSs (total)                      :: 5,451
            Genes (coding)                    :: 5,315
            CDSs (with protein)               :: 5,315
            Genes (RNA)                       :: 123
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 88
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 65 of 136
            Pseudo Genes (incomplete)         :: 78 of 136
            Pseudo Genes (internal stop)      :: 37 of 136
            Pseudo Genes (multiple problems)  :: 33 of 136
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP024462.1.
            Bacteria and source DNA available from The Multidrug Resistant
            Organism Repository and Surveillance Network (MRSN).
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..33858
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="QS17-0161"
                     /isolation_source="sputum"
                     /host="Homo sapiens"
                     /culture_collection="MRSN<USA>:480738"
                     /db_xref="taxon:573"
                     /plasmid="pMR0617mcr1"
                     /geo_loc_name="Thailand: Chonburi"
                     /lat_lon="12.6890 N 100.9820 E"
                     /collection_date="2017-05"
                     /collected_by="AFRIMS"
     gene            1402..1917
                     /locus_tag="CR231_RS29065"
     CDS             1402..1917
                     /locus_tag="CR231_RS29065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025391.1"
                     /GO_process="GO:0006457 - protein folding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="J domain-containing protein"
                     /protein_id="WP_001025395.1"
                     /translation="MNIQEALNVFGLSGELTEKDIKAAYRKAALKYHPDRNPLGAELMK
                     AVNAAFDVLMANIDKINQFQSTDEHARYNYGDDLEKVLNVLSGLSGLVFEVIGNWVWIS
                     GETITHKETLKEIGCKWAAKKKQWFYRPDEHKSYWNREEHTIEEIRAKYGTTGQRRATG
                     WQRVETRA"
                     /name="J domain-containing protein"
     gene            2022..2564
                     /locus_tag="CR231_RS28515"
                     /old_locus_tag="CR231_28360"
     CDS             2022..2564
                     /locus_tag="CR231_RS28515"
                     /old_locus_tag="CR231_28360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001401654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001083906.1"
                     /translation="MNSFFEQYHPVFEVVCRILGNGWRVNKLDDCSSRIKLTSPQFKNY
                     SVHIRMEKDRFSVVGSVDSRSWRSPHHVCTLSRKRNPVDIAADIERKILVNASQEVLQA
                     IEYEKHQVEKKDEILILKGMLSQLVQLESWYGALTGFKAENGLNGKVTEQGDSYDLQIR
                     GLSIDQLVKITGYLKQL"
                     /name="hypothetical protein"
     gene            2561..2812
                     /locus_tag="CR231_RS28520"
                     /old_locus_tag="CR231_28365"
     CDS             2561..2812
                     /locus_tag="CR231_RS28520"
                     /old_locus_tag="CR231_28365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001565860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001230707.1"
                     /translation="MRKNKGDVTYFLEKEGDNYRLTKRIKARTNVKIGNKTTKITLYDA
                     VLNENELQHIDFTCAGLREDDETPVKNLIKEFMLNETR"
                     /name="hypothetical protein"
     gene            2799..3026
                     /locus_tag="CR231_RS28525"
                     /old_locus_tag="CR231_28370"
     CDS             2799..3026
                     /locus_tag="CR231_RS28525"
                     /old_locus_tag="CR231_28370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000801440.1"
                     /translation="MKPDNTPENVKKLRLKAGLTQKECSHIYGVGLRTWQKKEEVNTQN
                     SQSLSLVEFEFLLLLAGEHPEYVLCKRESK"
                     /name="hypothetical protein"
     gene            3480..3779
                     /locus_tag="CR231_RS28535"
                     /old_locus_tag="CR231_28380"
     CDS             3480..3779
                     /locus_tag="CR231_RS28535"
                     /old_locus_tag="CR231_28380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000650309.1"
                     /translation="MKCSSVFTSTTNHVFTFERVTLCTIILMHKDTGQQYVVIFTDNNK
                     IRDYKAGIVPQFGELKQSDVDLVLFYRDEYEKYFDSLKDGDECLSFKDFIECLC"
                     /name="hypothetical protein"
     gene            3870..4220
                     /locus_tag="CR231_RS28540"
                     /old_locus_tag="CR231_28385"
     CDS             3870..4220
                     /locus_tag="CR231_RS28540"
                     /old_locus_tag="CR231_28385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000854261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000854259.1"
                     /translation="MKTLKQAAMQFASDLRNNRCFKAAYNDALLELDREDLNAIVQCTF
                     LFEPKRTLAELDKLIKKIEVEEDYEFCVSLDKGKGLHEVRTFKSEREALDAYRILTLYG
                     YTVTIEKKEGND"
                     /name="hypothetical protein"
     gene            4525..4773
                     /locus_tag="CR231_RS28545"
                     /old_locus_tag="CR231_28390"
     CDS             4525..4773
                     /locus_tag="CR231_RS28545"
                     /old_locus_tag="CR231_28390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005653200.1"
                     /GO_function="GO:0003729 - mRNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family toxin"
                     /protein_id="WP_000520549.1"
                     /translation="MGKTDKLLAKFLNSKKTFEWDELVVLFSSLGYVKKEMQGSRVRFF
                     NAEINHTILMHRPHPESYIKGGTLKAIKQNLKEAGLL"
                     /name="type II toxin-antitoxin system HicA family toxin"
     gene            4770..5117
                     /locus_tag="CR231_RS28550"
                     /old_locus_tag="CR231_28395"
     CDS             4770..5117
                     /locus_tag="CR231_RS28550"
                     /old_locus_tag="CR231_28395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="WP_000681613.1"
                     /translation="MKHLKYKGYLGTVEPDFENNVLYGKLAFIRDLVTYEASTLAELEQ
                     EFKTSVDLYLQSCVEDGKEPDTPFKGVFNVRLDPELHRRVAEMAMEEDLSLNAFVNKAL
                     EKEVSNHRAGA"
                     /name="type II toxin-antitoxin system HicB family
                     antitoxin"
     gene            5478..5981
                     /gene="taxA"
                     /locus_tag="CR231_RS28560"
                     /old_locus_tag="CR231_28405"
     CDS             5478..5981
                     /gene="taxA"
                     /locus_tag="CR231_RS28560"
                     /old_locus_tag="CR231_28405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000781813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxosome-coupling protein TaxA"
                     /protein_id="WP_000781813.1"
                     /translation="MKMIAFRLSDDELKFAEHNAILSGFTSINAFAKHNVLNIETKPVN
                     IPVNNEPAKLVSVRLYPHEIELVKRNAALHGMSMSREIAIRVRQSLLKSEVCLYPDEVK
                     ELKKLSTAVDRVGRNIHFIIKGERFCTVNDPDFRKDVIEVIELCKQIDSKLETLTKSVV
                     NRFG"
                     /name="taxA"
     gene            5985..7214
                     /gene="taxC"
                     /locus_tag="CR231_RS28565"
                     /old_locus_tag="CR231_28410"
     CDS             5985..7214
                     /gene="taxC"
                     /locus_tag="CR231_RS28565"
                     /old_locus_tag="CR231_28410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001329504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA relaxase/nickase TaxC"
                     /protein_id="WP_001329504.1"
                     /translation="MGVYVEQEYRIKRAKGTGRDPKSPKLSGRHIHASKSAFNHKVRHG
                     ADKKAYTWTPTKEVTFKITGSGKTAAGIKNGIDYITRNGELEAYCYDGKGSEQTGKGED
                     FNREFTSTLSKGNDYSRTYRGENIDHVKNMVFSPPPEAGVSREDALKATVEFLKETYPN
                     HAFVAVYHDDKEDHPHVHVNIKLRDEETGRRLRLTKSETRKFRNGFHRKLKGMGYDVTA
                     TWKKDPERKREIERLQAENPKRLRNVYKVVDFGETSYQNKAGEKRTPFLTYETLKGGKQ
                     VTIWGKDLKNHFESEKLQPGTLIKVKKLAPTLVRSPMFNDDGTVAGYRETHRNNWQIEN
                     IALERNRERQVHERETRQPEESDVKKQLSRKHEQGHNIGFALEHGFTKDSEEHKKLRIQ
                     QERNWKGLGF"
                     /name="taxC"
     gene            7291..7584
                     /locus_tag="CR231_RS28570"
                     /old_locus_tag="CR231_28415"
     CDS             7291..7584
                     /locus_tag="CR231_RS28570"
                     /old_locus_tag="CR231_28415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134733.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]; GO:0016987 - sigma factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]; GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-like helix-turn-helix DNA-binding
                     protein"
                     /protein_id="WP_000134733.1"
                     /translation="MTEHDAICISALHQIFSDEEHLSEQQKDIILMYAYGYTLNEIADF
                     KGLKPSTVRKYLDSVRAELGGVSLAGIRTLVLIRTNALLVSSLSRISERGNL"
                     /name="sigma factor-like helix-turn-helix DNA-binding
                     protein"
     gene            7581..7796
                     /locus_tag="CR231_RS28575"
                     /old_locus_tag="CR231_28420"
     CDS             7581..7796
                     /locus_tag="CR231_RS28575"
                     /old_locus_tag="CR231_28420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EexN family lipoprotein"
                     /protein_id="WP_000760375.1"
                     /translation="MKKYLLFALPFFVVGCSEEVKSVDWWGQHLTEAKQKQAECEKSGS
                     DSQNCKNVKQALFIQSQKDAPVPTFD"
                     /name="EexN family lipoprotein"
     gene            8152..8772
                     /locus_tag="CR231_RS28580"
                     /old_locus_tag="CR231_28425"
     CDS             8152..8772
                     /locus_tag="CR231_RS28580"
                     /old_locus_tag="CR231_28425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012908959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing protein"
                     /protein_id="WP_000157549.1"
                     /translation="MASLFPALLLCAASVHPDTINDIARVESGFNPYAVAEIIPERERG
                     SYGKSVISHMPKSKEEALTVIREIENRKRRYSVGLMQITSSNFSFYSTSAEKLLDSCEN
                     LSVFEKIIVDCYKRGRSLENALSCYYTGNFSNGKRKEKEFNNTSYVERIGYTGNEKKYV
                     VPGTRSNGGEQRKNRSHNASVIWPETILKSAFVDNSHPTKVIN"
                     /name="lytic transglycosylase domain-containing protein"
     gene            8786..9112
                     /locus_tag="CR231_RS28585"
                     /old_locus_tag="CR231_28430"
     CDS             8786..9112
                     /locus_tag="CR231_RS28585"
                     /old_locus_tag="CR231_28430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbC/VirB2 family protein"
                     /protein_id="WP_000008647.1"
                     /translation="MSFKKSVCNRISSSVTAVMQRKNKVVMAVAGATVASPAFADGFSK
                     AETLLEKVKTGLSGLSLVTVTIACLWVGYKVLFGGSTIRECSPIIIGAIVIASAAEVAS
                     MMVN"
                     /name="TrbC/VirB2 family protein"
     gene            9131..11878
                     /locus_tag="CR231_RS28590"
                     /old_locus_tag="CR231_28435"
     CDS             9131..11878
                     /locus_tag="CR231_RS28590"
                     /old_locus_tag="CR231_28435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB4 family type IV secretion/conjugal transfer
                     ATPase"
                     /protein_id="WP_000105985.1"
                     /translation="MSTLYKAMTRPAMYVGVPVVPLTVVAGALFLAGVYISKLIWLAIP
                     VAVFVLRMITKQDDHIFNLYFLKLKMLGNSVCNRFFGARAFLSGQYEAVEIDEFVNAMK
                     LNERITTGKYIPYSSHVDKNIVKTKNGDYVATWQLMGINFESISAEMLETIDSQVATLV
                     RSFSGLPVSFYNHSCRASFYDAFTTKSGNKYADIISDCYYGSMKKNKFKGNTLYFTLIY
                     RPDGRVEKLEKRKKSIKEKKDDINIHVKRMNEMINTFSGALDKFTCKLLGMYEENGKVF
                     SSQLSFYNYLLTGKLQKIRVTDSPVYNVLGGVDVFFNHDTGQICRIDGNKFFRSIEIKD
                     FCSETASGVFDVLQYSDADYIITHSYTSMSKSEALSTIKRAEKQLKSTEDDAVTQLQEL
                     EKAKNDIVSGDISFGYYHFTLMVMADSIRELDESVSKITADFTDLGIIPALSTMSLPAA
                     YFAQLPAVFHLRPRLSPVSNVNFVELASFHNFYQGKRDKNCWTEAVAILKTPSKQAYYL
                     NLHNSVLFKDETGEKNLANTKVIGTAGSGKTMFLSYLACSLQKYNNPETFADSAKNKKL
                     TCVFLDKDRGAELCIRMLGGEYYTVKSGEPTGWNPFALEATKRNRIFVKQLMEILCTRN
                     GERLSTRERLLISESVDAVMDFPPGEMREYGITRMLEHLMQRDDRDEQENGIILRLSQW
                     ANGQAHGWVFDNAKDTFNIQHVNNFGIDGTEFLDDPMVCAPITFYLLYRITQLLDGRRL
                     VIFLDEFWKWLQDEAFSDFVYNKLKTIRKLNGLVIPATQSPDEILKNKISRAVVEVCST
                     SIYLANPDADYNDYVEGLKLTPEEFNIVKNLDPMSRQFLIKKSSLKKGDGKSFSALATL
                     DLSGLGGYLKILSASADNLEIFESIYHEGMEPDDWVPEYLERAI"
                     /name="VirB4 family type IV secretion/conjugal transfer
                     ATPase"
     gene            11890..12606
                     /locus_tag="CR231_RS28595"
                     /old_locus_tag="CR231_28440"
     CDS             11890..12606
                     /locus_tag="CR231_RS28595"
                     /old_locus_tag="CR231_28440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_000832283.1"
                     /translation="MKRVKTLMLISLLTASFYSSAGIPVAIDASPEWAVEAARWTERLK
                     QWSETAQHYQSQIQAYKDQLATATGIRNIAAFTNELSNLQSELTNIYKQGNSYISDFTS
                     NPEGALSSQAKNLFSKYGAFDMCNTGYERNDNLCKARIVSTAASIEQGNEINKQLSSAM
                     SQIQSLSSRIEASKDIKESQDLANALQAQSLKMQAIKMQYDVWNNKNKADHEMLVTQEQ
                     EAFIKQQKEAEPLTFD"
                     /name="type IV secretion system protein"
     gene            12618..13712
                     /locus_tag="CR231_RS28600"
                     /old_locus_tag="CR231_28445"
     CDS             12618..13712
                     /locus_tag="CR231_RS28600"
                     /old_locus_tag="CR231_28445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001677777.1"
                     /GO_process="GO:0030255 - protein secretion by the type IV
                     secretion system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_000046889.1"
                     /translation="MAQGFFVKYNSTVMDSVDKISSSYQTQFANDIMSLATVSVTLYVL
                     WKGYQILASKTQTPLQDLVWDLSKFAIIIMFITNADGYLTAATDALQGMKDGFSGGVSV
                     WQTLDNLWKSTQNLGAEIYSLDKSTYVKDQGVVGQFLIWTGSLILMAVSVVVFLTADVT
                     MKLLIITAPIFIFCLMFGFIRSMFNNWLQSLFSSILTVLFASLVIRIAMDFQGMILSHA
                     IRAAQTGNVNLVSTGAMGFMAGFLGALLVLIAKGFAVQLAGAGVEGAVQGAAMMGLGAA
                     GMATGKSLMLGGRAGLGFGLGMAGRTGMNSLSGKAGNLMGRGARTAAEWAGEKGYQALA
                     PTGALGMKARRLASLEKARARNAA"
                     /name="type IV secretion system protein"
     gene            14227..14913
                     /locus_tag="CR231_RS28620"
                     /old_locus_tag="CR231_28465"
     CDS             14227..14913
                     /locus_tag="CR231_RS28620"
                     /old_locus_tag="CR231_28465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_001290765.1"
                     /translation="MSEKIEKKIETAKSFERQLYAENERSKKNAWRVAVAASLLSLCLG
                     AAICVLVPLKEKELAIVAVGEKTGRTELITQVKQEKILQSEALGRYFVNTYITLREGYN
                     YPSLQYDYETVQLYSSNTVKDDYLRLYNSDMAPDKIYHNNGSYVAVEVISNIISDATAP
                     DKLASVRFKKTTRNFTTGQVSVSYWTARVTYRFEPEKSVKSSSRELNPLGFTVTSYQTD
                     REVRGE"
                     /name="type IV secretion system protein"
     gene            14910..15818
                     /gene="virB9"
                     /locus_tag="CR231_RS28625"
                     /old_locus_tag="CR231_28470"
     CDS             14910..15818
                     /gene="virB9"
                     /locus_tag="CR231_RS28625"
                     /old_locus_tag="CR231_28470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001299943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type conjugative transfer protein VirB9"
                     /protein_id="WP_001329500.1"
                     /translation="MMKKLFIATCLLLPGLVYSAATPLPSGFDARMQTVSYNGANTTVI
                     RSKTGFLTSVVFDEGEAVISAKAGFPAGWEITTDDNVVYINPRPVVQEQEGDEGEKLKK
                     VFQPTEKEWDTNLFVRTTKRIYSLDLILLSEEKQAQPAYVVQFRYPSEIAKKNAEEVRL
                     AKEKQEKLRQKKLISESFEKADAPKNWNYFMRVNEKYDSRRIAPDFAYDNGIFTFLGFN
                     SGKVFPAPFAVRDGQEQTLAFNVETKGKYKIMVIHNVNDKFVLRYGNSVVGVVNKSFGK
                     VLTDQRNTSSPAVERVEVNND"
                     /name="virB9"
     gene            15811..16929
                     /gene="virB10"
                     /locus_tag="CR231_RS28630"
                     /old_locus_tag="CR231_28475"
     CDS             15811..16929
                     /gene="virB10"
                     /locus_tag="CR231_RS28630"
                     /old_locus_tag="CR231_28475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB10/TraB/TrbI family type IV secretion system
                     protein"
                     /protein_id="WP_000131271.1"
                     /translation="MTDMKKTDDLVDDANQSKLESKPVHDIGDIRNKNNRMRSGFLFGL
                     MAVLVIGIFALKTYKNYFADDQQKASESTGDTSISQVSKIRTGLGQNFDPVENKAIINP
                     GATGSGNTVSDGHKEVPQEGFRKYLSIPVAGQGGSQTGASGSSRTSQTSEPQEERKESK
                     ENVPGKSGMKVTAINLDPDLYIEENRLIPCALTTRFVSDVAGRISCVFTEDVWSANHHT
                     KLLEQGTKAFGRYQTGTLNHGQGRMFVMWEQLRTPDNKRIDMVNTAAAGPLGEAGIDGW
                     IDSHFWERFGGSLMLSMVQDVAAAAADNAPGKDRNVDYTENSRQAMAEMAKVALENSIN
                     IPPTMYKNQGDIITIMVGEDIDFSDIYELKVK"
                     /name="virB10"
     gene            16931..17959
                     /gene="virB11"
                     /locus_tag="CR231_RS28635"
                     /old_locus_tag="CR231_28480"
     CDS             16931..17959
                     /gene="virB11"
                     /locus_tag="CR231_RS28635"
                     /old_locus_tag="CR231_28480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001401678.1"
                     /GO_component="GO:0043684 - type IV secretion system
                     complex [Evidence IEA]"
                     /GO_process="GO:0044097 - secretion by the type IV
                     secretion system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type DNA transfer ATPase VirB11"
                     /protein_id="WP_077250700.1"
                     /translation="MSGVIPVSISNKSLDFYKNQVFQSFLDIEGLTEIAVNRPGEIWTE
                     INGDWTFHNNNSVTFDFCKRFSHTLASFRGDEIGETKPLLSATLESGERVQVVFPPACE
                     RNTISITIRKPSTRQITHKEYVANGFYDYVQSGKKHRTYDDELLDLFRARNIAAFMELA
                     VAAGKTIVFAGATGSGKTTYMKSLIDFIPLNTRLITIEDAEEIKFFIHKNYVHLFYPSE
                     SGSDSGSIITAAKLIKSCLRMKPDRILLAEIKGGDAWDFVKVAGSGHSGSMTSIHAASA
                     KDAIIQMVTKCYQNRECQNLPFDVLRKIIMDSIDIVVHVGRDGVVRHMSDIYYKGAECE
                     NF"
                     /name="virB11"
     gene            17946..19808
                     /gene="taxB"
                     /locus_tag="CR231_RS28640"
                     /old_locus_tag="CR231_28485"
     CDS             17946..19808
                     /gene="taxB"
                     /locus_tag="CR231_RS28640"
                     /old_locus_tag="CR231_28485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxosome-coupling protein TaxB"
                     /protein_id="WP_170324155.1"
                     /translation="MKTFNKSQSVFIFAVMLVAAWFAGSFIFFVLYFSQIKNLKPLKAV
                     FRSIDAYRMDIFTDSLTLSVVTTDIRVLAFVALGAGFVVSLIIPVAALIKLNEKKENIF
                     GDARFATINDIRESNSFTLDGDEKDGIIVGIKDKKIIRYVGAAFSAMGAGTRAGKGAGI
                     VITNLMKYWWSVIILDPKRECFNITSLIRKVILGHEVYKFDPFSSVTHRFNPLYYVSMG
                     TSEGFNQLENLSLIIYPYKTDGADAGSYLNKTAGGVFKSYAVALWFMIKNDKAGLKTLD
                     IEPVFSMSKINQLFERAEPEHLLSFMNDIRSELRGKDKTLADIGVAGLKAFIEMEDKTK
                     AQLKSNFLNGLSPFANPNVANATDGNDFDLRQVRKKRMTIYFCISGDNARLAEKITNIF
                     FQLAIQVNLEKMPTDDPEIKHDCLFLLDEFPSIGAVDYIKSKSGLIAGYKLKLLIVYQV
                     GSQLEEIYSYAGSKTLLASAPCKIVYSASDVKDARELSEAMGTRTVTIGSKSKSRSRGG
                     TSRSESESLIERPLVTTNELLTLKFSEEILAMKGENPIRCEKAFYYLNEYFFGDFVKVA
                     PELANIFPRKKGKLVMPPQKVFENEIVAKGYLVVKDVPDLDKAA"
                     /name="taxB"
     gene            19817..20239
                     /locus_tag="CR231_RS28645"
                     /old_locus_tag="CR231_28490"
     CDS             19817..20239
                     /locus_tag="CR231_RS28645"
                     /old_locus_tag="CR231_28490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001353737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cag pathogenicity island Cag12 family protein"
                     /protein_id="WP_015059903.1"
                     /translation="MMKKLVFLLISILAGCSSPPEPTPVQFEKANEVINPSLPYVPDFH
                     GVIKSDVSGKGWVYEITSLSGVQARTPTFYYALAHADRIVVTTHDAGLWFRIRDLLKME
                     GATAVVEWRNEKSFLPEQVKIVFIKAQNEVKNDWKK"
                     /name="cag pathogenicity island Cag12 family protein"
     gene            20223..20528
                     /locus_tag="CR231_RS28650"
                     /old_locus_tag="CR231_28495"
     CDS             20223..20528
                     /locus_tag="CR231_RS28650"
                     /old_locus_tag="CR231_28495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000147044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbM/KikA/MpfK family conjugal transfer protein"
                     /protein_id="WP_000147044.1"
                     /translation="MTGKNRVVLPALLALGLISTNANASDPCASVLCLYGKAVGQGGGS
                     ECRSAEKDFFNILKKKKGSIRWSKTFDARKAFLNQCSTADPAAISKIMSKFGKVKG"
                     /name="TrbM/KikA/MpfK family conjugal transfer protein"
     gene            20534..20788
                     /locus_tag="CR231_RS28655"
                     /old_locus_tag="CR231_28500"
     CDS             20534..20788
                     /locus_tag="CR231_RS28655"
                     /old_locus_tag="CR231_28500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000415096.1"
                     /translation="MEKQTTDLLNVIKTGHSGSIAGNPAHALDDKTMNAIIHNYVATIV
                     LGKAGNCKETPLTKYCSRTMPERISVEEINEFKIYPELF"
                     /name="hypothetical protein"
     gene            20891..21199
                     /locus_tag="CR231_RS28660"
                     /old_locus_tag="CR231_28505"
     CDS             20891..21199
                     /locus_tag="CR231_RS28660"
                     /old_locus_tag="CR231_28505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000647576.1"
                     /translation="MKARSVRVAGIEIIDSVKTVAFVFTETLLFMVWFSAIVYGLYRVV
                     IVLWDDPLKPQSLMEFLNFIVELYSYVLPSLAVIAVALIAVLSICKILSAIWEGRKQ"
                     /name="hypothetical protein"
     gene            21196..21690
                     /locus_tag="CR231_RS28665"
                     /old_locus_tag="CR231_28510"
     CDS             21196..21690
                     /locus_tag="CR231_RS28665"
                     /old_locus_tag="CR231_28510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001215543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thermonuclease family protein"
                     /protein_id="WP_001215680.1"
                     /translation="MRHFLKALSFVVSLLPATLCAAEIQGKVIRVLDGDTIEIKTLPAK
                     IVVYEVPIRVRLINIDAPEKKQPFGRWSTSQLKTLVAGKQVTVSYSHKDRYGRIIGHVF
                     TTNGTDASRFMVQSGAAWVYERYNVDESLPALQREAQEQKRGLWADANPVPPWEWRYKH
                     N"
                     /name="thermonuclease family protein"
     gene            21706..22110
                     /locus_tag="CR231_RS28670"
                     /old_locus_tag="CR231_28515"
     CDS             21706..22110
                     /locus_tag="CR231_RS28670"
                     /old_locus_tag="CR231_28515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001576899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001218543.1"
                     /translation="MALSPKEKKELQQRFEKQLLPDLDMSFELNGEVYKFNFDKNESGD
                     YIDSFTQAVWGGYQDAEEWEKYGKHQETELPECPEPVEGWCDCDKCKSMIFHKEKNIYV
                     CLSCHKQTEPFLPIDWNSNDYDWLPYEDEY"
                     /name="hypothetical protein"
     gene            22216..22791
                     /locus_tag="CR231_RS28675"
                     /old_locus_tag="CR231_28520"
     CDS             22216..22791
                     /locus_tag="CR231_RS28675"
                     /old_locus_tag="CR231_28520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012908955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001199074.1"
                     /translation="MQYALVDALERKFLLDALEFGVLKDWKENPVKELPDIDESVHPFH
                     VCYGGYLLNPGVSDSDISRKIKDQTGFWLAAIDDTRMDCHSIAYYDIHTLPLILCGHQK
                     IVPFAALIKADECIISKIASYSGFAVTAFLRIKDQDIATNILNREGIFAFNGCERRFRQ
                     PVSEDNWQQAVSEERAIRCANRLIQCKG"
                     /name="hypothetical protein"
     gene            22796..24949
                     /locus_tag="CR231_RS28680"
                     /old_locus_tag="CR231_28525"
     CDS             22796..24949
                     /locus_tag="CR231_RS28680"
                     /old_locus_tag="CR231_28525"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247728.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003916 - DNA topoisomerase activity [Evidence IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="WP_001235745.1"
                     /translation="MRLFIAEKPAVANDIVKALGGNFTRHDGWFESDNAIVTNCFGHII
                     ESQPPENYNPEYKAWKVETLPLRLYPVKYQPVESAAKQVKTILELIRRGDVTEIVHAGD
                     PDDEGQLLVDEVLEYAGNTKPVKRVLINDNTLPAVKKALANLKDNRDFKGLYLKALARS
                     VADAVYGFSMTRAYTIPAKARGYQGVLSVGRVQTPVLGLIVNRTRANQNHKSSFYYTMT
                     GVFQRGADVIRANWKPGEFAPLTDRKLLDKAWADGTAASLAGKPATVEAAATDDKKTAA
                     PLPFNLVRLQQYMNKKFKMTAQKTLDITQQLREKYKAITYNRSDCSYLSDEQFSEAPQV
                     IDALKSVFPQSLDIDSARKSKAFNSAKVTAHTAIIPTASVPDVNALSTDERNVYLAIAQ
                     HYLVQFMPEKAYQEVSVAIQCGDESFYARARKTTDSGFEAFLGAETTDEGESEDNDDSA
                     FELLCKIRTGETLTTKEVIVNEKKTTPPPLFTEASLLAALVRVADFVTDPTIKKLLKDK
                     DKDKKDEHGGIGTPATRAAILETLKKRNYITLEKGKLIPTDTGYALIDALPGIAVNPDM
                     TALWSEKQAAIENGDLTVEQFINDLYGELTGMISDVDLGEMKIEPAAPAGQFQRLDSPC
                     PSCGKHIVIRPKGYFCTGCEFKIWSEFSGKKITQAQAEKLVKSGKTDLIKGFKKKSGGT
                     YDTVLVLEDKKTGKLGFPARAKK"
                     /name="type IA DNA topoisomerase"
     gene            24946..25152
                     /gene="hha"
                     /locus_tag="CR231_RS28685"
                     /old_locus_tag="CR231_28530"
     CDS             24946..25152
                     /gene="hha"
                     /locus_tag="CR231_RS28685"
                     /old_locus_tag="CR231_28530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin expression modulator Hha"
                     /protein_id="WP_000850859.1"
                     /translation="MKTKQEWLFQLRKCTSRDTLEKVIEINRYKLPLSESEAFYSAADH
                     RRAELVMNKLYDKVPSGVWKYVH"
                     /name="hha"
     gene            25170..25634
                     /locus_tag="CR231_RS28690"
                     /old_locus_tag="CR231_28535"
     CDS             25170..25634
                     /locus_tag="CR231_RS28690"
                     /old_locus_tag="CR231_28535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293133.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0030527 - structural constituent of chromatin [Evidence
                     IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="H-NS family nucleoid-associated regulatory
                     protein"
                     /protein_id="WP_001293134.1"
                     /translation="MSELTKEDEYGIISRTMMNIRSLRVFAREIDFEQLLEMQEKLNVV
                     IEERREDAEREAAERQELEAKRQQAIEYIISLGLDPESLLAPVTADTVKTRRKAKGGVR
                     KAKYRFKDENGEIREWSGNGKRPLALQKLLDEGHFMEDFLIEKTKPEQAE"
                     /name="H-NS family nucleoid-associated regulatory protein"
     gene            26380..26475
                     /gene="dqlB"
                     /locus_tag="CR231_RS29925"
     CDS             26380..26475
                     /gene="dqlB"
                     /locus_tag="CR231_RS29925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DinQ-like type I toxin DqlB"
                     /protein_id="WP_021534057.1"
                     /translation="MINMLIIVLRAVVAVANALIAVLELIRQFID"
                     /name="dqlB"
     gene            27138..27785
                     /locus_tag="CR231_RS28705"
                     /old_locus_tag="CR231_28550"
     CDS             27138..27785
                     /locus_tag="CR231_RS28705"
                     /old_locus_tag="CR231_28550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001694199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division plane positioning ATPase MipZ"
                     /protein_id="WP_000587671.1"
                     /translation="MIIVIGGDKGGTGKSHLATNLTVCLSQQGKRTGLVETDLNGSTKK
                     WNKRREQAGLPPVALNEAYGDISAKITKMADVAEILIIDTAGYDSTEFRTALKVADIVI
                     VPIDPLAQVEADSLQTVTKIVRDAQKINPRLAAHVLLYKCQPNTFSEQQELRDSLNSHD
                     YWLKPMKSTVSFLRAFVRAMNQGMGVHELKSNVSGASQAKAQIELLLKELEL"
                     /name="division plane positioning ATPase MipZ"
     gene            27860..28129
                     /locus_tag="CR231_RS28710"
                     /old_locus_tag="CR231_28555"
     CDS             27860..28129
                     /locus_tag="CR231_RS28710"
                     /old_locus_tag="CR231_28555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001086090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001086090.1"
                     /translation="MAKLELPELEQNQEVNATKFVQDAGKRPTENKTKLASFRIPNELL
                     EFIDNESKRLHRPKTKIIKAALLAYQDLDENELINLWFRADRND"
                     /name="hypothetical protein"
     gene            28290..28913
                     /locus_tag="CR231_RS28720"
                     /old_locus_tag="CR231_28565"
     CDS             28290..28913
                     /locus_tag="CR231_RS28720"
                     /old_locus_tag="CR231_28565"
                     /inference="COORDINATES: protein motif:HMM:NF022440.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2806 domain-containing protein"
                     /protein_id="WP_223369242.1"
                     /translation="MSLIDLSLSGLSEPGTKLIEKISDAIGVLYEPTRIRKKAKAEAEA
                     KRTELISRLELEGIEKRAVERFLKRETKRQENIENITMQAAQSLSESDNVSDIDEDWIE
                     AFFRECEDISDEQMQMLWGRILSEEAKSKGSFSRRTLKLLSTISKEEANLITYFGKFVW
                     QANKLTPILFTDENGDTEGITFDKLSVLDSLGVIQQGIGYSLTS"
                     /name="DUF2806 domain-containing protein"
     gene            complement(28902..29630)
                     /locus_tag="CR231_RS28725"
                     /old_locus_tag="CR231_28570"
     CDS             complement(28902..29630)
                     /locus_tag="CR231_RS28725"
                     /old_locus_tag="CR231_28570"
                     /inference="COORDINATES: protein motif:HMM:NF028536.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAP2 family protein"
                     /protein_id="WP_072651034.1"
                     /translation="MPYLSNKRLLAEMSIALVMAIVATLTLEHSQIDLMVADWFYLGMG
                     HWMVAKQAFLPDLLLYSGLKKLLMAMLIYLLVATICRAYHEKKGNAITAKWLVPVTKFR
                     VRELAYLVLTLILVPTVVASLKAYTHVVCPVHLTIFDGTLPYLPMLDSMRNTIPDKCFP
                     AAHASSGFALFAFAFAPSLRRRRGAIIIVVMALGWAMGCYKMIIGDHFLSHTVVSMMLA
                     WAMSAGLAWVFFKKGEQSRG"
                     /name="PAP2 family protein"
     gene            complement(29702..31327)
                     /locus_tag="CR231_RS28730"
                     /old_locus_tag="CR231_28575"
     CDS             complement(29702..31327)
                     /locus_tag="CR231_RS28730"
                     /old_locus_tag="CR231_28575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_049589868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine--lipid A transferase MCR-1.1"
                     /protein_id="WP_049589868.1"
                     /translation="MMQHTSVWYRRSVSPFVLVASVAVFLTATANLTFFDKISQTYPIA
                     DNLGFVLTIAVVLFGAMLLITTLLSSYRYVLKPVLILLLIMGAVTSYFTDTYGTVYDTT
                     MLQNALQTDQAETKDLLNAAFIMRIIGLGVLPSLLVAFVKVDYPTWGKGLMRRLGLIVA
                     SLALILLPVVAFSSHYASFFRVHKPLRSYVNPIMPIYSVGKLASIEYKKASAPKDTIYH
                     AKDAVQATKPDMRKPRLVVFVVGETARADHVSFNGYERDTFPQLAKIDGVTNFSNVTSC
                     GTSTAYSVPCMFSYLGADEYDVDTAKYQENVLDTLDRLGVSILWRDNNSDSKGVMDKLP
                     KAQFADYKSATNNAICNTNPYNECRDVGMLVGLDDFVAANNGKDMLIMLHQMGNHGPAY
                     FKRYDEKFAKFTPVCEGNELAKCEHQSLINAYDNALLATDDFIAQSIQWLQTHSNAYDV
                     SMLYVSDHGESLGENGVYLHGMPNAFAPKEQRSVPAFFWTDKQTGITPMATDTVLTHDA
                     ITPTLLKLFDVTADKVKDRTAFIR"
                     /name="phosphoethanolamine--lipid A transferase MCR-1.1"
     gene            31491..31748
                     /locus_tag="CR231_RS28735"
                     /old_locus_tag="CR231_28580"
     CDS             31491..31748
                     /locus_tag="CR231_RS28735"
                     /old_locus_tag="CR231_28580"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2806 domain-containing protein"
                     /protein_id="WP_223369243.1"
                     /translation="MRVFIICIFKSKNGRIGYYGTVFSVEFQSDDSSTWKLPIGTALLT
                     PIGQELMKICGSTPDIAYLNKFLNKINVEGSQVKLSIINM"
                     /name="DUF2806 domain-containing protein"
     gene            complement(31900..32427)
                     /locus_tag="CR231_RS28740"
                     /old_locus_tag="CR231_28585"
     CDS             complement(31900..32427)
                     /locus_tag="CR231_RS28740"
                     /old_locus_tag="CR231_28585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001473365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2726 domain-containing protein"
                     /protein_id="WP_000577043.1"
                     /translation="MIFNRNKKRDEQHNSAVVLPSAENVFSDFIKNNPALTTNAFTAIG
                     EVDCFTKVPLLSNNESEFLGILSRNIIPDYSVFPKIRLIEFVRPHGSEEAVKDLIREVQ
                     NITCDFVLKSYDETVLAVIQFGETATVRQQKKKLIIQRVCAMTGISFFEFKNTVDMMGS
                     EDFCQFLRDDEE"
                     /name="DUF2726 domain-containing protein"
     gene            complement(32562..32966)
                     /locus_tag="CR231_RS28745"
                     /old_locus_tag="CR231_28590"
     CDS             complement(32562..32966)
                     /locus_tag="CR231_RS28745"
                     /old_locus_tag="CR231_28590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012421203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_012421203.1"
                     /translation="MKDNIVDFQRIRDSMNDHSTDVANDAVYSDKKKISRFFYLLTPVR
                     YLLAASLYLVVVIPLGILAGFRFLLQFLGGIAVMGLTIAWYMGADVSSYVVLAAWIALT
                     VCGCAEQIFEWWIESRFAFRLFGIGRTPEE"
                     /name="hypothetical protein"
     gene            complement(32979..33845)
                     /locus_tag="CR231_RS28750"
                     /old_locus_tag="CR231_28595"
     CDS             complement(32979..33845)
                     /locus_tag="CR231_RS28750"
                     /old_locus_tag="CR231_28595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001473366.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_001353743.1"
                     /translation="MTTNKTSLSRLTKVRHRNELNSTLSTLPMAAKKVLFLAMCQINSK
                     NEFDDDHIFYVTVADYIKWVQVKPDAAYLALRDGSNILDTTLLKLKHDEILELSSDLGF
                     KFTKSNVPDSMNLSLTVFSTYYRNEGRVGIKFTKEAKRFLCKLIGEEKRYTTQVLLSVV
                     RLTSVNAASLYQLIRKIYSNNSRANSFEMTIDELKDELNLYTIGAGGVKDYKYPDYPAF
                     KRDVLNKSVKEIMKHTEVKNLSFVVSEKIGRKVYKLKFSYTIGYEGDTREDSEFTNMFD
                     KMYPPEN"
                     /name="replication initiation protein"
     ARG             complement(29706..31327)
                     /name="mcr-1.1"
                     /gene="mcr-1.1"
                     /gene_name="phosphoethanolamine--lipid A transferase
                     MCR-1.1"
                     /tool="amrfinderplus"
                     /drug_class="COLISTIN"
                     /identity="100.0"
                     /coverage="100.0"
     Typing          complement(32980..33851)
                     /name="IncX4"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          5986..7211
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="99.511"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          12619..13685
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.719"
                     /coverage="99.0"
                     /evalue="2.6999999999999997e-172"
     Typing          14228..14910
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="1.4399999999999998e-137"
     Typing          14911..15815
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.669"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          17947..19805
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="98.71"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 acactcttga taatcagact ttaacaccag aaacatgata ttacaacaca atcaatatca
       61 tgtttaaccg agtatcttct catgtttcat atctgtgatt tatctcacaa aggtaatcca
      121 tgctcaaaat ccacactgga ttcaaggcag attaacaaca gattcaaaat agattcacca
      181 gaaagaacaa cgaattagta ttcttatgac acattttgtg gatatcaccg aggaagctct
      241 catgtttaac cgaggaagct ctcatgttta accgaggaag ctctcatgtt taaccgagga
      301 agctctcatg tttaaccgag gaagttatca tgtttaaccg aggaagctct catgtttaga
      361 caaaaaacac gcttaaaatc aataaattag agctactcta agtttttaag tttttaagaa
      421 aaacaagaaa agataaggct tttaatgcgt gcgaatattc aggaactgtg gataactcaa
      481 caaaaccagc aacgatgatg gttccttacc ataaatctgt cccccgatga ttattacccg
      541 caagctaaaa caaacatcat caatcattaa aactcataac tttcaataac ataaaatcat
      601 caaaaaaata tttgatgcct tatgtatctc aattttcaag accataaatt tgtccctagt
      661 taactttaac ttattgaaat aaatataata ttcgtgcgta ctgatcctaa tgtcacatcg
      721 caaaaattcc gcttcctcgc tcactcagtc gctacgctcc tgccgttcgg ctgcggcgag
      781 cggtatctcc tttctcaaaa ccagagagat tcagatcata tgatccgtta tttgatcctt
      841 tttggatctt ccactaagaa gccctgaatc gcgctctgcc gcttcgttcg atacaaccat
      901 gaggaaaacc atgcgaaatg aaaaaaatcg cttaaaatgc gattcagagc gttttaggga
      961 ggttctgtta gttctcctgc attgcgcccg tagttcgcta acgctcacac gcgcagtaca
     1021 gcgccccgcc atgctgcaat gcaccagggc ggggtaaact cgcttgcgct cgcgctaact
     1081 gcggcattct gcggcgcaaa tcagcataat catggcctgc tggtcagttg ggctttgcag
     1141 ggtgaaggga tggcctgtgc accctggtac gttcgtcagc ggctgcgccg cgcttcgggg
     1201 cgatgtggct cctgtgctgc cctggtattt tcgttcgccc cttccatccg cttacgcgga
     1261 ttaaaaaacg tgataacaat cacttatcga gtaaaaaaac gggagaaaac ttgcaaatac
     1321 gacttaaagg tcgtattatt gtttcatcga aaggggaatg gcccctctca caatagccca
     1381 gcagggcagg agattaaaaa aatgaatatc caggaagcat taaacgtttt tggattatcc
     1441 ggcgaattaa ctgaaaaaga tatcaaagca gcatacagaa aagccgcttt aaaatatcat
     1501 ccagatcgta acccgttagg ggctgaactg atgaaagcgg taaatgcagc ttttgatgta
     1561 ttgatggcaa atattgataa aataaatcag ttccagagca ctgatgaaca tgcacgatat
     1621 aattacggtg atgacctgga aaaagtatta aacgttcttt ctggtttatc tggtctggta
     1681 tttgaagtga taggtaactg ggtctggatt agtggagaaa ccattacaca taaggaaact
     1741 ttaaaagaaa tcgggtgtaa atgggcggca aagaaaaaac aatggtttta tcgtccagac
     1801 gaacataaaa gttactggaa tcgtgaagaa cacacgatag aagaaatccg cgcaaaatac
     1861 ggtacaaccg gacagcgcag ggcgacaggg tggcaacgcg tggaaaccag agcgtaacca
     1921 gaacgggggc gagaagcccc cgatattata gccagcccgt cttttggggc atcgaaccca
     1981 aaaagacggg aacagcagcc acgtagcaaa aagggaaaca gatgaactct ttttttgaac
     2041 aatatcaccc tgtctttgaa gttgtctgcc gtatcctggg gaacggctgg cgcgtgaaca
     2101 aacttgatga ttgttcgtct cgtataaaac tgacgtcacc gcagtttaaa aattactctg
     2161 tgcatattcg gatggaaaaa gaccgctttt ctgtggtggg gagtgtggat agtcgttcct
     2221 ggcgtagtcc gcatcatgtt tgcacgttat ccagaaaacg gaatcccgtt gatattgcag
     2281 ccgatatcga gcgaaaaatt ctggtaaatg cttcgcagga ggtgttacag gcgattgagt
     2341 atgagaaaca ccaggtggaa aaaaaggacg aaattctgat cctgaaaggt atgttatcgc
     2401 aacttgtcca gcttgaaagc tggtatgggg cattgacagg ctttaaagct gaaaacggat
     2461 tgaacggtaa agtcaccgaa cagggcgaca gttatgattt acagattcgg ggcttgagta
     2521 tagatcaact tgttaaaatt acagggtatt tgaaacagtt atgagaaaaa ataaaggtga
     2581 tgtgacttat tttcttgaaa aagaaggtga caattacagg cttacaaaaa ggataaaagc
     2641 cagaacaaat gttaaaatcg ggaacaaaac tacgaaaatt acattgtatg atgctgtact
     2701 gaatgagaat gaattacaac atattgattt tacgtgtgcc ggattaaggg aagacgatga
     2761 gacgccagtt aagaatttaa ttaaggagtt tatgttaaat gaaacccgat aatacacctg
     2821 aaaatgtaaa aaaattacgt ttaaaagcag gattaacaca aaaggaatgc agtcatattt
     2881 atggtgttgg gctaagaacc tggcagaaaa aagaggaagt taatactcaa aacagtcaaa
     2941 gtctgtcact ggttgagttt gagtttcttt tgttacttgc aggagaacat cctgaatacg
     3001 tgctctgcaa aagggagtca aaataaaatg acctgtgatg gttttatatt agtacctgga
     3061 gttgcgctcg tagctcgctg acgctcacac gcgcagtaca gcgccccgcc atgctgcaat
     3121 gcaccagggc ggggtaaact cgcttgcgct cgcgctaact gcggcattct gcggcgcaaa
     3181 tcagcataat catggcctgc tggtcagttg ggctttgcag ggtgaaggga tggcctgtgc
     3241 accctggtac gttcgtcagc ggctgcgccg cgcttcgggg cgatgtggct cctgtgctgc
     3301 cctggtattt tcgttcgccc cttccatccg cttacgcgga ttaaaaaacg tgataacaat
     3361 cacttatcga gtaaaaaaac gggagaaaac ttgcaaatac gacttaaagg tcgtattatt
     3421 gtttcatcga aaggggaatg gcccctctca caatagccca gcagggcagg agatttaaaa
     3481 tgaaatgctc atctgttttt acttcaacca ctaatcatgt tttcacattc gaacgagtaa
     3541 cgctttgcac tattatcctt atgcataagg atactggaca acagtatgtt gtcatattta
     3601 ctgataacaa taaaattcgt gactataaag ccggaattgt tcctcagttt ggcgaactta
     3661 agcagagtga tgttgattta gtccttttct acagggacga atatgaaaaa tattttgatt
     3721 cattaaaaga tggcgatgaa tgcttgagtt ttaaagattt tattgagtgt ctttgttaag
     3781 cattatgaat gcaggggcat ccctgcattt tctggaaatt tcaatattga ttctgaaatt
     3841 gtctattaac atcaatgcaa gggaaattca tgaaaacgtt aaaacaagcc gcaatgcagt
     3901 ttgcatctga tctgcgtaat aatcgctgtt ttaaagctgc ttataatgat gctctgttag
     3961 agcttgatcg ggaagattta aacgccattg tacaatgcac atttcttttt gagccaaaac
     4021 gaacattagc cgaacttgat aaattaatta aaaagataga agtagaagaa gattatgagt
     4081 tttgtgtatc ccttgataaa ggtaaaggat tacacgaagt cagaacattt aaaagtgagc
     4141 gtgaggcgtt ggatgcttat cgcattttga ctctttacgg atacacagta actatagaaa
     4201 agaaggaggg taatgactga ctattcaagg tgtgatcagg ttgttccacc aacctgatca
     4261 cgttatcgac aatcaaaact gaatgaggtt tttaaatgtc aacgcggcag atcgtacagc
     4321 ttgctgattc ccttgtcaaa ggctgggaaa ccagaattcc ggcaatgaaa tttagcgaat
     4381 gggatcaatt ccggtggtgg ttaaactact tgcaagggta tgaaatgttt taaataaaaa
     4441 aaggggcttt ctgccccttt gtattttttg acaaaaatgc catgtgtaac tataattagt
     4501 tgcatatcta taggggatgg atttatgggg aaaacagata agctactggc aaagttttta
     4561 aacagtaaaa aaacgtttga atgggatgaa ctggtcgttt tgttttcctc tttgggatat
     4621 gtcaaaaagg aaatgcaggg gtcaagagtg cggtttttca atgctgaaat caatcacacc
     4681 atattaatgc atcgtccaca tccggaaagt tatatcaaag gtggtacgct gaaagcaatt
     4741 aaacagaatc tgaaagaggc tggattatta tgaaacattt aaaatataaa ggatatttag
     4801 gcacggttga acccgatttt gaaaataatg tcctgtatgg aaaactggcg tttattcggg
     4861 acctggtaac ttatgaggct tctacattag ctgaactgga acaggagttt aaaacatctg
     4921 ttgatctgta tttacagtct tgtgtggagg atggaaagga acctgatacc ccgtttaaag
     4981 gcgtgtttaa cgtcaggctt gatccagaac tgcatcgtcg ggtagcagaa atggcgatgg
     5041 aagaagattt atcgttgaat gcctttgtta ataaggctct ggaaaaagaa gtcagcaatc
     5101 atcgcgcagg ggcttaattg cccttgtttt tatgccctgt aagggcatgg gaggcgcttt
     5161 gcgccggaag ccccgcagcg cagcgaggac ttaaaaagcg ttacggcttc agccgtaaca
     5221 attcccagcc ctgccaggcc tgttttttct ttcacaaatc tttcagctat acgtttgcct
     5281 gatggtcgaa gacgaaagaa tctttcagca acgaaatctg gacatatgca gcgacgattt
     5341 tatagccagg cacagtgcca catatggtac aatcaatgca ggatagacaa tccgatgtca
     5401 aatgttaaca tttgaatcag attgtccaaa aacgatgttt ttgcctgtgc ctgccgcagg
     5461 ctctgttggg gtgacttatg aagatgatag cgttcaggct aagtgatgat gagttaaaat
     5521 ttgcagaaca taacgctatt ttaagtggat ttaccagtat caatgctttt gctaagcata
     5581 acgtgcttaa tattgaaacc aagcctgtta acatcccagt taataatgaa ccagcaaagc
     5641 tggtatcagt gcgtctttac cctcatgaaa tagaacttgt taaacgtaat gctgctcttc
     5701 acggcatgag catgagcaga gaaattgcta ttcgtgtgcg tcagtctttg ttaaagagtg
     5761 aagtctgtct ttaccctgat gaagttaagg aacttaaaaa actatcaact gctgtagatc
     5821 gtgttggtcg caacattcat tttatcataa aaggtgaaag attctgtacg gttaacgatc
     5881 cagatttcag aaaagacgtt attgaagtga ttgaactgtg taagcaaatt gattcaaaac
     5941 ttgaaacgtt aaccaagagt gttgttaaca gatttgggtg atttatgggt gtgtatgtag
     6001 aacaggaata ccgtattaaa cgcgctaaag ggactgggcg tgatccgaaa tctcctaagt
     6061 tatcgggaag acatatacat gccagtaaat cggcttttaa tcataaagtc agacatggtg
     6121 cggacaagaa agcatatacc tggacaccta caaaagaagt cacttttaaa atcactggct
     6181 caggtaaaac agccgcaggc atcaaaaatg gtattgatta cattacccgt aatggtgaac
     6241 ttgaggctta ctgttatgat ggaaaaggtt cagagcaaac agggaaagga gaagacttta
     6301 atagggagtt tacttcaact ttatctaaag gaaatgatta ctccaggaca tatcgtggag
     6361 aaaacatcga tcatgtgaaa aacatggtct tttcaccacc accagaagct ggagtaagca
     6421 gggaagacgc tctgaaagct acggtagaat ttcttaaaga gacttatcca aaccatgctt
     6481 tcgttgccgt ataccatgat gataaagaag atcatcctca tgtacatgtt aatattaaac
     6541 ttcgtgatga agaaacagga agaagattaa gacttactaa atctgaaacc aggaagttca
     6601 gaaacggttt tcatagaaaa ctgaaaggta tgggatatga tgttaccgct acctggaaaa
     6661 aagatcccga acgtaaacgg gagattgagc gattacaggc tgaaaatccg aaaagactcc
     6721 ggaatgttta caaggtggtg gattttgggg agacttcata tcagaataag gcaggggaaa
     6781 aacgaacacc tttcctcact tatgaaactt taaaaggtgg aaaacaggtt acgatttggg
     6841 gtaaagacct gaaaaatcat ttcgagtctg aaaagctcca gccaggaacg cttatcaaag
     6901 taaaaaaact ggctcctacg cttgtacgta gtccaatgtt taatgatgat ggaactgttg
     6961 caggctacag ggaaacgcat cgcaataact ggcagattga aaatattgcc cttgagcgga
     7021 acagagaacg tcaggttcat gagcgtgaaa ccaggcagcc ggaagagagc gacgttaaaa
     7081 agcagctatc cagaaaacat gagcaaggtc acaatatcgg gtttgctctt gaacacgggt
     7141 ttacaaagga ttcagaagaa cataaaaaac taagaataca gcaagagagg aactggaaag
     7201 gcctgggatt ttaatttgat tttggcgcag gtgaacaaag cggctacttt gctcacctgc
     7261 tgatcacaac aacctacgag ggaggttatc atgactgagc atgatgctat ctgcatttct
     7321 gcacttcatc aaatttttag tgatgaagaa catttgagtg agcaacaaaa agacattatt
     7381 ctgatgtacg cttatggcta taccctgaat gaaattgctg atttcaaagg actaaagcct
     7441 tcaactgtca gaaaatatct cgattctgta agagctgaac tgggaggtgt ctcgttggca
     7501 gggatcagaa cactggtact cattcggact aatgcccttc tcgtgtcaag tctttccagg
     7561 atcagtgaga gggggaattt atgaaaaaat atctgctttt tgctttgccg ttcttcgttg
     7621 ttggttgtag tgaagaagta aaaagtgtgg attggtgggg gcagcatctt acggaagcta
     7681 aacaaaagca ggcagagtgt gagaagtctg gctctgattc tcagaactgt aagaatgtta
     7741 aacaagcatt gtttattcag tctcagaagg atgctccagt ccctacattc gattaactaa
     7801 tgtttcaatc atactagagc gcccatatgg gcgctttttt ttgcatgatc acacgaatca
     7861 taatatgacc attttgtcaa tgttatttga tcgtattgtt gagcattgtt attttgcgaa
     7921 tcatgttcgc atctaaaaca aatccaaaac acacttatag tggattgatt aaatgaagga
     7981 gaaatcagat aagtcatcgg aaaaaggggt ttatgtcacg ataaaactcg atcccaggtt
     8041 gaatgcattt atcgaagaga aaacgaaaac atctttgctt agtaagagga agcaaattat
     8101 ttacttatta atgcagagta tgcgtattga tggatatatg gagcgttagc tatggcgtct
     8161 ttattcccag ccttgttgct gtgtgcggcg tcagttcatc cggatacgat aaatgatatt
     8221 gcacgggtcg agagtggctt caatccttat gctgtggctg aaattattcc tgaaagggaa
     8281 cgcggtagct atggcaaaag tgttatcagt catatgccca aaagtaagga ggaagctcta
     8341 acagttatca gagaaattga aaacagaaaa agacgttatt ctgtcggatt gatgcagatt
     8401 accagcagta atttttcttt ttattccacg tccgcagaaa aactccttga ttcgtgtgaa
     8461 aacttgtctg ttttcgaaaa gattatcgtg gattgttata aacgagggag gagcctggag
     8521 aatgcgctta gttgttacta tacaggaaat tttagtaacg gtaagcgaaa agaaaaagaa
     8581 tttaataata caagttatgt tgagcgaatt ggttatacag ggaacgaaaa aaaatatgtt
     8641 gtaccaggta caagaagcaa cgggggagaa cagcgaaaaa atcgttcaca caatgcgtca
     8701 gttatctggc ccgaaaccat tctgaaatct gcttttgttg ataactcaca tccaacaaaa
     8761 gttattaatt aacaggactt ataaaatgtc atttaagaaa tcagtatgta atcgtatcag
     8821 ttcatctgtc actgctgtaa tgcagcgtaa aaataaggta gttatggcag tcgccggggc
     8881 aacagttgca tcaccggcct ttgcggatgg attttcaaaa gcggaaacac tgctggaaaa
     8941 ggttaaaaca gggcttagtg gcctttcact ggtcacggtg actattgcct gtctgtgggt
     9001 cggctacaag gttctgtttg gtggaagcac gattcgtgaa tgctcaccta tcatcatcgg
     9061 ggcaattgtt atcgccagtg cggctgaagt tgcatcaatg atggttaact aataaagcgg
     9121 ggacgatagt atgtctacac tttataaagc gatgacacgc cctgctatgt atgtgggtgt
     9181 tcctgtcgtc cctcttactg tggttgcagg ggcgttattt ctggcggggg tttatatcag
     9241 caagctgatc tggctggcta ttcctgtcgc ggtttttgtt ctcagaatga tcactaaaca
     9301 ggacgaccac atttttaacc tttactttct taagctgaaa atgctcggaa actcagtgtg
     9361 taatcgtttt tttggcgcac gagcgttcct ctccggacaa tatgaagctg ttgaaattga
     9421 tgagtttgtt aatgccatga aactgaatga gcgaatcact actggtaaat atatacccta
     9481 ttcaagccat gttgataaaa atattgtcaa aacaaagaac ggtgattatg tagcgacatg
     9541 gcaactgatg gggattaact ttgagtcaat ctctgcggag atgttagaaa ctattgactc
     9601 acaggttgcc actcttgttc gttcattttc cggactgccc gtttcatttt ataaccattc
     9661 atgcagggcg agtttttatg atgcctttac cacaaaatca ggtaataaat atgctgatat
     9721 aatatcagat tgttactatg gttcgatgaa gaaaaataaa ttcaagggga acactcttta
     9781 ctttacgctg atctacagac cagatgggcg tgtagaaaaa ctggaaaaac gcaaaaaaag
     9841 tattaaagaa aagaaagatg atattaacat tcatgtgaag agaatgaatg aaatgattaa
     9901 tacattctct ggcgctcttg ataaatttac ctgtaaactt cttggtatgt atgaggagaa
     9961 cggaaaggta ttttcttctc aactgtcatt ctataattat cttctgacag ggaagttgca
    10021 aaaaatcaga gtcactgatt ctccggtgta taacgttctt ggtggagtgg atgtattttt
    10081 taatcatgat accggacaga tatgccgcat tgatggaaat aaattctttc gttctattga
    10141 aattaaagat ttctgtagtg agactgcatc cggtgttttt gatgtgctcc agtattctga
    10201 tgctgactat attattacgc attcatatac atccatgagc aaatcagaag cattgagtac
    10261 cattaaacgt gcggaaaaac agttaaagag tacagaagat gatgcggtta ctcaattgca
    10321 ggaactggaa aaggcaaaaa atgatattgt gtccggtgat atatcctttg gttactacca
    10381 tttcacgcta atggtaatgg cggacagtat cagggagctt gacgaatctg taagtaaaat
    10441 tacggcagac tttactgacc tgggcattat tccggcattg tcaaccatgt cattgccagc
    10501 ggcatatttt gcccaacttc cggcggtttt tcatttaagg ccgcgtttat ctccggtatc
    10561 gaatgtaaat tttgttgaac tggcatcatt ccataatttc taccagggga aacgcgataa
    10621 aaactgctgg acagaagcgg ttgctattct caaaacacca agcaaacagg cgtattatct
    10681 gaatttacat aactcagtac tgtttaaaga tgaaacaggt gaaaagaatc ttgctaatac
    10741 taaagttata ggaacggcgg gttcaggtaa gacaatgttt ctgtcatatc ttgcctgttc
    10801 attacagaaa tacaataacc ccgaaacttt tgctgattct gcaaaaaata agaagttaac
    10861 gtgtgtcttt cttgataagg acagaggggc tgaattatgt atccgaatgc ttggtgggga
    10921 atattacacc gtaaaaagcg gtgagccgac aggatggaat ccttttgctc tggaggcaac
    10981 aaaacgtaac cgtatttttg tcaagcaact gatggagatt ctgtgtacca gaaatggtga
    11041 aagattatcg acaagagaaa gattgcttat tagcgaaagt gttgatgctg tgatggattt
    11101 tcctcctggc gaaatgcggg aatatggcat taccagaatg cttgagcatc ttatgcagag
    11161 agatgatcgg gatgagcagg agaacgggat tatccttcgt ttgtcccaat gggctaatgg
    11221 tcaggctcat ggctgggttt ttgataatgc taaagacaca ttcaatattc agcatgtcaa
    11281 taattttggc attgatggca ccgagtttct tgatgatccg atggtatgtg caccaattac
    11341 tttctatctg ctgtatcgca ttacgcagct tctggacggt cggcgtcttg ttatcttcct
    11401 ggatgagttc tggaaatggc tacaggatga agcattcagc gactttgtct ataacaagct
    11461 gaaaacaatt cgtaagctga acgggctggt tattccggca actcagtctc cggatgaaat
    11521 actgaagaat aagatttcac gggctgtggt tgaagtatgc agcaccagta tttatctggc
    11581 taaccctgat gccgattaca atgattatgt ggaagggctt aagctgacac cagaagaatt
    11641 taatattgtt aaaaatcttg atccaatgtc gagacagttc ctgattaaaa aaagcagtct
    11701 taaaaagggg gatggtaaat cattttcagc acttgcgaca ctcgatttat cgggacttgg
    11761 tggatatctg aaaatattgt ctgccagtgc agataatctg gaaatttttg aaagtattta
    11821 tcatgaagga atggagcctg atgactgggt tcctgaatat ctcgaacggg caatctgaca
    11881 ggtgaattta tgaaacgtgt aaaaacattg atgctgatat cattattgac ggcttcattt
    11941 tatagtagcg caggaattcc ggttgctatt gatgccagtc cggaatgggc tgttgaagcc
    12001 gcaagatgga cagaacgact caaacaatgg tccgaaactg cgcaacatta tcagagtcag
    12061 attcaggcat ataaagacca gttagccacg gcaacaggta taaggaatat tgcggcattc
    12121 acaaatgaac taagtaatct acaatcagaa ctgacaaata tttataagca ggggaacagt
    12181 tatatttctg attttaccag taatcccgaa ggtgcattga gcagccaggc taaaaatctg
    12241 ttcagcaagt atggagcctt cgatatgtgt aatacgggct atgaacgtaa tgataatctc
    12301 tgtaaagcac ggattgtgtc aacggctgcc agtattgaac agggaaatga gatcaataag
    12361 cagttatcaa gtgcaatgtc tcagattcag agtttaagta gccgaattga ggcttcaaag
    12421 gatatcaaag aatcccagga tttggctaac gcattacagg cgcagtcgtt aaaaatgcag
    12481 gcgataaaaa tgcagtatga tgtctggaat aataaaaata aagcagatca tgagatgttg
    12541 gtcacacaag aacaagaggc ctttattaaa cagcagaaag aagctgaacc attaactttt
    12601 gattaaaagg tggatatatg gctcaggggt ttttcgttaa atataattct accgttatgg
    12661 attcggtaga taaaatcagc tccagttatc aaacacaatt tgctaatgat attatgtcgt
    12721 tagcgacggt atcggttacg ttatatgtac tatggaaagg atatcaaata cttgccagta
    12781 aaactcagac gcccttgcag gatttagtat gggatctatc aaaatttgca atcataatca
    12841 tgtttataac taatgcggat gggtatttaa ctgcggctac tgatgcgttg caaggcatga
    12901 aagatggttt ttctggaggg gtgagtgtct ggcaaacttt agataactta tggaaaagta
    12961 cgcaaaatct tggtgcggaa atatactctt tagataaatc aacatatgtt aaagatcaag
    13021 gtgtagttgg tcagttttta atatggactg gctcgcttat tttaatggct gttagtgtgg
    13081 ttgttttttt aacagcagat gtaacgatga aactcctgat tattacagca ccgatattta
    13141 tcttttgtct catgtttggt tttattcgga gcatgtttaa taattggtta caatcgttat
    13201 tctccagtat tctgacagtt ctatttgcca gtttagtgat tcggatagca atggattttc
    13261 aagggatgat cctttcccat gctattcgtg ctgcacaaac agggaatgta aatcttgtat
    13321 ctacaggtgc tatgggcttt atggctgggt ttttgggggc tttattggtt cttatagcta
    13381 aaggttttgc tgtccagtta gcaggtgcag gtgttgaagg tgctgttcag ggcgcagcca
    13441 tgatggggct gggtgctgct ggtatggcta ctggtaagtc tctgatgctt ggcggtcgtg
    13501 ctggtttagg ttttggctta gggatggccg gaagaacggg catgaattct ttatcaggga
    13561 aagcagggaa tctgatgggg cgtggtgcgc gaacagccgc tgaatgggcg ggtgaaaagg
    13621 gatatcaggc gctggctccg acaggtgctt tggggatgaa ggcgagaaga cttgcatccc
    13681 tggaaaaagc acgagcgagg aacgccgcat gaaaataatg aaacgttttt tttatgtgat
    13741 gtccctgaac tggatactgg tgttcgttga taaacatatc acctccggat ggagcaggaa
    13801 gagaaagcta ataacccagc ttgttatttt aatcacggga attaccttat ttaaggtctt
    13861 aggtggaatc agtcagagct ggttgtgaca tgcttcatta ttttgtcatg atactttatt
    13921 ttgtcctaat ccttctttta ggagtgttta cctgcttcgc aggaataaga cttggtttag
    13981 ggcttgcggg gaaatggaga aagggtatgg atcttcgctt tttgcttctt attggtggga
    14041 ttctttttct tcatcttggc ctttatctct taaaggtgtt cgtgaacgct taataaggtg
    14101 aatttatgcg atgtgtgatt cttttgtttt tcctgtttca gatttccgga tgtaccacaa
    14161 ggaataacct tccttctgat gtttccggcg aactggaacc cattaaccac agccaggtaa
    14221 tcagttatga gtgaaaaaat cgaaaagaag attgagacag ctaaatcctt cgaaagacaa
    14281 ctctatgcag aaaatgaacg gtctaagaaa aatgcatggc gtgttgcagt ggcagcatca
    14341 ttactgtcct tatgtcttgg ggctgcaatt tgtgttcttg tgccattaaa agaaaaagag
    14401 cttgctattg tggctgttgg cgaaaaaaca ggccgtacag aactgattac tcaggttaaa
    14461 caggaaaaga tcctgcaatc tgaagcactt gggcggtatt ttgtaaacac gtatattact
    14521 ttacgtgaag gttataatta tccgtctctt cagtatgatt atgagactgt acagctatat
    14581 agctcgaata cagtaaagga cgattatctt cgtctgtata acagcgatat ggctcctgat
    14641 aaaatttatc ataataacgg ttcttacgtt gcggttgagg tcatctccaa tattatttct
    14701 gacgcaaccg cgccagataa actggcctct gtgcgcttta aaaaaacgac gagaaacttc
    14761 acgaccggac aggtttcagt ttcatactgg acggctcgtg tgacatatcg ttttgaacca
    14821 gaaaagtcgg ttaaaagttc cagtcgtgag cttaatcctc tcggttttac tgtaaccagt
    14881 taccagacag atcgggaagt caggggggaa tgatgaagaa attatttatt gctacatgtt
    14941 tattgcttcc tgggcttgtg tattcagcag cgactccgtt accttctgga tttgatgcaa
    15001 ggatgcagac tgtgagttat aacggtgcga atacgaccgt tatccggtca aagacaggat
    15061 ttctcacatc agttgttttt gatgaaggtg aggctgttat cagtgcaaag gctggttttc
    15121 ctgccggatg ggaaatcaca accgatgata atgttgttta catcaatccg cgtcccgttg
    15181 ttcaggaaca ggaaggcgat gaaggcgaaa aactgaaaaa ggttttccag ccaacagaaa
    15241 aggaatggga tacgaatctt tttgtcagaa caacaaagcg gatttacagt ctggatctaa
    15301 tccttctgtc agaagaaaaa caagcgcaac ctgcttatgt tgtacaattc cgctatccat
    15361 cagaaatagc gaaaaagaat gcagaagaag taaggctggc aaaagaaaaa caggaaaaac
    15421 tcagacagaa gaaactgatt tctgaaagtt ttgaaaaagc cgatgcgcct aaaaactgga
    15481 attatttcat gcgagtcaat gaaaaatatg acagtcgtcg tatcgcccct gattttgctt
    15541 atgataatgg catatttacc tttttaggtt ttaactcagg gaaagtattc ccagctccat
    15601 ttgctgtaag agatggtcag gaacagacac ttgcttttaa tgtggaaaca aaaggcaagt
    15661 ataaaattat ggttatccac aacgttaatg acaaatttgt tttacgctat ggaaacagcg
    15721 ttgttggtgt tgtgaataaa tctttcggaa aagtattaac cgaccagagg aatacgtctt
    15781 ctcctgcggt agaacgtgtt gaggtgaata atgactgata tgaaaaaaac agatgattta
    15841 gttgatgatg cgaatcagtc aaagctggaa agtaaacccg ttcatgatat cggtgatatc
    15901 aggaacaaaa ataatcgtat gcgttctggc tttctgtttg gtctgatggc tgtattagtt
    15961 attggtattt ttgcgctgaa aacatataaa aattattttg cagatgacca gcagaaagca
    16021 tcagaatcaa caggcgatac cagcatttct caggtaagta aaatccgtac tggtcttggt
    16081 cagaattttg accctgttga gaacaaagca attatcaatc caggcgctac tggttctggt
    16141 aatactgttt ctgacggtca taaagaagtg ccacaggagg ggttcaggaa atatttgtca
    16201 atacctgttg ctggtcaggg agggagtcag actggcgcga gtggcagcag caggacatcg
    16261 cagacatcag agccacagga agaaaggaaa gaatcaaaag aaaatgtgcc tggtaaatca
    16321 ggaatgaaag taactgcgat taatctcgat cctgatctct atattgagga aaacaggctt
    16381 ataccgtgtg ctttaaccac acgctttgtt tctgatgttg caggtcgtat cagttgtgtt
    16441 tttacagaag atgtatggag tgctaatcac cacacaaaat tactggaaca gggaactaag
    16501 gcttttggtc gttaccagac cggaacgctg aatcatggac agggcagaat gttcgttatg
    16561 tgggagcagt tgcggacgcc tgataataaa cgaatcgata tggtaaatac agcagcagct
    16621 ggtcccctgg gagaagcggg cattgatgga tggatcgatt ctcacttctg ggagcgtttt
    16681 ggtggttctc ttatgctcag tatggttcag gatgtagcgg cggcggcggc ggataatgca
    16741 cctggtaaag atcgtaatgt ggattatacc gaaaactcac gacaggcaat ggctgaaatg
    16801 gctaaagtcg cacttgagaa ttcgataaat attcctccaa caatgtataa aaaccagggt
    16861 gacataatca ctattatggt cggggaagac attgattttt ctgatatcta tgagttaaag
    16921 gtaaaatagt atgagtggcg ttattcctgt cagcattagc aataaatcgc tcgattttta
    16981 taaaaatcaa gtattccagt cttttcttga tattgaaggg ctaacagaaa ttgctgtcaa
    17041 ccgtcctggt gaaatctgga cggaaattaa tggtgactgg acattccata ataataacag
    17101 tgtgaccttt gatttttgta aacgtttttc tcatacgctg gcatcatttc ggggagatga
    17161 aatcggcgag accaagccat tactttcagc aacactggaa tcaggagaac gtgtacaggt
    17221 cgtttttcct cctgcatgtg agagaaatac tatttcaatc actatacgta aaccatcgac
    17281 acggcagata acacataaag aatatgtggc gaacggtttt tatgattatg tccagtcagg
    17341 aaaaaaacac aggacatacg atgatgagct tcttgattta ttcagagcga gaaatatcgc
    17401 tgcttttatg gagcttgccg tagcagcagg gaaaaccatt gtatttgccg gagcaacggg
    17461 ttccggtaaa acaacttata tgaagagtct tatcgatttc ataccattga atacacggct
    17521 gattacgatt gaagatgcag aggaaatcaa attttttatc cataaaaatt atgtgcatct
    17581 tttttaccct tcggaatccg gcagtgattc cggctctatc ataacagcag cgaaattaat
    17641 caaatcctgt ttgaggatga aacctgacag aattttactg gcggaaatta aaggtggcga
    17701 tgcctgggat tttgtgaaag ttgctggttc tggtcacagt ggaagcatga cgtccattca
    17761 cgcggcctcg gcaaaagatg ccatcattca gatggtgaca aaatgttatc agaacagaga
    17821 atgtcagaat cttccttttg atgttcttcg taaaatcatt atggacagta ttgatattgt
    17881 tgttcatgta ggcagggatg gtgttgtcag gcatatgagc gacatctatt acaaaggggc
    17941 tgaatgtgaa aacttttaat aagtcgcaat ctgtttttat attcgctgtt atgcttgttg
    18001 cggcatggtt tgcaggttca tttattttct ttgtgcttta cttcagccag ataaagaatc
    18061 tgaaaccatt gaaggctgtg ttcagatcca ttgatgcgta caggatggat atttttacag
    18121 acagccttac tttatctgtt gtgactacgg atatcagagt tttagccttt gttgcacttg
    18181 gagcaggatt tgtcgtgtct cttatcatcc ctgttgcggc gttgataaaa ctgaacgaga
    18241 agaaagaaaa tattttcggt gatgcgcgat ttgcaacaat taatgatatt cgtgagtcta
    18301 acagtttcac gcttgacggt gacgaaaaag acgggattat cgttggtata aaagacaaga
    18361 aaatcatacg ctatgtggga gcagcattca gtgctatggg agccggaaca agggctggta
    18421 aaggtgctgg tatagtcatc actaatctta tgaagtactg gtggagtgtt attattctcg
    18481 atccaaaaag ggagtgtttt aatatcacca gtcttatcag gaaggtgatt ttaggtcatg
    18541 aggtttataa atttgatccc tttagttcgg taacgcaccg ctttaaccct ttgtattatg
    18601 tcagcatggg aacgagtgaa ggttttaatc agcttgaaaa tctttcgttg attatttacc
    18661 cctataagac agatggtgcg gatgctggta gctatcttaa taagacggcg ggtggtgttt
    18721 ttaaatctta tgctgtcgct ttatggttta tgattaagaa tgataaggct ggactaaaaa
    18781 cgcttgatat tgagcctgtc ttctcaatgt ctaaaattaa tcagcttttt gagcgtgcag
    18841 aacccgaaca tcttctttca ttcatgaatg atattcgttc agaattaagg gggaaagaca
    18901 aaacgcttgc tgatattggt gtcgctggcc ttaaggcatt cattgagatg gaggataaaa
    18961 caaaagcaca actcaaaagc aactttctta atggattatc accgtttgct aaccccaatg
    19021 tggcaaatgc tactgatgga aatgattttg atttgcggca ggtgcggaaa aagcggatga
    19081 caatttattt ctgtatttct ggtgataatg ccaggttggc tgaaaaaata acaaatattt
    19141 tctttcagct tgctatacag gtgaatcttg aaaagatgcc aacggatgat ccggaaataa
    19201 agcatgactg cctttttcta ctggatgaat tcccgtcaat tggtgctgta gattacatca
    19261 agagtaaatc tggtctcatt gctggttaca agctgaaatt gttgattgtt taccaggtcg
    19321 gctctcagct tgaggaaatc tacagttatg caggcagtaa aacattactg gcaagtgcac
    19381 cctgcaaaat tgtttattcc gcttctgatg ttaaagatgc gcgggagtta tcagaagcga
    19441 tggggacacg aacagtaact atcggttcga aaagcaaaag tcgtagtcgt ggaggaacat
    19501 cgagatctga atcagaaagc cttattgagc gtccactggt aacaacaaat gaactactta
    19561 cactgaaatt tagtgaagaa atcctggcaa tgaagggaga aaacccgatt cgttgtgaaa
    19621 aggcattcta ctatctcaat gagtatttct ttggtgactt tgtgaaggtt gctccggaac
    19681 ttgcaaacat tttccccagg aagaaaggaa agctggttat gcctccacag aaagtatttg
    19741 aaaatgaaat cgtcgcaaaa gggtatctgg tagtaaaaga tgttcctgat ctcgataaag
    19801 cggcataaag gagaacatga tgaagaagtt agtgttttta ttgatttcca ttcttgctgg
    19861 ttgttcatca ccgccagagc caacacccgt gcagtttgaa aaggcaaatg aagtgatcaa
    19921 tccctcattg ccatatgtcc ccgattttca cggtgtcata aagtcagacg ttagcggtaa
    19981 aggatgggtt tatgagatca cttccttatc cggagtacag gccagaacgc cgacgtttta
    20041 ttacgctctg gctcatgcgg acaggattgt agtgacaaca catgatgctg ggctgtggtt
    20101 tcgaatcaga gatctgttga agatggaagg ggcaacagca gtcgtggaat ggcgaaacga
    20161 gaaaagtttt ttacctgaac aggtaaaaat agttttcatt aaagcacaaa atgaggtgaa
    20221 aaatgactgg aaaaaataga gtggttttac cagccttgct ggcgttagga ttaatatcaa
    20281 caaatgctaa tgcatctgac ccttgcgctt cggtactttg cttatatgga aaagcagtcg
    20341 ggcaaggtgg agggagtgaa tgcagaagtg ctgaaaagga tttttttaat attctgaaaa
    20401 agaaaaaagg aagcattcgc tggagtaaaa cttttgatgc ccgtaaagca tttctgaatc
    20461 agtgttcaac ggctgatcct gctgctatat caaaaatcat gagtaagttc ggcaaggtta
    20521 aagggtagat gatatggaaa agcaaactac tgatttactg aatgtaatca agacaggaca
    20581 ctctggctca atagctggta atcctgctca tgcactggat gataagacta tgaacgccat
    20641 cattcataac tacgtggcaa cgattgtgct cggtaaagca ggtaactgca aagaaactcc
    20701 tctcacaaag tattgttcga ggactatgcc agagcgtatt tcagttgaag aaattaatga
    20761 gtttaaaatt tatccagagt tattctgaac ggagataacg gcaaacgccg cagattccgg
    20821 attttaatcc gggatttgcg gggttgaaca accgaagggc gttagtttcc tcgtaatcca
    20881 tgaggtgtat atgaaagcaa gaagtgtgag agttgccgga attgaaatta tcgatagtgt
    20941 taaaacggtc gcttttgttt ttactgaaac cttactgttt atggtctggt tttcggcaat
    21001 tgtctatggg ctttatcgtg ttgttatcgt tttatgggat gatcctttaa agccgcaatc
    21061 gctcatggaa tttcttaatt tcatagttga gttgtatagc tatgtacttc cttcgttggc
    21121 tgttatcgca gtggctttaa tcgccgtttt atccatttgt aaaatactct cagcaatatg
    21181 ggagggaaga aagcaatgag acattttctt aaggctcttt cctttgttgt ttccctgtta
    21241 ccagctacat tgtgtgcggc tgaaatccag gggaaagtta ttcgcgttct cgatggcgac
    21301 accatagaaa ttaaaacact acccgcaaaa attgttgtgt atgaagttcc gatccgagtc
    21361 cgattgataa acatcgatgc ccctgaaaag aaacaacctt ttggacgctg gtcaactagt
    21421 cagcttaaaa ctctggttgc aggtaaacag gtgacagtct cttattcaca taaagaccgc
    21481 tacggacgca ttatcggtca tgtgttcacg acgaacggca cggatgccag ccgctttatg
    21541 gttcagtctg gcgctgcatg ggtatatgaa cgttacaacg tggatgagtc attaccggct
    21601 ctgcaacggg aagcgcagga acaaaaacgc ggtttgtggg ccgatgcaaa tccggttcca
    21661 ccgtgggaat ggcgatacaa acataactaa ctgatagagg tttttatggc tttatcaccc
    21721 aaagaaaaga aagagttaca acaacgcttc gaaaagcaat tactacctga ccttgatatg
    21781 tcatttgaac taaatggcga agtatataaa tttaattttg ataaaaatga gtcaggtgac
    21841 tatatcgata gttttacaca agcagtatgg ggaggttatc aggatgccga ggaatgggaa
    21901 aaatatggta aacatcagga gacagaatta cctgaatgcc ctgaaccagt cgagggttgg
    21961 tgcgactgtg ataaatgtaa gtcgatgatt tttcataaag agaaaaatat ttatgtttgc
    22021 ctctcctgcc ataaacaaac agagccattt cttccaattg actggaactc aaacgattac
    22081 gattggctac cttatgaaga tgaatactaa tgctgaatac ttcacagtca taatacagat
    22141 tgttctttat tcaaaagaca accatctatt gaaagtgcat tagttatata aatcagatac
    22201 tctttggtgg ttattatgca atatgcatta gttgatgcgc tggaacgaaa atttttgctg
    22261 gatgctcttg aatttggtgt tctgaaggac tggaaagaaa atccggtaaa agaacttcct
    22321 gatattgatg aatctgttca ccccttccat gtctgctatg gtggatattt attaaatcct
    22381 ggtgtttcag attcagatat tagcagaaaa ataaaagacc agacaggatt ctggctggca
    22441 gctattgatg atacccgcat ggattgtcat tcaatagctt attatgatat tcacaccctc
    22501 cctttgattt tgtgtggaca tcaaaagata gttccttttg ccgcattaat aaaagctgat
    22561 gaatgcatca tttcaaaaat tgcttcatat tctggttttg ctgtaacagc ttttttgaga
    22621 attaaagacc aggatatcgc aacgaatata cttaaccgtg agggaatttt tgcctttaat
    22681 ggctgtgagc gcagattcag acaacctgta agtgaagata actggcaaca ggcagtatca
    22741 gaagaacgcg ctattcgttg tgcaaacaga ttaattcaat gtaaaggata acaaaatgag
    22801 actttttatc gcagaaaaac ccgcagtagc aaatgatatt gttaaggcac ttggtggcaa
    22861 ttttacccgc catgatggct ggtttgaaag tgataacgcc attgtgacta actgttttgg
    22921 tcatattatc gaatcacagc cgccggaaaa ctataatcct gaatacaaag cctggaaggt
    22981 tgaaacgctt cctttacgtc tttatcccgt gaagtatcag cctgttgaaa gtgcagcaaa
    23041 acaggttaaa acgattctcg agcttatcag acgtggagac gtgactgaaa ttgttcacgc
    23101 tggcgatcct gatgatgagg gacagctact tgttgatgaa gtcctggaat atgcaggaaa
    23161 cacaaaaccc gtaaagcgcg ttctgattaa cgacaacacg cttccggcag tgaaaaaggc
    23221 actggcaaat cttaaagata atcgtgattt caaagggctt taccttaagg cgctggcgcg
    23281 ttcagttgct gatgccgtct atggcttctc catgacgcgt gcttacacca ttcctgcaaa
    23341 agccagagga tatcagggcg ttctgtctgt cgggcgcgtc cagactcccg ttcttggcct
    23401 gattgtgaat cgtacccgtg ctaaccagaa ccataaatcc agtttttact acaccatgac
    23461 cggagtcttt cagcgtggtg ctgatgttat cagggcgaac tggaagccag gggaatttgc
    23521 tccgctgaca gaccgtaaat tacttgataa agcgtgggca gacggaacgg ctgcatccct
    23581 tgcaggaaaa ccggctacag ttgaagcagc agcaactgat gataaaaaaa cggctgcgcc
    23641 gttgccgttt aatctggtca gactccagca atacatgaac aagaagttta aaatgacggc
    23701 acaaaaaacg ctggatatta cgcaacaact acgcgaaaaa tataaagcaa ttacgtataa
    23761 ccgctctgac tgctcatatc tttcagatga acaattcagc gaagcgccgc aggttatcga
    23821 tgccctgaaa tcagtctttc ctcagtcgct ggatattgat tctgcacgta aaagcaaagc
    23881 gtttaacagt gcaaaggtga ctgcgcatac tgcgataatc ccgaccgcca gtgtgcctga
    23941 tgttaacgca ctcagcaccg acgagcgcaa tgtttacctg gcgatcgcac aacactatct
    24001 tgttcagttc atgcctgaaa aagcatacca ggaagtatcg gttgccattc agtgtggtga
    24061 tgagtcgttc tatgcccgtg ccagaaaaac aactgacagc ggatttgagg cgtttcttgg
    24121 cgcggaaacc acagacgaag gtgaatcaga agataatgat gattccgctt ttgaactgct
    24181 ctgtaaaatt cgcacaggag aaacactgac gacaaaagaa gttattgtta atgagaagaa
    24241 aacaacaccg ccgccgttat tcaccgaagc ctccttgctt gctgcgcttg ttcgtgtcgc
    24301 ggattttgtc actgatccaa caattaaaaa attgttgaag gataaggata aagacaaaaa
    24361 agatgaacat ggtggcattg gtacgccagc tacccgcgca gccattctgg aaacgctgaa
    24421 gaaaagaaac tatatcacgc tggaaaaagg gaaacttatt cctactgata ccggatatgc
    24481 gcttattgat gccctgcctg gtatagcggt taatcctgat atgacagcat tatggtctga
    24541 aaagcaggct gccatagaaa atggcgacct gacggttgaa cagtttatta atgatctgta
    24601 cggtgaactg acaggcatga tttctgatgt tgacctgggc gagatgaaga ttgaacccgc
    24661 tgcgccagca gggcagtttc aacgcctgga ctctccctgc ccttcctgtg gtaaacatat
    24721 tgttatcagg ccgaaaggtt atttctgtac cggatgtgaa tttaaaatct ggagtgagtt
    24781 ttctggtaag aaaatcaccc aggcacaggc cgaaaaactg gttaaatcag ggaaaaccga
    24841 tttgattaag ggatttaaaa agaaaagtgg tggaacgtat gatacagttc ttgtccttga
    24901 ggataagaaa acagggaagc tgggttttcc ggcaagggct aagaagtgaa aacaaagcag
    24961 gaatggcttt ttcagttaag aaaatgtaca tcaagagata ctcttgaaaa agttattgag
    25021 attaaccgtt acaaactgcc tttatcagaa tcagaggcat tttattctgc cgcagatcat
    25081 cgccgagcag aactggtgat gaataaactt tatgataagg tgccttccgg cgtctggaag
    25141 tacgtacact aaataagagg attaattata tgagcgaact gactaaagaa gatgaatacg
    25201 gcattatcag ccgtactatg atgaatattc gttcattgcg tgtttttgcc cgtgagattg
    25261 attttgagca gttgctcgaa atgcaggaaa agctcaacgt tgttattgaa gaacgtcgtg
    25321 aagatgctga acgtgaagcg gctgaacgcc aggaacttga agccaaacgt cagcaggcca
    25381 ttgaatacat catatcttta ggtcttgatc ccgaatcact ccttgctcct gtaacagcag
    25441 atacagtaaa aaccaggcgg aaagccaaag gcggagtaag aaaggctaaa taccgcttta
    25501 aggatgaaaa tggcgagatc agagaatggt ctggtaatgg caagcgtccg cttgctttac
    25561 agaagctgct tgatgagggg catttcatgg aagatttcct cattgagaaa actaagccgg
    25621 aacaggcaga ataacccgcc aggtatacat cacacagaca tacacatagg tatgtctgtg
    25681 tgacatacct atgtacagtg ccagatggcg ttgctacgtg aaaaataacc taccctaccc
    25741 ctgctttttt cgcagatttt acgtagcaca ccgttgctat agcattcatc taaaaagctg
    25801 aatgtccttt tctgtcgctg ttgcatttta attcactgaa aaatattgag taatgaaaat
    25861 gccggtaacg cgtcaagctg ttggccaacg cgacaggcag tattggaagc aacaaaaaaa
    25921 atgaaagaaa aatccctcaa atgaaggaga aaaaacggaa ctacagccga acgacaggca
    25981 caaaaaaacc cgactggtaa tcgggctttt ttgcgttttc cagtcttgag ttggtggctc
    26041 tgaccggaga aggttactct acacctaacg tttacatttt attcactatg gtgctgtaaa
    26101 gcaactaaat gtggttaagg aaccacattt agtggtgtaa cgggtgtttt gtgtagcgta
    26161 taatcagtca gttagtcatg tagttggctt gcaatcctgc tgttcccgta tctgcgggta
    26221 tgaacgattt taaagtcctg gctggataaa caggtggtgc tgtattcggt gctctggcag
    26281 gaggaggtca ctctacacct aacaatgcga gagagccgtt gtgacaggca gtgtatgagc
    26341 aagcaacggt gatttcctcc agttttactg gagaaacgga tgattaatat gttaatcatc
    26401 gttctcagag ctgtggtcgc cgttgcaaac gcgctgattg cagttctgga actgatccgc
    26461 caattcatcg attgatgaca acggaaacgt aactaagggc aggaagtgaa ccgcttcctg
    26521 ccctttaaca aaaaaggagg atttatggat tttatgagca ttttggggcg ctgtttactt
    26581 cttcctttcc ctgttgcgat gtttgtcggt tgcctgtttc ctggcatcga tgatcgctta
    26641 tccggaatgc ttatgagtgt tgctgtggga tgtttatcgt ggtatgtcac cagaccgaag
    26701 aaccgacaga caaaggccgc gtaagtggcc tttaattggg atacccttta gttacaacat
    26761 tctaatagct cattccatcc tccgctcatc cagcaaacat aacctccctg cccctcccca
    26821 ctacagaaag tggcgcgccc cgcccgtacg ggcggaatct aatcgcttaa ttttgaatgt
    26881 tgtaactaaa catactcatt gctgtattgc cacaaggttt cgcagcaagg gaggataccg
    26941 aaagtaacgc tgtcactttt gctttcaagt gaccaaccaa cgggtacatc acactgacat
    27001 acaataatgt atttcttcat gatgtacatc attgtaattc attgtgacat acactatagt
    27061 atgtccatgt gacatacgca tgcgtacatc acatagaaat acacatgagt aaatcactgt
    27121 gacatacaag gggtactatg attatcgtaa tcggtggtga taaaggcggt acaggtaaat
    27181 cacatctggc aaccaactta actgtttgcc tctcacaaca gggaaagaga acggggcttg
    27241 ttgaaacaga cctgaatggc tcgaccaaaa aatggaataa acgcagagaa caggccggat
    27301 taccgcccgt cgcattaaat gaagcctatg gcgacatcag tgccaaaata acaaaaatgg
    27361 cagatgtagc agaaatcctc attatagata ctgccggata tgacagcacg gagttcagaa
    27421 ctgcactaaa agttgcagac attgtgattg tcccgatcga cccgcttgcc caggtggaag
    27481 cagacagtct tcagactgtg acaaaaattg tcagggatgc gcaaaaaata aatcccaggc
    27541 tggctgcaca tgtgctcctg tataaatgcc agccaaatac gttcagtgaa caacaagaat
    27601 taagagactc tctcaacagc catgattact ggcttaaacc aatgaaaagc acggtttctt
    27661 ttctccgggc ctttgtaaga gcaatgaatc agggaatggg ggttcacgag ttaaaaagta
    27721 atgttagcgg tgccagccag gcaaaagcac aaatcgaact cttgctgaaa gaactggaac
    27781 tgtaaatcat agtgacatac actaatgtac atcatcatga tatacattag tgtgaaacaa
    27841 tcagattaga aggtacatca tggcaaagct ggaactacca gaactagaac aaaaccagga
    27901 agtgaacgcc acaaaatttg ttcaggacgc aggaaaacgc cccacagaga acaaaacaaa
    27961 actggcttca ttccgcatac cgaatgaatt gcttgaattc attgataacg aatcgaaaag
    28021 actgcatcgt cccaagacaa aaataatcaa agcagcatta ctggcttatc aggatctgga
    28081 cgaaaacgaa ctcattaatt tgtggttcag agctgacaga aatgattaat catagcaagt
    28141 ggcccaataa actctttatc attttctttt agatacttat ctgaatgtac taacttcatc
    28201 acttttaaat gtagttgtga ttcattttta gttactcttg caataaaata cccttgtaca
    28261 gttgttgcac gggtatttag gagcactaga tgagccttat cgatttaagt ttatcaggat
    28321 tatcagaacc aggaacaaaa cttattgaaa aaataagtga tgctattggt gtgctttatg
    28381 aacctacaag aatcaggaaa aaagcgaagg ctgaagctga agctaaacgc acagagctaa
    28441 tttctaggtt agagcttgag ggaatagaaa aacgggcagt tgagcgtttt ctcaaacgtg
    28501 aaacgaaacg acaggaaaac attgaaaata taacaatgca agcagcacaa agtctatctg
    28561 agagtgataa tgtttctgat attgacgaag attggataga ggctttcttc agggagtgtg
    28621 aggatattag tgacgaacaa atgcaaatgc tttggggaag aattttatcc gaagaagcaa
    28681 agtcaaaagg ttcgtttagt cgtagaacct taaaactatt atccactata agcaaagaag
    28741 aagcgaacct tattacttat tttggaaagt ttgtttggca ggcaaacaaa ctcactccaa
    28801 ttttatttac cgatgagaat ggagatactg aaggtataac tttcgataaa ctttcggttt
    28861 tagactcctt aggcgttatt caacaaggca ttggttatag tttaacctct tgattgttca
    28921 cccttcttaa aaaacaccca cgcaagccct gccgacatcg cccacgcaag catcatcgac
    28981 accaccgtat ggctcaaaaa atgatcgcca ataatcatct tatagcagcc catcgcccag
    29041 cccaatgcca tcaccacgat gatgatcgca ccacgacggc ggcgcaaact tggcgcaaac
    29101 gcaaaggcaa acagcgcaaa tccgctactg gcatgcgccg caggaaagca cttatcagga
    29161 atggtgttac gcatactatc aagcatcggc aaatacggca gcgtaccatc aaaaatcgtc
    29221 aaatgcacag ggcagaccac atgagtatat gccttcaatg acgcgacaac tgtcggcact
    29281 aggatcaaag tcagcaccag atacgcaagc tcacgcacgc gaaattttgt cactgggaca
    29341 agccacttgg cagtgatagc attgcccttt ttctcatgat aagcacggca aatggtcgca
    29401 accagcaagt agatcagcat cgccatcagc agctttttta gtccagaata cagtagcaaa
    29461 tctggcaaaa aagcttgctt ggcaaccatc caatgcccca tacccagata aaaccaatca
    29521 gcgaccatca gatcaatctg actgtgctca agggtcagcg tggcaacgat cgccatgaca
    29581 agagcgatac tcatctcagc aagtaggcgt ttatttgata aatacggcat aacaaacccc
    29641 accccaccgc ccataatacg aatggagtgt gcggtgggtt tggaaaaaat acagggagaa
    29701 atcagcggat gaatgcggtg cggtctttga ctttgtccgc ggtgacatca aacagcttta
    29761 ataatgtcgg cgtgatcgcg tcatgggtca ggacggtatc ggttgccatt ggcgtgatgc
    29821 cagtttgctt atccgtccag aaaaatgcag gcacactgcg ctgttctttt ggtgcaaagg
    29881 catttggcat accatgtaga tagacaccgt tctcacccag actttcgcca tgatcgctga
    29941 catacagcat tgagacatca taggcattgc tgtgcgtctg cagccactgg atactttgag
    30001 cgatgaaatc atcggtggca agcaaggcat tgtcataagc attgatcaag gactgatgtt
    30061 cgcacttggc aagctcatta ccttcacaca ctggcgtgaa tttggcaaac ttttcatcat
    30121 atcgcttaaa atacgcaggc ccgtgattgc ccatttggtg cagcatgatc agcatatctt
    30181 tgccgttatt ggcagcgaca aagtcatcta agccaacgag cataccgaca tcgcggcatt
    30241 cgttataagg attggtgttg cagatggcgt tgttggtcgc ggatttataa tcggcaaatt
    30301 gcgcttttgg cagcttatcc atcacgcctt ttgagtccga attattatca cgccacaaga
    30361 tacttacgcc caagcgatcc agcgtatcca gcacattttc ttggtatttg gcggtatcga
    30421 catcatactc atccgcgccc agatagctga acatacacgg cacagaatac gccgtcgatg
    30481 tgccgcacga tgtgacattg ctaaaattgg tcacgccatc gatcttggca agctgtggga
    30541 aagtatcgcg ctcatagcca ttgaagctga catgatcggc gcgtgccgtc tcaccgacga
    30601 cgaacaccac taggcgtggc ttacgcatat caggcttggt tgcttgtacc gcgtctttgg
    30661 cgtgataaat ggtatctttt ggcgcactgg cttttttata ctcaatactg gcaagcttac
    30721 ccaccgagta gattggcatg atcggattga catagctacg cagcggctta tgcacgcgaa
    30781 agaaactggc ataatgactg ctgaacgcca ccacaggcag taaaatcagc gcaagacttg
    30841 ccacgatcaa gcccaatcgg cgcatcaaac ccttgcccca agtcggataa tccaccttaa
    30901 caaaagccac aagcaaactt ggtagcacac ccaaaccaat gatacgcatg ataaacgctg
    30961 cgtttaatag atccttggtc tcggcttggt cggtctgtag ggcattttgg agcatggtcg
    31021 tatcatagac cgtgccataa gtgtcagtaa aataactggt caccgcgccc atgattaata
    31081 gcaaaatcaa cacaggcttt agcacatagc gatacgatga taacagcgtg gtgatcagta
    31141 gcatcgcgcc aaagagcacg acagcgatcg tcagcacaaa gccgagattg tccgcgatgg
    31201 gataggtttg gctgatttta tcaaaaaagg taagattggc ggtcgcggtc aagaaaacgg
    31261 caacactcgc cacaagaaca aacggactga ccgagcgtcg ataccacaca gaagtatgct
    31321 gcatcatgag aaactactca aaaaataaac ggtgggataa ttgcggcaat tatactgcaa
    31381 ttttttaaga aatccagtac aatttatctg atataaaaaa ttatgcgata cagaaatatt
    31441 tcagaaattt tattaggcaa tcattgcgca atcccatact gaatatacac ttgagagtat
    31501 ttataatttg tatctttaaa agtaaaaacg gtcgtatcgg ttattacgga acggtttttt
    31561 cagttgagtt tcaaagcgat gattcatcaa cctggaaact accaatagga acggctttac
    31621 ttacgcctat cggtcaagaa ttgatgaaaa tatgcggttc cactccagat attgcgtatt
    31681 taaataaatt cctcaacaaa ataaatgttg aaggaagcca ggtaaaacta tcaattatta
    31741 atatgtaaag aggtcgagtt acctgtctga gttccactaa ccataattaa aagcgaccgc
    31801 aaaaactgcc cagtgaaaac tgtgttgcca gtaatcacaa atgcagcaag tactaataaa
    31861 gagcctgtta agcccgcaaa tatgtgggct tatttttaat tactcttcat catcccgcag
    31921 gaactgacaa aaatcttcgc tccccatcat atcgacagtg tttttaaatt cgaaaaaaga
    31981 aattcctgtc atagcacaca cgcgctggat aatcagtttt ttcttttgct gtctgacggt
    32041 tgcggtttca ccaaactgga taacagccag gactgtttca tcatatgatt tcaggacaaa
    32101 atcacaggtt atattctgca cttcacggat taaatctttt acagcttcct cgctaccatg
    32161 aggacgaaca aattcaatga gccgtatttt gggaaaaacg gaataatcag gtataatatt
    32221 acgtgaaaga atgcctaaaa actctgattc attatttgag agtaagggta ctttagtaaa
    32281 acaatcaacc tccccaatgg ctgtaaaagc attggttgtc aaagctggat tgttcttaat
    32341 aaaatcagag aatacatttt cagctgatgg caaaacaaca gcagaattat gttgttcatc
    32401 tcgtttttta ttacggttaa atatcatttc atattccttt taaaagagcc tgcggcaggc
    32461 acaggcaaaa acatcgtttt tggacaatct gattcaaatg ttaacatttg acatcggatt
    32521 gtctatcctg cattgttctt tactgtctgt aagatcggcg ctcattcttc cggcgttctc
    32581 ccgataccaa aaagacggaa cgcaaaacgg ctttcgatcc accattcaaa aatctgctct
    32641 gcgcaaccac aaacagttaa ggcgatccat gcagcaagaa caacgtaact actgacatct
    32701 gcacccatgt accaggcgat agttaaaccc atcactgcga taccgcctaa aaactgcaac
    32761 aagaaacgaa atcccgcaag aatccccaat ggaataacaa caaccagata aagggaagca
    32821 gccagaaggt atctgacagg tgtcagcaga taaaagaacc tggatatttt ctttttgtca
    32881 gaataaacgg catcatttgc aacatcggtt gaatgatcat tcatgctgtc cctgattctt
    32941 tgaaaatcta cgatattatc cttcatattg ttatgacctc aattttcagg tgggtacatt
    33001 ttatcaaaca tattagtaaa ctctgagtct tccctggtat cgccctcata accaattgta
    33061 taagagaact ttaatttata aacttttctc ccaatttttt ctgaaactac gaaacttaag
    33121 ttctttactt ccgtatgttt catgatttct tttactgatt tattaagaac atctctttta
    33181 aaagcaggat aatctggata cttataatcc ttcacccccc ccgcccctat tgtataaaga
    33241 ttcaattcat ctttaagttc atctattgtc atttcaaaac tattcgcgcg agaattatta
    33301 ctatatattt tacgaatgag ttgatatagt gatgcagcat taacacttgt cagtcgaaca
    33361 acagataata aaacttgcgt tgtataacgt ttttcttcac caataagttt acataaaaat
    33421 cttttcgctt ctttcgtaaa cttgatcccc actctacctt cattcctgta ataagtagaa
    33481 aaaacagtca gactcaaatt cattgaatca ggtacattac ttttagtgaa cttaaatccc
    33541 aaatcactac tcagttctaa tatttcatca tgtttcagct taagaagcgt cgtatctaat
    33601 atattagagc catccctcaa agcaagataa gccgcatcag gcttaacctg aacccattta
    33661 atgtaatcgg caactgtcac ataaaatatg tgatcatcat cgaattcatt tttagagttt
    33721 atctggcaca tggctaaaaa taagactttt ttagcagcca taggcaatgt tgacagcgtt
    33781 gaattcaatt catttcgatg tctcactttt gttaagcgag aaagggaagt cttatttgtc
    33841 gtcattctca ttgttcca
//
