LOCUS       NZ_CP024132            35098 bp    DNA     circular CON 16-JUN-2024
DEFINITION  Escherichia coli strain 14EC007 plasmid p14EC007a, complete
            sequence.
ACCESSION   NZ_CP024132
VERSION     NZ_CP024132.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN07807399
            Assembly: GCF_002855415.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 35098)
  AUTHORS   Li,B. and Wang,X.
  TITLE     mcr-1 positive E.coli isolates in China
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 35098)
  AUTHORS   Li,B. and Wang,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-OCT-2017) Chinese Academy of Science, South China Sea
            Institute of Oceanology, 164 Xingang West Rd, Guangzhou, Guangdong
            510000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. v3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002855415.1-RS_2024_06_15
            Annotation Date                   :: 06/15/2024 02:19:46
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,343
            CDSs (total)                      :: 5,222
            Genes (coding)                    :: 4,902
            CDSs (with protein)               :: 4,902
            Genes (RNA)                       :: 121
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 90
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 320
            CDSs (without protein)            :: 320
            Pseudo Genes (ambiguous residues) :: 0 of 320
            Pseudo Genes (frameshifted)       :: 118 of 320
            Pseudo Genes (incomplete)         :: 205 of 320
            Pseudo Genes (internal stop)      :: 57 of 320
            Pseudo Genes (multiple problems)  :: 53 of 320
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP024132.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..35098
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="14EC007"
                     /isolation_source="clinical patient"
                     /db_xref="taxon:562"
                     /plasmid="p14EC007a"
                     /geo_loc_name="China"
                     /collection_date="2014"
     gene            37..552
                     /locus_tag="CR535_RS27160"
                     /old_locus_tag="CR535_27070"
     CDS             37..552
                     /locus_tag="CR535_RS27160"
                     /old_locus_tag="CR535_27070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025391.1"
                     /GO_process="GO:0006457 - protein folding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="J domain-containing protein"
                     /protein_id="WP_001025395.1"
                     /translation="MNIQEALNVFGLSGELTEKDIKAAYRKAALKYHPDRNPLGAELMK
                     AVNAAFDVLMANIDKINQFQSTDEHARYNYGDDLEKVLNVLSGLSGLVFEVIGNWVWIS
                     GETITHKETLKEIGCKWAAKKKQWFYRPDEHKSYWNREEHTIEEIRAKYGTTGQRRATG
                     WQRVETRA"
                     /name="J domain-containing protein"
     gene            657..1199
                     /locus_tag="CR535_RS27165"
                     /old_locus_tag="CR535_27075"
     CDS             657..1199
                     /locus_tag="CR535_RS27165"
                     /old_locus_tag="CR535_27075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001401654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001083906.1"
                     /translation="MNSFFEQYHPVFEVVCRILGNGWRVNKLDDCSSRIKLTSPQFKNY
                     SVHIRMEKDRFSVVGSVDSRSWRSPHHVCTLSRKRNPVDIAADIERKILVNASQEVLQA
                     IEYEKHQVEKKDEILILKGMLSQLVQLESWYGALTGFKAENGLNGKVTEQGDSYDLQIR
                     GLSIDQLVKITGYLKQL"
                     /name="hypothetical protein"
     gene            1196..1447
                     /locus_tag="CR535_RS27170"
                     /old_locus_tag="CR535_27080"
     CDS             1196..1447
                     /locus_tag="CR535_RS27170"
                     /old_locus_tag="CR535_27080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001565860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001230707.1"
                     /translation="MRKNKGDVTYFLEKEGDNYRLTKRIKARTNVKIGNKTTKITLYDA
                     VLNENELQHIDFTCAGLREDDETPVKNLIKEFMLNETR"
                     /name="hypothetical protein"
     gene            1434..1661
                     /locus_tag="CR535_RS27175"
                     /old_locus_tag="CR535_27085"
     CDS             1434..1661
                     /locus_tag="CR535_RS27175"
                     /old_locus_tag="CR535_27085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000801440.1"
                     /translation="MKPDNTPENVKKLRLKAGLTQKECSHIYGVGLRTWQKKEEVNTQN
                     SQSLSLVEFEFLLLLAGEHPEYVLCKRESK"
                     /name="hypothetical protein"
     gene            2115..2414
                     /locus_tag="CR535_RS27185"
                     /old_locus_tag="CR535_27095"
     CDS             2115..2414
                     /locus_tag="CR535_RS27185"
                     /old_locus_tag="CR535_27095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000650309.1"
                     /translation="MKCSSVFTSTTNHVFTFERVTLCTIILMHKDTGQQYVVIFTDNNK
                     IRDYKAGIVPQFGELKQSDVDLVLFYRDEYEKYFDSLKDGDECLSFKDFIECLC"
                     /name="hypothetical protein"
     gene            2505..2855
                     /locus_tag="CR535_RS27190"
                     /old_locus_tag="CR535_27100"
     CDS             2505..2855
                     /locus_tag="CR535_RS27190"
                     /old_locus_tag="CR535_27100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000854261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000854259.1"
                     /translation="MKTLKQAAMQFASDLRNNRCFKAAYNDALLELDREDLNAIVQCTF
                     LFEPKRTLAELDKLIKKIEVEEDYEFCVSLDKGKGLHEVRTFKSEREALDAYRILTLYG
                     YTVTIEKKEGND"
                     /name="hypothetical protein"
     gene            3160..3408
                     /locus_tag="CR535_RS27195"
                     /old_locus_tag="CR535_27105"
     CDS             3160..3408
                     /locus_tag="CR535_RS27195"
                     /old_locus_tag="CR535_27105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005653200.1"
                     /GO_function="GO:0003729 - mRNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family toxin"
                     /protein_id="WP_000520549.1"
                     /translation="MGKTDKLLAKFLNSKKTFEWDELVVLFSSLGYVKKEMQGSRVRFF
                     NAEINHTILMHRPHPESYIKGGTLKAIKQNLKEAGLL"
                     /name="type II toxin-antitoxin system HicA family toxin"
     gene            3405..3752
                     /locus_tag="CR535_RS27200"
                     /old_locus_tag="CR535_27110"
     CDS             3405..3752
                     /locus_tag="CR535_RS27200"
                     /old_locus_tag="CR535_27110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="WP_000681613.1"
                     /translation="MKHLKYKGYLGTVEPDFENNVLYGKLAFIRDLVTYEASTLAELEQ
                     EFKTSVDLYLQSCVEDGKEPDTPFKGVFNVRLDPELHRRVAEMAMEEDLSLNAFVNKAL
                     EKEVSNHRAGA"
                     /name="type II toxin-antitoxin system HicB family
                     antitoxin"
     gene            4113..4616
                     /gene="taxA"
                     /locus_tag="CR535_RS27210"
                     /old_locus_tag="CR535_27120"
     CDS             4113..4616
                     /gene="taxA"
                     /locus_tag="CR535_RS27210"
                     /old_locus_tag="CR535_27120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000781813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxosome-coupling protein TaxA"
                     /protein_id="WP_000781813.1"
                     /translation="MKMIAFRLSDDELKFAEHNAILSGFTSINAFAKHNVLNIETKPVN
                     IPVNNEPAKLVSVRLYPHEIELVKRNAALHGMSMSREIAIRVRQSLLKSEVCLYPDEVK
                     ELKKLSTAVDRVGRNIHFIIKGERFCTVNDPDFRKDVIEVIELCKQIDSKLETLTKSVV
                     NRFG"
                     /name="taxA"
     gene            4620..5849
                     /gene="taxC"
                     /locus_tag="CR535_RS27215"
                     /old_locus_tag="CR535_27125"
     CDS             4620..5849
                     /gene="taxC"
                     /locus_tag="CR535_RS27215"
                     /old_locus_tag="CR535_27125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001329504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA relaxase/nickase TaxC"
                     /protein_id="WP_001329504.1"
                     /translation="MGVYVEQEYRIKRAKGTGRDPKSPKLSGRHIHASKSAFNHKVRHG
                     ADKKAYTWTPTKEVTFKITGSGKTAAGIKNGIDYITRNGELEAYCYDGKGSEQTGKGED
                     FNREFTSTLSKGNDYSRTYRGENIDHVKNMVFSPPPEAGVSREDALKATVEFLKETYPN
                     HAFVAVYHDDKEDHPHVHVNIKLRDEETGRRLRLTKSETRKFRNGFHRKLKGMGYDVTA
                     TWKKDPERKREIERLQAENPKRLRNVYKVVDFGETSYQNKAGEKRTPFLTYETLKGGKQ
                     VTIWGKDLKNHFESEKLQPGTLIKVKKLAPTLVRSPMFNDDGTVAGYRETHRNNWQIEN
                     IALERNRERQVHERETRQPEESDVKKQLSRKHEQGHNIGFALEHGFTKDSEEHKKLRIQ
                     QERNWKGLGF"
                     /name="taxC"
     gene            5926..6219
                     /locus_tag="CR535_RS27220"
                     /old_locus_tag="CR535_27130"
     CDS             5926..6219
                     /locus_tag="CR535_RS27220"
                     /old_locus_tag="CR535_27130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134733.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]; GO:0016987 - sigma factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]; GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-like helix-turn-helix DNA-binding
                     protein"
                     /protein_id="WP_060598542.1"
                     /translation="MTEHDAICISGLHQIFSDEEHLSEQQKDIILMYAYGYTLNEIADF
                     KGLKPSTVRKYLDSVRAELGGVSLAGIRTLVLIRTNALLVSSLSRISERGNL"
                     /name="sigma factor-like helix-turn-helix DNA-binding
                     protein"
     gene            6216..6431
                     /locus_tag="CR535_RS27225"
                     /old_locus_tag="CR535_27135"
     CDS             6216..6431
                     /locus_tag="CR535_RS27225"
                     /old_locus_tag="CR535_27135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EexN family lipoprotein"
                     /protein_id="WP_000760375.1"
                     /translation="MKKYLLFALPFFVVGCSEEVKSVDWWGQHLTEAKQKQAECEKSGS
                     DSQNCKNVKQALFIQSQKDAPVPTFD"
                     /name="EexN family lipoprotein"
     gene            6787..7407
                     /locus_tag="CR535_RS27230"
                     /old_locus_tag="CR535_27140"
     CDS             6787..7407
                     /locus_tag="CR535_RS27230"
                     /old_locus_tag="CR535_27140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012908959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing protein"
                     /protein_id="WP_000157549.1"
                     /translation="MASLFPALLLCAASVHPDTINDIARVESGFNPYAVAEIIPERERG
                     SYGKSVISHMPKSKEEALTVIREIENRKRRYSVGLMQITSSNFSFYSTSAEKLLDSCEN
                     LSVFEKIIVDCYKRGRSLENALSCYYTGNFSNGKRKEKEFNNTSYVERIGYTGNEKKYV
                     VPGTRSNGGEQRKNRSHNASVIWPETILKSAFVDNSHPTKVIN"
                     /name="lytic transglycosylase domain-containing protein"
     gene            7421..7747
                     /locus_tag="CR535_RS27235"
                     /old_locus_tag="CR535_27145"
     CDS             7421..7747
                     /locus_tag="CR535_RS27235"
                     /old_locus_tag="CR535_27145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbC/VirB2 family protein"
                     /protein_id="WP_000008647.1"
                     /translation="MSFKKSVCNRISSSVTAVMQRKNKVVMAVAGATVASPAFADGFSK
                     AETLLEKVKTGLSGLSLVTVTIACLWVGYKVLFGGSTIRECSPIIIGAIVIASAAEVAS
                     MMVN"
                     /name="TrbC/VirB2 family protein"
     gene            7766..10513
                     /locus_tag="CR535_RS27240"
                     /old_locus_tag="CR535_27150"
     CDS             7766..10513
                     /locus_tag="CR535_RS27240"
                     /old_locus_tag="CR535_27150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231857.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB4 family type IV secretion/conjugal transfer
                     ATPase"
                     /protein_id="WP_000105985.1"
                     /translation="MSTLYKAMTRPAMYVGVPVVPLTVVAGALFLAGVYISKLIWLAIP
                     VAVFVLRMITKQDDHIFNLYFLKLKMLGNSVCNRFFGARAFLSGQYEAVEIDEFVNAMK
                     LNERITTGKYIPYSSHVDKNIVKTKNGDYVATWQLMGINFESISAEMLETIDSQVATLV
                     RSFSGLPVSFYNHSCRASFYDAFTTKSGNKYADIISDCYYGSMKKNKFKGNTLYFTLIY
                     RPDGRVEKLEKRKKSIKEKKDDINIHVKRMNEMINTFSGALDKFTCKLLGMYEENGKVF
                     SSQLSFYNYLLTGKLQKIRVTDSPVYNVLGGVDVFFNHDTGQICRIDGNKFFRSIEIKD
                     FCSETASGVFDVLQYSDADYIITHSYTSMSKSEALSTIKRAEKQLKSTEDDAVTQLQEL
                     EKAKNDIVSGDISFGYYHFTLMVMADSIRELDESVSKITADFTDLGIIPALSTMSLPAA
                     YFAQLPAVFHLRPRLSPVSNVNFVELASFHNFYQGKRDKNCWTEAVAILKTPSKQAYYL
                     NLHNSVLFKDETGEKNLANTKVIGTAGSGKTMFLSYLACSLQKYNNPETFADSAKNKKL
                     TCVFLDKDRGAELCIRMLGGEYYTVKSGEPTGWNPFALEATKRNRIFVKQLMEILCTRN
                     GERLSTRERLLISESVDAVMDFPPGEMREYGITRMLEHLMQRDDRDEQENGIILRLSQW
                     ANGQAHGWVFDNAKDTFNIQHVNNFGIDGTEFLDDPMVCAPITFYLLYRITQLLDGRRL
                     VIFLDEFWKWLQDEAFSDFVYNKLKTIRKLNGLVIPATQSPDEILKNKISRAVVEVCST
                     SIYLANPDADYNDYVEGLKLTPEEFNIVKNLDPMSRQFLIKKSSLKKGDGKSFSALATL
                     DLSGLGGYLKILSASADNLEIFESIYHEGMEPDDWVPEYLERAI"
                     /name="VirB4 family type IV secretion/conjugal transfer
                     ATPase"
     gene            10525..11241
                     /locus_tag="CR535_RS27245"
                     /old_locus_tag="CR535_27155"
     CDS             10525..11241
                     /locus_tag="CR535_RS27245"
                     /old_locus_tag="CR535_27155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_000832283.1"
                     /translation="MKRVKTLMLISLLTASFYSSAGIPVAIDASPEWAVEAARWTERLK
                     QWSETAQHYQSQIQAYKDQLATATGIRNIAAFTNELSNLQSELTNIYKQGNSYISDFTS
                     NPEGALSSQAKNLFSKYGAFDMCNTGYERNDNLCKARIVSTAASIEQGNEINKQLSSAM
                     SQIQSLSSRIEASKDIKESQDLANALQAQSLKMQAIKMQYDVWNNKNKADHEMLVTQEQ
                     EAFIKQQKEAEPLTFD"
                     /name="type IV secretion system protein"
     gene            11253..12347
                     /locus_tag="CR535_RS27250"
                     /old_locus_tag="CR535_27160"
     CDS             11253..12347
                     /locus_tag="CR535_RS27250"
                     /old_locus_tag="CR535_27160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001677777.1"
                     /GO_process="GO:0030255 - protein secretion by the type IV
                     secretion system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_000046889.1"
                     /translation="MAQGFFVKYNSTVMDSVDKISSSYQTQFANDIMSLATVSVTLYVL
                     WKGYQILASKTQTPLQDLVWDLSKFAIIIMFITNADGYLTAATDALQGMKDGFSGGVSV
                     WQTLDNLWKSTQNLGAEIYSLDKSTYVKDQGVVGQFLIWTGSLILMAVSVVVFLTADVT
                     MKLLIITAPIFIFCLMFGFIRSMFNNWLQSLFSSILTVLFASLVIRIAMDFQGMILSHA
                     IRAAQTGNVNLVSTGAMGFMAGFLGALLVLIAKGFAVQLAGAGVEGAVQGAAMMGLGAA
                     GMATGKSLMLGGRAGLGFGLGMAGRTGMNSLSGKAGNLMGRGARTAAEWAGEKGYQALA
                     PTGALGMKARRLASLEKARARNAA"
                     /name="type IV secretion system protein"
     gene            12862..13548
                     /locus_tag="CR535_RS27270"
                     /old_locus_tag="CR535_27180"
     CDS             12862..13548
                     /locus_tag="CR535_RS27270"
                     /old_locus_tag="CR535_27180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="WP_001290765.1"
                     /translation="MSEKIEKKIETAKSFERQLYAENERSKKNAWRVAVAASLLSLCLG
                     AAICVLVPLKEKELAIVAVGEKTGRTELITQVKQEKILQSEALGRYFVNTYITLREGYN
                     YPSLQYDYETVQLYSSNTVKDDYLRLYNSDMAPDKIYHNNGSYVAVEVISNIISDATAP
                     DKLASVRFKKTTRNFTTGQVSVSYWTARVTYRFEPEKSVKSSSRELNPLGFTVTSYQTD
                     REVRGE"
                     /name="type IV secretion system protein"
     gene            13545..14453
                     /gene="virB9"
                     /locus_tag="CR535_RS27275"
                     /old_locus_tag="CR535_27185"
     CDS             13545..14453
                     /gene="virB9"
                     /locus_tag="CR535_RS27275"
                     /old_locus_tag="CR535_27185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001299943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type conjugative transfer protein VirB9"
                     /protein_id="WP_001329500.1"
                     /translation="MMKKLFIATCLLLPGLVYSAATPLPSGFDARMQTVSYNGANTTVI
                     RSKTGFLTSVVFDEGEAVISAKAGFPAGWEITTDDNVVYINPRPVVQEQEGDEGEKLKK
                     VFQPTEKEWDTNLFVRTTKRIYSLDLILLSEEKQAQPAYVVQFRYPSEIAKKNAEEVRL
                     AKEKQEKLRQKKLISESFEKADAPKNWNYFMRVNEKYDSRRIAPDFAYDNGIFTFLGFN
                     SGKVFPAPFAVRDGQEQTLAFNVETKGKYKIMVIHNVNDKFVLRYGNSVVGVVNKSFGK
                     VLTDQRNTSSPAVERVEVNND"
                     /name="virB9"
     gene            14446..15564
                     /gene="virB10"
                     /locus_tag="CR535_RS27280"
                     /old_locus_tag="CR535_27190"
     CDS             14446..15564
                     /gene="virB10"
                     /locus_tag="CR535_RS27280"
                     /old_locus_tag="CR535_27190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB10/TraB/TrbI family type IV secretion system
                     protein"
                     /protein_id="WP_000131271.1"
                     /translation="MTDMKKTDDLVDDANQSKLESKPVHDIGDIRNKNNRMRSGFLFGL
                     MAVLVIGIFALKTYKNYFADDQQKASESTGDTSISQVSKIRTGLGQNFDPVENKAIINP
                     GATGSGNTVSDGHKEVPQEGFRKYLSIPVAGQGGSQTGASGSSRTSQTSEPQEERKESK
                     ENVPGKSGMKVTAINLDPDLYIEENRLIPCALTTRFVSDVAGRISCVFTEDVWSANHHT
                     KLLEQGTKAFGRYQTGTLNHGQGRMFVMWEQLRTPDNKRIDMVNTAAAGPLGEAGIDGW
                     IDSHFWERFGGSLMLSMVQDVAAAAADNAPGKDRNVDYTENSRQAMAEMAKVALENSIN
                     IPPTMYKNQGDIITIMVGEDIDFSDIYELKVK"
                     /name="virB10"
     gene            15566..16594
                     /gene="virB11"
                     /locus_tag="CR535_RS27285"
                     /old_locus_tag="CR535_27195"
     CDS             15566..16594
                     /gene="virB11"
                     /locus_tag="CR535_RS27285"
                     /old_locus_tag="CR535_27195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001401678.1"
                     /GO_component="GO:0043684 - type IV secretion system
                     complex [Evidence IEA]"
                     /GO_process="GO:0044097 - secretion by the type IV
                     secretion system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type DNA transfer ATPase VirB11"
                     /protein_id="WP_000017226.1"
                     /translation="MSGVIPVSISNKSLDFYKNQVFQSFLDIEGLTEIAVNRPGEIWTE
                     INGDWTFHNNDSVTFDFCKRFSHTLASFRGDEIGETKPLLSATLESGERVQVVFPPACE
                     RNTISITIRKPSTRQITHKEYVANGFYDYVQSGKKHRTYDDELLDLFRARNIAAFMELA
                     VAAGKTIVFAGATGSGKTTYMKSLIDFIPLNTRLITIEDAEEIKFFIHKNYVHLFYPSE
                     SGSDSGSIITAAKLIKSCLRMKPDRILLAEIKGGDAWDFVKVAGSGHSGSMTSIHAASA
                     KDAIIQMVTKCYQNRECQNLPFDVLRKIIMDSIDIVVHVGRDGVVRHMSDIYYKGAECE
                     NF"
                     /name="virB11"
     gene            16581..18443
                     /gene="taxB"
                     /locus_tag="CR535_RS27290"
                     /old_locus_tag="CR535_27200"
     CDS             16581..18443
                     /gene="taxB"
                     /locus_tag="CR535_RS27290"
                     /old_locus_tag="CR535_27200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxosome-coupling protein TaxB"
                     /protein_id="WP_170324155.1"
                     /translation="MKTFNKSQSVFIFAVMLVAAWFAGSFIFFVLYFSQIKNLKPLKAV
                     FRSIDAYRMDIFTDSLTLSVVTTDIRVLAFVALGAGFVVSLIIPVAALIKLNEKKENIF
                     GDARFATINDIRESNSFTLDGDEKDGIIVGIKDKKIIRYVGAAFSAMGAGTRAGKGAGI
                     VITNLMKYWWSVIILDPKRECFNITSLIRKVILGHEVYKFDPFSSVTHRFNPLYYVSMG
                     TSEGFNQLENLSLIIYPYKTDGADAGSYLNKTAGGVFKSYAVALWFMIKNDKAGLKTLD
                     IEPVFSMSKINQLFERAEPEHLLSFMNDIRSELRGKDKTLADIGVAGLKAFIEMEDKTK
                     AQLKSNFLNGLSPFANPNVANATDGNDFDLRQVRKKRMTIYFCISGDNARLAEKITNIF
                     FQLAIQVNLEKMPTDDPEIKHDCLFLLDEFPSIGAVDYIKSKSGLIAGYKLKLLIVYQV
                     GSQLEEIYSYAGSKTLLASAPCKIVYSASDVKDARELSEAMGTRTVTIGSKSKSRSRGG
                     TSRSESESLIERPLVTTNELLTLKFSEEILAMKGENPIRCEKAFYYLNEYFFGDFVKVA
                     PELANIFPRKKGKLVMPPQKVFENEIVAKGYLVVKDVPDLDKAA"
                     /name="taxB"
     gene            18452..18874
                     /locus_tag="CR535_RS27295"
                     /old_locus_tag="CR535_27205"
     CDS             18452..18874
                     /locus_tag="CR535_RS27295"
                     /old_locus_tag="CR535_27205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001353737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cag pathogenicity island Cag12 family protein"
                     /protein_id="WP_015059903.1"
                     /translation="MMKKLVFLLISILAGCSSPPEPTPVQFEKANEVINPSLPYVPDFH
                     GVIKSDVSGKGWVYEITSLSGVQARTPTFYYALAHADRIVVTTHDAGLWFRIRDLLKME
                     GATAVVEWRNEKSFLPEQVKIVFIKAQNEVKNDWKK"
                     /name="cag pathogenicity island Cag12 family protein"
     gene            18858..19163
                     /locus_tag="CR535_RS27300"
                     /old_locus_tag="CR535_27210"
     CDS             18858..19163
                     /locus_tag="CR535_RS27300"
                     /old_locus_tag="CR535_27210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001350475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbM/KikA/MpfK family conjugal transfer protein"
                     /protein_id="WP_001350475.1"
                     /translation="MTGKNRVVLPALLALGLISTNANASDPCASVLCLYGKAVGQGGGS
                     ECRSAEKDFFNILKKKKGSIRWSKTFDARKAFLNQCSTADPAAISKIMSKFGRVRG"
                     /name="TrbM/KikA/MpfK family conjugal transfer protein"
     gene            <19276..19470
                     /locus_tag="CR535_RS29025"
                     /pseudo=""
     CDS             <19276..19470
                     /locus_tag="CR535_RS29025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517490.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /name="ATP-binding protein"
     gene            19474..20046
                     /locus_tag="CR535_RS27305"
                     /old_locus_tag="CR535_27215"
     CDS             19474..20046
                     /locus_tag="CR535_RS27305"
                     /old_locus_tag="CR535_27215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012908955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001198960.1"
                     /translation="MQYALFDGFERKFLLDALEFGVLKDWKENPVKELPDIDESAHPFH
                     ICYGGYLLNPGVSDSDISRKIKDQAGFWLAAIDDTRMDCHSIAYYDIHTLPLISCGHQK
                     IVPFAALIKADECIISKIASYSGFAVTAFLRIKEWDIATNILNREGIFAFNGCERRFRV
                     VSKDNWQHTVSEERAIRCAKRLIQCKG"
                     /name="hypothetical protein"
     gene            20051..22204
                     /locus_tag="CR535_RS27310"
                     /old_locus_tag="CR535_27220"
     CDS             20051..22204
                     /locus_tag="CR535_RS27310"
                     /old_locus_tag="CR535_27220"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247728.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003916 - DNA topoisomerase activity [Evidence IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="WP_001235745.1"
                     /translation="MRLFIAEKPAVANDIVKALGGNFTRHDGWFESDNAIVTNCFGHII
                     ESQPPENYNPEYKAWKVETLPLRLYPVKYQPVESAAKQVKTILELIRRGDVTEIVHAGD
                     PDDEGQLLVDEVLEYAGNTKPVKRVLINDNTLPAVKKALANLKDNRDFKGLYLKALARS
                     VADAVYGFSMTRAYTIPAKARGYQGVLSVGRVQTPVLGLIVNRTRANQNHKSSFYYTMT
                     GVFQRGADVIRANWKPGEFAPLTDRKLLDKAWADGTAASLAGKPATVEAAATDDKKTAA
                     PLPFNLVRLQQYMNKKFKMTAQKTLDITQQLREKYKAITYNRSDCSYLSDEQFSEAPQV
                     IDALKSVFPQSLDIDSARKSKAFNSAKVTAHTAIIPTASVPDVNALSTDERNVYLAIAQ
                     HYLVQFMPEKAYQEVSVAIQCGDESFYARARKTTDSGFEAFLGAETTDEGESEDNDDSA
                     FELLCKIRTGETLTTKEVIVNEKKTTPPPLFTEASLLAALVRVADFVTDPTIKKLLKDK
                     DKDKKDEHGGIGTPATRAAILETLKKRNYITLEKGKLIPTDTGYALIDALPGIAVNPDM
                     TALWSEKQAAIENGDLTVEQFINDLYGELTGMISDVDLGEMKIEPAAPAGQFQRLDSPC
                     PSCGKHIVIRPKGYFCTGCEFKIWSEFSGKKITQAQAEKLVKSGKTDLIKGFKKKSGGT
                     YDTVLVLEDKKTGKLGFPARAKK"
                     /name="type IA DNA topoisomerase"
     gene            22201..22407
                     /gene="hha"
                     /locus_tag="CR535_RS27315"
                     /old_locus_tag="CR535_27225"
     CDS             22201..22407
                     /gene="hha"
                     /locus_tag="CR535_RS27315"
                     /old_locus_tag="CR535_27225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin expression modulator Hha"
                     /protein_id="WP_000850859.1"
                     /translation="MKTKQEWLFQLRKCTSRDTLEKVIEINRYKLPLSESEAFYSAADH
                     RRAELVMNKLYDKVPSGVWKYVH"
                     /name="hha"
     gene            22425..22889
                     /locus_tag="CR535_RS27320"
                     /old_locus_tag="CR535_27230"
     CDS             22425..22889
                     /locus_tag="CR535_RS27320"
                     /old_locus_tag="CR535_27230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293133.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0030527 - structural constituent of chromatin [Evidence
                     IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="H-NS family nucleoid-associated regulatory
                     protein"
                     /protein_id="WP_001293134.1"
                     /translation="MSELTKEDEYGIISRTMMNIRSLRVFAREIDFEQLLEMQEKLNVV
                     IEERREDAEREAAERQELEAKRQQAIEYIISLGLDPESLLAPVTADTVKTRRKAKGGVR
                     KAKYRFKDENGEIREWSGNGKRPLALQKLLDEGHFMEDFLIEKTKPEQAE"
                     /name="H-NS family nucleoid-associated regulatory protein"
     gene            22976..23680
                     /locus_tag="CR535_RS27325"
                     /old_locus_tag="CR535_27235"
     CDS             22976..23680
                     /locus_tag="CR535_RS27325"
                     /old_locus_tag="CR535_27235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_001067855.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            24463..24558
                     /gene="dqlB"
                     /locus_tag="CR535_RS29630"
     CDS             24463..24558
                     /gene="dqlB"
                     /locus_tag="CR535_RS29630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DinQ-like type I toxin DqlB"
                     /protein_id="WP_021534057.1"
                     /translation="MINMLIIVLRAVVAVANALIAVLELIRQFID"
                     /name="dqlB"
     gene            25221..25868
                     /locus_tag="CR535_RS27345"
                     /old_locus_tag="CR535_27255"
     CDS             25221..25868
                     /locus_tag="CR535_RS27345"
                     /old_locus_tag="CR535_27255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001694199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division plane positioning ATPase MipZ"
                     /protein_id="WP_000587671.1"
                     /translation="MIIVIGGDKGGTGKSHLATNLTVCLSQQGKRTGLVETDLNGSTKK
                     WNKRREQAGLPPVALNEAYGDISAKITKMADVAEILIIDTAGYDSTEFRTALKVADIVI
                     VPIDPLAQVEADSLQTVTKIVRDAQKINPRLAAHVLLYKCQPNTFSEQQELRDSLNSHD
                     YWLKPMKSTVSFLRAFVRAMNQGMGVHELKSNVSGASQAKAQIELLLKELEL"
                     /name="division plane positioning ATPase MipZ"
     gene            25943..26212
                     /locus_tag="CR535_RS27350"
                     /old_locus_tag="CR535_27260"
     CDS             25943..26212
                     /locus_tag="CR535_RS27350"
                     /old_locus_tag="CR535_27260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001086090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001086090.1"
                     /translation="MAKLELPELEQNQEVNATKFVQDAGKRPTENKTKLASFRIPNELL
                     EFIDNESKRLHRPKTKIIKAALLAYQDLDENELINLWFRADRND"
                     /name="hypothetical protein"
     gene            26373..27002
                     /locus_tag="CR535_RS27360"
                     /old_locus_tag="CR535_27270"
     CDS             26373..27002
                     /locus_tag="CR535_RS27360"
                     /old_locus_tag="CR535_27270"
                     /inference="COORDINATES: protein motif:HMM:NF022440.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2806 domain-containing protein"
                     /protein_id="WP_223424520.1"
                     /translation="MSLIDLSLSGLSEPGTKLIEKISDAIGVLYEPTRIRKKAKAEAEA
                     KRTELISRLELEGIEKRAVERFLKRETKRQENIENITMQAAQSLSESDNVSDIDEDWIE
                     AFFRECEDISDEQMQMLWGRILSEEAKSKGSFSRRTLKLLSTISKEEANLITYFGKFVW
                     QANKLTPILFTDENGDTEGITFDKLSVLDSLGVIQQGIGYSLRYKL"
                     /name="DUF2806 domain-containing protein"
     gene            27176..28801
                     /locus_tag="CR535_RS27365"
                     /old_locus_tag="CR535_27275"
     CDS             27176..28801
                     /locus_tag="CR535_RS27365"
                     /old_locus_tag="CR535_27275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_049589868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine--lipid A transferase MCR-1.1"
                     /protein_id="WP_049589868.1"
                     /translation="MMQHTSVWYRRSVSPFVLVASVAVFLTATANLTFFDKISQTYPIA
                     DNLGFVLTIAVVLFGAMLLITTLLSSYRYVLKPVLILLLIMGAVTSYFTDTYGTVYDTT
                     MLQNALQTDQAETKDLLNAAFIMRIIGLGVLPSLLVAFVKVDYPTWGKGLMRRLGLIVA
                     SLALILLPVVAFSSHYASFFRVHKPLRSYVNPIMPIYSVGKLASIEYKKASAPKDTIYH
                     AKDAVQATKPDMRKPRLVVFVVGETARADHVSFNGYERDTFPQLAKIDGVTNFSNVTSC
                     GTSTAYSVPCMFSYLGADEYDVDTAKYQENVLDTLDRLGVSILWRDNNSDSKGVMDKLP
                     KAQFADYKSATNNAICNTNPYNECRDVGMLVGLDDFVAANNGKDMLIMLHQMGNHGPAY
                     FKRYDEKFAKFTPVCEGNELAKCEHQSLINAYDNALLATDDFIAQSIQWLQTHSNAYDV
                     SMLYVSDHGESLGENGVYLHGMPNAFAPKEQRSVPAFFWTDKQTGITPMATDTVLTHDA
                     ITPTLLKLFDVTADKVKDRTAFIR"
                     /name="phosphoethanolamine--lipid A transferase MCR-1.1"
     gene            28873..29595
                     /locus_tag="CR535_RS27370"
                     /old_locus_tag="CR535_27280"
     CDS             28873..29595
                     /locus_tag="CR535_RS27370"
                     /old_locus_tag="CR535_27280"
                     /inference="COORDINATES: protein motif:HMM:NF028536.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAP2 family protein"
                     /protein_id="WP_039003037.1"
                     /translation="MPYLSNKRLLAEMSIALVMAIVATLTLEHSQIDLMVADWFYLGMG
                     HWMVAKQAFLPDLLLYSGLKKLLMAMLIYLLVATICRAYHEKKGNAITAKWLVPVTKFR
                     VRELAYLVLTLILVPTVVASLKAYTHVVCPVHLTIFDGTLPYLPMLDSMRNTIPDKCFP
                     AAHASSGFALFAFAFAPSLRRRRGAIIIVVMALGWAMGCYKMIIGDHFLSHTVVSMMLA
                     WAMSAGLAWVFFKKGEQV"
                     /name="PAP2 family protein"
     gene            complement(29986..30513)
                     /locus_tag="CR535_RS27380"
                     /old_locus_tag="CR535_27290"
     CDS             complement(29986..30513)
                     /locus_tag="CR535_RS27380"
                     /old_locus_tag="CR535_27290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001473365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2726 domain-containing protein"
                     /protein_id="WP_000577043.1"
                     /translation="MIFNRNKKRDEQHNSAVVLPSAENVFSDFIKNNPALTTNAFTAIG
                     EVDCFTKVPLLSNNESEFLGILSRNIIPDYSVFPKIRLIEFVRPHGSEEAVKDLIREVQ
                     NITCDFVLKSYDETVLAVIQFGETATVRQQKKKLIIQRVCAMTGISFFEFKNTVDMMGS
                     EDFCQFLRDDEE"
                     /name="DUF2726 domain-containing protein"
     gene            complement(30648..31052)
                     /locus_tag="CR535_RS27385"
                     /old_locus_tag="CR535_27295"
     CDS             complement(30648..31052)
                     /locus_tag="CR535_RS27385"
                     /old_locus_tag="CR535_27295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012421203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_012421203.1"
                     /translation="MKDNIVDFQRIRDSMNDHSTDVANDAVYSDKKKISRFFYLLTPVR
                     YLLAASLYLVVVIPLGILAGFRFLLQFLGGIAVMGLTIAWYMGADVSSYVVLAAWIALT
                     VCGCAEQIFEWWIESRFAFRLFGIGRTPEE"
                     /name="hypothetical protein"
     gene            complement(31065..31328)
                     /locus_tag="CR535_RS29460"
     CDS             complement(31065..31328)
                     /locus_tag="CR535_RS29460"
                     /inference="COORDINATES: protein motif:HMM:NF044726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="WP_249824082.1"
                     /translation="MESLYNRAGGEDYKYPDYPAFKRDVLNKSVKEIMKHTEVKNLSFV
                     VSEKIGRKVYKLKFSYTIGYEGDTREDSEFTNMFDKMYPPEN"
                     /name="RepB family plasmid replication initiator protein"
     gene            complement(31238..31843)
                     /locus_tag="CR535_RS27390"
                     /old_locus_tag="CR535_27300"
     CDS             complement(31238..31843)
                     /locus_tag="CR535_RS27390"
                     /old_locus_tag="CR535_27300"
                     /inference="COORDINATES: protein motif:HMM:NF013235.4"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_249824081.1"
                     /translation="MAAKKVLFLAMCQINSKNEFDDDHIFYVTVADYIKWVQVKPDAAY
                     LALRDGSNILDTTLLKLKHDEILELSSDLGFKFTKSNVPDSMNLSLTVFSTYYRNEGRV
                     GIKFTKEAKRFLCKLIGEEKRYTTQVLLSVVRLTSVNAASLYQLIRKIYSNNSRANSFE
                     MTIDELKDELNLYTIGRGVKIISIQIILLLKEMFLINQ"
                     /name="replication initiation protein"
     gene            33341..33853
                     /locus_tag="CR535_RS27400"
                     /old_locus_tag="CR535_27310"
                     /pseudo=""
     CDS             33341..33853
                     /locus_tag="CR535_RS27400"
                     /old_locus_tag="CR535_27310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025391.1"
                     /GO_process="GO:0006457 - protein folding [Evidence IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="J domain-containing protein"
                     /name="J domain-containing protein"
     gene            34007..34496
                     /locus_tag="CR535_RS27405"
                     /old_locus_tag="CR535_27315"
                     /pseudo=""
     CDS             34007..34496
                     /locus_tag="CR535_RS27405"
                     /old_locus_tag="CR535_27315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001401654.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            34493..34735
                     /locus_tag="CR535_RS27410"
                     /old_locus_tag="CR535_27320"
     CDS             34493..34735
                     /locus_tag="CR535_RS27410"
                     /old_locus_tag="CR535_27320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001230706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_101973079.1"
                     /translation="MRKNKGDVTYFLEKEGDNYRLTKRIKARTNVKIGNKTTKITLYDA
                     VLNENELQHIDFTCAGLREDDETPVKNLIKEFMLK"
                     /name="hypothetical protein"
     gene            34732..34958
                     /locus_tag="CR535_RS27415"
                     /old_locus_tag="CR535_27325"
                     /pseudo=""
     CDS             34732..34958
                     /locus_tag="CR535_RS27415"
                     /old_locus_tag="CR535_27325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /name="XRE family transcriptional regulator"
     ARG             27177..28798
                     /name="mcr-1.1"
                     /gene="mcr-1.1"
                     /gene_name="phosphoethanolamine--lipid A transferase
                     MCR-1.1"
                     /tool="amrfinderplus"
                     /drug_class="COLISTIN"
                     /identity="100.0"
                     /coverage="100.0"
     Typing          complement(31066..31933)
                     /name="IncX4"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.542"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          4621..5846
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="99.511"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          11254..12320
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.719"
                     /coverage="99.0"
                     /evalue="2.6999999999999997e-172"
     Typing          12863..13545
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="1.4399999999999998e-137"
     Typing          13546..14450
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="99.669"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          16582..18440
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="98.71"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 tctcacaata gcccagcagg gcaggagatt aaaaaaatga atatccagga agcattaaac
       61 gtttttggat tatccggcga attaactgaa aaagatatca aagcagcata cagaaaagcc
      121 gctttaaaat atcatccaga tcgtaacccg ttaggggctg aactgatgaa agcggtaaat
      181 gcagcttttg atgtattgat ggcaaatatt gataaaataa atcagttcca gagcactgat
      241 gaacatgcac gatataatta cggtgatgac ctggaaaaag tattaaacgt tctttctggt
      301 ttatctggtc tggtatttga agtgataggt aactgggtct ggattagtgg agaaaccatt
      361 acacataagg aaactttaaa agaaatcggg tgtaaatggg cggcaaagaa aaaacaatgg
      421 ttttatcgtc cagacgaaca taaaagttac tggaatcgtg aagaacacac gatagaagaa
      481 atccgcgcaa aatacggtac aaccggacag cgcagggcga cagggtggca acgcgtggaa
      541 accagagcgt aaccagaacg ggggcgagaa gcccccgata ttatagccag cccgtctttt
      601 ggggcatcga acccaaaaag acgggaacag cagccacgta gcaaaaaggg aaacagatga
      661 actctttttt tgaacaatat caccctgtct ttgaagttgt ctgccgtatc ctggggaacg
      721 gctggcgcgt gaacaaactt gatgattgtt cgtctcgtat aaaactgacg tcaccgcagt
      781 ttaaaaatta ctctgtgcat attcggatgg aaaaagaccg cttttctgtg gtggggagtg
      841 tggatagtcg ttcctggcgt agtccgcatc atgtttgcac gttatccaga aaacggaatc
      901 ccgttgatat tgcagccgat atcgagcgaa aaattctggt aaatgcttcg caggaggtgt
      961 tacaggcgat tgagtatgag aaacaccagg tggaaaaaaa ggacgaaatt ctgatcctga
     1021 aaggtatgtt atcgcaactt gtccagcttg aaagctggta tggggcattg acaggcttta
     1081 aagctgaaaa cggattgaac ggtaaagtca ccgaacaggg cgacagttat gatttacaga
     1141 ttcggggctt gagtatagat caacttgtta aaattacagg gtatttgaaa cagttatgag
     1201 aaaaaataaa ggtgatgtga cttattttct tgaaaaagaa ggtgacaatt acaggcttac
     1261 aaaaaggata aaagccagaa caaatgttaa aatcgggaac aaaactacga aaattacatt
     1321 gtatgatgct gtactgaatg agaatgaatt acaacatatt gattttacgt gtgccggatt
     1381 aagggaagac gatgagacgc cagttaagaa tttaattaag gagtttatgt taaatgaaac
     1441 ccgataatac acctgaaaat gtaaaaaaat tacgtttaaa agcaggatta acacaaaagg
     1501 aatgcagtca tatttatggt gttgggctaa gaacctggca gaaaaaagag gaagttaata
     1561 ctcaaaacag tcaaagtctg tcactggttg agtttgagtt tcttttgtta cttgcaggag
     1621 aacatcctga atacgtgctc tgcaaaaggg agtcaaaata aaatgacctg tgatggtttt
     1681 atattagtac ctggagttgc gctcgtagct cgctgacgct cacacgcgca gtacagcgcc
     1741 ccgccatgct gcaatgcacc agggcggggt aaactcgctt gcgctcgcgc taactgcggc
     1801 attctgcggc gcaaatcagc ataatcatgg cctgctggtc agttgggctt tgcagggtga
     1861 agggatggcc tgtgcaccct ggtacgttcg tcagcggctg cgccgcgctt cggggcgatg
     1921 tggctcctgt gctgccctgg tattttcgtt cgccccttcc atccgcttac gcggattaaa
     1981 aaacgtgata acaatcactt atcgagtaaa aaaacgggag aaaacttgca aatacgactt
     2041 aaaggtcgta ttattgtttc atcgaaaggg gaatggcccc tctcacaata gcccagcagg
     2101 gcaggagatt taaaatgaaa tgctcatctg tttttacttc aaccactaat catgttttca
     2161 cattcgaacg agtaacgctt tgcactatta tccttatgca taaggatact ggacaacagt
     2221 atgttgtcat atttactgat aacaataaaa ttcgtgacta taaagccgga attgttcctc
     2281 agtttggcga acttaagcag agtgatgttg atttagtcct tttctacagg gacgaatatg
     2341 aaaaatattt tgattcatta aaagatggcg atgaatgctt gagttttaaa gattttattg
     2401 agtgtctttg ttaagcatta tgaatgcagg ggcatccctg cattttctgg aaatttcaat
     2461 attgattctg aaattgtcta ttaacatcaa tgcaagggaa attcatgaaa acgttaaaac
     2521 aagccgcaat gcagtttgca tctgatctgc gtaataatcg ctgttttaaa gctgcttata
     2581 atgatgctct gttagagctt gatcgggaag atttaaacgc cattgtacaa tgcacatttc
     2641 tttttgagcc aaaacgaaca ttagccgaac ttgataaatt aattaaaaag atagaagtag
     2701 aagaagatta tgagttttgt gtatcccttg ataaaggtaa aggattacac gaagtcagaa
     2761 catttaaaag tgagcgtgag gcgttggatg cttatcgcat tttgactctt tacggataca
     2821 cagtaactat agaaaagaag gagggtaatg actgactatt caaggtgtga tcaggttgtt
     2881 ccaccaacct gatcacgtta tcgacaatca aaactgaatg aggtttttaa atgtcaacgc
     2941 ggcagatcgt acagcttgct gattcccttg tcaaaggctg ggaaaccaga attccggcaa
     3001 tgaaatttag cgaatgggat caattccggt ggtggttaaa ctacttgcaa gggtatgaaa
     3061 tgttttaaat aaaaaaaggg gctttctgcc cctttgtatt ttttgacaaa aatgccatgt
     3121 gtaactataa ttagttgcat atctataggg gatggattta tggggaaaac agataagcta
     3181 ctggcaaagt ttttaaacag taaaaaaacg tttgaatggg atgaactggt cgttttgttt
     3241 tcctctttgg gatatgtcaa aaaggaaatg caggggtcaa gagtgcggtt tttcaatgct
     3301 gaaatcaatc acaccatatt aatgcatcgt ccacatccgg aaagttatat caaaggtggt
     3361 acgctgaaag caattaaaca gaatctgaaa gaggctggat tattatgaaa catttaaaat
     3421 ataaaggata tttaggcacg gttgaacccg attttgaaaa taatgtcctg tatggaaaac
     3481 tggcgtttat tcgggacctg gtaacttatg aggcttctac attagctgaa ctggaacagg
     3541 agtttaaaac atctgttgat ctgtatttac agtcttgtgt ggaggatgga aaggaacctg
     3601 ataccccgtt taaaggcgtg tttaacgtca ggcttgatcc agaactgcat cgtcgggtag
     3661 cagaaatggc gatggaagaa gatttatcgt tgaatgcctt tgttaataag gctctggaaa
     3721 aagaagtcag caatcatcgc gcaggggctt aattgccctt gtttttatgc cctgtaaggg
     3781 catgggaggc gctttgcgcc ggaagccccg cagcgcagcg aggacttaaa aagcgttacg
     3841 gcttcagccg taacaattcc cagccctgcc aggcctgttt tttctttcac aaatctttca
     3901 gctatacgtt tgcctgatgg tcgaagacga aagaatcttt cagcaacgaa atctggacat
     3961 atgcagcgac gattttatag ccaggcacag tgccacatat ggtacaatca atgcaggata
     4021 gacaatccga tgtcaaatgt taacatttga atcagattgt ccaaaaacga tgtttttgcc
     4081 tgtgcctgcc gcaggctctg ttggggtgac ttatgaagat gatagcgttc aggctaagtg
     4141 atgatgagtt aaaatttgca gaacataacg ctattttaag tggatttacc agtatcaatg
     4201 cttttgctaa gcataacgtg cttaatattg aaaccaagcc tgttaacatc ccagttaata
     4261 atgaaccagc aaagctggta tcagtgcgtc tttaccctca tgaaatagaa cttgttaaac
     4321 gtaatgctgc tcttcacggc atgagcatga gcagagaaat tgctattcgt gtgcgtcagt
     4381 ctttgttaaa gagtgaagtc tgtctttacc ctgatgaagt taaggaactt aaaaaactat
     4441 caactgctgt agatcgtgtt ggtcgcaaca ttcattttat cataaaaggt gaaagattct
     4501 gtacggttaa cgatccagat ttcagaaaag acgttattga agtgattgaa ctgtgtaagc
     4561 aaattgattc aaaacttgaa acgttaacca agagtgttgt taacagattt gggtgattta
     4621 tgggtgtgta tgtagaacag gaataccgta ttaaacgcgc taaagggact gggcgtgatc
     4681 cgaaatctcc taagttatcg ggaagacata tacatgccag taaatcggct tttaatcata
     4741 aagtcagaca tggtgcggac aagaaagcat atacctggac acctacaaaa gaagtcactt
     4801 ttaaaatcac tggctcaggt aaaacagccg caggcatcaa aaatggtatt gattacatta
     4861 cccgtaatgg tgaacttgag gcttactgtt atgatggaaa aggttcagag caaacaggga
     4921 aaggagaaga ctttaatagg gagtttactt caactttatc taaaggaaat gattactcca
     4981 ggacatatcg tggagaaaac atcgatcatg tgaaaaacat ggtcttttca ccaccaccag
     5041 aagctggagt aagcagggaa gacgctctga aagctacggt agaatttctt aaagagactt
     5101 atccaaacca tgctttcgtt gccgtatacc atgatgataa agaagatcat cctcatgtac
     5161 atgttaatat taaacttcgt gatgaagaaa caggaagaag attaagactt actaaatctg
     5221 aaaccaggaa gttcagaaac ggttttcata gaaaactgaa aggtatggga tatgatgtta
     5281 ccgctacctg gaaaaaagat cccgaacgta aacgggagat tgagcgatta caggctgaaa
     5341 atccgaaaag actccggaat gtttacaagg tggtggattt tggggagact tcatatcaga
     5401 ataaggcagg ggaaaaacga acacctttcc tcacttatga aactttaaaa ggtggaaaac
     5461 aggttacgat ttggggtaaa gacctgaaaa atcatttcga gtctgaaaag ctccagccag
     5521 gaacgcttat caaagtaaaa aaactggctc ctacgcttgt acgtagtcca atgtttaatg
     5581 atgatggaac tgttgcaggc tacagggaaa cgcatcgcaa taactggcag attgaaaata
     5641 ttgcccttga gcggaacaga gaacgtcagg ttcatgagcg tgaaaccagg cagccggaag
     5701 agagcgacgt taaaaagcag ctatccagaa aacatgagca aggtcacaat atcgggtttg
     5761 ctcttgaaca cgggtttaca aaggattcag aagaacataa aaaactaaga atacagcaag
     5821 agaggaactg gaaaggcctg ggattttaat ttgattttgg cgcaggtgaa caaagcggct
     5881 actttgctca cctgctgatc acaacaacct acgagggagg ttatcatgac tgagcatgat
     5941 gctatctgca tttctggact tcatcaaatt tttagtgatg aagaacattt gagtgagcaa
     6001 caaaaagaca ttattctgat gtacgcttat ggctataccc tgaatgaaat tgctgatttc
     6061 aaaggactaa agccttcaac tgtcagaaaa tatctcgatt ctgtaagagc tgaactggga
     6121 ggtgtctcgt tggcagggat cagaacactg gtactcattc ggactaatgc ccttctcgtg
     6181 tcaagtcttt ccaggatcag tgagaggggg aatttatgaa aaaatatctg ctttttgctt
     6241 tgccgttctt cgttgttggt tgtagtgaag aagtaaaaag tgtggattgg tgggggcagc
     6301 atcttacgga agctaaacaa aagcaggcag agtgtgagaa gtctggctct gattctcaga
     6361 actgtaagaa tgttaaacaa gcattgttta ttcagtctca gaaggatgct ccagtcccta
     6421 cattcgatta actaatgttt caatcatact agagcgccca tatgggcgct tttttttgca
     6481 tgatcacacg aatcataata tgaccatttt gtcaatgtta tttgatcgta ttgttgagca
     6541 ttgttatttt gcgaatcatg ttcgcatcta aaacaaatcc aaaacacact tatagtggat
     6601 tgattaaatg aaggagaaat cagataagtc atcggaaaaa ggggtttatg tcactataaa
     6661 actcgatccc aggttgaatg catttatcga agagaaaacg aaaacatctt tgcttagtaa
     6721 gaggaagcaa attatttact tattaatgca gagtatgcgt attgatggat atatggagcg
     6781 ttagctatgg cgtctttatt cccagccttg ttgctgtgtg cggcgtcagt tcatccggat
     6841 acgataaatg atattgcacg ggtcgagagt ggcttcaatc cttatgctgt ggctgaaatt
     6901 attcctgaaa gggaacgcgg tagctatggc aaaagtgtta tcagtcatat gcccaaaagt
     6961 aaggaggaag ctctaacagt tatcagagaa attgaaaaca gaaaaagacg ttattctgtc
     7021 ggattgatgc agattaccag cagtaatttt tctttttatt ccacgtccgc agaaaaactc
     7081 cttgattcgt gtgaaaactt gtctgttttc gaaaagatta tcgtggattg ttataaacga
     7141 gggaggagcc tggagaatgc gcttagttgt tactatacag gaaattttag taacggtaag
     7201 cgaaaagaaa aagaatttaa taatacaagt tatgttgagc gaattggtta tacagggaac
     7261 gaaaaaaaat atgttgtacc aggtacaaga agcaacgggg gagaacagcg aaaaaatcgt
     7321 tcacacaatg cgtcagttat ctggcccgaa accattctga aatctgcttt tgttgataac
     7381 tcacatccaa caaaagttat taattaacag gacttataaa atgtcattta agaaatcagt
     7441 atgtaatcgt atcagttcat ctgtcactgc tgtaatgcag cgtaaaaata aggtagttat
     7501 ggcagtcgcc ggggcaacag ttgcatcacc ggcctttgcg gatggatttt caaaagcgga
     7561 aacactgctg gaaaaggtta aaacagggct tagtggcctt tcactggtca cggtgactat
     7621 tgcctgtctg tgggtcggct acaaggttct gtttggtgga agcacgattc gtgaatgctc
     7681 acctatcatc atcggggcaa ttgttatcgc cagtgcggct gaagttgcat caatgatggt
     7741 taactaataa agcggggacg atagtatgtc tacactttat aaagcgatga cacgccctgc
     7801 tatgtatgtg ggtgttcctg tcgtccctct tactgtggtt gcaggggcgt tatttctggc
     7861 gggggtttat atcagcaagc tgatctggct ggctattcct gtcgcggttt ttgttctcag
     7921 aatgatcact aaacaggacg accacatttt taacctttac tttcttaagc tgaaaatgct
     7981 cggaaactca gtgtgtaatc gtttttttgg cgcacgagcg ttcctctccg gacaatatga
     8041 agctgttgaa attgatgagt ttgttaatgc catgaaactg aatgagcgaa tcactactgg
     8101 taaatatata ccctattcaa gccatgttga taaaaatatt gtcaaaacaa agaacggtga
     8161 ttatgtagcg acatggcaac tgatggggat taactttgag tcaatctctg cggagatgtt
     8221 agaaactatt gactcacagg ttgccactct tgttcgttca ttttccggac tgcccgtttc
     8281 attttataac cattcatgca gggcgagttt ttatgatgcc tttaccacaa aatcaggtaa
     8341 taaatatgct gatataatat cagattgtta ctatggttcg atgaagaaaa ataaattcaa
     8401 ggggaacact ctttacttta cgctgatcta cagaccagat gggcgtgtag aaaaactgga
     8461 aaaacgcaaa aaaagtatta aagaaaagaa agatgatatt aacattcatg tgaagagaat
     8521 gaatgaaatg attaatacat tctctggcgc tcttgataaa tttacctgta aacttcttgg
     8581 tatgtatgag gagaacggaa aggtattttc ttctcaactg tcattctata attatcttct
     8641 gacagggaag ttgcaaaaaa tcagagtcac tgattctccg gtgtataacg ttcttggtgg
     8701 agtggatgta ttttttaatc atgataccgg acagatatgc cgcattgatg gaaataaatt
     8761 ctttcgttct attgaaatta aagatttctg tagtgagact gcatccggtg tttttgatgt
     8821 gctccagtat tctgatgctg actatattat tacgcattca tatacatcca tgagcaaatc
     8881 agaagcattg agtaccatta aacgtgcgga aaaacagtta aagagtacag aagatgatgc
     8941 ggttactcaa ttgcaggaac tggaaaaggc aaaaaatgat attgtgtccg gtgatatatc
     9001 ctttggttac taccatttca cgctaatggt aatggcggac agtatcaggg agcttgacga
     9061 atctgtaagt aaaattacgg cagactttac tgacctgggc attattccgg cattgtcaac
     9121 catgtcattg ccagcggcat attttgccca acttccggcg gtttttcatt taaggccgcg
     9181 tttatctccg gtatcgaatg taaattttgt tgaactggca tcattccata atttctacca
     9241 ggggaaacgc gataaaaact gctggacaga agcggttgct attctcaaaa caccaagcaa
     9301 acaggcgtat tatctgaatt tacataactc agtactgttt aaagatgaaa caggtgaaaa
     9361 gaatcttgct aatactaaag ttataggaac ggcgggttca ggtaagacaa tgtttctgtc
     9421 atatcttgcc tgttcattac agaaatacaa taaccccgaa acttttgctg attctgcaaa
     9481 aaataagaag ttaacgtgtg tctttcttga taaggacaga ggggctgaat tatgtatccg
     9541 aatgcttggt ggggaatatt acaccgtaaa aagcggtgag ccgacaggat ggaatccttt
     9601 tgctctggag gcaacaaaac gtaaccgtat ttttgtcaag caactgatgg agattctgtg
     9661 taccagaaat ggtgaaagat tatcgacaag agaaagattg cttattagcg aaagtgttga
     9721 tgctgtgatg gattttcctc ctggcgaaat gcgggaatat ggcattacca gaatgcttga
     9781 gcatcttatg cagagagatg atcgggatga gcaggagaac gggattatcc ttcgtttgtc
     9841 ccaatgggct aatggtcagg ctcatggctg ggtttttgat aatgctaaag acacattcaa
     9901 tattcagcat gtcaataatt ttggcattga tggcaccgag tttcttgatg atccgatggt
     9961 atgtgcacca attactttct atctgctgta tcgcattacg cagcttctgg acggtcggcg
    10021 tcttgttatc ttcctggatg agttctggaa atggctacag gatgaagcat tcagcgactt
    10081 tgtctataac aagctgaaaa caattcgtaa gctgaacggg ctggttattc cggcaactca
    10141 gtctccggat gaaatactga agaataagat ttcacgggct gtggttgaag tatgcagcac
    10201 cagtatttat ctggctaacc ctgatgccga ttacaatgat tatgtggaag ggcttaagct
    10261 gacaccagaa gaatttaata ttgttaaaaa tcttgatcca atgtcgagac agttcctgat
    10321 taaaaaaagc agtcttaaaa agggggatgg taaatcattt tcagcacttg cgacactcga
    10381 tttatcggga cttggtggat atctgaaaat attgtctgcc agtgcagata atctggaaat
    10441 ttttgaaagt atttatcatg aaggaatgga gcctgatgac tgggttcctg aatatctcga
    10501 acgggcaatc tgacaggtga atttatgaaa cgtgtaaaaa cattgatgct gatatcatta
    10561 ttgacggctt cattttatag tagcgcagga attccggttg ctattgatgc cagtccggaa
    10621 tgggctgttg aagccgcaag atggacagaa cgactcaaac aatggtccga aactgcgcaa
    10681 cattatcaga gtcagattca ggcatataaa gaccagttag ccacggcaac aggtataagg
    10741 aatattgcgg cattcacaaa tgaactaagt aatctacaat cagaactgac aaatatttat
    10801 aagcagggga acagttatat ttctgatttt accagtaatc ccgaaggtgc attgagcagc
    10861 caggctaaaa atctgttcag caagtatgga gccttcgata tgtgtaatac gggctatgaa
    10921 cgtaatgata atctctgtaa agcacggatt gtgtcaacgg ctgccagtat tgaacaggga
    10981 aatgagatca ataagcagtt atcaagtgca atgtctcaga ttcagagttt aagtagccga
    11041 attgaggctt caaaggatat caaagaatcc caggatttgg ctaacgcatt acaggcgcag
    11101 tcgttaaaaa tgcaggcgat aaaaatgcag tatgatgtct ggaataataa aaataaagca
    11161 gatcatgaga tgttggtcac acaagaacaa gaggccttta ttaaacagca gaaagaagct
    11221 gaaccattaa cttttgatta aaaggtggat atatggctca ggggtttttc gttaaatata
    11281 attctaccgt tatggattcg gtagataaaa tcagctccag ttatcaaaca caatttgcta
    11341 atgatattat gtcgttagca acggtatcgg ttacgttata tgtactatgg aaaggatatc
    11401 aaatacttgc cagtaaaact cagacgccct tgcaggattt agtatgggat ctatcaaaat
    11461 ttgcaatcat aatcatgttt ataactaatg cggatgggta tttaactgcg gctactgatg
    11521 cgttgcaagg catgaaagat ggtttttctg gaggggtgag tgtctggcaa actttagata
    11581 acttatggaa aagtacgcaa aatcttggtg cggaaatata ctctttagat aaatcaacat
    11641 atgttaaaga tcaaggtgta gttggtcagt ttttaatatg gactggctcg cttattttaa
    11701 tggctgttag tgtggttgtt tttttaacag cagatgtaac gatgaaactc ctgattatta
    11761 cagcaccgat atttatcttt tgtctcatgt ttggttttat tcggagcatg tttaataatt
    11821 ggttacaatc gttattctcc agtattctga cagttctatt tgccagttta gtgattcgga
    11881 tagcaatgga ttttcaaggg atgatccttt cccatgctat tcgtgctgca caaacaggga
    11941 atgtaaatct tgtatctaca ggtgctatgg gctttatggc tgggtttttg ggggctttat
    12001 tggttcttat agctaaaggt tttgctgtcc agttagcagg tgcaggtgtt gaaggtgctg
    12061 ttcagggcgc agccatgatg gggctgggtg ctgctggtat ggctactggt aagtctctga
    12121 tgcttggcgg tcgtgctggt ttaggttttg gcttagggat ggccggaaga acgggcatga
    12181 attctttatc agggaaagca gggaatctga tggggcgtgg tgcgcgaaca gccgctgaat
    12241 gggcgggtga aaagggatat caggcgctgg ctccgacagg tgctttgggg atgaaggcga
    12301 gaagacttgc atccctggaa aaagcacgag cgaggaacgc cgcatgaaaa taatgaaacg
    12361 ttttttttat gtgatgtccc tgaactggat actggtgttc gttgataaac atatcacctc
    12421 cggatggagc aggaagagaa agctaataac ccagcttgtt attttaatca cgggaattac
    12481 cttatttaag gtcttaggtg gaatcagtca gagctggttg tgacatgctt cattattttg
    12541 tcatgatact ttattttgtc ctaatccttc ttttaggagt gtttacctgc ttcgcaggaa
    12601 taagacttgg tttagggctt gcggggaaat ggagaaaggg tatggatctt cgctttttgc
    12661 ttcttattgg tgggattctt tttcttcatc ttggccttta tctcttaaag gtgttcgtga
    12721 acgcttaata aggtgaattt atgcgatgtg tgattctttt gtttttcctg tttcagattt
    12781 ccggatgtac cacaaggaat aaccttcctt ctgatgtttc cggcgaactg gaacccatta
    12841 accacagcca ggtaatcagt tatgagtgaa aaaatcgaaa agaagattga gacagctaaa
    12901 tccttcgaaa gacaactcta tgcagaaaat gaacggtcta agaaaaatgc atggcgtgtt
    12961 gcagtggcag catcattact gtccttatgt cttggggctg caatttgtgt tcttgtgcca
    13021 ttaaaagaaa aagagcttgc tattgtggct gttggcgaaa aaacaggccg tacagaactg
    13081 attactcagg ttaaacagga aaagatcctg caatctgaag cacttgggcg gtattttgta
    13141 aacacgtata ttactttacg tgaaggttat aattatccgt ctcttcagta tgattatgag
    13201 actgtacagc tatatagctc gaatacagta aaggacgatt atcttcgtct gtataacagc
    13261 gatatggctc ctgataaaat ttatcataat aacggttctt acgttgcggt tgaggtcatc
    13321 tccaatatta tttctgacgc aaccgcgcca gataaactgg cctctgtgcg ctttaaaaaa
    13381 acgacgagaa acttcacgac cggacaggtt tcagtttcat actggacggc tcgtgtgaca
    13441 tatcgttttg aaccagaaaa gtcggttaaa agttccagtc gtgagcttaa tcctctcggt
    13501 tttactgtaa ccagttacca gacagatcgg gaagtcaggg gggaatgatg aagaaattat
    13561 ttattgctac atgtttattg cttcctgggc ttgtgtattc agcagcgact ccgttacctt
    13621 ctggatttga tgcaaggatg cagactgtga gttataacgg tgcgaatacg accgttatcc
    13681 ggtcaaagac aggatttctc acatcagttg tttttgatga aggtgaggct gttatcagtg
    13741 caaaggctgg ttttcctgcc ggatgggaaa tcacaaccga tgataatgtt gtttacatca
    13801 atccgcgtcc cgttgttcag gaacaggaag gcgatgaagg cgaaaaactg aaaaaggttt
    13861 tccagccaac agaaaaggaa tgggatacga atctttttgt cagaacaaca aagcggattt
    13921 acagtctgga tctaatcctt ctgtcagaag aaaaacaagc gcaacctgct tatgttgtac
    13981 aattccgcta tccatcagaa atagcgaaaa agaatgcaga agaagtaagg ctggcaaaag
    14041 aaaaacagga aaaactcaga cagaagaaac tgatttctga aagttttgaa aaagccgatg
    14101 cgcctaaaaa ctggaattat ttcatgcgag tcaatgaaaa atatgacagt cgtcgtatcg
    14161 cccctgattt tgcttatgat aatggcatat ttaccttttt aggttttaac tcagggaaag
    14221 tattcccagc tccatttgct gtaagagatg gtcaggaaca gacacttgct tttaatgtgg
    14281 aaacaaaagg caagtataaa attatggtta tccacaacgt taatgacaaa tttgttttac
    14341 gctatggaaa cagcgttgtt ggtgttgtga ataaatcttt cggaaaagta ttaaccgacc
    14401 agaggaatac atcttctcct gcggtagaac gtgttgaggt gaataatgac tgatatgaaa
    14461 aaaacagatg atttagttga tgatgcgaat cagtcaaagc tggaaagtaa acccgttcat
    14521 gatatcggtg atatcaggaa caaaaataat cgtatgcgtt ctggctttct gtttggtctg
    14581 atggctgtat tagttattgg tatttttgcg ctgaaaacat ataaaaatta ttttgcagat
    14641 gaccagcaga aagcatcaga atcaacaggc gataccagca tttctcaggt aagtaaaatc
    14701 cgtactggtc ttggtcagaa ttttgaccct gttgagaaca aagcaattat caatccaggc
    14761 gctactggtt ctggtaatac tgtttctgac ggtcataaag aagtgccaca ggaggggttc
    14821 aggaaatatt tgtcaatacc tgttgctggt cagggaggga gtcagactgg cgcgagtggc
    14881 agcagcagga catcgcagac atcagagcca caggaagaaa ggaaagaatc aaaagaaaat
    14941 gtgcctggta aatcaggaat gaaagtaact gcgattaatc tcgatcctga tctctatatt
    15001 gaggaaaaca ggcttatacc gtgtgcttta accacacgct ttgtttctga tgttgcaggt
    15061 cgtatcagtt gtgtttttac agaagatgta tggagtgcta atcaccacac aaaattactg
    15121 gaacagggaa ctaaggcttt tggtcgttac cagaccggaa cgctgaatca tggacagggc
    15181 agaatgttcg ttatgtggga gcagttgcgg acgcctgata ataaacgaat cgatatggta
    15241 aatacagcag cagctggtcc cctgggagaa gcgggcattg atggatggat cgattctcac
    15301 ttctgggagc gttttggtgg ttctcttatg ctcagtatgg ttcaggatgt agcggcggcg
    15361 gcggcggata atgcacctgg taaagatcgt aatgtggatt ataccgaaaa ctcacgacag
    15421 gcaatggctg aaatggctaa agtcgcactt gagaattcga taaatattcc tccaacaatg
    15481 tataaaaacc agggtgacat aatcactatt atggtcgggg aagacattga tttttctgat
    15541 atctatgagt taaaggtaaa atagtatgag tggcgttatt cctgtcagca ttagcaataa
    15601 atcgctcgat ttttataaaa atcaagtatt ccagtctttt cttgatattg aagggctaac
    15661 agaaattgct gtcaaccgtc ctggtgaaat ctggacggaa attaatggtg actggacatt
    15721 ccataataat gacagtgtga cctttgattt ttgtaaacgt ttttctcata cgctggcatc
    15781 atttcgggga gatgaaatcg gcgagaccaa gccattactt tcagcaacac tggaatcagg
    15841 agaacgtgta caggtcgttt ttcctcctgc atgtgagaga aatactattt caatcactat
    15901 acgtaaacca tcgacacggc agataacaca taaagaatat gtggcgaacg gtttttatga
    15961 ttatgtccag tcaggaaaaa aacacaggac atacgatgat gagcttcttg atttattcag
    16021 agcgagaaat atcgctgctt ttatggagct tgccgtagca gcagggaaaa ccattgtatt
    16081 tgccggagca acgggttccg gtaaaacaac ttatatgaag agtcttatcg atttcatacc
    16141 attgaataca cggctgatta cgattgaaga tgcagaggaa atcaaatttt ttatccataa
    16201 aaattatgtg catctttttt acccttcgga atccggcagt gattccggct ctatcataac
    16261 agcagcgaaa ttaatcaaat cctgtttgag gatgaaacct gacagaattt tactggcgga
    16321 aattaaaggt ggcgatgcct gggattttgt gaaagttgct ggttctggtc acagtggaag
    16381 catgacgtcc attcacgcgg cctcggcaaa agatgccatc attcagatgg tgacaaaatg
    16441 ttatcagaac agagaatgtc agaatcttcc ttttgatgtt cttcgtaaaa tcattatgga
    16501 cagtattgat attgttgttc atgtaggcag ggatggtgtt gtcaggcata tgagcgacat
    16561 ctattacaaa ggggctgaat gtgaaaactt ttaataagtc gcaatctgtt tttatattcg
    16621 ctgttatgct tgttgcggca tggtttgcag gttcatttat tttctttgtg ctttacttca
    16681 gccagataaa gaatctgaaa ccattgaagg ctgtgttcag atccattgat gcgtacagga
    16741 tggatatttt tacagacagc cttactttat ctgttgtgac tacggatatc agagttttag
    16801 cctttgttgc acttggagca ggatttgtcg tgtctcttat catccctgtt gcggcgttga
    16861 taaaactgaa cgagaagaaa gaaaatattt tcggtgatgc gcgatttgca acaattaatg
    16921 atattcgtga gtctaacagt ttcacgcttg acggtgacga aaaagacggg attatcgttg
    16981 gtataaaaga caagaaaatc atacgctatg tgggagcagc attcagtgct atgggagccg
    17041 gaacaagggc tggtaaaggt gctggtatag tcatcactaa tcttatgaag tactggtgga
    17101 gtgttattat tctcgatcca aaaagggagt gttttaatat caccagtctt atcaggaagg
    17161 tgattttagg tcatgaggtt tataaatttg atccctttag ttcggtaacg caccgcttta
    17221 accctttgta ttatgtcagc atgggaacga gtgaaggttt taatcagctt gaaaatcttt
    17281 cgttgattat ttacccctat aagacagatg gtgcggatgc tggtagctat cttaataaga
    17341 cggcgggtgg tgtttttaaa tcttatgctg tcgctttatg gtttatgatt aagaatgata
    17401 aggctggact aaaaacgctt gatattgagc ctgtcttctc aatgtctaaa attaatcagc
    17461 tttttgagcg tgcagaaccc gaacatcttc tttcattcat gaatgatatt cgttcagaat
    17521 taagggggaa agacaaaacg cttgctgata ttggtgtcgc tggccttaag gcattcattg
    17581 agatggagga taaaacaaaa gcacaactca aaagcaactt tcttaatgga ttatcaccgt
    17641 ttgctaaccc caatgtggca aatgctactg atggaaatga ttttgatttg cggcaggtgc
    17701 ggaaaaagcg gatgacaatt tatttctgta tttctggtga taatgccagg ttggctgaaa
    17761 aaataacaaa tattttcttt cagcttgcta tacaggtgaa tcttgaaaag atgccaacgg
    17821 atgatccgga aataaagcat gactgccttt ttctactgga tgaattcccg tcaattggtg
    17881 ctgtagatta catcaagagt aaatctggtc tcattgctgg ttacaagctg aaattgttga
    17941 ttgtttacca ggtcggctct cagcttgagg aaatctacag ttatgcaggc agtaaaacat
    18001 tactggcaag tgcaccctgc aaaattgttt attccgcttc tgatgttaaa gatgcgcggg
    18061 agttatcaga agcgatgggg acacgaacag taactatcgg ttcgaaaagc aaaagtcgta
    18121 gtcgtggagg aacatcgaga tctgaatcag aaagccttat tgagcgtcca ctggtaacaa
    18181 caaatgaact acttacactg aaatttagtg aagaaatcct ggcaatgaag ggagaaaacc
    18241 cgattcgttg tgaaaaggca ttctactatc tcaatgagta tttctttggt gactttgtga
    18301 aggttgctcc ggaacttgca aacattttcc ccaggaagaa aggaaagctg gttatgcctc
    18361 cacagaaagt atttgaaaat gaaatcgtcg caaaagggta tctggtagta aaagatgttc
    18421 ctgatctcga taaagcggca taaaggagaa catgatgaag aagttagtgt ttttattgat
    18481 ttccattctt gctggttgtt catcaccgcc agagccaaca cccgtgcagt ttgaaaaggc
    18541 aaatgaagtg atcaatccct cattgccata tgtccccgat tttcacggtg tcataaagtc
    18601 agacgttagc ggtaaaggat gggtttatga gatcacttcc ttatccggag tacaggccag
    18661 aacgccgacg ttttattacg ctctggctca tgcggacagg attgtagtga caacacatga
    18721 tgctgggctg tggtttcgaa tcagagatct gttgaagatg gaaggggcaa cagcagtcgt
    18781 ggaatggcga aacgagaaaa gttttttacc tgaacaggta aaaatagttt tcattaaagc
    18841 acaaaatgag gtgaaaaatg actggaaaaa atagagtggt tttaccagcc ttgctggcgt
    18901 taggattaat atcaacaaat gctaatgcat ctgacccttg cgcttcggta ctttgcttat
    18961 atggaaaagc agtcgggcaa ggtggaggga gtgaatgcag aagtgctgaa aaggattttt
    19021 ttaatattct gaaaaagaaa aaaggaagca ttcgctggag taaaactttt gatgcccgta
    19081 aagcatttct gaatcagtgt tcaacggctg atcctgctgc tatatcaaaa atcatgagta
    19141 agtttggtcg tgtcagaggt taattaaaac ctgataaccg cgccaacggg tatcagggta
    19201 ctgcaagtat cacatttcgc gccaacgaaa tgtgatgatt agttacaatc actgaggtta
    19261 gaaatgaaag taaccaaatc tattatagct attttattgt gcttatctgc tggtagtgca
    19321 taagtggatg taataaaaaa tgctcgtgcc tttttgaaag gaaccctcga tctgagcgtt
    19381 caggaagcag atgaagatat agaggaaagg gaagaacttt ataaaaagaa cggggcacaa
    19441 cctgactatt taagttacct ggaggattaa cacatgcaat atgcattgtt tgatggattt
    19501 gaacgaaagt ttttgctgga tgctcttgaa ttcggtgttc tgaaggactg gaaagaaaat
    19561 ccggtaaaag aacttcctga tattgatgaa tctgctcacc ccttccatat ctgttatggt
    19621 ggatatttat taaaccctgg tgtttcagat tcagatatta gcagaaaaat aaaagaccag
    19681 gcaggattct ggctggcagc tattgatgat acccgcatgg attgtcattc aatagcttat
    19741 tatgatattc acacactccc tctgatttcg tgtggtcatc aaaagatagt tccttttgcc
    19801 gcgttaataa aagctgatga atgcatcatt tcaaaaattg cttcgtattc tggttttgct
    19861 gtaacagcct ttttgagaat taaagagtgg gatattgcaa ctaatatact taaccgtgag
    19921 ggaatttttg cctttaatgg ctgtgagcgc agattcagag tagtaagtaa agataactgg
    19981 caacatacag tatcggaaga acgcgctatc cgttgtgcca aaagattaat tcaatgtaaa
    20041 ggataacaaa atgagacttt ttatcgcaga aaaacccgca gtagcaaatg atattgttaa
    20101 ggcacttggt ggcaatttta cccgccatga tggctggttt gaaagtgata acgccattgt
    20161 gactaactgt tttggtcata ttatcgaatc acaaccgccg gaaaactata atcctgaata
    20221 caaagcctgg aaggttgaaa cgcttccttt acgtctttat cccgtgaagt atcagcctgt
    20281 tgaaagtgca gcaaaacagg ttaaaacgat tctcgaactt atcagacgtg gagacgtgac
    20341 tgaaattgtt cacgctggcg atcctgatga tgagggacag ctactggttg atgaagtcct
    20401 ggaatatgca ggcaacacaa aacccgtaaa gcgcgttctg attaacgaca acacgcttcc
    20461 ggcagtgaaa aaggcactgg caaatcttaa agacaatcgt gatttcaaag gactttacct
    20521 taaggcgttg gcgcggtcag ttgccgatgc cgtctatggc ttctctatga cacgtgcgta
    20581 caccattccg gcaaaagcca gaggatatca gggcgttctg tctgtcgggc gcgtccagac
    20641 tcccgttctt ggcctgattg tgaatcgtac ccgtgctaac cagaaccata aatccagttt
    20701 ttactacacc atgaccggag tctttcagcg tggtgctgat gttatcaggg cgaactggaa
    20761 gccaggggaa tttgctccgc tgacagaccg taaattactt gataaagcgt gggcagacgg
    20821 aacggctgca tcccttgcag gaaaaccggc tacagttgaa gcagcagcaa ctgatgataa
    20881 aaaaacggct gcgccgttgc cgtttaatct ggtcagactc cagcaataca tgaacaagaa
    20941 gtttaaaatg acggcacaaa aaacgctgga tattacgcaa caactacgcg aaaaatataa
    21001 agcaattacg tataaccgct ctgactgctc atatctttca gatgaacaat tcagcgaagc
    21061 gccgcaggtt atcgatgccc tgaaatcagt ctttcctcag tcgctggata ttgattctgc
    21121 acgtaaaagc aaagcgttta acagtgcaaa ggtgactgcg catactgcga taatcccgac
    21181 cgccagtgtg cctgatgtta acgcactcag caccgacgag cgcaatgttt acctggcgat
    21241 cgcacaacac tatcttgttc agttcatgcc tgaaaaagca taccaggaag tatcggttgc
    21301 cattcagtgt ggtgatgagt cgttctatgc ccgtgccaga aaaacaactg acagcggatt
    21361 tgaggcgttt cttggcgcgg aaaccacaga cgaaggtgaa tcagaagata atgatgattc
    21421 cgcttttgaa ctgctctgta aaattcgcac aggagaaaca ctgacgacaa aagaagttat
    21481 tgttaatgag aagaaaacaa caccgccgcc gttattcacc gaagcctcct tgcttgctgc
    21541 gcttgttcgt gtcgcggatt ttgtcactga tccaacaatt aaaaaattgt tgaaggataa
    21601 ggataaagac aaaaaagatg aacatggtgg cattggtacg ccagctaccc gcgcagccat
    21661 tctggaaacg ctgaagaaaa gaaactatat cacgctggaa aaagggaaac ttattcctac
    21721 tgataccgga tatgcgctta ttgatgccct gcctggtata gcggttaatc ctgatatgac
    21781 agcattatgg tctgaaaagc aggctgccat agaaaatggc gacctgacgg ttgaacagtt
    21841 tattaatgat ctgtacggtg aactgacagg catgatttct gatgttgacc tgggcgagat
    21901 gaagattgaa cccgctgcgc cagcagggca gtttcaacgc ctggactctc cctgcccttc
    21961 ctgtggtaaa catattgtta tcaggccgaa aggttatttc tgtaccggat gtgaatttaa
    22021 aatctggagt gagttttctg gtaagaaaat cacccaggca caggccgaaa aactggttaa
    22081 atcagggaaa accgatttga ttaagggatt taaaaagaaa agtggtggaa cgtatgatac
    22141 agttcttgtc cttgaggata agaaaacagg gaagctgggt tttccggcaa gggctaagaa
    22201 gtgaaaacaa agcaggaatg gctttttcag ttaagaaaat gtacatcaag agatactctt
    22261 gaaaaagtta ttgagattaa ccgttacaaa ctgcctttat cagaatcaga ggcattttat
    22321 tctgccgcag atcatcgccg agcagaactg gtgatgaata aactttatga taaggtgcct
    22381 tccggcgtct ggaagtacgt acactaaata agaggattaa ttatatgagc gaactgacta
    22441 aagaagatga atacggcatt atcagccgta ctatgatgaa tattcgttca ttgcgtgttt
    22501 ttgcccgtga gattgatttt gagcagttgc tcgaaatgca ggaaaagctc aacgttgtta
    22561 ttgaagaacg tcgtgaagat gctgaacgtg aagcggctga acgccaggaa cttgaagcca
    22621 aacgtcagca ggccattgaa tacatcatat ctttaggtct tgatcccgaa tcactccttg
    22681 ctcctgtaac agcagataca gtaaaaacca ggcggaaagc caaaggcgga gtaagaaagg
    22741 ctaaataccg ctttaaggat gaaaatggcg agatcagaga atggtctggt aatggcaagc
    22801 gtccgcttgc tttacagaag ctgcttgatg aggggcattt catggaagat ttcctcattg
    22861 agaaaactaa gccggaacag gcagaataac ccgccaagta tacatcacac agggcactgt
    22921 tgcaaatagt cggtggtgat aaacttatca tccccttttg ctgatggagc tgcacatgaa
    22981 cccattcaaa ggccggcatt ttcagcgtga catcattctg tgggccgtac gctggtactg
    23041 caaatacggc atcagttacc gtgagctgca ggagatgctg gctgaacgcg gagtgaatgt
    23101 tgatcactcc acgatttacc gctgggttca gcgttatgcg cctgaaatgg aaaaacggct
    23161 gcgctggtac tggcgtaacc cttccgatct ttgcccgtgg cacatggatg aaacctacgt
    23221 gaaggtcaat ggccgctggg cgtatctgta ccgggccgtc gacagccggg gccgcactgt
    23281 cgatttttat ctctcctccc gtcgtaacag caaagctgca taccggtttc tgggtaaaat
    23341 cctcaacaac gtgaagaagt ggcagatccc gcgattcatc aacacggata aagcgcccgc
    23401 ctatggtcgc gcgcttgctc tgctcaaacg cgaaggccgg tgcccgtctg acgttgaaca
    23461 ccgacagatt aagtaccgga acaacgtgat tgaatgcgat catggcaaac tgaaacggat
    23521 aatcggcgcc acgctgggat ttaaatccat gaagacggct tacgccacca tcaaaggtat
    23581 tgaggtgatg cgtgcactac gcaaaggcca ggcctcagca ttttattatg gtgatcccct
    23641 gggcgaaatg cgcctggtaa gcagagtttt tgaaatgtaa ggcctttgaa taagacaaaa
    23701 ggctgcctca tcgctaactt tgcaacagtg cctcacacag acatacacat aggtatgtct
    23761 gtgtgacata cctatgtaca gtgccagatg gcgttgctac gtgaaaaata acctacccta
    23821 cccctgcttt tttcgcagat tttacgtagc acaccgttgc tatagcattc atctaaaaag
    23881 ctgaatgtcc ttttctgtcg ctgttgcatt ttaattcact gaaaaatatt gagtaatgaa
    23941 aatgccggta acgcgtcaag ctgttggcca acgcgacagg cagtattgga agcaacaaaa
    24001 aaaatgaaag aaaaatccct caaatgaagg agaaaaaacg gaactacagc cgaacgacag
    24061 gcacaaaaaa acccgactgg taatcgggct tttttgcgtt ttccagtctt gagttggtgg
    24121 ctctgaccgg agaaggttac tctacaccta acgtttacat tttattcact atggtgctgt
    24181 aaagcaacta aatgtggtta aggaaccaca tttagtggtg taacgggtgt tttgtgtagc
    24241 gtataatcag tcagttagtc atgtagttgg cttgcaatcc tgctgttccc gtatctgcgg
    24301 gtatgaacga ttttaaagtc ctggctggat aaacaggtgg tgctgtattc ggtgctctgg
    24361 caggaggagg tcactctaca cctaacaatg cgagagagcc gttgtgacag gcagtgtatg
    24421 agcaagcaac ggtgatttcc tccagtttta ctggagaaac ggatgattaa tatgttaatc
    24481 atcgttctca gagctgtggt cgccgttgca aacgcgctga ttgcagttct ggaactgatc
    24541 cgccaattca tcgattgatg acaacggaaa cgtaactaag ggcaggaagt gaaccgcttc
    24601 ctgcccttta acaaaaaagg aggatttatg gattttatga gcattttggg gcgctgttta
    24661 cttcttcctt tccctgttgc gatgtttgtc ggttgcctgt ttcctggcat cgatgatcgc
    24721 ttatccggaa tgcttatgag tgttgctgtg ggatgtttat cgtggtatgt caccagaccg
    24781 aagaaccgac agacaaaggc cgcgtaagtg gcctttaatt gggataccct ttagttacaa
    24841 cattctaata gctcattcca tcctccgctc atccagcaaa cataacctcc ctgcccctcc
    24901 ccactacaga aagtggcgcg ccccgcccgt acgggcggaa tctaatcgct taattttgaa
    24961 tgttgtaact aaacatactc attgctgtat tgccacaagg tttcgcagca agggaggata
    25021 ccgaaagtaa cgctgtcact tttgctttca agtgaccaac caacgggtac atcacactga
    25081 catacaataa tgtatttctt catgatgtac atcattgtaa ttcattgtga catacactat
    25141 agtatgtcca tgtgacatac gcatgcgtac atcacataga aatacacatg agtaaatcac
    25201 tgtgacatac aaggggtact atgattatcg taatcggtgg tgataaaggc ggtacaggta
    25261 aatcacatct ggcaaccaac ttaactgttt gcctctcaca acagggaaag agaacggggc
    25321 ttgttgaaac agacctgaat ggctcgacca aaaaatggaa taaacgcaga gaacaggccg
    25381 gattaccgcc cgtcgcatta aatgaagcct atggcgacat cagtgccaaa ataacaaaaa
    25441 tggcagatgt agcagaaatc ctcattatag atactgccgg atatgacagc acggagttca
    25501 gaactgcact aaaagttgca gacattgtga ttgtcccgat cgacccgctt gcccaggtgg
    25561 aagcagacag tcttcagact gtgacaaaaa ttgtcaggga tgcgcaaaaa ataaatccca
    25621 ggctggctgc acatgtgctc ctgtataaat gccagccaaa tacgttcagt gaacaacaag
    25681 aattaagaga ctctctcaac agccatgatt actggcttaa accaatgaaa agcacggttt
    25741 cttttctccg ggcctttgta agagcaatga atcagggaat gggggttcac gagttaaaaa
    25801 gtaatgttag cggtgccagc caggcaaaag cacaaatcga actcttgctg aaagaactgg
    25861 aactgtaaat catagtgaca tacactaatg tacatcatca tgatatacat tagtgtgaaa
    25921 caatcagatt agaaggtaca tcatggcaaa gctggaacta ccagaactag aacaaaacca
    25981 ggaagtgaac gccacaaaat ttgttcagga cgcaggaaaa cgccccacag agaacaaaac
    26041 aaaactggct tcattccgca taccgaatga attgcttgaa ttcattgata acgaatcaaa
    26101 aagactgcat cgtcccaaga caaaaataat caaagcagca ttactggctt atcaggatct
    26161 ggacgaaaac gaactcatta atttgtggtt cagagctgac agaaatgatt aatcatagca
    26221 agtggcccaa taaactcttt atcattttct tttagatact tatctgaatg tactaacttc
    26281 atcactttta aatgtagttg tgattcattt ttagttactc ttgcaataaa atacccttgt
    26341 acagttgttg cacgggtatt taggagcact agatgagcct tatcgattta agtttatcag
    26401 gattatcaga accaggaaca aaacttattg aaaaaataag tgatgctatt ggtgtgcttt
    26461 atgaacctac aagaatcagg aaaaaagcga aggctgaagc tgaagctaaa cgcacagagc
    26521 taatttctag gttagagctt gagggaatag aaaaacgggc agttgagcgt tttctcaaac
    26581 gtgaaacgaa acgacaggaa aacattgaaa atataacaat gcaagcagca caaagtctat
    26641 ctgagagtga taatgtttct gatattgacg aagattggat agaggctttc ttcagggagt
    26701 gtgaggatat tagtgacgaa caaatgcaaa tgctttgggg aagaatttta tccgaagaag
    26761 caaagtcaaa aggttcgttt agtcgtagaa ccttaaaact attatccact ataagcaaag
    26821 aagaagcgaa ccttattact tattttggaa agtttgtttg gcaggcaaac aaactcactc
    26881 caattttatt taccgatgag aatggagata ctgaaggtat aactttcgat aaactttcgg
    26941 ttttagactc cttaggcgtt attcaacaag gcattggtta tagtttaaga tacaaattat
    27001 aaatactctc aagtgtatat tcagtatggg attgcgcaat gattgcctaa taaaatttct
    27061 gaaatatttc tgtatcgcat aattttttat atcagataaa ttgtactgga tttcttaaaa
    27121 aattgcagta tgattgccgc aattatccca ccgtttattt tttgagtagt ttctcatgat
    27181 gcagcatact tctgtgtggt accgacgctc ggtcagtccg tttgttcttg tggcgagtgt
    27241 tgccgttttc ttgaccgcga ccgccaatct tacctttttt gataaaatca gccaaaccta
    27301 tcccatcgcg gacaatctcg gctttgtgct gacgatcgct gtcgtgctct ttggcgcgat
    27361 gctactgatc accacgctgt tatcatcgta tcgctatgtg ctaaagcctg tgttgatttt
    27421 gctattaatc atgggcgcgg tgaccagtta ttttactgac acttatggca cggtctatga
    27481 tacgaccatg ctccaaaatg ccctacagac cgaccaagcc gagaccaagg atctattaaa
    27541 cgcagcgttt atcatgcgta tcattggttt gggtgtgcta ccaagtttgc ttgtggcttt
    27601 tgttaaggtg gattatccga cttggggcaa gggtttgatg cgccgattgg gcttgatcgt
    27661 ggcaagtctt gcgctgattt tactgcctgt ggtggcgttc agcagtcatt atgccagttt
    27721 ctttcgcgtg cataagccgc tgcgtagcta tgtcaatccg atcatgccaa tctactcggt
    27781 gggtaagctt gccagtattg agtataaaaa agccagtgcg ccaaaagata ccatttatca
    27841 cgccaaagac gcggtacaag caaccaagcc tgatatgcgt aagccacgcc tagtggtgtt
    27901 cgtcgtcggt gagacggcac gcgccgatca tgtcagcttc aatggctatg agcgcgatac
    27961 tttcccacag cttgccaaga tcgatggcgt gaccaatttt agcaatgtca catcgtgcgg
    28021 cacatcgacg gcgtattctg tgccgtgtat gttcagctat ctgggcgcgg atgagtatga
    28081 tgtcgatacc gccaaatacc aagaaaatgt gctggatacg ctggatcgct tgggcgtaag
    28141 tatcttgtgg cgtgataata attcggactc aaaaggcgtg atggataagc tgccaaaagc
    28201 gcaatttgcc gattataaat ccgcgaccaa caacgccatc tgcaacacca atccttataa
    28261 cgaatgccgc gatgtcggta tgctcgttgg cttagatgac tttgtcgctg ccaataacgg
    28321 caaagatatg ctgatcatgc tgcaccaaat gggcaatcac gggcctgcgt attttaagcg
    28381 atatgatgaa aagtttgcca aattcacgcc agtgtgtgaa ggtaatgagc ttgccaagtg
    28441 cgaacatcag tccttgatca atgcttatga caatgccttg cttgccaccg atgatttcat
    28501 cgctcaaagt atccagtggc tgcagacgca cagcaatgcc tatgatgtct caatgctgta
    28561 tgtcagcgat catggcgaaa gtctgggtga gaacggtgtc tatctacatg gtatgccaaa
    28621 tgcctttgca ccaaaagaac agcgcagtgt gcctgcattt ttctggacgg ataagcaaac
    28681 tggcatcacg ccaatggcaa ccgataccgt cctgacccat gacgcgatca cgccgacatt
    28741 attaaagctg tttgatgtca ccgcggacaa agtcaaagac cgcaccgcat tcatccgctg
    28801 atttctccct gtattttttc caaacccacc gcacactcca ttcgtattat gggcggtggg
    28861 gtggggtttg ttatgccgta tttatcaaat aaacgcctac ttgctgagat gagtatcgct
    28921 cttgtcatgg cgatcgttgc cacgctgacc cttgagcaca gtcagattga tctgatggtc
    28981 gctgattggt tttatctggg tatggggcat tggatggttg ccaagcaagc ttttttgcca
    29041 gatttgctac tgtattctgg actaaaaaag ctgctgatgg cgatgctgat ctacttgctg
    29101 gttgcgacca tttgccgtgc ttatcatgag aaaaagggca atgctatcac tgccaagtgg
    29161 cttgtcccag tgacaaaatt tcgcgtgcgt gagcttgcgt atctggtgct gactttgatc
    29221 ctagtgccga cagttgtcgc gtcattgaag gcatatactc atgtggtctg ccctgtgcat
    29281 ttgacgattt ttgatggtac gctgccgtat ttgccgatgc ttgatagtat gcgtaacacc
    29341 attcctgata agtgctttcc tgcggcgcat gccagtagcg gatttgcgct gtttgccttt
    29401 gcgtttgcgc caagtttgcg ccgccgtcgt ggtgcgatca tcatcgtggt gatggcattg
    29461 ggctgggcga tgggctgcta taagatgatt attggcgatc attttttgag ccatacggtg
    29521 gtgtcgatga tgcttgcgtg ggcgatgtcg gcagggcttg cgtgggtgtt ttttaagaag
    29581 ggtgaacaag tttaatcggc tttaaaagta aaaacggtcg tatcggttat tacggaacgg
    29641 ttttttcagt tgagtttcaa agcgataatt catcaacctg gaaactacca ataggaacgg
    29701 ctttacttac gcctatcggt caagaattga tgaaaatatg cggttccact ccagatattg
    29761 cgtatttaaa taaattcctc aacaaaataa atgttgaagg aagccaggta aaactatcaa
    29821 ttattaatat gtaaagaggt cgagttacct gtctgagttc cactaaccat aattaaaagc
    29881 gaccgcaaaa actgcccagt gaaaactgtg ttgccagtaa tcacaaatgc agcaagtact
    29941 aataaagagc ctgttaagcc cgcaaatatg tgggcttatt tttaattact cttcatcatc
    30001 ccgcaggaac tgacaaaaat cttcgctccc catcatatcg acagtgtttt taaattcgaa
    30061 aaaagaaatt cctgtcatag cacacacgcg ctggataatc agttttttct tttgctgtct
    30121 gacggttgcg gtttcaccaa actggataac agccaggact gtttcatcat atgatttcag
    30181 gacaaaatca caggttatat tctgcacttc acggattaaa tcttttacag cttcctcgct
    30241 accatgagga cgaacaaatt caatgagccg tattttggga aaaacggaat aatcaggtat
    30301 aatattacgt gaaagaatgc ctaaaaactc tgattcatta tttgagagta agggtacttt
    30361 agtaaaacaa tcaacctccc caatggctgt aaaagcattg gttgtcaaag ctggattgtt
    30421 cttaataaaa tcagagaata cattttcagc tgatggcaaa acaacagcag aattatgttg
    30481 ttcatctcgt tttttattac ggttaaatat catttcatat tccttttaaa agagcctgcg
    30541 gcaggcacag gcaaaaacat cgtttttgga caatctgatt caaatgttaa catttgacat
    30601 cggattgtct atcctgcatt gttctttact gtctgtaaga tcggcgctca ttcttccggc
    30661 gttctcccga taccaaaaag acggaacgca aaacggcttt cgatccacca ttcaaaaatc
    30721 tgctctgcgc aaccacaaac agttaaggcg atccatgcag caagaacaac gtaactactg
    30781 acatctgcac ccatgtacca ggcgatagtt aaacccatca ctgcgatacc gcctaaaaac
    30841 tgcaacaaga aacgaaatcc cgcaagaatc cccaatggaa taacaacaac cagataaagg
    30901 gaagcagcca gaaggtatct gacaggtgtc agcagataaa agaacctgga tattttcttt
    30961 ttgtcagaat aaacggcatc atttgcaaca tcggttgaat gatcattcat gctgtccctg
    31021 attctttgaa aatctacgat attatccttc atattgttat gacctcaatt ttcaggtggg
    31081 tacattttat caaacatatt agtaaactct gagtcttccc tggtatcgcc ctcataacca
    31141 attgtataag agaactttaa tttataaact tttctcccaa ttttttctga aactacgaaa
    31201 cttaagttct ttacttccgt atgtttcatg atttctttta ctgatttatt aagaacatct
    31261 cttttaaaag caggataatc tggatactta taatcttcac cccccgccct attgtataaa
    31321 gattcaattc atctttaagt tcatctattg tcatttcaaa actattcgcg cgagaattat
    31381 tactatatat tttacgaatg agttgatata gtgatgcagc attaacactt gtcagtcgaa
    31441 caacagataa taaaacttgc gttgtataac gtttttcttc accaataagt ttacataaaa
    31501 atcttttcgc ttctttcgta aacttgatcc ccactctacc ttcattcctg taataagtag
    31561 aaaaaacagt cagactcaaa ttcattgaat caggtacatt acttttagtg aacttaaatc
    31621 ccaaatcact actcagttct aatatttcat catgtttcag cttaagaagc gtcgtatcta
    31681 atatattaga gccatccctc aaagcaagat aagccgcatc aggcttaacc tgaacccatt
    31741 taatgtaatc ggcaactgtc acataaaata tgtgatcatc atcgaattca tttttagagt
    31801 ttatctggca catggctaaa aataagactt ttttagcagc cataggcaat gttgacagcg
    31861 ttgaattcaa ttcatttcga tgtctcactt ttgttaagcg agaaagggaa gtcttatttg
    31921 tcgtcattct cattgttcca acactcttga taatcagact ttaacaccag aaacatgata
    31981 ttacaacaca atcaatatca tgtttaaccg agtatcttct catgttcata tctgtgattt
    32041 atctcacaaa ggtaatccat gctcaaaatc acactggatt caaggcagat taacaacaga
    32101 ttcaaaatag attcaccaga aagaacaacg aattagtatt cttatgacac attttgtgga
    32161 tatcaccgag gaagctctca tgtttaaccg aggaagctct catgtttaac cgaggaagct
    32221 ctcatgttta accgaggaag ctctcatgtt taaccgagga agttatcatg tttaaccgag
    32281 gaagctctca tgtttagaca aaaaacacgc ttaaaatcaa taaattagag ctactctaag
    32341 tttttaagtt tttaagaaaa acaagaaaag ataaggcttt taatgcgtgc gaatattcag
    32401 gaactgtgga taactcaaca aaaccagcaa cgatgatggt tccttaccat aaatctgtcc
    32461 cctgatgatt attacccgca agctaaaaca aacatcatca atcattaaaa ctcataactt
    32521 tcaataacat aaaatcatca aaaaaatatt tgatgcctta tgtatctcaa ttttcaagac
    32581 cataaatttg tccctagtta actttaactt attgaaataa atataatatt cgtgcgtact
    32641 gatcctaatg tcacatcgca aaaattccgc ttcctcgctc actcagtcgc tacgctcctg
    32701 ccgttcggct gcggcgagcg gtatctcctt tctcaaaacc agagagattc agatcatatg
    32761 atccgttatt tgatcctttt tggatcttcc actaagaagc cctgaatcgc gctctgccgc
    32821 ttcgttcgat acaaccatga ggaaaaccat gcgaaatgaa aaaatcgctt aaaatgcgat
    32881 tcagagcgtt ttagggaggt tctgttagtt ctcctgcatt gcgcccgtag ttcgctaacg
    32941 ctcacacgcg cagtacagcg ccccgccatg ctgcaatgca ccagggcggg gtaaactcgc
    33001 ttgcgctcgc gctaactgcg gcattctgcg gcgcaaatca gcataatcat ggcctgctgg
    33061 tcagttgggc tttgcagggt gaagggatgg cctgtgcacc ctggtacgtt cgtcagcggc
    33121 tgcgccgcgc gcttcggggc gatgtggctc ctgtgctgcc ctggtatttt cgttcgcccc
    33181 ttccatccgc ttacgcggat taaaaaacgt gataacaatc acttatcgag taaaaaaacg
    33241 ggagaaaact tgcaaatacg acttaaaggt cgtattattg tttcatcgaa aggggaatgg
    33301 cccctctcac aatagcccag cagggcagga gattaaaaaa ataaatatcc aggaagcatt
    33361 aaacgttttt ggattatccg gcgaattaac tgaaaaagat atcaaagcag catacagaaa
    33421 agccgcttta aaatatcatc cagatcgtaa cccgttaggg gctgaactga tgaaagcggt
    33481 aaatgcagct tttgatgtat tgatggcaaa atattgataa aataaatcag ttccagagca
    33541 ctgatgaaca tgcacgatat aattacggtg atgacctgga aaagtattaa acgttctttc
    33601 tggtttatct ggtctggtat ttgaagtgat aggtaactgg tctggattag tggagaaacc
    33661 attacacata aggaaacttt aaaagaaatc gggtgtaaat gggcggcaaa gaaaaaacaa
    33721 tggttttcgt ccagacgaac ataaaagtta ctggaatcgt gaagaacaca cgatagaaga
    33781 aatccgcgca aaatacggta caaccggaca gcgcagggcg acagggtggc aacgcgtgga
    33841 aaccagagcg taaccagaac gggggcgaga agccccgata ttatagccag cccgtctttt
    33901 ggggcatcga acccaaaaag acgggaacag cagccacgta gcaaaaaggg aaacagatga
    33961 actctttttt gaacaatatc accctgtctt tgaagttgtc tgccgtatcc tggggaacgg
    34021 ctggcgcgtg aacaaacttg atgattgttc gtctcgtata aaactgacgt caccgcagtt
    34081 taaaaattac tctgtgcata ttcggatgga aaaagaccgc ttttctgtgg tggggagtgt
    34141 ggatagtcgt tcctggcgta gtccgcatca tgtttgcacg ttatccagaa acggaatccc
    34201 gttgatattg cagccgatat cgagcgaaaa attctggtaa atgctcgcag gaggtgttac
    34261 aggcgattga gtatgagaaa caccaggtgg aaaaaaagga cgaaattctg atcctgaaag
    34321 gtatgttatc gcaacttgtc cagcttgaaa gctggtatgg ggcattgaca ggctttaaag
    34381 ctgaaaacgg attgaacggt aaagtcaccg aacagggcga cagttatgat ttacagattc
    34441 ggggcttgag tatagatcaa cttgttaaaa ttacagggta tttgaaacag ttatgagaaa
    34501 aaataaaggt gatgtgactt attttcttga aaaagaaggt gacaattaca ggcttacaaa
    34561 aaggataaaa gccagaacaa atgttaaaat cgggaacaaa actacgaaaa ttacattgta
    34621 tgatgctgta ctgaatgaga atgaattaca acatattgat tttacgtgtg ccggattaag
    34681 ggaagacgat gagacgccag ttaagaattt aattaaggag tttatgttaa aatgaaaccc
    34741 gataatacac ctgaaaatgt aaaaaaatta cgtttaaaag caggattaac acaaaaggaa
    34801 tgcagtcata tttatggtgt tgggctaaga acctggcaga aaaagaggaa gttaatactc
    34861 aaaacagtca aagtctgtca ctggttgagt ttgagtttct tttgttactt gcaggagaac
    34921 atcctgaata cgtgctctgc aaaagggagt caaaataaaa tgacctgtga tggttttata
    34981 ttagtacctg gagttgcgct cgtagctcgc tgacgctcac acgcgcagta cagcgccccg
    35041 ccatgctgca atgcaccagg gcggggtaaa ctcgcttgcg ctcgcgctaa ctgcggca
//
