LOCUS       NZ_CP023900            34323 bp    DNA     circular CON 14-JUN-2024
DEFINITION  Escherichia coli strain FDAARGOS_433 plasmid unnamed6, complete
            sequence.
ACCESSION   NZ_CP023900
VERSION     NZ_CP023900.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN07312477
            Assembly: GCF_002589795.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 34323)
  AUTHORS   Croxen,M., Tallon,L., Sadzewicz,L., Ott,S., Zhao,X., Nagaraj,S.,
            Vavikolanu,K., Aluvathingal,J., Nadendla,S., Geyer,C. and Sichtig,H.
  TITLE     FDA dAtabase for Regulatory Grade micrObial Sequences (FDA-ARGOS):
            Supporting development and validation of Infectious Disease Dx tests
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 34323)
  AUTHORS   Croxen,M., Tallon,L., Sadzewicz,L., Ott,S., Zhao,X., Nagaraj,S.,
            Vavikolanu,K., Aluvathingal,J., Nadendla,S., Geyer,C. and Sichtig,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-OCT-2017) Center for Devices and Radiological Health,
            US Food and Drug Administration, 10903 New Hampshire Avenue, Silver
            Spring, MD 20993-0002, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: SMRT v. 2.3.0, HGAP v. 3, SPAdes v. 3.6.0
            Genome Coverage                   :: 696.335x
            Sequencing Technology             :: PacBio; Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002589795.1-RS_2024_06_14
            Annotation Date                   :: 06/14/2024 04:40:22
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,097
            CDSs (total)                      :: 4,972
            Genes (coding)                    :: 4,693
            CDSs (with protein)               :: 4,693
            Genes (RNA)                       :: 125
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 92
            ncRNAs                            :: 11
            Pseudo Genes (total)              :: 279
            CDSs (without protein)            :: 279
            Pseudo Genes (ambiguous residues) :: 0 of 279
            Pseudo Genes (frameshifted)       :: 87 of 279
            Pseudo Genes (incomplete)         :: 190 of 279
            Pseudo Genes (internal stop)      :: 46 of 279
            Pseudo Genes (multiple problems)  :: 39 of 279
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP023900.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..34323
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="FDAARGOS_433"
                     /isolation_source="Rectal"
                     /host="Homo sapiens"
                     /culture_collection="FDA:FDAARGOS_433"
                     /db_xref="taxon:562"
                     /plasmid="unnamed6"
                     /geo_loc_name="Canada: BC"
                     /collection_date="2015-12"
                     /collected_by="BC Centre for Disease Control"
     gene            complement(join(33328..34323,1..36))
                     /gene="repA"
                     /locus_tag="CRN16_RS25790"
                     /old_locus_tag="CRN16_25785"
     CDS             complement(join(33328..34323,1..36))
                     /gene="repA"
                     /locus_tag="CRN16_RS25790"
                     /old_locus_tag="CRN16_25785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907860.1"
                     /GO_process="GO:0006276 - plasmid maintenance [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid replication initiator RepA"
                     /protein_id="WP_023518831.1"
                     /translation="MAGLKNTPYNAVHWSQLAPEEQIRFWEDYEAGRATTFLVEPERKR
                     TKRRRGEHSTKPKCENPSWYRPELYKALSGQLGHAYNRLVKKDPVTGEQSLRMHMSLHP
                     FYVQKRTYAGRKYAFRPEKQRLLDAIWPVLVSFSDAGTHTVGMSVSRLAREISPKDSKG
                     KVIPELEVTVSRLSRLLAEQVRFGVLGVSEETLWDRETRQRLPRYVWITPAGWQMLGVD
                     MVKLHEQQQKRLRESEIRQQLIREGVLREDEDISVHAARKRWYLQRSQDALKHRRAKAA
                     ASKRARRLKKLPADQQIHEMAEYLRKRLPPDEAYFCSDDHLKRLAIRELRQLELTLAAP
                     PPH"
                     /name="repA"
     gene            993..>1151
                     /locus_tag="CRN16_RS28325"
                     /pseudo=""
     CDS             993..>1151
                     /locus_tag="CRN16_RS28325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000980235.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="ash family protein"
                     /name="ash family protein"
     gene            1189..1476
                     /locus_tag="CRN16_RS25810"
                     /old_locus_tag="CRN16_25805"
     CDS             1189..1476
                     /locus_tag="CRN16_RS25810"
                     /old_locus_tag="CRN16_25805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000074849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraA"
                     /protein_id="WP_000074855.1"
                     /translation="MSPQMIQKLPAITLLEGMFPELSTNQLKVCVFYAMGVPYDAIAQN
                     CRLSPETVRTYLKRSLKNLNLEGYDALRSAVLMRTFVFMISNTAKENEKM"
                     /name="conjugal transfer protein TraA"
     gene            1918..>2223
                     /locus_tag="CRN16_RS25820"
                     /old_locus_tag="CRN16_25815"
                     /pseudo=""
     CDS             1918..>2223
                     /locus_tag="CRN16_RS25820"
                     /old_locus_tag="CRN16_25815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001303319.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination NusG
                     family protein"
                     /name="transcription termination/antitermination NusG
                     family protein"
     gene            complement(2237..2934)
                     /locus_tag="CRN16_RS25825"
                     /old_locus_tag="CRN16_25820"
     CDS             complement(join(2237..2685,2685..2934))
                     /locus_tag="CRN16_RS25825"
                     /old_locus_tag="CRN16_25820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558260.1"
                     /ribosomal_slippage=""
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1-like element IS1B family transposase"
                     /protein_id="WP_095033700.1"
                     /translation="MASVSISCPSCSATDGVVRNGKSTAGHQRYLCSHCRKTWQLQFTY
                     TASQPGTHQKIIDMAMNGVGCRATARIMGVGLNTIFRHFKKLRPQSVTSRIQPGSDVIV
                     CAEMDEQWGYVGAKSRQRWLFYAYDRLRKTVVAHVFGERTMATLGRLMSLLSPFDVVIW
                     MTDGWPLYESRLKGKLHVISKRYTQRIERHNLNLRQHLARLGRKSLSFSKSVELHDKVI
                     GHYLNIKHYQ"
                     /name="IS1-like element IS1B family transposase"
     gene            complement(<2990..4147)
                     /locus_tag="CRN16_RS25835"
                     /old_locus_tag="CRN16_25830"
                     /pseudo=""
     CDS             complement(<2990..4147)
                     /locus_tag="CRN16_RS25835"
                     /old_locus_tag="CRN16_25830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_031587700.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISEcp1 family transposase"
                     /name="IS1380-like element ISEcp1 family transposase"
     gene            complement(4300..4674)
                     /locus_tag="CRN16_RS25840"
                     /old_locus_tag="CRN16_25835"
     CDS             complement(4300..4674)
                     /locus_tag="CRN16_RS25840"
                     /old_locus_tag="CRN16_25835"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_223349261.1"
                     /translation="MSQLKQPIFLKKIKKVINTIPGLEEQIFACRNKKRSDNPLLFIDR
                     KDEERILMSRLQSQQKNEELASKLESLFHGNELSSPHSILCFIYWRYTKKIYRLSEDII
                     SDVANTYVDNLDSTSVLQKA"
                     /name="hypothetical protein"
     gene            4995..5147
                     /locus_tag="CRN16_RS25845"
                     /old_locus_tag="CRN16_25840"
     CDS             4995..5147
                     /locus_tag="CRN16_RS25845"
                     /old_locus_tag="CRN16_25840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001618166.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hok/Gef family protein"
                     /protein_id="WP_001387489.1"
                     /translation="MPQRTFLMMLIVVCVTILCFVWMVRDSLCGLRLQQGNTVLVATLA
                     YEVKR"
                     /name="Hok/Gef family protein"
     gene            complement(5219..5470)
                     /locus_tag="CRN16_RS25850"
                     /old_locus_tag="CRN16_25845"
     CDS             complement(5219..5470)
                     /locus_tag="CRN16_RS25850"
                     /old_locus_tag="CRN16_25845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001291964.1"
                     /translation="MSEKWSKEFDSCFQVGSIEEIADALEKRSGSEENALAMLAMTAFT
                     LMTRRGICEMQNVAPDGKGIRLELIGFRENETIPDTLH"
                     /name="hypothetical protein"
     gene            5971..6066
                     /gene="dqlB"
                     /locus_tag="CRN16_RS28420"
     CDS             5971..6066
                     /gene="dqlB"
                     /locus_tag="CRN16_RS28420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DinQ-like type I toxin DqlB"
                     /protein_id="WP_000609148.1"
                     /translation="MINLLIIVLRAVVAVANALIAVLELIRELID"
                     /name="dqlB"
     gene            complement(6131..6307)
                     /locus_tag="CRN16_RS27805"
     CDS             complement(6131..6307)
                     /locus_tag="CRN16_RS27805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001054900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001054897.1"
                     /translation="MNLVDAFVKKVISEPYEEYGKWWIDVEYISWGVPGKTRLMFESKE
                     QALEVKEGYKFLT"
                     /name="hypothetical protein"
     gene            6699..6908
                     /locus_tag="CRN16_RS25860"
                     /old_locus_tag="CRN16_25855"
     CDS             6699..6908
                     /locus_tag="CRN16_RS25860"
                     /old_locus_tag="CRN16_25855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062602.1"
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="WP_000062603.1"
                     /translation="MSMPPAIANTFLFEMMKSKSKDVTLAAIYALGEGRCQAENITREL
                     HRLSQSDDMEIKIAAIKALGRIYR"
                     /name="HEAT repeat domain-containing protein"
     gene            complement(6980..>7078)
                     /locus_tag="CRN16_RS28330"
                     /pseudo=""
     CDS             complement(6980..>7078)
                     /locus_tag="CRN16_RS28330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001480010.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutE"
                     /name="ethanolamine utilization protein EutE"
     gene            7133..7830
                     /locus_tag="CRN16_RS25870"
                     /old_locus_tag="CRN16_25865"
     CDS             join(7133..7382,7382..7830)
                     /locus_tag="CRN16_RS25870"
                     /old_locus_tag="CRN16_25865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558260.1"
                     /ribosomal_slippage=""
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1-like element IS1B family transposase"
                     /protein_id="WP_095033700.1"
                     /translation="MASVSISCPSCSATDGVVRNGKSTAGHQRYLCSHCRKTWQLQFTY
                     TASQPGTHQKIIDMAMNGVGCRATARIMGVGLNTIFRHFKKLRPQSVTSRIQPGSDVIV
                     CAEMDEQWGYVGAKSRQRWLFYAYDRLRKTVVAHVFGERTMATLGRLMSLLSPFDVVIW
                     MTDGWPLYESRLKGKLHVISKRYTQRIERHNLNLRQHLARLGRKSLSFSKSVELHDKVI
                     GHYLNIKHYQ"
                     /name="IS1-like element IS1B family transposase"
     gene            <7846..7959
                     /locus_tag="CRN16_RS28335"
                     /pseudo=""
     CDS             <7846..7959
                     /locus_tag="CRN16_RS28335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_031587700.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            8283..9428
                     /locus_tag="CRN16_RS25875"
                     /old_locus_tag="CRN16_25870"
     CDS             8283..9428
                     /locus_tag="CRN16_RS25875"
                     /old_locus_tag="CRN16_25870"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extended-spectrum class C beta-lactamase CMY-42"
                     /protein_id="WP_039023136.1"
                     /translation="MMKKSLCCALLLTASFSTFAAAKTEQQIADIVNRTITPLMQEQAI
                     PGMAVAVIYQGKPYYFTWGKADIANNHPVTQQTLFELGSVSKTFNGVLGGDAIARGEIK
                     LSDPVTKYWPELTGKQWQGIRLLHLATYTAGGLPLQIPDDVRDKAALLHFYQNWQPQWT
                     PGAKRLYANSSIGLFGALAVKPSGMSYEEAMTRRVLQPLKLAHTWITVPQNEQKDYAWG
                     YREGKPVHSSPGQLDAEAYGVKSSVIDMARWVQANMDASHVQEKTLQQGIALAQSRYWR
                     IGDMYQGLGWEMLNWPLKADSIINGSDSKVALAALPAVEVNPPAPAVKASWVHKTGSTG
                     GFGSYVAFVPEKNLGIVMLANKSYPNPVRVEAAWRILEKLQ"
                     /name="extended-spectrum class C beta-lactamase CMY-42"
     gene            9522..10055
                     /locus_tag="CRN16_RS25880"
                     /old_locus_tag="CRN16_25875"
     CDS             9522..10055
                     /locus_tag="CRN16_RS25880"
                     /old_locus_tag="CRN16_25875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin family protein"
                     /protein_id="WP_001221666.1"
                     /translation="MRILPVVAAVTAAFLVVACSSPTPPKGVTVVNNFDAKRYLGTWYE
                     IARFDHRFERGLDKVTATYSLRDDGGINVINKGYNPDREMWQKTEGKAYFTGDPSRAAL
                     KVSFFGPFYGGYNVIALDREYRHALVCGPDRDYLWILSRTPTISDEMKQQMLAIATREG
                     FEVNKLIWVKQPGA"
                     /name="lipocalin family protein"
     gene            complement(10052..10369)
                     /gene="sugE"
                     /locus_tag="CRN16_RS25885"
                     /old_locus_tag="CRN16_25880"
     CDS             complement(10052..10369)
                     /gene="sugE"
                     /locus_tag="CRN16_RS25885"
                     /old_locus_tag="CRN16_25880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463202.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter SugE"
                     /protein_id="WP_000118520.1"
                     /translation="MSWIVLLIAGLLEVVWAIGLKYTHGFTRLTPSIITIAAMIVSIAM
                     LSWAMRTLPVGTAYAVWTGIGAVGAAITGILLLGESASPARLLSLGLIVAGIIGLKLST
                     H"
                     /name="sugE"
     gene            10565..11347
                     /gene="finQ"
                     /locus_tag="CRN16_RS25890"
                     /old_locus_tag="CRN16_25885"
     CDS             10565..11347
                     /gene="finQ"
                     /locus_tag="CRN16_RS25890"
                     /old_locus_tag="CRN16_25885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_023063753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein FinQ"
                     /protein_id="WP_023063753.1"
                     /translation="MMKGFLKPESRDNIPAQILKELPSWSIYVSAENLHTILPTSYPIH
                     GFFFYPFLDNNGNIIRLFIIDDLKQSQGTTGLKEKNVDVVNNIIRIKDSREGLLDSRKM
                     ECIDGEVVVTVNEKLKDFRDREFNLLNAQISMVLYICSQINDIKEKNQFKRSEKHKKHV
                     HTHHELPAQNIREWDVGIRMGQAIRQYRQAEPTGKERTTIGSKRPHIRRGHWHTYWTGS
                     KKPELAHERKPRLIWLPPVPVNLEDVNKLPVVITPIDK"
                     /name="finQ"
     gene            11654..>12553
                     /gene="trbA"
                     /locus_tag="CRN16_RS25895"
                     /old_locus_tag="CRN16_25890"
                     /pseudo=""
     CDS             11654..>12553
                     /gene="trbA"
                     /locus_tag="CRN16_RS25895"
                     /old_locus_tag="CRN16_25890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000121273.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IncI1-type conjugal transfer protein TrbA"
                     /name="trbA"
     gene            complement(12621..13402)
                     /gene="istB"
                     /locus_tag="CRN16_RS25900"
                     /old_locus_tag="CRN16_25895"
                     /pseudo=""
     CDS             complement(12621..13402)
                     /gene="istB"
                     /locus_tag="CRN16_RS25900"
                     /old_locus_tag="CRN16_25895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858162.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element IS100kyp family helper ATPase
                     IstB"
                     /name="istB"
     gene            complement(13399..14421)
                     /gene="istA"
                     /locus_tag="CRN16_RS25905"
                     /old_locus_tag="CRN16_25900"
     CDS             complement(13399..14421)
                     /gene="istA"
                     /locus_tag="CRN16_RS25905"
                     /old_locus_tag="CRN16_25900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627495.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element IS100 family transposase"
                     /protein_id="WP_000255956.1"
                     /translation="MVTFETVMEIKILHKQGMSSRAIARELGISRNTVKRYLQAKSEPP
                     KYTPRPAVASLLDEYRDYIRQRIADAHPYKIPATVIAREIRDQGYRGGMTILRGFIRSL
                     SVPQEQEPAVRFETEPGRQMQVDWGTMRNGRSPLHVFVAVLGYSRMLYIEFTDNMRYDT
                     LETCHRNAFRFFGGVPREVLYDNMKTVVLQRDAYQTGQHRFHPSLWQFGKEMGFSPRLC
                     RPFRAQTKGKVERMVQYTRNSFYIPLMTRLRPMGITVDVETANRHGLRWLHDVANQRKH
                     ETIQARPCDRWLEEQQSMLALPPEKKEYDVHPGENLVNFDKHPLHHPLSIYDSFCRGVA
                     "
                     /name="istA"
     gene            complement(<14503..14871)
                     /locus_tag="CRN16_RS25910"
                     /old_locus_tag="CRN16_25905"
                     /pseudo=""
     CDS             complement(<14503..14871)
                     /locus_tag="CRN16_RS25910"
                     /old_locus_tag="CRN16_25905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001387486.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /name="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            complement(14882..15214)
                     /gene="nikA"
                     /locus_tag="CRN16_RS25915"
                     /old_locus_tag="CRN16_25910"
     CDS             complement(14882..15214)
                     /gene="nikA"
                     /locus_tag="CRN16_RS25915"
                     /old_locus_tag="CRN16_25910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IncI1-type relaxosome accessory protein NikA"
                     /protein_id="WP_001283947.1"
                     /translation="MSDSAVRKKSEVRQKTVVRTLRFSPVEDETIRKKAEDSGLTVSAY
                     IRNAALNKRINSRTDDAFLKELMRLGRMQKHLFVQGKRTGDKEYAEVLVAITELTNTLR
                     KQLMEG"
                     /name="nikA"
     gene            15448..15783
                     /locus_tag="CRN16_RS25920"
                     /old_locus_tag="CRN16_25915"
     CDS             15448..15783
                     /locus_tag="CRN16_RS25920"
                     /old_locus_tag="CRN16_25915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_021529212.1"
                     /translation="MASKKFYSDDDIQLAKAALSELPDLTAQRKTLRDFLDAIRDDIII
                     LVRTKGYTLADVRDTLKNAGYEVGEKALRDIIREAESKKTSRRSSSKTAPKKTDSGRKD
                     GIDMNNN"
                     /name="hypothetical protein"
     gene            complement(15870..16718)
                     /locus_tag="CRN16_RS25925"
                     /old_locus_tag="CRN16_25920"
     CDS             complement(15870..16718)
                     /locus_tag="CRN16_RS25925"
                     /old_locus_tag="CRN16_25920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001401764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4942 domain-containing protein"
                     /protein_id="WP_001599394.1"
                     /translation="MNQTLPTADLNTAGTTDVIPSVAIDRIIAQRNEGIALFMQAMECL
                     ATARKILLDASGDIFLYGFEDCVTDSVRRMDKPEEAKRNITRLADRKIWDRLMTDTGMY
                     TFMSSCQRDEWNSQLMSDTCPEITLDNVLATFRHLNASKMQTFEQGLIDVYRKLSWDYR
                     TNNPCRLGKKIIIENLLYRWSNGRVTLDCSGREALDDLVRPFYLLEGRNVPDFRNSIGA
                     QYGEFLGNGDNVGKLLEGEYFTVRGYQKGTVHIVFKRSDLVEKLNDIIARHYPGALPPR
                     V"
                     /name="DUF4942 domain-containing protein"
     gene            17067..17264
                     /locus_tag="CRN16_RS28510"
                     /old_locus_tag="CRN16_25930"
     CDS             17067..17264
                     /locus_tag="CRN16_RS28510"
                     /old_locus_tag="CRN16_25930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001753860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001161107.1"
                     /translation="MQGAPHPARLKKNDGTTMACGGHWHTTPAQVKTEKTARHLQPKKV
                     KFLHFFSLIYRADLAIVMIK"
                     /name="hypothetical protein"
     gene            17298..17549
                     /locus_tag="CRN16_RS25940"
                     /old_locus_tag="CRN16_25935"
     CDS             17298..17549
                     /locus_tag="CRN16_RS25940"
                     /old_locus_tag="CRN16_25935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003980153.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000148285.1"
                     /translation="MTGWELRIWRKSMLWSREKAAREFGVTQRTWHAWENAEQVDVTVW
                     RTTQALSVRDLLPHMQGMRKADIIRRLENELGETAEDV"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(17580..17786)
                     /locus_tag="CRN16_RS25945"
                     /old_locus_tag="CRN16_25940"
     CDS             complement(17580..17786)
                     /locus_tag="CRN16_RS25945"
                     /old_locus_tag="CRN16_25940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000150315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000150314.1"
                     /translation="MTIAERLIQKGFDEGFDEGFKEGFKKGALEVAREAACRLRDMGWT
                     PERIQEAAGLSGEELKKLFPDEQ"
                     /name="hypothetical protein"
     gene            complement(17848..18750)
                     /locus_tag="CRN16_RS25950"
                     /old_locus_tag="CRN16_25945"
     CDS             complement(17848..18750)
                     /locus_tag="CRN16_RS25950"
                     /old_locus_tag="CRN16_25945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="WP_011264057.1"
                     /translation="MSKKKNTTTPTPHDAVFRSFLANPDVARDFLELHLPAEYRQLCDL
                     STLKLEPATFVEPDLHQYASDILWSVKTTGGKDGYVYTLIEHQSTENLYMPFRMLRYSV
                     AAMQRHLEQHKTLPLVIPVLFYHGERSPYPYSMNWLDCFENPALAAKIYTKPFPLVDIT
                     VVDDNEIMNHRRMAALTLLMKHIRHRDMMELLDKLPQVMVEISDEQVRVLIHYIVNAGD
                     SVSPEFMRALAERLPQHEDKLMTIAERLEQKGRQEGRMEGALEKALAIACQLQKMGMTP
                     EQIKQATGLSDDELKKIIH"
                     /name="Rpn family recombination-promoting nuclease/putative
                     transposase"
     gene            complement(18747..19136)
                     /locus_tag="CRN16_RS25955"
                     /old_locus_tag="CRN16_25950"
     CDS             complement(18747..19136)
                     /locus_tag="CRN16_RS25955"
                     /old_locus_tag="CRN16_25950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000833767.1"
                     /translation="MKSCFDTDKAFHMSFDEVTFNADRIRSKLELLSEELMPRCGLVYE
                     LYQRRLSAAIDNFVATLPTEQHLLVLELAREEFDYLSAEEIAEEIRRDSERGYCCHGFE
                     RNCCPLGCGDLGDDCCDAADLMEEP"
                     /name="hypothetical protein"
     gene            complement(19313..19579)
                     /locus_tag="CRN16_RS25960"
                     /old_locus_tag="CRN16_25955"
     CDS             complement(19313..19579)
                     /locus_tag="CRN16_RS25960"
                     /old_locus_tag="CRN16_25955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000804663.1"
                     /translation="MKPSIIFATAEYVKRLREECLRENKPLHRHTRFRRQELAQDEINP
                     DVLAMSGHIARRCSEQKRVRIPAMKVSEWGHLLRALEIERVCH"
                     /name="hypothetical protein"
     gene            complement(19673..20107)
                     /locus_tag="CRN16_RS25965"
                     /old_locus_tag="CRN16_25960"
     CDS             complement(19673..20107)
                     /locus_tag="CRN16_RS25965"
                     /old_locus_tag="CRN16_25960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000218847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000218858.1"
                     /translation="MTVSSTISVFCRDGVFRTVYCHLHGEPTWNGRILHTHYATGQQAE
                     ALVEHGDIRCLGPRCDKPAGHTLQNPVDGVTAYYGRDSGFRMDSEAREYRSFMEAIATE
                     STEEVRFHYVFIDGYWKVMYRTPEGWKMKALALALRRCPK"
                     /name="hypothetical protein"
     gene            complement(20836..21336)
                     /locus_tag="CRN16_RS25980"
                     /old_locus_tag="CRN16_25975"
     CDS             complement(20836..21336)
                     /locus_tag="CRN16_RS25980"
                     /old_locus_tag="CRN16_25975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000117633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="WP_000117626.1"
                     /translation="MSVVAPAVYVGTWHKYNCGSIAGRWFDLTTFDDERDFFAACRALH
                     QDEADPELMFQDYEGFPGNMASECHINWAWVEGFRRARDEGCEEAYRLWVDDTGETDFD
                     TFRDAWWGEADSEEAFAVEFASDTGLLADVPETVALYFDYEAYARDLFLDSFTFIDGHV
                     FRR"
                     /name="antirestriction protein ArdA"
     gene            complement(21798..22394)
                     /locus_tag="CRN16_RS25990"
                     /old_locus_tag="CRN16_25985"
     CDS             complement(21798..22394)
                     /locus_tag="CRN16_RS25990"
                     /old_locus_tag="CRN16_25985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000978013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000977995.1"
                     /translation="MMKSDEKYQVPAWMRPLLPLLCNTGGNDPEELLNDTETTASANVV
                     RYVLIVAVRSQVDLLQLLYRKGLLRTEIPGGFSPEEAQALLDNLVRSHISKALSGERMA
                     ARDRNADLAWIGQQLVDAAWFVRATLEAHGMSVGNESPPAPPETMPDIQTRELVMLIKR
                     LASSLKAVKPDSCVVREAQDWLRDRKLVDITDILR"
                     /name="hypothetical protein"
     gene            complement(22391..>22744)
                     /locus_tag="CRN16_RS27935"
                     /pseudo=""
     CDS             complement(22391..>22744)
                     /locus_tag="CRN16_RS27935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001584594.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid SOS inhibition protein A"
                     /name="plasmid SOS inhibition protein A"
     gene            complement(<22739..>23632)
                     /locus_tag="CRN16_RS27810"
                     /pseudo=""
     CDS             complement(<22739..>23632)
                     /locus_tag="CRN16_RS27810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052657.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            complement(23815..25716)
                     /gene="ltrA"
                     /locus_tag="CRN16_RS26000"
                     /old_locus_tag="CRN16_25995"
     CDS             complement(23815..25716)
                     /gene="ltrA"
                     /locus_tag="CRN16_RS26000"
                     /old_locus_tag="CRN16_25995"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936286.1"
                     /GO_function="GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="WP_000936285.1"
                     /translation="MLPDELEKRLDGIEDASKKGYPVRNLYKIACEPGLWLQAYVNIRA
                     NAGALTQGVSTDTIDGFSIERAEKLAKTLRSREYVAKPVRRVQIPKKDGKTRPLGIPGG
                     DDKLAQEVARIILERVYEPVFSEHSHGFRPKRSCETALRSIRPVWNGVKWIVDVDIKGF
                     FDNIPHKLLLNTLAEKIKDKNFLKLIEQWLKAGYVDNWKYHRSYSGTPQGGIISPLLAN
                     IYLDKLDRFVEQNLIPAYTSGTKRRANPDMNRLAHKIHKLRKKVDGMATDSESEKEAIK
                     KEIERLLEEKRSIPSQVMNDPNFRRMYYVRYADDFVIGVIGSKKDAEHISRQVRNFITT
                     SLGLEVNEAKTRIRHISEGVNFLGYEIRQADAKKLLKQKMQGRHALRRSTTGIVQLFVP
                     DNIAAKFCHQKKYGCYENVKAVHRSSLQNLSEAEIVLTFNAEMRGLANYYSLALDMKYK
                     LSKLYFIWQISLFKTLANKRRSSVNKVAKSLRQNNGDLAITVQAKNGSRKIEVFKLKHV
                     NRNRTTIVDTEPRTAHITTRTTEIMRRLGARICEYCAKTGRCEVHHVRKLKDLKKGRKA
                     GYKPSLWQLMMIARRRKTMILCASCHDKLHSGKLPDLRQEKGRILLQPPVSSGDSAK"
                     /name="ltrA"
     gene            26074..26493
                     /gene="umuD"
                     /locus_tag="CRN16_RS26005"
                     /old_locus_tag="CRN16_26000"
     CDS             26074..26493
                     /gene="umuD"
                     /locus_tag="CRN16_RS26005"
                     /old_locus_tag="CRN16_26000"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000457137.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translesion error-prone DNA polymerase V
                     autoproteolytic subunit"
                     /protein_id="WP_057109540.1"
                     /translation="MVSCFPHRSRLQQTQFADRCQAGFPSPATDYAEQELDLNSYCISR
                     PAATFFLRASGESMNQAGVQNGDLLVVDRAEKPQHGDIVIAEIDGEFTVKRLLLRPRPA
                     LEPVSDSPEFRTLYPENICIFGVVTHVIHRTRELR"
                     /name="umuD"
     gene            26493..27764
                     /locus_tag="CRN16_RS26010"
                     /old_locus_tag="CRN16_26005"
     CDS             26493..27764
                     /locus_tag="CRN16_RS26010"
                     /old_locus_tag="CRN16_26005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001744069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="WP_001703910.1"
                     /translation="MFALADINSFYASCEKVFRPDLRNEPVIVLSNNDGCVIARSPEAK
                     ALGIKMGQPWFQVRQMRLEKKIHVFSSNYALYHSMSQRVMAVLESLSPAVEPYSIDEMF
                     IDLRGINHCISPDFFGHQLREQVKSWTGLTMGVGIAPTKTLAKSAQWATKQWPQFSGVV
                     ALTAENRNRTLKLLGLQPVGEVWGVGRRLTEKLNALGINTALQLAQANTAFIRKNFSVI
                     LERTVRELNGESCISLEEAPPAKQQIVCSRSFGERITDKDAMHQAVVQYAERAAEKLRG
                     ERQYCRQVTTFVRTSPFAVKEPCYSNAAVEKLPLPTQDSRDIIAAACRALNHVWREGYR
                     YMKAGVMLADFTPSGIAQPGLFDEIQPRKNSEKLMKTLDELNQSGKGTVWFAGRGTAPE
                     WQMKREMLSPAYTTRWTDLPVAQL"
                     /name="Y-family DNA polymerase"
     gene            27952..28578
                     /locus_tag="CRN16_RS26015"
                     /old_locus_tag="CRN16_26010"
     CDS             27952..28578
                     /locus_tag="CRN16_RS26015"
                     /old_locus_tag="CRN16_26010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010260829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family plasmid-partitioning AAA ATPase"
                     /protein_id="WP_000587689.1"
                     /translation="MIIVLGSQKGGVGKSTLAVSIAAYLMSLGNRVIIVDADDQKSVLT
                     WYNNRPEDLPHIPVTGATGNIKAMLKEHEKSYDFVIADCAGRDSAEMRSGLMAADVFIS
                     PLRPSQMDLDVVPHTCSVFTAAKDFNEDVRGYLVLNMTPTNMFVNEANEAAEVLKDYPE
                     MHLANSRVCDRKAHRDAWAESMTIFETQNDKAQQEIEALVKEVIL"
                     /name="ParA family plasmid-partitioning AAA ATPase"
     gene            28575..28877
                     /locus_tag="CRN16_RS27815"
     CDS             28575..28877
                     /locus_tag="CRN16_RS27815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001245884.1"
                     /translation="MRNRANTSPRDEAAFINGGTAGLDNTKKSSDKSSVVSKAKPVSIS
                     FFEENLKDIDALITAEMVSGKGRVNRSDVVRAAVEALKTLSKTEVSRLIAEVKQR"
                     /name="hypothetical protein"
     gene            complement(29392..30738)
                     /gene="yagA"
                     /locus_tag="CRN16_RS26025"
                     /old_locus_tag="CRN16_26020"
     CDS             complement(29392..30738)
                     /gene="yagA"
                     /locus_tag="CRN16_RS26025"
                     /old_locus_tag="CRN16_26020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001132032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YagA"
                     /protein_id="WP_039052405.1"
                     /translation="MPMILVKKNPRGKVIRELSSEEETAVKTVCGLKKPATMAQHNLAN
                     DLLREMREYDAWLQCDCIPGDSPAMNFAALKNNTGTLYLSSFNHEHAPECPMYRQLSGN
                     EEETSFGASRHPVSTRINYRNFLPPDDSNSVIRLQTRSAYHNGERSSVRKKRPRLGRLL
                     LSLIEDAGLNKLDSLANPRIRTNYRECLDAIRQVTLQQEYIRGRSLSEIIHFRPGMSER
                     SQERLMETLENSERHWPARRKHMFFQIFMAQHICRDAVEIHWANGNIQVFRPVRGISIN
                     GEAQGGIRPPYWVILAFCRSADGRIICSEGYAHALYQLTCPVPVDSKLERNTLTALLNV
                     ASWLKRKPGTPELSLERPLFDTEVYVNGEKKYVLPDFIVTAMAPDGKTARVVIETMGYE
                     DSDYCARKSRQHTGMKQIGVLHTDPPKWLDNDHPPFEKHMYGVFMHLRY"
                     /name="yagA"
     gene            31092..31694
                     /locus_tag="CRN16_RS26035"
                     /old_locus_tag="CRN16_26030"
     CDS             31092..31694
                     /locus_tag="CRN16_RS26035"
                     /old_locus_tag="CRN16_26030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001703912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ProQ/FINO family protein"
                     /protein_id="WP_001703912.1"
                     /translation="MEKNQEERKIPVIVVKKRRTFSLPSLSEKTDIIESAFTEQAAESA
                     PVGINSSAVETHIPEAPARKKKKKKRRFPRPSHWTREYTHECVEKIKILFPHLRAEGGG
                     FIPLKIGINNDISAFLAEHPETELTMDEWLCAVSCITSRRVYLQRTAVAGVPRYGLDGH
                     PKGQVSESEAQSAGRRLVTLEQKLLRMQAQQENISGQ"
                     /name="ProQ/FINO family protein"
     gene            31750..32259
                     /locus_tag="CRN16_RS26040"
                     /old_locus_tag="CRN16_26035"
     CDS             31750..32259
                     /locus_tag="CRN16_RS26040"
                     /old_locus_tag="CRN16_26035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_012783913.1"
                     /translation="MSKSGAEKIQFILNNHEQAYRRLKPVYTFLELASWISVVLLIIYL
                     SGKNHVLTAAFLCFAWTAFWVLFLLHYFPKVFSILDRQSLLNLMEATKDSPDVKQELLN
                     RLFSGKRMTGRDEMDICRLLRKNEEEKIRQSELNIIRNFIDEQQLTNSDIPKKSTVPNE
                     DKKGIR"
                     /name="hypothetical protein"
     gene            complement(32492..32632)
                     /locus_tag="CRN16_RS27820"
     CDS             complement(32492..32632)
                     /locus_tag="CRN16_RS27820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004031751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_032072206.1"
                     /translation="MAENGYGLAGLGMGKVKSISPYRLTPGFGGFTPVSYATTECRLPC
                     R"
                     /name="hypothetical protein"
     ARG             8284..9425
                     /name="blaCMY-42"
                     /gene="blaCMY-42"
                     /gene_name="extended-spectrum class C beta-lactamase
                     CMY-42"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     Typing          15242..15333
                     /name="MOBP"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="4.37e-41"
     Typing          complement(33329..34323)
                     /name="IncI-gamma/K1"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(14540..14871)
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="97.297"
                     /coverage="88.0"
                     /evalue="2.5399999999999997e-68"
ORIGIN
        1 tactgcgtta tatggagtat tcttcagacc tgccacaagc tgtcgcttat ggcggagcga
       61 ttgtgccgtg tatttataca ctgcacaggg ttgaatctct ggtacggttt cattatactt
      121 tacccgtatt ctgtgaggcc cccataatct ttctccgtcc cgccaagttc gtcgaaagat
      181 tgtgggggtt ttccttttat ggcttccgga acatcttcgg tcttctgact tactgcccgt
      241 aaatgccatc tctcctgaat gccttatggc gcattctgcc gtccggcttt cgccgctttg
      301 ctccacagag tgccaccctc tgcgcagcta ataacaaccg aaatataccc gctttacgtt
      361 aatttgaaaa gcattacaac gatctcttct cttccagtgc ctcctcaccg atacctctaa
      421 tgagttaatc ttgacctgcg tcaaaaaaat aaaatctatt tttaaaagca gatttttctg
      481 ctttagatcc ttcttttgga ttaaaagatc gacttttgtt ctactcacga tcatttatct
      541 tacaaccgat caacctaaca gaataatatt ctgttttaag acaattaaac gatctaaaaa
      601 acctttaaaa aatcattttg tagatcattc gattgtaaat agaatgattc ttagataata
      661 aaaccatttg ttacacagcc cgccaattgt gtaacaacag cctctacaag agcatatttg
      721 ttcatatgtt cgtcagaact gcggattgtc tggacgaggg tcagacaccg tttcgtgcat
      781 atggaccagc atgttcgaac gccacaaagc agaagcatca tgcctggatc gcttcggcgc
      841 ggagcgttaa gttttgacgc ttttttgtat gttttttaag cggttagttg actcggtacg
      901 ttatactaag taccctttac tggtcacagg caaaactgtg atcgggcgta ggaacccgcg
      961 tagtcatcgt cggcgcagaa gttaatttct tcatttggcg tcgttttttg ccataccata
     1021 aagacaggaa cttgtatttc ttgtcgtcat ctatggtagc tcaggcgggg caggcattag
     1081 cctggccggt ttccgatgac gccggtattc ctacccccgt ctgggctatc accaatgagc
     1141 gtaggaactc ggtgatagcg ttttttgttg tcatcggaga cctttgctat gtcacctcaa
     1201 atgatacaga aactcccggc catcactctg ttggaaggca tgtttcccga gctatcaaca
     1261 aaccagctta aagtctgcgt tttttacgca atgggtgttc cttacgacgc cattgctcag
     1321 aactgtcggc tttctcccga aacggtacga acctacctga agcgaagcct gaagaactta
     1381 aatctggaag gatatgatgc acttcgctct gctgtgctga tgcgaacgtt cgttttcatg
     1441 attagcaata cagctaaaga aaacgaaaaa atgtgaacag gtgtccccat taaaggggac
     1501 actttcatgg aaattgcatt ttgcacttta caggcgctcc caaattgata aacataaaca
     1561 ccaagcacaa gttactttaa taaagcaaat cacttcagac ggtgtcccaa ttatttgtat
     1621 ctggctcatg cccgatatat ggcgacctta ctctgaactg acgtgctgat gttttatttc
     1681 gcgtatcacg atactgtgcc actgtattgc tgatattagt gcttagccgt tctttatctg
     1741 tgagttcgcc aaatcaccga tacagaacgt actagagtct gctggttata tgcctgtcag
     1801 aactgcagtt tatccagata tgggctggac actgcttcag acatatgatt tagcatattc
     1861 gcctgacatc gcaaaatcgt ccatcatgga tcggttttgc gcggagcgtt gaacttcgtg
     1921 aatatagaac acctgaataa ccggaactgg tatcttgcgc aatataatac agccggcaaa
     1981 aacagagaat ctttattctc atggctgaat gagcaaaacg tcgtaccatg gactccatta
     2041 ataacaagaa agataagacg ggcagactcc aggtgctgtc accgtgaaag aatattcgct
     2101 atttttccag ggtacttttt tattctggct aattttgaca ttcaaccagt atcggcatta
     2161 cgtcgccata gcgccttcat tgatttcgtg aagtttggcg gtgaaataaa acccgtcaat
     2221 aggtaatgac tccaacttat tgatagtgtt ttatgttcag ataatgcccg atgactttgt
     2281 catgcagctc caccgatttt gagaacgaca gcgacttccg tcccagccgt gccaggtgct
     2341 gcctcagatt caggttatgc cgctcaattc gctgcgtata tcgcttgctg attacgtgca
     2401 gctttccctt caggcgggat tcatacagcg gccagccatc cgtcatccat atcaccacgt
     2461 caaagggtga cagcaggctc ataagacgcc ccagtgtcgc catagtgcgt tcaccgaata
     2521 cgtgcgcaac aaccgtcttc cggagcctgt catacgcgta aaacagccag cgctggcgcg
     2581 atttagcccc gacgtatccc cactgttcgt ccatttccgc gcagacgatg acgtcactgc
     2641 ccggctgtat gcgcgaggtt accgactgcg gcctgagttt tttaaatggc ggaaaatcgt
     2701 gttgaggcca acgcccataa tgcgggcggt tgcccggcat ccaacgccat tcatggccat
     2761 atcaatgatt ttctggtgcg taccgggttg agaagcggtg taagtgaact gcagttgcca
     2821 tgttttacgg cagtgagagc agagatagcg ctgatgtccg gcggtgcttt tgccgttacg
     2881 caccaccccg tcagtagctg aacaggaggg acagctgata gaaacagaag ccactggagc
     2941 acctcaaaaa caccatcata cactaaatca gtaagttggc agcatcaccc ttcaaacgaa
     3001 aggtctttat ttgctgtctg tattctgaag agtccaagga atcaaacttg aacaacaaaa
     3061 ataggttata tgaaagcatc atcatttgaa acacggcttc attcgcccaa aatgacttta
     3121 gcaagagatg acccaccgcc atgtcgtatt tggcttcttt gatatagttt tcagcattac
     3181 cacgcttttc atagtatata actacttttt cagaaagcaa ggtagtattt gttacaaaga
     3241 aaaagtagtc gtattcggaa ccttctaaaa gtgataattg tgctctttct ttttctggtt
     3301 tcagtacgcg agatacgaca aatcttctgt ctttttccca tttaactaat tttgtataca
     3361 gttctgtagt ttctctacct tcttctcctt taacgaatac aattgatgaa ttcgttgctt
     3421 gtgaggtgag tgtagaataa cttttggctt taattaaata tttgcatcca agagattcta
     3481 tcgtttcgat aattttttca tcaaagtagc cactatccat tcgaaataaa atttctaaat
     3541 cgtctgattt gatgttagca acaatttctt tgatcatttc cgcagcaccg tttgcagtgt
     3601 aagtattgcc acttcttaca aatccggtaa catatgcttt taattcgtcg caaaatgcaa
     3661 attggatatt gtagcatcgg tttcccagtt tcttaggatt atatcctttt gacgcacctt
     3721 cttgatgacc ttctacgtta attacactac tatcaatatc aatcgtaatg gatgtcaatt
     3781 tacttttagt gagcagtttt ttaaagactt taaaattaat gtctctaaac atttgggttg
     3841 tcttgaagtt gaagtttcct agaaaccgtg acactgtttc aggttctttt acggaaatat
     3901 caaactcgtt gacgagggga tcattttgaa gtagctttag acgttctaac ttatcaatgc
     3961 caatgaagtg accgcagagc atggtcttta tatgattcat cttgatttta tttgttgagt
     4021 cattatcaaa tacgaggtca ttttcaataa aatcaaaaat cccattgctt tttgcattct
     4081 caaggagcag aaaaagacct gcatttgatg ttagattctt agctttgaaa tcaattttat
     4141 taatcataat tagaacccct ttttactact tttcttacta ttattttacc atatatcgag
     4201 tcataaaagc tgataattta acatattttt gagcactttt ctttcaccca atgggtgaaa
     4261 gctgaatttc gaaggaatgc atatttatca aggctttgat tatgcttttt gaagtactga
     4321 cgtagaatct aggttatcaa cataggtgtt agccacatca ctgatgatgt cctcgcttag
     4381 gcgataaatt ttctttgtat agcgccagta tataaaacac aaaatactgt gtggtgacga
     4441 taattcgttt ccatgaaata aagattctag tttagaagcc agttcttcat ttttttgttg
     4501 gctctggaga cgactcatta gtatgcgttc ttcatctttt ctgtcgataa ataataatgg
     4561 attgtcgctg cgttttttat ttcggcatgc aaagatttgc tcttcaagcc cagggattgt
     4621 gttgatgact ttttttatct ttttcaggaa aataggttgt tttaactgcg acatttccat
     4681 ctcctaaggg gattctttta ttaactaaaa tcagcataac atgcgttgtt gtgaagtaga
     4741 gaaccatgta ttgggttggt tgttaacttc aaaaacaacg ctgaatcatt caaataataa
     4801 aaggattgtt acagatacga aagtcgttag aatagctgcg ggcgcttgag gctgtatgcc
     4861 gaaagcgttt tgtggacggt atacagcaga aagcccctgg agattttttt atcaatcaac
     4921 caagggctct actgtaatgc ctcaacaaca ttatagtagc ccgataaccg ccggaaggca
     4981 atggaggggc tatgatgcca cagcgaacgt ttttaatgat gttaatcgtc gtctgtgtga
     5041 cgattctgtg ttttgtctgg atggtgaggg attcgctttg cggactccgg ctccagcagg
     5101 gaaacacagt gcttgtggca acgttagcct acgaagttaa acgttaacgg gcaacacggc
     5161 ggcaggtttt ctgccgccgc tttgttgcga aggctgacct cattgcgccc tttcttcttc
     5221 aatgaagcgt atctggtatt gtttcatttt ccctgaagcc gattagctcc agccgaatgc
     5281 ctttgccatc gggggccacg ttctgcattt cgcagatacc acgtcgggtc atgagtgtga
     5341 aggctgtcat tgccagcatg gctaacgcgt tttcctcgct tccgctgcgt ttctcgagag
     5401 catcggcaat ttcttctatg ctccccacct gaaagcaaga gtcgaattct ttactccact
     5461 tttctgacat cggattttct ctctgtattt atgggtagtt atcgaactga atgtgccagt
     5521 tttttcagga gacggcaaag ttgagatgat tggttctgat tcaaagcatg agtttccccg
     5581 gtgtgacggg catgtcgggc ggattttgag aaacaacaga tgtaaaaaaa ccgactggtg
     5641 aggtcggttt ttttactgtt ccgttacaga gtgggtggct ctggtcggaa aagaactgtc
     5701 tataactgac ttgtagatag tacgtctgga attatatttc tgcaagtact ggataagtgt
     5761 atactcggca tgtcagctct gaggcatgtt ctgtccgaca tattgttcag cgggaagaac
     5821 aggttgcaag tcctggccaa aacatcaggt ggtgctggtt ttggtgctct ggtcggagaa
     5881 gaactgtcta taactgacac tatagaaacc gttgtgacag gcagtgtaag agcgaacaac
     5941 ggggttcttt ctccagtgat ggagaagcgg atgattaatc tgttaatcat cgttctcagg
     6001 gcagtagttg ccgttgcaaa cgcgctgatt gctgttctgg aactgatccg ggaacttatc
     6061 gactgataag cctggaaacg taactaaggg cagggagtta ccgcttcctg ccctttaaca
     6121 aaaagagatc tcacgttaaa aatttgtacc cttctttaac ttccagtgcc tgctcctttg
     6181 actcaaacat cagtcttgtt ttcccgggaa caccccatga aatgtattca acatctatcc
     6241 accattttcc atattcttca tatggctcgg atattacttt tttgacaaag gcgtctacca
     6301 gattcattgt tttttccttt ttgtgttgaa aataattaat gccagagcac agcgaaaata
     6361 atgaatgcgc tggctgtgat aattgcgatt ttctcccata tgatattttt ctcatggggg
     6421 tttctacgga gattatttct tcgcattgag ataccggtat tcatgtttta tcttggattt
     6481 ttgttttgtt gtctgtctgg caggctgttc tgcgcccgtt tgtgacaagg ttagcttatg
     6541 gggttaaatg gtcacggaca tcatgcggac ggttccctgt cacatgccat ctggtttttt
     6601 cattcaaatt gagagatatt gctaagttga gtcgcttgcg atagtggact cctgtttgca
     6661 agtgagtgcc attgtttatt tcatgaagag gattgattat gagcatgcct cctgcgatag
     6721 ctaatacttt cttgtttgaa atgatgaaga gtaaatcaaa agacgttaca cttgctgcga
     6781 tctatgcatt aggtgaaggc cggtgtcagg cggagaacat tactcgtgaa ttacatagat
     6841 tgagtcaaag tgatgatatg gaaataaaaa ttgctgcgat taaagcactt ggtcgaattt
     6901 atcggtaacg gcataagtta tctgttgtaa tgaacaaaag ccggctcatt tgaaccggct
     6961 gttatggagg gagcttatct taaaatactt cggctacagg tatgcctgca atctgctccc
     7021 actccttacg cttttcctga atcaggcgag gaaagtcgac agggtaatca tatcctcggt
     7081 gatgctgcca acttactgat ttagtgtatg atggtgtttt tgaggtgctc cagtggcttc
     7141 tgtttctatc agctgtccct cctgttcagc tactgacggg gtggtgcgta acggcaaaag
     7201 caccgccgga catcagcgct atctctgctc tcactgccgt aaaacatggc aactgcagtt
     7261 cacttacacc gcttctcaac ccggtacgca ccagaaaatc attgatatgg ccatgaatgg
     7321 cgttggatgc cgggcaaccg cccgcattat gggcgttggc ctcaacacga ttttccgcca
     7381 tttaaaaaac tcaggccgca gtcggtaacc tcgcgcatac agccgggcag tgacgtcatc
     7441 gtctgcgcgg aaatggacga acagtgggga tacgtcgggg ctaaatcgcg ccagcgctgg
     7501 ctgttttacg cgtatgacag gctccggaag acggttgttg cgcacgtatt cggtgaacgc
     7561 actatggcga cactggggcg tcttatgagc ctgctgtcac cctttgacgt ggtgatatgg
     7621 atgacggatg gctggccgct gtatgaatcc cgcctgaagg gaaagctgca cgtaatcagc
     7681 aagcgatata cgcagcgaat tgagcggcat aacctgaatc tgaggcagca cctggcacgg
     7741 ctgggacgga agtcgctgtc gttctcaaaa tcggtggagc tgcatgacaa agtcatcggg
     7801 cattatctga acataaaaca ctatcaataa gttggagtca ttacccgttt gaagtatgta
     7861 tttcttgcag caaaaataat caaaaccgca agatatgtaa tcatgaagtt gtcggaaaac
     7921 tatccgtaca agggagtgta tgaaaaatgt ctggtataat aagaatatca tcaataaaat
     7981 tgagtgttgc tctgtggata acttgcagag tttattaagt atcattgcag caaagatgaa
     8041 atcaatgatt tatcaaaaat gattgaaagg tggttgtaaa taatgttaca atgtgtgaga
     8101 agcagtctaa attcttcgtg aaatagtgat ttttgaagct aataaaaaac acacgtggaa
     8161 tttaggaaaa acttatatct gctgctaaat ttaaccgttt gtcaacacgg tgcaaatcaa
     8221 acacactgat tgcgtctgac gggcccggac acctttttgc ttttaattac ggaactgatt
     8281 tcatgatgaa aaaatcgtta tgctgcgctc tgctgctgac agcctctttc tccacatttg
     8341 ctgccgcaaa aacagaacaa cagattgccg atatcgttaa tcgcaccatc accccgttga
     8401 tgcaggagca ggctattccg ggtatggccg ttgccgttat ctaccaggga aaaccctatt
     8461 atttcacctg gggtaaagcc gatatcgcca ataaccaccc agtcacgcag caaacgctgt
     8521 ttgagctagg atcggttagt aagacgttta acggcgtgtt gggcggcgat gctatcgccc
     8581 gcggcgaaat taagctcagc gatccggtca cgaaatactg gccagaactg acaggcaaac
     8641 agtggcaggg tatccgcctg ctgcacttag ccacctatac ggcaggcggc ctaccgctgc
     8701 agatccccga tgacgttagg gataaagccg cattactgca tttttatcaa aactggcagc
     8761 cgcaatggac tccgggcgct aagcgacttt acgctaactc cagcattggt ctgtttggcg
     8821 cgctggcggt gaaaccctca ggaatgagtt acgaagaggc aatgaccaga cgcgtcctgc
     8881 aaccattaaa actggcgcat acctggatta cggttccgca gaacgaacaa aaagattatg
     8941 cctggggcta tcgcgaaggg aagcccgtac acagttctcc gggacaactt gacgccgaag
     9001 cctatggcgt gaaatccagc gttattgata tggcccgctg ggttcaggcc aacatggatg
     9061 ccagccacgt tcaggagaaa acgctccagc agggcattgc gcttgcgcag tctcgctact
     9121 ggcgtattgg cgatatgtac cagggattag gctgggagat gctgaactgg ccgctgaaag
     9181 ctgattcgat catcaacggc agcgacagca aagtggcatt ggcagcgctt cccgccgttg
     9241 aggtaaaccc gcccgccccc gcagtgaaag cctcatgggt gcataaaacg ggctccactg
     9301 gtggatttgg cagctacgta gccttcgttc cagaaaaaaa ccttggcatc gtgatgctgg
     9361 caaacaaaag ctatcctaac cctgtccgtg tcgaggcggc ctggcgcatt cttgaaaagc
     9421 tgcaataact gacgatgagg cccaggatat tgggcctcct ttctttctct ttttttcctg
     9481 ttgtcatcta cacttaacaa aaatacagca aggaaaatcc catgcgcatt ttgcccgtcg
     9541 ttgctgcagt tacggctgca ttcctggttg tcgcgtgtag ctccccgaca ccgccgaaag
     9601 gcgttaccgt ggtaaataac tttgatgcca aacgctatct gggaacctgg tatgaaattg
     9661 cgcgcttcga ccatcgtttc gagcgcggat tggataaagt gaccgcaaca tacagcttgc
     9721 gcgacgacgg cggcatcaac gttattaaca agggctataa ccctgacagg gagatgtggc
     9781 agaaaacgga agggaaagcc tatttcaccg gcgacccaag cagagccgcg cttaaggttt
     9841 cttttttcgg ccccttctat ggcgggtata acgtaattgc actcgaccgg gaatatcgtc
     9901 acgcgctggt ttgtggtccg gatcgcgact acctgtggat cctttcacgg acccctacta
     9961 tttcagatga aatgaaacag caaatgttag ccatcgcgac ccgggaaggg tttgaagtga
    10021 ataaactgat ttgggtgaaa cagcctggcg cttagtgagt gctcagcttc agaccaataa
    10081 tgccagcaac gatcagccca aggctcagca aacgtgccgg gctggcagac tcacccagca
    10141 gcaaaatccc tgtaatggcc gccccaacag cgccaatacc ggtccagacc gcataagcgg
    10201 ttcctacagg caacgtgcgc attgcccaag agagcatggc gatactgacg atcatcgccg
    10261 caatagtgat aatgcttggc gtaagacgcg taaaaccgtg ggtgtatttc aggccaatcg
    10321 cccagacaac ttcgagcaaa cctgcaatta ataaaacgat ccaggacata tcaggctcca
    10381 gaacaatggg gccgtccccg gtgaaagaag cgtttgcagg tcgtcctgca aagctaatgt
    10441 gtgaaatggc atttttgccc ggaagaaaat gaatttcaac ctttttattc accgcctgct
    10501 aaaagcaaga attaagcata attagcggcg tagttcccgc atttggcact catcggagtt
    10561 ctctatgatg aagggctttc tgaaaccaga aagtcgagat aacattcctg cacagatcct
    10621 caaggaactc ccttcatgga gtatctatgt ttcagccgaa aatctgcata ctatacttcc
    10681 tacgtcctat ccgatacatg gatttttctt ttatccattt ttggacaata atggaaatat
    10741 tatccggctt ttcattattg atgatctgaa acaaagtcaa ggaactacag ggctaaaaga
    10801 aaagaatgtt gacgtcgtca ataatatcat cagaataaag gactctcgtg aaggacttct
    10861 tgactccaga aagatggagt gtatcgatgg tgaagtcgtc gtaacagtta acgaaaagct
    10921 caaagatttc agagacaggg agtttaatct tcttaacgca cagatatcaa tggtgcttta
    10981 tatctgttca cagatcaatg atataaaaga aaaaaatcaa tttaaacggt cagaaaagca
    11041 caaaaagcat gttcacactc accatgaact accagcacaa aacattcggg agtgggacgt
    11101 tggtattcga atggggcaag ccatacggca atatcgccaa gcagaaccca cagggaaaga
    11161 gcggacaaca ataggtagca aacgtcctca tatacgccgg ggacactggc atacatactg
    11221 gacaggaagt aagaaaccag aactagccca tgagcgtaaa cctagattaa tatggttacc
    11281 tccggtacca gttaatttag aagacgtaaa caaactaccg gtggtaataa cgcccattga
    11341 taaatgacct gagaagtatc ttttccggta ggatgtacac atatctaaat tatcaggcta
    11401 ctgtaatgtt gttcatgcat tacagtagag cccttggttg attgataaaa aaatctccag
    11461 gggctttctg ctgtataccg tccacaaaac gctttcggca tacagcctca agcgtccgcg
    11521 gctattctaa cgactttcgt atctgcaaca atccttttat cgcacggcta actcctctgg
    11581 ttagctctta tcacctgaaa ataaattttt aacctttccg tttgatttaa attccagaaa
    11641 tggagacttt gccatgtctt acaatcgaca gcctgtcgca gaagatccga tgcagatatg
    11701 gggcgctgtt ggtgtccttc ttatcctgct gctattcgtc atatggttat tcttgccgga
    11761 agtggtttac gccagctgcc tgattcttca taccttatgg ggactggttg actggggacc
    11821 atttcataac tatgcagcac cacgatacaa cctgcttgcc atgaccggta acaacgccgc
    11881 caacataagc tatagccagt gggttaacgt catggagcag accataggta ttttgtggat
    11941 gtacctctta cctgtgacac tctggtgttt gtgggaatgg tatcaacatc cgggacaaag
    12001 ccgtttcacc cgcagaccag tagatattac ccgactgcca cacatctttg cttcgttgtc
    12061 ccctgctatc gcccctgtac tggaagatgg tgatccggaa aaactctttc atggtggcaa
    12121 acgacctgaa cggcgggttg ctctcacccc ggaagcattt gtcgaacagc atactctcat
    12181 caccaatatg cagctcgatg ttgcagctgc aagacgatgt ttcatggccc agttgggtaa
    12241 acctttaacg tcctggaaag acatggcacc acatgaaaaa gcgctctttg ccatatttgg
    12301 ccttcagtat ttcctggatg atcgtaaggc agcattaaag ctcatggata cactgaacct
    12361 ctcatgcaga attaaaagca aacgggacag tgggaaattc tgtacccctg tttattcact
    12421 ggccaaatct gcattcaaaa gagtgattaa aagcgacgga gcacagcaat ggctgaaaca
    12481 acatcgctac gtccgcagtg ggctggtctg gctgtatgca catgacttgc ggcttacgcc
    12541 acccaactgg attttgtcaa cgacggatga aaagtgatcc acttatatct ccaccaacgg
    12601 cccaatattg atccaccgtt ttactcagga ttagcttctg ctataacccc ggcctttcgt
    12661 ttctgtctga gtcgatagct ttctcctttg atttgaacga catgtgagtg gtgtaagata
    12721 cggtccagca tcgctgaggt cagtgctgca tcaccggcga acgtttgatc ccactgcccg
    12781 aacggcagat tggatgtcag gatcattgcg ctcttttcgt aacgtttagc gatgacctgg
    12841 aagaacagct ttgcttcttc ctgactgaac ggcagatagc ctatttcatc aatgatgagc
    12901 aggcgggggc cattactcca cgctgaagcg tcgttttata acggccctga cgttgtgccg
    12961 tagataactg aagtaacaga tctgctgctg ttgtgaagcg aactttgata cctgcacgga
    13021 ctgcttcata gcccatcgct attgccagat gggttttccc cacacctgat ggccccagta
    13081 atacgatatt ttcattacgt tctatgaagc tgagtgagcg taacgactgg agttgcttct
    13141 gcggtgctcc ggtggcgaat gtgaagtcat actcttcgaa cgttttcacc gccgggaagg
    13201 ctgccattcg ggtatacatc gcctgtttac gttgatgacg tgccagtttt tcttcatgaa
    13261 gcagatgctc caggaagtcc atataactcc attcctggtc tactgcctgt tgtgacagcg
    13321 caggcgctgc gcttataagg ctttccagtt gcaactgccc ggcgagcgcc atcagtcgtt
    13381 gatgttgcag ttccatcatc acgccactcc tctgcagaat gagtcgtaga tggagagtgg
    13441 atgatgcagg gggtgtttgt cgaagttcac cagattttca ccaggatgca cgtcatactc
    13501 ttttttctcc ggaggcagtg ccagcatgga ctgctgctct tcgagccagc gatcgcaggg
    13561 acgggcctgg attgtttcat gctttcgttg gttagcgaca tcgtgcagcc agcgcagacc
    13621 gtggcggttg gctgtttcaa catcgacagt gatccccatc gggcgcaggc gagtcattag
    13681 tggaatgtaa aaactgttac gggtgtactg caccatccgt tccaccttac ctttagtctg
    13741 tgccctgaag gggcgacaca gtcggggaga gaagcccatc tccttgccga actgccacag
    13801 cgaaggatgg aaccggtgct gaccggtctg atatgcgtca cgttgcagaa ccacagtttt
    13861 catattgtca tacaacactt cgcgcggcac accaccaaag aagcggaacg cattacgatg
    13921 gcaggtctcc agcgtgtcat aacgcatatt gtcagtgaat tcgatgtaca acattcggct
    13981 gtatccgaga acagcaacga acacgtgaag cggtgagcgg ccattacgca tagtgcccca
    14041 gtcaacctgc atctgtcgtc cgggttcagt ttcgaaccga acggcaggct cctgctcctg
    14101 aggaaccgag agagaacgaa tgaatcccct gagaatggtc attccgccac gatatccctg
    14161 gtctctgatc tcgcgagcga ttaccgttgc cgggattttg taaggatgag catcggcgat
    14221 gcgttgacga atataatccc ggtattcatc caggagtgaa gcaacagcag gtcgcggcgt
    14281 atattttggc ggctcagatt ttgcctgcaa ataacgttta acggtattgc gggagatccc
    14341 cagttctctg gcaatcgccc ggctactcat tccctgcttg tgcaggattt taatttccat
    14401 aactgtctca aaagtgacca taaactctcc tgaatcagga gagcagatta ccccctggat
    14461 ctgatttcag gcgttgggtg tggatcacta ttgcaccgtt cgtgacagaa tgtagtgaaa
    14521 aacaggatca gtattatctt tcgcatagtg tgcctgctgt gcaatgtact ccatatctgc
    14581 agcagcagtt tcaagcgatg tacagttgtg aaaacaggtc acaccgtaaa agttaaccca
    14641 ttcgcagccg tccttcatga catcaaccag cgccacgaat gactcatttc gaaggcgtgt
    14701 cgcataatca acaaggcgac tgaaacggct ccggtgcggt tgttcagcct gcgaagaaga
    14761 agataaattc agttcctcat cggtcatgtc atcccggacc gagacgtagg acaccaggtc
    14821 ttcgaacgaa gacttgccgt cccttctctt tttcggaatg actgcattca ccggagaatc
    14881 ctcaaccttc cattaactgt ttacgcaatg tatttgtaag ttcggttatg gcaacaagca
    14941 cttctgcgta ttccttgtca ccggttcttt ttccctgaac aaacagatgc ttctgcatcc
    15001 ttcccagtct cattaactcc ttcagaaaag catcatctgt acgggagtta attcgcttat
    15061 tcagtgctgc atttcggatg taagcagata cagtaagtcc ggaatcttca gcttttttcc
    15121 tgatggtttc atcctcaaca ggagagaatc tgagtgtcct gacaactgtc ttttgccgta
    15181 cctcactttt ctttcttacc gcactatcac tcacttcagg ctccttacgg ggtgtcgggg
    15241 cgaagccctg accagatggt aattgtaata gcgtcgcgtg tgacggtatt acaattacac
    15301 atcctgtccc gtttttcagg ccattatagc ctgttatttt tgtgcatcat agtcttatgc
    15361 agacggcaga ggcagggcgc agccctgcca ggagtcattt tttgatgata aaatcagact
    15421 tcaacatgaa acggagagaa agtgccaatg gcttctaaaa aattttactc agatgatgac
    15481 atccagctgg caaaagctgc tttatcggaa ttgccggacc tcaccgctca acggaaaaca
    15541 ttgcgtgatt ttcttgatgc cattcgtgat gacatcatta tcctggtaag gacaaagggt
    15601 tatacactgg cagatgttcg tgacacgctc aaaaatgcag ggtatgaagt aggagagaag
    15661 gcacttcgtg acattattcg ggaagcagaa tcgaaaaaaa catcccgccg ttcttcctct
    15721 aaaacagcac ctaaaaagac agattcaggc aggaaagatg gcatcgatat gaacaacaat
    15781 tgatgtgaca atgtcacatc gtgttctgag attatgatga ttacagaaaa aaaaagcccc
    15841 ggcataaata ccagggcttt tctgtttaat cagactcgtg gcggcaatgc acctggataa
    15901 tgccgtgcaa taatatcatt cagtttttca acaaggtcag aacgcttaaa gacaatgtgt
    15961 acggtccctt tctggtagcc acgcaccgta aaatattccc cttctaacag cttaccgaca
    16021 ttgtcgccgt tcccgagaaa ttcaccatac tgcgccccga tgctgttcct gaagtcagga
    16081 acgttgcgcc cctccagcag ataaaacgga cgtaccaggt catccagtgc ctcccgtccg
    16141 ctgcagtcca gcgtcacacg cccattactc cagcggtaca gcaggttttc aataatgatt
    16201 ttcttaccca gacggcaggg attattggtt ctgtaatccc atgacaattt ccggtagaca
    16261 tcaatcagtc cctgttcaaa cgtctgcatc ttgctggcat taagatggcg gaatgttgcc
    16321 agtacattgt ccagggtgat ttcaggacag gtgtcgctca tcagctggct gttccactca
    16381 tcacgctggc atgaactcat gaaggtgtac atgcccgtat ctgtcatcag gcggtcccag
    16441 attttccggt cggcaagacg ggtgatattc cttttcgctt cttccggttt atccatgcga
    16501 cgaacggaat cagtcacgca gtcttcaaac ccgtaaagaa aaatatcacc tgacgcatcg
    16561 agcagaatct tgcgcgctgt cgccaggcat tccatcgcct gcatgaacag tgcaatacct
    16621 tcgttacgct gcgcgatgat gcggtcgata gccacagacg gaataacatc tgtcgtgccg
    16681 gcagtattca ggtcagcagt gggtaaagtc tgattcatca cattgtctcc tcatcgtcac
    16741 gactgccggg tcagccaggt catttcccgg aggagcgaag ctccttctgc cgtccgggtc
    16801 ttcggggatt tccccgcagt ggacctttcc gacgggggac gctcaccacg tcacggggca
    16861 gttgtccggg ggcagacgca aaagtttttg acgcctgcgg caaaaagttt tgtggctggt
    16921 acatctctcc cctggacgac tgaaacggga tgtggtcgtg tatgtacccc cggaaagtcc
    16981 gtctgcggag aacaggccgc agtgcggcgg cagacaggca gagacagctg cgccatcagg
    17041 cgcagtggcc ttacacaccg taaggtgtgc agggagcgcc gcatccggcg cgactgaaga
    17101 aaaacgacgg cacaacaatg gcatgtggtg gtcactggca caccactccc gcacaggtga
    17161 aaacagagaa aaccgcacga catttacaac caaaaaaagt gaaatttctt cacttttttt
    17221 cacttattta tcgcgctgat ttggcaattg tgatgataaa ataaagtgag gttttttcac
    17281 tttttcaaag gtgttttatg actggctggg aactgcgaat ctggcgaaaa agcatgctct
    17341 ggtcacgcga aaaagcggcc agagaatttg gcgtgacgca gagaacatgg cacgcctggg
    17401 aaaatgcgga acaggtggac gtcaccgtct ggaggaccac ccaggcactt tcagtccgtg
    17461 acctgctgcc tcacatgcag gggatgcgca aggcagatat catcaggcgt ctggaaaatg
    17521 aactggggga aacggcagag gatgtgtgag cgtgattcac agcctggcag aatgccaggc
    17581 tactgctcat caggaaacag ttttttcagt tcttcaccgg aaagtccggc tgcctcctga
    17641 atccgttccg gcgtccagcc catatcccgc agccggcagg ctgcttcccg cgccacttca
    17701 agcgcacctt tcttaaaacc ttctttaaaa ccttcgtcga aaccttcgtc gaaacctttc
    17761 tgtataagac gttctgcaat cgtcatactg ttttctctgc tcctgctggc aaaaggcccg
    17821 gtattttgcc gggctgtgag gttctcatca gtgaatgatt ttcttcagtt cgtcatcgga
    17881 aagtccggta gcctgcttaa tctgctccgg cgtcatcccc attttctgaa gctggcacgc
    17941 aatagccagg gctttttcaa gcgcaccttc catcctgccc tcctggcgac ctttttgctc
    18001 aagacgttct gcgatagtca tcagtttatc ctcatgctgc ggcagacgct cagccagcgc
    18061 ccgcataaat tccggtgata cagagtcccc tgcgttaacg atgtaatgaa tcagaacacg
    18121 cacctgctcg tctgaaattt ccaccatgac ctgcgggagt ttgtccagca gctccatcat
    18181 gtcacgatgg cggatatgct tcatcagcag cgtcagtgcg gccatccggc gatggttcat
    18241 gatttcattg tcatcaacga cagtgatatc aaccagcgga aacggctttg tgtatatttt
    18301 agccgcaagc gccggattct caaaacagtc cagccagttc atgctgtacg gatacgggct
    18361 gcgctcacca tgatagaaca gcaccggaat caccagtggc aacgttttgt gctgctccag
    18421 atgtctctgc atcgccgcca cactgtaacg taacatgcgg aaaggcatgt acagattttc
    18481 ggtgctctgg tgctcgatga gcgtataaac atagccgtct ttacccccgg tggttttcac
    18541 gctccagagg atatcgctgg cgtactgatg caggtccggc tctacaaagg tggcgggttc
    18601 cagcttcagc gtggacaggt cgcacaactg ccggtactcc gcaggaagat gcagttccag
    18661 aaaatctctg gcgacgtcgg gattcgccag gaacgaccgg aacacggcat catgcggcgt
    18721 gggcgtcgtg gtgtttttct tcttactcac ggttcctcca tcaaatcagc agcatcgcag
    18781 caatcatcgc ccaaatcccc acaaccgaga ggacagcaat tgcgttcaaa gccatgacaa
    18841 caatagccgc gttctgagtc acggcgtatt tcttcagcaa tctcttctgc ggaaaggtaa
    18901 tcaaactcct cacgggccag ttccaggacc agtagatgtt gttctgtcgg caatgtggcc
    18961 acaaaattat caatagcagc actcaaacgt cgctgatata gctcataaac aagaccacaa
    19021 cggggcatta gttcttcgga taatagttcc agttttgagc gaattctgtc agcgttgaaa
    19081 gtgacttcat caaaagacat atgaaaagct ttgtcagtat caaaacaaga cttcattgtt
    19141 atctccagcc ctcccgggcc ctgaatgaaa gagaatctgt ttcccttttc tgttttttgt
    19201 ggagacacca tgcaacacag acgtcgtgat gtttttcatc ttgctcacgg ttcctcctgg
    19261 taaagtacct gaacacatcc tgccacctgc acaggcagac ggcaggggtt aatcagtgac
    19321 agacccgttc aatttcaagc gcgcggagca ggtggcccca ttcgctgact ttcatggcgg
    19381 ggatacgtac ccgcttctgc tcactgcagc gtctggcgat atgaccgctc atcgccagga
    19441 cgtccgggtt aatctcatcc tgtgccagct cctgacgtct gaagcgggta tggcggtgca
    19501 ggggtttatt ctcccgcagg cactcttcac gcagacgctt tacatactcg gcggttgcga
    19561 agataattga tggtttcatg gcataatctc catagatagt gattgagatg ccgggcttcc
    19621 tggcggggaa gcgccggcgg agagaggcag ggtttatcgc cctgcctttt tttcatttcg
    19681 gacagcggcg cagtgccagc gcgagcgctt tcatcttcca gccttccggc gtgcgataca
    19741 tcaccttcca gtagccgtcg atgaacacat aatggaagcg cacctcttca gtgctttcag
    19801 tggcaatagc ctccatgaaa gaacggtact cacgcgcctc actgtccatc cggaaaccac
    19861 tgtcacgtcc gtaataagcc gtcacaccgt ccaccgggtt ctgaagcgta tgcccggcgg
    19921 gtttgtcgca acggggaccg aggcaacgga tatcaccgtg ttcaaccagg gcttcggcct
    19981 gctgaccagt ggcatagtgg gtatgcagga tgcgaccgtt ccaggtcggc tcaccgtgca
    20041 ggtggcagta aacggtacgg aacaccccgt cgcggcaaaa aacggaaatc gtgctgctga
    20101 ctgtcatgaa aacgtctcct tctgctgaat caggtcgccg ggccgaccgg ttgctccccg
    20161 gaggggcgaa agccccttct gccgtccact tcttcggggt ttctccccgc agtggacctt
    20221 tccgatgggg cgtccgtcac cacgtcacgg ggcagctgtc cgggggcgga cgcaaaattt
    20281 tttgccgggt ttatggctaa aaattttgtg gacggtatat cttcccctgg actgctgaaa
    20341 cgggatgtgg ttactccagc ccccggaaag tccacagcgg gaaacaggcc gcaggggtgg
    20401 cggcggaagg gttggctgcg ccatcaggcg cagttgcctt acacaccgtc aggtgtgcag
    20461 ggagcgccgt ttccggcgcg acaggggcgg cgcgaccgga acggtcgctg caagcctggt
    20521 ttttcagaca tcggaccgta gcggcagccc gaaaccgcgc cagcgggttc ggcggagact
    20581 ggcgggtgcg ccagcagctg cctgtcggag tcgggcctga cgaccggatg ccgccaggca
    20641 gccgggagcc gaaggtgtcc ccgcctccgg aaatcagaac aacagaaacg acataacaga
    20701 aaaatgcctc acaccatgac gggcaggaag ggcagcgccg caggcgcggc cctcctgcat
    20761 ttcaggcagg cgtaagcctg ccagggtttt ccggcggcct ggcaggccat acccccgccg
    20821 gagcggggga gtaaatcacc gacggaacac atgaccgtca ataaaggtga aggagtccag
    20881 gaataaatcc cgcgcatacg cctcatagtc aaaatagagc gccaccgtct ccggcacgtc
    20941 agccagcagg ccggtatcac tggcgaactc aaccgcaaaa gcctcctcac tgtcagcctc
    21001 gccccaccag gcatcgcgga aggtgtcaaa atccgtctca ccggtatcat ccacccagag
    21061 acgataagcc tcttcgcagc cttcatcccg tgcccggcgg aagccttcaa cccaggccca
    21121 gttgatatga cattcagagg ccatattccc cgggaatccc tcataatcct gaaacatcag
    21181 ttcaggatcg gcttcatcct ggtgaagagc acggcaggcg gcgaaaaagt cgcgctcatc
    21241 atcaaacgtg gtcaggtcaa accagcgtcc ggcgatgctt ccacagttgt atttgtgcca
    21301 ggttccaacg tatacagcag gtgcaacaac agacattccc gaatcctcca tagtcacatg
    21361 ttctgcgaca ccgggcggtg ccgtgcctcc ataaaagccg ggcgataagg cggggatgca
    21421 ggggcgcaag ggaagccgca gcctgacgca cacggctgac gggagttgca gggtgaggcc
    21481 gcgaaacctg agcggacgaa cgaccggaaa atcacggcag acgggaagga gggaccgggt
    21541 gaccgcagcg gcgaagcgta cccttgcatc cctgccagcc cggctaagat ggaggcacgg
    21601 cacagcccgc acacgacgct gaggccacag agctgaaaac ccacaaggcc atgccccgca
    21661 tggccgggta aaagcggagc cgccggcgac ttccttattc cggcgagtgc agaggacacg
    21721 ccgcatgacc tccagaccac ccctgatatg aaacgatcat gatcggcgtg tccctgcgta
    21781 aaatatacat gcctggttca ccggagaata tctgtgatat ccacaagttt tctgtcgcgc
    21841 agccagtcct gcgcttcacg caccacacaa ctgtccggtt tcaccgcttt cagcgatgat
    21901 gccagtcgct tgatcaacat caccagttcc cgtgtctgta tgtccggcat tgtctccggc
    21961 ggagcagggg gactctcatt tccgacgctc atcccatgcg cttccagtgt ggcacggaca
    22021 aaccaggcgg catcgaccag ttgctgtcca atccaggcca gatcggcatt tctgtcacgg
    22081 gctgccattc gctcgcccga cagcgccttg ctgatatggc tgcgcaccag attatccagg
    22141 agtgcctgcg cttcttccgg tgaaaagcca cctggtatct ctgtgcgcaa cagccctttc
    22201 ctgtacagaa gctgcagcag atcaacctgc gaccgcacag caactatcag tacataacgg
    22261 acaacattcg cactggcagt ggtttctgta tcattcagca gttcttccgg atcgttcccc
    22321 ccggtgttgc agagcaacgg caacagaggt cgcatccacg cgggaacctg gtatttttcg
    22381 tctgatttca tcatattacg ttctccagct tgttcgggat catccactgc tcaagtgcac
    22441 gtacctgtac cggtgcacca cgaccggcct caccggcttc aaaaatcagc cgccagagtg
    22501 gttcctcctg ccagaaaaac cggtcaaatg atgacagtga tggaaaacgc ccgcaccacc
    22561 cccagaaaat cgtttccaga tcatgctcct caacaacacc agaccagcgg gacaaccagc
    22621 ttccgaccgt ggcgggagta tgaaacgcaa ggtcaatctg cgcctgagca aaacatgtct
    22681 ggtattccag ttcccgtcgt tctgcctcac gttcccgctg gcggctgtat ttctgctctg
    22741 tcatgtcccg tgaccatccc tccggtaaca gggccgcaag acgggctttt tctgccatca
    22801 gcgccaggaa tgcggcacct tccttccctg acggcgcatc gctggtcagc gaataatgtt
    22861 tacattccag gctgatttgt gctggtttac tgtacgctcc gctgtcaaac acattcaggc
    22921 agagcgtcca tgccaacagt gcaagagatt tgtccggttg ctgcatcagt gctgcctgga
    22981 ctgccagcgt gcgttcggaa gacattttcg tcagcaacgg cagactgatt gcctccactg
    23041 acgctttctc ctgcacctgt tccgtgcggt cagcgtcatc agtcgcgtca tcttcactgc
    23101 gcaactgcac accacgctgg acacacacgt tgccataacg ccaggacacc accactccac
    23161 ctccggcacg catctccggc gtccacgctc tgaccttcgc catgcagcgc atcagcttca
    23221 tttctgcttc cagcaggtca gattcctcac actggttttc cagcgcgtcg taacgtgcca
    23281 tcagttcgtt cagacgttct tcttccgcct cggtcagcac cgcttccggc tccggcagac
    23341 agcggtatgt tccggcatcc tcacggcact caccgacagg ctccatgcgt ccggcgcacc
    23401 attcccagcc ttcggcttcc cgaaggaact ctgcgacagc ctggagtttt tccagcaggg
    23461 cggcatcgag cgccacgcag tccacatagc caccctcgtc gtcgctgaac aaatcggtgc
    23521 gcagttcgtc tggcgagaag gcatcagccc ccacgaagcg gaatttactg ttccccgcca
    23581 ccgccacttc actttccgta atcagattgc ggataacccg cacatccggt ttggggatgt
    23641 aacggacttc cggatcatta cccagacggt agggtagggt acgtgtggtc tttcaagata
    23701 aatggcgaat atgtcctgct tatcttgagt tagatcaccg ttaccccccc tccgaaccgt
    23761 acgtgcacct ttcaatgcat acggctctcc attgctagct tattggggat aaactcattt
    23821 agcagaatcc ccacttgaga caggtggttg caggagtatt cttccctttt cctgtctcag
    23881 atcgggtagt tttccgctat gtaacttgtc gtggcaactt gcgcacaaaa tcatcgtttt
    23941 ccggcggcgt gcgatcatca ttagttgcca caggctgggt ttatatccgg ccttacgacc
    24001 tttcttcagg tcttttagct ttctgacatg atgtacttcg cagcgcccag tcttcgcaca
    24061 atactcgcag atccttgccc ctaatcgacg catgatctct gttgtgcggg ttgtgatatg
    24121 tgcggttctc ggttccgtat cgacaatcgt tgttcggttg cgattgacat gtttgagttt
    24181 gaaaacctca atctttcggg atccattttt ggcctgaacg gtaatagcca gatctccatt
    24241 attttgccgt agcgatttgg cgactttatt cactgaacta cgtcgtttat tcgctagggt
    24301 cttaaaaagg cttatttgcc atatgaaata taattttgat aatttatatt tcatgtccag
    24361 cgccagactg tagtagttcg ccaatccgcg catttccgcg ttgaaagtca gaacaatttc
    24421 agcttcactg agattttgta gacttgaacg atgtacagcc ttcacattct cataacagcc
    24481 atatttcttt tggtgacaaa atttagcggc tatattgtca ggaacgaaga gctgcacaat
    24541 tcctgtggtg gatctccgga gagcgtgccg cccttgcatt ttctgcttca gcaatttctt
    24601 tgcatctgcc tgtctgattt catagcctaa aaaattaact ccttctgaga tatggcggat
    24661 cctggtcttt gcttcattaa cttccaatcc cagtgaagta gtaataaagt ttctgacctg
    24721 tcttgatata tgttcagcat ctttcttcga gccgatgaca ccaattacga agtcatcagc
    24781 atatcgaaca tagtacatac gcctgaagtt tggatcgttc atgacctgag atggtataga
    24841 acgtttttct tcaagcagtc gttcaatttc tttctttatg gcttcttttt ctgattcaga
    24901 atcagttgcc ataccgtcta ctttctttcg tagtttatga atcttatggg ccagcctgtt
    24961 catatctgga ttcgctcttc gttttgtacc gcttgtatat gcaggaatta agttctgttc
    25021 tacaaaacgg tccagtttgt cgaggtatat atttgccagt aagggagaaa ttatcccacc
    25081 ttgtggcgtg ccagaatatg agcgatggta tttccaattg tccacatatc ctgccttcag
    25141 ccactgttcg attaatttca ggaaattctt atccttaatt ttctctgcca gtgtattcag
    25201 caatagtttg tgggggatat tgtcaaagaa acctttgata tcaacatcca cgatccattt
    25261 aactccgttc cagactggac gaatagatct gagcgcagtt tcacacgaac gttttggtct
    25321 gaatccatga gagtgttcag agaatactgg ttcataaacc ctttccagaa taattcttgc
    25381 tacttcttgc gccagtttat cgtctccacc tggaatcccc agcggtctgg tttttccgtc
    25441 cttttttggg atctgaactc tgcgtacagg tttcgctacg tattctctac tccgcaatgt
    25501 ttttgccagc ttctctgctc tttcgataga gaagccatca atggtatctg ttgatacacc
    25561 ttgagtcagt gcacctgcat tggcccgtat attcacgtag gcttgcagcc acagtccggg
    25621 ctcacacgca attttgtata gattacgtac tggataccct ttttttgaag catcctcaat
    25681 tccatctaat cttttctcaa gttcatcagg cagcattggc taaccctcct cttagagatt
    25741 gatgtatcta acaactgtct cccttccccg cagcactgtg aggctttcat ctcccttccg
    25801 gttgatttat acctttgctg cttccgtata atgcggactg ccgtagccca ttacaggccg
    25861 accttgagta ctatggagac tccgctacca tgctgggtat aaatccagtt taggtagtcc
    25921 cgtagtttca cggtgtggag atgcgatgta cttaggatgt ctttcgatcg tttaactatt
    25981 tcatcaatag ctggcccgtt agagtggtca caatcaacgt agggcggatt tcttgtgcta
    26041 ttacgggaat aacgcttcaa tcgttctgcg ttattggttt cctgtttccc acatagatct
    26101 cgacttcaac aaacccagtt tgccgatcgt tgccaggccg gttttccttc gcctgccact
    26161 gattatgctg agcaggaact ggatctgaac agctattgca tcagcagacc tgcagccacc
    26221 ttctttctgc gcgccagcgg tgaatcgatg aaccaggctg gcgtgcagaa tggtgatctg
    26281 ctggtagtgg acagggccga aaaaccacaa cacggggaca tcgttatcgc tgagatcgac
    26341 ggtgagttca ccgtcaaacg actgctgttg cgcccacgcc cggcactgga gccggtttca
    26401 gacagcccgg agttccgcac actgtatccg gaaaacatct gtatttttgg tgttgtcact
    26461 cacgtgatac acaggacgcg ggagttacgc tgatgtttgc actggctgat atcaacagtt
    26521 tctacgcctc atgtgaaaaa gttttccgcc cggaccttcg caacgaaccg gtcatcgtac
    26581 tcagcaataa cgatggctgt gtgatcgcgc gcagcccgga ggcaaaagcc cttggcatca
    26641 aaatggggca gccctggttt caggtgagac agatgcgcct ggagaagaaa atacatgtat
    26701 tttccagcaa ttatgcgctg taccacagca tgagccaacg ggtcatggct gttctggagt
    26761 cgctttctcc cgcagttgag ccctactcaa ttgatgaaat gtttattgat ttgcggggga
    26821 taaatcattg catctctccg gatttttttg gtcatcagct cagggaacag gtaaagagct
    26881 ggacaggact caccatgggg gtgggcattg cgcctacaaa aacgctggct aaaagtgcac
    26941 agtgggcaac aaagcaatgg ccacagtttt ccggagtggt cgcgctgacg gcagaaaacc
    27001 gtaatcggac cttgaagcta ctggggctgc agccagttgg tgaggtctgg ggagtaggac
    27061 gcagactgac ggaaaagctg aatgcgctgg gtattaacac agcactgcag ctggcgcagg
    27121 ctaacacggc attcatccgg aaaaacttca gcgtcattct tgagcgtacg gtacgcgaac
    27181 tcaacggcga gtcctgcata tccctggaag aagcaccacc ggcaaaacag cagattgtct
    27241 gtagtcgcag ttttggtgaa cgaatcacag acaaagatgc catgcaccag gctgttgttc
    27301 agtatgcaga gcgggccgca gagaaactac gtggggagcg tcagtattgc cggcaggtga
    27361 cgacatttgt acggacatcc ccctttgcag taaaagaacc ctgttacagc aatgccgctg
    27421 tggaaaagct tccattgccc acacaggaca gccgggacat tattgccgcc gcatgcagag
    27481 ccttaaacca tgtctggcgt gaagggtacc gctatatgaa ggcaggagtc atgctggctg
    27541 atttcacacc atcgggtata gcacagccgg gattatttga tgaaatccag ccccgtaaaa
    27601 acagtgaaaa gttaatgaaa acactcgatg aactgaacca gtcgggaaaa gggacagtgt
    27661 ggtttgcggg gcgaggaacc gcccctgagt ggcaaatgaa acgggaaatg ctttctcctg
    27721 cgtataccac cagatggaca gatttgccag tagcccagtt atgaatatgt aatccaccca
    27781 taatattgtt atcttgttat cttgttatct tgttatcttg ttatcttaat taatctataa
    27841 atcaaatact taacagcttg ttaagttgtt aacataacaa aaataattgc atggttcgcg
    27901 ttcagatggc aatattaagt tgttaactta acagcttaat atgaggctat aatgataata
    27961 gtattaggta gtcaaaaggg tggggtaggt aaaagtacac tggcggtatc tatagctgcg
    28021 tatctgatgt cactaggcaa tagagtgatt attgtcgacg cagatgacca gaaatcagta
    28081 ttaacctggt acaacaatcg ccctgaagat ctccctcata ttccggttac aggcgcgaca
    28141 ggtaacatca aagccatgtt aaaggaacac gaaaaatcct atgattttgt tattgcagac
    28201 tgtgctggcc gtgatagcgc agaaatgcgt agtggattga tggccgcaga tgtattcatt
    28261 tctcctttgc gcccatctca gatggacctg gatgttgtgc ctcatacatg ctccgttttt
    28321 acagcagcaa aagattttaa tgaggatgtt cggggatatc tcgttttaaa catgacgccc
    28381 acaaatatgt ttgttaatga agccaatgag gcagctgaag tacttaagga ttaccctgaa
    28441 atgcatctgg caaactcccg ggtatgtgat cgtaaagcac atcgagatgc ttgggccgaa
    28501 tcaatgacaa tttttgaaac gcaaaatgat aaagcccagc aagaaatcga agcgttagtg
    28561 aaagaggtta ttctgtgaga aatagagcaa acacttcacc tcgtgacgag gcagcattta
    28621 ttaacggtgg cacggctggc cttgataata ccaaaaagtc atcagataaa tcatcggttg
    28681 taagcaaagc aaaaccagtg agtatttctt tttttgaaga aaacctaaaa gacattgatg
    28741 cccttataac ggctgagatg gtttcaggta aaggcagagt gaatcgttct gatgttgtca
    28801 gggcggcggt agaagcactt aaaacactat caaaaacaga ggtatcacga ttgatagcag
    28861 aagtaaaaca aagataacac cttactatct tgttatcttg ttatcttgtt atcttgttat
    28921 cttgttatct tgttatcttg ttatcttcaa tgtattttag gatgacctat gttgaataga
    28981 acctaaaaca aaacaaatat taataggggt ccgcttggaa aagcggaaat tttcccacgc
    29041 taagagaatt gagttgaacg agtggttaca tccaggccag ctaactcact gaaccccgta
    29101 caggatcaga cattcggtat ctccttcatc ctctgaggaa aacaaatgaa ttaactgctt
    29161 acgtatatgg atacatatac agtattaatt tattaaggag aaaatggcat gtcaagattt
    29221 aatgatagtg attatcatta acatgaagtg atgttacacc gttcagaaag cctgctgacg
    29281 ctgtggcagc atcacagtct gagtattctc tggtgcaata caaaaaccgg actttcccgt
    29341 aacaacagac aatgttacgg gaaaagttac agaactgagc cacaaaatat ctcagtacct
    29401 gagatgcata aaaacaccgt acatatgttt ctcaaaaggg ggatgatcgt tatccagcca
    29461 tttcggtgga tcggtatgca gaacaccaat ctgcttcatg ccggtatgct gcctggattt
    29521 tctcgcgcag taatcactgt cttcatatcc catcgtttcg atgaccactc tggccgtctt
    29581 tccgtcagga gccattgctg tgacaatgaa atccggcagt acatatttct tttcaccatt
    29641 aacataaact tctgtatcaa acaggggcct ttccagactt aattccggcg tacctggctt
    29701 tcttttaagc cagctggcca cattcagaag agcagtgagc gtgtttcgtt ccagtttgct
    29761 gtccacagga accggacatg tcagttgata aagagcatga gcataccctt cactgcagat
    29821 gattctgcca tcggcactcc ggcaaaaagc aagaataacc cagtaagggg gacgtattcc
    29881 gccctgcgct tcaccattaa tactgatccc ccgcacaggt ctgaagacct gaatattacc
    29941 gttcgcccag tgaatttcca cagcatcacg acagatgtgc tgcgccataa aaatctgaaa
    30001 gaacatatgt tttcttctgg caggccagtg tcgttctgaa ttctccagcg tttccattaa
    30061 ccgctcctga gacctttcag acattcctgg ccggaaatgg ataatttcag ataaggatct
    30121 tccccgaata tactcctgct gtagtgtaac ctgccgtatg gcatcaagac actcacgata
    30181 attagtccgg atacggggat tagccaggga atccagttta ttcagccctg catcttcaat
    30241 aagcgacagg agtaaacggc caaggcgcgg acgtttcttg cgaacggagg agcgctcacc
    30301 attatggtaa gcagagcggg tctgcagtct gataacagaa ttactgtcat caggtggtaa
    30361 aaagtttctg taatttatac gggtgctaac gggatgccgg cttgctccga aggatgtttc
    30421 ctcttcattt cctgataact gacgatacat ggggcattca ggtgcatgct catgattaaa
    30481 actggacaga taaagagtac ccgtattgtt tttaagagca gcaaaattca tggccggcga
    30541 atctcccgga atacagtcac actgtaacca tgcatcatac tcacgcattt cccggagaag
    30601 atcattggcc aggttatgtt gtgccatggt tgctggcttt ttcagtccac agaccgtctt
    30661 tactgcagtc tcttcctcac tgctaagctc ccgaatcact ttgccccggg gattcttctt
    30721 tacaagtatc attggcataa tgaaagcact ccttatgtac atgcttaaac agtaagtaaa
    30781 atatacaaag aacacaccat gaaacaaagg cagagatgaa ctgtgcgccc cgatatcttc
    30841 ttctgacatc ctttcaaatg aatttttttt atttatatca tgacaacatt aacgttagag
    30901 aatatatcaa ccatgtttcg gtcagggttc agtcgaatat caattcgact gtcacgccat
    30961 aactgttacc gcctcgagta taaatattca gagaacggac ttataaacca tgaaaaatca
    31021 cctgacggaa aatttactaa tttatggatt gtgatattat taaagagtaa aaccagccag
    31081 ccgaggtatt tatggaaaaa aatcaggaag aaaggaaaat ccccgtcatt gtagtgaaaa
    31141 aacgtcgtac cttttcgtta ccttccttat ccgaaaaaac agatattatc gaatctgcat
    31201 ttactgaaca ggcagcagaa tcagcccccg tcggaataaa ttcatctgcc gtcgaaacac
    31261 atatccccga agcaccagcc aggaagaaga aaaagaaaaa acgccgtttc ccacgtccct
    31321 cccactggac cagagagtat actcacgagt gcgtggaaaa aataaagatc ctgtttcctc
    31381 atcttcgtgc tgaaggtggt ggatttattc ccctgaaaat tggcataaac aatgatattt
    31441 cagcatttct ggcagaacac ccggagacag aactgaccat ggacgaatgg ctctgtgcag
    31501 tgtcctgcat cacctcacgc cgtgtatatc tgcagcggac agctgtcgcc ggcgtcccac
    31561 gttatggtct ggatggtcac cccaaagggc aggtctcaga atctgaagca cagagtgccg
    31621 gtcgcagact ggtgacatta gaacaaaagt tgctcaggat gcaggcacag caggagaata
    31681 tttctgggca ataaacactc ctgataacag ctggacatta cgtatcagaa aaatgggaag
    31741 agaattatta tgagtaaatc aggtgcagaa aaaattcaat tcatcctgaa taatcatgaa
    31801 caggcataca gacgcctgaa gcctgtatat acttttttag aactggcatc ttggatttcg
    31861 gttgttctgc tgattatata cctatcaggc aagaatcacg tgcttacagc agcttttctc
    31921 tgctttgcat ggacagcatt ctgggttctt ttccttttac attatttccc aaaagttttc
    31981 tctattctcg atcgtcagag tctgctcaac ctcatggagg ccaccaaaga ctcaccagat
    32041 gtaaagcagg agctgcttaa ccgccttttt tccggaaaaa gaatgaccgg gcgggatgaa
    32101 atggatatct gccgtcttct gagaaaaaat gaagaagaaa aaatccgtca gagtgaactg
    32161 aatatcatca ggaattttat tgatgaacag cagttaacga atagtgatat tccgaagaaa
    32221 agtacggtcc caaatgaaga taaaaaaggc ataagatgat atgaaattaa taaccaggca
    32281 agcagaggat ggcgtggttt catcctaaga ttgatagggg ttaacctgta agataaaagg
    32341 accgtgttta cacgacgtct ctgaagggct tcgtttggga aacggacaat atctaactga
    32401 cgaggaaatt aaataagggt ttaaaaatta acgcaccata tattatacac agtatataac
    32461 gattcagata tcgtcaccag gatatgccgc gtcagcggca tggaaggcgg cactctgttg
    32521 ttgcatatga cacaggagta aaaccgccga agcccggcgt aagccggtac ggactgatag
    32581 atttcacctt acccatcccc agccctgcca gaccataccc gttttcagcc atgagagagc
    32641 ttctgtgcgc ggtcggagtg gtcccgacga gggtttaccc gaagtcgggg cgtatctccg
    32701 cgttagcggg ccgtcagggc cgcttacgag cgtgtacgga ggacttccag ccagaagact
    32761 ggcagcgatg ataatgtagt tacaacattc ataattaaaa gcgatgttgt tcccgccctt
    32821 tgggcggggg cggcctcgct tttcagttat gaggggtagg cacggtgctg cgtttgtgcg
    32881 gtgtttttat tcctgatgtc tttttgttgt ggtttcagaa cggtgaggtt cggggcccgc
    32941 gcgtcagcgt gggaggtgct tttagattct gagcggcgcg gccttggccg ctgcaagcga
    33001 aggcctctct gtatttgttc acagtggttt cagagataaa gactttccct gcggcgaagc
    33061 aacgcagggg attaaataat gggggtagga ctatattgca ggtttgctgt ttcaggtttg
    33121 cagcttttta aagttctttg tttgcggatt tatgtggata actgaaacaa cgtggccatg
    33181 ttctgatgac tgatacgtgg ttttatggac agatatgccc ctctgagggg atttaaggtg
    33241 attactgcag attttgggct gagcggaacc agcgccgaaa gccccggagg ggctggcgat
    33301 gattcagtgc tgaaggaatg gtgctgtcta gtgcggcggt ggcgcagcca gcgtcagttc
    33361 aagctgacgc aactccctga tggccagtcg cttcagatgg tcatcggaac aaaaataggc
    33421 ttcatccggc ggcagacgct tcctgagata ctctgccatc tcatgaatct gctggtcggc
    33481 aggcagtttc ttcagacgtc tggcgcgctt actggctgcc gcttttgcac gacggtgttt
    33541 cagtgcatcc tggctgcgct gcagatacca gcgttttctg gccgcatgta cggagatatc
    33601 ttcatcctca cgcagtacgc cttcccggat gagttgctgg cggatttcac tttcacgcaa
    33661 ccgcttctgc tgctgttcgt gaagtttcac catgtcgacg cccagcatct gccagcctgc
    33721 cggtgttatc cagacgtaac gtggcagacg ctggcgggtt tcacggtccc acagggtttc
    33781 ctctgaaaca cccagcacac caaaacgtac ctgttcggcc agcaaacggg aaaggcggga
    33841 gaccgtcact tccagttccg gaataacctt ccccttgctg tctttcgggc tgatttctct
    33901 ggccagacgg gaaacactca tgcctacggt atgtgtgccc gcatcactga agctgaccag
    33961 aaccggccag atggcatcga ggaggcgttg tttttccgga cggaaagcat atttgcgacc
    34021 ggcatacgtt cgtttctgca cgtaaaaagg atgcagagac atgtgcatgc gcaggctctg
    34081 ctcgccggtc actgggtcct ttttcaccag acggttgtag gcgtgcccga gctgcccgct
    34141 cagcgcctta tagagctcag gacgatacca ggacggattt tcgcatttgg gtttggtgga
    34201 gtgctcaccg cgacggcgct tcgtgcgctt cctttccggt tcaaccagga aagtggtcgc
    34261 ccttcccgct tcatagtctt cccagaaacg gatctgctct tcgggtgcta actgactcca
    34321 gtg
//
