LOCUS       NZ_CP023791            40911 bp    DNA     circular CON 30-NOV-2023
DEFINITION  Enterococcus faecium strain Efaecium_ER04462.3A plasmid
            pER04462.3A.2, complete sequence.
ACCESSION   NZ_CP023791
VERSION     NZ_CP023791.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN07679730
            Assembly: GCF_002848685.1
KEYWORDS    RefSeq.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 40911)
  AUTHORS   Chako,K., Sullivan,M., Pak,T.J., Beckford,C., Altman,D., Ciferri,B.,
            Pak,T., Sebra,R., Kasarskis,A., Hamula,C. and van Bakel,H.
  TITLE     The genetic basis of emerging Vancomycin, Linezolid, and Daptomycin
            heteroresistance in a case of persistent Enterococcus faecium
            bacteremia
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 40911)
  AUTHORS   Chacko,K.I., Sullivan,M.J. and van Bakel,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-SEP-2017) Genetics and Genomic Sciences, Icahn School
            of Medicine, One Gustave L. Levy Place Box 1498, New York, NY 10029,
            USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 10-MAR-2016
            Assembly Method                   :: HGAP v. 2.2.0
            Expected Final Version            :: yes
            Genome Coverage                   :: 31.2611278x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/30/2023 17:04:14
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,101
            CDSs (total)                      :: 3,008
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 93
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 43 of 127
            Pseudo Genes (incomplete)         :: 73 of 127
            Pseudo Genes (internal stop)      :: 31 of 127
            Pseudo Genes (multiple problems)  :: 15 of 127
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP023791.1.
            Bacteria and source DNA available from Icahn School of Medicine at
            Mount Sinai.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..40911
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /strain="Efaecium_ER04462.3A"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /plasmid="pER04462.3A.2"
                     /geo_loc_name="USA: New York, NY"
                     /lat_lon="40.789990 N 73.953689 W"
                     /collection_date="2015"
                     /collected_by="Icahn School of Medicine at Mount Sinai"
     gene            1..1041
                     /locus_tag="CO995_RS15935"
                     /old_locus_tag="CO995_03018"
     CDS             1..1041
                     /locus_tag="CO995_RS15935"
                     /old_locus_tag="CO995_03018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_000997689.1"
                     /translation="MNDFNYYKSKEIYREKYYQMPKVFFTNEKYMDLSNDAKIAYMLLK
                     DRFDYSVKNNWVDSDDNIFFIFTVEELMKLLQCREGKVSKIKKELEKAGLLKQKRGRVN
                     KRDGKIESMPNLLYLGKPEVTNQDVFKIMEEEDNTDTTVIAKIANTAKPREINDTTVIA
                     KIANTAKSSHIKDSTVIAKIADNLFYSNSIDTNRHIIDTETDQLQNQVLLDNFVDIMKE
                     DSINTFVPENVLNLIKTFSSTYEDAQKTVQTIHNAKKKAEELEQTVVVYEELESYGIDA
                     DKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFVEKAIAAKLANEQRETFNELPTVS
                     TENWLE"
                     /name="replication initiator protein A"
     gene            complement(1657..2337)
                     /locus_tag="CO995_RS15940"
                     /old_locus_tag="CO995_03019"
     CDS             complement(1657..2337)
                     /locus_tag="CO995_RS15940"
                     /old_locus_tag="CO995_03019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_002343844.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIGADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKLYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            2483..2566
                     /locus_tag="CO995_RS15945"
     CDS             2483..2566
                     /locus_tag="CO995_RS15945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /GO_process="GO:0046677 - response to antibiotic [Evidence
                     IEA]; GO:0031556 - transcriptional attenuation by ribosome
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="WP_001814874.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
                     /name="23S rRNA methyltransferase attenuation leader
                     peptide"
     gene            2691..3428
                     /gene="erm(B)"
                     /locus_tag="CO995_RS15950"
                     /old_locus_tag="CO995_03020"
     ARG             2692..3425
                     /name="erm(B)"
                     /gene="erm(B)"
                     /gene_name="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /tool="amrfinderplus"
                     /drug_class="LINCOSAMIDE/MACROLIDE/STREPTOGRAMIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            <3598..3858
                     /locus_tag="CO995_RS15960"
                     /pseudo=""
     CDS             <3598..3858
                     /locus_tag="CO995_RS15960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /GO_component="GO:0005694 - chromosome [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003916 - DNA topoisomerase activity [Evidence IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
                     /name="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
     gene            4021..>4686
                     /locus_tag="CO995_RS15965"
                     /old_locus_tag="CO995_03022"
                     /pseudo=""
     CDS             4021..>4686
                     /locus_tag="CO995_RS15965"
                     /old_locus_tag="CO995_03022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558228.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element IS1182 family transposase"
                     /name="IS1182-like element IS1182 family transposase"
     gene            4722..4967
                     /locus_tag="CO995_RS15970"
                     /old_locus_tag="CO995_03023"
     CDS             4722..4967
                     /locus_tag="CO995_RS15970"
                     /old_locus_tag="CO995_03023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="WP_000567888.1"
                     /translation="MIDVNELLEEAIRETENLNDGEVFLVKDLFKGYVGNRIPRKDRLL
                     LGTLFLNHVSKMNGNLKAIEKTSSNQQRYKKTIDKF"
                     /name="single-stranded DNA-binding protein"
     gene            5070..5939
                     /locus_tag="CO995_RS15975"
                     /old_locus_tag="CO995_03024"
     CDS             5070..5939
                     /locus_tag="CO995_RS15975"
                     /old_locus_tag="CO995_03024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing protein"
                     /protein_id="WP_000228166.1"
                     /translation="MVDNIIKSVAEKLSSLSYIEGIVLGGSRARGTHTEDSDIDIGIYY
                     NSESFDINTINQFATKLDDEHRNNLVVPPGAWGDWINGGGWLVINGYHVDLILRDIKRV
                     EQIMKDTEHGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAETYPNA
                     LQKSLVNFFMFEAGFSLMFVKANSGTDDKYYIAGHVFRIVSCLNQVLFACNNAYCINEK
                     KAIKLLETFEHKPEKYTEKVNHIFEVLGISLFECYDMTEKLYNEVNEIVSEINNFLNEE
                     SSDERKQI"
                     /name="nucleotidyltransferase domain-containing protein"
     gene            5920..6654
                     /locus_tag="CO995_RS15980"
                     /old_locus_tag="CO995_03025"
     CDS             5920..6654
                     /locus_tag="CO995_RS15980"
                     /old_locus_tag="CO995_03025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]; GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_000662263.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGKR
                     VLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDFPE
                     ESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNEKGE
                     ILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPENMMD
                     IPGMADEMRRPMMLIVSAKKKM"
                     /name="class I SAM-dependent methyltransferase"
     gene            6687..7599
                     /gene="ant(6)"
                     /locus_tag="CO995_RS15985"
                     /old_locus_tag="CO995_03026"
                     /pseudo=""
     CDS             6687..7599
                     /gene="ant(6)"
                     /locus_tag="CO995_RS15985"
                     /old_locus_tag="CO995_03026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /name="ant(6)"
     gene            7596..8138
                     /gene="sat4"
                     /locus_tag="CO995_RS15990"
                     /old_locus_tag="CO995_03027"
     ARG             7597..8135
                     /name="sat4"
                     /gene="sat4"
                     /gene_name="streptothricin N-acetyltransferase Sat4"
                     /tool="amrfinderplus"
                     /drug_class="STREPTOTHRICIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            8231..9025
                     /gene="aph(3')-IIIa"
                     /locus_tag="CO995_RS15995"
                     /old_locus_tag="CO995_03028"
     ARG             8232..9022
                     /name="aph(3')-IIIa"
                     /gene="aph(3')-IIIa"
                     /gene_name="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            9301..9843
                     /locus_tag="CO995_RS16005"
                     /old_locus_tag="CO995_03029"
     CDS             9301..9843
                     /locus_tag="CO995_RS16005"
                     /old_locus_tag="CO995_03029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="WP_002321977.1"
                     /translation="MNRINRVTSILIQLQSKKIIPAKEIAQRFNISLRTVYRDIRTLEE
                     AGIPIGSEAGKGYFLVEGFLLPPVMFTAAEVGALITAGKFLNCHGDESFIKDFDSAMYK
                     IKSILKHGEKNYAQELENSINVYSTSGQKNTLADNVIAAIQTAICNKRVISIQYPASGG
                     QEPESRMIEPVLLQSFK"
                     /name="HTH domain-containing protein"
     gene            complement(9873..10542)
                     /locus_tag="CO995_RS16010"
                     /old_locus_tag="CO995_03030"
                     /pseudo=""
     CDS             complement(9873..10542)
                     /locus_tag="CO995_RS16010"
                     /old_locus_tag="CO995_03030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /name="IS6-like element IS1216 family transposase"
     gene            complement(<10613..12349)
                     /locus_tag="CO995_RS16015"
                     /old_locus_tag="CO995_03031"
                     /pseudo=""
     CDS             complement(<10613..12349)
                     /locus_tag="CO995_RS16015"
                     /old_locus_tag="CO995_03031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684984.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4158 domain-containing protein"
                     /name="DUF4158 domain-containing protein"
     gene            12495..13070
                     /locus_tag="CO995_RS16020"
                     /old_locus_tag="CO995_03032"
     CDS             12495..13070
                     /locus_tag="CO995_RS16020"
                     /old_locus_tag="CO995_03032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001226076.1"
                     /translation="MRKIGYIRVSSTNQNPSRQFQQLNEIGMDIIYEEKVSGATKDREQ
                     LQKVLDDLQEDDIIYVTDLTRITRSTQDLFELIDNIRDKKASLKSLKDTWLDLSEDNPY
                     SQFLITVMAGVNQLERDLIRMRQREGIELAKKEGKFKGRLKKYHKNHAGMNYAVKLYKE
                     GNMTVNQICEITNVSRASLYRKLSEVNN"
                     /name="recombinase family protein"
     gene            13284..13979
                     /gene="vanR-A"
                     /locus_tag="CO995_RS16025"
                     /old_locus_tag="CO995_03033"
     ARG             13285..13976
                     /name="vanR-A"
                     /gene="vanR-A"
                     /gene_name="vancomycin resistance response regulator
                     transcription factor VanR-A"
                     /tool="amrfinderplus"
                     /drug_class="GLYCOPEPTIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            13957..15111
                     /locus_tag="CO995_RS16030"
                     /old_locus_tag="CO995_03034"
     CDS             13957..15111
                     /locus_tag="CO995_RS16030"
                     /old_locus_tag="CO995_03034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance histidine kinase VanS-A"
                     /protein_id="WP_002305818.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGKL
                     GDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKYFD
                     EINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVMYLA
                     HDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRYNLQT
                     ITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFNNILKN
                     AAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSSDTGGAG
                     LGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
                     /name="vancomycin resistance histidine kinase VanS-A"
     gene            complement(15209..16501)
                     /locus_tag="CO995_RS16035"
                     /old_locus_tag="CO995_03035"
     CDS             complement(15209..16501)
                     /locus_tag="CO995_RS16035"
                     /old_locus_tag="CO995_03035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628567.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1251 family transposase"
                     /protein_id="WP_000122610.1"
                     /translation="MSYTHLIKETLDILDLSVTFNENCLTKEKYKGQICHIYRGNLIYT
                     AQECIHCKHQIASDIVRWGTTTVRLLMNDVSEYRTYLELKKQRFKCKACQRTFVADTSV
                     AKKHCFISEKVRWSVVTRLKKNTSMTEIAAQKNLSVSSVYRIMKRFYRPLNPFRTPLPK
                     VLCFDEFKSVRGVSGAMSFIMMDGQTQRLLDIVENRQLPFLKRYFSHFSREIREAVEWI
                     VIDMYAPYVSLVKKLFPKAQLIIDRFHIVQHIGRTFRNHRIKETNQLLKSKEQKHYQLG
                     KQLKRYWKLLQKDERKLDYTRRLWRPGFKAHLTETDIVDRLLKGSPALRVGYQLYQDFL
                     YAVKERDYVSFEELLTNNIMLPEGYQTTLRTFQKFLPQIKNALQQSYSNGPLECLNNHI
                     KVLKRNAYGFRSFYNFKLRIMIRHGNALIFN"
                     /name="ISL3-like element IS1251 family transposase"
     gene            16833..17801
                     /locus_tag="CO995_RS16040"
                     /old_locus_tag="CO995_03036"
     CDS             16833..17801
                     /locus_tag="CO995_RS16040"
                     /old_locus_tag="CO995_03036"
                     /EC_number="1.1.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="WP_001059542.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKSA
                     PFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAYSP
                     DSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKAVIE
                     RLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQRMKQ
                     GAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQFLLKL
                     QRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
                     /name="D-lactate dehydrogenase VanH-A"
     ARG             17777..18825
                     /name="vanA"
                     /gene="vanA"
                     /gene_name="glycopeptide resistance gene cluster; Van
                     ligase"
                     /tool="rgi"
                     /drug_class="glycopeptide antibiotic"
                     /identity="99.71"
                     /coverage="101.75"
     ARG             17795..18822
                     /name="vanA"
                     /gene="vanA"
                     /gene_name="D-alanine--(R)-lactate ligase VanA"
                     /tool="amrfinderplus"
                     /drug_class="GLYCOPEPTIDE"
                     /identity="99.71"
                     /coverage="100.0"
     gene            18831..19439
                     /locus_tag="CO995_RS16050"
                     /old_locus_tag="CO995_03038"
     CDS             18831..19439
                     /locus_tag="CO995_RS16050"
                     /old_locus_tag="CO995_03038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="WP_000402348.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTYE
                     LAESLLKAKELAATQGYGLLLWDGYRPNRAVNCFMQWAAQPENNLTKESYYPNIDRTEM
                     ISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEAQNR
                     RRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
                     /name="D-Ala-D-Ala dipeptidase VanX-A"
     gene            complement(19603..20283)
                     /locus_tag="CO995_RS16055"
                     /old_locus_tag="CO995_03039"
     CDS             complement(19603..20283)
                     /locus_tag="CO995_RS16055"
                     /old_locus_tag="CO995_03039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            20684..21595
                     /locus_tag="CO995_RS16060"
                     /old_locus_tag="CO995_03040"
     CDS             20684..21595
                     /locus_tag="CO995_RS16060"
                     /old_locus_tag="CO995_03040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="WP_001812592.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHLE
                     NSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLLDS
                     NIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGYSEH
                     NSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIRYVGL
                     PHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNLRYEIS
                     GNNIDGVIVTVFPGSTHTNSRR"
                     /name="D-Ala-D-Ala carboxypeptidase VanY-A"
     gene            21748..22233
                     /gene="vanZ-A"
                     /locus_tag="CO995_RS16065"
                     /old_locus_tag="CO995_03041"
     ARG             21749..22230
                     /name="vanZ-A"
                     /gene="vanZ-A"
                     /gene_name="glycopeptide resistance protein VanZ-A"
                     /tool="amrfinderplus"
                     /drug_class="GLYCOPEPTIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(22520..22849)
                     /locus_tag="CO995_RS16070"
                     /old_locus_tag="CO995_03042"
     CDS             complement(22520..22849)
                     /locus_tag="CO995_RS16070"
                     /old_locus_tag="CO995_03042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754864.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000754864.1"
                     /translation="MKKVCQVTVVHKEKVNGIKNKLDQKDFSNLLVLGKCFSDFSRIKI
                     FYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDILS
                     AIRVF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            23154..23483
                     /locus_tag="CO995_RS16075"
                     /old_locus_tag="CO995_03043"
     CDS             23154..23483
                     /locus_tag="CO995_RS16075"
                     /old_locus_tag="CO995_03043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000629052.1"
                     /translation="MITKTRKQGNSIMLTVPKEFDVPNGVEVEAKLVENGILYEFVEPK
                     KEFFDFSEDILADILSEGYSKQEILKEFRNRKNALTSAFKSIAEDTVANSKPMTKEELA
                     AEIGL"
                     /name="hypothetical protein"
     gene            23473..23760
                     /locus_tag="CO995_RS16080"
                     /old_locus_tag="CO995_03044"
     CDS             23473..23760
                     /locus_tag="CO995_RS16080"
                     /old_locus_tag="CO995_03044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000312842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_000312841.1"
                     /translation="MAYEILPSKHVIKYLKKLKEKTLKEQFLTIIYDEIAVRPHSGEQK
                     TGDLSGIWAIGFKYAGTTYRVAYEIKDNAVIPILLCGTHENFYEQLKKIR"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(24039..24602)
                     /locus_tag="CO995_RS16085"
                     /old_locus_tag="CO995_03045"
     CDS             complement(24039..24602)
                     /locus_tag="CO995_RS16085"
                     /old_locus_tag="CO995_03045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000017403.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000017403.1"
                     /translation="MSGYIYGYARVSTRSQELNRQLDLLNEQNCNEILTEKMTGTKAVR
                     PQLNRLKDKIRPGDTVIVESFSRLGRSTKDLIDLVTYFEEHHVKLVSLKENFDTSTPHG
                     RLMMTVFQAFSQFERDLIVERTKEGLKSARARGRKGGRPRVNQKDVDRAVKLYKSQVYS
                     VKEITEMTGISKATLYRYLKDNRE"
                     /name="recombinase family protein"
     gene            25245..26198
                     /locus_tag="CO995_RS16090"
                     /old_locus_tag="CO995_03046"
     CDS             25245..26198
                     /locus_tag="CO995_RS16090"
                     /old_locus_tag="CO995_03046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="WP_000222571.1"
                     /translation="MTYTHLTPNELVMIEAYFHQETPVAIVAKQLKRGRQTIYNVYNFL
                     KCGGTALEYFEQYKENKRRCGRTEIIFPAEEKEYIEKRSTEGWTPDVIIGRAERTFSCS
                     ISTLYRRFKTGEFNVLHLPMQGKRKPNGYKEKRGKQAFKRNISERKKDYVVFEEEFGHL
                     EGDTIVGIHHKSAVITLVERLSKAIIVLKPEGRKAVDIENSINEWLQSVPKNLFKSITF
                     DCGKEFSNWKSISNTNDIDIYFADPGTPSQRGLNEHSNGLLRKDGLPKEMDFNQVNQGF
                     ISSVASKRNHIPRKSLNYQTPLEVFLSYVNGKFCLA"
                     /name="IS30 family transposase"
     gene            26176..27651
                     /locus_tag="CO995_RS16095"
                     /old_locus_tag="CO995_03047"
     CDS             26176..27651
                     /locus_tag="CO995_RS16095"
                     /old_locus_tag="CO995_03047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-directed DNA polymerase"
                     /protein_id="WP_000443455.1"
                     /translation="MESFVSLNLTNNTSKKNQPKDIKDIVDTRMYKERDDLNYTLIINK
                     DGNYSWRPLVLLHPILYVDLVNCLTKEDHWEELKKRFSEFKKDKNINCYSIPVEASKGS
                     KRTDLGETILNWWEYFEQKSLAQNIKYQYCMFTDIADCYPSIYTHSITWAMYGKEKVKN
                     DENKCSGSLGDKIDKKISGMQHNQTNGIPQGSVLMDFVAEIVLGYVDLRLSKELKKLEN
                     LKDYKVLRYRDDYRIFSNNRNDLEQIMKVLSEVLYDLNFKLNSSKTKLSDDIIIDSIKK
                     DKLYWEEIKASIRMNATNLDGDREIRYSINLQKHLLEIKKLADKHPNSGQLKKALSEFN
                     KERIIKITSKPNDLLPLIGILVDIMINNPGSLPQCVLIIGQLLNFENESKAREIVEMII
                     NKYALKPNTEFMMIWFQRLTTIFGEMFDSVLSSEFVSKIKDPVSNQMFSVDWLNEDAKK
                     SFYEGTIKDEEKYIKMSKKIYITEFDDFNDYPF"
                     /name="RNA-directed DNA polymerase"
     gene            27784..28956
                     /locus_tag="CO995_RS16100"
                     /old_locus_tag="CO995_03048"
     CDS             27784..28956
                     /locus_tag="CO995_RS16100"
                     /old_locus_tag="CO995_03048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /protein_id="WP_000195429.1"
                     /translation="MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTEY
                     IQAKEYERTENRQSQRNGYYERSFTTRVGTLELKVPRTRDGHFSPTVFERYQRNEKALM
                     ASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLEPMVNEWQNRLLSEKNYPY
                     LMTDVLYIKVREENRVLSKSCHIAIGITKDGDREIIGFMIQSGESEETWTTFFEYLKER
                     GLQGTELVISDAHKGLVSAIRKSFTNVSWQRCQVHFLRNIFTTIPKKNSKSFREAVKGI
                     FKFTDINLAREAKNRLIHDYIDQPKYSKACASLDDGFEDAFQYTVQGNSHNRLKSTNLI
                     ERLNQEVRRREKIIRIFPNQTSANRLIGAVLMDLHDEWIYSSRKYINFDK"
                     /name="IS256-like element IS256 family transposase"
     gene            29321..>30784
                     /locus_tag="CO995_RS16105"
                     /old_locus_tag="CO995_03049"
                     /pseudo=""
     CDS             29321..>30784
                     /locus_tag="CO995_RS16105"
                     /old_locus_tag="CO995_03049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305144.1"
                     /GO_function="GO:0015666 - restriction
                     endodeoxyribonuclease activity [Evidence IEA]; GO:0009007 -
                     site-specific DNA-methyltransferase (adenine-specific)
                     activity [Evidence IEA]"
                     /GO_process="GO:0006306 - DNA methylation [Evidence IEA];
                     GO:0009307 - DNA restriction-modification system [Evidence
                     IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit M"
                     /name="type I restriction-modification system subunit M"
     gene            complement(30822..31502)
                     /locus_tag="CO995_RS16110"
                     /old_locus_tag="CO995_03050"
     CDS             complement(30822..31502)
                     /locus_tag="CO995_RS16110"
                     /old_locus_tag="CO995_03050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            complement(31556..32815)
                     /locus_tag="CO995_RS16115"
                     /old_locus_tag="CO995_03051"
     CDS             complement(31556..32815)
                     /locus_tag="CO995_RS16115"
                     /old_locus_tag="CO995_03051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086557923.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1251 family transposase"
                     /protein_id="WP_016171138.1"
                     /translation="MSYTHLIKETLDILDLSVTFNENCLTKEKYKGQICHIYRGNLIYT
                     AQECIHCKHQIASDIVRWGTTTVRLLMNDVSEYRTYLELKKQRFKCKACQRTFVADTSV
                     AKKHCFISEKVRWSVVTRLKKNTSMTEIAAQKNLSVSSVYRIMKRFYRPLNPFRTPLPK
                     VLCFDEFKSVRGVSGAMSFIMMDGQTQRLLDIVENRQLPFLKRYFSHFSREIREAVEWI
                     VIDMYAPYVSLVKKLFPKAQLIIDRFHIVQHIGRTFRNHRIKETNQLLKSKEQKHYQLG
                     KQLKRYWKLLQKDERKLDYTRRLWRPGFKAHLTETDIVDRLLKGSPALRVGYQLYQDFL
                     YAVKERDYVSFEELLTNNIMLPEGYQTTLRTFQKFLPQIKNALQQSYSNGPLECLNNHI
                     KVLKRNAYGFRSFYGSVAKF"
                     /name="ISL3-like element IS1251 family transposase"
     gene            complement(32965..33579)
                     /locus_tag="CO995_RS16120"
                     /old_locus_tag="CO995_03052"
     CDS             complement(32965..33579)
                     /locus_tag="CO995_RS16120"
                     /old_locus_tag="CO995_03052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_010782630.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRPV
                     FQEALDYVRDQDIFIVEAIDRLGRNYDEIITSVNYLKKKNVKLIITSLPIMAEAIGNPL
                     LDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQRRL
                     VYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
                     /name="recombinase family protein"
     gene            33893..34315
                     /locus_tag="CO995_RS16125"
                     /old_locus_tag="CO995_03053"
     CDS             33893..34315
                     /locus_tag="CO995_RS16125"
                     /old_locus_tag="CO995_03053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002288787.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELTP
                     LDRNGIAIGNPTNDLTVTENYLIVSPLLARAASKTIRVTGTMIFDKVGWPSRPPQSRNW
                     KEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
                     /name="hypothetical protein"
     gene            34325..34528
                     /locus_tag="CO995_RS16130"
                     /old_locus_tag="CO995_03054"
     CDS             34325..34528
                     /locus_tag="CO995_RS16130"
                     /old_locus_tag="CO995_03054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002299573.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKSI
                     SNLEDSEEKRKKRDQKTYQKEK"
                     /name="hypothetical protein"
     gene            34739..35323
                     /locus_tag="CO995_RS16135"
                     /old_locus_tag="CO995_03055"
     CDS             34739..35323
                     /locus_tag="CO995_RS16135"
                     /old_locus_tag="CO995_03055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_002299575.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPGL
                     EMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSSTGQ
                     LMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSGTPI
                     KTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
                     /name="recombinase family protein"
     gene            35492..36817
                     /locus_tag="CO995_RS16140"
                     /old_locus_tag="CO995_03056"
     CDS             35492..36817
                     /locus_tag="CO995_RS16140"
                     /old_locus_tag="CO995_03056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="WP_016171137.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRSD
                     NTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNIFR
                     RYVADEDLLIYSIDESILKVTKSLNLFTTEETRSQRRKKLAQMIQERIKEELGLIATVG
                     VGDNPLLAKLALDNEAKHNEGFIAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRLNQMG
                     ILSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQVLPRD
                     YTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLHIGTSILETRPGFSHQMKIPITDNT
                     KELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEENLDKIIDK
                     IRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGNGGIKND"
                     /name="Y-family DNA polymerase"
     gene            36810..37160
                     /locus_tag="CO995_RS16145"
                     /old_locus_tag="CO995_03057"
     CDS             36810..37160
                     /locus_tag="CO995_RS16145"
                     /old_locus_tag="CO995_03057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000568378.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRTSQNLAKEQMTTEE
                     IAEVLNAAVIKNRSVSIQKEERNAEGYYPEDIIGKILGSDELGIYVGKDKIHYDEIRHI
                     EFYQDNKWSRLE"
                     /name="hypothetical protein"
     gene            37157..37336
                     /locus_tag="CO995_RS16150"
                     /old_locus_tag="CO995_03058"
     CDS             37157..37336
                     /locus_tag="CO995_RS16150"
                     /old_locus_tag="CO995_03058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001021554.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAAA
                     GYHNFRFYIFPLYI"
                     /name="hypothetical protein"
     gene            37472..37762
                     /locus_tag="CO995_RS16155"
                     /old_locus_tag="CO995_03059"
     CDS             37472..37762
                     /locus_tag="CO995_RS16155"
                     /old_locus_tag="CO995_03059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000026576.1"
                     /translation="MSINTFVYSHPINVYIIKNLGITVEQFCELYAYPQGTVASWITRQ
                     RRIKSLPASFVYDLSLASSLNMSDVYEKLLSLEKEYDSFKIKHDKKIKKHI"
                     /name="hypothetical protein"
     gene            38060..39232
                     /locus_tag="CO995_RS16160"
                     /old_locus_tag="CO995_03060"
     CDS             38060..39232
                     /locus_tag="CO995_RS16160"
                     /old_locus_tag="CO995_03060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /protein_id="WP_000195429.1"
                     /translation="MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTEY
                     IQAKEYERTENRQSQRNGYYERSFTTRVGTLELKVPRTRDGHFSPTVFERYQRNEKALM
                     ASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLEPMVNEWQNRLLSEKNYPY
                     LMTDVLYIKVREENRVLSKSCHIAIGITKDGDREIIGFMIQSGESEETWTTFFEYLKER
                     GLQGTELVISDAHKGLVSAIRKSFTNVSWQRCQVHFLRNIFTTIPKKNSKSFREAVKGI
                     FKFTDINLAREAKNRLIHDYIDQPKYSKACASLDDGFEDAFQYTVQGNSHNRLKSTNLI
                     ERLNQEVRRREKIIRIFPNQTSANRLIGAVLMDLHDEWIYSSRKYINFDK"
                     /name="IS256-like element IS256 family transposase"
     gene            39462..40250
                     /locus_tag="CO995_RS16165"
                     /old_locus_tag="CO995_03061"
     CDS             39462..40250
                     /locus_tag="CO995_RS16165"
                     /old_locus_tag="CO995_03061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302898.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016887 - ATP hydrolysis activity [Evidence IEA]"
                     /GO_process="GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_000101106.1"
                     /translation="MARILSVANQKGGVSKTTTSVNLAACLKFVYGKNVLLVDIDPQGN
                     ATDNVGFDIDGTNQPTIYEVLKGEADITDAILDYKGIDVLPADIALSSAEREFTQVGSE
                     HRLKRVLQPIKDNYDYIIIDCPPSLGMLTVNAFTVSDEIIIPVEAAYFSLKGLIKLSET
                     IETVKEYTNDKLEVRGVLFTKYNKRYNISKEMTSAATEISRVIGAKIFKTYIRRTITVD
                     EAQAAGSDLINFNKPSTAEDDYKAFTEEYLKEVGDFDGRR"
                     /name="AAA family ATPase"
     gene            40237..40563
                     /locus_tag="CO995_RS16170"
                     /old_locus_tag="CO995_03062"
     CDS             40237..40563
                     /locus_tag="CO995_RS16170"
                     /old_locus_tag="CO995_03062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000796719.1"
                     /translation="MAEDNRSQAAVSRLLGNKNKKNFKSKEVEEIELTKKNISKVIKDQ
                     GSSVRTADSIRINPILMSALKYWTTIAESDKSKPDVIEDALLKSIPEEYLIEGYKLAKK
                     QNKI"
                     /name="hypothetical protein"
     ARG             16834..17798
                     /name="vanH-A"
                     /gene="vanH-A"
                     /gene_name="D-lactate dehydrogenase VanH-A"
                     /tool="amrfinderplus"
                     /drug_class="GLYCOPEPTIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             18832..19436
                     /name="vanX-A"
                     /gene="vanX-A"
                     /gene_name="D-Ala-D-Ala dipeptidase VanX-A"
                     /tool="amrfinderplus"
                     /drug_class="GLYCOPEPTIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             13958..15108
                     /name="vanS-A"
                     /gene="vanS-A"
                     /gene_name="vancomycin resistance histidine kinase VanS-A"
                     /tool="amrfinderplus"
                     /drug_class="GLYCOPEPTIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             20685..21592
                     /name="vanY-A"
                     /gene="vanY-A"
                     /gene_name="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /tool="amrfinderplus"
                     /drug_class="GLYCOPEPTIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             6743..7596
                     /name="ant(6)-Ia"
                     /gene="ant(6)-Ia"
                     /gene_name="aminoglycoside nucleotidyltransferase
                     ANT(6)-Ia"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="99.65"
                     /coverage="94.37"
     ARG             16834..17801
                     /name="vanH gene in vanA cluster"
                     /gene="vanH gene in vanA cluster"
                     /gene_name="vanH; glycopeptide resistance gene cluster"
                     /tool="rgi"
                     /drug_class="glycopeptide antibiotic"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             13285..13979
                     /name="vanR gene in vanA cluster"
                     /gene="vanR gene in vanA cluster"
                     /gene_name="glycopeptide resistance gene cluster; vanR"
                     /tool="rgi"
                     /drug_class="glycopeptide antibiotic"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             20685..21595
                     /name="vanY gene in vanA cluster"
                     /gene="vanY gene in vanA cluster"
                     /gene_name="vanY; glycopeptide resistance gene cluster"
                     /tool="rgi"
                     /drug_class="glycopeptide antibiotic"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             21749..22233
                     /name="vanZ gene in vanA cluster"
                     /gene="vanZ gene in vanA cluster"
                     /gene_name="vanZ; glycopeptide resistance gene cluster"
                     /tool="rgi"
                     /drug_class="glycopeptide antibiotic"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             13958..15112
                     /name="vanS gene in vanA cluster"
                     /gene="vanS gene in vanA cluster"
                     /gene_name="vanS; glycopeptide resistance gene cluster"
                     /tool="rgi"
                     /drug_class="glycopeptide antibiotic"
                     /identity="100.0"
                     /coverage="94.79"
     ARG             18832..19439
                     /name="vanX gene in vanA cluster"
                     /gene="vanX gene in vanA cluster"
                     /gene_name="vanX; glycopeptide resistance gene cluster"
                     /tool="rgi"
                     /drug_class="glycopeptide antibiotic"
                     /identity="99.5"
                     /coverage="100.0"
     ARG             7597..8138
                     /name="SAT-4"
                     /gene="SAT-4"
                     /gene_name="streptothricin acetyltransferase (SAT)"
                     /tool="rgi"
                     /drug_class="nucleoside antibiotic"
                     /identity="99.44"
                     /coverage="100.0"
     ARG             6740..7599
                     /name="aad(6)"
                     /gene="aad(6)"
                     /gene_name="ANT(6)"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="100.0"
                     /coverage="103.62"
     ARG             2692..3428
                     /name="ErmB"
                     /gene="ErmB"
                     /gene_name="Erm 23S ribosomal RNA methyltransferase"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; lincosamide antibiotic;
                     streptogramin antibiotic; streptogramin A antibiotic;
                     streptogramin B antibiotic"
                     /identity="98.37"
                     /coverage="98.79"
     Typing          2..1041
                     /name="rep_cluster_889"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 atgaatgatt ttaattatta caaatcaaaa gaaatttatc gtgaaaaata ttatcaaatg
       61 cctaaggtat tttttactaa cgaaaaatac atggatctat caaatgatgc aaaaattgct
      121 tatatgctac ttaaagatcg atttgattat tcagtcaaaa ataactgggt agattctgat
      181 gataatatat ttttcatatt cacagttgaa gaattaatga aattgttaca atgccgcgaa
      241 ggtaaagtat ctaaaatcaa aaaggaatta gaaaaagcag gtcttctgaa acagaagaga
      301 ggaagagtaa ataaacgtga cggtaagatt gaatccatgc ctaatttatt gtacttaggc
      361 aagccagaag taacgaatca agacgtcttt aaaatcatgg aagaggaaga caatactgat
      421 accaccgtaa ttgcgaaaat cgcaaatacg gcaaaaccgc gagaaatcaa tgataccacc
      481 gtaattgcga aaatcgcaaa tacggcaaaa tccagtcata tcaaggactc aaccgtaatt
      541 gcgaaaatcg cagacaatct attctattct aattctatag acactaatag acacataata
      601 gacactgaaa ctgatcagtt acaaaatcaa gttttactag ataacttcgt cgacatcatg
      661 aaagaggaca gtataaatac atttgtacca gaaaatgtat taaacttgat aaaaacattt
      721 tctagtactt acgaagacgc tcaaaaaacc gtccaaacta ttcataatgc aaagaaaaaa
      781 gctgaagaat tagagcaaac agttgttgtt tatgaagaac tggaatctta tggaattgat
      841 gctgacaaag gattatatat gactttgctg aaagcttatc aaaaacaaaa aactgaaaaa
      901 gtaaacaatt tgcagaatct aattttcgtt tatgtaaaaa attggtttgt cgaaaaagct
      961 attgcggcaa agcttgcaaa cgaacaaaga gaaacattta acgaattacc aacagttagt
     1021 acggaaaatt ggctagagta gttgataaaa agcgatcact ataaaaatga tcaattttaa
     1081 attagaactt ttttatgatt ttaattttat tacaaatgtt acaaataaat agctattatt
     1141 ccggagtttt tagattaaaa gtttatgaaa acaatcacaa acgtaggttt taaagtcata
     1201 atcgttagat attttagtta tttttcattc aaaaaaatag ggaactagtg tttgcatatg
     1261 tgcttttttg agttataata attcatgaag agaggtaatt cacttatttc cccaagctga
     1321 aaagcctgat attacttctt ttcaggcagt gctgctaata ttcaattaca cttttttgta
     1381 tatttttagt tgttttaaat ttaattgtct gatatgcttg tgatgaattg attttcgttc
     1441 tgcacttttg gacgataaat tgtgataatt gaaaatacaa aaaaaagaaa ggcccctgta
     1501 aggctcggga gactggtaat ctccgtcagt gtcctacagg aaagcattaa gatgacgcct
     1561 taatgcgtgc ccttcagtgt tacggtatta cccgcaacgg acggttctgt tgcaaagttt
     1621 taaataaaga ataaaatccc ttacggtatc tatgatttaa gctgggattc ccaataatac
     1681 cttgatttca gtacagaccg aaaacccgaa gagagtgcct tcttttcggg ttttcttata
     1741 taatcctcga atggcttcca tgcctttaat cgtggtagag gcagtgcgta aacttcgata
     1801 taatttattg cgtctcttta ctggacgatg gtcttgttca atcaaattat tcaggtattt
     1861 aatggtacga tgttctgtcc cttgataaaa gccgtattct tttagtttct taaaggcact
     1921 tgtaatagag ggggctttat ctgtgactac aaccttcggt tcatcaaact gcttcactaa
     1981 ccgcttaaga aaagcatagg ctgcttgtgt gtcccgtttt ttacgtaacc aaatatccaa
     2041 ggttaaacca tctgcaccga tggctcgata caaataatgc cattttcctt taattttgat
     2101 gtacgtttca tccattttcc atgaataaaa ggatttttta tttttctttt tccaaatttg
     2161 atagagtagt ttgccatatt cttgcaccca acgataaatc gtcgtatgag aaacgttaat
     2221 gccacgatca tataagattt cttgaacttc acgatagcta aggttataac gaagatagta
     2281 gcccacggct acaataatca catcctgctg aaattgcttt cctttaaaat gattcatcgt
     2341 cattcctcct gctatctttt tctattattc taccttattt gatagtagat ttaaaacttt
     2401 gcaacagaac cattttgtgt ataataggaa ttgaagttaa attagatgct aaaaatttgt
     2461 aattaagaag gagggattcg tcatgttggt attccaaatg cgtaatgtag ataaaacatc
     2521 tactgttttg aaacagacta aaaacagtga ttacgcagat aaataaatac gttagattaa
     2581 ttcctaccag tgactaatct tatgactttt taaacagata actaaaatta caaacaaatc
     2641 gtttaacttc tgtatttatt tacagatgta ataacttcag gagtgattac atgaacaaaa
     2701 atataaaata ttctcaaaac tttttaacga gtgaaaaagt actcaaccaa ataataaaac
     2761 aattgaattt aaaagaaacc gataccgttt acgaaattgg aacaggtaaa gggcatttaa
     2821 cgacgaaact ggctaaaata agtaaacagg taacgtctat tgaattagac agtcatctat
     2881 tcaacttatc gtcagaaaaa ttaaaactga acattcgtgt cactttaatt caccaagata
     2941 ttctacagtt tcaattccct aacaaacaga ggtataaaat tgttgggagt attccttacc
     3001 atttaagcac acaaattatt aaaaaagtgg tttttgaaag ccatgcgtct gacatctatc
     3061 tgattgttga agaaggattc tacaagcgta ccttggatat tcaccgaaca ctagggttgc
     3121 tcttgcacac tcaagtctcg attcagcaat tgcttaagct gccagcggaa tgctttcatc
     3181 ctaaaccaaa agtaaacagt gtcttaataa aacttacccg ccataccaca gatgttccag
     3241 ataaatattg gaagctatat acgtactttg tttcaaaatg ggtcaatcga gaatatcgtc
     3301 aactgtttac taaaaatcag tttcatcaag caatgaaaca cgccaaagta aacaatttaa
     3361 gtaccgttac ttatgagcaa gtattgtcta tttttaatag ttatctatta tttaacggga
     3421 ggaaataatt ctatgagtcg cttttttaaa tttggaaagt tacacgttac taaagggaat
     3481 ggagataaat tattagatat actactgaca gcttccaaga agctaaagag gtccctagcg
     3541 cctacgggga atttgtatcg ataaggggta caaattccca ctaagcgctc gggacccctt
     3601 gtaggaaaat gtcctaagtg tggcaacaat attgtattaa aaaaatcgtt ttatggttgt
     3661 tcaaattatc ctgaatgtaa gtttacttta gctgaacatt ttagaaagaa aaaactaacc
     3721 aaaacgaatg taaaagaatt actggaggga aaagaaaccc tggtaaaagg aatcaaaaac
     3781 aaagagaaaa agccctacaa tgccgttgta aaaattgggg aaaagggata tattgatttt
     3841 atctcttttt caaaataaac atggggctga cccaaaagta gctcctatat gaaaaataga
     3901 ggtctttcca tttagatagt agtggaaaga cctctattta tcttttgaaa gtgaatacaa
     3961 aaataaagca cactctgcta taatataggt gattaatcca tttgagagag gtgctttatc
     4021 atgtatcaaa attataccat aaaccaactt tgtttgccta tagatcttga aattaaatta
     4081 gaagaaaatg attttgctca tgccattgtg cagtttgttg actctattcc cgatgaagtc
     4141 tttcttcctt attatcaatc tatgggtaga ccccaatatc atcctcgtat gctactttcc
     4201 attattcttt gtgcctatat tcaaggggtt tattcgggcc gccaaataca aaatatgctg
     4261 atagatagta ttcggatgcg ctacttatct caagagcaat tccctaactt tcgtactatt
     4321 aatcgttttc gcgttcatcc gattatgaac gatattctag atcattcatt tgttcaattt
     4381 cgtgagctac tggttcaaag tggcttaatc agtggcagtg ctctatacat tgatggtaca
     4441 aaaattgaag cggatgcgaa taaatactct ttcgtttgga aaaaaagtat tttaaagtat
     4501 aaggatagcc ttgatcaaaa agcccttgaa aactaccaac aaatggtgga aacaaaaatc
     4561 ttacctgagt taatagatga tttaaaggat gaactttcta tagaagagat tgaaaggatt
     4621 cgtcaatctt tggaagaaaa ggaaaatcaa ttaattgaag cgattgacca aaccgaaaca
     4681 gtagaagggg gctgacccat tattaataag gagtggacaa catgattgat gtaaatgagc
     4741 tattggaaga agctattaga gaaactgaaa atctaaatga tggcgaagtt tttcttgtta
     4801 aagatttatt caagggatat gtggggaata ggatacccag aaaggatcga cttctgcttg
     4861 gaacgttatt tttaaaccat gttagcaaaa tgaatggtaa tttaaaggct attgaaaaga
     4921 cttcatctaa tcagcagagg tataaaaaga caattgataa gttttaacta tcttttgtga
     4981 aattaaaaaa attataaata tgttgagtag aagcaaaaga tttggcttgg aatttttaca
     5041 gcagtgaatc gataaaagga gcatgcttga tggtagataa tattattaaa tcagtagcag
     5101 agaaattatc ctctctgtct tatatagaag gtattgtttt aggtggttca cgtgcaaggg
     5161 gcacccatac agaggattcg gatatagata tcggcatcta ttacaattca gaatcatttg
     5221 acataaatac tattaatcaa ttcgctacaa agctggatga tgagcataga aataaccttg
     5281 ttgtacctcc cggagcatgg ggtgattgga ttaatggcgg cggatggtta gtcataaacg
     5341 ggtatcatgt ggatttaatt ttacgtgata ttaaacgtgt ggaacaaata atgaaagata
     5401 cagagcacgg aattgttact gccaattatc agactgggca tccccatggt tatattagtg
     5461 caatgtatcg aggagaatta gcgattagca aaatactata tgctaagaat gaaagcttat
     5521 gcgaattaaa aaaacaggca gaaacttatc ccaatgcttt gcagaaaagt ttagttaact
     5581 tttttatgtt tgaagcaggg ttctctttaa tgtttgtaaa agcaaattcg ggaacagacg
     5641 ataaatatta tattgcgggt catgtttttc gtatagtttc atgtttaaat caagtgttat
     5701 ttgcatgtaa taatgcttat tgtatcaacg aaaagaaagc tataaaactg cttgaaactt
     5761 ttgaacataa acctgaaaaa tataccgaga aggtaaatca tatttttgaa gtactcggta
     5821 tctcactttt tgaatgctac gacatgaccg agaagcttta taatgaagtg aatgaaattg
     5881 tatcggagat aaataacttt ttaaacgagg agagttcaga tgaaagaaaa caaatatgat
     5941 gataatatat tttttcaaaa atacagtcaa atgagtcgct cgcagaaagg actggctggt
     6001 gcgggagaat gggagacttt gaaaaagatg ctacctgatt ttaagggtaa gcgtgtgctt
     6061 gatttaggat gcggctatgg atggcactgt atatatgcga tggaaaacgg tgcttcctct
     6121 gtagtaggtg ttgatatttc tcataaaatg ctcgaagtag caaaaggaaa aacccatttt
     6181 ccacagattg aatatgaatg ctgtgccata gaagatgtgg atttcccaga ggagagcttt
     6241 gatgtaatac taagttcgct tgcgtttcat tatgtagcag actatgagaa tttaataaaa
     6301 aagatatata ggatgctgaa ggctggtggc aatttagttt ttacagttga acatcctgtt
     6361 tttactgctc atggaacaca agactggtat tataacgaaa aaggagaaat actgcatttc
     6421 ccggtggaca attattatta tgagggcaaa cggacagcta tgtttttgga agaaaaggtt
     6481 acaaaatatc atagaacact gaccacatat ctaaatacac tgctttcaaa tagttttata
     6541 ataaatcaga ttgtggagcc acagccgcca gagaacatga tggatattcc ggggatggcg
     6601 gatgaaatgc gacgcccaat gatgctgatt gtatcggcaa aaaagaagat gtaataatat
     6661 agaaaaaata aacgaggagt atgtaaatga gatcagaaaa agaaatgatg gatttagtac
     6721 tttctttagc agaacaggat gaacgaacgt attcgaattg tgacccttga ggggtcacgc
     6781 gcaaatatta atatacctaa agatgaattt caggattatg atattacata ttttgtaagt
     6841 gatatagaac cgtttatatc taatgatgac tggcttaatc aatttgggaa tataataatg
     6901 atgcaaaagc cggaggatat ggaattattc ccacctgaag aaaagggatt ttcctatctt
     6961 atgctatttg atgattacaa taaaattgat cttaccttat tgcccttgga agagttagat
     7021 aattacctaa agggcgataa attaataaag gttctaattg ataaagattg tagaattaaa
     7081 agggacatag ttccgactga tatagattat catgtaagaa agccaagcgc aagggagtat
     7141 gatgattgct gcaatgaatt ttggaatgta acaccttatg ttattaaagg attgtgccgt
     7201 aaggaaattt tatttgctat tgatcatttt aatcagattg ttcgccatga gctgctgaga
     7261 atgatatcat ggaaggtcgg catcgaaaca ggctttaaat taagtgtagg caagaactat
     7321 aagtttattg aaaggtatat atccgaggat ttgtgggaga aacttttgtc cacctaccgg
     7381 atggattcct atgaaaacat atgggaagca ttatttctat gccatcaatt gttcagggcg
     7441 gtatccggtg aggtggcgga aaggcttcat tatgcctatc cggagtatga taggaatata
     7501 acaaaatata ccagggacat gtataaaaaa tacactggta aaaccggctg cctggatagc
     7561 acatatgccg ctgatataga agagaggcgg gaacagtgat tacagaaatg aaagcagggc
     7621 acctgaaaga tatcgataaa cccagcgaac catttgaggt gataggtaag attataccga
     7681 ggtatgaaaa cgagaattgg acctttacag aattactcta tgaagcgcca tatttaaaaa
     7741 gctaccaaga cgaagaggat gaagaggatg aggaggcaga ttgccttgaa tatattgaca
     7801 atactgataa gataatatat ctttactacc aagacgataa atgcgtcgga aaagttaaac
     7861 tgcgaaaaaa ttggaaccgg tacgcttata tagaagatat cgccgtatgt aaggatttca
     7921 gggggcaagg cataggcagc gcgcttatca atatatctat agaatgggca aagcataaaa
     7981 acttgcatgg actaatgctt gaaacccagg acaataacct tatagcttgt aaattctatc
     8041 ataattgtgg tttcaaaatc ggctccgtcg atactatgtt atacgccaac tttgaaaaca
     8101 actttgaaaa agctgttttc tggtatttaa ggttttagaa tgcaaggaac agtgaattgg
     8161 agttcgtctt gttataatta gcttcttggg gtatctttaa atactgtaga aaagaggaag
     8221 gaaataataa atggctaaaa tgagaatatc accggaattg aaaaaactga tcgaaaaata
     8281 ccgctgcgta aaagatacgg aaggaatgtc tcctgctaag gtatataagc tggtgggaga
     8341 aaatgaaaac ctatatttaa aaatgacgga cagccggtat aaagggacca cctatgatgt
     8401 ggaacgggaa aaggacatga tgctatggct ggaaggaaag ctgcctgttc caaaggtcct
     8461 gcactttgaa cggcatgatg gctggagcaa tctgctcatg agtgaggccg atggcgtcct
     8521 ttgctcggaa gagtatgaag atgaacaaag ccctgaaaag attatcgagc tgtatgcgga
     8581 gtgcatcagg ctctttcact ccatcgacat atcggattgt ccctatacga atagcttaga
     8641 cagccgctta gccgaattgg attacttact gaataacgat ctggccgatg tggattgcga
     8701 aaactgggaa gaagacactc catttaaaga tccgcgcgag ctgtatgatt ttttaaagac
     8761 ggaaaagccc gaagaggaac ttgtcttttc ccacggcgac ctgggagaca gcaacatctt
     8821 tgtgaaagat ggcaaagtaa gtggctttat tgatcttggg agaagcggca gggcggacaa
     8881 gtggtatgac attgccttct gcgtccggtc gatcagggag gatatcgggg aagaacagta
     8941 tgtcgagcta ttttttgact tactggggat caagcctgat tgggagaaaa taaaatatta
     9001 tattttactg gatgaattgt tttagtacct agatttagat gtctaaaaag ctttaactac
     9061 aagcttttta gacatctaat cttttctgaa gtacatccgc aactgtccat actctgatgt
     9121 tttatatctt ttctaaaagt tcgctagata gagttctata ttagagatgt aaagagtttt
     9181 ggtgaagagg tttgtgagta tggcttttat aaccagggtg caatgagaag cactaacagc
     9241 agctagctta agaacgcata ggatatactt tttatggaag tcacagagga ggaataaaat
     9301 ttgaacagga ttaacagagt aacctctatt cttattcagc tgcaatcaaa aaaaataatt
     9361 cctgccaaag aaattgcaca gcgatttaat ataagcttaa ggacagttta cagagatatc
     9421 cggacacttg aagaagccgg aataccaatt ggatctgagg ccggaaaagg atattttctt
     9481 gtagagggct tcctacttcc gccggtaatg tttacagcgg cggaagtggg tgcattgatt
     9541 acagcaggga aatttttaaa ttgccatgga gatgaatcat ttataaagga ttttgattca
     9601 gctatgtata aaatcaaatc tattttgaag catggtgaaa aaaactatgc acaggagttg
     9661 gagaacagta ttaacgtgta cagcacatct ggacagaaaa atacattggc ggataacgtt
     9721 attgcagcaa ttcagactgc aatctgcaat aaaagggtaa tatcaattca atatcctgca
     9781 tcaggagggc aagaaccgga aagcagaatg atagagccgg ttctgttgca aagttttaaa
     9841 taaagaataa aatcccttac ggtatctatg atttaagctg ggattcccaa taataccttg
     9901 atttcagtac agaccgaaaa cccgaagaga gtgcgttttc ttatataatc ctcgaatggc
     9961 ttccatgcct ttaatcgtgg tagaggcagt gcgtaaactt cgatagaatt tattgcgtct
    10021 ctttactgga cgatggtctt gttcaatcaa attattcagg tatttaatgg tacgatgttc
    10081 tgtcccttga taaaagccgt attcttttag tttcttaaag gcacttgtaa tagagggggc
    10141 tttatctgtg actacaacct tcggttcatc aaactgcttc actaaccgct taagaaaagc
    10201 ataggctgct tgtgtgtccc gttttttacg taaccaaata tccaaggtta aaccatctgc
    10261 atcgatggct cgatacaaat aatgccattt tcctttaatt ttgatgtacg tttcatccat
    10321 tttccatgaa taaaaggatt ttttattttt ctttttccaa atttgataga gtagtttgcc
    10381 atattcttgc acccaacgat aaatcgtcgt atgagaaacg ttaatgccac gatcatataa
    10441 gatttcttga acttcacgat agctaaggtt ataacgaaga tagtagccca cggctacaat
    10501 aatcacatcc tgctgaaatt gctttccttt aaaatgattc atcgtcattc ctcctgctat
    10561 ctttttctat tattctacct tatttgatag tagatttaaa actttgcaac agaacccttg
    10621 gtagcatctg ataaaggctt gcactaaatt tttttgcttc ttctggaaca tctttttcta
    10681 agcgtgcaag tgatagcttt cctttttcaa gagaaacccc atctaactta ttggaattgg
    10741 cagctaacca ctttaacctt tcattaaagc tgctggttct ctccgttata taatcttcga
    10801 atgataaact aactgataat ctcgtattcc ccttcgattg attccatgta tcttccgaaa
    10861 acaaatattc ctcaaaatcc ctatattgtc tgctgccaac aatggaaaca tctcctgccc
    10921 gaacatgctc ccgaagttct gttaaaacag ccatttcata gtaatgacga ttaattgttg
    10981 taccatcatc ctcgtataaa tgtcttttcc atcgttttga aataaaatcc acaggtgagt
    11041 catcaggcac ttttcgcttt ccagattcgt tcattcctcg gataatctca acagcttgta
    11101 aaagtggctc atttgccttt gtagaatgaa attccaatac tcttaatagc gttggcgtat
    11161 attttcttag tgaataaaac cgtttttgca gtaagtctaa ataatcatag tcggcaggac
    11221 gtgcaagttc ctgagcctct tctactgaag agacaaaggt attccattca ataaccgatt
    11281 ctaaaacctt aaaaacgtct aatttttcct ctcttgcttt aattaatgct tgtccgatgt
    11341 tcgtaaagtg tataactttc tcatttagct ttttaccgtt ttgtttctgg atttcctctt
    11401 gagccttacg accttttgat aacaaactaa gtatttgcct atcatgaatt tcaaacgctt
    11461 tatccgttag ctcctgagta agttgtaata aatagatggt taatatcgaa taacgtttat
    11521 tttcttgaaa gtcacggaat gcatacggct cgtatcttga gcctaagcga gacagctgca
    11581 acaggcggtt acggtgcaaa tgactaattt gcactgtttc taaatccatt cctcgtatgt
    11641 attcgagtcg ttctattatt tttagaaaag tttcgggtga aggatgaccc ggtggctctt
    11701 ttaaccaacc caatatcgtt ttattggatt cggatggatg ctgcgaggta ataatccctt
    11761 caagcttttc tttttgctca tttgttagag atttactaac cgtattaaat agcttctttt
    11821 cagccattgc ccttgcttcc cacaccattc tttcaagtgt agtgatagca ggcagtataa
    11881 ttttgttttt tcttagaaaa tctatgcatt catgcagtag atgaatggca tcaccatttt
    11941 ccaaagctaa ttgatgaagg tacttaaatg tcattcgata ttcactcagg gtaaaagtta
    12001 caaagtcgta ttcacttcga atttctttca aatgatccca aagtgtattt tccctttgag
    12061 gataatgatc aagcgaggat ggactaacac caatctgttt cgatatatat tgtatgaccg
    12121 aatctgggat gcttttgata tgagtgtatg gccaaccggg ataccgaaga acagctaatt
    12181 gaacagcaaa tcctaaacgg ttttcttccc tccttcgctt attaactatt tctaaatccc
    12241 gtttggaaaa agtgaagtag gtccccagta tccattcatc ttcagggatt tgcataaaag
    12301 cctgtctctg ttccggtgta agcaattctc tacctctcgc aattttcatt cagtatcatt
    12361 ccatttctgt attttcaatt tattagttca attatatatc aatagagtgt actctattga
    12421 tacaaatgta gtagactgat aaaatcatag ttaagagcgt ctcataagac ttgtctcaaa
    12481 aatgaggtga tattttgcgg aaaatcggtt atattcgtgt cagttcgact aaccagaatc
    12541 cttcaagaca atttcagcag ttgaacgaga tcggaatgga tattatatat gaagagaaag
    12601 tttcaggagc aacaaaggat cgcgagcaac ttcaaaaagt gttagacgat ttacaggaag
    12661 atgacatcat ttatgttaca gacttaactc gaatcactcg tagtacacaa gatctatttg
    12721 aattaatcga taacatacga gataaaaagg caagtttaaa atcactaaaa gatacatggc
    12781 ttgatttatc agaagataat ccatacagcc aattcttaat tactgtaatg gctggtgtta
    12841 accaattaga gcgagatctt attcggatga gacaacgtga agggattgaa ttggctaaga
    12901 aagaaggaaa gtttaaaggt cgattaaaga agtatcataa aaatcacgca ggaatgaatt
    12961 atgcggtaaa gctatataaa gaaggaaata tgactgtaaa tcaaatttgt gaaattacta
    13021 atgtatctag ggcttcatta tacaggaaat tatcagaagt gaataattag ccattctgta
    13081 ttccgctaat gggcaatatt tttaaagaag aaaaggaaac tataaaatat taacagcctc
    13141 ctagcgatgc cgaaaagccc tttgataaaa aaagaatcat catcttaaga aattcttagt
    13201 catttattat gtaaatgctt ataaattcgg ccctataatc tgataaatta ttaagggcaa
    13261 acttatgtga aagggtgata actatgagcg ataaaatact tattgtggat gatgaacatg
    13321 aaattgccga tttggttgaa ttatacttaa aaaacgagaa ttatacggtt ttcaaatact
    13381 ataccgccaa agaagcattg gaatgtatag acaagtctga gattgacctt gccatattgg
    13441 acatcatgct tcccggcaca agcggcctta ctatctgtca aaaaataagg gacaagcaca
    13501 cctatccgat tatcatgctg accgggaaag atacagaggt agataaaatt acagggttaa
    13561 caatcggcgc ggatgattat ataacgaagc cctttcgccc actggagtta attgctcggg
    13621 taaaggccca gttgcgccga tacaaaaaat tcagtggagt aaaggagcag aacgaaaatg
    13681 ttatcgtcca ctccggcctt gtcattaatg ttaacaccca tgagtgttat ctgaacgaga
    13741 agcagttatc ccttactccc accgagtttt caatactgcg aatcctctgt gaaaacaagg
    13801 ggaatgtggt tagctccgag ctgctatttc atgagatatg gggcgacgaa tatttcagca
    13861 agagcaacaa caccatcacc gtgcatatcc ggcatttgcg cgaaaaaatg aacgacacca
    13921 ttgataatcc gaaatatata aaaacggtat ggggggttgg ttataaaatt gaaaaataaa
    13981 aaaaacgact attccaaact agaacgaaaa ctttacatgt atatcgttgc aattgttgtg
    14041 gtagcaattg tattcgtgtt gtatattcgt tcaatgatcc gagggaaact tggggattgg
    14101 atcttaagta ttttggaaaa caaatatgac ttaaatcacc tggacgcgat gaaattatat
    14161 caatattcca tacggaacaa tatagatatc tttatttatg tggcgattgt cattagtatt
    14221 cttattctat gtcgcgtcat gctttcaaaa ttcgcaaaat actttgacga gataaatacc
    14281 ggcattgatg tacttattca gaacgaagat aaacaaattg agctttctgc ggaaatggat
    14341 gttatggaac aaaagctcaa cacattaaaa cggactctgg aaaagcgaga gcaggatgca
    14401 aagctggccg aacaaagaaa aaatgacgtt gttatgtact tggcgcacga tattaaaacg
    14461 ccccttacat ccattatcgg ttatttgagc ctgcttgacg aggctccaga catgccggta
    14521 gatcaaaagg caaagtatgt gcatatcacg ttggacaaag cgtatcgact cgaacagcta
    14581 atcgacgagt tttttgagat tacacggtat aacctacaaa cgataacgct aacaaaaacg
    14641 cacatagacc tatactatat gctggtgcag atgaccgatg aattttatcc tcagctttcc
    14701 gcacatggaa aacaggcggt tattcacgcc cccgaggatc tgaccgtgtc cggcgaccct
    14761 gataaactcg cgagagtctt taacaacatt ttgaaaaacg ccgctgcata cagtgaggat
    14821 aacagcatca ttgacattac cgcgggcctc tccggggatg tggtgtcaat cgaattcaag
    14881 aacactggaa gcatcccaaa agataagcta gctgccatat ttgaaaagtt ctataggctg
    14941 gacaatgctc gttcttccga tacgggtggc gcgggacttg gattggcgat tgcaaaagaa
    15001 attattgttc agcatggagg gcagatttac gcggaaagca atgataacta tacgacgttt
    15061 agggtagagc ttccagcgat gccagacttg gttgataaaa ggaggtccta agagatgtat
    15121 ataattttgg ctctttgtca aatgatgttg gtaaagagaa atcttagaat aattggagat
    15181 caagtggatc agttcctctt gatctttttt agttgaaaat caatgcgttg ccatgacgaa
    15241 tcatgatgcg caatttgaaa ttataaaagc tacgaaagcc atatgcattt cgttttaaca
    15301 ctttgatatg gttgttcaga cattcaagtg ggccatttga ataactttgt tgtaaagcat
    15361 ttttgatttg tggcagaaat ttctggaacg ttctcaaggt cgtctgatag ccttcgggaa
    15421 gcatgatatt attggtaagt agttcttcaa acgatacgta gtctcgttcc tttacagcgt
    15481 aaagaaagtc ttgatataac tgatagccta cacgcaaagc agggctccct ttcagtaagc
    15541 gatccacaat atcggtctct gttaaatgag ctttgaagcc aggtcgccaa aggcgtcgag
    15601 tataatcaag cttgcgttca tctttttgaa gaagtttcca gtatcttttt aattgcttac
    15661 ctaattgata gtgtttttgt tctttgcttt ttaatagttg gttcgtttct ttgattcgat
    15721 gattgcgaaa ggtacgacca atatgttgga cgatgtgaaa ccggtcaata atcagctgtg
    15781 cttttggaaa cagcttttta acgagcgata cataaggagc gtacatatca atcacgatcc
    15841 attcgaccgc ttcacgaatt tctcgtgaaa aatgactaaa ataacgtttt aaaaaaggca
    15901 gttgtcggtt ctcgacaatg tccaataagc gctgtgtttg tccatccatc atgatgaaac
    15961 tcatagcacc tgaaacaccc cgaactgatt tgaattcatc aaaacaaagt accttaggta
    16021 acggtgtccg aaaaggattc aacggacgat aaaatcgctt cataatacgg taaacagaag
    16081 agaccgatag atttttctga gcggcgatct ctgtcattga ggtatttttt ttcagacgag
    16141 tcacgacaga ccagcggact ttctcactga tgaaacaatg ttttttcgca acagaagtat
    16201 ctgcgacaaa ggtccgctga caagctttgc atttgaagcg ttgctttttc aattcgaggt
    16261 aggtacggta ttcagaaaca tcgttcatta acaaccggac ggttgttgta ccccaacgca
    16321 caatatctga agcaatctgg tgtttacagt ggatgcattc ttgggctgta taaatcaagt
    16381 ttccacgata aatatgacag atttgccctt tgtatttttc ttttgtgaga caattttcgt
    16441 taaaagtaac tgataagtct agaatatcta atgtttcttt gataaggtga gtgtaagaca
    16501 tcttgattcc tccttttggg ttggttcgcc aaattaattc taaaggattt caaggtgtct
    16561 tttctatatg ttttggaaaa taaaaaagat gctggtgtca tccaccaaca tcaaaaagta
    16621 tagagccata attttttagg aaaatctcaa ggttatcttt actttttctt aggaaattaa
    16681 caatttaata ttaagaaacg gctcgttctt acacggtaga cttaataccg taagaacgag
    16741 ccgttttcgt tcttcagaga aagatttgac aagattacca ttggcatccc cgttttattt
    16801 ggtgcctttc acagaaaggg ttggtcttaa ttatgaataa catcggcatt actgtttatg
    16861 gatgtgagca ggatgaggca gatgcattcc atgctctttc gcctcgcttt ggcgttatgg
    16921 caacgataat taacgccaac gtgtcggaat ccaacgccaa atccgcgcct ttcaatcaat
    16981 gtatcagtgt gggacataaa tcagagattt ccgcctctat tcttcttgcg ctgaagagag
    17041 ccggtgtgaa atatatttct acccgaagca tcggctgcaa tcatatagat acaactgctg
    17101 ctaagagaat gggcatcact gtcgacaatg tggcgtactc gccggatagc gttgccgatt
    17161 atactatgat gctaattctt atggcagtac gcaacgtaaa atcgattgtg cgctctgtgg
    17221 aaaaacatga tttcaggttg gacagcgacc gtggcaaggt actcagcgac atgacagttg
    17281 gtgtggtggg aacgggccag ataggcaaag cggttattga gcggctgcga ggatttggat
    17341 gtaaagtgtt ggcttatagt cgcagccgaa gtatagaggt aaactatgta ccgtttgatg
    17401 agttgctgca aaatagcgat atcgttacgc ttcatgtgcc gctcaatacg gatacgcact
    17461 atattatcag ccacgaacaa atacagagaa tgaagcaagg agcatttctt atcaatactg
    17521 ggcgcggtcc acttgtagat acctatgagt tggttaaagc attagaaaac gggaaactgg
    17581 gcggtgccgc attggatgta ttggaaggag aggaagagtt tttctactct gattgcaccc
    17641 aaaaaccaat tgataatcaa tttttactta aacttcaaag aatgcctaac gtgataatca
    17701 caccgcatac ggcctattat accgagcaag cgttgcgtga taccgttgaa aaaaccatta
    17761 aaaactgttt ggattttgaa aggagacagg agcatgaata gaataaaagt tgcaatactg
    17821 tttgggggtt gctcagagga gcatgacgta tcggtaaaat ctgcaataga gatagccgct
    17881 aacattaata aagaaaaata cgagccgtta tacattggaa ttacgaaatc tggtgtatgg
    17941 aaaatgtgcg aaaaaccttg cgcggaatgg gaaaacgaca attgctattc agctgtactc
    18001 tcgccggata aaaaaatgca cggattactt gttaaaaaga accatgaata tgaaatcaac
    18061 catgttgatg tagcattttc agctttgcat ggcaagtcag gtgaagatgg atccatacaa
    18121 ggtctgtttg aattgtccgg tatccctttt gtaggctgcg atattcaaag ctcagcaatt
    18181 tgtatggaca aatcgttgac atacatcgtt gcgaaaaatg ctgggatagc tactcccgcc
    18241 ttttgggtta ttaataaaga tgataggccg gtggcagcta cgtttaccta tcctgttttt
    18301 gttaagccgg cgcgttcagg ctcatccttc ggtgtgaaaa aagtcaatag cgcggacgaa
    18361 ttggactacg caattgaatc ggcaagacaa tatgacagca aaatcttaat tgagcaggct
    18421 gtttcgggct gtgaggtcgg ttgtgcggta ttgggaaaca gtgccgcgtt agctgttggc
    18481 gaggtggacc aaatcaggct gcagtacgga atctttcgta ttcatcagga agtcgagccg
    18541 gaaaaaggct ctgaaaacgc agttataacc gttcccgcag acctttcagc agaggagcga
    18601 ggacggatac aggaaacggc aaaaaaaata tataaagcgc tcggctgtag aggtctagcc
    18661 cgtgtggata tgtttttaca agataacggc cgcattgtac tgaacgaagt caatactctg
    18721 cccggtttca cgtcatacag tcgttatccc cgtatgatgg ccgctgcagg tattgcactt
    18781 cccgaactga ttgaccgctt gatcgtatta gcgttaaagg ggtgataagc atggaaatag
    18841 gatttacttt tttagatgaa atagtacacg gtgttcgttg ggacgctaaa tatgccactt
    18901 gggataattt caccggaaaa ccggttgacg gttatgaagt aaatcgcatt gtagggacat
    18961 acgagttggc tgaatcgctt ttgaaggcaa aagaactggc tgctacccaa gggtacggat
    19021 tgcttctatg ggacggttac cgtcctaatc gtgctgtaaa ctgttttatg caatgggctg
    19081 cacagccgga aaataacctg acaaaggaaa gttattatcc caatattgac cgaactgaga
    19141 tgatttcaaa aggatacgtg gcttcaaaat caagccatag ccgcggcagt gccattgatc
    19201 ttacgcttta tcgattagac acgggtgagc ttgtaccaat ggggagccga tttgatttta
    19261 tggatgaacg ctctcatcat gcggcaaatg gaatatcatg caatgaagcg caaaatcgca
    19321 gacgtttgcg ctccatcatg gaaaacagtg ggtttgaagc atatagcctc gaatggtggc
    19381 actatgtatt aagagacgaa ccatacccca atagctattt tgatttcccc gttaaataaa
    19441 cttttaaccg ttgcacggac aaactatata agctaactct ttcggcagga aacccgacgt
    19501 atgtaactgg ttcttaggga atttatatat agtagatagt attgaagagg ttctgttgca
    19561 aagttttaaa taaagaataa aatcccttac ggtatctatg atttaagctg ggattcccaa
    19621 taataccttg atttcagtac agaccgaaaa cccgaagaga gtgccttctt ttcgggtttt
    19681 cttatataat cctcgaatgg cttccatgcc tttaatcgtg gtagaggcag tgcgtaaact
    19741 tcgatagaat ttattgcgtc tctttactgg acgatggtct tgttcaatca aattattcag
    19801 gtatttaatg gtacgatgtt ctgtcccttg ataaaagccg tattctttta gtttcttaaa
    19861 ggcacttgta atagaggggg ctttatctgt gactacaacc ttcggttcat caaactgctt
    19921 cactaaccgc ttaagaaaag cataggctgc ttgtgtgtcc cgttttttac gtaaccaaat
    19981 atccaaggtt aaaccatctg catcgatggc tcgatacaaa taatgccatt ttcctttaat
    20041 tttgatgtac gtttcatcca ttttccatga ataaaaggat tttttatttt tctttttcca
    20101 aatttgatag agtagtttgc catattcttg cacccaacga taaatcgtcg tatgagaaac
    20161 gttaatgcca cgatcatata agatttcttg aacttcacga tagctaaggt tataacgaag
    20221 atagtagccc acggctacaa taatcacatc ctgctgaaat tgctttcctt taaaatgatt
    20281 catcgtcatt cctcctgcta tctttttcta ttattctacc ttatttgata gtagatttaa
    20341 aactttgcaa cagaaccatt gaagatgtaa ggcagagcga tattgcggtc attatctgcg
    20401 tgcgctgcgg caagatagcc tgataataag actgatcgca tagaggggtg gtatttcaca
    20461 ccgcccattg tcaacaggca gttcagcctc gttaaattca gcatgggtat cacttatgaa
    20521 aattcatcta cattggtgat aatagtaaat ccagtagggc gaaataattg actgtaattt
    20581 acggggcaaa acggcacaat ctcaaacgag attgtgccgt ttaaggggaa gattctagaa
    20641 atatttcata cttccaacta tatagttaag gaggagactg aaaatgaaga agttgttttt
    20701 tttattgtta ttgttattct taatatactt aggttatgac tacgttaatg aagcactgtt
    20761 ttctcaggaa aaagtcgaat ttcaaaatta tgatcaaaat cccaaagaac atttagaaaa
    20821 tagtgggact tctgaaaata cccaagagaa aacaattaca gaagaacagg tttatcaagg
    20881 aaatctgcta ttaatcaata gtaaatatcc tgttcgccaa gaaagtgtga agtcagatat
    20941 cgtgaattta tctaaacatg acgaattaat aaatggatac gggttgcttg atagtaatat
    21001 ttatatgtca aaagaaatag cacaaaaatt ttcagagatg gtcaatgatg ctgtaaaggg
    21061 tggcgttagt cattttatta ttaatagtgg ctatcgagac tttgatgagc aaagtgtgct
    21121 ttaccaagaa atgggggctg agtatgcctt accagcaggt tatagtgagc ataattcagg
    21181 tttatcacta gatgtaggat caagcttgac gaaaatggaa cgagcccctg aaggaaagtg
    21241 gatagaagaa aatgcttgga aatacgggtt cattttacgt tatccagagg acaaaacaga
    21301 gttaacagga attcaatatg aaccatggca tattcgctat gttggtttac cacatagtgc
    21361 gattatgaaa gaaaagaatt tcgttctcga ggaatatatg gattacctaa aagaagaaaa
    21421 aaccatttct gttagtgtaa atggggaaaa atatgagatc ttttattatc ctgttactaa
    21481 aaataccacc attcatgtgc cgactaatct tcgttatgag atatcaggaa acaatataga
    21541 cggtgtaatt gtgacagtgt ttcccggatc aacacatact aattcaagga ggtaaggatg
    21601 gcggaatgaa accaacgaaa ttaatgaaca gcattattgt actagcactt ttggggtaac
    21661 gttagctttt taatttaaaa cccacgttaa ctaggacatt gctatactaa tgatacaact
    21721 taaacaaaag aattagagga aattatattg ggaaaaatat tatctagagg attgctagct
    21781 ttatatttag tgacactaat ctggttagtg ttattcaaat tacaatacaa tattttatca
    21841 gtatttaatt atcatcaaag aagtcttaac ttgactccat ttactgctac tgggaatttc
    21901 agagagatga tagataatgt tataatcttt attccatttg gcttgctttt gaatgtcaat
    21961 tttaaagaaa tcggattttt acctaagttt gcttttgtac tggttttaag tcttactttt
    22021 gaaataattc aatttatctt cgctattgga gcgacagaca taacagatgt aattacaaat
    22081 actgttggag gctttcttgg actgaaatta tatggtttaa gcaataagca tatgaatcaa
    22141 aaaaaattag acagagttat tatttttgta ggtatacttt tgctcgtatt attgctcgtt
    22201 taccgtaccc atttaagaat aaattacgtg taagatgtct aaatcaagca atctgatctt
    22261 tcatacacat aaagatattg aatgaattgg attagatgga aaacgggatg tggggaaact
    22321 cgcccgtagg tgtgaagtga ggggaaaacc ggtgataaag taaaaagctt acctaacact
    22381 atagtaacaa agaaagccca attatcaatt ttagtgctga ggaattggtc tctttaataa
    22441 atttccttaa cgttgtaaat ccgcattttc ctgacggtac ccccaaacta agatttcata
    22501 gatagatttt ctgataactt taaaaaacac gaatagcgga aaggatgtct tcattcgcta
    22561 aagagtaata aactactttt ccatcttgac gtgattttgc cattccatgt ttttttaaaa
    22621 aacgtaaatg gtgtgacgtt gtagcgacac tagcagtaag tatttctgct aaatcacaga
    22681 cgcacatttc cttataggtt tctaaagcat agaaaatttt aattctagaa aaatcgctga
    22741 aacatttccc taacacaagt aagtttgaaa aatctttttg atccaattta ttttttattc
    22801 catttacttt ttctttatgt acgacagtca cttggcaaac ttttttcatt catctcacct
    22861 cacattcaaa cgattatttg aatgaagtat acctatttga tcactctttt gtcaatctac
    22921 cttaattcca atacactatt ataagcaatt tcatgtattg aagtaaactt acttgcaagt
    22981 gcgtttttga ttccaagtta aaaacatatt attattctac ataatttcct aatcaaataa
    23041 aactcctttg aaaattgttc taaaggagtt ttattatttt gtatttctac taaaaatagc
    23101 gtacaatgta attactaagt aattacgaaa tgtaaaataa tggaggaaat aatatgatta
    23161 caaaaacaag aaaacaagga aattctatta tgttaacggt ccctaaagaa ttcgatgtgc
    23221 ccaatggtgt tgaagtagaa gctaagcttg tagagaatgg tatcctttat gagtttgtag
    23281 agcctaaaaa agaatttttt gattttagtg aagatatttt ggctgatatt ctttcagaag
    23341 gttatagcaa acaagagatc ttaaaagaat ttagaaatag aaaaaatgcg ttaacttctg
    23401 catttaaatc tattgctgaa gatactgttg caaattctaa accgatgaca aaagaggagt
    23461 tggcagcaga aattggctta tgagattcta ccttctaaac acgtaataaa gtatctaaaa
    23521 aaattaaaag agaaaacatt aaaagaacaa tttttaacga taatttatga tgagatagca
    23581 gttcgtcctc attcgggaga acaaaaaacg ggtgatttat caggaatttg ggctattgga
    23641 ttcaagtatg caggtacgac atatcgcgtt gcatatgaaa ttaaagataa tgcagtgata
    23701 cctatcttac tatgtggaac gcatgaaaat ttttatgaac aattaaaaaa gattaggtaa
    23761 gaacccaatg tttcaacttg agaggataga cgacacttta aaagataatt tttaacagct
    23821 gagagttgta ataccctata attttaaacc actaacctat atatttatga aaaatagaaa
    23881 aaattaaaac gcattttaag cctctttcaa attaaaagct tcatccttat gcacaaagag
    23941 ggcttaaaat gcgttatttt atattgtttt ttagtaataa taaaaaaatc actctaattc
    24001 tcccataaat attatagatt cctaaagatt aaaatagatt attccctatt gtcttttaag
    24061 tagcggtaga gtgttgcctt gctaatacca gtcatttccg taatttcttt tacgctataa
    24121 acctgacttt tatacaattt tactgctcga tcaacatctt tctggttcac tcgtggacgg
    24181 ccacctttac gacctctcgc acgtgcactt ttcaaacctt ctttggtacg ttcaacaatt
    24241 aaatcacgtt cgaactgact aaatgcttgg aagacagtca tcattaagcg tccgtgaggc
    24301 gtgctggtat cgaagttttc tttcaagctc accagcttaa catggtgttc ttcaaaatag
    24361 gtaacaaggt caatcaaatc ctttgtacta cgacccaatc gagaaaaact ttctacaatt
    24421 accgtatctc ccggacgaat tttatctttt aaacgattta gttggggacg aaccgctttg
    24481 gttcccgtca ttttctcagt taggatttca ttacaatttt gttcattgag taagtctaat
    24541 tgacgattta gttcttgtga acgtgtactc actcgggcat aaccataaat gtatccactc
    24601 atgcttttct tcctttcgta ctttaattct ggcttgattg tatcataaaa gggagttata
    24661 gatacatagt taatgcaaca agttatgata caaaatatga cctcttttat ttaataaaag
    24721 aggtcatttc attttgtctc ataatcgatt gtttttgata cgagtgtgta tacgaaataa
    24781 acaaaaaaat cttaagtaaa tttctagata cctaatttaa tcctaactag tgtatcctaa
    24841 agttaataac gagtttatca caatgaaaat tataaaatgc tcccatatta gatataacat
    24901 gcaatatttg aattagaact acaaaattta ttcgttttat aaagtaaata atgttgagat
    24961 actaaggaat agaatattat aaggaattga gctgaatgta ttggataaaa aaagaataac
    25021 tttattagag atggactata aaaatgctcg taattttctt ctgaagtctg aaagctattt
    25081 gaatgctcag ctaccagaat atattagttt tgacgaaact ttaaaatctg ctaaaaaagt
    25141 tttaacttcg ccgtttgtat aattaagcga gacaaataaa aaagccattt atgttacact
    25201 caaattgtaa tacccgctaa agcatacaag gagagtgaac ataaatgact tatacccatc
    25261 ttacaccaaa cgagcttgta atgatagaag catattttca tcaagaaact ccggttgcta
    25321 tcgttgcgaa gcagcttaaa cgtggacgcc aaacaattta caatgtctat aactttctca
    25381 aatgtggtgg aacagcactt gaatactttg aacaatacaa agaaaataag cgacgttgtg
    25441 ggagaaccga aatcattttt cctgctgagg aaaaagaata cattgaaaaa agatcaactg
    25501 aaggttggac cccagacgtc attattggcc gtgcagagcg aaccttctct tgttcaataa
    25561 gtaccctcta tcgccggttt aagacgggag aattcaatgt tttacattta ccgatgcaag
    25621 gaaaacgaaa accaaatggt tataaggaaa aacgtggaaa acaggcattc aaaagaaata
    25681 tttctgaacg taaaaaagat tatgtcgttt tcgaagaaga atttggacat ttagagggtg
    25741 atacgattgt cggcatccac cataaaagtg ccgtcatcac actcgttgag cgactttcaa
    25801 aagccattat cgtcttgaaa ccagaaggcc gtaaggcagt tgatattgaa aattcgatta
    25861 atgaatggct tcaatccgta cccaaaaatc ttttcaaatc aattaccttt gattgtggaa
    25921 aagaattctc taattggaaa agtattagta atacgaatga tattgatatt tatttcgcag
    25981 acccaggaac gccttcccaa cggggattaa atgaacattc aaacggactc ctccgaaaag
    26041 atggactacc aaaagaaatg gacttcaacc aagtcaatca aggattcatc tcatccgttg
    26101 cgtccaaaag aaaccatatc cctagaaaat cactaaatta ccaaacacca ttagaagttt
    26161 ttttgagtta cgtaaatgga aagttttgtc tcgcttaatt tgacaaataa tacttcaaaa
    26221 aaaaaccaac cgaaagatat aaaagatatt gtagatacac gaatgtataa agaacgtgat
    26281 gacttaaact atacgcttat tatcaataaa gatggaaact attcatggcg tcctctcgtt
    26341 ctactacatc ctattctata tgtagatttg gttaattgtc tcactaaaga agaccattgg
    26401 gaggagttaa aaaagaggtt tagtgaattt aaaaaagata aaaatattaa ctgttattct
    26461 atacctgttg aagcttccaa aggttcaaaa aggacagatc ttggtgaaac aatactaaac
    26521 tggtgggaat attttgaaca aaaaagctta gctcagaata ttaaatacca atattgcatg
    26581 tttactgaca tcgctgattg ttatccatca atttatactc actctataac atgggccatg
    26641 tatggtaaag aaaaagttaa aaatgatgaa aataagtgtt cgggctcact tggcgataaa
    26701 atagataaaa aaatatctgg aatgcaacac aatcaaacaa atggtatccc tcagggttcc
    26761 gttcttatgg attttgtagc agagatcgtt ctagggtatg ttgatttgag attatcgaaa
    26821 gaattaaaaa aattagaaaa tttaaaagat tacaaagtac tcagatatag agatgattat
    26881 agaatatttt caaataatcg taatgatttg gaacaaatta tgaaagtgtt atcagaagtc
    26941 ttatatgatt taaattttaa gttaaattct agtaaaacaa aattatcaga tgatattatc
    27001 atagattcta tcaaaaaaga taagctctat tgggaagaaa ttaaggcaag tataagaatg
    27061 aatgccacaa acttagatgg tgatagagaa attcgttata gtataaattt acaaaaacat
    27121 ttattggaaa taaaaaagtt agcagataag catcctaatt caggccaatt gaaaaaagca
    27181 ctttctgagt ttaataaaga acgcattatt aaaatcactt caaagccgaa cgatctttta
    27241 ccacttattg gtatcctggt agatatcatg ataaataacc cgggttcttt gccgcagtgt
    27301 gtcttaatta tagggcagtt attaaatttc gaaaatgaga gtaaggctag agaaatagtt
    27361 gaaatgatta taaacaaata tgctttaaag ccaaatactg aatttatgat gatatggttt
    27421 caaagattga ccaccatttt tggagaaatg tttgatagtg ttttatcatc cgaatttgta
    27481 tctaaaatca aagatcctgt ctctaatcag atgttttctg tagactggct aaatgaagat
    27541 gctaagaaat ctttttatga agggaccatt aaagacgaag agaaatatat taaaatgagt
    27601 aagaaaatat atattactga atttgatgat tttaatgatt atccttttta agtgaaaatt
    27661 tagaatgaat ataaaaaaca ttgataaagt ccgtataatt gtgtaaaagt aaaaaggcca
    27721 tataacagtc cttttacggt acaatgtttt taacgacaaa aacataccca ggaggacttt
    27781 tacatgaccc aagtacattt tacactgaaa agcgaagaga ttcaaagcat tattgaatat
    27841 tctgtaaagg atgacgtttc taaaaatatt ttaacaacgg tatttaatca actaatggaa
    27901 aatcaacgaa cagaatatat tcaagcaaaa gaatatgaac gaacagaaaa ccgacaaagt
    27961 caacgaaatg gctattatga gcgcagcttt acgacacgtg taggcacgct agaattaaaa
    28021 gtacccagaa cacgtgatgg ccatttttca cccacagtgt ttgaacgtta tcaacgaaac
    28081 gaaaaagccc tcatggcttc aatgttggaa atgtatgtat caggcgtttc aactcgtaaa
    28141 gtatcaaaaa ttgtggaaga actttgtggt aaatccgtct ctaagtcctt cgtttctagc
    28201 ttaacagaac agctagaacc tatggttaac gagtggcaga atcgtttatt atcagaaaaa
    28261 aattatcctt acttaatgac cgatgtactc tatataaaag tacgagaaga aaatcgagta
    28321 ctctcaaaaa gctgtcatat agcgattgga ataaccaaag atggcgaccg tgaaattatc
    28381 ggcttcatga ttcaaagtgg cgaaagcgaa gagacctgga caacattttt tgaataccta
    28441 aaagaacgcg gtttacaagg tacggaactc gttatttctg atgcgcacaa aggattagtc
    28501 tctgccatta gaaaatcctt caccaacgta agttggcaaa gatgccaagt tcacttccta
    28561 agaaatatct ttaccaccat tcctaaaaaa aattcaaaat ctttcagaga agctgttaaa
    28621 ggaattttta agttcacaga tattaactta gcgcgtgagg ctaaaaatcg attgattcat
    28681 gattatatcg atcaaccaaa atattcaaaa gcttgcgcat cattggatga tggattcgaa
    28741 gacgcctttc aatataccgt acaaggaaat tcccacaatc gactaaagag taccaatcta
    28801 attgaacgac tgaatcaaga agtacgcaga agagaaaaga ttattcgcat cttccccaat
    28861 caaacatcag ccaatcgctt aattggagcc gttcttatgg acctacatga tgaatggatt
    28921 tattcttcaa gaaaatacat caattttgat aagtagaaat ggtaaaaaca ttgtatagca
    28981 ttttacacag gagtctggac ttgactaaaa cattacaatc taattttttt aaaaaaatgt
    29041 tatatcggaa gtaatctctt gatttctata ctataagata agaaaaccac tatttaacaa
    29101 ggttattcga accttatttt aagttactta ttatttaatg tatcgaaaaa ggtgaaatag
    29161 gtttgttata ataagaatta agtaagacat gaattgtcta agcaaatgta gcttatccat
    29221 ttcattaaaa tacatatggt gaaaaaacaa gttcaaatag taactaattt tttaaaaaac
    29281 tgatttataa aaaatacaac acgaatgagg aaaataacca atgacagaac aaatcgaaaa
    29341 aaattcaaaa agcttatatc aggcactgtg gaattccgca gatatcctgc gttcaaaaat
    29401 ggacgctaat gaatacaaga gctatttact aggcttggtc ttttataaat acttatccga
    29461 caacatgctg cggtatgtct ccgttctatt ggaggaagaa acggacgacc taaataaagc
    29521 acaagacctt tacgttgaag catttaaaga tgcagatata aaggatgatc tcttgtatga
    29581 actaaaagat gagttttcat ataccatcgc acccgcattg acctttaccg cgcaagtggc
    29641 agccattcat gatggatctt ttcaattaga agacctggta caaggtttcc gtgacattga
    29701 acaatccagc gaaaactttg agaacttatt tgaagacatt gatctgtatt ctaaaaaact
    29761 ggggtcaacc ccacaaaaac aaaataaaac catcgcagat gttatgaaag aattagaagg
    29821 gttaaacatg gcggggcatg ctggcgatgt cttaggcgat gcctatgagt acttaattgg
    29881 ccaattcgca tctgaatccg gtaaaaaagc cggtgaattc tataccccac aaccggtcgc
    29941 aaaattgatg acacaaattg ttttacaagg aaaagaagat aaaaaaggct tttctgttta
    30001 cgacgcgacc atgggttcgg gctcgttact tttgaacgct aaaaaatatt cccatcaacc
    30061 gggaaccatt tcttatttcg gacaagagtt gaatacgtct acctataatt tggcgcgtat
    30121 gaacatgatt ttgcatgggg ttcccattgc caaccaacac ttgcataatg cggatacctt
    30181 ggatcaagac tggccaacag aagagccaac gaacttcgat ggggtgctca tgaacccacc
    30241 gtattctgca aaatggtcgg ctgataaagg cttcttagat gacccacgct tctctgccta
    30301 tggcgtatta gcccctaaat caaaagcgga ctttgctttc ttattacatg gctactatca
    30361 tttgaaagat acgggcgtca tggccattgt tttgccacat ggggtgctct ttagaggggg
    30421 cgcagaaggg aagatacgca aagccttgtt agaaaatggt gccattgaca ccgtcattgg
    30481 cttacctgct aacatcttct ttaatacgtc cattccaacg accgtaatta tcttgaagaa
    30541 agaccgtgcg aaaaaagatg tgctctttat tgatgcgtca caagattttg aaaaaataaa
    30601 aacgcaaaat acgctacgag attaccatat tgacgctatt ttagaggcct ataaaacccg
    30661 tacaattaaa gacaagtatg cttatgtcgc agaatttgat gaaattgtgg agaatgatta
    30721 caacttaaac attccccgtt acgtggatac ctttgaagaa gaagaagggt tctgttgcaa
    30781 agttttaaat aaagaataaa atcccttacg gtatctatga tttaagctgg gattcccaat
    30841 aataccttga tttcagtaca gaccgaaaac ccgaagagag tgccttcttt tcgggttttc
    30901 ttatataatc ctcgaatggc ttccatgcct ttaatcgtgg tagaggcagt gcgtaaactt
    30961 cgatagaatt tattgcgtct ctttactgga cgatggtctt gttcaatcaa attattcagg
    31021 tatttaatgg tacgatgttc tgtcccttga taaaagccgt attcttttag tttcttaaag
    31081 gcacttgtaa tagagggggc tttatctgtg actacaacct tcggttcatc aaactgcttc
    31141 actaaccgct taagaaaagc ataggctgct tgtgtgtccc gttttttacg taaccaaata
    31201 tccaaggtta aaccatctgc atcgatggct cgatacaaat aatgccattt tcctttaatt
    31261 ttgatgtacg tttcatccat tttccatgaa taaaaggatt ttttattttt ctttttccaa
    31321 atttgataga gtagtttgcc atattcttgc acccaacgat aaatcgtcgt atgagaaacg
    31381 ttaatgccac gatcatataa gatttcttga acttcacgat agctaaggtt ataacgaaga
    31441 tagtagccca cggctacaat aatcacatcc tgctgaaatt gctttccttt aaaatgattc
    31501 atcgtcattc ctcctgctat ctttttctat tattctacct tatttgatag tagatttaaa
    31561 actttgcaac agaaccataa aagctacgaa agccatatgc atttcgtttt aacactttga
    31621 tatggttgtt cagacattca agtgggccat ttgaataact ttgttgtaaa gcatttttga
    31681 tttgtggcag aaatttctgg aacgttctca aggtcgtctg atagccttcg ggaagcatga
    31741 tattattggt aagtagttct tcaaacgata cgtagtctcg ttcctttaca gcgtaaagaa
    31801 agtcttgata taactgatag cctacacgca aagcagggct ccctttcagt aagcgatcca
    31861 caatatcggt ctctgttaaa tgagctttga agccaggtcg ccaaaggcgt cgagtataat
    31921 caagcttgcg ttcatctttt tgaagaagtt tccagtatct ttttaattgc ttacctaatt
    31981 gatagtgttt ttgttctttg ctttttaata gttggttcgt ttctttgatt cgatgattgc
    32041 gaaaggtacg accaatatgt tggacgatgt gaaaccggtc aataatcagc tgtgcttttg
    32101 gaaacagctt tttaacgagc gatacataag gagcgtacat atcaatcacg atccattcga
    32161 ccgcttcacg aatttctcgt gaaaaatgac taaaataacg ttttaaaaaa ggcagttgtc
    32221 ggttctcgac aatgtccaat aagcgctgtg tttgtccatc catcatgatg aaactcatag
    32281 cacctgaaac accccgaact gatttgaatt catcaaaaca aagtacctta ggtaacggtg
    32341 tccgaaaagg attcaacgga cgataaaatc gcttcataat acggtaaaca gaagagaccg
    32401 atagattttt ctgagcggcg atctctgtca ttgaggtatt ttttttcaga cgagtcacga
    32461 cagaccagcg gactttctca ctgatgaaac aatgtttttt cgcaacagaa gtatctgcga
    32521 caaaggtccg ctgacaagct ttgcatttga agcgttgctt tttcaattcg aggtaggtac
    32581 ggtattcaga aacatcgttc attaacaacc ggacggttgt tgtaccccaa cgcacaatat
    32641 ctgaagcaat ctggtgttta cagtggatgc attcttgggc tgtataaatc aagtttccac
    32701 gataaatatg acagatttgc cctttgtatt tttcttttgt gagacaattt tcgttaaaag
    32761 taactgataa gtctagaata tctaatgttt ctttgataag gtgagtgtaa gacatcttga
    32821 ttcctccttt tgggttggtt cgccaaatta attctaaagg atttcaaggt gtcttttcta
    32881 tatgttttgg aaaataaaaa agatgctggt gtcatccacc aacatcaaaa agtatagagc
    32941 cgataataaa agcagcatga tcaactattt gtcattgacc atgctgtctt tttttattct
    33001 atacacggtt tgtctcgtaa cattgtagtc tttagcaatc ttagcaatcg caacaccatt
    33061 tttaagatct tcaacgatgc ttttgtaaac aaggcgacgt tggggatctt ttgcgtctgc
    33121 actgtataat ttgggccgcc ctttgtagac gccgtttgct tttgcgatct taattccttg
    33181 tgcctggcga cgtttcgatt cagtccgttc ttgttcagcg atcatggcca aaatttggat
    33241 gatcagatcc ttaatgaatt tatccaggag aggattgcca attgcttcag ccatgatcgg
    33301 taaactagta atgatcagct tcacattttt cttcttcaag taattgactg aagtgatgat
    33361 ctcgtcataa tttcttccaa gtcgatcaat agcttccaca ataaaaatat cttgatctcg
    33421 gacgtaatct aatgcttctt ggaaaacagg tcgatgagta atcgttgcgc cagattgttt
    33481 ctcgatgaaa attctctctg caccgaattt tttcatttct tcaatctggc gttgttcatt
    33541 ttgatcgatc gatgagacac gtatgtatgc aactctcaaa acttttacct actttctgca
    33601 actatttaaa atacacccta atcatacacg aggaagccat atttttcaat gttataccag
    33661 tgtctattta gggtaaacct tatatagaca aaaactaatg atggaggaaa tagtatgtgt
    33721 cacttttctt tttaaatggc aatatttttt gtaaataaat gtcaatcaag aaaatttaaa
    33781 cgattatgac attaaaaata tattttatga attttctagt atataacttg atttatctgt
    33841 taagatttat taagaaaacg ttttcttatt tttgatttcg aggtgataga caatgaaaaa
    33901 taagtttatt ttatctttag gtattttaac tattggaatt agtgtaactg gaactacaat
    33961 tcctacattt gctgatagta caaatgaacc aactactgta gtagataata accaagaatt
    34021 aactccttta gataggaacg gaatagccat tggtaaccca actaacgact taactgttac
    34081 tgaaaattat ttaatagttt ctccattact tgctcgagca gcttctaaaa cgatacgagt
    34141 gacaggaacg atgatttttg ataaagttgg ttggccttct agacctcctc aatcacggaa
    34201 ttggaaagaa aaaagaaatg gttattggta ctatggaaaa ttgtatttac aaagttataa
    34261 atcagctgga aacaattgga ttgcgactta ttcaggaacc ttaactagaa agtagggatt
    34321 ttttatgcca gaatttgtga acacaccaaa tttttatcaa gatagcgata ttctaagtaa
    34381 aattaattta ccgaaagaag aatcagcttt acaagttcag cgaactttac aggagacaca
    34441 aaaaattcaa aaatcaattt ctaatctaga agattctgaa gaaaaaagaa aaaaaagaga
    34501 ccaaaaaaca tatcaaaaag aaaaataatg attttaaaaa aagagtgtct agtcgacatt
    34561 ctttttttct aattgaaagt gttcataaaa tcacccattt ctggacactt tctttttttg
    34621 ctttattttt caaaaaaaca attcatttca tgttcataaa cccataacaa tatctatgtt
    34681 cagttaaact atatggataa agttatgtta caataaaatt aatgaaggag tgattttttt
    34741 gaaaatagga tacgcccggg tatctactgg tttacaaaat ttggatttac aagaagacag
    34801 cctaaataaa tttggttgtg aaaaaatttt tactgatcat atgagtgggg caaaaagtaa
    34861 tcgaccagga ttagaaatgg ccattgattt tgttcgctct ggcgatacac ttgtcgtttg
    34921 gcgcttagat cgtttaggta gaaatatgga agatttgatt tcaatcgtca atcgactgaa
    34981 tgagcgtggt gtgagttttc atagtattca agaaaatatt acgatggaca aatcaagttc
    35041 tacaggacag ctcatgtttc atttgtttgc ggcatttgca gaatttgagc gtaatttgat
    35101 cctggaacga tccgcagcag gacgagcagc tgctcgtgca agaggacggt ttggtggtcg
    35161 tcctgaaaaa ttgtctgaac aagatttgga attactgaag actttagtgg atagcggtac
    35221 acctattaag actattgcgg aacggtggaa cgtctcaaga accaccattt atcgttattt
    35281 ggcaaaaatg gaggagaaaa atggaaagac aaattctcat tagtttttgt catttaatgc
    35341 tgaaaatttt tgccatttat ctagaaaagt gacaatagta tgagaatttt ttgtaagtgt
    35401 ctactgataa cttattctca aatatttagc tatttcttct ttacaacatc gaacatatgt
    35461 ttgtataatg tggaagaatg gagtgttatt tatgatggat tattcaaaag agccagtaaa
    35521 tgattacttt ttaatcgata tgaaaagctt ttacgcaagt gtcgaatgta tagaaagaaa
    35581 tttagatcca ttaacaacag aacttgttgt tatgagtcga tctgataata ctggttcagg
    35641 attgatatta gcttcttctc ctgaagcaaa aaagcggtat ggtattacaa atgtgagtag
    35701 accacgtgac ttaccacaac catttcctaa aacactacac gttgttccac cacgtatgaa
    35761 cctatatatc aagcgaaata tgcaggtaaa taatattttc agaagatatg tggctgatga
    35821 agatctactg atttactcga tcgatgaatc gattttaaaa gtgacaaaat cactgaatct
    35881 ttttacgact gaagaaacac gaagtcagcg aaggaagaag ctcgctcaaa tgatccaaga
    35941 acgtattaaa gaagagttag gtttgattgc tacggtaggc gtcggcgata atcccctttt
    36001 ggctaaatta gccttagaca atgaagcaaa gcataatgaa ggatttattg cggaatggac
    36061 gtacgaaaac gttcctgaga aagtatggaa tattcccgaa atgacggact tttggggaat
    36121 tggttcgcga atgaaaaaaa ggctcaacca aatgggaatt ttgagcatta gagaccttgc
    36181 taactggaat ccttatacga ttaagaatag attaggtgtg attggattac agctgtactt
    36241 ccatgctaat gggatcgatc gaacagatat agcaatccca ccagaaccga caaaggaaaa
    36301 atcatatgga aattcacaag tgttaccacg agattatact agaagaaatg aaatcgagct
    36361 ggtggtaaaa gaaatggcgg aacaagtagc gatacgcatt aggcagcata actgtaaaac
    36421 aggttgtgtc catttacaca ttggcacgtc gatcttagaa acgagaccag ggttttcaca
    36481 ccagatgaag atccctatca cagataatac aaaggaattg cagaattatt gtcttttctt
    36541 gtttgataag tattatgaag gacaagaagt aaggcatgtt ggaataacct atagcaagct
    36601 tgtgtacacc gattcgcttc agctggattt atttagtgat ccacaaaagc aaattgacga
    36661 agaaaattta gataaaatta ttgacaagat tcggcaaaaa tatggtttta cgtcgattgt
    36721 acatgcttct tcaatgttag aaggcgctag aagcattact agaagcacac ttgttggtgg
    36781 tcatgcgggc ggaaatgggg gaattaaaaa tgattgatta caatgatcgt ggacgtttaa
    36841 agtgggcagg gttttattta tctgatcata ctgaagaaat tgatgccgac aatgaacaac
    36901 gaaccagtca aaatttagca aaagaacaaa tgacgactga agagattgcg gaagtattga
    36961 acgctgcagt cataaaaaat agatcagtat ctattcaaaa agaagaacga aacgctgaag
    37021 gatactatcc agaagatatc attggcaaga tcttaggtag tgatgagctg gggatctacg
    37081 ttggaaaaga caaaattcac tacgacgaaa tacgtcatat cgaattttac caggataata
    37141 aatggagtcg attagaatga acattatcca gcaatatgag ctaaagtata taacctttga
    37201 tcagctatca gaagagattt ggggttatgg ccaacgtttg ataaatgagg ttggtgttga
    37261 gcgcttctct ttctatgtag aagctgcagc aggttatcat aattttaggt tttatatctt
    37321 cccgttatat atataaggta ttttacggat tctatagagt tatctctatg aatccttttt
    37381 tgtttttaca aataggagta gatactagaa taatgcgtgt gttaaactat tattgcaaac
    37441 gcaataataa aagaaagtag gcttacgcac catgtctatc aatacatttg tttactcgca
    37501 cccgatcaat gtttacatta tcaagaattt aggaatcact gtagaacaat tttgtgagtt
    37561 atatgcctac ccacaaggaa cggttgcaag ctggataacc cgacaacgta gaataaaatc
    37621 attacctgct tcattcgttt atgatttaag cctggcctct agtttaaaca tgtctgatgt
    37681 ttatgaaaag ctcctgtctt tagaaaaaga atatgattcc ttcaagatta aacatgataa
    37741 aaaaataaaa aaacatatat aatatcaatc acaattgtat aatattacga tatcttaata
    37801 tcatgatatc gtaatattgt ttttttctaa gaaaatgcac tataagaagg gaattattag
    37861 taacaatata gacagtttag taatgtttaa attattctag ttgctgctcg caaaacatat
    37921 ttcttatcat taataaaaaa ttttaaagta ataaaaagga taaagtccgt ataattgtgt
    37981 aaaagtaaaa aggccatata acagtccttt tacggtacaa tgtttttaac gacaaaaaca
    38041 tacccaggag gacttttaca tgacccaagt acattttaca ctgaaaagcg aagagattca
    38101 aagcattatt gaatattctg taaaggatga cgtttctaaa aatattttaa caacggtatt
    38161 taatcaacta atggaaaatc aacgaacaga atatattcaa gcaaaagaat atgaacgaac
    38221 agaaaaccga caaagtcaac gaaatggcta ttatgagcgc agctttacga cacgtgtagg
    38281 cacgctagaa ttaaaagtac ccagaacacg tgatggccat ttttcaccca cagtgtttga
    38341 acgttatcaa cgaaacgaaa aagccctcat ggcttcaatg ttggaaatgt atgtatcagg
    38401 cgtttcaact cgtaaagtat caaaaattgt ggaagaactt tgtggtaaat ccgtctctaa
    38461 gtccttcgtt tctagcttaa cagaacagct agaacctatg gttaacgagt ggcagaatcg
    38521 tttattatca gaaaaaaatt atccttactt aatgaccgat gtactctata taaaagtacg
    38581 agaagaaaat cgagtactct caaaaagctg tcatatagcg attggaataa ccaaagatgg
    38641 cgaccgtgaa attatcggct tcatgattca aagtggcgaa agcgaagaga cctggacaac
    38701 attttttgaa tacctaaaag aacgcggttt acaaggtacg gaactcgtta tttctgatgc
    38761 gcacaaagga ttagtctctg ccattagaaa atccttcacc aacgtaagtt ggcaaagatg
    38821 ccaagttcac ttcctaagaa atatctttac caccattcct aaaaaaaatt caaaatcttt
    38881 cagagaagct gttaaaggaa tttttaagtt cacagatatt aacttagcgc gtgaggctaa
    38941 aaatcgattg attcatgatt atatcgatca accaaaatat tcaaaagctt gcgcatcatt
    39001 ggatgatgga ttcgaagacg cctttcaata taccgtacaa ggaaattccc acaatcgact
    39061 aaagagtacc aatctaattg aacgactgaa tcaagaagta cgcagaagag aaaagattat
    39121 tcgcatcttc cccaatcaaa catcagccaa tcgcttaatt ggagccgttc ttatggacct
    39181 acatgatgaa tggatttatt cttcaagaaa atacatcaat tttgataagt agaaatggta
    39241 aaaacattgt atagcatttt acacaggagt ctggacttga ctataaaaag tgattatttt
    39301 aatttcgaat aacatatgaa taatctttat atccgaaccg atatatatct ttaaaacaaa
    39361 ataatcacac aatattacaa tataatgcat atacgatatt gcaatatcac aatattatga
    39421 tataattata ttataatata agatgaatgg gggatatttt aatggcaaga atattgtcag
    39481 tagccaatca aaaaggtgga gtttctaaaa ctacgactag cgttaattta gcagcatgtt
    39541 tgaaatttgt ttacggtaaa aatgtacttt tagtggacat tgatcctcag ggaaatgcta
    39601 cagataatgt aggtttcgat atagatggaa caaaccaacc tacaatttat gaagtattaa
    39661 aaggggaggc tgacattaca gatgctattc tggactataa aggaattgat gttttgccag
    39721 ccgacatagc cctttcttct gcagagaggg aatttactca agtaggaagt gaacacaggc
    39781 ttaaaagagt acttcaacca atcaaggaca actatgatta tattataatt gattgtccac
    39841 caagtttagg aatgcttaca gtcaacgcat ttactgtttc tgatgaaatt atcattccag
    39901 ttgaagctgc gtatttctca ttaaaaggac taataaagtt aagtgaaact attgaaacgg
    39961 taaaagaata tacgaacgac aagcttgaag tacgaggagt tctatttact aagtataata
    40021 agcgttataa catttctaaa gaaatgacgt ctgcagcaac cgaaatttct agagtcattg
    40081 gtgcaaaaat tttcaaaact tatattcgta ggacaataac cgttgacgaa gcgcaagctg
    40141 ctggatcaga tctaatcaat tttaataaac cctcaacagc tgaagatgac tataaagcat
    40201 ttacagaaga atatttaaaa gaagttggtg attttgatgg cagaagataa tcgcagtcaa
    40261 gctgcagtaa gtagattact aggaaataaa aataaaaaga attttaaatc aaaagaagta
    40321 gaagaaatcg aattaaccaa gaaaaatata agtaaagtca taaaagatca aggaagtagt
    40381 gtaagaacag cagatagcat tcgtataaat ccaattctaa tgtcagcact caaatattgg
    40441 acgactattg ctgaatcaga caaaagtaaa ccagacgtta tagaagatgc gctattaaag
    40501 tccatacctg aagaatactt gattgaagga tataaactag caaagaaaca aaataaaatt
    40561 taatttacat tcaatatcac gatatcataa tatcgtgata ttttttttat aaaaatcagt
    40621 agtatcaaag ctgataagtc gcttatcttc atattgtaat attacgatat cgtgatataa
    40681 tattattgta atatcgtgat atagttacta tgagcttaaa ccttgaaata gagcggtttg
    40741 ctttaattta ttttttaagg taaactaaaa aaagataaaa aaagactact gctttaacaa
    40801 agtttggcga cttatcagca gtagaaaaat atatagtgga tagatatatt tgtttaattc
    40861 attgtaacat agttttgaac aaaacgctat cctacagaaa gaggattggc t
//
