LOCUS       NZ_CP023528             9195 bp    DNA     circular CON 25-JUL-2023
DEFINITION  Citrobacter koseri strain FDAARGOS_393 plasmid unnamed, complete
            sequence.
ACCESSION   NZ_CP023528
VERSION     NZ_CP023528.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN07312437
            Assembly: GCF_002393245.1
KEYWORDS    RefSeq.
SOURCE      Citrobacter koseri
  ORGANISM  Citrobacter koseri
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Citrobacter.
REFERENCE   1  (bases 1 to 9195)
  AUTHORS   Minogue,T., Wolcott,M., Wasieloski,L., Aguilar,W., Moore,D.,
            Tallon,L., Sadzewicz,L., Ott,S., Zhao,X., Nagaraj,S., Vavikolanu,K.,
            Aluvathingal,J., Nadendla,S. and Sichtig,H.
  TITLE     FDA dAtabase for Regulatory Grade micrObial Sequences (FDA-ARGOS):
            Supporting development and validation of Infectious Disease Dx tests
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9195)
  AUTHORS   Minogue,T., Wolcott,M., Wasieloski,L., Aguilar,W., Moore,D.,
            Tallon,L., Sadzewicz,L., Ott,S., Zhao,X., Nagaraj,S., Vavikolanu,K.,
            Aluvathingal,J., Nadendla,S. and Sichtig,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-SEP-2017) Center for Devices and Radiological Health,
            US Food and Drug Administration, 10903 New Hampshire Avenue, Silver
            Spring, MD 20993-0002, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SMRT v. 2.3.0, HGAP v. 3
            Genome Coverage                   :: 985.14x
            Sequencing Technology             :: PacBio; Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 07/25/2023 03:32:36
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,638
            CDSs (total)                      :: 4,523
            Genes (coding)                    :: 4,472
            CDSs (with protein)               :: 4,472
            Genes (RNA)                       :: 115
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 85
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 51
            CDSs (without protein)            :: 51
            Pseudo Genes (ambiguous residues) :: 0 of 51
            Pseudo Genes (frameshifted)       :: 22 of 51
            Pseudo Genes (incomplete)         :: 30 of 51
            Pseudo Genes (internal stop)      :: 13 of 51
            Pseudo Genes (multiple problems)  :: 11 of 51
            Pseudo Genes (short protein)      :: 1 of 51
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP023528.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..9195
                     /organism="Citrobacter koseri"
                     /mol_type="genomic DNA"
                     /strain="FDAARGOS_393"
                     /serovar="FDA:FDAARGOS_393"
                     /isolation_source="UCC strain"
                     /host="Environment"
                     /culture_collection="FDA:FDAARGOS_393"
                     /db_xref="taxon:545"
                     /plasmid="unnamed"
                     /collection_date="2005"
                     /collected_by="USAMRIID"
     gene            complement(269..418)
                     /locus_tag="CO700_RS23835"
                     /old_locus_tag="CO700_23835"
     CDS             complement(269..418)
                     /locus_tag="CO700_RS23835"
                     /old_locus_tag="CO700_23835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891188.1"
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="WP_004152552.1"
                     /translation="MKKVKVVFLFILIFSGFLLVACQANYIRDVQGGTVAPSSSSELTG
                     IAVQ"
                     /name="colicin release lysis protein"
     gene            complement(503..760)
                     /locus_tag="CO700_RS23840"
                     /old_locus_tag="CO700_23840"
     CDS             complement(503..760)
                     /locus_tag="CO700_RS23840"
                     /old_locus_tag="CO700_23840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cloacin immunity family protein"
                     /protein_id="WP_004152553.1"
                     /translation="MGLKLHIHWFDKKTEEFKGGEYSKDFGDDGSVIESLGMPLKDNIN
                     NGWFDVEKSWVSILQPHFKNVIDISKFDYFVSFVYRDGNW"
                     /name="cloacin immunity family protein"
     gene            complement(770..2455)
                     /locus_tag="CO700_RS23845"
                     /old_locus_tag="CO700_23845"
     CDS             complement(770..2455)
                     /locus_tag="CO700_RS23845"
                     /old_locus_tag="CO700_23845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin-like bacteriocin tRNase domain-containing
                     protein"
                     /protein_id="WP_004178188.1"
                     /translation="MSGGDGRGPGNSGLGHNGGQASGNVNGTSGKGGPSSGGGTDPNSG
                     PGWGTTHTPNGDIHNYNPGEFGNGGSKPGGNGGNSGNHSGSSGGGQSSATAMAFGLPAL
                     ATPGAEGLALSVSGDALSAAVADVLAALKGPFKFGLWGIAIYGVLPSEIAKDDPKMMSK
                     IVTSLPADTVTETPVSSLPLDQATVSVTKRVADIVKDERQHIAVVTGRPMSVPVVDAKP
                     TKRPGVFSVSIPGLPSLQVSVPKGVPAAKAPPKGIIAEKGDSRPAGFTAGGNSREAVIR
                     FPKESGQKPVYVSVTDVLTPAQVKQRLEEEKRRQQAWDAAHPEEGLKREYDKAKAELDA
                     EDKNIATLNSRIASTEKAIPGARAAVQEADKKVKEAEANKDDFVTYNPPHEYGSGWQDQ
                     VRYLDKDIQNQNEKLKAAQTSLNEMNESLSRDKAALSGAMESRKQKEKKAKDAENKLNE
                     EKKKPRKGTKDYGHDYFPDPKTEDIKGLGELKEGKPKTPKQGGGGKRARWYGDKKRKIY
                     EWDSQHGELEGYRASDGEHLGAFDPKTGKQVKGPDPKRNIKKYL"
                     /name="colicin-like bacteriocin tRNase domain-containing
                     protein"
     gene            2857..3276
                     /locus_tag="CO700_RS23855"
                     /old_locus_tag="CO700_23855"
     CDS             2857..3276
                     /locus_tag="CO700_RS23855"
                     /old_locus_tag="CO700_23855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Exc2 family lipoprotein"
                     /protein_id="WP_001254601.1"
                     /translation="MRRSGSKLCLIAMITATATLTACAPKGSVEQHTRHYVYASDDGFD
                     PNFSTQKADTTRMMVPFFRQFWDMGAKDKATGKSRSDVQQRIQQFHSQEFLNSLQGTTQ
                     FAGTDYRSKDLTPKKSRLLADTISAVYLDGYEGRQ"
                     /name="Exc2 family lipoprotein"
     gene            3582..3845
                     /locus_tag="CO700_RS23860"
                     /old_locus_tag="CO700_23860"
     CDS             3582..3845
                     /locus_tag="CO700_RS23860"
                     /old_locus_tag="CO700_23860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000072676.1"
                     /translation="MSNTTHYENANFLRELAESLPRILPEGGPDKAALLQRLANEELAQ
                     AEYEDQVRAKVTAARADTRPGMTTEQLRQRLHGRYQELRDAV"
                     /name="hypothetical protein"
     gene            3835..4134
                     /locus_tag="CO700_RS23865"
                     /old_locus_tag="CO700_23865"
     CDS             3835..4134
                     /locus_tag="CO700_RS23865"
                     /old_locus_tag="CO700_23865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146176.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_001146176.1"
                     /translation="MPYDVEWKQGAIEDVTTLFDYIAENSSLWDAQNVTDRVLAAADKL
                     ADFPRLYEVDSRYGEDVRRISLMGQHVLYDVDDQTRKVRVLAVVGQRQNPHIVL"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(4196..4573)
                     /locus_tag="CO700_RS23870"
                     /old_locus_tag="CO700_23870"
     CDS             complement(4196..4573)
                     /locus_tag="CO700_RS23870"
                     /old_locus_tag="CO700_23870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000312627.1"
                     /translation="MAWVTVRQATELTGKARSSLYRDMAKGRVSYRTEADGGRVVDTSE
                     LIRVYGELRQDETHERDELRLSGETEKMASDALIAEIKALREEVAGLRQEMQSMRLLEH
                     KPETAETPAGTPRRWWPWGKR"
                     /name="hypothetical protein"
     gene            4642..4821
                     /locus_tag="CO700_RS23875"
                     /old_locus_tag="CO700_23875"
     CDS             4642..4821
                     /locus_tag="CO700_RS23875"
                     /old_locus_tag="CO700_23875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_000165971.1"
                     /translation="MTKQEKTALNMAKFIKEQSLLLLDKLNELDMDTPADMCERLHEDA
                     ETLWQVMRDKLGEE"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            complement(4849..5379)
                     /locus_tag="CO700_RS23880"
                     /old_locus_tag="CO700_23880"
     CDS             complement(4849..5379)
                     /locus_tag="CO700_RS23880"
                     /old_locus_tag="CO700_23880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008321413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004153058.1"
                     /translation="MALYMVFIEDAEDRNGERCIMPTSEHLEDMVVLAWQTGAYVFCFV
                     DRAQHLAMMKSIGMYDERLNSDEKATYFFTGKNPQWERNKPTGMKLCDYLYRKVERFAI
                     ENGVQVVDAGKCSPEQINAMIDVVSERHGESAVNEKLKAELMREYNSRYFNVPVPELPE
                     DKPARRWWPFGKK"
                     /name="hypothetical protein"
     gene            complement(5386..6117)
                     /locus_tag="CO700_RS23885"
                     /old_locus_tag="CO700_23885"
     CDS             complement(5386..6117)
                     /locus_tag="CO700_RS23885"
                     /old_locus_tag="CO700_23885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family replication-relaxation protein"
                     /protein_id="WP_004152551.1"
                     /translation="MALELYNVSHAKRQARNAEKTRLTLRWLREELCSTAELVARRLGI
                     AAVQPVYRFLDSLVAKGLLVRTKYPVDGRQVSVWGLTPHGVAFSFDEDEPLADVIPFQP
                     SRVSAAHLPHRLAVQSLRLDMEARGATGWRILHRLSLKGMKVPDALAELDGKTVAFEVE
                     RTVKSRRRYQEVVSGYLFNRKANGIDEIWYICPDRATQVRVQRAILSVDEIVNPQTGEA
                     RKTAELDRERLFACFKFMTTE"
                     /name="MobC family replication-relaxation protein"
     gene            complement(6117..8081)
                     /locus_tag="CO700_RS23890"
                     /old_locus_tag="CO700_23890"
     CDS             complement(6117..8081)
                     /locus_tag="CO700_RS23890"
                     /old_locus_tag="CO700_23890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004178196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="WP_004178196.1"
                     /translation="MFNTDSLAWKWHIPELARQIYPWVSWLYQEYYGLAGAFLVIGLFF
                     GLAELWAGRMRFVGLSHKERREYADRYKRDNKRPAPFSVLASLDSPGRMVRARRHVWNY
                     AYWLTGAAGLALLGGLVVAVFIESWGETVLRPDLYANADYYLLQPANLFGIAWCAGGLA
                     VGIVLARLLAFLLLDGHFAAADEAVNAKLNQESRRSSQRTGEMTDVRHLHFGEPVPVNA
                     LADFSSEQARQEQAVFLGKDEQGKPVLVPRDTWRKTNIQILGLPGSGKSVMATNALIRC
                     VRDFGDAVVYFDPKGDAWAPHVFRAHCPDFTLLDLRPGKPAQLNLFRDLDQYALKNLLI
                     AGLNLGETGDVADHYRISEQKAAKLIAEQFPQGANIQQVLAAAYALPEALKKDVKGLIT
                     RLENVADLSVLQTDSGIDVAGIINGGGCLYVIGSMDDEAVIRVQKMLFARCAQIIIARD
                     EFREWPHVSVMLDEIKYLLSKYVLNALGTLRSRDCNLLLAHQSLGDFGQCGQDLPAEFV
                     KTTVLDNTPIRWFYRAASLESAQWAAGQTGEIRVDVERRRASREAGNVEHISGDSFIQK
                     EARPLFDVNTLQHLPDGFAVMTGLGVARMAFSSPLRVERREIPLQRFPVLAKTDPLAEF
                     RPPADGGGPKADDDFAGIY"
                     /name="TraM recognition domain-containing protein"
     BGC             1..7455
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          8783..9195
                     /name="ColRNAI_rep_cluster_1857"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="93.51"
                     /coverage="100.0"
                     /evalue="3.9599999999999998e-174"
     Typing          complement(5390..6117)
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="1.32e-150"
ORIGIN
        1 ccactggcag cagccattgg taactgggag ttcgcagagg atttgtttag ctaaacacgc
       61 ggttgctctt gaagtgtgcg ccaaagtccg gctacactgg aaggacagat ttggttgctg
      121 tgctctgcga aagccagtta ccacggttaa gcagttcccc aactgactta accttcgatc
      181 aaaccacctc cccaggtggt tttttcgttt acagggcaaa agattacgcg cagaaaaaaa
      241 ggatctcaag aagatccttt gatcttttct actgaaccgc gatccccgtc agttcagagg
      301 aggacgatgg tgccaccgtt ccaccctgaa catcccggat atagtttgcc tgacatgcga
      361 ccagaagaaa gcctgaaaaa atcaatataa aaagaaaaac aacctttacc tttttcatat
      421 accttccctg tatttaaaaa ccccggcatt catccctgaa caccggaagt ctgtatttca
      481 aatcatcctt gataactttt gcttaccagt taccatcccg gtaaacaaag gatacaaagt
      541 aatcaaattt actaatatcg attacatttt taaagtgtgg ctgtaatatc gaaacccatg
      601 atttttcaac atcaaaccaa ccattattaa tattatcctt taaaggcatc cccagacttt
      661 caatgacaga accatcatca ccgaagtctt ttgagtattc accaccttta aactcttcgg
      721 ttttcttatc aaaccaatga atatgtaatt taagccccat atttacctct taaagatatt
      781 ttttaatgtt tcgttttgga tccggccctt taacctgctt acccgttttt ggatcgaatg
      841 ccccgaggtg ttcgccatca ctggcgcggt acccttcaag ctcaccgtgc tgggaatccc
      901 attcataaat tttacgcttt ttatcaccat accatcgggc ccgcttacca ccaccacctt
      961 gtttaggggt tttaggttta ccctctttca actctcccaa ccccttaata tcttcagtct
     1021 tgggatcagg aaaataatca tggccgtaat ctttagttcc cttacgaggt tttttctttt
     1081 cctcatttaa tttattttct gcatccttcg cttttttctc cttttgtttc cggctctcca
     1141 tcgccccgga aagcgcagcc ttatccctgg ataaggattc attcatttcg tttaaagatg
     1201 tctgggcagc ttttaatttc tcattctgat tctgaatatc cttatcaaga tagcgaacct
     1261 gatcctgcca cccggagcca tattcatgag gcgggttata agtcacaaaa tcatctttat
     1321 ttgcctctgc ctcttttacc tttttatcgg cttcctgaac agcagccctt gcaccgggga
     1381 tcgccttctc tgtcgatgca atgcgactgt ttaaggtcgc aatattttta tcttcagcat
     1441 ccagctcagc tttcgcttta tcatactctc ttttcagccc ctcttccggg tgagcagcgt
     1501 cccatgcctg ctggcgacgc ttttcttcct ccagacgctg ttttacctgt gccggagtaa
     1561 gaacatccgt caccgacaca tagaccggtt tctgtccgct ctctttcggg aaacgaataa
     1621 cggcctcacg ggagttacca ccggccgtaa aaccagccgg acgtgaatca cctttttcag
     1681 caataatgcc ttttggcggg gctttcgcgg ccggaacacc tttaggtacg ctcacctgca
     1741 gagacgggag acccggaatc gacacactga atacccccgg acgttttgtc ggtttcgcat
     1801 ccaccacagg aacactcatt ggccggccgg tgacaaccgc aatatgctgc cgctcgtcct
     1861 tcacaatatc cgccacacgt ttagtgacgc tgaccgtcgc ctggtccagc ggcagggagc
     1921 tgaccggcgt ctctgttacc gtgtctgccg gcaatgacgt cacgattttt gacatcattt
     1981 tcggatcatc ttttgctatc tcagaaggca gcactccgta aatcgcaatc ccccacagac
     2041 caaacttaaa cggacctttc agggcagcca gcacatcagc aacagcggcc gacaacgcat
     2101 cgccggaaac ggataaagcc agtccttcag cccccggagt ggccagggca ggcagaccga
     2161 aggccatcgc ggtggccgaa gactgtccgc caccagagct cccgctatga ttgccgctgt
     2221 taccgccatt accaccgggt ttactcccgc cgttaccaaa ctcccccggg ttatagttat
     2281 gaatatcccc gttaggtgta tgcgtcgtac cccagcccgg cccgctgttt ggatccgtac
     2341 caccacctga tgaagggcca cctttacctg atgtaccgtt cacattccca ctggcctgac
     2401 caccattgtg tcccagacct gaattacccg gacctcgtcc gtctccgcca ctcatatact
     2461 tttcctcttt gacttttaaa acaataaact aaaataaaat actgtacata taaccactgg
     2521 ttttatatac agtataaaaa ttacgctgcc ttgtttttca tgtcaagtct gtaaatttgc
     2581 gtttttgtga aaatgatcaa aaaaacagcc actcacacca tgcgcaatcc cctccagatg
     2641 caacaaaaac cagcacaaac ggcgccgttc tccggcctca gtatgtttta ctgaaatcat
     2701 tatatgagat accagaaagc cccctccggg acaggaaaag aaacgggggt ctggttcggg
     2761 ttgttcggtc actgaacacg gtcagaaact gatgataaga tagcctgcgg atatataact
     2821 caatgagaaa aaagaattaa aggtaaggag acgctcatga gacgttccgg cagcaaactg
     2881 tgtcttatcg ccatgataac agcgacagca actctcactg cctgtgctcc aaagggcagc
     2941 gtggaacagc atacccggca ttacgtatat gcttcagatg acggttttga tcccaatttt
     3001 tccacccaga aagctgacac aacacgaatg atggtgcctt ttttccggca gttctgggat
     3061 atgggcgcaa aggataaagc gaccggaaaa tcacggagtg atgtgcagca acgcattcag
     3121 cagtttcaca gtcaggaatt tttaaactca ctccaaggca caacacaatt tgcgggtacc
     3181 gattaccgca gcaaagacct cacaccgaaa aaatcaaggc tactggctga caccatttca
     3241 gctgtttatc tcgatggcta tgaaggcaga cagtaagtgg atttaccata acgcgtcatt
     3301 acgcgcaccg ctcagacggg ctcagggcgt ttccggcggc tacgggataa aacaggcaac
     3361 aacccccccg gaaaactgcc ggaaacgcgc ccgataaatt ttatcctaat gcatgcctat
     3421 gcacgcaact gcatggcata tgttttgacg taaaatggat gccgtaagcc cttttttacc
     3481 gactttctgc ttcatcagcc tgactgacac gaccatattc tttcagaccg ccccctgcta
     3541 aacttccttc atattgccgc attaacccgg gaggctccgc aatgagcaac actacacact
     3601 acgaaaacgc caactttctt cgggaactgg ctgaaagcct gccccgcata ctgccggaag
     3661 gtggcccgga caaagctgcg ctgttgcagc gactggctaa cgaagaactg gcccaggcag
     3721 agtatgaaga tcaggttcgc gccaaagtga ccgccgcccg tgctgacacg cgtccgggta
     3781 tgaccacgga acaactccgc cagcgcctgc atggccgtta tcaggaactg cgcgatgccg
     3841 tatgacgtgg aatggaagca gggagccatc gaggatgtaa cgacgctgtt tgactatatc
     3901 gcggaaaatt catccctgtg ggatgcgcag aacgttaccg accgggttct cgctgcggcg
     3961 gacaaactgg ccgacttccc gcgactctat gaagtggact cacgctatgg cgaggacgtt
     4021 cgccggatca gtctgatggg acagcatgtc ctctatgatg ttgatgacca gaccagaaaa
     4081 gtccgggttc tggccgtggt cggccagcgc cagaatcccc atattgttct ctaataaccg
     4141 gtgacgggga cgcaattcat tgcgtggccg tcgccggttg gacaagcaca gcgcgtcagc
     4201 gttttcccca cggccaccac cggcgcggtg ttccggccgg ggtctctgct gtctccggtt
     4261 tgtgttccag cagtctcatg gactgcattt cctgccgtag cccggccacc tcctccctga
     4321 gtgcttttat ctccgcgatc aacgcgtcgg aggccatttt ttcagtctca cccgacagtc
     4381 tcaactcgtc ccgctcgtga gtctcatcct gtcttaactc accgtacacc cggataagct
     4441 cgctggtatc caccacccgg ccgccatcag cttccgtacg gtatgatacg cggcctttcg
     4501 ccatatcccg atacagggaa cttcgggctt tacccgtcag ttccgtcgcc tgtctcaccg
     4561 tcacccacgc cattgtctca ccccgctatt tttgagacag tatacctgac aggcgcacac
     4621 catgcccgga aggaaagaat catgacaaaa caggaaaaaa cagccctcaa tatggctaaa
     4681 tttattaagg agcagtcgct gctattgctc gataaactga acgagctgga tatggatacc
     4741 ccggccgaca tgtgcgagcg gctacacgag gatgcggaaa cactctggca ggtgatgcgg
     4801 gataagctcg gggaggaata acagcaccgg catggccggt gctggcattt attttttgcc
     4861 gaacggccac caccggcggg caggtttgtc ctccggcagt tcaggtaccg gcacgttaaa
     4921 atagcggctg ttatattccc gcatcagctc cgctttcagc ttctcgttca ccgcgctttc
     4981 cccgtgccgc tcactcacca cgtcaatcat cgcgttaatc tgctccggtg agcacttccc
     5041 ggcatcaacc acctgcacac cgttctcgat ggcgaaccgc tccaccttgc gatagaggta
     5101 atcacacagc ttcattcctg tgggtttgtt ccgttcccat tgcggatttt taccagtgaa
     5161 aaagtacgtg gctttttcgt cgctgttgag ccgctcgtca tacatcccga tggatttcat
     5221 catcgccaga tgctgggccc ggtcgacaaa acagaaaaca tacgccccgg tctgccaggc
     5281 gagcaccacc atatcttcca gatgctcgct ggtcggcatg atgcagcgct cgccgttccg
     5341 gtcctccgcg tcttcaataa ataccatgta cagcgccata atccctcact ccgttgtcat
     5401 aaatttaaag cacgcaaaca accgttcacg atccagctct gccgttttgc gggcctcgcc
     5461 ggtctgtggg ttcacgattt catccaccga caggattgcc cgctgcaccc tgacctgcgt
     5521 cgcccggtcc gggcagatgt accagatttc atcgatgccg ttagctttgc ggttgaacag
     5581 atacccggac accacttcct gataccggcg acggctcttg acggtgcgct ccacctcaaa
     5641 cgccaccgtt ttaccgtcca gctccgccag ggcgtccggc actttcatgc ctttaagact
     5701 cagacggtgc agaatgcgcc agccggtggc ccctctggct tccatatcaa ggcgcaggga
     5761 ttgcacggcc agccggtgcg gcagatgtgc tgccgacacc cttgacggct gaaacggaat
     5821 aacatccgcc agcggttcgt cctcgtcgaa cgagaacgcc acgccatgcg gcgtcagccc
     5881 ccacacgctg acctgacggc cgtccaccgg atatttggtc cggaccagca gccctttcgc
     5941 caccaggctg tcgaggaagc ggtagaccgg ctgcaccgcc gcaatcccca gccgccgcgc
     6001 aaccagctcc gccgtggaac acagctcttc ccgcaaccag cgcagggtca gccgggtttt
     6061 ctccgcgttc cgcgcctgtc gtttcgcgtg gctgacgttg tacagctcca gcgccatcag
     6121 taaatccccg caaaatcatc atccgctttc ggcccgccgc cgtcggccgg gggccggaac
     6181 tccgccaggg gatcggtttt cgccagcacc gggaaacgct gcaacgggat ttcccggcgc
     6241 tcaacccgca gcggactgct gaacgccatc cgggccacac ccagcccggt catgaccgcg
     6301 aacccgtccg gcaggtgttg cagggtgttc acgtcaaaca gcggccgcgc ctccttctgg
     6361 atgaagctgt ccccgctgat atgctccacg ttccccgcct cccggctggc acggcggcgc
     6421 tccacgtcca ccctgatttc cccggtctgc cccgccgccc actgcgcgga ctccaggctg
     6481 gccgcccggt aaaaccagcg gatcggcgtg ttatccagta ccgtggtttt cacaaattca
     6541 gcgggcagat cctgcccgca ctgcccgaaa tcgcccagcg actggtgcgc gagcaacaga
     6601 ttgcagtccc ggctgcgcag cgtccccagt gcgttcagta catacttcga cagcagatat
     6661 ttaatttcat cgagcatcac gctgacgtgt ggccactccc ggaactcgtc ccgcgcaatg
     6721 atgatttgcg cgcagcgggc aaacagcatt ttttgcacac ggatcaccgc ctcgtcgtcc
     6781 atcgagccga taacgtacag gcagccgccg ccgttgataa tccccgccac atcgatacca
     6841 ctgtccgtct gcaggacgct caggtcagcg acgttttcca gcctagtgat caaccccttc
     6901 acgtcctttt tcagggcctc cggcagcgcg tacgccgccg ccagcacctg ctgaatgttt
     6961 gccccctgcg gaaactgctc cgcaatcagc ttcgccgctt tctgctcgct gatgcggtag
     7021 tggtccgcca cgtcgccggt ctcgcccagg ttaagcccgg caatcagcag gtttttcagc
     7081 gcgtactggt cgagatcgcg gaacagattc agctgcgccg gtttccccgg ccgcagatcc
     7141 agcagggtga agtccggaca gtgcgcccgg aagacgtgcg gcgcccatgc gtcccctttg
     7201 gggtcgaagt acaccaccgc gtccccgaaa tcgcgtacgc agcgaatgag cgcgttggtg
     7261 gccatcacgc tcttgccgct cccgggcagg ccgaggatct gaatgttggt cttgcgccag
     7321 gtatcacgcg gaaccagcac cggcttgccc tgctcatcct tacccagaaa caccgcctgc
     7381 tcctgccggg cctgctccga ggaaaaatcg gccagcgcat taaccggtac cggctccccg
     7441 aaatgcaggt ggcgcacgtc ggtcatctct cctgtccgct ggctgctgcg ccggctctcc
     7501 tgattcagtt tcgcgttcac cgcctcgtca gcagccgcaa aatgaccgtc aagcagcagg
     7561 aacgccagca gccgcgccaa cacaatcccg acagccagcc cgcccgcgca ccaggcaatc
     7621 ccgaacaggt tagccggctg cagcaggtaa taatctgcgt ttgcgtagag gtccggacgc
     7681 aggacggttt ctccccagct ctcgataaac acggcgacaa ccagcccccc cagaagggcc
     7741 agaccggccg cgccggtcag ccagtacgcg tagttccaga catgtcgacg tgccctgacc
     7801 atccgcccgg gcgaatccag cgaggccagc accgaaaatg gcgctggccg tttattatcg
     7861 cgcttatagc gatcggcata ctcccgtcgc tccttatgac tcagccccac aaaacgcatc
     7921 cgtccggccc aaagttcagc cagaccgaaa aacaggccga taactaggaa agccccggcc
     7981 agaccgtaat actcctggta cagccagctg acccacggat aaatctgccg ggccagctcc
     8041 ggaatgtgcc acttccaggc aagcgaatcc gtattaaaca tgttctctct ccttcagacg
     8101 atggtttgcc ggcgtgatgt gcagcccccg ctgcacaagc cgcggacatg ccccaaggca
     8161 tggcggcggc ggtcacgtcc gtggtgattg cgttcagctt tcaccacgga ggccagcctc
     8221 tttccgcccc atgcggaaaa ggcgcagccc cggaggaaca acgagcacgc cccagcgtgt
     8281 gagaggaaaa ggcggcaccc cagtgcggtc ttttccggtg ttccggcccc cgtcaggcgt
     8341 gagcctgacg ggggccgggt gaatttctgg cgtggccggc gtccagccgg acggagccag
     8401 aaagaggggg agagaccgtg cgtcggtggc gtccagccag cgtaagcagg ggatatcccc
     8461 ctgaggtcag ccacgccctc gcggggatga cctgtatttc tccgtaagga gaaaaaagca
     8521 acagagatag gttaacgtaa aatgttcagc gaaaaaccga tatgattcac ctatcctggt
     8581 aatttattat cagggaatat aaagacttaa tcaggggaca atatgccaca tcagcgcgtc
     8641 cggtgtccgt cttgtaggtg ccggggaaat tgcgcctcct cgctcactcg gtcgctacgc
     8701 tccggccgtg agactgcggc gggcgctgcg gacacatgca aagttaccca cagattccgt
     8761 gaataagcag gggactaaca tgtgaggcaa aacggcaagg ccacgcaggt ggcgtttttc
     8821 cataggctcc gccctcctga ctgagttcac ataaacagac gctttttcgg tgcatctgtg
     8881 ggagccggtg gctcaaccat gaatcagtca ggagtggcga aacccgacag gacttaaaga
     8941 tcatcaccgt ttccgatgaa tcgctccctc ttgcgctctc ctgttccaac cctgccgttt
     9001 cccggatacc tgttccgcct ttctcccttg cgggaagtgt ggcgctttct catagctcac
     9061 actctggtat ctcggctcgg tgtaggtcgt tcgctccaag ctgggctgta agcaagaacc
     9121 ccccgttcag cccgactgct gcgccttatc cggtaactgt tcacttgagt ccaacccgga
     9181 aaagcacgca aaacg
//
