LOCUS       NZ_CP023375             6800 bp    DNA     circular CON 14-JUN-2024
DEFINITION  Escherichia coli strain 1283 plasmid p7, complete sequence.
ACCESSION   NZ_CP023375
VERSION     NZ_CP023375.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN07618124
            Assembly: GCF_002310735.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6800)
  AUTHORS   Argyle,S.A.
  TITLE     Passive-aggression: the convergence of plasmid architectures driving
            emergence of multi-drug resistance in a clonally diverse Escherichia
            coli population from a veterinary clinical care setting
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6800)
  AUTHORS   Argyle,S.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-SEP-2017) Infection and Immunity, The Roslin
            Institute, Easter Bush Campus, Edinburgh EH25 9RG, United Kingdom
            (Great Britain)
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: De-novo v. Celera Assembler 8.5
            Assembly Name                     :: 1283
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 20x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002310735.1-RS_2024_06_14
            Annotation Date                   :: 06/14/2024 02:45:57
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,839
            CDSs (total)                      :: 4,718
            Genes (coding)                    :: 4,491
            CDSs (with protein)               :: 4,491
            Genes (RNA)                       :: 121
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 13
            Pseudo Genes (total)              :: 227
            CDSs (without protein)            :: 227
            Pseudo Genes (ambiguous residues) :: 0 of 227
            Pseudo Genes (frameshifted)       :: 75 of 227
            Pseudo Genes (incomplete)         :: 166 of 227
            Pseudo Genes (internal stop)      :: 33 of 227
            Pseudo Genes (multiple problems)  :: 43 of 227
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP023375.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..6800
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="1283"
                     /host="canine"
                     /db_xref="taxon:562"
                     /plasmid="p7"
                     /geo_loc_name="United Kingdom: Scotland, Edinburgh"
                     /collection_date="2002"
     gene            join(6732..6800,1..372)
                     /locus_tag="CNQ51_RS25085"
                     /old_locus_tag="CNQ51_25080"
     CDS             join(6732..6800,1..372)
                     /locus_tag="CNQ51_RS25085"
                     /old_locus_tag="CNQ51_25080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011161230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_005119689.1"
                     /translation="MAWHTVQETLKLTGKSRSQLYRDMAKGLVSYRTGKNDRREFETSE
                     LIRAYGELRTSETPKRHKEGHSKSVVSQAENAQLDVIQQKLDALQQTVTLMLEDKMARE
                     AENRLRNEEREQLQAEISRLADALAQEKKRGFWSRLFRSGSE"
                     /name="hypothetical protein"
     gene            complement(1149..1298)
                     /locus_tag="CNQ51_RS26250"
     CDS             complement(1149..1298)
                     /locus_tag="CNQ51_RS26250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017880354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001138880.1"
                     /translation="MPSEYDEQLDSTDTQLPGEYDLFDLMAQVTEENLHAPVDFGSPVG
                     REAL"
                     /name="hypothetical protein"
     gene            1869..2027
                     /locus_tag="CNQ51_RS26775"
                     /old_locus_tag="CNQ51_25090"
     CDS             1869..2027
                     /locus_tag="CNQ51_RS26775"
                     /old_locus_tag="CNQ51_25090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007772075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_032287700.1"
                     /translation="MHEPPVQSDRCALSGNYQLESNPERHDKTPLAAAISNRSAREDRL
                     RGLEVEA"
                     /name="hypothetical protein"
     gene            2487..3302
                     /gene="sul2"
                     /locus_tag="CNQ51_RS25105"
                     /old_locus_tag="CNQ51_25100"
     ARG             2488..3299
                     /name="sul2"
                     /gene="sul2"
                     /gene_name="sulfonamide-resistant dihydropteroate synthase
                     Sul2"
                     /tool="amrfinderplus"
                     /drug_class="SULFONAMIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            3363..>3890
                     /locus_tag="CNQ51_RS25110"
                     /old_locus_tag="CNQ51_25105"
                     /pseudo=""
     CDS             3363..>3890
                     /locus_tag="CNQ51_RS25110"
                     /old_locus_tag="CNQ51_25105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010890156.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase"
                     /name="phosphotransferase"
     gene            3911..4384
                     /gene="dfrA14"
                     /locus_tag="CNQ51_RS25115"
                     /old_locus_tag="CNQ51_25110"
     ARG             3912..4381
                     /name="dfrA14"
                     /gene="dfrA14"
                     /gene_name="trimethoprim-resistant dihydrofolate reductase
                     DfrA14"
                     /tool="amrfinderplus"
                     /drug_class="TRIMETHOPRIM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            <4459..4734
                     /locus_tag="CNQ51_RS25120"
                     /old_locus_tag="CNQ51_25115"
                     /pseudo=""
     CDS             <4459..4734
                     /locus_tag="CNQ51_RS25120"
                     /old_locus_tag="CNQ51_25115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010890156.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside phosphotransferase APH(3')"
                     /name="aminoglycoside phosphotransferase APH(3')"
     gene            4734..5570
                     /locus_tag="CNQ51_RS25125"
                     /old_locus_tag="CNQ51_25120"
     CDS             4734..5570
                     /locus_tag="CNQ51_RS25125"
                     /old_locus_tag="CNQ51_25120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000480972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(6)-Id"
                     /protein_id="WP_000480968.1"
                     /translation="MFMPPVFPAHWHVSQPVLIADTFSSLVWKVSLPDGTPAIVKGLKP
                     IEDIADELRGADYLVWRNGRGAVRLLGRENNLMLLEYAGERMLSHIVAEHGDYQATEIA
                     AELMAKLYAASEEPLPSALLPIRDRFAALFQRARDDQNAGCQTDYVHAAIIADQMMSNA
                     SELRGLHGDLHHENIMFSSRGWLVIDPVGLVGEVGFGAANMFYDPADRDDLCLDPRRIA
                     QMADAFSRALDVDPRRLLDQAYAYGCLSAAWNADGEEEQRDLAIAAAIKQVRQTSY"
                     /name="aminoglycoside O-phosphotransferase APH(6)-Id"
     gene            complement(<5677..6081)
                     /locus_tag="CNQ51_RS25130"
                     /old_locus_tag="CNQ51_25125"
                     /pseudo=""
     CDS             complement(<5677..6081)
                     /locus_tag="CNQ51_RS25130"
                     /old_locus_tag="CNQ51_25125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001120888.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS91 family transposase"
                     /name="IS91 family transposase"
     gene            complement(6125..6514)
                     /locus_tag="CNQ51_RS25135"
                     /old_locus_tag="CNQ51_25130"
     CDS             complement(6125..6514)
                     /locus_tag="CNQ51_RS25135"
                     /old_locus_tag="CNQ51_25130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000102614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000102614.1"
                     /translation="MSTELNSGTVGGFGHMGPNDPYNDGHSGSGSSGGSFNGGGNGGHD
                     NSSGSSYTASFGLITGRHPITVPGTKNINSVDLSAVINNIIHHEGARNNMYLDTANNVR
                     VGVTGTGWQCLATAGISAEGKRTFR"
                     /name="hypothetical protein"
     ARG             4735..5567
                     /name="aph(6)-Id"
                     /gene="aph(6)-Id"
                     /gene_name="aminoglycoside O-phosphotransferase APH(6)-Id"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             4490..4734
                     /name="APH(3'')-Ib"
                     /gene="APH(3'')-Ib"
                     /gene_name="APH(3'')"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="100.0"
                     /coverage="30.34"
     ARG             3364..3905
                     /name="APH(3'')-Ib"
                     /gene="APH(3'')-Ib"
                     /gene_name="APH(3'')"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="99.43"
                     /coverage="67.42"
     Typing          complement(1334..1507)
                     /name="MOBP"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="99.429"
                     /coverage="100.0"
                     /evalue="1.19e-84"
     Typing          1431..2036
                     /name="rep_cluster_2335"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="89.593"
                     /coverage="99.0"
                     /evalue="0.0"
ORIGIN
        1 atggctaaag gccttgtcag ctatcgcaca ggaaaaaatg atcgccggga gttcgagacc
       61 agtgaactga ttcgggccta tggcgagctg cgcacttctg agacaccaaa aaggcacaag
      121 gagggacact ccaaatctgt cgttagccag gcggaaaatg ctcagctaga cgtcattcag
      181 cagaaactgg acgctctgca gcagactgtt accctaatgc ttgaagacaa gatggcgcgg
      241 gaagcagaaa accgcctgcg aaatgaggag agggaacaac tacaggccga aattagccgt
      301 ctggctgacg cgctggcaca ggaaaaaaag cggggattct ggtcgcggct gtttcgctcc
      361 ggttcagagt aacagtgcag gtgactctga tttaccataa catctgttat cagcaccgcc
      421 tgagaggccc tcagggcgtt tctgacggga aaccggtaaa acaggcaaca aaccacccga
      481 aaacccgcca gaaacgcgca ggctctgttt ttacggcatg catgagtatg cgcacaagtg
      541 catagcgcgg aaattcacac cattcagccg gggtaagtcc tgtttccggc gttcttccca
      601 tccgaaaacg gtgaacgggg acgcaattta ttgcgtggcc gtgaagcgtt gccggcgcag
      661 ccggaaaacc cgctgtcagc acgttcagga agggggtgat gtacaaatgg cacagaggat
      721 gaaagtgacg tatgagctga aggaatgatg taaaagtgat gtaaaagtga tgtataagtg
      781 atgtaaaagt gatgtataag tgatgtaaaa gtgatgtatg aactgaagga gcgatgtaat
      841 tctgtagtca ggaagaataa cccgttcatg caggcatgaa cgatacagtg aggaacgctt
      901 ttttgtcacg atctcccctt aacctgcgta aatcacccgc catggttgat tatttttcaa
      961 cctcaaaatg gtcatacacc taacgcagcc gcgattttca tcgcaactgc atgaattaaa
     1021 agaaaaaaaa ggaatatttc gttttcacga gtaatacccg ggtattaaaa atccactgta
     1081 attacatgaa aataaagaaa taaaaggtaa taccggagta ttaccacgta cgcgggcaag
     1141 cgaaaaagct ataacgcttc ccggccgaca ggcgacccaa aatccacagg ggcatgcagg
     1201 ttctcttcag taacctgcgc cattaaatca aaaaggtcat attcgccggg aagctgcgta
     1261 tcagtcgaat ccagttgttc atcatattca gatggcatgg ggtgatatcc agtagctgag
     1321 aggttgttag cgggtttcgg ggcgcagccc tgaaccagtc atgtagcgct agcggagtgt
     1381 atactggctt actatgttgc cacgattgcg aaaatcagtg aagtgcttca tgtggcagga
     1441 gaaaaaaggc agcaccggcg cgtcagcaga atatgcgata caggagatat tccgcttcct
     1501 cgctcactga ctcgctacgc tcggtcgttc ggctgcggcg agcggtaccg gcttacggac
     1561 ggggacggaa atttcctgga agataccagg aagacactta gcaaagaaga gataaggcca
     1621 cggcgaagcc gtttttccat aggctccgcc cccctgacaa gcatcgcaaa atctgacgct
     1681 caaatcagtg gtggcgaaac ccgacaggac tataaagatc ccaggcgttt ccccctggta
     1741 gctccctcgt gcgctctcct gttcctgcct ttcggtttac cggtgtcatt ccgctgttat
     1801 ggccgcggtt tctcattcca cgcctgacac tcagttccgt gaaggcagtt cgctccaagc
     1861 tggactgtat gcacgaaccc cccgttcagt ccgaccgctg cgccttgtcc ggtaactatc
     1921 aacttgagtc caacccggaa agacacgaca aaacgccact ggcagcagcc attagtaaca
     1981 ggagtgcacg agaagataga ttaagaggtc ttgaagtaga ggcctgactg cggctacact
     2041 gaaagaacag ttttggtaat ggcggtctcg tgaaccctgt taccgggtta agcagttccc
     2101 caactgactt aaccttcgaa caaaccgcct ccccaggcgg ttttttcgtt tacagagcaa
     2161 gagattacga ttcattgaaa aggatctcaa gaagatcctt tgtagattac tatcaattaa
     2221 tcttccgaac atgacaccag tcactgttga ttacggttaa accgctccgt aacaggtttc
     2281 cctcgtattg gtgacttgca gcaccaaaga agcaaaaaag ataaatatat ctacttattg
     2341 agagatgata tatttatttc caaaatgcta cagatacatc atcatgaaac ggatcaccgc
     2401 aaacaggtta ctcgcctggg gattcccttt cgacccgagc atccgtatga gactcatgct
     2461 cgattattat tattatagaa gcccccatga ataaatcgct catcattttc ggcatcgtca
     2521 acataacctc ggacagtttc tccgatggag gccggtatct ggcgccagac gcagccattg
     2581 cgcaggcgcg taagctgatg gccgaggggg cagatgtgat cgacctcggt ccggcatcca
     2641 gcaatcccga cgccgcgcct gtttcgtccg acacagaaat cgcgcgtatc gcgccggtgc
     2701 tggacgcgct caaggcagat ggcattcccg tctcgctcga cagttatcaa cccgcgacgc
     2761 aagcctatgc cttgtcgcgt ggtgtggcct atctcaatga tattcgcggt tttccagacg
     2821 ctgcgttcta tccgcaattg gcgaaatcat ctgccaaact cgtcgttatg cattcggtgc
     2881 aagacgggca ggcagatcgg cgcgaggcac ccgctggcga catcatggat cacattgcgg
     2941 cgttctttga cgcgcgcatc gcggcgctga cgggtgccgg tatcaaacgc aaccgccttg
     3001 tccttgatcc cggcatgggg ttttttctgg gggctgctcc cgaaacctcg ctctcggtgc
     3061 tggcgcggtt cgatgaattg cggctgcgct tcgatttgcc ggtgcttctg tctgtttcgc
     3121 gcaaatcctt tctgcgcgcg ctcacaggcc gtggtccggg ggatgtcggg gccgcgacac
     3181 tcgctgcaga gcttgccgcc gccgcaggtg gagctgactt catccgcaca cacgagccgc
     3241 gccccttgcg cgacgggctg gcggtattgg cggcgctgaa agaaaccgca agaattcgtt
     3301 aactgcacat tcgggatatt tctctatatt cgcgcttcat cagaaaactg aaggaacctc
     3361 cattgaatcg aactaatatt ttttttggtg aatcgcattc tgactggttg cctgtcagag
     3421 gcggagaatc tggtgatttt gtttttcgac gtggtgacgg gcatgccttc gcgaaaatcg
     3481 cacctgcttc ccgccgcggt gagctcgctg gagagcgtga ccgcctcatt tggctcaaag
     3541 gtcgaggtgt ggcttgcccc gaggtcatca actggcagga ggaacaggag ggtgcatgct
     3601 tggtgataac ggcaattccg ggagtaccgg cggctgatct gtctggagcg gatttgctca
     3661 aagcgtggcc gtcaatgggg cagcaacttg gcgctgttca cagcctatcg gttgatcaat
     3721 gtccgtttga gcgcaggctg tcgcgaatgt tcggacgcgc cgttgatgtg gtgtcccgca
     3781 atgccgtcaa tcccgacttc ttaccggacg aggacaagag tacgccgcag ctcgatcttt
     3841 tggctcgtgt cgaacgagag ctaccggtgc ggctcgacca agagcgcacc gttaacccag
     3901 gatgagaacc ttgaaagtat cattgatagc tgcgaaagcg aaaaacggcg tgattggttg
     3961 cggtccagac ataccctggt ccgcgaaagg ggagcagcta ctttttaaag cattgaccta
     4021 caatcagtgg cttctggtgg gtcgcaagac gtttgaatct atgggcgcac tccccaatag
     4081 gaaatacgcg gtcgttaccc gctcaggttg gacatcaaat gatgacaatg tagttgtatt
     4141 tcagtcaatc gaagaggcca tggacaggct agctgaattc accggtcacg ttatagtgtc
     4201 tggtggcgga gaaatttacc gagaaacatt acccatggcc tctacgctcc acttatcgac
     4261 gatcgacatc gagccagagg gggatgtttt cttcccgagt attccaaata ccttcgaagt
     4321 tgtttttgag caacacttta cttcaaacat taactattgc tatcaaattt ggaaaaaggg
     4381 ttaacaaagc tatgcaatcg acggcaaaaa gcttcgttcg cttcgcgcac tacgcctttt
     4441 tccgcgattg atagcgacga tatggttgtt tgccatggtg atccctgcat gccgaacttc
     4501 atggtggacc ctaaaactct tcaatgcacg ggtctgatcg accttgggcg gctcggaaca
     4561 gcagatcgct atgccgattt ggcactcatg attgctaacg ccgaagagaa ctgggcagcg
     4621 ccagatgaag cagagcgcgc cttcgctgtc ctattcaatg tattggggat cgaagccccc
     4681 gaccgcgaac gccttgcctt ctatctgcga ttggaccctc tgacttgggg ttgatgttca
     4741 tgccgcctgt ttttcctgct cattggcacg tttcgcaacc tgttctcatt gcggacacct
     4801 tttccagcct cgtttggaaa gtttcattgc cagacgggac tcctgcaatc gtcaagggat
     4861 tgaaacctat agaagacatt gctgatgaac tgcgcggggc cgactatctg gtatggcgca
     4921 atgggagggg agcagtccgg ttgctcggtc gtgagaacaa tctgatgttg ctcgaatatg
     4981 ccggggagcg aatgctctct cacatcgttg ccgagcacgg cgactaccag gcgaccgaaa
     5041 ttgcagcgga actaatggcg aagctgtatg ccgcatctga ggaacccctg ccttctgccc
     5101 ttctcccgat ccgggatcgc tttgcagctt tgtttcagcg ggcgcgcgat gatcaaaacg
     5161 caggttgtca aactgactac gtccacgcgg cgattatagc cgatcaaatg atgagcaatg
     5221 cctcggaact gcgtgggcta catggcgatc tgcatcatga aaacatcatg ttctccagtc
     5281 gcggctggct ggtgatagat cccgtcggtc tggtcggtga agtgggcttt ggcgccgcca
     5341 atatgttcta cgatccggct gacagagacg acctttgtct cgatcctaga cgcattgcac
     5401 agatggcgga cgcattctct cgtgcgctgg acgtcgatcc gcgtcgcctg ctcgaccagg
     5461 cgtacgctta tgggtgcctt tccgcagctt ggaacgcgga tggagaagag gagcaacgcg
     5521 atctagctat cgcggccgcg atcaagcagg tgcgacagac gtcatactag atatcaagcg
     5581 acttctccta tcccctggga acacatcaat ctcaccggag aatatcgctg gccaaagcct
     5641 tagcgtagga ttccgcccct tcccgcaaac gaccccaaac aggaaacgca gctgaaacgg
     5701 gaagctcaac acccactgac gcatgggttg ttcaggcagt acttcatcaa ccagcaaggc
     5761 ggcactttcg gccatccgcc gcgccccaca gctcgggcag aaaccgcgac gcttacagct
     5821 gaaagcgacc aggtgctcgg cgtggcaaga ctcgcagcga acccgtagaa agccatgctc
     5881 cagccgcccg cattggagaa attcttcaaa ttcccgttgc acatagcccg gcaattcctt
     5941 tccctgctct gccataagcg cagcgaatgc cgggtaatac tcgtcaacga tctgatagag
     6001 aagggtttgc tcgggtcggt ggctctggta acgaccagta tcccgatccc ggctggccgt
     6061 cctggccgcc acatgaggca tgttccgcgt ccttgcaata ctgtgtttac atacagtcta
     6121 tcgcttagcg gaaagttctt ttaccctcag ccgaaatgcc tgccgttgct agacattgcc
     6181 agccagtgcc cgtcactccc actcttacat tgttcgcagt atctaggtac atgttattgc
     6241 gtgcaccttc atgatgtata atgttattaa tgacagcaga aagatcgaca gaattaatat
     6301 tcttcgtacc tgggacagtt atcgggtgtc ggccagtgat gagaccaaag gatgcagtat
     6361 aagatgaacc actactatta tcatggccac cattaccacc accgttaaaa ctacctcccg
     6421 aacttccaga gccgctatga ccatcattgt aggggtcatt tggtcccatg tgaccaaaac
     6481 caccgacagt accgctattt aactctgtac tcataaaatt atcctctttg acttttaaaa
     6541 acagcaaaaa ctgtatttat aacaatgtgt ttatatacag tattcgaaat actacgcccg
     6601 tcaaaaccac accgtcaaca ggttttttgt gtatttttca cgcctcacgg gcagcctcag
     6661 accttttgtg ttaaaacagt aatatgttct gctgttacaa tacggtacac acaggagaca
     6721 ctgtcacttt tatggcatgg cacacagttc aagagacact gaaattaaca ggaaagtcgc
     6781 gctcgcaatt atatcgtgac
//
