LOCUS       NZ_CP023021             9024 bp    DNA     circular CON 05-JAN-2024
DEFINITION  Acinetobacter baumannii strain 9201 plasmid pAba9201a, complete
            sequence.
ACCESSION   NZ_CP023021
VERSION     NZ_CP023021.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN07520236
            Assembly: GCF_003522665.1
KEYWORDS    RefSeq.
SOURCE      Acinetobacter baumannii
  ORGANISM  Acinetobacter baumannii
            Bacteria; Pseudomonadota; Gammaproteobacteria; Moraxellales;
            Moraxellaceae; Acinetobacter; Acinetobacter calcoaceticus/baumannii
            complex.
REFERENCE   1  (bases 1 to 9024)
  AUTHORS   Salgado-Camargo,A.D., Castro-Jaimes,S., Silva-Sanchez,J.,
            Volkow-Fernandez,P., Castillo-Ramirez,S. and Cevallos,M.A.
  TITLE     Evolution of Acinetobacter baumannii plasmids
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9024)
  AUTHORS   Salgado-Camargo,A.D., Castro-Jaimes,S., Silva-Sanchez,J.,
            Volkow-Fernandez,P., Castillo-Ramirez,S. and Cevallos,M.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-AUG-2017) Evolutionary Genomics Program, Center for
            Genomic Sciences, National Autonomous University of Mexico (UNAM),
            Av. Universidad s/n Col. Chamilpa, Cuernavaca, Morelos 62210, Mexico
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes hybrid assembly v. 3.7.1
            Assembly Name                     :: 9201
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 502.299x
            Sequencing Technology             :: Illumina MiSeq and PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/04/2024 20:32:01
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,108
            CDSs (total)                      :: 4,013
            Genes (coding)                    :: 3,921
            CDSs (with protein)               :: 3,921
            Genes (RNA)                       :: 95
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 92
            CDSs (without protein)            :: 92
            Pseudo Genes (ambiguous residues) :: 0 of 92
            Pseudo Genes (frameshifted)       :: 20 of 92
            Pseudo Genes (incomplete)         :: 58 of 92
            Pseudo Genes (internal stop)      :: 21 of 92
            Pseudo Genes (multiple problems)  :: 6 of 92
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP023021.1.
            Bacteria available from Submitting center.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..9024
                     /organism="Acinetobacter baumannii"
                     /mol_type="genomic DNA"
                     /strain="9201"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:470"
                     /plasmid="pAba9201a"
                     /geo_loc_name="Mexico: Guadalajara"
                     /collection_date="2013-08"
                     /collected_by="Hospital Central de Guadalajara"
     gene            522..1349
                     /locus_tag="Aba9201_RS20665"
                     /old_locus_tag="Aba9201_20635"
     CDS             522..1349
                     /locus_tag="Aba9201_RS20665"
                     /old_locus_tag="Aba9201_20635"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_057689930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OXA-24 family carbapenem-hydrolyzing class D
                     beta-lactamase OXA-72"
                     /protein_id="WP_000713530.1"
                     /translation="MKKFILPIFSISILVSLSACSSIKTKSEDNFHISSQQHEKAIKSY
                     FDEAQTQGVIIIKEGKNLSTYGNALARANKEYVPASTFKMLNALIGLENHKATTNEIFK
                     WDGKKRTYPMWEKDMTLGEAMALSAVPVYQELARRTGLELMQKEVKRVNFGNTNIGTQV
                     DNFWLVGPLKITPVQEVNFADDLAHNRLPFKLETQEEVKKMLLIKEVNGSKIYAKSGWG
                     MDVTPQVGWLTGWVEQANGKKIPFSLNLEMKEGMSGSIRNEITYKSLENLGII"
                     /name="OXA-24 family carbapenem-hydrolyzing class D
                     beta-lactamase OXA-72"
     gene            complement(1418..2176)
                     /locus_tag="Aba9201_RS20670"
                     /old_locus_tag="Aba9201_20640"
     CDS             complement(1418..2176)
                     /locus_tag="Aba9201_RS20670"
                     /old_locus_tag="Aba9201_20640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017393773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_015060804.1"
                     /translation="MALDKSKKRGRPAQLLQIAELHAFVDYLSQKKDRSDLQNDVIAML
                     RIEKFNFESLSEAEQILVKEALKPYREHMKLNLLFDEVSVKYPQTAYERKFVQLFEAYR
                     DNALSGADFNILKTMATRYLSFKAHKLELSDLELYLSQIQKKEASKKRTAENHRKFELG
                     GAVLAAFKELGIDISQDTPEQMKNRIQNTKKFHDDVMKSKIYQEVKSYKNGYFERNKLF
                     HQVLEGLNTWKKDGELLSVIEIKKALVKNQ"
                     /name="hypothetical protein"
     gene            2480..3649
                     /locus_tag="Aba9201_RS20675"
                     /old_locus_tag="Aba9201_20645"
     CDS             2480..3649
                     /locus_tag="Aba9201_RS20675"
                     /old_locus_tag="Aba9201_20645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002011489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /protein_id="WP_012846858.1"
                     /translation="MASYHFSVKSKNKGYALSHYLYISRLMQYEGIRKKSAEVLEHVEP
                     GQCMPSWVKDPVEFWQAADTFERANAKAYMEYEIALPNEFTVEQRKTLVETFVDKTIAT
                     HHYPHSYAIHNVKSRLSGEEQPHCHLMFSLKADDGIERSPEQYFKRYNAKEPSKGGAKK
                     IQLQDGHADYTTYLLHIRKAWENHLNDALAEHSPTVTYQIDGQKIQIKNQVSADNYEKY
                     NEIHGTLYLPEPKLGTGKQNETVEYLAEIQKIRQHNAKERELEQRQQYFDQQHEYYYSC
                     SNEPFSSPEVMHYLNHLIKKASNKKELGHDIDEIIQTQQPILHHEKWDIDTINFNLNNA
                     RLYPEPDMEFKVRSVQPKPVIEPTSPKSKPEIQPSQPEPKRNDYDGPGF"
                     /name="MobA/MobL family protein"
     gene            4187..5074
                     /gene="repM"
                     /locus_tag="Aba9201_RS20680"
                     /old_locus_tag="Aba9201_20650"
     CDS             4187..5074
                     /gene="repM"
                     /locus_tag="Aba9201_RS20680"
                     /old_locus_tag="Aba9201_20650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360254.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein RepM"
                     /protein_id="WP_012780181.1"
                     /translation="MDKNQIVKSNQVIEASYQLSAVEQRIVLAAISRIPKSQPITDDEL
                     YPVSVNELQLLGVHEKTAYRDLKEGINRLYERSINLSIDDKSIKMRWVQEIQFLDSQSI
                     IGIRFSKPILPFISNLSREFTKYALSDIAGINSGYGIRIYELLVQYRQIGKREISVENL
                     RSMLELGKKYPLFADFKKRVIDTAVDQINECSPLSVSYEQKKTGRKVTHIQFSFKEKSK
                     SINHLNEPEKFYKLTDAQVHMFGNQLSRLHELSHLATQGESYDDLAATIKEMLRDPIQQ
                     KQFIPHLRNLGFKG"
                     /name="repM"
     gene            5151..5708
                     /locus_tag="Aba9201_RS20685"
                     /old_locus_tag="Aba9201_20655"
     CDS             5151..5708
                     /locus_tag="Aba9201_RS20685"
                     /old_locus_tag="Aba9201_20655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017398013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid replication DNA-binding protein"
                     /protein_id="WP_012780177.1"
                     /translation="MKSLSVIELSNLYGMTRQAVYKQINKGNLSKNSDGKIDLSEAIRV
                     FGEPSKYVNSLQTTETRKLSEVHLLEQQVHMLQKQLEQAHEREKFQRDELKAKNDQLHV
                     KDEQIEAMQRLLEAPKTNMTTFADQKPSQDIATDPRPEPEPKHDGLTTPVEIENKRIPV
                     PEQVELEQPKRGWLSRFFLPNG"
                     /name="plasmid replication DNA-binding protein"
     gene            complement(5903..6178)
                     /locus_tag="Aba9201_RS20690"
                     /old_locus_tag="Aba9201_20660"
     CDS             complement(5903..6178)
                     /locus_tag="Aba9201_RS20690"
                     /old_locus_tag="Aba9201_20660"
                     /inference="COORDINATES: protein motif:HMM:NF015807.4"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Arc family DNA-binding protein"
                     /protein_id="WP_075911389.1"
                     /translation="MIKKYTQVNFRLPLDLKEEIEQSASLTGNSITAEIVERLRNSFEY
                     DNLMLDNIELQSELINLESEKLDLLLEYQDKLCKIQDQILEELKKK"
                     /name="Arc family DNA-binding protein"
     gene            6272..6670
                     /locus_tag="Aba9201_RS20695"
                     /old_locus_tag="Aba9201_20665"
     CDS             6272..6670
                     /locus_tag="Aba9201_RS20695"
                     /old_locus_tag="Aba9201_20665"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_075911388.1"
                     /translation="MSNIIEFKRNERRFINQKPISPVELVTNILTPQEVDIKSLIKETK
                     KILREKGLKFRTSHQDLEHLKGNNLILFSKKKCGFILTTKLACSTNSSWEIYSISIDKT
                     TKALDIVNKIISRLGDNVHGSSREEAIS"
                     /name="hypothetical protein"
     gene            6639..6857
                     /locus_tag="Aba9201_RS20700"
                     /old_locus_tag="Aba9201_20670"
     CDS             6639..6857
                     /locus_tag="Aba9201_RS20700"
                     /old_locus_tag="Aba9201_20670"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_075911387.1"
                     /translation="MAAAEKKQSANPAMEAAKEAANIKIDGFEQGVNTYNAIGSQLLRE
                     KRDPSVINKTRENRRNIRKAREAIKNL"
                     /name="hypothetical protein"
     gene            complement(6946..7680)
                     /locus_tag="Aba9201_RS20705"
                     /old_locus_tag="Aba9201_20675"
     CDS             complement(6946..7680)
                     /locus_tag="Aba9201_RS20705"
                     /old_locus_tag="Aba9201_20675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005207180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_075911386.1"
                     /translation="MTPPHILLEENYNKPLIPLPVYFSYENILESKYFYNQREGGIFCL
                     KELQASEGSEYSGCIELFYCEFNNEYALDGVCAVADEYLDEYDAANKALEAYEVEKEIL
                     IARYAFKDIEIINDSIKITGKQIKGASILANYQRNGVSSFIYKYLLKKYGVLVCDNYQT
                     YKGHMLWVLSIVKLSVIRIYDLTKKEFIGTFDKVSPCLIKPWSVPYNFPSDKEKFLRLD
                     ACVYTELEFHSLVLVTFAEDMF"
                     /name="hypothetical protein"
     gene            complement(7699..8019)
                     /locus_tag="Aba9201_RS20710"
                     /old_locus_tag="Aba9201_20680"
     CDS             complement(7699..8019)
                     /locus_tag="Aba9201_RS20710"
                     /old_locus_tag="Aba9201_20680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005207183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_012780178.1"
                     /translation="MFTRTVQTLKNSTDLVQRFTMPNIRQTFELRRFSEKEKNKQYILI
                     FKDIILNKKDWDDVKVVAEIQERNNSLRFSIKASKQYPELTSYEKMLEAKINDIIKPTL
                     VA"
                     /name="hypothetical protein"
     gene            8170..8580
                     /locus_tag="Aba9201_RS20715"
                     /old_locus_tag="Aba9201_20685"
     CDS             8170..8580
                     /locus_tag="Aba9201_RS20715"
                     /old_locus_tag="Aba9201_20685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005207185.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_075911385.1"
                     /translation="MLNFELKEKWGENSLILGFTQIPTTLIYAQKELGLSSIEINILLN
                     LLTHWWKKEEFPYPSQAGIAYRMGVSTRTVQRTLAGLETKGFITRNKTSRDNSKYKGRS
                     IYDLSPLVKILEEKAPDLDIVKKIKKNKRLAK"
                     /name="helix-turn-helix domain-containing protein"
     ARG             523..1346
                     /name="blaOXA-72"
                     /gene="blaOXA-72"
                     /gene_name="OXA-24 family carbapenem-hydrolyzing class D
                     beta-lactamase OXA-72"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     Typing          4188..5074
                     /name="rep_cluster_1364"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          2559..3646
                     /name="MOBQ"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 tttataagtt aaagcaaggc ttactcagtt cttatatgcg agaacaactc agaaagcctg
       61 atattgtgat gctattttct gggctatagt gcattatttt tttactttta tgcgtaagtc
      121 ctaaggtcac ttttttattg ttccaaatcc tctttacagt ttttttgttc tctactttac
      181 aattgacttg ggaaattatc ccgatgtttg tccgcaggaa atggggataa aagtgggtta
      241 ttggagcatt gagaaatcag gaaaaattaa atttttgagt attttttaat cgattttgtt
      301 ggctaaaagt gacaaagttg cttaaaaagc atccgacttg tttccaagtc ggcttttcac
      361 ctatttttta gtcatgacta attctataaa taattaaaaa ataataactt ttcataattt
      421 atttcgcata acgcccatta tgttaaatta aaagagtttt aactttttta ataaaagtat
      481 tatgctctaa gccccaaaat ttcccctaac atgaatttgt aatgaaaaaa tttatacttc
      541 ctatattcag catttctatt ctagtttctc tcagtgcatg ttcatctatt aaaactaaat
      601 ctgaagataa ttttcatatt tcttctcagc aacatgaaaa agctattaaa agctattttg
      661 atgaagctca aacacagggt gtaattatta ttaaagaggg taaaaatctt agcacctatg
      721 gtaatgctct tgcacgagca aataaagaat atgtccctgc atcaacattt aagatgctaa
      781 atgctttaat cgggctagaa aatcataaag caacaacaaa tgagattttc aaatgggatg
      841 gtaaaaaaag aacttatcct atgtgggaga aagatatgac tttaggtgag gcaatggcat
      901 tgtcagcagt tccagtatat caagagcttg caagacggac tggcctagag ctaatgcaga
      961 aagaagtaaa gcgggttaat tttggaaata caaatattgg aacacaggtc gataattttt
     1021 ggttagttgg cccccttaaa attacaccag tacaagaagt taattttgcc gatgaccttg
     1081 cacataaccg attacctttt aaattagaaa ctcaagaaga agttaaaaaa atgcttctaa
     1141 ttaaagaagt aaatggtagt aagatttatg caaaaagtgg atggggaatg gatgttactc
     1201 cacaggtagg ttggttgact ggttgggtgg agcaagctaa tggaaaaaaa atcccctttt
     1261 cgctcaactt agaaatgaaa gaaggaatgt ctggttctat tcgtaatgaa attacttata
     1321 agtcgctaga aaatcttgga atcatttaat aatttctaaa attaacataa tacgccttat
     1381 gcgaaatttg cctgaatagc ctttctcaga aaggctatta ctgatttttc actaaagctt
     1441 tcttaatttc gatgactgac aataactctc cgtctttttt ccaggtattc agtccctcta
     1501 atacctgatg aaaaagctta tttctttcaa aatatccatt tttataactt ttaacttctt
     1561 gatatatctt agatttcatt acatcatcat gaaatttttt cgtattctga atgcgattct
     1621 tcatctgttc aggcgtatct tgactaatat caatccctaa ctccttgaaa gcagctaaca
     1681 cagcaccgcc caactcaaac ttacgatgat tttcagccgt tctttttttg ctggcttcct
     1741 tcttctggat ctgactcaaa taaagctcta aatcactcaa ctcaagctta tgcgctttga
     1801 aactcagata acgagtcgcc atggttttca agatattaaa atcagcacca ctcaacgcat
     1861 tgtcccgata agcctcaaac aactgcacaa acttccgttc atatgcggtc tgcggatact
     1921 tcacagacac ctcatcaaac aataagttca gcttcatatg ctcacgataa ggttttaagg
     1981 cctctttcac caagatctgt tcagcttcag acaatgactc aaagttaaat ttttcaattc
     2041 gtagcattgc aatcacatca ttctgcaaat cagaacgatc cttcttctgt gaaagatagt
     2101 ctacaaatgc atgtaactct gcgatttgta aaagttgtgc aggtctgcca cgtttttttg
     2161 atttatccaa tgccatctat ctgccgccta attttcagaa ctgctaccga ttgagttatg
     2221 gttttaccat aattcaatcg ggcagtctga aaataattat ttaaaataaa aataaaattt
     2281 cttgaaaaga atttatattt ttattttaaa taattcgcac ttgacagttt ctcctaatcg
     2341 gagaaactag tacgcaatgg ggcgattccc ccttgacccc ctttaaccgg attatttcag
     2401 ccctgtaggc attacataat ccggagattt ttattgcgtt tcactccata aaaaccaaca
     2461 acaccccaag gaagtgaaca tggccagtta ccatttcagc gtcaaaagta aaaataaagg
     2521 ctacgcactg agccactacc tgtacatttc ccgactcatg caatacgaag gcatccgcaa
     2581 aaagagtgca gaagtcctcg aacatgtcga accagggcaa tgcatgccct cctgggtcaa
     2641 agatccggtt gaattctggc aagcagcgga cacctttgaa cgggccaatg ccaaggctta
     2701 catggaatac gaaattgccc taccgaatga attcaccgta gaacaacgta aaacgctcgt
     2761 agagacattt gttgataaaa ccatagcaac acaccactac cctcattcct acgccataca
     2821 caacgtaaaa tcacgcctca gtggtgaaga acaaccccat tgccacctca tgttttcact
     2881 caaagccgat gacggcatag aacgaagtcc ggaacaatac ttcaaacgct acaacgctaa
     2941 agaaccaagc aaaggcggag caaagaaaat tcaactacag gatggccatg ccgactacac
     3001 cacttacctc ctacatatcc gaaaagcctg ggaaaatcac ctgaatgatg cattggcaga
     3061 acatagccca accgtgactt accagatcga tggccagaag atccaaatta aaaaccaagt
     3121 ttcggcagac aactacgaaa aatacaacga gatacacggc accctctacc taccagaacc
     3181 caaactgggg acaggcaaac aaaatgaaac cgtggaatac ctagcggaaa tccagaaaat
     3241 cagacaacac aatgccaaag aacgagaact ggaacagcgc caacaatact ttgatcaaca
     3301 gcatgaatac tactacagct gctcaaacga acccttcagt tctccggaag tgatgcacta
     3361 cctcaatcac ctcattaaaa aagccagtaa caaaaaagaa ctgggccacg atatcgacga
     3421 aattattcaa actcagcaac caatcctgca tcacgaaaaa tgggatatcg ataccatcaa
     3481 ttttaatctc aataacgcca ggttataccc agaaccggat atggagttta aagtccgatc
     3541 cgtacaacca aaaccagtga ttgaaccaac atcaccgaag tcaaaacctg aaatacaacc
     3601 ctcacagcct gaaccgaaac gaaatgatta tgatggtccg ggtttttaaa aatggatcta
     3661 gatcagaaag tacaaagcga gtgtctacga gcgacatcac caaaattagc gcctcgactt
     3721 tctgaaaaac cgctttttaa ggctgtatag cctaaaaaag cataaatcag atgctaaaac
     3781 tggcttccag accgagcgaa gcgagcaaaa agctttatga gcgaagcgaa ttccgagttg
     3841 cttttgctct tgcctttact ttttctcaaa ttcacgaagg aattaacaga aaaattgccc
     3901 cctgaatcga gcgaaagcga gattcaatag agtttgagcg tagcgaaaac cacgggcaat
     3961 tttttcaaac gtctttttta attattttta tatcttttaa atcttttctt tgagctgtat
     4021 cccttatgga gcaagccttt caaagtttaa ctatgacgga ttgactacta actatgacgg
     4081 attgactact aactatgacg gattgactac ttaactatga cggattgact actaactatg
     4141 acaagtatat agttgtcata tataaaagaa aatcaatggt tttattttgg ataagaatca
     4201 aattgttaaa tcaaatcaag ttatagaagc ttcctatcaa ttaagtgctg tagaacagcg
     4261 tatcgtcttg gcagctattt cacgtattcc gaagagccag cctattactg atgatgagtt
     4321 ataccctgta agcgttaatg aactacagtt attaggagta catgaaaaaa ccgcatacag
     4381 agacttaaaa gaaggaatta atagacttta tgaaagatct attaatctta gtattgatga
     4441 taaatctata aaaatgaggt gggtacaaga gatccagttt ttggatagtc aaagtatcat
     4501 tggtattcgt ttttcaaaac ctatcttgcc cttcatatct aatttaagta gagaatttac
     4561 taagtatgct ctatcagata ttgctgggat caatagtgga tatggtattc gtatttatga
     4621 attattggtg caatacagac aaataggtaa gcgtgaaatc tctgttgaga acttacgaag
     4681 catgttggag cttggcaaaa aatacccact atttgcagat ttcaaaaaac gggtaattga
     4741 tactgctgta gaccaaataa atgaatgcag cccattaagc gtttcctatg agcaaaaaaa
     4801 aactggtcgt aaagtcactc atattcagtt ttcatttaaa gaaaagtcca aaagcattaa
     4861 tcatctcaat gagccagaga agttttataa attaactgat gctcaagtcc atatgtttgg
     4921 caatcaactt tctcgtctac atgaactatc tcatttagcg actcaaggag aaagttacga
     4981 tgatctagct gcaacaatca aagaaatgct aagagatcca atacaacaaa agcaatttat
     5041 tcctcatctt aggaatttag gttttaaagg atgatgtttg attgtgtatg tagcggttga
     5101 ctgtttcttg atgtatctta gttcacataa tagacaacct aaattacaac atgaaatcac
     5161 tatctgttat cgagctttca aacctctatg gaatgactcg tcaagccgtt tataaacaaa
     5221 taaataaagg taatttaagt aagaatagtg atggtaaaat tgatctttct gaggccattc
     5281 gtgtctttgg tgagccatct aaatatgtaa acagtttaca gacaaccgaa acacgaaagt
     5341 tgtcagaagt tcacttactt gaacagcagg ttcacatgct tcaaaaacag cttgaacaag
     5401 ctcatgagcg tgagaagttt caacgagatg aattaaaagc taagaatgat cagttacatg
     5461 ttaaggatga acaaattgag gctatgcaac gcttattaga agccccaaaa accaatatga
     5521 ctacgtttgc cgatcagaaa cctagccagg atatagcaac ggatcctcga ccagaaccag
     5581 agccgaaaca tgacggattg actactccag ttgaaataga aaataagcgg attccagtgc
     5641 cggagcaggt tgaactggag cagccgaaaa gagggtggtt aagccggttt ttcttaccta
     5701 atgggtaaaa ggcttgttta ggtgtactaa tcaaagttgt gaaacattac tcaaataata
     5761 ggcgtggaac gtgaataatc atgaaaaagc cgttctagtg cgctgaactc tagaacggct
     5821 ttgactaaac tattgatgct tataagaaaa tttcaagcat ttcgcataag gcgtattatg
     5881 ttaattttag aaaaccttaa atctattttt tctttaattc ctctaaaatt tggtcttgta
     5941 tcttacataa tttatcttgg tattctaaaa gtaaatctaa tttctcagac tctaaattaa
     6001 ttaattcgct ttgtaactct atattgtcaa gcatcaaatt atcgtattca aaactattcc
     6061 tgagtctttc tactatttct gctgtaatag aattaccagt aagactagct gactgttcta
     6121 tttcttcttt taaatcaaga ggaagtctaa aattaacctg ggtatacttt ttaatcatga
     6181 aattctagag tctaaaatgt cttgaataac tatagcacat ttgctatata ttattatagc
     6241 aaatgtgcta taacatttgg agtagctata tatgtccaac attattgaat ttaaaagaaa
     6301 tgaaaggaga tttattaatc aaaaacctat cagtcctgta gaactagtga caaatatact
     6361 cactccacaa gaggtagata taaagtcttt gattaaggaa acaaagaaaa ttttaagaga
     6421 aaaaggctta aaatttcgta cttctcatca agatttggaa cacttaaaag gaaataattt
     6481 aatattattt tccaaaaaga aatgcgggtt tatcttaacc acaaagttag cctgtagcac
     6541 aaatagctca tgggaaatat attccataag tatagataag acgacgaaag cattagatat
     6601 tgttaataaa attatatcta ggctaggaga taacgttcat ggcagcagca gagaagaagc
     6661 aatcagctaa tccagcgatg gaagcagcga aagaggcagc aaatattaaa attgatggct
     6721 ttgagcaagg tgtaaatacc tacaatgcga ttggttcaca attattgcga gaaaagcgag
     6781 atccaagtgt aattaataaa actcgtgaaa atagacgaaa tattcgaaaa gcacgagaag
     6841 ctatcaagaa tttatagtaa aaagcttctt aagatctaaa atataaaaaa ttctcattaa
     6901 acaagcccta agaaattctc agggctttgt tcatgataaa aattatcaga acatgtcttc
     6961 tgcaaaagtg actaaaacaa ggctgtgaaa ctccaattcc gtatatacac aagcatctag
     7021 tctaagaaat ttttccttat cagatggaaa attataaggt acagaccaag gttttattaa
     7081 acaaggactt accttatcaa aagttccaat aaattccttt ttagttaaat cataaattct
     7141 gattacactt aacttaacaa tactcaaaac ccaaagcatg tggcccttat aggtctgata
     7201 attatcacaa accagcacac catacttttt taataagtat ttgtatataa atgaggaaac
     7261 tccatttcgc tgataattgg ctaaaatcga tgcacctttt atttgtttac ctgttatttt
     7321 aatagagtca ttaataattt cgatatcttt aaatgcgtat ctcgctatca aaatttcttt
     7381 ctctacttca taagcttcta aggctttatt agcagcgtca tattcatcta aatattcatc
     7441 agcaacagca caaaccccat ccaatgcata ctcattatta aattcacaat aaaaaagctc
     7501 aatacatcca gaatactcgc taccttctga agcttgcaat tcttttaaac aaaatattcc
     7561 accttccctt tggttgtaga agtacttact ttcaagaata ttttcataag aaaagtaaac
     7621 aggtagtgga attaaaggct tattataatt ttcttcgaga agtatgtgtg gaggagtcaa
     7681 tttaaacctt atatttcatc aagctactaa tgttggttta ataatatcat taattttagc
     7741 ttctaacatt ttctcataag aagttaattc tggatactgt ttggatgctt taatagaaaa
     7801 tcttaagcta ttatttcttt cttgaatttc agctacaact ttcacatcat cccaatcttt
     7861 tttattgaga ataatatctt tgaaaataag tatatattgc ttattttttt ctttctcaga
     7921 aaaacgtctt agttcaaatg tttgacgaat attaggcata gtaaaacgct gaactaaatc
     7981 agtactattt ttgagggttt gaacagttct agtgaacatt ttgacaccta catacctaaa
     8041 gaaataaaag aaaataaaaa tatatagtga caggttataa gacaaatatg tcactatcaa
     8101 ctacgtcaaa tttggcgtac tatatatata ttaatttata tatatatatg aatagggttt
     8161 taaaaaatta tgttaaattt tgaattaaaa gaaaagtggg gcgaaaactc tctaatatta
     8221 gggttcacgc agatcccaac tactctaatt tatgcacaaa aagagcttgg tctatcatct
     8281 atagaaatta acatcttact taacttattg acccattggt ggaagaaaga agaatttcct
     8341 tatccatctc aagctggaat tgcatatcga atgggagttt ctactagaac tgtacaacga
     8401 acattagcag gtcttgaaac aaaaggattc ataaccagaa acaaaacatc aagagataac
     8461 agtaaataca aaggaaggag tatttatgat ttatctccat tagtaaaaat tctggaagaa
     8521 aaggcacctg atctagatat tgtgaaaaaa attaaaaaaa ataaaagact agctaaatag
     8581 atttaacata aaatctctta cgataagtca aaaaagggag cttaaagctc cctttttcta
     8641 tctaactata tgaatcttcg gtgatgtttg tatacctaat tgcctgaaaa tatgccatag
     8701 agctatgttg cgatactggt acatagcaat ttgtgaaaaa tcaaaccatt gttcggatgt
     8761 gaattggttt atatcagaaa aaggtggata acctcttaga gctagaaatg cattaatttc
     8821 ttctaccatt ggatcgagct caaacatgtt ttaaaaccta ataaagaata aagtccaatt
     8881 gtaaatcccc tttaaaaggt taggacttac gcattaactt gcaaattctt acagaaaggt
     8941 agagactagg atgtagccta caattataag atattgtaat taaatgaata aagtatcaaa
     9001 tggtttagat tttcgtcagg acta
//
