LOCUS       NZ_CP022721            20730 bp    DNA     circular CON 16-MAY-2024
DEFINITION  Staphylococcus aureus strain 135 plasmid pPS00087.1A.1, complete
            sequence.
ACCESSION   NZ_CP022721
VERSION     NZ_CP022721.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN07340894
            Assembly: GCF_003354925.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 20730)
  AUTHORS   Chako,K., Divya,B., Pak,T., Sause,W., Kumar,K., Sebra,R., Deikus,G.,
            Attie,O., Rose,H., Lewis,M., Li,Y., Bashir,A., Kasarskis,A.,
            Schadt,E., Richardson,A.R., Torres,V. and Shopsin,B.
  TITLE     Colonizing and infecting subclones diverge during Staphylococcus
            aureus infection
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 20730)
  AUTHORS   Sullivan,M.J., Altman,D.R. and van Bakel,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-AUG-2017) Genetics and Genomic Sciences, Icahn School
            of Medicine, One Gustave L. Levy Place Box 1498, New York, NY 10029,
            USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.2.0
            Expected Final Version            :: yes
            Genome Coverage                   :: 40.960746633x
            Sequencing Technology             :: PacBio; Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003354925.1-RS_2024_05_16
            Annotation Date                   :: 05/16/2024 01:22:00
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,721
            CDSs (total)                      :: 2,639
            Genes (coding)                    :: 2,573
            CDSs (with protein)               :: 2,573
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 66
            CDSs (without protein)            :: 66
            Pseudo Genes (ambiguous residues) :: 0 of 66
            Pseudo Genes (frameshifted)       :: 32 of 66
            Pseudo Genes (incomplete)         :: 32 of 66
            Pseudo Genes (internal stop)      :: 21 of 66
            Pseudo Genes (multiple problems)  :: 18 of 66
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP022721.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..20730
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="135"
                     /isolation_source="nares"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="pPS00087.1A.1"
                     /geo_loc_name="Germany"
                     /lat_lon="51.9636 N 7.6132 E"
                     /collection_date="1994"
                     /collected_by="University of Munster"
     gene            join(20730,1..626)
                     /locus_tag="CGP86_RS14065"
     CDS             join(20730,1..626)
                     /locus_tag="CGP86_RS14065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000593103.1"
                     /translation="MIKLENVFVKKGNKNILDGCNFNFEKGKSYALVGESGAGKSTLLN
                     IIAGFEDVSQGSIYIEDKLLKKKVDFYRYTLGYLFQNFALLENQTISQNLDLALKFKKN
                     KKDNMNLKKEVLKKVGLDLDIKRIVSSLSGGEQQRVALARLILKDPKIILADEPTGSLD
                     TKNGKIVIDLLLKLLDENKTMIVVTHDLELAKRFDVIVNISELRS"
                     /name="ABC transporter ATP-binding protein"
     gene            864..1493
                     /gene="mobV"
                     /locus_tag="CGP86_RS14380"
                     /pseudo=""
     CDS             864..1493
                     /gene="mobV"
                     /locus_tag="CGP86_RS14380"
                     /inference="COORDINATES: protein motif:HMM:NF013258.4"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /name="mobV"
     gene            1587..2132
                     /locus_tag="CGP86_RS14080"
                     /old_locus_tag="CGP86_00004"
     CDS             1587..2132
                     /locus_tag="CGP86_RS14080"
                     /old_locus_tag="CGP86_00004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001805533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000273005.1"
                     /translation="MYEIKTKNVGGWFHKEKQETGNIVITKTDFEKYTKQIKAAQMILD
                     DYECIKSGKSLKKAEKQNESLVNELTSVHMENEKLVEEFNDLAQRYNYLLSENEKKDKE
                     LNYTLKLFNQVFKIIKSMMKEERYHTLINHIDNHLDNSKIREVMTIDNNDEQFFKKKYQ
                     AQEREIIFKEDREDGYTL"
                     /name="hypothetical protein"
     gene            2516..3376
                     /locus_tag="CGP86_RS14090"
                     /old_locus_tag="CGP86_00005"
     CDS             2516..3376
                     /locus_tag="CGP86_RS14090"
                     /old_locus_tag="CGP86_00005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000145511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_000145511.1"
                     /translation="MTGETVVYKNEMNLVPLRRFTATEINLFFAMCNKLKEQDTNTLRL
                     SFDELKKLSNYSPETRNINRFANDLDNVYKKMLNLTIRYEDDDVIERFVLFNHYRIHKR
                     EQYLEISTSSNLKHILNSITNNFTKFELKEMTRLKSTYSKNMFRLLKQYKHTGYLKIHI
                     DDFKNRLDIPKSYRMTDINKNVFKPIIIELGSIFNNLTINKIKAKKGRKIEWIEFTFDA
                     EKRIHNKRQPQMSKIDKSRQYVRREKTPKWLEERSYEKQPQKDYDPQLEKEREDFLKQL
                     ELNWE"
                     /name="replication initiation protein"
     gene            3463..3804
                     /locus_tag="CGP86_RS14095"
                     /old_locus_tag="CGP86_00006"
     CDS             3463..3804
                     /locus_tag="CGP86_RS14095"
                     /old_locus_tag="CGP86_00006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761340.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000761341.1"
                     /translation="MKLAEAIKEQRELKGWSQEELANILKVSRQSVSKWESAKNYPSLD
                     ILIAMSDLFGISLEHLIKGDARFKKVILEGNYRESNRVPSIVDFLYDFWWLFFPVAGFL
                     VWAIHSFMG"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(4043..4114)
                     /locus_tag="CGP86_RS14100"
     CDS             complement(4043..4114)
                     /locus_tag="CGP86_RS14100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_106873653.1"
                     /translation="MNEILVHIMTTAISGCLVTLFGY"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            4263..4448
                     /locus_tag="CGP86_RS14105"
                     /old_locus_tag="CGP86_00007"
     CDS             4263..4448
                     /locus_tag="CGP86_RS14105"
                     /old_locus_tag="CGP86_00007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000466619.1"
                     /translation="MFGDQRQEATKYVIKEGYQDIYFLNKNGEWYYFEVRSVWRGKHII
                     RVKDGLLGWRKEIVTE"
                     /name="hypothetical protein"
     gene            complement(4667..5410)
                     /locus_tag="CGP86_RS14110"
                     /old_locus_tag="CGP86_00008"
     CDS             complement(4667..5410)
                     /locus_tag="CGP86_RS14110"
                     /old_locus_tag="CGP86_00008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843758.1"
                     /translation="MKSVKRLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESATEDKQKKESDNINFESKSDAQIVEILKNQINTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNAR
                     QNVDAQEKTYTTSPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAQREDVSANPND
                     NDSDIEEKSEETEPKKGFWSRLFGN"
                     /name="DUF536 domain-containing protein"
     gene            5821..6497
                     /locus_tag="CGP86_RS14270"
                     /pseudo=""
     CDS             5821..6497
                     /locus_tag="CGP86_RS14270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /name="replication initiator protein A"
     gene            <6508..6790
                     /locus_tag="CGP86_RS14385"
                     /pseudo=""
     CDS             <6508..6790
                     /locus_tag="CGP86_RS14385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199895.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            8001..8618
                     /gene="cadD"
                     /locus_tag="CGP86_RS14130"
                     /old_locus_tag="CGP86_00011"
     ARG             8002..8615
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="99.51"
                     /coverage="100.0"
     gene            8637..8984
                     /locus_tag="CGP86_RS14135"
                     /old_locus_tag="CGP86_00012"
     CDS             8637..8984
                     /locus_tag="CGP86_RS14135"
                     /old_locus_tag="CGP86_00012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119691.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNQEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            9153..9245
                     /locus_tag="CGP86_RS14140"
     CDS             9153..9245
                     /locus_tag="CGP86_RS14140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            9457..10431
                     /locus_tag="CGP86_RS14145"
                     /old_locus_tag="CGP86_00013"
     CDS             9457..10431
                     /locus_tag="CGP86_RS14145"
                     /old_locus_tag="CGP86_00013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="WP_000072391.1"
                     /translation="MSNTKIKYQIFISSTYLDLIEERQAVVEAVLNSNNIPAGMELFNS
                     SSKSQWEIITQWINESDAVILLLGSSYGTIDSEENISYTEMEYNFAKSLGKPIYVFEMN
                     KASTESAEKSKKLDEFKTKVKENRLISPNINDISELKSKVSQTLMQSVPSEIKENSGWI
                     RVQDCGKNVKKLKKLDAIQRDLDTYDFLKEELYKIFMYVKTFYFQHTPFDDSYIEDIEN
                     YLLNYENNPHKSFMKIKVYDYKNFLKHLKNILILIKQGKKPLAQAGHFKLSFYEEDLKL
                     LQKNYKTTLVDIKGLNKHFYKECDRCLKAYNIFIEGINKHLYE"
                     /name="DUF4062 domain-containing protein"
     gene            complement(10551..11366)
                     /locus_tag="CGP86_RS14150"
                     /old_locus_tag="CGP86_00014"
     CDS             complement(10551..11366)
                     /locus_tag="CGP86_RS14150"
                     /old_locus_tag="CGP86_00014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019467708.1"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_000164958.1"
                     /translation="MTKNQNFIETKEYKRFAEFCDACIKYQYIGICYGQPGVGKTLSSR
                     YYTNWDTIEKQVNHRGWEDLASKTTDDILSVDKIFYNAPAEKQTKLRNDLYSITAIIDL
                     GQKLHVVNKYGHEHSKHYSDMFKYIDLIIVDEIDRLKVQHLEQLRAIYDEHNLAMIFIG
                     MPGIEKKLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWQDLGFDLKLEDFTDYEAIT
                     TIIKITKGNFRLIHRLFAQIDRIMDINGLDKISTEVVETARDSLVIGIR"
                     /name="AAA family ATPase"
     gene            complement(11359..12802)
                     /locus_tag="CGP86_RS14155"
                     /pseudo=""
     CDS             complement(11359..12802)
                     /locus_tag="CGP86_RS14155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790716.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Mu transposase C-terminal domain-containing
                     protein"
                     /name="Mu transposase C-terminal domain-containing protein"
     gene            complement(12774..13367)
                     /locus_tag="CGP86_RS14160"
                     /old_locus_tag="CGP86_00017"
     CDS             complement(12774..13367)
                     /locus_tag="CGP86_RS14160"
                     /old_locus_tag="CGP86_00017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690636.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690638.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNQKDLNLLKTLYDNGTPI
                     KTIAEQWHVSRTTIYRYLNKLEDKEDEKQGEVSN"
                     /name="recombinase family protein"
     gene            complement(13631..14011)
                     /gene="blaI"
                     /locus_tag="CGP86_RS14165"
                     /old_locus_tag="CGP86_00018"
     ARG             complement(13635..14011)
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="99.21"
                     /coverage="100.0"
     gene            complement(14001..15758)
                     /gene="blaR1"
                     /locus_tag="CGP86_RS14170"
                     /old_locus_tag="CGP86_00019"
     ARG             complement(14005..15758)
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.56"
                     /coverage="100.0"
     gene            15865..16710
                     /gene="blaZ"
                     /locus_tag="CGP86_RS14175"
                     /old_locus_tag="CGP86_00020"
     ARG             15866..16707
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            17079..17687
                     /locus_tag="CGP86_RS14185"
                     /old_locus_tag="CGP86_00021"
     CDS             17079..17687
                     /locus_tag="CGP86_RS14185"
                     /old_locus_tag="CGP86_00021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002436987.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001566953.1"
                     /translation="MIVGYARVSSNDQNLERQLENLKTFCAEKIFTEKQSGKSIENRPV
                     LQEALNFLRMGDRFVVESIDCLGRNYDEVIHTVNYLKDKEVQLMITSLPMMNEVVGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRI
                     IYHRVVEMLEEGQSISKIAKEVNITRQTIYRIKNDNDLI"
                     /name="recombinase family protein"
     gene            18101..18394
                     /locus_tag="CGP86_RS14190"
                     /old_locus_tag="CGP86_00022"
     CDS             18101..18394
                     /locus_tag="CGP86_RS14190"
                     /old_locus_tag="CGP86_00022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="WP_000726502.1"
                     /translation="MKKKFVSSCIASTILFGTLLGVTYKAEAATVHVAGGVWSHGIGKH
                     YVWSYYSHNKRNHGSTAVGKYSSFSGVARPGVQSKASAPKAWGGNKTFYSLH"
                     /name="lactococcin 972 family bacteriocin"
     gene            18469..20403
                     /locus_tag="CGP86_RS14195"
                     /old_locus_tag="CGP86_00023"
     CDS             18469..20403
                     /locus_tag="CGP86_RS14195"
                     /old_locus_tag="CGP86_00023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001670421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="WP_000713729.1"
                     /translation="MKKFKLFLDFSTLLLISGLLFLFFFKENEEIIPESSNILTISNWD
                     KSNSKSKVLDVIESGAKNQNIQIIKSVKDFDNKKEFFVFNSKRNNSDFIRNKTSLLTPS
                     DLLNREIKGKYYIIGEHFNVEELTSELKKAGLTSEVEYINRNILFFELVIDNDLLVPFI
                     FLGVLYLLYFLYDRGYNLKFYAIQKLHGFSTTRIIFHNIHIKIIYWLVLTAIFFIANIL
                     IIHIANLELDFLMFIRRFIVLLFVFACITTLLWLISYSLLLKLSIPLILKGKKGYKFSI
                     FMGTFTKCIMVLILSFLLAQNLNAYTKLKNIYDSEKIWQKLDNYYTLEISPNIRNSEEK
                     QILETNIYNLIKKSEQLGGLLLKNNNIANPDKNNYIPENGNVFFINNNFLNFYKNINHD
                     FKMIDNHSDKINVFIPPRLQYQKSEIQKNHQGWIDFQKQQNKKVDVQVLSKNVSVFSFD
                     RTTNLKFGYLDSPIVMLLTLDDLTGDFYLAAVSQGGYLFKDLDTLKQLLKDNHLEEEIS
                     GITNYKDSVLNELNETKTKMIITIVTIIINVFILLIATVFETIQYFSWNKKQLLLRKIH
                     GYSLFSSNVRYLTISILLSIMLAYTTHILFGSKILLFIIMSIAIIQHLLQIAYIKYLEK
                     YFKDLMREI"
                     /name="bacteriocin-associated integral membrane family
                     protein"
     gene            20407..20718
                     /locus_tag="CGP86_RS14200"
                     /old_locus_tag="CGP86_00024"
     CDS             20407..20718
                     /locus_tag="CGP86_RS14200"
                     /old_locus_tag="CGP86_00024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="WP_000831610.1"
                     /translation="MKRTLIIVTIVLLIIILSLLLVRNEHLDRFNPLLKEKVSYAKVPK
                     DTQDYRNITVYSKNGEKKSYKLDFLGYDPTKEYVKVNHKGKYVRSIEYITKDIPSFLK"
                     /name="YxeA family protein"
     ARG             15866..16710
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     BGC             13101..20730
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          6848..6995
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="81.333"
                     /coverage="100.0"
                     /evalue="2.96e-25"
     Typing          2517..3376
                     /name="rep_cluster_2214"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(4668..5410)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.866"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          865..1139
                     /name="MOBV"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="94.565"
                     /coverage="100.0"
                     /evalue="4.71e-46"
ORIGIN
        1 tgataaaact tgaaaatgtt tttgtaaaaa aaggtaataa aaacatttta gacggatgta
       61 actttaattt tgaaaaagga aaatcatatg ctttagttgg agaaagtggc gctggaaaat
      121 ctactttact taacataatc gctgggttcg aagatgtatc acaaggaagc atatatattg
      181 aagataagtt actaaaaaag aaagtcgatt tttatagata tacgttaggg tatttgtttc
      241 aaaattttgc tttacttgaa aatcaaacaa tcagtcaaaa tttagattta gccctaaagt
      301 tcaaaaagaa taaaaaagat aatatgaact taaagaaaga agtattaaaa aaggtcggcc
      361 tagatttaga tatcaagaga attgttagtt ctctaagcgg tggtgaacaa caaagagtag
      421 cattggcaag attaatatta aaagatccga aaatcatttt agctgatgaa cctactgggt
      481 cactagatac gaaaaatgga aaaatagtta ttgatttatt attgaagcta cttgatgaaa
      541 ataaaactat gattgtcgta acgcatgatt tagagcttgc gaaacgattt gatgtcatag
      601 tcaatatttc tgagcttaga agttaagaaa tattgatagg tatagccata catagagaaa
      661 aaacaatatg aaatatgatt agtcattact tttgagtttt ttaatttaag gactggattt
      721 tccagtcctt ttttatgatg acaaaaaaca agcctcgcag agcacacgtt tttaatgact
      781 tatttggttt ttaataagtc tagtatgtta aaacttttct gtgtttaggt gttataatca
      841 tatgcagtgg aagttgattt attatgtctt attcaattat tcgagttgtt aaagtgaaat
      901 caaaaacaaa tacaagaggt attcaaagac atattcaaag agaaaataaa aattatgaaa
      961 atatagatat tgatttaagt aagtcatatt taaactatga tttagtcaat gatactaagt
     1021 ttgattttaa taaaaaaatt gatgagaaaa tcgaaaaaaa ttataaaggg aaacgcaaaa
     1081 ttagaacaga tgccattaaa catattgatg gattaattac atcagataat gtgtttttta
     1141 atcaattatc tgaagaagag acaaaatagt tttttaagca tgctaaagcg ttcttggaag
     1201 aagaatacgg taaagaaaat cttttatatg cgacagtaca tatggatgag ataacaccac
     1261 atatgcatta tggcgtagtt cctattacta aagatggacg tttaagtgcg aaagaagttg
     1321 taggtaataa aaaagcatta accgaattcc aagatagatt caatacgtat attaataagc
     1381 aaggctatga tttaaaacga ggaatttcta gacaacttac aaaagaaaaa catgatcaag
     1441 ttagccgtta taaacaaaaa acagaatatc ataaacaaat gcatatgcgc tagaagcaaa
     1501 tagaggatta tttaaagcaa gaaaatgata aattgataca aaactaccaa aaatcattag
     1561 atacgcttaa aaagcttctg agtgtcatgt atgaaattaa aactaaaaat gtaggtggat
     1621 ggtttcataa agagaagcaa gaaacaggta atattgtaat tactaaaact gattttgaaa
     1681 aatacactaa acaaattaaa gcagcacaga tgatattaga tgattatgaa tgtattaaaa
     1741 gtgggaagtc attaaaaaaa gcagagaaac aaaatgaaag tttagttaat gaattgacta
     1801 gtgtccatat ggaaaatgaa aagctggttg aagaatttaa tgatttagca caacgttata
     1861 attatttgtt gtcagagaat gaaaagaaag ataaagaact aaattatacg cttaagttat
     1921 tcaatcaagt ttttaaaatc attaaaagta tgatgaaaga agagcgttat catacactaa
     1981 taaatcatat tgataatcat ttagacaatt ctaaaatacg tgaagtaatg acgatagata
     2041 acaatgatga acagttcttt aagaagaaat atcaagcaca agaacgagaa atcattttta
     2101 aagaagatag agaagatggt tatacattat aaaaatagat atttaaatgc atttgtttga
     2161 ggttaattat tttttaggat gaaaaatagg tagcccccct cgaacttttt aatatatttt
     2221 tataaatctt tttaaaaacc tttttagggg cttgttcagc cctagagcaa caagggattt
     2281 caatgcctaa aggagtgttt ttgccacata aaaggagtgt ttttgccaca taaaaggagt
     2341 gtttttgcca cataaaagga gtgtttttgc cacataaaag gagtgtttta aaaagttgta
     2401 ctccttttat ggtttgacat tgataataaa gtagtttatt gtgaataaaa gttttcaaat
     2461 gggagtgtat attcaaacga tactccttta ggttcgtaat aaagggggct gtatcatgac
     2521 aggagagaca gttgtatata aaaatgaaat gaatttagtt ccattaaggc gatttacagc
     2581 tactgaaatt aatttatttt ttgcgatgtg taataaatta aaagagcaag atactaatac
     2641 attacgtttg tcttttgatg aattaaaaaa attaagtaat tatagtccag aaacacgtaa
     2701 tattaataga tttgctaatg atttagataa tgtgtataaa aagatgttga atttaaccat
     2761 tagatatgaa gatgatgatg taatagaaag attcgtttta ttcaatcatt atagaatcca
     2821 taagcgagaa caatatctag aaatatcaac ttcttcaaat ttaaaacaca tattgaattc
     2881 aattactaat aattttacaa aatttgaatt aaaagaaatg actaggctta aatctacata
     2941 ttctaaaaat atgtttagat tacttaaaca atacaaacat acaggctatt taaaaattca
     3001 catcgatgat tttaaaaatc gtttagatat acctaaatct tatcgtatga ctgatattaa
     3061 caaaaatgtt tttaaaccta ttattattga attaggttct atatttaata atcttactat
     3121 caataaaatc aaagcgaaaa aagggcgtaa aattgaatgg atagagttca catttgacgc
     3181 tgagaaacgc attcataaca aacgacaacc tcaaatgtcc aagatagata aatcaagaca
     3241 atatgtgagg cgtgaaaaga cgcctaaatg gttagaagaa cggtcatatg aaaagcaacc
     3301 tcaaaaagat tacgacccac aattagagaa agaacgagag gattttttaa aacaacttga
     3361 actgaattgg gaataacgca acttttcgtt gcgagttggt taactaaaag tatcgtgact
     3421 tttcaattat tttaattata gtttgagtta aggagtgatt ttatgaaatt agctgaagct
     3481 ataaaagaac agagagaatt aaaaggatgg tctcaagagg aattagccaa tatattaaag
     3541 gtttccagac aaagtgtttc taaatgggaa agtgccaaaa actatccttc cttagatatt
     3601 ttgattgcta tgagcgattt attcggaatc tctttagagc atttaattaa aggagatgca
     3661 cgttttaaaa aagttatttt agagggaaat tatagagaga gtaacagggt accttccata
     3721 gttgattttc tttatgattt ttggtggctt ttctttcctg ttgccggatt tttagtttgg
     3781 gccattcatt cgttcatggg ttgattttaa aatcaaaatt taatgcacat caggcaatat
     3841 gaaaaaggaa agtattttta cgacaccttg aaatgtattg ataagaatag aagagtttac
     3901 aaaaggcaat atgaaatata tactaaaagt aacaagaatt tcgtttgtaa acgcacaaaa
     3961 ccccgaacta ttcgccgtag ttcggggttt tgtggtgaat tggctttaat cgtctatatt
     4021 attttttatc acgtttatgg agctaataac caaataacgt aacgagacaa ccactgattg
     4081 ccgttgtcat gatgtgaaca agaatttcat tcataaatcg cacctcctct ctacgccgaa
     4141 ttgacatctg agagatagac gaccttcaca ttataacaaa tctctccttc catgaaataa
     4201 catgaatatt aataaatgtt gttatatatt aaagataaat aaatataagg gtgggattga
     4261 taatgtttgg cgatcaaaga caagaagcta caaaatatgt cattaaagaa ggttatcaag
     4321 atatttattt cctcaacaaa aacggggaat ggtattattt cgaagtaaga agtgtctggc
     4381 gtggcaaaca tattattaga gttaaagatg gtttgttagg ttggagaaaa gaaatagtaa
     4441 ctgaataaag atacaaaata cttgccaatg caaaagaatg aaaacgcgtc aaatcaacga
     4501 tgtataaaag atgcataaaa gataatgaaa gtaaaaagcc ataaatgccg tcatataggc
     4561 atttatggct ttttgtttgg ttaacataat cgatgattat cagaagttca attcacataa
     4621 aaaagcacgg ctaatttatg aacttgtcgt acctttttaa ttaaaattag ttaccaaata
     4681 gacgactcca aaaccccttt ttaggttccg tttcttcact cttttcttct atatcactat
     4741 cattgtcatt tggattagct gaaacgtctt ctctttgtgc ttcttcacct tgtgtacttt
     4801 cgtcgctttg acttccagat atatccttat attgaatctc tgtttcttta gtttcttcct
     4861 gatctcggtt aatatttaca ggactagtag tatatgtttt ttcttgtgca tcaacgtttt
     4921 gtctagcgtt agtagatgta tcaaagggat aattaaggtg tttttctttt tctaattgat
     4981 tttctaattt ttgaatcttt ttattactct ctaatgccag aacttgctga ttctcaagca
     5041 attttgatct ttcttgcaac tcttttctgt aaaattcaat tgttgtttca tgacgacttt
     5101 cttgtttttc aatttgatta tttaaagtat taatctgatt tttaagtatt tctactattt
     5161 gagcatcgct tttagattca aaattaatat tatccgactc ttttttttgt ttgtcttcag
     5221 tagcactttc aaaaccatat ttctttttat tttcatttac tctttgaatg attttttcta
     5281 tatcggtatc ttctttaata aacgaagtgt tttcctgttt tattgtctct atattcaatc
     5341 tcttaatatt attaaaaatc gtttgcttac taacccctaa ttcttcactc aaccttttta
     5401 cacttttcat atcatcaacc ctttataaaa tgtttataaa cccttagtaa aatattataa
     5461 gcttataacg attaataata aagtaatcga caaataaaaa tataaattcg ccaacctttt
     5521 tatcaagggt ttgtaaaggg tttatggtgt ttatcaaagg tttataaacc tatattttcc
     5581 cttttttaag tttattcaaa gtgctataat aaccttaata taacaaaaac cccaactact
     5641 ggtaatagtc ggggtttggt aataaaacgt ttagaaactg tttatttata taattttcga
     5701 tacttagatt atataatgaa taatatctta gtgcaagcac ctagattatt aaataaacac
     5761 aaaaaatgta agcgttttat tacctcttac caaactaaaa ttcggaaaga ggtttttatt
     5821 atgtcaatta aactttacaa cataaatgag gaatacagag aaaagtttta tcaaataccg
     5881 aaagtatttt ttacaaatcc taaatatatc aagttatcca atgatgcaaa aatggcatgg
     5941 ggtattctta gagatcgttt agatttatca attaaaaatg gttgggttga ttctaaaaca
     6001 ggtaatattt atttttatta caaaaatgaa aacccacaaa atatattaaa ttgtaaaaaa
     6061 gataaagtaa ttaaaataaa gaaagaactt aattgaagcc gaattactac tacaagaaag
     6121 acaaggttta aataagacaa ataaacttta tttagttaaa ccagaagtaa cagaagatga
     6181 tatttataaa attcaaaagc aagaaaacac tgttgagagc agcaatggca aggaagtcgg
     6241 aaaaaccgac ttcaagaagt cgataaaaca gaatctaatg atactgaact tagctatact
     6301 gaatctaaca atactgaaat aaatgatatg aatgacttga atgatataga gtccgaaaat
     6361 gaaattagta atcattcaag tcaatgcaag gttatttaat gcaaacaatt ttaactgaat
     6421 ttgaagaaac acatgcactt tatatgcgcc gtaaaaacat gaaacaatat aatatcttta
     6481 atcaatcatt caaatgattt tataacaatc aaagatacat caaaatattt cgttaaatca
     6541 tctgactttt taactgatag cgatgaaaaa atcaagaaat tgtcagtgat ctagaaaaag
     6601 atttgtatcg aaaacgtatg ttaagttatg gtggattgct taaataaaaa cataaaattt
     6661 taaacttaga cgatgctgaa gatggcaatt taattaatac aagtgatgaa gataaaatag
     6721 caaatgaaga agaaaaggca cattcgatta cggcaatttt gaaaagcaaa attattattt
     6781 aaggcattag tgataactga tgtctttttt tattactttt ttgtaaaaaa agtgctgtct
     6841 tatttttgtg acaaatgctg tatgtagtgt cacaaaagtg tgacacttga gctttttatg
     6901 accccacaca aaaacatttt cgaagccttg aaatatctgg ctttgccaga tcccccattc
     6961 attgatgggg acaaatttcc cttatgctct tacggagatt ttagagttaa attaaaattt
     7021 ctaagttttt gataagaaaa gccctgcagg aatttagaag aacgtgggga agttttaaag
     7081 aattttatgc taatttttaa tttgcatgta aatgggcagt gtctaaaaaa tagttattgt
     7141 ttttgctcaa atttttgttt ttgaaaatag catatattta tttggctcat atttgcgttt
     7201 taaaagcgta tataagtttt agatataaaa ctatatgaat cacccctaaa tctttaaaat
     7261 gccctcttaa aattcaaaat aagggcataa aaaataaaag cccccccaga taaagtgagg
     7321 tagctttttc tttcgacgcc gtatcgtcga tgtaattcaa aaaagttatg ggctataaat
     7381 ctacatcact ttttcaagaa tgtagtagca atattcaacg caaattaatt tttataactg
     7441 ctcggaatat ctcaagccgt ttctttaatt ttgaaataaa aaaatcgacg aaggtcgatt
     7501 acgtttttgc acatgtcgat ttatccgacg tataagtgcg cccttacggg atttaactag
     7561 attataacga cgaattttag acctgtaaag caataacaat taggtctacc aggtagataa
     7621 agtgtacaaa gtagaaccga aaaagttatt tattttgaag atttttcgta gatataattt
     7681 gctaataaac ttcctaaaac tgaataaaga aaaatagtta aactcatgta atcactccat
     7741 aattctgaag tgtctccatg tctacgcata gacacgcatt tatgccgaga aaatttattg
     7801 tgcgttgaga agaaccctta actaaacttg cagacgaatg tcggcatagc gtgagctatt
     7861 aagccgacca ttcgacaagt tttgggattg ttaagggttc cgaggctcaa cgtcaataaa
     7921 gcaattggaa taaagcacct atgattattt aaaaatataa gttataatac attcaaaaat
     7981 atttttgaat gaggtgtatt atgattcaaa cggttgttgc tgctgctgtt ctttatattg
     8041 ctacagcagt tgatttatta gtaattttat taatattttt tgctagagca aagactagaa
     8101 aagaatatag aaatatttat gttggtcaat atttagggtc tattatttta atattagtta
     8161 gtttgttttt agcttttgta ttaaattatg ttccagaaaa gtggatatta ggtttattgg
     8221 gtttaatacc aatttatctt ggaattaaag tggctattta tgatgattgt gaaggagaaa
     8281 agagagctaa aaaagaattg aatgaaaaag gattgtctaa attagttggt acggttgcaa
     8341 ttgttacgat agcaagttgt ggcgccgata atattggttt atttgttccg tattttgtga
     8401 cattaagtgt tactaattta ttacttactc tgtttgtctt tttaatttta attttcttct
     8461 tggtgtttac tgcacaaaaa ttagctaata tcccaggaat tggagaaatt gttgagaaat
     8521 ttagtcgttg gattatggct atcatttata tagctttagg tttatttatt attattgaaa
     8581 atgacactat tcaaacaatt ttaggattta tattttaatt tagggtgtga ttttatatga
     8641 gttatgaaaa tacttgtgat gtgatctgtg tacatgagga taaagttaac aatgctttaa
     8701 gttttttaga agatgataaa tctaagaaat tacttaacat tttagaaaaa atttgtgatg
     8761 agaagaaatt gaaaatcata ttatctttga ttaaagaaga tgagttgtgt gtttgtgata
     8821 tttctttgat attgaaaatg agtgttgctt caacttcaca tcatttaagg cttttatata
     8881 aaaatgaggt acttgatttt tataaagatg gaaagatggc atattatttt attaaagacg
     8941 atgaaataag agagtttttc tctaaaaatc aggagggttt ttgaaacgag tgaaacgagt
     9001 ttcttcttgt cttgatacta taaaaaacaa agttatataa cataagacga cttatcggaa
     9061 gttatctatc atcgtatatt cggagatgat ataatataca ggtcgcctat ctctcaggcg
     9121 tcaattcaga cgcagagagg aggtgcatta ctttgctaat cattttcgtt cacatcatag
     9181 caccagtcat cagtggctgt gctgttgcgt attatactta ttggcttagt aaacgcaaca
     9241 aataattaat aggcgacttt ataagccagc atcgaaaaaa tccccacact attgcagtag
     9301 tgtggggatt ggtgcattaa ttgttaatca ttttcgttat ctagattata acactggtta
     9361 gtagaggaat gcaaaaagat aatattttaa gtagtctttt tggatattat catatgatat
     9421 atttatgtaa attgattttt tattaaagga gcatatatga gtaatactaa aattaaatat
     9481 caaattttta tttcatcaac ttatttagat ttaatagaag agcgtcaagc agtagtagaa
     9541 gcagttttaa acagtaataa tattccagca ggtatggaac tttttaactc aagtagtaaa
     9601 agccaatggg aaataataac acaatggatc aatgaatcag atgcagtgat attattgtta
     9661 ggttctagtt atggaacaat tgatagtgaa gaaaatatta gctatacaga aatggagtac
     9721 aattttgcta aatctttagg taaacctata tatgtttttg agatgaataa agcatctacc
     9781 gaatccgcgg aaaagtctaa aaaattagat gagtttaaga caaaagttaa agaaaataga
     9841 ctaattagtc caaatattaa tgatatttcg gaattaaaaa gtaaagtatc tcagacttta
     9901 atgcaaagtg tacctagtga aattaaagaa aatagtggat ggataagagt acaggattgt
     9961 ggtaaaaatg taaaaaaatt aaaaaaattg gatgctatac aaagagattt agatacatat
    10021 gattttttga aagaagaact ttataaaata ttcatgtatg taaaaacttt ttatttccag
    10081 cacacaccat ttgatgatag ttatattgaa gatatagaaa actacctgct aaattatgaa
    10141 aataatccac ataaatcatt catgaaaata aaagtttatg attataaaaa ctttttaaaa
    10201 catttaaaaa acatattgat tttaattaaa caaggaaaaa agccattagc tcaagccggt
    10261 cattttaaat taagctttta cgaagaggat ttaaaattgt tacaaaaaaa ttataagact
    10321 acgctagtcg atattaaagg attgaataaa catttttata aggaatgtga taggtgctta
    10381 aaagcatata atatttttat tgagggtata aataaacatt tatatgaatg atataagtac
    10441 accctaatca tacatatata attgttgtca ctttactcga tatatgagaa tgactttacc
    10501 taataaatga gaaaagcaac gcactatatt aaaatgcgtt gctttttcta ttatcgaata
    10561 cctataacta aactatctct agctgtttct acaacttctg tacttatttt atctaaacca
    10621 tttatatcca taattctgtc tatctgcgca aataaacgat gaatcagcct aaaattccct
    10681 tttgtaattt taataatcgt cgttattgcc tcataatcag taaagtcttc gagttttaaa
    10741 tcaaatccta agtcttgcca cttatattct aatatatgat gcgtctcatc tttacttaga
    10801 ttatcaaatt catgcgcaaa acctatacgc gaatatagtt gaggataacg agatagtttt
    10861 ttctctatac ccggcatacc aataaatatc attgctaaat tatgttcatc ataaatagct
    10921 cttaattgct ctaaatgttg cactttaagg cgatcaatct catctactat aattaaatca
    10981 atatatttaa acatatcact ataatgttta ctatgttcat gtccatactt atttacaaca
    11041 tgtaattttt gacccaaatc aatgattgca gtaatactat ataaatcatt ccttaattta
    11101 gtttgttttt ctgctggtgc attataaaat attttatcca ccgatagtat gtcatcggtc
    11161 gttttactag ctaaatcttc ccaacctcta tggttaactt gtttttcaat agtatcccaa
    11221 tttgtgtaat acctagacga taaagttttt ccgacaccag gttgaccata acatatacca
    11281 atatactgat atttaataca agcatcacaa aattcagcaa agcgtttata ctctttcgtt
    11341 tcaatgaaat tttgattttt agtcattacg atatctcttt aattttttga cgtttttagt
    11401 cgtttcttga ggtgaataac cacaattttt ttcttcctta attaattccg tggtacttgg
    11461 actagcaata ttttgtttta agtgttttct tctctgacta cgagcgtgct gtatgtcttt
    11521 tatatctatg gagtaatcag ctatttctgg acatatagca gtacaaagaa attcatctct
    11581 ataaaacaca cgtatttcag ccatatcatt tgggttataa cgaatcagta catattcacc
    11641 tacataagct tctagattag tattactgta tcgaaaacct tgaaaatgaa tgccatctga
    11701 atgaactttt ctagatttag gtatttccaa caataataaa tcaagttgtt ctaagctact
    11761 tggcatatta gggaaaaagt gattactatt ccaatgactg ataggcgtgg tatgaatagt
    11821 actatgttct ttttgattat aatcttcaat taaaaagtaa cgtaattttt cttcaaaatt
    11881 gtgaaaattt attagattac taggagtatc attattgttt atatatccag gcagttgttc
    11941 taagaaagtt tgattaactg tctgaaagaa tcgttctatt tttccacgac cacgaggaac
    12001 accaactttc gaaaacatca agttaatttt caaatcaata gcgacttgtt ccatatgatg
    12061 tgaagtaaag tcacttccat gatctgtgta gaatttttcg ggtataccac acactggcca
    12121 attggtatca tttttattcc atattgcttg gtgtagtgtt aatgctgtgt tttgagcatt
    12181 ggggggcatc aaaacttaag aaatagcctg caattgcacg actatagtca tccataataa
    12241 tagttagcca tggtctattg atattacctt tttggtctaa tataaagata tctagcaaag
    12301 tatggtctgc ttgccatatt tcattgggtc tcgaggattc tctaatttgt attaaatcgt
    12361 acttattttg atagtatttt tcaccctgat gagagaaatc aataacagac ttaggcatcg
    12421 ctttaataac actataaatt tgtttataac ttggtatatc aaaattattt tctttacagt
    12481 aattagtgat tttcctatga attgtggcta tactatttct tttattcata agcgcaaggc
    12541 gttcaatttc atcaattatc tttggttcta ttttacgtgt tcctttatca gctcttgtcg
    12601 catagattag tcctttaagt ccttgttctt tatatgactt attccaccta taaagggtgc
    12661 ttaacgcaat ccctttactt ttagaaatac ttgataaaga ttgttcgcct aggataaaag
    12721 gttttataat attgtacttt tgagtagctt ttttacgttt ggcttcagaa aaattagtta
    12781 gatacttctc cttgtttttc atcttccttg tcctccaatt tattgaggta acgataaatt
    12841 gttgtacgtg aaacatgcca ctgttctgca attgtcttaa ttggcgtgcc attatcataa
    12901 agggtcttaa gtaagtttaa atctttttga tttaattttt ctggtctgcc tccatatcgg
    12961 cctctagcac gtgctgcaat tcggccagct gaagaacgct ctaaaattaa attacgttca
    13021 aattctgcaa atgctgcgaa taaatgaaat aataattgtc cagttgaact tgatttatcc
    13081 attgttatat tttcttctaa actatggaaa cttacacctc gttcgttaag ctcattaact
    13141 aatgtgatta aatcctccat attacgtccc aatctatcta atctccaaac aacaatcgta
    13201 tctcctgacc tcgcaaattc aattgcttta tctaaaccag gtcttttact ttttgaacca
    13261 ctcatatggt cattaaatat cttttcacaa ccatatgtat ttaatcgatc ctcctgtaaa
    13321 tttaaatttt gtaatccagt tgaaactctt gcataaccta ttttcaaaat acaaacctcc
    13381 tatatacatc ttcagtgtac cataacttaa ttacaaggtc ttttatgaac atagattttt
    13441 tgttgggttt ttgaacacat aatcctatgt aattcttact tatttagaca taaaagaaga
    13501 gtgtacagaa aatggttatt ttctgtacac tctcatcttt aataatatat tttaaatgtc
    13561 attaacaaaa ctaatttaat aagagtcaag catagtttac atatgtatta tgtttgaaac
    13621 atacctctaa ttacttttta ctaatatcat ttaaaatatc tcgcaattct tcaatttctt
    13681 tgttatttaa ttcttcattt ttcgcaaaat tcaacactaa acttttcata tcccctccat
    13741 acagtttatt aagaaaggtt ttagcagttt tcattttaat atcgtcttct ttaatatttg
    13801 atgagtaaaa ataaatattt tctgatttgt atcgttttat aatctctttt ttatatagtc
    13861 ttgtgattaa tgttctaatc gttttatcac taacttcttt atatttttga atttcaacta
    13921 caatttcatt agctgatact gattttttat cccatattat attcataaca tcccattcag
    13981 ccatagatat ttcaacttgc ttattggcca tttaaaacac ccattccttt taatattttt
    14041 tcacttatta attcagcatt tttcccagac gggtttccat ctgataaatg tgtagcaaaa
    14101 taatacttat catgatttgt aattacgtaa cctacaaacc acccattatt atacttcccg
    14161 tttactatac ctgtacctgt tttcccatac agttcatact tttcattttt cttaatcaat
    14221 aatgaagaag ataattgatt ctttgctttt ttactaaaat ggttattttg ttccatcata
    14281 tttttaaaaa ctattacttg ttcaagatta gatattttca aactatcttc catccaatag
    14341 cttttataac ttcccaaatt ttcattacca taatttaatt gcttgagttg agccgcagta
    14401 tagttctttg gtatttgatt actaatacgt tcgaagtacc aattaactga attttgcatt
    14461 gctgtattta aatcttgttc cttattccaa gactcgaaaa gataatgttt atgattccat
    14521 gacatacgtg aatttttatc acttataata tgacggtcaa gtccaaacag tgctaaataa
    14581 attttgtaag ttgaatcagg agaatatctt tttctacttt ctttttcatt ataaatatag
    14641 tatttgtctt tcttcatgct gtacataacg aaagatccac tatttgaacc aaaattttta
    14701 ctttcatcta aaatttggta atcgctttgt aagggctttt tataattata atcagttaag
    14761 gattgcccca ttaaaaactg gctttgaatt atcatgataa aaaaagtaaa aatacaaata
    14821 aaaattagaa ttaattttga ctgctttttc agatcggctt cttttatatt aattaatcta
    14881 tttttgagta atgatttttt accattaaat gaatggctta atatattttt gttgaaaaat
    14941 gaggttttta atacggagtc cataatagat tccgcataag ttttaaattc atttttgtta
    15001 atattattaa ggacaaatct atcggcttct acttcattgt catgaattat ctttcttttt
    15061 acaatatgta ctaatggatt gtaactcata ataatagaga agatattaaa gataattaaa
    15121 tgtaaagtat ctctattttt agcatgagca tattcatgca gtattatata ttttagtctt
    15181 ttatcaatta cacttttaaa atatgaacta ggaatcaaaa taatatattt cccataccaa
    15241 aaagttattg gagattgaat agcctctgct tttcgaatca caatattttt tttatattga
    15301 tggttgaaaa gtatcgtatc tattttattt ttttcatttt cgtttagata aagtgactgt
    15361 ttctttaaat atttaagata taataaggct ttcaaaaatt taaaacttaa aataataact
    15421 aaaactatcc aaataactgt gcagatatta tcaattgaat cccaattaaa cttatggata
    15481 tctgttgcga actcttgaac aggtttggtg gtaattatgt tatggttcaa gtcgtgtgac
    15541 ttactttcaa ctgtgggcgc ttgattattc acattattaa attttataaa agagaattta
    15601 attgggataa aaggaattaa tccagcaagc acagttagat accaaacttt ataatttaaa
    15661 ctataattaa aatagcgttt taatatgtac ctaaaaaata ctaacaatag aaatataaaa
    15721 caaaagctta ctacactcat tattagtaat ttagccattt tgacaccttc tttcaaatat
    15781 ttataataaa caattgacat caatattaca attgtaatat tattgttttg taaaaattac
    15841 aactgtaata tcggagggtt tattttgaaa aagttaatat ttttaattgt aatggcttta
    15901 gttttaagtg catgtaattc aaacagttca catgccaaag agttaaatga tttagaaaaa
    15961 aaatataatg ctcatattgg tgtttatgct ttagatacta aaagtggtaa ggaagtaaaa
    16021 tttaattcag ataagagatt tgcctatgct tcgacttcaa aagcgataaa tagtgctatt
    16081 ttgttagaac aagtacctta taataagtta aataaaaaag tacatattaa caaagatgat
    16141 atagttgctt attctcctat tttagaaaaa tatgtaggaa aagacatcac tttaaaagaa
    16201 cttattgagg cttcaatgac atatagtgat aatacagcaa acaataaaat tataaaagaa
    16261 atcggtggaa tcaaaaaagt taaacaacgt ctaaaagaac taggagataa agtaacaaat
    16321 ccagttagat atgagataga attaaattac tattcgccaa agagcaaaaa agatacttca
    16381 acgcctgctg ctttcggcaa gactttaaat aaacttatcg caaatggaaa attaagcaaa
    16441 aaaaataaaa atttcttact tgatttaatg tttaataata aaaacggaga cactttaatt
    16501 aaagatggtg ttccaaaaga ctataaggtt gctgataaaa gtggtcaagc aataacatat
    16561 gcttctagaa atgatgttgc ttttgtttat cctaagggcc aatctgaacc tattgtttta
    16621 gtcattttta cgaataaaga caataaaagt gataagccaa atgataagtt gataagtgaa
    16681 accgccaaga gtgtaatgaa ggaattttaa tattctaaat gcataataaa tactgataac
    16741 atcttatagt ttgtattata ttttctatta tcgttgacat gtataatttt gatatcaaaa
    16801 cctgattttc cctttattat tttcgagatt tattttctta attctcttta acaaactaga
    16861 aatattgtat atacaaaaaa tcataaataa tagatgaata gtttaattat aggtgttcat
    16921 caatcgaaaa agcaacgtat cttatttaaa gtgcgttgct tttttctcat ttataaggtt
    16981 aaataattct catatatcaa gcaaagtgac ataattgttg aatttatagt aactgaaacg
    17041 tatgattagg gtgtatatta attatgagat ggaaatcaat gattgttggc tatgcgagag
    17101 tatcatcgaa cgatcaaaat ttagaaagac aacttgaaaa tttaaagacg ttttgtgctg
    17161 aaaaaatatt tacagaaaaa cagtctggga aatctattga aaatagacca gtacttcaag
    17221 aagcacttaa ctttttgagg atgggagatc ggtttgtagt agaatccatt gattgtttag
    17281 gtcgtaatta tgatgaagtg attcataccg ttaattattt aaaagacaaa gaagtacaat
    17341 taatgattac tagcttacct atgatgaatg aagtggttgg caatccatta ctggataagt
    17401 ttatgaaaga tttaattatt caaatattag caatggtttc agaacaagag agaaatgaaa
    17461 gtaaacgtcg acaagcgcaa ggaattcaag ttgcgaagga aaaaggcgta tataaagggc
    17521 gccccttact ttattcacca aatgctaaag atccacagaa acgtattatt tatcatcgcg
    17581 ttgtagaaat gttagaagaa ggccaatcaa ttagtaaaat tgcgaaagaa gtaaatataa
    17641 caaggcagac gatttacaga attaaaaacg ataatgattt gatttaataa actttgtttc
    17701 aatgcaactg agagcttctc acagcgtctc aaaacagatg attataatct attatgagtt
    17761 tttaataata agacaagaaa agagagcgta aatatgctct ctctttttct cattaacgaa
    17821 tgtttataac gcaatcatga tgagagtatt aatacagtta attatttgaa atactttagt
    17881 ttatataatg ttgaattata ggtagtgaaa ttgtatttat tatacattgt catatcgttg
    17941 tttaatgata gttaatttaa ggataataga attaatatta tatatagatg aacaaaacaa
    18001 gcaacagagc agaaaaaaca cttttagatt atttttactc attctctatt ttatttattt
    18061 ttgctataat aaataaagaa tattaaatgg aggtgttttt atgaaaaaga aatttgtttc
    18121 tagttgtatt gctagtacaa tcttattcgg cactttatta ggtgtaactt ataaagctga
    18181 agctgcaaca gtacatgtag ctggtggtgt ttggagccat ggtattggaa aacattacgt
    18241 atggtcttat tatagtcaca ataaaagaaa tcatggttca acagcagtag ggaaatattc
    18301 atcttttagt ggtgttgctc gacctggtgt tcaatctaag gcatctgctc caaaggcttg
    18361 gggtggaaac aaaacatttt atagtcttca ctaattacat atattaatta aggagaatag
    18421 acagaattaa gtaaacttaa ttctgtctat tctcttgaaa gaggcaatat gaaaaaattc
    18481 aaattatttt tagattttag tactttatta ttaatttcag ggctattatt tttatttttc
    18541 ttcaaagaaa atgaagaaat tatacctgaa agttccaata ttttaacaat ctctaattgg
    18601 gataaatcta acagtaaatc aaaagtgtta gatgtcattg aatcaggcgc caaaaatcaa
    18661 aatatacaaa taattaaatc cgttaaagat tttgataata aaaaagaatt ttttgttttc
    18721 aactcaaaac gaaataattc tgactttata cgtaataaaa catcactttt aactccatca
    18781 gatttattaa acagagagat aaaaggaaag tattatatta ttggtgaaca tttcaatgta
    18841 gaagagctta cgagtgaatt aaaaaaagct ggtttaacat ctgaagttga atacataaat
    18901 agaaacatat tattttttga attagtcata gataatgatt tattagtgcc tttcatattc
    18961 ttaggcgtat tatatctttt gtacttctta tatgacagag gatataattt gaaattttat
    19021 gctattcaaa agctacatgg cttttcaact acacgcatta tttttcataa tattcatata
    19081 aaaatcattt attggctagt acttaccgct attttcttta ttgctaatat attaatcatt
    19141 catatagcca atttagaatt ggatttctta atgtttattc gtagatttat cgtgttgctt
    19201 tttgtttttg cttgtattac tacattgctg tggctgattt cgtatagtct tcttttgaag
    19261 ttaagtattc cattaatctt aaaagggaaa aaaggatata agttttcaat atttatgggt
    19321 accttcacca aatgtatcat ggtgctaata ctatcttttt tactggcaca aaatttaaat
    19381 gcttatacga agttaaagaa tatatatgac tctgaaaaaa tctggcaaaa gttagataat
    19441 tactatacat tagagatttc tcctaatatt agaaattcag aagaaaaaca aattttagaa
    19501 actaatatat acaatttaat taagaaaagc gaacaacttg gtggattgct tttaaagaat
    19561 aataatatag ccaatcccga taaaaacaat tacattcctg aaaatggcaa tgtctttttt
    19621 atcaataaca attttctgaa tttctataaa aatataaatc atgattttaa aatgattgac
    19681 aatcattcgg ataaaataaa cgtgtttatt cctccaaggt tacaatatca aaaatctgaa
    19741 attcaaaaaa atcaccaagg atggattgac tttcaaaagc aacaaaacaa aaaagtagat
    19801 gtgcaagtac tgtcaaaaaa cgtatctgtt ttttcttttg atcgcacaac taatttgaaa
    19861 tttgggtatc tagattctcc aatagtaatg ttgttgacac ttgacgattt aacaggagat
    19921 ttttatttag ctgctgtttc tcaaggtgga tatctattta aagatttaga tacacttaaa
    19981 cagttgctta aagataatca cctagaagaa gaaattagcg gtataactaa ttacaaggat
    20041 tctgtgttaa atgaattaaa tgaaacgaaa acaaaaatga taataacaat agttactatt
    20101 attattaacg ttttcattct tttgatagct actgtatttg aaacaattca atattttagc
    20161 tggaataaaa agcaactatt attaagaaaa attcatggtt attcattatt cagcagtaat
    20221 gtacgttatt taacaatttc tatcttactt tctattatgt tagcttacac tacgcatatt
    20281 ttatttggtt caaagatatt actattcata ataatgtcta ttgctattat tcaacattta
    20341 cttcaaattg cttatattaa atatcttgaa aaatacttta aagatttaat gagggagatt
    20401 taaacaatga aaagaacttt aattattgta acaattgtac tattaatcat catacttagt
    20461 ctgttattgg ttagaaatga gcatttagat cgttttaacc cactgttaaa agaaaaagta
    20521 tcttatgcca aagttccaaa agatacccag gactatagaa atataactgt atactctaaa
    20581 aatggagaaa aaaagagtta taaattggat tttttaggtt atgatcctac aaaagaatat
    20641 gtgaaagtaa atcataaagg gaaatatgtg cgttcgatag aatacattac aaaagatatt
    20701 cctagctttt taaaatgagg tgaccgatag
//
