LOCUS       NZ_CP022576            13841 bp    DNA     circular CON 25-NOV-2023
DEFINITION  Klebsiella pneumoniae strain BIC-1 plasmid pBIC-1c, complete
            sequence.
ACCESSION   NZ_CP022576
VERSION     NZ_CP022576.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN07419044
            Assembly: GCF_002243445.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 13841)
  AUTHORS   Jousset,A.B., Bonnin,R.A., Rosinski-Chupin,I., Girlich,D., Cuzon,G.,
            Cabanel,N., Frech,H., Farfour,E., Dortet,L., Glaser,P. and Naas,T.
  TITLE     4.5 years within-patient evolution of a colistin resistant
            KPC-producing Klebsiella pneumoniae ST258
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 13841)
  AUTHORS   Jousset,A.B., Bonnin,R.A., Rosinski-Chupin,I., Girlich,D., Cuzon,G.,
            Cabanel,N., Frech,H., Farfour,E., Dortet,L., Glaser,P. and Naas,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-JUL-2017) Hopital de Bicetre, Service de
            bacteriologie, EA7361, Faculte de Medecine, Universite Paris-Sud,
            General Leclerc, Le Kremlin Bicetre 94275, France
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 30-AUG-2016
            Assembly Method                   :: CLC genomic workbench v. 9
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 30.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/25/2023 02:49:47
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,619
            CDSs (total)                      :: 5,494
            Genes (coding)                    :: 5,390
            CDSs (with protein)               :: 5,390
            Genes (RNA)                       :: 125
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 88
            ncRNAs                            :: 12
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 46 of 104
            Pseudo Genes (incomplete)         :: 62 of 104
            Pseudo Genes (internal stop)      :: 11 of 104
            Pseudo Genes (multiple problems)  :: 14 of 104
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP022576.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..13841
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="BIC-1"
                     /host="Homo sapiens"
                     /db_xref="taxon:573"
                     /plasmid="pBIC-1c"
                     /geo_loc_name="France: Kremlin-Bicetre"
                     /collection_date="2009-09-01"
     gene            join(10879..13841,1..43)
                     /locus_tag="CHX41_RS28630"
                     /old_locus_tag="CHX41_28625"
     CDS             join(10879..13841,1..43)
                     /locus_tag="CHX41_RS28630"
                     /old_locus_tag="CHX41_28625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495017.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element Tn3 family transposase"
                     /protein_id="WP_001143775.1"
                     /translation="MPVDFLTTEQVESYGRFTGEPDELQLARYFHLDEADKEFIGKSRG
                     DHNRLGIALQIGCVRFLGTFLTDMNHIPSGVRHFTARQLGIRDITVLAEYGQRENTRRE
                     HAALIRQHYQYREFAWPWTFRLTRLLYTRSWISNERPGLLFDLATGWLMQHRIILPGAT
                     TLTRLISEVREKATLRLWNKLALIPSAEQRSQLEMLLGPTDCSRLSLLESLKKGPVTIS
                     GPAFNEAIERWKTLNDFGLHAENLSTLPAVRLKNLARYAGMTSVFNIARMSPQKRMAVL
                     VAFVLAWETLALDDALDVLDAMLAVIIRDARKIGQKKRLRSLKDLDKSALALASACSYL
                     LKEETPDESIRAEVFSYIPRQKLAEIITLVREIARPSDDNFHDEMVEQYGRVRRFLPHL
                     LNTVKFSSAPAGVTTLNACDYLSREFSSRRQFFDDAPTEIISQSWKRLVINKEKHITRR
                     GYTLCFLSKLQDSLRRRDVYVTGSNRWGDPRARLLQGADWQANRIKVYRSLGHPTDPQE
                     AIKSLGHQLDSRYRQVAARLGENEAVELDVSGPKPRLTISPLASLDEPDSLKRLSKMIS
                     DLLPPVDLTELLLEINAHTGFADEFFHASEASARVDDLPVSISAVLMAEACNIGLEPLI
                     RSNVPALTRHRLNWTKANYLRAETITSANARLVDFQATLPLAQIWGGGEVASADGMRFV
                     TPVRTINAGPNRKYFGNNRGITWYNFVSDQYSGFHGIVIPGTLRDSIFVLEGLLEQETG
                     LNPTEIMTDTAGASDLVFGLFWLLGYQFSPRLADAGASVFWRMDHDADYGVLNDIARGQ
                     SDPRKIVLQWDEMIRTAGSLKLGKVQASVLVRSLLKSERPSGLTQAIIEVGRINKTLYL
                     LNYIDDEDYRRRILTQLNRGESRHAVARAICHGQKGEIRKRYTDGQEDQLGALGLVTNA
                     VVLWNTIYMQAALDHLRAQGETLNDEDIARLSPLCHGHINMLGHYSFTLAELVTKGHLR
                     PLKEASEAENVA"
                     /name="Tn3-like element Tn3 family transposase"
     gene            <78..368
                     /locus_tag="CHX41_RS28635"
                     /old_locus_tag="CHX41_28630"
                     /pseudo=""
     CDS             <78..368
                     /locus_tag="CHX41_RS28635"
                     /old_locus_tag="CHX41_28630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247941.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Exc2 family lipoprotein"
                     /name="Exc2 family lipoprotein"
     gene            674..937
                     /locus_tag="CHX41_RS28640"
                     /old_locus_tag="CHX41_28635"
     CDS             674..937
                     /locus_tag="CHX41_RS28640"
                     /old_locus_tag="CHX41_28635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000072676.1"
                     /translation="MSNTTHYENANFLRELAESLPRILPEGGPDKAALLQRLANEELAQ
                     AEYEDQVRAKVTAARADTRPGMTTEQLRQRLHGRYQELRDAV"
                     /name="hypothetical protein"
     gene            927..1226
                     /locus_tag="CHX41_RS28645"
                     /old_locus_tag="CHX41_28640"
     CDS             927..1226
                     /locus_tag="CHX41_RS28645"
                     /old_locus_tag="CHX41_28640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146176.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_001146176.1"
                     /translation="MPYDVEWKQGAIEDVTTLFDYIAENSSLWDAQNVTDRVLAAADKL
                     ADFPRLYEVDSRYGEDVRRISLMGQHVLYDVDDQTRKVRVLAVVGQRQNPHIVL"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(1288..1665)
                     /locus_tag="CHX41_RS28650"
                     /old_locus_tag="CHX41_28645"
     CDS             complement(1288..1665)
                     /locus_tag="CHX41_RS28650"
                     /old_locus_tag="CHX41_28645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000312627.1"
                     /translation="MAWVTVRQATELTGKARSSLYRDMAKGRVSYRTEADGGRVVDTSE
                     LIRVYGELRQDETHERDELRLSGETEKMASDALIAEIKALREEVAGLRQEMQSMRLLEH
                     KPETAETPAGTPRRWWPWGKR"
                     /name="hypothetical protein"
     gene            1734..1913
                     /locus_tag="CHX41_RS28655"
                     /old_locus_tag="CHX41_28650"
     CDS             1734..1913
                     /locus_tag="CHX41_RS28655"
                     /old_locus_tag="CHX41_28650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_000165971.1"
                     /translation="MTKQEKTALNMAKFIKEQSLLLLDKLNELDMDTPADMCERLHEDA
                     ETLWQVMRDKLGEE"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            complement(1941..2471)
                     /locus_tag="CHX41_RS28660"
                     /old_locus_tag="CHX41_28655"
     CDS             complement(1941..2471)
                     /locus_tag="CHX41_RS28660"
                     /old_locus_tag="CHX41_28655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008321413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004153058.1"
                     /translation="MALYMVFIEDAEDRNGERCIMPTSEHLEDMVVLAWQTGAYVFCFV
                     DRAQHLAMMKSIGMYDERLNSDEKATYFFTGKNPQWERNKPTGMKLCDYLYRKVERFAI
                     ENGVQVVDAGKCSPEQINAMIDVVSERHGESAVNEKLKAELMREYNSRYFNVPVPELPE
                     DKPARRWWPFGKK"
                     /name="hypothetical protein"
     gene            complement(2478..3209)
                     /locus_tag="CHX41_RS28665"
                     /old_locus_tag="CHX41_28660"
     CDS             complement(2478..3209)
                     /locus_tag="CHX41_RS28665"
                     /old_locus_tag="CHX41_28660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family replication-relaxation protein"
                     /protein_id="WP_004152551.1"
                     /translation="MALELYNVSHAKRQARNAEKTRLTLRWLREELCSTAELVARRLGI
                     AAVQPVYRFLDSLVAKGLLVRTKYPVDGRQVSVWGLTPHGVAFSFDEDEPLADVIPFQP
                     SRVSAAHLPHRLAVQSLRLDMEARGATGWRILHRLSLKGMKVPDALAELDGKTVAFEVE
                     RTVKSRRRYQEVVSGYLFNRKANGIDEIWYICPDRATQVRVQRAILSVDEIVNPQTGEA
                     RKTAELDRERLFACFKFMTTE"
                     /name="MobC family replication-relaxation protein"
     gene            complement(3209..5173)
                     /locus_tag="CHX41_RS28670"
                     /old_locus_tag="CHX41_28665"
     CDS             complement(3209..5173)
                     /locus_tag="CHX41_RS28670"
                     /old_locus_tag="CHX41_28665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004178196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="WP_004178196.1"
                     /translation="MFNTDSLAWKWHIPELARQIYPWVSWLYQEYYGLAGAFLVIGLFF
                     GLAELWAGRMRFVGLSHKERREYADRYKRDNKRPAPFSVLASLDSPGRMVRARRHVWNY
                     AYWLTGAAGLALLGGLVVAVFIESWGETVLRPDLYANADYYLLQPANLFGIAWCAGGLA
                     VGIVLARLLAFLLLDGHFAAADEAVNAKLNQESRRSSQRTGEMTDVRHLHFGEPVPVNA
                     LADFSSEQARQEQAVFLGKDEQGKPVLVPRDTWRKTNIQILGLPGSGKSVMATNALIRC
                     VRDFGDAVVYFDPKGDAWAPHVFRAHCPDFTLLDLRPGKPAQLNLFRDLDQYALKNLLI
                     AGLNLGETGDVADHYRISEQKAAKLIAEQFPQGANIQQVLAAAYALPEALKKDVKGLIT
                     RLENVADLSVLQTDSGIDVAGIINGGGCLYVIGSMDDEAVIRVQKMLFARCAQIIIARD
                     EFREWPHVSVMLDEIKYLLSKYVLNALGTLRSRDCNLLLAHQSLGDFGQCGQDLPAEFV
                     KTTVLDNTPIRWFYRAASLESAQWAAGQTGEIRVDVERRRASREAGNVEHISGDSFIQK
                     EARPLFDVNTLQHLPDGFAVMTGLGVARMAFSSPLRVERREIPLQRFPVLAKTDPLAEF
                     RPPADGGGPKADDDFAGIY"
                     /name="TraM recognition domain-containing protein"
     gene            complement(6654..6803)
                     /locus_tag="CHX41_RS28680"
                     /old_locus_tag="CHX41_28675"
     CDS             complement(6654..6803)
                     /locus_tag="CHX41_RS28680"
                     /old_locus_tag="CHX41_28675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891188.1"
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="WP_004152552.1"
                     /translation="MKKVKVVFLFILIFSGFLLVACQANYIRDVQGGTVAPSSSSELTG
                     IAVQ"
                     /name="colicin release lysis protein"
     gene            complement(6888..7145)
                     /locus_tag="CHX41_RS28685"
                     /old_locus_tag="CHX41_28680"
     CDS             complement(6888..7145)
                     /locus_tag="CHX41_RS28685"
                     /old_locus_tag="CHX41_28680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cloacin immunity family protein"
                     /protein_id="WP_004152553.1"
                     /translation="MGLKLHIHWFDKKTEEFKGGEYSKDFGDDGSVIESLGMPLKDNIN
                     NGWFDVEKSWVSILQPHFKNVIDISKFDYFVSFVYRDGNW"
                     /name="cloacin immunity family protein"
     gene            complement(7155..7976)
                     /locus_tag="CHX41_RS28690"
                     /old_locus_tag="CHX41_28685"
     CDS             complement(7155..7976)
                     /locus_tag="CHX41_RS28690"
                     /old_locus_tag="CHX41_28685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004199321.1"
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]; GO:0043022 - ribosome binding
                     [Evidence IEA]; GO:0003723 - RNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin E3/pyocin S6 family cytotoxin"
                     /protein_id="WP_004199321.1"
                     /translation="MSFRSTERQTPTPAQVKQRLEEEKRRQQAWDAAHPEEGLKREYDK
                     AKAELDAEDKNIATLNSRIASTEKAIPGARAAVQEADKKVKEAEANKDDFVTYNPPHEY
                     GSGWQDQVRYLDKDIQNQNEKLKAAQTSLNEMNESLSRDKAALSGAMESRKQKEKKAKD
                     AENKLNEEKKKPRKGTKDYGHDYFPDPKTEDIKGLGELKEGKPKTPKQGGGGKRARWYG
                     DKKRKIYEWDSQHGELEGYRASDGEHLGAFDPKTGKQVKGPDPKRNIKKYL"
                     /name="colicin E3/pyocin S6 family cytotoxin"
     gene            complement(8092..>8262)
                     /locus_tag="CHX41_RS28695"
                     /old_locus_tag="CHX41_28690"
                     /pseudo=""
     CDS             complement(8092..>8262)
                     /locus_tag="CHX41_RS28695"
                     /old_locus_tag="CHX41_28690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489893.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /name="serine hydrolase"
     gene            complement(8317..9021)
                     /locus_tag="CHX41_RS28705"
                     /old_locus_tag="CHX41_28700"
     CDS             complement(8317..9021)
                     /locus_tag="CHX41_RS28705"
                     /old_locus_tag="CHX41_28700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_001067855.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            complement(<9087..9302)
                     /locus_tag="CHX41_RS28710"
                     /old_locus_tag="CHX41_28705"
                     /pseudo=""
     CDS             complement(<9087..9302)
                     /locus_tag="CHX41_RS28710"
                     /old_locus_tag="CHX41_28705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001424636.1"
                     /GO_function="GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing protein"
                     /name="nucleotidyltransferase domain-containing protein"
     gene            complement(9372..9926)
                     /gene="aac(6')-Ib"
                     /locus_tag="CHX41_RS28715"
                     /old_locus_tag="CHX41_28710"
     ARG             complement(9376..9926)
                     /name="aac(6')-Ib"
                     /gene="aac(6')-Ib"
                     /gene_name="AAC(6')-Ib family aminoglycoside
                     6'-N-acetyltransferase"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(10160..10717)
                     /locus_tag="CHX41_RS28720"
                     /old_locus_tag="CHX41_28715"
     CDS             complement(10160..10717)
                     /locus_tag="CHX41_RS28720"
                     /old_locus_tag="CHX41_28715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221001.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001217881.1"
                     /translation="MRIFGYARVSTSQQSLDIQIRALKDAGVKANRIFTDKASGSSTDR
                     EGLDLLRMKVEEGDVILVKKLDRLGRDTADMIQLIKEFDAQGVAVRFIDDGISTDGDMG
                     QMVVTILSAVAQAERRRILERTNEGRQEAKLKGIKFGRRRTVDRNVVLTLHQKGTGATE
                     IAHQLSIARSTVYKILEDERAS"
                     /name="recombinase family protein"
     ARG             complement(9034..9290)
                     /name="aadA15"
                     /gene="aadA15"
                     /gene_name="ANT(3'')"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="97.14"
                     /coverage="32.32"
     ARG             complement(9373..9977)
                     /name="AAC(6')-Ib10"
                     /gene="AAC(6')-Ib10"
                     /gene_name="AAC(6')"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="98.97"
                     /coverage="99.01"
     Typing          5973..6551
                     /name="ColRNAI_rep_cluster_1857"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="95.361"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(2482..3209)
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="1.34e-150"
ORIGIN
        1 gagaccatta aaagaggcgt cagaggcaga aaacgttgct taacgtgagt tttcgttcca
       61 ctgagcgtca gacccctttt gatcccaatt tttccaccca gaaagctgac acaacacgaa
      121 tgatggtgcc ttttttccgg cagttctggg atatgggcgc aaaggataaa gcgaccggaa
      181 aatcacggag tgatgtgcag caacgcattc agcagtttca cagtcaggaa tttttaaact
      241 cactccaagg cacaacacaa tttgcgggta ccgattaccg cagcaaagac ctcacaccga
      301 aaaaatcaag gctactggct gacaccattt cagctgttta tctcgatggc tatgaaggca
      361 gacagtaagt ggatttacca taacgcgtca ttacgcgcac cgctcagacg ggctcagggc
      421 gtttccggcg gctacgggat aaaacaggca acaacccccc cggaaaactg ccggaaacgc
      481 gcccgataaa ttttatccta atgcatgcct atgcacgcaa ctgcatggca tatgttttga
      541 cgtaaaatgg atgccgtaag ccctttttta ccgactttct gcttcatcag cctgactgac
      601 acgaccatat tctttcagac cgccccctgc taaacttcct tcatattgcc gcattaaccc
      661 gggaggctcc gcaatgagca acactacaca ctacgaaaac gccaactttc ttcgggaact
      721 ggctgaaagc ctgccccgca tactgccgga aggtggcccg gacaaagctg cgctgttgca
      781 gcgactggct aacgaagaac tggcccaggc agagtatgaa gatcaggttc gcgccaaagt
      841 gaccgccgcc cgtgctgaca cgcgtccggg tatgaccacg gaacaactcc gccagcgcct
      901 gcatggccgt tatcaggaac tgcgcgatgc cgtatgacgt ggaatggaag cagggagcca
      961 tcgaggatgt aacgacgctg tttgactata tcgcggaaaa ttcatccctg tgggatgcgc
     1021 agaacgttac cgaccgggtt ctcgctgcgg cggacaaact ggccgacttc ccgcgactct
     1081 atgaagtgga ctcacgctat ggcgaggacg ttcgccggat cagtctgatg ggacagcatg
     1141 tcctctatga tgttgatgac cagaccagaa aagtccgggt tctggccgtg gtcggccagc
     1201 gccagaatcc ccatattgtt ctctaataac cggtgacggg gacgcaattc attgcgtggc
     1261 cgtcgccggt tggacaagca cagcgcgtca gcgttttccc cacggccacc accggcgcgg
     1321 tgttccggcc ggggtctctg ctgtctccgg tttgtgttcc agcagtctca tggactgcat
     1381 ttcctgccgt agcccggcca cctcctccct gagtgctttt atctccgcga tcaacgcgtc
     1441 ggaggccatt ttttcagtct cacccgacag tctcaactcg tcccgctcgt gagtctcatc
     1501 ctgtcttaac tcaccgtaca cccggataag ctcgctggta tccaccaccc ggccgccatc
     1561 agcttccgta cggtatgata cgcggccttt cgccatatcc cgatacaggg aacttcgggc
     1621 tttacccgtc agttccgtcg cctgtctcac cgtcacccac gccattgtct caccccgcta
     1681 tttttgagac agtatacctg acaggcgcac accatgcccg gaaggaaaga atcatgacaa
     1741 aacaggaaaa aacagccctc aatatggcta aatttattaa ggagcagtcg ctgctattgc
     1801 tcgataaact gaatgagctg gatatggata ccccggccga catgtgcgag cggctacacg
     1861 aggatgcgga aacactctgg caggtgatgc gggataagct cggggaggaa taacagcacc
     1921 ggcatggccg gtgctggcat ttattttttg ccgaacggcc accaccggcg ggcaggtttg
     1981 tcctccggca gttcaggtac cggcacgtta aaatagcggc tgttatattc ccgcatcagc
     2041 tccgctttca gcttctcgtt caccgcgctt tccccgtgcc gctcactcac cacgtcaatc
     2101 atcgcgttaa tctgctccgg tgagcacttc ccggcatcaa ccacctgcac accgttctcg
     2161 atggcgaacc gctccacctt gcgatagagg taatcacaca gcttcattcc tgtgggtttg
     2221 ttccgttccc attgcggatt tttaccagtg aaaaagtacg tggctttttc gtcgctgttg
     2281 agccgctcgt catacatccc gatggatttc atcatcgcca gatgctgggc ccggtcgaca
     2341 aaacagaaaa catacgcccc ggtctgccag gcgagcacca ccatatcttc cagatgctcg
     2401 ctggtcggca tgatgcagcg ctcgccgttc cggtcctccg cgtcttcaat aaataccatg
     2461 tacagcgcca taatccctca ctccgttgtc ataaatttaa agcacgcaaa caaccgttca
     2521 cgatccagct ctgccgtttt gcgggcctcg ccggtctgtg ggttcacgat ttcatccacc
     2581 gacaggattg cccgctgcac cctgacctgc gtcgcccggt ccgggcagat gtaccagatt
     2641 tcatcgatgc cgttagcttt gcggttgaac agatacccgg acaccacttc ctgataccgg
     2701 cgacggctct tgacggtgcg ctccacctca aacgccaccg ttttaccgtc cagctccgcc
     2761 agggcgtccg gcactttcat gcctttaaga ctcagacggt gcagaatgcg ccagccggtg
     2821 gcccctctgg cttccatatc aaggcgcagg gattgcacgg ccagccggtg cggcagatgt
     2881 gctgccgaca cccttgacgg ctgaaacgga ataacatccg ccagcggttc gtcctcgtcg
     2941 aacgagaacg ccacgccatg cggcgtcagc ccccacacgc tgacctgacg gccgtccacc
     3001 ggatatttgg tccggaccag cagccctttc gccaccaggc tgtcgaggaa gcggtagacc
     3061 ggctgcaccg ccgcaatccc cagccgccgc gcaaccagct ccgccgtgga acacagctct
     3121 tcccgcaacc agcgcagggt cagccgggtt ttctccgcgt tccgcgcctg tcgtttcgcg
     3181 tggctgacgt tgtacagctc cagcgccatc agtaaatccc cgcaaaatca tcatccgctt
     3241 tcggcccgcc gccgtcggcc gggggccgga actccgccag gggatcggtt ttcgccagca
     3301 ccgggaaacg ctgcaacggg atttcccggc gctcaacccg cagcggactg ctgaacgcca
     3361 tccgggccac acccagcccg gtcatgaccg cgaacccgtc cggcaggtgt tgcagggtgt
     3421 tcacgtcaaa cagcggccgc gcctccttct ggatgaagct gtccccgctg atatgctcca
     3481 cgttccccgc ctcccggctg gcacggcggc gctccacgtc caccctgatt tccccggtct
     3541 gccccgccgc ccactgcgcg gactccaggc tggccgcccg gtaaaaccag cggatcggcg
     3601 tgttatccag taccgtggtt ttcacaaatt cagcgggcag atcctgcccg cactgcccga
     3661 aatcgcccag cgactggtgc gcgagcaaca gattgcagtc ccggctgcgc agcgtcccca
     3721 gtgcgttcag tacatacttc gacagcagat atttaatttc atcgagcatc acgctgacgt
     3781 gtggccactc ccggaactcg tcccgcgcaa tgatgatttg cgcgcagcgg gcaaacagca
     3841 ttttttgcac acggatcacc gcctcgtcgt ccatcgagcc gataacgtac aggcagccgc
     3901 cgccgttgat aatccccgcc acatcgatgc cactgtccgt ctgcaggacg ctcaggtcag
     3961 cgacgttttc cagcctagtg atcaacccct tcacgtcctt tttcagggcc tccggcagcg
     4021 cgtacgccgc cgccagcacc tgctgaatgt ttgccccctg cggaaactgc tccgcaatca
     4081 gcttcgccgc tttctgctcg ctgatgcggt agtggtccgc cacgtcgccg gtctcgccca
     4141 ggttaagccc ggcaatcagc aggtttttca gcgcgtactg gtcgagatcg cggaacagat
     4201 tcagctgcgc cggtttcccc ggccgcagat ccagcagggt gaagtccgga cagtgcgccc
     4261 ggaagacgtg cggcgcccat gcgtcccctt tggggtcgaa gtacaccacc gcgtccccga
     4321 aatcgcgtac gcagcgaatg agcgcgttgg tggccatcac gctcttgccg ctcccgggca
     4381 ggccgaggat ctgaatgttg gtcttgcgcc aggtatcacg cggaaccagc accggcttgc
     4441 cctgctcatc cttacccaga aacaccgcct gctcctgccg ggcctgctcc gaggaaaaat
     4501 cggccagcgc attaaccggt accggctccc cgaaatgcag gtggcgcacg tcggtcatct
     4561 ctcctgtccg ctggctgctg cgccggctct cctgattcag tttcgcgttc accgcctcgt
     4621 cagcagccgc aaaatgaccg tcaagcagca ggaacgccag cagccgcgcc aacacaatcc
     4681 cgacagccag cccgcccgcg caccaggcaa tcccgaacag gttagccggc tgcagcaggt
     4741 aataatctgc gtttgcgtag aggtccggac gcaggacggt ttctccccag ctctcgataa
     4801 acacggcgac aaccagcccc cccagaaggg ccagaccggc cgcgccggtc agccagtacg
     4861 cgtagttcca gacatgtcga cgtgccctga ccatccgccc gggcgaatcc agcgaggcca
     4921 gcaccgaaaa tggcgctggc cgtttattat cgcgcttata gcgatcggca tactcccgtc
     4981 gctccttatg actcagcccc acaaaacgca tccgtccggc ccaaagttca gccagaccga
     5041 aaaacaggcc gataactagg aaagccccgg ccagaccgta atactcctgg tacagccagc
     5101 tgacccacgg ataaatctgc cgggccagct ccggaatgtg ccacttccag gcaagcgaat
     5161 ccgtattaaa catgttctct ctccttcaga cgatggtttg ccggcgtgat gtgcagcccc
     5221 cgctgcacaa gccgcggaca tgccccaagg catggcggcg gcggtcacgt ccgtggtgat
     5281 tgcgttcagc tttcaccacg gaggccagcc tctttccgcc ccatgcggaa aaggcgcagc
     5341 cccggaggaa caacgagcac gccccagcgt gtgagaggaa aaggcggcac cccagtgcgg
     5401 tcttttccgg tgttccggcc cccgtcagag ttcgccatag cgagcggctg accacccgca
     5461 aaatcaggag cagctttgct gcttcgccag gtgcgtccag caccgtggat ttttgtgggt
     5521 ggtcaggcgt gagcctgacg ggggccgggt gaatttctgg cgtggccggc gtccagccgg
     5581 acggagccag aaagaggggg agagaccgtg cgtcggtggc gtccagccag cgtaagcagg
     5641 ggatatcccc ctgaggtcag ccacgccctc gcggggatga cctgtatttc tccgtaagga
     5701 gaaaaaagca acagagatag gttaacgtaa aatgttcagc gaaaaaccga tatgattcac
     5761 ctatcctggt aatttattat cagggaatat aaagacttaa tcaggggaca atatgccaca
     5821 tcagcgcgtc cggtgtccgt cttgtaggtg ccggggaaat tgcgcctcct cgctcactcg
     5881 gtcgctacgc tccggccgtg agactgcggc gggcgctgcg gacacatgca aagttaccca
     5941 cagattccgt gaataagcag gggactaaca tgtgaggcaa aacggcaagg ccacgcaggt
     6001 ggcgtttttc cataggctcc gccctcctga ctgagttcac ataaacagac gctttttcgg
     6061 tgcatctgtg ggagccggtg gctcaaccat gaatcagtca ggagtggcga aacccgacag
     6121 gacttaaaga tcatcaccgt ttccgatgaa tcgctccctc ttgcgctctc ctgttccaac
     6181 cctgccgttt cccggatacc tgttccgcct ttctcccttg cgggaagtgt ggcgctttct
     6241 catagctcac actctggtat ctcggctcgg tgtaggtcgt tcgctccaag ctgggctgta
     6301 agcaagaacc ccccgttcag cccgactgct gcgccttatc cggtaactgt tcacttgagt
     6361 ccaacccgga aaagcacgca aaacgccact ggcagcagcc attggtaact gggagttcgc
     6421 agaggatttg tttagctaaa cacgcggttg ctcttgaagt gtgcgccaaa gtccggctac
     6481 actggaagga cagatttggt tgctgtgctc tgcgaaagcc agttaccacg gttaagcagt
     6541 tccccaactg acttaacctt cgatcaaacc acctccccag gtggtttttt cgtttacagg
     6601 gcaaaagatt acgcgcagaa aaaaaggatc tcaagaagat cctttgatct tttctactga
     6661 accgcgatcc ccgtcagttc agaggaggac gatggtgcca ccgttccacc ctgaacatcc
     6721 cggatatagt ttgcctgaca tgcgaccaga agaaagcctg aaaaaatcaa tataaaaaga
     6781 aaaacaacct ttaccttttt catatacctt ccctgtattt aaaaaccccg gtattcatcc
     6841 ctgaacaccg gaagtctgta tttcaaatca tccttgataa cttttgctta ccagttacca
     6901 tcccggtaaa caaaggatac aaagtaatca aatttactaa tatcgattac atttttaaag
     6961 tgtggctgta atatcgaaac ccatgatttt tcaacatcaa accaaccatt attaatatta
     7021 tcctttaaag gcatccccag actttcaatg acagaaccat catcaccgaa gtcttttgag
     7081 tattcaccac ctttaaactc ttcggttttc ttatcaaacc aatgaatatg taatttaagc
     7141 cccatattta cctcttaaag atatttttta atgtttcgtt ttggatccgg ccctttaacc
     7201 tgcttacccg tttttggatc gaatgccccg aggtgttcgc catcactggc gcggtaccct
     7261 tcaagctcac cgtgctggga atcccattca taaattttac gctttttatc accataccat
     7321 cgggcccgct taccaccacc accttgttta ggggttttag gtttaccctc tttcaactct
     7381 cccaacccct taatatcttc agtcttggga tcaggaaaat aatcatggcc gtaatcttta
     7441 gttcccttac gaggtttttt cttttcctca tttaatttat tttctgcatc cttcgctttt
     7501 ttctcctttt gtttccggct ctccatcgcc ccggaaagcg cagccttatc cctggataag
     7561 gattcattca tttcgtttaa agatgtctgg gcagctttta atttctcatt ctgattctga
     7621 atatccttat caagatagcg aacctgatcc tgccacccgg agccatattc atgaggcggg
     7681 ttataagtca caaaatcatc tttatttgcc tctgcctctt ttaccttttt atcggcttcc
     7741 tgaacagcag cccttgcacc ggggatcgcc ttctctgtcg atgcaatgcg actgtttaag
     7801 gtcgcaatat ttttatcttc agcatccagc tcagctttcg ctttatcata ctctcttttc
     7861 agcccctctt ccgggtgagc agcgtcccat gcctgctggc gacgcttttc ttcctccaga
     7921 cgctgtttta cctgtgccgg agtaggggtc tgacgctcag tggaacgaaa actcacgtta
     7981 agggattttg gtcatgagat tatcaaaaag gatcttcacc tagatccttt taaattaaaa
     8041 atgaagtttt aaatcaatct aaagtatata tgagtaaact tggtctgaca gttaccaatg
     8101 cttaatcagt gaggcaccta tctcagcgat ctgtctattt cgttcatcca tagttgcctg
     8161 actccccgtc gtgtagataa ctacgatacg ggagggctta ccatctggcc ccagtgctgc
     8221 aatgataccg cgagacccac gctcaccggc tccagattta tcagggcact gttgcaaagt
     8281 tagcgatgag gcagcctttt gtcttattca aaggccttac atttcaaaaa ctctgcttac
     8341 caggcgcatt tcgcccaggg gatcaccata ataaaatgct gaggcctggc ctttgcgtag
     8401 tgcacgcatc acctcaatac ctttgatggt ggcgtaagcc gtcttcatgg atttaaatcc
     8461 cagcgtggcg ccgattatcc gtttcagttt gccatgatcg cattcaatca cgttgttccg
     8521 gtacttaatc tgtcggtgtt caacgtcaga cgggcaccgg ccttcgcgtt tgagcagagc
     8581 aagcgcgcga ccataggcgg gcgctttatc cgtgttgatg aatcgcggga tctgccactt
     8641 cttcacgttg ttgaggattt tacccagaaa ccggtatgca gctttgctgt tacgacggga
     8701 ggagagataa aaatcgacag tgcggccccg gctgtcgacg gcccggtaca gatacgccca
     8761 gcggccattg accttcacgt aggtttcatc catgtgccac gggcaaagat cggaagggtt
     8821 acgccagtac cagcgcagcc gtttttccat ttcaggcgca taacgctgaa cccagcggta
     8881 aatcgtggag tgatcgacat tcactccgcg ttcagccagc atctcctgca gctcacggta
     8941 actgatgccg tatttgcagt accagcgtac ggcccacaga atgatgtcac gctgaaaatg
     9001 ccggcctttg aatgggttca tgtgcagctc catcagcaaa aggggatgat aagtttatca
     9061 ccaccgacta tttgcaacag tgccgtttcc aaaaggtcgt tgatcaaagc tcgccgcgtt
     9121 gtttcatcaa gccttacggt caccgtaacc agcaaatcaa tatcactgtg tggcttcagg
     9181 ccgccatcca ctgcggagcc gtacaaatgt acggccagca acgtcggttc gagatggcgc
     9241 tcgatgacgc caactacctc tgatagttga gtcgatactt cggcgatcac cgcttccctc
     9301 atgatgttta acgtttgaca tgaggggcgg ccaagggcgc cagcccttgg acgtccccct
     9361 cgatggaagg gttaggcaac actgcgtgtt cgctcgaatg cctggcgtgt ttgaaccatg
     9421 tacacggctg gaccatctgg ggtggttacg gtaccttgcc tctcaaaccc cgctttctcg
     9481 tagcatcgga tcgctcgcaa gttgctcggc gacgggtccg tttggatctt ggtgacctcg
     9541 ggatcattga acagcaactc aaccagagct cgaaccagct tggttcccaa gcctttgccc
     9601 agttgtgatg cattcgccag taactggtct attccgcgta ctcctggatc ggtttcttct
     9661 tcccaccatc cgtccccgct tccaagagca acgtacgact gggcataccc aatcggctct
     9721 ccattcagca ttgcaatgta tggagtgacg gactcttgcg ctaaaacgct tggcaagtac
     9781 tgttcctgta cgtcagcaag tgtcgggcgt gcttcttctc cgccccacca ctcgacgata
     9841 tgagatcgat ttagccactc atagagcatc gcaaggtcat gctcagtcat gaggcgcagt
     9901 gtgacggaat cgttgctgtt ggtcacgatg ctgtactttg tgatgcctaa ctttgtttgg
     9961 aaatgttgaa tactcatact cttccttttt caatattatt gaagcattta tcagggttat
    10021 tgtctcatga gcggatacat atttgaatgt atttagaaaa ataaacaaat aggggttccg
    10081 cgcacatttc cccgaaaagt gccacctgac gtctaagaaa ccattattat catgacatta
    10141 acctataaaa ataggcgtat cacgaggccc tttcgtcttc aagaatttta taaaccgtgg
    10201 agcgggcaat actgagctga tgagcaattt ccgttgcacc agtgcccttc tgatgaagcg
    10261 tcagcacgac gttcctgtcc acggtacgcc tgcggccaaa tttgattcct ttcagctttg
    10321 cttcctgtcg gccctcattc gtgcgctcta ggatcctccg gcgttcagcc tgtgccacag
    10381 ccgacaggat ggtgaccacc atttgcccca tatcaccgtc ggtactgatc ccgtcgtcaa
    10441 taaaccgaac cgctacaccc tgagcatcaa actcttttat cagttggatc atgtcggcgg
    10501 tgtcgcggcc aagacggtcg agcttcttca ccagaatgac atcaccttcc tccaccttca
    10561 tcctcagcaa atccagccct tcccgatctg ttgaactgcc ggatgccttg tcggtaaaga
    10621 tgcggttagc ttttacccct gcatctttga gcgctctgat ctgaatatcg agggactgct
    10681 ggctggttga gacccgcgca taaccaaaaa ttcgcataaa aatgtacctt aaatcgaata
    10741 tcagacacga tgtgtctatt atgccaaaat gacgatttaa tggacactca aacgaagccg
    10801 ttttactatg tctgataatt tataatattt cgaacggttg cagttgtgtt aaaaaagccg
    10861 tcaggcaggg aggccgatat gcccgttgat tttttgacca ctgagcaggt tgagagttat
    10921 ggcaggttca ctggcgaacc cgatgaactt cagctggcgc gttattttca tcttgatgaa
    10981 gcggataaag aatttatcgg gaaaagccgg ggtgatcaca atcgacttgg tattgccctg
    11041 caaatcgggt gtgtgcgttt tctgggcact tttcttactg acatgaatca tattccttcc
    11101 ggcgtccggc attttaccgc cagacagctc gggattcgtg atatcaccgt tcttgcagaa
    11161 tacggtcaga gggaaaatac ccgccgtgag catgcagcgc tgatacgtca gcactatcag
    11221 tatcgtgaat ttgcctggcc ctggacattt cgccttaccc gtcttttata tacccggagc
    11281 tggataagca acgaacgtcc tggcctgctt ttcgacctgg cgacagggtg gcttatgcaa
    11341 catcgtatta ttctccccgg agccaccacg ctgacccggt tgatttcaga ggtaagggaa
    11401 aaggcgacgt tgcgcctgtg gaacaaactg gcactgatac cgtcagccga acagcgttca
    11461 cagctggaga tgctgctggg gccaactgat tgcagccgcc tgtctttact ggaatcactg
    11521 aaaaaaggcc ctgtgaccat cagtggtccg gcgtttaatg aagcaattga acgctggaaa
    11581 actctgaacg attttggcct gcatgctgaa aacctgagta cactcccggc tgtgcgcctg
    11641 aaaaatctcg cacgttatgc tggtatgact tcggtgttca atattgccag gatgtcaccg
    11701 cagaaaagga tggcggttct ggttgccttt gtccttgcat gggaaacgct ggcgctggat
    11761 gatgcactgg acgttctgga cgccatgctg gccgttatca tccgtgacgc cagaaagatt
    11821 gggcagaaaa aacggctccg ctcgctgaag gatctggata aatctgcatt ggcgctcgcc
    11881 agcgcatgtt cgtacttgct gaaagaagaa acaccggacg aatcgattcg tgctgaggtg
    11941 ttcagctaca tccctaggca aaagctggct gaaatcatca cgcttgtccg tgaaattgcc
    12001 cggccctcag acgataattt tcatgacgaa atggtggagc agtacgggcg cgttcgtcgt
    12061 ttcctgcccc atctgctgaa taccgttaaa ttttcatccg cacctgccgg ggttaccact
    12121 ctgaatgcct gtgactacct cagccgggag ttcagctcac ggcggcagtt ttttgacgac
    12181 gcaccaacgg aaatcatcag tcagtcatgg aaacggctgg tgattaacaa ggaaaaacat
    12241 atcacccgaa ggggatacac gctctgcttt ctcagtaaac tgcaggatag tctgagacgg
    12301 agggatgtct acgttaccgg cagtaaccgg tggggagatc ctcgtgcaag attactacag
    12361 ggtgctgact ggcaggcaaa tcggattaag gtttatcgtt ctttggggca cccgacagac
    12421 ccgcaggaag caataaaatc tctgggccat cagcttgata gtcgttacag acaggttgct
    12481 gcacgtcttg gcgaaaatga ggctgtcgaa ctcgatgttt ctggcccgaa gccccggttg
    12541 acaatttctc ccctcgccag tcttgatgag ccggacagtc tgaaacgact gagcaaaatg
    12601 atcagtgatc tgctccctcc ggtggattta acggagttgc tgctcgaaat taacgcccat
    12661 accggatttg ctgatgagtt tttccatgcc agtgaagcca gtgccagagt tgatgatctg
    12721 cccgtcagca tcagcgccgt gctgatggct gaagcctgca atatcggtct ggaaccactg
    12781 atcagatcaa atgttcctgc actgacccga caccggctga actggacaaa agcgaactat
    12841 ctgcgggctg aaactatcac cagcgctaat gccagactgg ttgattttca ggcaacgctg
    12901 ccactggcac agatatgggg tggaggagaa gtggcatctg cagatggaat gcgctttgtt
    12961 acgccagtca gaacaatcaa tgccggaccg aaccgcaaat actttggtaa taacagaggg
    13021 atcacctggt acaactttgt gtccgatcag tattccggct ttcatggcat cgttataccg
    13081 gggacgctga gggactctat ctttgtgctg gaaggccttc tggaacagga gaccgggctg
    13141 aatccaaccg aaattatgac cgatacggca ggtgccagcg atcttgtctt tggccttttc
    13201 tggctgctgg gataccagtt ttctccacgc ctggctgatg ccggtgcttc ggttttctgg
    13261 cgaatggacc atgatgccga ctatggcgtg ctgaatgata ttgccagagg gcaatcagat
    13321 ccccgaaaaa tagtccttca gtgggacgaa atgatccgga ccgcaggctc cctgaagctg
    13381 ggcaaagtac aggcctcagt gctggtccgt tcattgctga aaagtgaacg tccctccgga
    13441 ctgactcagg caatcattga agtggggcgc atcaacaaaa cgctgtatct gcttaattat
    13501 attgatgatg aagattaccg ccggcgcatt ctgacccagc ttaatcgggg agaaagccgt
    13561 catgcagttg ccagagccat ctgtcacggt caaaaaggtg agataagaaa acgatatacc
    13621 gacggtcagg aagatcagtt gggagctctg gggctggtca ctaacgccgt cgtgttatgg
    13681 aacactattt atatgcaggc agctctggat catctccggg cgcagggtga aacactgaat
    13741 gatgaagata tcgcacgcct ctccccgctt tgccacggac atatcaatat gctcggccat
    13801 tattccttca cgctggcaga actggtgacc aaaggtcatc t
//
