LOCUS       NZ_CP018431            18890 bp    DNA     circular CON 26-DEC-2023
DEFINITION  Klebsiella pneumoniae strain MNCRE78 plasmid pMNCRE78_1, complete
            sequence.
ACCESSION   NZ_CP018431
VERSION     NZ_CP018431.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN06067846
            Assembly: GCF_001902195.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 18890)
  AUTHORS   Johnson,T.J., Hargreaves,M., Lynfield,R. and Snippes-Vignone,P.
  TITLE     Clonal dissemination of KPC-2 ST258 Klebsiella pneumoniae in
            Minnesota
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 18890)
  AUTHORS   Johnson,T.J., Hargreaves,M., Lynfield,R. and Snippes-Vignone,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-NOV-2016) Veterinary and Biomedical Sciences,
            University of Minnesota, 1971 Commonwealth Ave, 205 Veterinary
            Science, St Paul, MN 55108, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: PacBio SMRT Portal v. Nov-2016; Pilon
            Genome Coverage                   :: 100x; 20x
            Sequencing Technology             :: PacBio RS II; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 12/26/2023 01:48:41
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,761
            CDSs (total)                      :: 5,638
            Genes (coding)                    :: 5,497
            CDSs (with protein)               :: 5,497
            Genes (RNA)                       :: 123
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 87
            ncRNAs                            :: 11
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 60 of 141
            Pseudo Genes (incomplete)         :: 86 of 141
            Pseudo Genes (internal stop)      :: 17 of 141
            Pseudo Genes (multiple problems)  :: 18 of 141
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP018431.1.
            Source bacteria is available from Paula Snippes through the
            Minnesota Department of Health.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..18890
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="MNCRE78"
                     /isolation_source="Wound"
                     /host="Homo sapiens"
                     /db_xref="taxon:573"
                     /plasmid="pMNCRE78_1"
                     /geo_loc_name="USA:Minnesota"
                     /lat_lon="46.7296 N 94.6859 W"
                     /collection_date="2013-01"
                     /collected_by="Minnesota Department of Health"
     gene            47..750
                     /locus_tag="BTE52_RS30260"
                     /pseudo=""
     CDS             47..750
                     /locus_tag="BTE52_RS30260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006770492.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /name="IS6 family transposase"
     gene            <805..975
                     /locus_tag="BTE52_RS30270"
                     /old_locus_tag="BTE52_30040"
                     /pseudo=""
     CDS             <805..975
                     /locus_tag="BTE52_RS30270"
                     /old_locus_tag="BTE52_30040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489893.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /name="serine hydrolase"
     gene            1772..3169
                     /locus_tag="BTE52_RS33515"
                     /old_locus_tag="BTE52_30050"
     CDS             1772..3169
                     /locus_tag="BTE52_RS33515"
                     /old_locus_tag="BTE52_30050"
                     /inference="COORDINATES: protein motif:HMM:NF015479.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin-like bacteriocin tRNase domain-containing
                     protein"
                     /protein_id="WP_004152554.1"
                     /translation="MAFGLPALATPGAEGLALSVSGDALSAAVADVLAALKGPFKFGLW
                     GIAIYGVLPSEIAKDDPKMMSKIVTSLPADTVTETPVSSLPLDQATVSVTKRVADIVKD
                     ERQHIAVVTGRPMSVPVVDAKPTKRPGVFSVSIPGLPSLQVSVPKGVPAAKAPPKGIIA
                     EKGDSRPAGFTAGGNSREAVIRFPKESGQKPVYVSVTDVLTPAQVKQRLEEEKRRQQAW
                     DAAHPEEGLKREYDKAKAELDAEDKNIATLNSRIASTEKAIPGARAAVQEADKKVKEAE
                     ANKDDFVTYNPPHEYGSGWQDQVRYLDKDIQNQNEKLKAAQTSLNEMNESLSRDKAALS
                     GAMESRKQKEKKAKDAENKLNEEKKKPRKGTKDYGHDYFPDPKTEDIKGLGELKEGKPK
                     TPKQGGGGKRARWYGDKKRKIYEWDSQHGELEGYRASDGEHLGAFDPKTGKQVKGPDPK
                     RNIKKYL"
                     /name="colicin-like bacteriocin tRNase domain-containing
                     protein"
     gene            3179..3436
                     /locus_tag="BTE52_RS30285"
                     /old_locus_tag="BTE52_30055"
     CDS             3179..3436
                     /locus_tag="BTE52_RS30285"
                     /old_locus_tag="BTE52_30055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cloacin immunity family protein"
                     /protein_id="WP_004152553.1"
                     /translation="MGLKLHIHWFDKKTEEFKGGEYSKDFGDDGSVIESLGMPLKDNIN
                     NGWFDVEKSWVSILQPHFKNVIDISKFDYFVSFVYRDGNW"
                     /name="cloacin immunity family protein"
     gene            3521..3670
                     /locus_tag="BTE52_RS30290"
                     /old_locus_tag="BTE52_30060"
     CDS             3521..3670
                     /locus_tag="BTE52_RS30290"
                     /old_locus_tag="BTE52_30060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891188.1"
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="WP_004152552.1"
                     /translation="MKKVKVVFLFILIFSGFLLVACQANYIRDVQGGTVAPSSSSELTG
                     IAVQ"
                     /name="colicin release lysis protein"
     gene            5151..7115
                     /locus_tag="BTE52_RS30300"
                     /old_locus_tag="BTE52_30070"
     CDS             5151..7115
                     /locus_tag="BTE52_RS30300"
                     /old_locus_tag="BTE52_30070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004178196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="WP_004178196.1"
                     /translation="MFNTDSLAWKWHIPELARQIYPWVSWLYQEYYGLAGAFLVIGLFF
                     GLAELWAGRMRFVGLSHKERREYADRYKRDNKRPAPFSVLASLDSPGRMVRARRHVWNY
                     AYWLTGAAGLALLGGLVVAVFIESWGETVLRPDLYANADYYLLQPANLFGIAWCAGGLA
                     VGIVLARLLAFLLLDGHFAAADEAVNAKLNQESRRSSQRTGEMTDVRHLHFGEPVPVNA
                     LADFSSEQARQEQAVFLGKDEQGKPVLVPRDTWRKTNIQILGLPGSGKSVMATNALIRC
                     VRDFGDAVVYFDPKGDAWAPHVFRAHCPDFTLLDLRPGKPAQLNLFRDLDQYALKNLLI
                     AGLNLGETGDVADHYRISEQKAAKLIAEQFPQGANIQQVLAAAYALPEALKKDVKGLIT
                     RLENVADLSVLQTDSGIDVAGIINGGGCLYVIGSMDDEAVIRVQKMLFARCAQIIIARD
                     EFREWPHVSVMLDEIKYLLSKYVLNALGTLRSRDCNLLLAHQSLGDFGQCGQDLPAEFV
                     KTTVLDNTPIRWFYRAASLESAQWAAGQTGEIRVDVERRRASREAGNVEHISGDSFIQK
                     EARPLFDVNTLQHLPDGFAVMTGLGVARMAFSSPLRVERREIPLQRFPVLAKTDPLAEF
                     RPPADGGGPKADDDFAGIY"
                     /name="TraM recognition domain-containing protein"
     gene            7115..7846
                     /locus_tag="BTE52_RS30305"
                     /old_locus_tag="BTE52_30075"
     CDS             7115..7846
                     /locus_tag="BTE52_RS30305"
                     /old_locus_tag="BTE52_30075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family replication-relaxation protein"
                     /protein_id="WP_004152551.1"
                     /translation="MALELYNVSHAKRQARNAEKTRLTLRWLREELCSTAELVARRLGI
                     AAVQPVYRFLDSLVAKGLLVRTKYPVDGRQVSVWGLTPHGVAFSFDEDEPLADVIPFQP
                     SRVSAAHLPHRLAVQSLRLDMEARGATGWRILHRLSLKGMKVPDALAELDGKTVAFEVE
                     RTVKSRRRYQEVVSGYLFNRKANGIDEIWYICPDRATQVRVQRAILSVDEIVNPQTGEA
                     RKTAELDRERLFACFKFMTTE"
                     /name="MobC family replication-relaxation protein"
     gene            7853..8383
                     /locus_tag="BTE52_RS30310"
                     /old_locus_tag="BTE52_30080"
     CDS             7853..8383
                     /locus_tag="BTE52_RS30310"
                     /old_locus_tag="BTE52_30080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008321413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004153058.1"
                     /translation="MALYMVFIEDAEDRNGERCIMPTSEHLEDMVVLAWQTGAYVFCFV
                     DRAQHLAMMKSIGMYDERLNSDEKATYFFTGKNPQWERNKPTGMKLCDYLYRKVERFAI
                     ENGVQVVDAGKCSPEQINAMIDVVSERHGESAVNEKLKAELMREYNSRYFNVPVPELPE
                     DKPARRWWPFGKK"
                     /name="hypothetical protein"
     gene            complement(8411..8590)
                     /locus_tag="BTE52_RS30315"
                     /old_locus_tag="BTE52_30085"
     CDS             complement(8411..8590)
                     /locus_tag="BTE52_RS30315"
                     /old_locus_tag="BTE52_30085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_000165971.1"
                     /translation="MTKQEKTALNMAKFIKEQSLLLLDKLNELDMDTPADMCERLHEDA
                     ETLWQVMRDKLGEE"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            8659..9036
                     /locus_tag="BTE52_RS30320"
                     /old_locus_tag="BTE52_30090"
     CDS             8659..9036
                     /locus_tag="BTE52_RS30320"
                     /old_locus_tag="BTE52_30090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000312627.1"
                     /translation="MAWVTVRQATELTGKARSSLYRDMAKGRVSYRTEADGGRVVDTSE
                     LIRVYGELRQDETHERDELRLSGETEKMASDALIAEIKALREEVAGLRQEMQSMRLLEH
                     KPETAETPAGTPRRWWPWGKR"
                     /name="hypothetical protein"
     gene            complement(9098..9397)
                     /locus_tag="BTE52_RS30325"
                     /old_locus_tag="BTE52_30095"
     CDS             complement(9098..9397)
                     /locus_tag="BTE52_RS30325"
                     /old_locus_tag="BTE52_30095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146176.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_001146176.1"
                     /translation="MPYDVEWKQGAIEDVTTLFDYIAENSSLWDAQNVTDRVLAAADKL
                     ADFPRLYEVDSRYGEDVRRISLMGQHVLYDVDDQTRKVRVLAVVGQRQNPHIVL"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(9387..9650)
                     /locus_tag="BTE52_RS30330"
                     /old_locus_tag="BTE52_30100"
     CDS             complement(9387..9650)
                     /locus_tag="BTE52_RS30330"
                     /old_locus_tag="BTE52_30100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000072676.1"
                     /translation="MSNTTHYENANFLRELAESLPRILPEGGPDKAALLQRLANEELAQ
                     AEYEDQVRAKVTAARADTRPGMTTEQLRQRLHGRYQELRDAV"
                     /name="hypothetical protein"
     gene            complement(9956..10375)
                     /locus_tag="BTE52_RS30335"
                     /old_locus_tag="BTE52_30105"
     CDS             complement(9956..10375)
                     /locus_tag="BTE52_RS30335"
                     /old_locus_tag="BTE52_30105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Exc2 family lipoprotein"
                     /protein_id="WP_001254601.1"
                     /translation="MRRSGSKLCLIAMITATATLTACAPKGSVEQHTRHYVYASDDGFD
                     PNFSTQKADTTRMMVPFFRQFWDMGAKDKATGKSRSDVQQRIQQFHSQEFLNSLQGTTQ
                     FAGTDYRSKDLTPKKSRLLADTISAVYLDGYEGRQ"
                     /name="Exc2 family lipoprotein"
     gene            complement(10452..13457)
                     /locus_tag="BTE52_RS30340"
                     /old_locus_tag="BTE52_30110"
     CDS             complement(10452..13457)
                     /locus_tag="BTE52_RS30340"
                     /old_locus_tag="BTE52_30110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495017.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element Tn3 family transposase"
                     /protein_id="WP_001143775.1"
                     /translation="MPVDFLTTEQVESYGRFTGEPDELQLARYFHLDEADKEFIGKSRG
                     DHNRLGIALQIGCVRFLGTFLTDMNHIPSGVRHFTARQLGIRDITVLAEYGQRENTRRE
                     HAALIRQHYQYREFAWPWTFRLTRLLYTRSWISNERPGLLFDLATGWLMQHRIILPGAT
                     TLTRLISEVREKATLRLWNKLALIPSAEQRSQLEMLLGPTDCSRLSLLESLKKGPVTIS
                     GPAFNEAIERWKTLNDFGLHAENLSTLPAVRLKNLARYAGMTSVFNIARMSPQKRMAVL
                     VAFVLAWETLALDDALDVLDAMLAVIIRDARKIGQKKRLRSLKDLDKSALALASACSYL
                     LKEETPDESIRAEVFSYIPRQKLAEIITLVREIARPSDDNFHDEMVEQYGRVRRFLPHL
                     LNTVKFSSAPAGVTTLNACDYLSREFSSRRQFFDDAPTEIISQSWKRLVINKEKHITRR
                     GYTLCFLSKLQDSLRRRDVYVTGSNRWGDPRARLLQGADWQANRIKVYRSLGHPTDPQE
                     AIKSLGHQLDSRYRQVAARLGENEAVELDVSGPKPRLTISPLASLDEPDSLKRLSKMIS
                     DLLPPVDLTELLLEINAHTGFADEFFHASEASARVDDLPVSISAVLMAEACNIGLEPLI
                     RSNVPALTRHRLNWTKANYLRAETITSANARLVDFQATLPLAQIWGGGEVASADGMRFV
                     TPVRTINAGPNRKYFGNNRGITWYNFVSDQYSGFHGIVIPGTLRDSIFVLEGLLEQETG
                     LNPTEIMTDTAGASDLVFGLFWLLGYQFSPRLADAGASVFWRMDHDADYGVLNDIARGQ
                     SDPRKIVLQWDEMIRTAGSLKLGKVQASVLVRSLLKSERPSGLTQAIIEVGRINKTLYL
                     LNYIDDEDYRRRILTQLNRGESRHAVARAICHGQKGEIRKRYTDGQEDQLGALGLVTNA
                     VVLWNTIYMQAALDHLRAQGETLNDEDIARLSPLCHGHINMLGHYSFTLAELVTKGHLR
                     PLKEASEAENVA"
                     /name="Tn3-like element Tn3 family transposase"
     gene            13619..14176
                     /locus_tag="BTE52_RS30345"
                     /old_locus_tag="BTE52_30115"
     CDS             13619..14176
                     /locus_tag="BTE52_RS30345"
                     /old_locus_tag="BTE52_30115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221001.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001217881.1"
                     /translation="MRIFGYARVSTSQQSLDIQIRALKDAGVKANRIFTDKASGSSTDR
                     EGLDLLRMKVEEGDVILVKKLDRLGRDTADMIQLIKEFDAQGVAVRFIDDGISTDGDMG
                     QMVVTILSAVAQAERRRILERTNEGRQEAKLKGIKFGRRRTVDRNVVLTLHQKGTGATE
                     IAHQLSIARSTVYKILEDERAS"
                     /name="recombinase family protein"
     gene            14410..14964
                     /gene="aac(6')-Ib"
                     /locus_tag="BTE52_RS30350"
                     /old_locus_tag="BTE52_30120"
     ARG             14411..14961
                     /name="aac(6')-Ib"
                     /gene="aac(6')-Ib"
                     /gene_name="AAC(6')-Ib family aminoglycoside
                     6'-N-acetyltransferase"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            15034..>15249
                     /locus_tag="BTE52_RS30355"
                     /old_locus_tag="BTE52_30125"
                     /pseudo=""
     CDS             15034..>15249
                     /locus_tag="BTE52_RS30355"
                     /old_locus_tag="BTE52_30125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001424636.1"
                     /GO_function="GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing protein"
                     /name="nucleotidyltransferase domain-containing protein"
     gene            15315..16019
                     /locus_tag="BTE52_RS30360"
                     /old_locus_tag="BTE52_30130"
     CDS             15315..16019
                     /locus_tag="BTE52_RS30360"
                     /old_locus_tag="BTE52_30130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_001067855.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            <16074..16244
                     /locus_tag="BTE52_RS30370"
                     /old_locus_tag="BTE52_30140"
                     /pseudo=""
     CDS             <16074..16244
                     /locus_tag="BTE52_RS30370"
                     /old_locus_tag="BTE52_30140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489893.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /name="serine hydrolase"
     gene            16755..18445
                     /locus_tag="BTE52_RS30380"
                     /old_locus_tag="BTE52_30150"
                     /pseudo=""
     CDS             16755..18445
                     /locus_tag="BTE52_RS30380"
                     /old_locus_tag="BTE52_30150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891190.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="colicin-like bacteriocin tRNase domain-containing
                     protein"
                     /name="colicin-like bacteriocin tRNase domain-containing
                     protein"
     gene            18465..18702
                     /locus_tag="BTE52_RS30385"
                     /old_locus_tag="BTE52_30155"
                     /pseudo=""
     CDS             18465..18702
                     /locus_tag="BTE52_RS30385"
                     /old_locus_tag="BTE52_30155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891189.1"
                     /GO_function="GO:0015643 - toxic substance binding
                     [Evidence IEA]"
                     /GO_process="GO:0030153 - bacteriocin immunity [Evidence
                     IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="colicin E3-like toxin immunity protein"
                     /name="colicin E3-like toxin immunity protein"
     ARG             15047..15303
                     /name="aadA15"
                     /gene="aadA15"
                     /gene_name="ANT(3'')"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="97.14"
                     /coverage="32.32"
     ARG             14360..14964
                     /name="AAC(6')-Ib10"
                     /gene="AAC(6')-Ib10"
                     /gene_name="AAC(6')"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="98.97"
                     /coverage="99.01"
     BGC             1..18890
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          complement(3774..4352)
                     /name="ColRNAI_rep_cluster_1857"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="95.361"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          7116..7843
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="1.35e-150"
ORIGIN
        1 tcggtggtga taaacttatc atcccctttt gctgatggag ctgcacatga acccattcaa
       61 aggccggcat ttcagcgtga catcattctg tgggccgtac gctggtactg caaatacggc
      121 atcagttacc gtgagctgca ggagatgctg gctgaacgcg gagtgaatgt cgatcactcc
      181 acgatttacc gctgggttca gcgttatgcg cctgaaatgg aaaaacggct gcgctggtac
      241 tggcgtaacc cttccgatct ttgcccgtgg cacatggatg aaacctacgt gaaggtcaat
      301 ggccgctggg cgtatctgta ccgggccgtc gacagccggg gccgcactgt cgatttttat
      361 ctctcctccc gtcgtaacag caaagctgca taccggtttc tgggtaaaat cctcaaacaa
      421 cgtgaagaag tggcagatcc cgcgattcat caacacggat aaagcgccgc ctatggtcgc
      481 gcgcttgctc tgctcaaacg cgaaggccgg tgcccgtctg acgttgaaca ccgacagatt
      541 aagtaccgga acaacgtgat tgaatgcgat catggcaaac tgaaacggat aatcggcgcc
      601 acgctgggat ttaaatccat gaagacggct tacgccacca tcaaaggtat tgaggtgatg
      661 cgtgcactac gcaaaggcca ggcctcagca ttttattatg gtgatcccct gggcgaaatg
      721 cgcctggtaa gcagagtttt tgaaatgtaa ggcctttgaa taagacaaaa ggctgcctca
      781 tcgctaactt tgcaacagtg ccctgataaa tctggagccg gtgagcgtgg gtctcgcggt
      841 atcattgcag cactggggcc agatggtaag ccctcccgta tcgtagttat ctacacgacg
      901 gggagtcagg caactatgga tgaacgaaat agacagatcg ctgagatagg tgcctcactg
      961 attaagcatt ggtaactgtc agaccaagtt tactcatata tactttagat tgatttaaaa
     1021 cttcattttt aatttaaaag gatctaggtg aagatccttt ttgataatct catgaccaaa
     1081 atcccttaac gtgagttttc gttccactga gcgtcagacc ccttatatat ccgcaggcta
     1141 tcttatcatc agtttctgac cgtgttcagt gaccgaacaa cccgaaccag acccccgttt
     1201 cttttcctgt cccggagggg gctttctggt atcttcatat aatgatttca gtaaaacata
     1261 ctgaggccgg agaacggcgc cgtttgtgct ggtttttgtt gcatctggag ggattgcgca
     1321 tggtgtgagt ggctgttttt ttgatcattt tcacaaaacg caaatttaca gacttgacat
     1381 gaaaaacaag gcagcgtaat ttttatactg tatataaaac cagtggttat atgtacagta
     1441 ttttatttta gtttattgtt ttaaaagtca aagaggaaaa gtatatgagt ggcggagacg
     1501 gacgaggtcc gggtaattca ggtctgggac acaatggtgg tcaggccagt gggaatgtga
     1561 acggtacatc aggtaaaggt ggcccttcat caggtggtgg tacggatcca aacagcgggc
     1621 cgggctgggg tacgacgcat acacctaacg gggatattca taactataac ccgggggagt
     1681 ttggtaacgg cggagtaaac ccggtggtaa tggcggtaac agcggcaatc atagcgggag
     1741 ctctggtggc ggacagtctt cggccaccgc gatggccttc ggtctgcctg ccttggccac
     1801 tccgggggct gaaggactgg ctttatccgt ttccggcgat gcgttgtcgg ccgctgttgc
     1861 tgatgtgctg gctgccctga aaggtccgtt taagtttggt ctgtggggga ttgcgattta
     1921 cggagtgctg ccttctgaga tagcaaaaga tgatccgaaa atgatgtcaa aaatcgtgac
     1981 gtcattgccg gcagacacgg taacggagac gccggtcagc tccctgccgc tggaccaggc
     2041 gacggtcagc gtcactaaac gtgtggcgga tattgtgaag gacgagcggc agcatattgc
     2101 ggttgtcacc ggccggccaa tgagtgttcc tgtggtggat gcgaaaccga caaaacgtcc
     2161 gggggtattc agtgtgtcga ttccgggtct cccgtctctg caggtgagcg tacctaaagg
     2221 tgttccggcc gcgaaagccc cgccaaaagg cattattgct gaaaaaggtg attcacgtcc
     2281 ggctggtttt acggccggtg gtaactcccg tgaagccgtt attcgtttcc cgaaagagag
     2341 cggacagaaa ccggtctatg tgtcggtgac ggatgttctt actccggcac aggtaaaaca
     2401 gcgtctggag gaagaaaagc gtcgccagca ggcatgggac gctgctcacc cggaagaggg
     2461 gctgaaaaga gagtatgata aagcgaaagc tgagctggat gctgaagata aaaatattgc
     2521 gaccttaaac agtcgcattg catcgacaga gaaggcgatc cccggtgcaa gggctgctgt
     2581 tcaggaagcc gataaaaagg taaaagaggc agaggcaaat aaagatgatt ttgtgactta
     2641 taacccgcct catgaatatg gctccgggtg gcaggatcag gttcgctatc ttgataagga
     2701 tattcagaat cagaatgaga aattaaaagc tgcccagaca tctttaaacg aaatgaatga
     2761 atccttatcc agggataagg ctgcgctttc cggggcgatg gagagccgga aacaaaagga
     2821 gaaaaaagcg aaggatgcag aaaataaatt aaatgaggaa aagaaaaaac ctcgtaaggg
     2881 aactaaagat tacggccatg attattttcc tgatcccaag actgaagata ttaaggggtt
     2941 gggagagttg aaagagggta aacctaaaac ccctaaacaa ggtggtggtg gtaagcgggc
     3001 ccgatggtat ggtgataaaa agcgtaaaat ttatgaatgg gattcccagc acggtgagct
     3061 tgaagggtac cgcgccagtg atggcgaaca cctcggggca ttcgatccaa aaacgggtaa
     3121 gcaggttaaa gggccggatc caaaacgaaa cattaaaaaa tatctttaag aggtaaatat
     3181 ggggcttaaa ttacatattc attggtttga taagaaaacc gaagagttta aaggtggtga
     3241 atactcaaaa gacttcggtg atgatggttc tgtcattgaa agtctgggga tgcctttaaa
     3301 ggataatatt aataatggtt ggtttgatgt tgaaaaatca tgggtttcga tattacagcc
     3361 acactttaaa aatgtaatcg atattagtaa atttgattac tttgtatcct ttgtttaccg
     3421 ggatggtaac tggtaagcaa aagttatcaa ggatgatttg aaatacagac ttccggtgtt
     3481 cagggatgaa taccggggtt tttaaataca gggaaggtat atgaaaaagg taaaggttgt
     3541 ttttcttttt atattgattt tttcaggctt tcttctggtc gcatgtcagg caaactatat
     3601 ccgggatgtt cagggtggaa cggtggcacc atcgtcctcc tctgaactga cggggatcgc
     3661 ggttcagtag aaaagatcaa aggatcttct tgagatcctt tttttctgcg cgtaatcttt
     3721 tgccctgtaa acgaaaaaac cacctgggga ggtggtttga tcgaaggtta agtcagttgg
     3781 ggaactgctt aaccgtggta actggctttc gcagagcaca gcaaccaaat ctgtccttcc
     3841 agtgtagccg gactttggcg cacacttcaa gagcaaccgc gtgtttagct aaacaaatcc
     3901 tctgcgaact cccagttacc aatggctgct gccagtggcg ttttgcgtgc ttttccgggt
     3961 tggactcaag tgaacagtta ccggataagg cgcagcagtc gggctgaacg gggggttctt
     4021 gcttacagcc cagcttggag cgaacgacct acaccgagcc gagataccag agtgtgagct
     4081 atgagaaagc gccacacttc ccgcaaggga gaaaggcgga acaggtatcc gggaaacggc
     4141 agggttggaa caggagagcg caagagggag cgattcatcg gaaacggtga tgatctttaa
     4201 gtcctgtcgg gtttcgccac tcctgactga ttcatggttg agccaccggc tcccacagat
     4261 gcaccgaaaa agcgtctgtt tatgtgaact cagtcaggag ggcggagcct atggaaaaac
     4321 gccacctgcg tggccttgcc gttttgcctc acatgttagt cccctgctta ttcacggaat
     4381 ctgtgggtaa ctttgcatgt gtccgcagcg cccgccgcag tctcacggcc ggagcgtagc
     4441 gaccgagtga gcgaggaggc gcaatttccc cggcacctac aagacggaca ccggacgcgc
     4501 tgatgtggca tattgtcccc tgattaagtc tttatattcc ctgataataa attaccagga
     4561 taggtgaatc atatcggttt ttcgctgaac attttacgtt aacctatctc tgttgctttt
     4621 ttctccttac ggagaaatac aggtcatccc cgcgagggcg tggctgacct cagggggata
     4681 tcccctgctt acgctggctg gacgccaccg acgcacggtc tctccccctc tttctggctc
     4741 cgtccggctg gacgccggcc acgccagaaa ttcacccggc ccccgtcagg ctcacgcctg
     4801 accacccaca aaaatccacg gtgctggacg cacctggcga agcagcaaag ctgctcctga
     4861 ttttgcgggt ggtcagccgc tcgctatggc gaactctgac gggggccgga acaccggaaa
     4921 agaccgcact ggggtgccgc cttttcctct cacacgctgg ggcgtgctcg ttgttcctcc
     4981 ggggctgcgc cttttccgca tggggcggaa agaggctggc ctccgtggtg aaagctgaac
     5041 gcaatcacca cggacgtgac cgccgccgcc atgccttggg gcatgtccgc ggcttgtgca
     5101 gcgggggctg cacatcacgc cggcaaacca tcgtctgaag gagagagaac atgtttaata
     5161 cggattcgct tgcctggaag tggcacattc cggagctggc ccggcagatt tatccgtggg
     5221 tcagctggct gtaccaggag tattacggtc tggccggggc tttcctagtt atcggcctgt
     5281 ttttcggtct ggctgaactt tgggccggac ggatgcgttt tgtggggctg agtcataagg
     5341 agcgacggga gtatgccgat cgctataagc gcgataataa acggccagcg ccattttcgg
     5401 tgctggcctc gctggattcg cccgggcgga tggtcagggc acgtcgacat gtctggaact
     5461 acgcgtactg gctgaccggc gcggccggtc tggcccttct gggggggctg gttgtcgccg
     5521 tgtttatcga gagctgggga gaaaccgtcc tgcgtccgga cctctacgca aacgcagatt
     5581 attacctgct gcagccggct aacctgttcg ggattgcctg gtgcgcgggc gggctggctg
     5641 tcgggattgt gttggcgcgg ctgctggcgt tcctgctgct tgacggtcat tttgcggctg
     5701 ctgacgaggc ggtgaacgcg aaactgaatc aggagagccg gcgcagcagc cagcggacag
     5761 gagagatgac cgacgtgcgc cacctgcatt tcggggagcc ggtaccggtt aatgcgctgg
     5821 ccgatttttc ctcggagcag gcccggcagg agcaggcggt gtttctgggt aaggatgagc
     5881 agggcaagcc ggtgctggtt ccgcgtgata cctggcgcaa gaccaacatt cagatcctcg
     5941 gcctgcccgg gagcggcaag agcgtgatgg ccaccaacgc gctcattcgc tgcgtacgcg
     6001 atttcgggga cgcggtggtg tacttcgacc ccaaagggga cgcatgggcg ccgcacgtct
     6061 tccgggcgca ctgtccggac ttcaccctgc tggatctgcg gccggggaaa ccggcgcagc
     6121 tgaatctgtt ccgcgatctc gaccagtacg cgctgaaaaa cctgctgatt gccgggctta
     6181 acctgggcga gaccggcgac gtggcggacc actaccgcat cagcgagcag aaagcggcga
     6241 agctgattgc ggagcagttt ccgcaggggg caaacattca gcaggtgctg gcggcggcgt
     6301 acgcgctgcc ggaggccctg aaaaaggacg tgaaggggtt gatcactagg ctggaaaacg
     6361 tcgctgacct gagcgtcctg cagacggaca gtggcatcga tgtggcgggg attatcaacg
     6421 gcggcggctg cctgtacgtt atcggctcga tggacgacga ggcggtgatc cgtgtgcaaa
     6481 aaatgctgtt tgcccgctgc gcgcaaatca tcattgcgcg ggacgagttc cgggagtggc
     6541 cacacgtcag cgtgatgctc gatgaaatta aatatctgct gtcgaagtat gtactgaacg
     6601 cactggggac gctgcgcagc cgggactgca atctgttgct cgcgcaccag tcgctgggcg
     6661 atttcgggca gtgcgggcag gatctgcccg ctgaatttgt gaaaaccacg gtactggata
     6721 acacgccgat ccgctggttt taccgggcgg ccagcctgga gtccgcgcag tgggcggcgg
     6781 ggcagaccgg ggaaatcagg gtggacgtgg agcgccgccg tgccagccgg gaggcgggga
     6841 acgtggagca tatcagcggg gacagcttca tccagaagga ggcgcggccg ctgtttgacg
     6901 tgaacaccct gcaacacctg ccggacgggt tcgcggtcat gaccgggctg ggtgtggccc
     6961 ggatggcgtt cagcagtccg ctgcgggttg agcgccggga aatcccgttg cagcgtttcc
     7021 cggtgctggc gaaaaccgat cccctggcgg agttccggcc cccggccgac ggcggcgggc
     7081 cgaaagcgga tgatgatttt gcggggattt actgatggcg ctggagctgt acaacgtcag
     7141 ccacgcgaaa cgacaggcgc ggaacgcgga gaaaacccgg ctgaccctgc gctggttgcg
     7201 ggaagagctg tgttccacgg cggagctggt tgcgcggcgg ctggggattg cggcggtgca
     7261 gccggtctac cgcttcctcg acagcctggt ggcgaaaggg ctgctggtcc ggaccaaata
     7321 tccggtggac ggccgtcagg tcagcgtgtg ggggctgacg ccgcatggcg tggcgttctc
     7381 gttcgacgag gacgaaccgc tggcggatgt tattccgttt cagccgtcaa gggtgtcggc
     7441 agcacatctg ccgcaccggc tggccgtgca atccctgcgc cttgatatgg aagccagagg
     7501 ggccaccggc tggcgcattc tgcaccgtct gagtcttaaa ggcatgaaag tgccggacgc
     7561 cctggcggag ctggacggta aaacggtggc gtttgaggtg gagcgcaccg tcaagagccg
     7621 tcgccggtat caggaagtgg tgtccgggta tctgttcaac cgcaaagcta acggcatcga
     7681 tgaaatctgg tacatctgcc cggaccgggc gacgcaggtc agggtgcagc gggcaatcct
     7741 gtcggtggat gaaatcgtga acccacagac cggcgaggcc cgcaaaacgg cagagctgga
     7801 tcgtgaacgg ttgtttgcgt gctttaaatt tatgacaacg gagtgaggga ttatggcgct
     7861 gtacatggta tttattgaag acgcggagga ccggaacggc gagcgctgca tcatgccgac
     7921 cagcgagcat ctggaagata tggtggtgct cgcctggcag accggggcgt atgttttctg
     7981 ttttgtcgac cgggcccagc atctggcgat gatgaaatcc atcgggatgt atgacgagcg
     8041 gctcaacagc gacgaaaaag ccacgtactt tttcactggt aaaaatccgc aatgggaacg
     8101 gaacaaaccc acaggaatga agctgtgtga ttacctctat cgcaaggtgg agcggttcgc
     8161 catcgagaac ggtgtgcagg tggttgatgc cgggaagtgc tcaccggagc agattaacgc
     8221 gatgattgac gtggtgagtg agcggcacgg ggaaagcgcg gtgaacgaga agctgaaagc
     8281 ggagctgatg cgggaatata acagccgcta ttttaacgtg ccggtacctg aactgccgga
     8341 ggacaaacct gcccgccggt ggtggccgtt cggcaaaaaa taaatgccag caccggccat
     8401 gccggtgctg ttattcctcc ccgagcttat cccgcatcac ctgccagagt gtttccgcat
     8461 cctcgtgtag ccgctcgcac atgtcggccg gggtatccat atccagctca ttcagtttat
     8521 cgagcaatag cagcgactgc tccttaataa atttagccat attgagggct gttttttcct
     8581 gttttgtcat gattctttcc ttccgggcat ggtgtgcgcc tgtcaggtat actgtctcaa
     8641 aaatagcggg gtgagacaat ggcgtgggtg acggtgagac aggcgacgga actgacgggt
     8701 aaagcccgaa gttccctgta tcgggatatg gcgaaaggcc gcgtatcata ccgtacggaa
     8761 gctgatggcg gccgggtggt ggataccagc gagcttatcc gggtgtacgg tgagttaaga
     8821 caggatgaga ctcacgagcg ggacgagttg agactgtcgg gtgagactga aaaaatggcc
     8881 tccgacgcgt tgatcgcgga gataaaagca ctcagggagg aggtggccgg gctacggcag
     8941 gaaatgcagt ccatgagact gctggaacac aaaccggaga cagcagagac cccggccgga
     9001 acaccgcgcc ggtggtggcc gtggggaaaa cgctgacgcg ctgtgcttgt ccaaccggcg
     9061 acggccacgc aatgaattgc gtccccgtca ccggttatta gagaacaata tggggattct
     9121 ggcgctggcc gaccacggcc agaacccgga cttttctggt ctggtcatca acatcataga
     9181 ggacatgctg tcccatcaga ctgatccggc gaacgtcctc gccatagcgt gagtccactt
     9241 catagagtcg cgggaagtcg gccagtttgt ccgccgcagc gagaacccgg tcggtaacgt
     9301 tctgcgcatc ccacagggat gaattttccg cgatatagtc aaacagcgtc gttacatcct
     9361 cgatggctcc ctgcttccat tccacgtcat acggcatcgc gcagttcctg ataacggcca
     9421 tgcaggcgct ggcggagttg ttccgtggtc atacccggac gcgtgtcagc acgggcggcg
     9481 gtcactttgg cgcgaacctg atcttcatac tctgcctggg ccagttcttc gttagccagt
     9541 cgctgcaaca gcgcagcttt gtccgggcca ccttccggca gtatgcgggg caggctttca
     9601 gccagttccc gaagaaagtt ggcgttttcg tagtgtgtag tgttgctcat tgcggagcct
     9661 cccgggttaa tgcggcaata tgaaggaagt ttagcagggg gcggtctgaa agaatatggt
     9721 cgtgtcagtc aggctgatga agcagaaagt cggtaaaaaa gggcttacgg catccatttt
     9781 acgtcaaaac atatgccatg cagttgcgtg cataggcatg cattaggata aaatttatcg
     9841 ggcgcgtttc cggcagtttt ccgggggggt tgttgcctgt tttatcccgt agccgccgga
     9901 aacgccctga gcccgtctga gcggtgcgcg taatgacgcg ttatggtaaa tccacttact
     9961 gtctgccttc atagccatcg agataaacag ctgaaatggt gtcagccagt agccttgatt
    10021 ttttcggtgt gaggtctttg ctgcggtaat cggtacccgc aaattgtgtt gtgccttgga
    10081 gtgagtttaa aaattcctga ctgtgaaact gctgaatgcg ttgctgcaca tcactccgtg
    10141 attttccggt cgctttatcc tttgcgccca tatcccagaa ctgccggaaa aaaggcacca
    10201 tcattcgtgt tgtgtcagct ttctgggtgg aaaaattggg atcaaaaccg tcatctgaag
    10261 catatacgta atgccgggta tgctgttcca cgctgccctt tggagcacag gcagtgagag
    10321 ttgctgtcgc tgttatcatg gcgataagac acagtttgct gccggaacgt ctcatgagcg
    10381 tctccttacc tttaattctt ttttctcatt gagttatagg ggtctgacgc tcagtggaac
    10441 gaaaactcac gttaagcaac gttttctgcc tctgacgcct cttttaatgg tctcagatga
    10501 cctttggtca ccagttctgc cagcgtgaag gaataatggc cgagcatatt gatatgtccg
    10561 tggcaaagcg gggagaggcg tgcgatatct tcatcattca gtgtttcacc ctgcgcccgg
    10621 agatgatcca gagctgcctg catataaata gtgttccata acacgacggc gttagtgacc
    10681 agccccagag ctcccaactg atcttcctga ccgtcggtat atcgttttct tatctcacct
    10741 ttttgaccgt gacagatggc tctggcaact gcatgacggc tttctccccg attaagctgg
    10801 gtcagaatgc gccggcggta atcttcatca tcaatataat taagcagata cagcgttttg
    10861 ttgatgcgcc ccacttcaat gattgcctga gtcagtccgg agggacgttc acttttcagc
    10921 aatgaacgga ccagcactga ggcctgtact ttgcccagct tcagggagcc tgcggtccgg
    10981 atcatttcgt cccactgaag gactattttt cggggatctg attgccctct ggcaatatca
    11041 ttcagcacgc catagtcggc atcatggtcc attcgccaga aaaccgaagc accggcatca
    11101 gccaggcgtg gagaaaactg gtatcccagc agccagaaaa ggccaaagac aagatcgctg
    11161 gcacctgccg tatcggtcat aatttcggtt ggattcagcc cggtctcctg ttccagaagg
    11221 ccttccagca caaagataga gtccctcagc gtccccggta taacgatgcc atgaaagccg
    11281 gaatactgat cggacacaaa gttgtaccag gtgatccctc tgttattacc aaagtatttg
    11341 cggttcggtc cggcattgat tgttctgact ggcgtaacaa agcgcattcc atctgcagat
    11401 gccacttctc ctccacccca tatctgtgcc agtggcagcg ttgcctgaaa atcaaccagt
    11461 ctggcattag cgctggtgat agtttcagcc cgcagatagt tcgcttttgt ccagttcagc
    11521 cggtgtcggg tcagtgcagg aacatttgat ctgatcagtg gttccagacc gatattgcag
    11581 gcttcagcca tcagcacggc gctgatgctg acgggcagat catcaactct ggcactggct
    11641 tcactggcat ggaaaaactc atcagcaaat ccggtatggg cgttaatttc gagcagcaac
    11701 tccgttaaat ccaccggagg gagcagatca ctgatcattt tgctcagtcg tttcagactg
    11761 tccggctcat caagactggc gaggggagaa attgtcaacc ggggcttcgg gccagaaaca
    11821 tcgagttcga cagcctcatt ttcgccaaga cgtgcagcaa cctgtctgta acgactatca
    11881 agctgatggc ccagagattt tattgcttcc tgcgggtctg tcgggtgccc caaagaacga
    11941 taaaccttaa tccgatttgc ctgccagtca gcaccctgta gtaatcttgc acgaggatct
    12001 ccccaccggt tactgccggt aacgtagaca tccctccgtc tcagactatc ctgcagttta
    12061 ctgagaaagc agagcgtgta tccccttcgg gtgatatgtt tttccttgtt aatcaccagc
    12121 cgtttccatg actgactgat gatttccgtt ggtgcgtcgt caaaaaactg ccgccgtgag
    12181 ctgaactccc ggctgaggta gtcacaggca ttcagagtgg taaccccggc aggtgcggat
    12241 gaaaatttaa cggtattcag cagatggggc aggaaacgac gaacgcgccc gtactgctcc
    12301 accatttcgt catgaaaatt atcgtctgag ggccgggcaa tttcacggac aagcgtgatg
    12361 atttcagcca gcttttgcct agggatgtag ctgaacacct cagcacgaat cgattcgtcc
    12421 ggtgtttctt ctttcagcaa gtacgaacat gcgctggcga gcgccaatgc agatttatcc
    12481 agatccttca gcgagcggag ccgttttttc tgcccaatct ttctggcgtc acggatgata
    12541 acggccagca tggcgtccag aacgtccagt gcatcatcca gcgccagcgt ttcccatgca
    12601 aggacaaagg caaccagaac cgccatcctt ttctgcggtg acatcctggc aatattgaac
    12661 accgaagtca taccagcata acgtgcgaga tttttcaggc gcacagccgg gagtgtactc
    12721 aggttttcag catgcaggcc aaaatcgttc agagttttcc agcgttcaat tgcttcatta
    12781 aacgccggac cactgatggt cacagggcct tttttcagtg attccagtaa agacaggcgg
    12841 ctgcaatcag ttggccccag cagcatctcc agctgtgaac gctgttcggc tgacggtatc
    12901 agtgccagtt tgttccacag gcgcaacgtc gccttttccc ttacctctga aatcaaccgg
    12961 gtcagcgtgg tggctccggg gagaataata cgatgttgca taagccaccc tgtcgccagg
    13021 tcgaaaagca ggccaggacg ttcgttgctt atccagctcc gggtatataa aagacgggta
    13081 aggcgaaatg tccagggcca ggcaaattca cgatactgat agtgctgacg tatcagcgct
    13141 gcatgctcac ggcgggtatt ttccctctga ccgtattctg caagaacggt gatatcacga
    13201 atcccgagct gtctggcggt aaaatgccgg acgccggaag gaatatgatt catgtcagta
    13261 agaaaagtgc ccagaaaacg cacacacccg atttgcaggg caataccaag tcgattgtga
    13321 tcaccccggc ttttcccgat aaattcttta tccgcttcat caagatgaaa ataacgcgcc
    13381 agctgaagtt catcgggttc gccagtgaac ctgccataac tctcaacctg ctcagtggtc
    13441 aaaaaatcaa cgggcatatc ggcctccctg cctgacggct tttttaacac aactgcaacc
    13501 gttcgaaata ttataaatta tcagacatag taaaacggct tcgtttgagt gtccattaaa
    13561 tcgtcatttt ggcataatag acacatcgtg tctgatattc gatttaaggt acatttttat
    13621 gcgaattttt ggttatgcgc gggtctcaac cagccagcag tccctcgata ttcagatcag
    13681 agcgctcaaa gatgcagggg taaaagctaa ccgcatcttt accgacaagg catccggcag
    13741 ttcaacagat cgggaagggc tggatttgct gaggatgaag gtggaggaag gtgatgtcat
    13801 tctggtgaag aagctcgacc gtcttggccg cgacaccgcc gacatgatcc aactgataaa
    13861 agagtttgat gctcagggtg tagcggttcg gtttattgac gacgggatca gtaccgacgg
    13921 tgatatgggg caaatggtgg tcaccatcct gtcggctgtg gcacaggctg aacgccggag
    13981 gatcctagag cgcacgaatg agggccgaca ggaagcaaag ctgaaaggaa tcaaatttgg
    14041 ccgcaggcgt accgtggaca ggaacgtcgt gctgacgctt catcagaagg gcactggtgc
    14101 aacggaaatt gctcatcagc tcagtattgc ccgctccacg gtttataaaa ttcttgaaga
    14161 cgaaagggcc tcgtgatacg cctattttta taggttaatg tcatgataat aatggtttct
    14221 tagacgtcag gtggcacttt tcggggaaaa gtgcgcggaa cccctatttg tttatttttc
    14281 taaatacatt caaatatgta tccgctcatg agacaataac cctgataaat gcttcaataa
    14341 tattgaaaaa ggaagagtat gagtattcaa catttccaaa caaagttagg catcacaaag
    14401 tacagcatcg tgaccaacag caacgattcc gtcacactgc gcctcatgac tgagcatgac
    14461 cttgcgatgc tctatgagtg gctaaatcga tctcatatcg tcgagtggtg gggcggagaa
    14521 gaagcacgcc cgacacttgc tgacgtacag gaacagtact tgccaagcgt tttagcgcaa
    14581 gagtccgtca ctccatacat tgcaatgctg aatggagagc cgattgggta tgcccagtcg
    14641 tacgttgctc ttggaagcgg ggacggatgg tgggaagaag aaaccgatcc aggagtacgc
    14701 ggaatagacc agttactggc gaatgcatca caactgggca aaggcttggg aaccaagctg
    14761 gttcgagctc tggttgagtt gctgttcaat gatcccgagg tcaccaagat ccaaacggac
    14821 ccgtcgccga gcaacttgcg agcgatccga tgctacgaga aagcggggtt tgagaggcaa
    14881 ggtaccgtaa ccaccccaga tggtccagcc gtgtacatgg ttcaaacacg ccaggcattc
    14941 gagcgaacac gcagtgttgc ctaacccttc catcgagggg gacgtccaag ggctggcgcc
    15001 cttggccgcc cctcatgtca aacgttaaac atcatgaggg aagcggtgat cgccgaagta
    15061 tcgactcaac tatcagaggt agttggcgtc atcgagcgcc atctcgaacc gacgttgctg
    15121 gccgtacatt tgtacggctc cgcagtggat ggcggcctga agccacacag tgatattgat
    15181 ttgctggtta cggtgaccgt aaggcttgat gaaacaacgc ggcgagcttt gatcaacgac
    15241 cttttggaaa cggcactgtt gcaaatagtc ggtggtgata aacttatcat ccccttttgc
    15301 tgatggagct gcacatgaac ccattcaaag gccggcattt tcagcgtgac atcattctgt
    15361 gggccgtacg ctggtactgc aaatacggca tcagttaccg tgagctgcag gagatgctgg
    15421 ctgaacgcgg agtgaatgtc gatcactcca cgatttaccg ctgggttcag cgttatgcgc
    15481 ctgaaatgga aaaacggctg cgctggtact ggcgtaaccc ttccgatctt tgcccgtggc
    15541 acatggatga aacctacgtg aaggtcaatg gccgctgggc gtatctgtac cgggccgtcg
    15601 acagccgggg ccgcactgtc gatttttatc tctcctcccg tcgtaacagc aaagctgcat
    15661 accggtttct gggtaaaatc ctcaacaacg tgaagaagtg gcagatcccg cgattcatca
    15721 acacggataa agcgcccgcc tatggtcgcg cgcttgctct gctcaaacgc gaaggccggt
    15781 gcccgtctga cgttgaacac cgacagatta agtaccggaa caacgtgatt gaatgcgatc
    15841 atggcaaact gaaacggata atcggcgcca cgctgggatt taaatccatg aagacggctt
    15901 acgccaccat caaaggtatt gaggtgatgc gtgcactacg caaaggccag gcctcagcat
    15961 tttattatgg tgatcccctg ggcgaaatgc gcctggtaag cagagttttt gaaatgtaag
    16021 gcctttgaat aagacaaaag gctgcctcat cgctaacttt gcaacagtgc cctgataaat
    16081 ctggagccgg tgagcgtggg tctcgcggta tcattgcagc actggggcca gatggtaagc
    16141 cctcccgtat cgtagttatc tacacgacgg ggagtcaggc aactatggat gaacgaaata
    16201 gacagatcgc tgagataggt gcctcactga ttaagcattg gtaactgtca gaccaagttt
    16261 actcatatat actttagatt gatttaaaac ttcattttta atttaaaagg atctaggtga
    16321 agatcctttt tgataatctc atgaccaaaa tcccttaacg tgagttttcg ttccactgag
    16381 cgtcagaccc cttatatatc cgcaggctat cttatcatca gtttctgacc gtgttcagtg
    16441 accgaacaac ccgaaccaga cccccgtttc ttttcctgtc ccggaggggg ctttctggta
    16501 tctcatataa tgatttcagt aaaacatact gaggccggag aacggcgccg tttgtgctgg
    16561 tttttgttgc atctggaggg gattgcgcat ggtgtgagtg gctgtttttt tgatcatttt
    16621 cacaaaaacg caaatttaca gacttgacat gaaaaacaag gcagcgtaat ttttatactg
    16681 tatataaaac cagtggttat atgtacagta ttttatttta gtttattgtt ttaaaagtca
    16741 aagaggaaaa gtatatgagt ggcggagacg gacgaggtcc gggtaattca ggtctgggac
    16801 acaatggtgg tcaggccagt gggaatgtga acggtacatc aggtaaaggt ggcccttcat
    16861 caggtggtgg tacggatcca aacagcgggc cgggctgggg tacgacgcat acacctaacg
    16921 gggatattca taactataac ccgggggagt ttggtaacgg cgggagtaaa cccggtggta
    16981 atggcggtaa cagcggcaat catagcggga gctctggtgg cggacagtct tcggccaccg
    17041 cgatggcctt cggtctgcct gccttggcca ctccgggggc tgaaggactg gctttatccg
    17101 tttccggcga tgcgttgtcg gccgctgttg ctgatgtgct ggctgccctg aaaggtccgt
    17161 ttaagtttgg tctgtggggg attgcgattt acggagtgct gccttctgag atagcaaaag
    17221 atgatccgaa aatgatgtca aaaatcgtga cgtcattgcc ggcagacacg gtaacggaga
    17281 cgccggtcag ctccctgccg ctggaccagg cgacggtcag cgtcactaaa cgtgtggcgg
    17341 atattgtgaa ggacgagcgg cagcatattg cggttgtcac cggccggcca atgagtgttc
    17401 ctgtggtgga tgcgaaaccg acaaaacgtc cgggggtatt cagtgtgtcg attccgggtc
    17461 tcccgtctct gcaggtgagc gtacctaaag gtgttccggc cgcgaaagcc ccgccaaaag
    17521 gcattattgc tgaaaaaggt gattcacgtc cggctggttt tacggccggt ggtaactccc
    17581 gtgaagccgt tattcgtttc ccgaaagaga gcggacagaa accggtctat gtgtcggtga
    17641 cggatgttct tactccggca caggtaaaac agcgtctgga ggaagaaaag cgtcgccagc
    17701 aggcatggga cgctgctcac ccggaagagg ggctgaaaag agagtatgat aaagcgaaag
    17761 ctgagctgga tgctgaagat aaaaatattg cgaccttaaa cagtcgcatt gcatcgacag
    17821 agaaggcgat ccccggtgca agggctgctg ttcaggaagc cgataaaaag gtaaaagagg
    17881 cagaggcaaa taaagatgat tttgtgactt ataacccgcc tcatgaatat ggctccgggt
    17941 ggcaggatca ggttcgctat cttgataagg atattcagaa tcagaatgag aaattaaaag
    18001 ctgcccagac atctttaaac gaaatgaatg aatccttatc cagggataag gctgcgcttt
    18061 ccggggcgat ggagagccgg aaacaaagga gaaaaaagcg aaggatgcag aaaataaatt
    18121 aaatgaggaa aagaaaaaac ctcgtaaggg aactaaagat tacggccatg attattttcc
    18181 tgatcccaag actgaagata ttaaggggtt gggagagttg aaagagggta aacctaaaac
    18241 ccctaaacaa ggtggtggtg gtaagcgggc ccgatggtat ggtgataaaa agcgtaaaat
    18301 ttatgaatgg gattcccagc acggtgagct tgaagggtac cgcgccagtg atggcgaaca
    18361 cctcggggca ttcgatccaa aaacgggtaa gcaggttaaa gggccggatc caaaacgaaa
    18421 cattaaaaat atctttaaga ggtaaatatg ggcttaaatt acatattcat tggttgataa
    18481 gaaaaccgaa gagtttaaag tggtgaatac tcaaaagact tcggtgatga tggttctgtc
    18541 attgaaagtc tggggatgcc tttaaaggat aatattaata atggttggtt tgatgttgaa
    18601 aaatcatggg tttcgatatt acagccacac tttaaaaatg taatcgatat tagtaaattt
    18661 gattactttg tatcctttgt ttaccgggat ggtaactggt aagcaaaagt tatcaaggat
    18721 gatttgaaat acagacttcc ggtgttcagg gatgaatacc ggggttttta aatacaggga
    18781 aggtatatga aaaaggtaaa ggttgttttt cttttatatt gattttttca ggctttcttc
    18841 tggtcgcatg tcaggcaaac tatatccggg atgttcaggg tggaacggtg
//
