LOCUS       NZ_CP016519             6647 bp    DNA     circular CON 05-MAR-2024
DEFINITION  Salmonella enterica subsp. enterica serovar Heidelberg strain
            CE-R2-11-0435 plasmid pCE-R2-11-0435_6, complete sequence.
ACCESSION   NZ_CP016519
VERSION     NZ_CP016519.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN05263538
            Sequence Read Archive: SRR3703080
            Assembly: GCF_001690075.1
KEYWORDS    RefSeq.
SOURCE      Salmonella enterica subsp. enterica serovar Heidelberg
  ORGANISM  Salmonella enterica subsp. enterica serovar Heidelberg
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 6647)
  AUTHORS   Labbe,G., Ziebell,K., Bekal,S., MacDonald,K., Parmley,J., Agunos,A.,
            Desruisseau,A., Daignault,D., Slavic,D., Hoang,L., Ramsay,D.,
            Pollari,F., Robertson,J., Nash,J.H.E. and Johnson,R.P.
  TITLE     Complete Genome Sequences of 17 Canadian Isolates of Salmonella
            enterica subsp. enterica Serovar Heidelberg from Human, Animal and
            Food Sources
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6647)
  AUTHORS   Labbe,G., Ziebell,K., Bekal,S., MacDonald,K., Parmley,J., Agunos,A.,
            Desruisseau,A., Daignault,D., Slavic,D., Hoang,L., Ramsay,D.,
            Pollari,F., Robertson,J., Nash,J.H.E. and Johnson,R.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JUL-2016) Public Health Agency of Canada, National
            Microbiology Laboratory at Guelph, 110 Stone Road West, Guelph,
            Ontario N1G3W4, Canada
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: MIRA v. 4.9.3
            Assembly Name                     :: SHCE-R2-11-0435
            Long Assembly Name :: Salmonella Heidelberg strain CE-R2-11-0435
            Genome Coverage                   :: 66x
            Sequencing Technology             :: Illumina HiSeq; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/04/2024 12:49:26
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,776
            CDSs (total)                      :: 4,655
            Genes (coding)                    :: 4,546
            CDSs (with protein)               :: 4,546
            Genes (RNA)                       :: 121
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 84
            ncRNAs                            :: 15
            Pseudo Genes (total)              :: 109
            CDSs (without protein)            :: 109
            Pseudo Genes (ambiguous residues) :: 0 of 109
            Pseudo Genes (frameshifted)       :: 45 of 109
            Pseudo Genes (incomplete)         :: 73 of 109
            Pseudo Genes (internal stop)      :: 26 of 109
            Pseudo Genes (multiple problems)  :: 29 of 109
            Pseudo Genes (short protein)      :: 1 of 109
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP016519.1.
            Source DNA available from Roger P. Johnson, Research Scientist and
            Chief of Reference Laboratiries, National Microbiology Laboratory
            at Guelph.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..6647
                     /organism="Salmonella enterica subsp. enterica serovar
                     Heidelberg"
                     /mol_type="genomic DNA"
                     /strain="CE-R2-11-0435"
                     /serovar="Heidelberg"
                     /isolation_source="Chicken Meat"
                     /sub_species="enterica"
                     /db_xref="taxon:611"
                     /plasmid="pCE-R2-11-0435_6"
                     /geo_loc_name="Canada: Ontario"
                     /collection_date="2011"
                     /collected_by="CNET"
                     /serogroup="B"
     gene            54..377
                     /locus_tag="BAT85_RS23145"
                     /old_locus_tag="BAT85_23620"
     CDS             54..377
                     /locus_tag="BAT85_RS23145"
                     /old_locus_tag="BAT85_23620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="WP_000955999.1"
                     /translation="MLTIRVTDDEHARLLERCEGKQLAVWMRRVCLGEPVARSGKLPTL
                     APPLLRQLAAIGNNLNQTARKVNSGQWSSGDRVQVVAALMAIGDELRRLRLAVREQGAR
                     DDS"
                     /name="MobC family plasmid mobilization relaxosome protein"
     gene            586..>1017
                     /locus_tag="BAT85_RS26445"
                     /pseudo=""
     CDS             586..>1017
                     /locus_tag="BAT85_RS26445"
                     /inference="COORDINATES: protein motif:HMM:NF015397.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /name="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            1055..1573
                     /locus_tag="BAT85_RS25995"
     CDS             1055..1573
                     /locus_tag="BAT85_RS25995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001447511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeB family mobilization protein"
                     /protein_id="WP_000067500.1"
                     /translation="MSNLLQTGAEFEKKLKERAESTEKMLNNEFRRLGESVSEAVTSNE
                     TKIRDAIALFTASTEESLEKHREGVKEAMMQHRRDVLKLAGNTGMMLLGIVFLLFTASG
                     GTLWYLGGRIQANLEEIRKQEETLQKLNAKTWGVEFVQDGNRKFLVLPYGKSAEVIPFQ
                     GKEWVHLKE"
                     /name="MbeB family mobilization protein"
     gene            1580..1813
                     /locus_tag="BAT85_RS26000"
     CDS             1580..1813
                     /locus_tag="BAT85_RS26000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeD family mobilization/exclusion protein"
                     /protein_id="WP_000137445.1"
                     /translation="MTELETHLLNALEQLQQDYMQRLSEWESAFVELQKMFSLTQRDNA
                     MLNERVMQLSQQVQHLSEQTERLSQLYSENWR"
                     /name="MbeD family mobilization/exclusion protein"
     gene            complement(2131..2550)
                     /locus_tag="BAT85_RS23155"
                     /old_locus_tag="BAT85_23630"
     CDS             complement(2131..2550)
                     /locus_tag="BAT85_RS23155"
                     /old_locus_tag="BAT85_23630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Exc2 family lipoprotein"
                     /protein_id="WP_001254967.1"
                     /translation="MRRTGNKLCLIAMITATVALTACTPKGSVEQHTRHYVYASDDGFD
                     PNFSTQKADTTRMMVPFFRQFWDMGAKDKATGKSRSDVQQRIQQFHSQEFLNSLRGTTQ
                     FAGTDYRSKDLTPKKSRLLADTISAVYLDGYEGRQ"
                     /name="Exc2 family lipoprotein"
     gene            complement(2631..3068)
                     /locus_tag="BAT85_RS23160"
                     /old_locus_tag="BAT85_23635"
     CDS             complement(2631..3068)
                     /locus_tag="BAT85_RS23160"
                     /old_locus_tag="BAT85_23635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001405929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_021532742.1"
                     /translation="MGHCHFMAWHTLRDALKMTGRSRSQFYRDMRAGLVSYRTGRDGRR
                     EFETSELIRAYGELKQNETPERHSKGHAENPHDQQTERILRELNELKQCLTLMLEDKQA
                     QDMDRRRQEAEREQLQNEIAQLRQALELEKKRGFWSRLFGR"
                     /name="hypothetical protein"
     gene            3328..4896
                     /gene="cea"
                     /locus_tag="BAT85_RS23165"
                     /old_locus_tag="BAT85_23640"
     CDS             3328..4896
                     /gene="cea"
                     /locus_tag="BAT85_RS23165"
                     /old_locus_tag="BAT85_23640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000447006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pore-forming bacteriocin colicin E1"
                     /protein_id="WP_000447006.1"
                     /translation="METAVAYYKDGVPYDDKGQVIITLLNGTPDGSGSGGGGGKGGSKS
                     ESSAAIHATAKWSTAQLKKTQAEQAARAKAAAEAQAKAKANRDALTQRLKDIVNEALRH
                     NASRTPSATELAHANNAAMQAEAERLRLAKAEEKARKEAEAAEKAFQEAEQRRKEIERE
                     KAETERQLKLAEAEEKRLAALSEEAKAVEIAQKKLSAAQSEVVKMDGEIKTLNSRLSSS
                     IHARDAEMKTLAGKRNELAQASAKYKELDELVKKLSPRANDPLQNRPFFEATRRRVGAG
                     KIREEKQKQVTASETRINRINADITQIQKAISQVSNNRNAGIARVHEAEENLKKAQNNL
                     LNSQIKDAVDATVSFYQTLTEKYGEKYSKMAQELADKSKGKKIGNVNEALAAFEKYKDV
                     LNKKFSKADRDAIFNALASVKYDDWAKHLDQFAKYLKITGHVSFGYDVVSDILKIKDTG
                     DWKPLFLTLEKKAADAGVSYVVALLFSLLAGTTLGIWGIAIVTGILCSYIDKNKLNTIN
                     EVLGI"
                     /name="cea"
     gene            complement(4893..5234)
                     /locus_tag="BAT85_RS23170"
                     /old_locus_tag="BAT85_23645"
     CDS             complement(4893..5234)
                     /locus_tag="BAT85_RS23170"
                     /old_locus_tag="BAT85_23645"
                     /inference="COORDINATES: protein motif:HMM:NF015489.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin E1 immunity protein"
                     /protein_id="WP_000058760.1"
                     /translation="MSLRYYIKNILFGLYCTLIYIYLITKNSEGYYFLVSDKMLYAIVI
                     STILCPYSKYAIEYIAFNFIKKDFFERRKNLNNAPVAKLNLFMLYNLLCLVLAIPFGLL
                     GLFISIKNN"
                     /name="colicin E1 immunity protein"
     gene            5282..5419
                     /locus_tag="BAT85_RS25100"
     CDS             5282..5419
                     /locus_tag="BAT85_RS25100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001405930.1"
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="WP_001405930.1"
                     /translation="MRKRFFVGIFAINLLVGCQANYIRDVQGGTIAPSSSSKLTGIAVQ
                     "
                     /name="colicin release lysis protein"
     gene            complement(5618..5776)
                     /locus_tag="BAT85_RS26555"
     CDS             complement(5618..5776)
                     /locus_tag="BAT85_RS26555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001354639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_071531517.1"
                     /translation="MHEPPVQPDRCALSGNYRLESNPVRHALTPLAAATGNRISRAMMA
                     QTVLQSS"
                     /name="replication initiation protein"
     gene            complement(6446..6637)
                     /locus_tag="BAT85_RS23140"
                     /old_locus_tag="BAT85_23615"
     CDS             complement(6446..6637)
                     /locus_tag="BAT85_RS23140"
                     /old_locus_tag="BAT85_23615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_000165985.1"
                     /translation="MTKQEKTALNMARFIRSQTLTLLEKLNELDADEQADICESLHDHA
                     DELYRSCLARFGDDGENL"
                     /name="Rop family plasmid primer RNA-binding protein"
     Typing          6274..6361
                     /name="MOBP"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="6.86e-39"
     Typing          complement(5705..6260)
                     /name="rep_cluster_2350"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="95.699"
                     /coverage="99.0"
                     /evalue="0.0"
     Typing          368..1917
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="98.473"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 gtgtaagggg gatttctgtt catggggtaa tgataccgat gaaacgcgag aggatgctca
       61 caatacgggt tactgatgat gaacatgccc ggttacttga acgctgtgag ggtaaacaac
      121 tggcggtatg gatgcggcgg gtctgcctgg gggagccggt tgcccgttcc ggaaaactgc
      181 cgacactggc accgccgtta ctgcgtcagc tggccgccat cggaaataac ctgaatcaga
      241 cagcccgtaa ggtgaacagc gggcagtggt cttccggtga ccgggttcag gtggtggccg
      301 cactgatggc catcggggat gagctgcgcc ggctgcgtct ggctgtcagg gaacaggggg
      361 cgcgggatga tagttaaatt tcatgccagg ggaaaaggtg gtggcagtgg tccggttgat
      421 tacctgctgg ggagggagcg taaccgcgaa ggcgcaacgg tgcttcaggg taatccggaa
      481 gaagtccggg aactcatcga tgccacgcca tttgcgaaga aatacacgtc cggtgttctg
      541 tcgttcgcgg agaaggagct gccgccggga ggacgtgaaa aagtgatggc gagctttgag
      601 cgtgtactga tgcccggtct cgaaaaaaat cagtacagca tcctgtgggt ggagcaccag
      661 gacaagggac ggcttgagct gaattttgtc attccgaaca tggagctaca gaccggaaaa
      721 cgcctccagc cgtactacga ccgcgcagac aggcctagaa ttgatgcctg gcagacgctg
      781 gtgaatcacc attacgggct gcatgacccg aacgccccgg agaaccgcag gacgctgaca
      841 ctccctgata acctgcctga aacgaaacag gcgcttgctg agggcgtcac gcgaggtata
      901 gatgcacttt accatgccgg agagataaaa ggccgtcagg atgtgattca ggcgctcact
      961 gaggcggggc tggaagtggt cagggtgacg cgaagcagta tcagcattgc agatccgaac
     1021 ggcgggaaga atatcaggct gaaaggagca ttttatgagc aatcttttgc agacgggcgc
     1081 ggagttcgag aaaaagctga aagagagagc cgaatctaca gagaaaatgc tgaacaacga
     1141 gttcaggagg ctcggcgaat ctgtaagcga ggctgtgaca tcaaacgaga cgaaaatcag
     1201 agacgctata gccctgttca cagcctcgac agaggaatcg ctggaaaaac accgggaagg
     1261 ggtgaaagag gcgatgatgc agcacaggag ggacgtgtta aagctggcag ggaatacggg
     1321 catgatgtta ctggggatag tctttctcct gtttaccgcg agtggcggga cgctctggta
     1381 tcttggaggg aggatacagg cgaacctgga agaaatcagg aagcaggaag agacattgca
     1441 gaaactgaac gcgaagacat ggggcgtgga gtttgtgcag gacgggaaca ggaaattcct
     1501 tgtccttccg tacgggaaat cagcggaggt gattcccttt caggggaaag agtgggtaca
     1561 tctgaaggag tgacacagag tgacagagct ggaaacacat ttgctgaacg ccttagagca
     1621 gctgcaacag gactatatgc agcggctgag cgaatgggag agcgccttcg tggaattgca
     1681 gaagatgttt tcgcttacgc aacgggacaa cgcgatgctg aacgagcggg tcatgcagtt
     1741 gagtcagcag gtgcagcact tgagcgagca gacagaacgc ttgagccagt tatacagcga
     1801 gaactggaga taagagagga acggctgata caggagcgcg aacatgtgtt atccctggaa
     1861 cgggagcgtc agccggaaat acaggaacgc acgctggatg gcccttcgct gggatggtga
     1921 aaccatgaaa aatggcagct tcagtggatt aagtgggggt aatgtggcct gtaccctctg
     1981 gttgcatagg tattcatacg gttaaaattt atcaggcgcg atcgcggcag tttttcgggt
     2041 ggtttgttgc catttttacc tgtctgctgc cgtgatcgcg ctgaacgcgt tttagcggtg
     2101 cgtacaatta agggattatg gtaaatccac ttactgtctg ccctcgtagc catcgagata
     2161 aaccgcagaa atcgtgtcag ccagcagcct ggattttttc ggggtaaggt ctttgctgcg
     2221 gtaatcagta cccgcaaatt gagttgtgcc ccggagtgag tttaaaaatt cctggctgtg
     2281 aaactgctga atgcgttgtt gcacatcact ccgtgatttt cctgtcgctt tatctttagc
     2341 tcccatatcc cagaactgcc gaaaaaaagg caccatcatt cgtgttgtgt cggctttttg
     2401 ggtggaaaag ttgggatcaa aaccgtcatc agaagcatat acgtaatgcc gggtatgttg
     2461 ttccacgctg ccctttgggg tacaggctgt gagagctact gttgctgtta tcatggcgat
     2521 aagacaaagt ttgtttccgg tacgtctcat gagtgtctcc ctaccttaaa gtatttattc
     2581 tcggtgagtt attatccgaa gactatttta tcatcagtct ctgacagcgt tcagcgaccg
     2641 aacaacctgg accagaatcc ccgtttcttt tccagttcca gtgcctgcct gagctgggct
     2701 atctcatttt gtagctgttc ccgttctgct tcctggcgtc tgcgatccat atcctgtgcc
     2761 tgtttatcct caagcatcag cgtcaggcat tgtttcagct cattcagctc ccggagaatg
     2821 cgttctgtct gctgatcatg tggattttct gcatgtccct tactgtgcct ttctggtgtc
     2881 tcattctgct ttaattcgcc gtatgcccgg atcagttcac tggtttcaaa ctcccgtcgt
     2941 ccgtccctgc cggtacggta actgacaagg cctgcgcgca tatcacggta aaactgtgaa
     3001 cgcgatctgc ctgtcatttt tagtgcgtcc cggagtgtgt gccatgccat aaagtgacag
     3061 tgtcccatag atgtctcatc tcatagtttc agtaaaacat aatgaggtct gagaacggta
     3121 atgtttgtgc tggtttttgt ggcatcgggc gagaatagcg cgtggtgtga aagactgttt
     3181 ttttgatcgt tttcacaaaa atggaagtcc acagtcttga cagggaaaat gcagcggcgt
     3241 agcttttatg ctgtatataa aaccagtggt tatatgtaca gtatttattt ttaacttatt
     3301 gttttaaaag tcaaagagga ttttataatg gaaaccgcgg tagcgtacta taaagatggt
     3361 gttccttatg atgataaggg acaggtaatt attactcttt tgaatggtac tcctgacggg
     3421 agtggctctg gcggcggagg tggaaaagga ggcagtaaaa gtgaaagttc tgcagctatt
     3481 catgcaactg ctaaatggtc tactgctcaa ttaaagaaaa cacaggcaga gcaggctgcc
     3541 cgggcaaaag ctgcagcgga agcacaggcg aaagcaaagg caaacaggga tgcgctgact
     3601 cagcgcctga aggatatcgt gaatgaggct cttcgtcaca atgcctcacg tacgccttca
     3661 gcaacagagc ttgctcatgc taataatgca gctatgcagg cggaagcaga gcgtttgcgc
     3721 cttgcgaaag cagaagaaaa agcccgtaaa gaagcggaag cagcagaaaa ggcttttcag
     3781 gaagcagaac aacgacgtaa agagattgaa cgggagaagg ctgaaacaga acgccagttg
     3841 aaactggctg aagctgaaga gaaacgactg gctgcattga gtgaagaagc taaagctgtt
     3901 gagatcgccc aaaaaaaact ttctgctgca caatctgaag tggtgaaaat ggatggagag
     3961 attaagactc tcaattctcg tttaagctcc agtatccatg cccgtgatgc agaaatgaaa
     4021 acgctcgctg gaaaacgaaa tgaactggct caggcatccg ctaaatataa agaactggat
     4081 gagctggtca aaaaactatc accaagagcc aatgatccgc ttcagaaccg tccttttttt
     4141 gaagcaacca gacgacgggt tggggccggt aagattagag aagaaaaaca aaaacaggta
     4201 acagcatcag aaacacgtat taaccggata aatgctgata taactcagat ccagaaggct
     4261 atttctcagg tcagtaataa tcgtaatgcc ggtatcgctc gtgttcatga agctgaagaa
     4321 aatttgaaaa aagcacagaa taatctcctt aattcacaga ttaaggatgc tgttgatgca
     4381 acagttagct tttatcaaac gctgactgaa aaatatggtg aaaaatattc gaaaatggca
     4441 caggaacttg ctgataagtc taaaggtaag aaaatcggca atgtgaatga agctctcgct
     4501 gcttttgaaa aatacaagga tgttttaaat aagaaattca gcaaagccga tcgtgatgct
     4561 atttttaatg cgttggcatc ggtgaagtat gatgactggg ctaaacattt agatcagttt
     4621 gccaagtact tgaagattac ggggcatgtt tcttttggat atgatgtggt atctgatatc
     4681 ctaaaaatta aggatacagg tgactggaag ccactatttc ttacattaga gaagaaagct
     4741 gcagatgcag gggtgagtta tgttgttgct ttacttttta gcttgcttgc tggaactaca
     4801 ttaggtattt ggggtattgc tattgttaca ggaattctat gctcctatat tgataagaat
     4861 aaacttaata ctataaatga ggtgttaggg atttaattat tctttattga tataaaaagt
     4921 cctagcaatc caaatgggat tgctaggacc aaacaaagta gattatatag cataaatagg
     4981 tttaattttg ctacgggggc gttatttagg ttttttcttc tttcgaaaaa atctttcttt
     5041 atgaagttaa aagctatgta ttcaatagca tattttgaat atggacatag aatagtgctt
     5101 atcactattg catatagcat cttatctgac acaaggaaat aatacccttc gctgtttttt
     5161 gttataaggt atatatatat aagtgtgcag tacaggccaa ataaaatatt ttttatgtag
     5221 tatcttaagc tcataaatta aacctcgcca tatattcttt tcattttata aggatcgagt
     5281 tatgaggaaa agattttttg tgggaatatt cgcgataaac ctccttgttg gatgtcaggc
     5341 taactatata cgtgatgttc agggagggac catcgcacca tcctcctctt ctaaactgac
     5401 ggggatcgcg gttcagtaga aaagatcaaa ggatcttctt gagatccttt ttttctgcgc
     5461 gtaatctgct gcttgcaaac aaaaaaacca ccgctaccaa cggtggtttg tttgccggat
     5521 caagagctac caactctttt tccgaaggta actggcttca gcagagcgca gataccaaat
     5581 actgtccttc tagtgtagcc gtagtcgggc cactacttca agaactctgt agcaccgttt
     5641 gtgccatcat cgctctgcta atccggttac cagtggctgc tgccagtggc gttaaggcgt
     5701 gccttaccgg gttggactca agacgatagt taccggataa ggcgcagcgg tcgggctgaa
     5761 cggggggttc gtgcacacag cccagcttgg agcgaacgac ctacaccgaa ctgagatacc
     5821 aacagcgtga gctatgagaa agcgccacgc ttcccgaagg gagaaaggcg gacaggtatc
     5881 cggtaagcgg cagggtcgga acaggagagc gcacgaggga gcttccaggg ggaaacgcct
     5941 ggtatcttta tagtcctgtc gggtttcgcc acctctgact tgagcgtcta tttttgtgat
     6001 gctcgtcagg ggggcggagc ctatggaaaa acgcctgcta cgtggccttc ttcctgttcc
     6061 tggtcttttg ctcacatgtt ctttccggcc ttatcccctg attctgtgga taactgtgtt
     6121 accgtttttg tgtgagtcag taccgctcgc cgcagtcgaa cgaccgagcg tagcgagtca
     6181 gtgagcgagg aagcggaaaa gcgcctggac gtgcattttc tccttacgca tctgtgcggc
     6241 atttcacacc cggcatggcg tacttttcat acaatccgca ctgatgccgc atggttaagc
     6301 cagtatacac tccgctatcg ctacgtgact gggtcagggc tgcgccccga cacccgctaa
     6361 aacctgctga cgcgccctga cgggcttgtc agctcccggc atccgctcac agacaagctg
     6421 tgaccgtctc cgggagctgc atgtgtcaga ggttttcacc gtcatccccg aaacgtgcga
     6481 ggcagctgcg gtaaagctca tcggcgtggt cgtgaagcga ttcacaaata tcggcctgtt
     6541 catctgcgtc cagttcgttg agcttctcca gcagcgttaa tgtctggctt ctgataaagc
     6601 gggccatgtt aagggcggtt ttttcctgtt tagtcactga tgcctcc
//
