LOCUS       NZ_CP014408            27098 bp    DNA     circular CON 08-MAY-2024
DEFINITION  Staphylococcus aureus strain USA300-SUR12 plasmid pUSA04-1-SUR12,
            complete sequence.
ACCESSION   NZ_CP014408
VERSION     NZ_CP014408.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN04497606
            Assembly: GCF_002000625.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 27098)
  AUTHORS   Sabat,A.J., Hermelijn,S.M., Akkerboom,V., Juliana,A., Degener,J.E.,
            Grundmann,H. and Friedrich,A.W.
  TITLE     Complete-genome sequencing elucidates outbreak dynamics of CA-MRSA
            USA300 (ST8-spa t008) in an academic hospital of Paramaribo,
            Republic of Suriname
  JOURNAL   Sci Rep 7, 41050 (2017)
   PUBMED   28106148
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27098)
  AUTHORS   Sabat,A.J., Hermelijn,S., Akkerboom,V., Degener,J.E., Grundmann,H.
            and Friedrich,A.W.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-FEB-2016) Medical Microbiology, University Medical
            Center Groningen, Hanzeplein 1, Groningen 9700 RB, The Netherlands
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SeqMan NGen v. 12.1.0
            Genome Coverage                   :: missing
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002000625.1-RS_2024_05_07
            Annotation Date                   :: 05/07/2024 02:23:38
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,926
            CDSs (total)                      :: 2,845
            Genes (coding)                    :: 2,754
            CDSs (with protein)               :: 2,754
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 48 of 91
            Pseudo Genes (incomplete)         :: 42 of 91
            Pseudo Genes (internal stop)      :: 20 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP014408.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..27098
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="USA300-SUR12"
                     /isolation_source="Wound left foot"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="pUSA04-1-SUR12"
                     /geo_loc_name="Suriname: Paramaribo"
                     /lat_lon="5.866667 N 55.166667 W"
                     /collection_date="2013-05-09"
                     /collected_by="Sandra Hermelijn"
     gene            join(26889..27098,1..465)
                     /locus_tag="AYM25_RS15140"
                     /old_locus_tag="AYM25_14760"
     CDS             join(26889..27098,1..465)
                     /locus_tag="AYM25_RS15140"
                     /old_locus_tag="AYM25_14760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105956.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            <606..1241
                     /locus_tag="AYM25_RS15145"
                     /pseudo=""
     CDS             <606..1241
                     /locus_tag="AYM25_RS15145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009251744.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /name="aminoglycoside 6-adenylyltransferase"
     gene            1238..1768
                     /gene="sat4"
                     /locus_tag="AYM25_RS15150"
                     /pseudo=""
     CDS             1238..1768
                     /gene="sat4"
                     /locus_tag="AYM25_RS15150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /name="sat4"
     gene            1861..2655
                     /gene="aph(3')-IIIa"
                     /locus_tag="AYM25_RS15155"
                     /old_locus_tag="AYM25_14780"
     ARG             1862..2652
                     /name="aph(3')-IIIa"
                     /gene="aph(3')-IIIa"
                     /gene_name="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            3137..>3612
                     /locus_tag="AYM25_RS15775"
                     /old_locus_tag="AYM25_14785"
                     /pseudo=""
     CDS             3137..>3612
                     /locus_tag="AYM25_RS15775"
                     /old_locus_tag="AYM25_14785"
                     /inference="COORDINATES: protein motif:HMM:NF024676.4"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /name="WYL domain-containing protein"
     gene            complement(3671..4345)
                     /locus_tag="AYM25_RS15170"
                     /old_locus_tag="AYM25_14790"
     CDS             complement(3671..4345)
                     /locus_tag="AYM25_RS15170"
                     /old_locus_tag="AYM25_14790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105991.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            4607..4792
                     /locus_tag="AYM25_RS15520"
                     /old_locus_tag="AYM25_14795"
     CDS             4607..4792
                     /locus_tag="AYM25_RS15520"
                     /old_locus_tag="AYM25_14795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001037130.1"
                     /translation="MNKLEKWSLVFIIFTFLSSLALLYFKYNFSSVMPVLSLSILTILI
                     LLTSIITVVSVNDEDT"
                     /name="hypothetical protein"
     gene            complement(5015..5593)
                     /locus_tag="AYM25_RS15175"
                     /old_locus_tag="AYM25_14800"
     CDS             complement(5015..5593)
                     /locus_tag="AYM25_RS15175"
                     /old_locus_tag="AYM25_14800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690624.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690637.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLNLLKTLYDNGTPI
                     KTIAEQWQVSRTTIYRYLNKLEAKENKNK"
                     /name="recombinase family protein"
     gene            complement(5857..6237)
                     /gene="blaI"
                     /locus_tag="AYM25_RS15180"
                     /old_locus_tag="AYM25_14805"
     ARG             complement(5861..6237)
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="98.41"
                     /coverage="100.0"
     gene            complement(6227..7984)
                     /gene="blaR1"
                     /locus_tag="AYM25_RS15185"
                     /old_locus_tag="AYM25_14810"
     ARG             complement(6231..7984)
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.38"
                     /coverage="100.0"
     gene            8091..8936
                     /gene="blaZ"
                     /locus_tag="AYM25_RS15190"
                     /old_locus_tag="AYM25_14815"
     ARG             8092..8933
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(9462..9881)
                     /locus_tag="AYM25_RS15195"
                     /old_locus_tag="AYM25_14820"
     CDS             complement(9462..9881)
                     /locus_tag="AYM25_RS15195"
                     /old_locus_tag="AYM25_14820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418034.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_000418035.1"
                     /translation="MELDNCINYLLSTSQNRVFKHFKSLLSPYNITPAEYGVLNCLINS
                     NLNTPKAIGNTLNLEPSTISGILDKMSKKDLITRQTDNENRRTVLINSTNKAKDLWPTL
                     EKKAYQLNNHYFANLTNEETVVFKKILLKINKTTF"
                     /name="MarR family transcriptional regulator"
     gene            10005..10976
                     /locus_tag="AYM25_RS15200"
                     /old_locus_tag="AYM25_14825"
     CDS             10005..10976
                     /locus_tag="AYM25_RS15200"
                     /old_locus_tag="AYM25_14825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="WP_000481279.1"
                     /translation="MFNAVVVRKSASNVSYKVEKVDESHLSKGDVLVKVVYSSINYKDM
                     LALQYKGGVIRDYPMIPGIDFAGIVESSSNDKFKEGDNVLVTGYDVGVTHTGGFSEYAQ
                     VPGEWIVPIPQEMSIKESMVYGTAGFTAALSIFELEKYGMNIKSQPEILVSGATGGVGS
                     VAIQILHKIGYENITAIVRKEKQIEIAKKLGAKQVIIIEDDNKPLKKGIFDYFLDTVGS
                     NVTLYGLKRLNYQGVATVCGNVAGNSLNANILPFILRGIKLIGIDSVYVDHNIREDIWS
                     KLANEWNIGNSLLYNEIGFEEFYKTIDQLLKGQHLGRTILKV"
                     /name="oxidoreductase"
     gene            complement(11148..11240)
                     /locus_tag="AYM25_RS15500"
     CDS             complement(11148..11240)
                     /locus_tag="AYM25_RS15500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(11397..11744)
                     /locus_tag="AYM25_RS15205"
                     /old_locus_tag="AYM25_14830"
     CDS             complement(11397..11744)
                     /locus_tag="AYM25_RS15205"
                     /old_locus_tag="AYM25_14830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119690.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNHEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            complement(11763..12380)
                     /gene="cadD"
                     /locus_tag="AYM25_RS15210"
                     /old_locus_tag="AYM25_14835"
     ARG             complement(11767..12380)
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(13496..13690)
                     /locus_tag="AYM25_RS15220"
                     /old_locus_tag="AYM25_14840"
     CDS             complement(13496..13690)
                     /locus_tag="AYM25_RS15220"
                     /old_locus_tag="AYM25_14840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001004925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001004925.1"
                     /translation="MNENLEKYIKSLPLLGLLISILLIVLFFFILDVDEDLFVVFLYCL
                     LPLIVNLSIYGFYVFVKRK"
                     /name="hypothetical protein"
     gene            13800..14492
                     /locus_tag="AYM25_RS15225"
                     /old_locus_tag="AYM25_14845"
     CDS             13800..14492
                     /locus_tag="AYM25_RS15225"
                     /old_locus_tag="AYM25_14845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative immunity/bacteriocin fusion bifunctional
                     protein"
                     /protein_id="WP_000691527.1"
                     /translation="MKIIKLFSIISLFLLVFSANFSNAYANEEQKSSLLENQKEKLKSK
                     NIEVSQMTKKEISFLEQLQNKNEDMQKFEKQMKKEGFKKIKLEDKNSKLKYLATEANDK
                     NAYGYIANNAYKNEKTKEIVVSETIYDNYNKKITKFIAEKRSMTENKEGKILINKNYVE
                     YKAEKVDKNRPVTYAGFKWNGKAFACSMAGLYACAHYCGVWAIVNPIAGGVCEAVCGTA
                     FAAGCSVG"
                     /name="putative immunity/bacteriocin fusion bifunctional
                     protein"
     gene            complement(14660..14809)
                     /locus_tag="AYM25_RS15620"
     CDS             complement(14660..14809)
                     /locus_tag="AYM25_RS15620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000695366.1"
                     /translation="MKIKTFATFTHRQLDKQVNRFLKNDIHVLEIQTHSNWLYISAIVF
                     YEDK"
                     /name="hypothetical protein"
     gene            complement(15385..>15675)
                     /locus_tag="AYM25_RS15235"
                     /pseudo=""
     CDS             complement(15385..>15675)
                     /locus_tag="AYM25_RS15235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009384749.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            complement(15695..16678)
                     /locus_tag="AYM25_RS15240"
                     /old_locus_tag="AYM25_14855"
     CDS             complement(15695..16678)
                     /locus_tag="AYM25_RS15240"
                     /old_locus_tag="AYM25_14855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_001181107.1"
                     /translation="MQNQYFTVQENYKERFYQIPKVFFTSENYKNLTNDMKIAYAILRD
                     RLNLSIKNSWVDEDGNIYFVYSNEKLMEILNCKKEKLTKIKKGLENDGLLIQKRRGLNK
                     PNILYLMKPIVTERDIYKIEKEENDVEPYGEKEVRKSNVQKFENRTSRSSKIERPEVRK
                     SNTNDTDFNDIDFNDTENNDMNDLNDIKYKNEISNHSNHSNQFTHNFDDKEMLLQEFPE
                     QLTNYLLKYDYRDLEIIKAVILKAKKSFNSRHEDMHYMLEDIEDEILTSLKRLKKAIHD
                     RGVKGQKETIKSMQAYLMQTILTELEETHALYMRRKNMKQYNIFNQ"
                     /name="replication initiator protein A"
     gene            17104..17847
                     /locus_tag="AYM25_RS15245"
                     /old_locus_tag="AYM25_14860"
     CDS             17104..17847
                     /locus_tag="AYM25_RS15245"
                     /old_locus_tag="AYM25_14860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843732.1"
                     /translation="MKSVKKLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESTTEDKQKKGSDNINFESKSDAQIVEILKNQIDTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNTR
                     QNVDAQEKTYTTNPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAKKEDVPANLND
                     NDSDIEEKSEETEPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     gene            complement(18074..18259)
                     /locus_tag="AYM25_RS15250"
                     /old_locus_tag="AYM25_14865"
     CDS             complement(18074..18259)
                     /locus_tag="AYM25_RS15250"
                     /old_locus_tag="AYM25_14865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011276570.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000797248.1"
                     /translation="MKNRIREYRKQKGISQETLSKELKVSRQTINAIENNKYDPTLTLA
                     FKLARLFDTTVDELFS"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(18264..18602)
                     /locus_tag="AYM25_RS15255"
                     /old_locus_tag="AYM25_14870"
     CDS             complement(18264..18602)
                     /locus_tag="AYM25_RS15255"
                     /old_locus_tag="AYM25_14870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001049146.1"
                     /translation="MNLIPFIIILIFSCLWTAITNKYLPSETLDKKGQQDRYDERQRKM
                     FIEILAKSFIWIVYCMLFTLVLKFTGLSPSIEGSWFSQYPEIFFIIVALFLMLFNYYTT
                     NKKYTSKG"
                     /name="hypothetical protein"
     gene            complement(18848..19456)
                     /locus_tag="AYM25_RS15260"
                     /old_locus_tag="AYM25_14875"
     CDS             complement(18848..19456)
                     /locus_tag="AYM25_RS15260"
                     /old_locus_tag="AYM25_14875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002474535.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000583528.1"
                     /translation="MIIGYARVSSIDQNLERQLDNLKTFGVEKIFTEKQSGKSVENRPV
                     FQEALNFVRMGDRFVVESIDRLGRNYDEIIETVNYLKEKDVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRV
                     IYHRVVEMLEEGKAISKIAKEVNITRQTVYRIKHDKGLS"
                     /name="recombinase family protein"
     gene            complement(19942..20841)
                     /locus_tag="AYM25_RS15265"
                     /old_locus_tag="AYM25_14880"
     CDS             complement(19942..20841)
                     /locus_tag="AYM25_RS15265"
                     /old_locus_tag="AYM25_14880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mph(C) family macrolide 2'-phosphotransferase"
                     /protein_id="WP_000196697.1"
                     /translation="MTRHNEIIKCAEKYQLHIQPQTISLNESGLDFQVAFGKDKHGVEW
                     VLRLPRRPDVYKRTKPEKQTVDFLQKNVSFEIPKWKVHAKDLIAYPKLTGKPAATIDPE
                     IQNYVWEIEHKPLPENFINTLAETLVDLHNIPEENINVQHINIKTIQEIKNDFQRRMNK
                     VKETYGVSDELWNRWKQWLENDELWPRHATMIHGDLHPGHIMVDNQANVTGLIDWTEAT
                     HSDPSMDFIGHHRVFDDEGLEQLITAYGKAGGEIWPRMKEHIIELNAVFPMFIAEFAME
                     SGESAYETMALKELGMKE"
                     /name="Mph(C) family macrolide 2'-phosphotransferase"
     gene            complement(20940..22406)
                     /gene="msr(A)"
                     /locus_tag="AYM25_RS15270"
                     /old_locus_tag="AYM25_14885"
     ARG             complement(20944..22406)
                     /name="msr(A)"
                     /gene="msr(A)"
                     /gene_name="ABC-F type ribosomal protection protein Msr(A)"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE/STREPTOGRAMIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            22880..23554
                     /locus_tag="AYM25_RS15275"
                     /old_locus_tag="AYM25_14890"
     CDS             22880..23554
                     /locus_tag="AYM25_RS15275"
                     /old_locus_tag="AYM25_14890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="WP_001105960.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            <23612..23989
                     /locus_tag="AYM25_RS15280"
                     /old_locus_tag="AYM25_14895"
                     /pseudo=""
     CDS             <23612..23989
                     /locus_tag="AYM25_RS15280"
                     /old_locus_tag="AYM25_14895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019834602.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]; GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /name="response regulator transcription factor"
     gene            23986..24867
                     /locus_tag="AYM25_RS15285"
                     /old_locus_tag="AYM25_14905"
                     /pseudo=""
     CDS             23986..24867
                     /locus_tag="AYM25_RS15285"
                     /old_locus_tag="AYM25_14905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015581923.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0000155 - phosphorelay sensor kinase activity [Evidence
                     IEA]; GO:0004673 - protein histidine kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /name="sensor histidine kinase"
     gene            24983..25912
                     /locus_tag="AYM25_RS15290"
                     /old_locus_tag="AYM25_14910"
     CDS             24983..25912
                     /locus_tag="AYM25_RS15290"
                     /old_locus_tag="AYM25_14910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000074567.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016887 - ATP hydrolysis activity [Evidence IEA];
                     GO:0042626 - ATPase-coupled transmembrane transporter
                     activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000793446.1"
                     /translation="MKNLNNIIEINNLTKQYGSQIAVNNLSITVESGQIYGFLGRNGAG
                     KTTTIRMLLGLIKPTKGNIKIFEKEFESNKTEILKNIGAMVETPGFYSNLTAKENLTIN
                     AKILGIQKENAIEEVLEIVGLASEKVKLFKNYSLGMKQRLGIARALLHNPELLILDEPT
                     NGLDPIGIKEIRKLIKDLAQSRNITILISSHILSEIEQLVDKVGIIHNGVLLEEIMYED
                     LKKKNRQFISISVSDEEKVACLLETNFGIYDYKIKENGEFKIYSHIDRQQEINRLLVLN
                     NIDVFQMRVIEDNLETYFEDLVGGGTIG"
                     /name="ABC transporter ATP-binding protein"
     gene            25905..26642
                     /locus_tag="AYM25_RS15295"
                     /old_locus_tag="AYM25_14915"
     CDS             25905..26642
                     /locus_tag="AYM25_RS15295"
                     /old_locus_tag="AYM25_14915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000369394.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="WP_000369394.1"
                     /translation="MDNLLRTEFIKLKRSYMFLISILGTCVAPFMVVVASFISMRTKVP
                     TPNIVFKQLFEEVSLYHMLIIGPPLYGVIIAYLFGREYIEDTLKNLLIIPISRESFLVS
                     KIILLFLWIQTLSVIAWLLTLMLGMLLHFQGLSQSLIIDSFFTFVIGGVLLWILSPPII
                     ILSIYFKNYVPTIVLTIIITLINLMTANSEHRGLFPWAAVGDISRGTLPNTYPFLLSLI
                     IIIVTSIFSVIILFSYFKKTDIS"
                     /name="ABC transporter permease"
     gene            26656..>26832
                     /locus_tag="AYM25_RS15300"
                     /old_locus_tag="AYM25_14920"
                     /pseudo=""
     CDS             26656..>26832
                     /locus_tag="AYM25_RS15300"
                     /old_locus_tag="AYM25_14920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499250.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016311 - dephosphorylation [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /name="undecaprenyl-diphosphate phosphatase"
     ARG             complement(19946..20841)
                     /name="mph(C)"
                     /gene="mph(C)"
                     /gene_name="Mph(C) family macrolide 2'-phosphotransferase"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(20941..22406)
                     /name="msrA"
                     /gene="msrA"
                     /gene_name="msr-type ABC-F protein"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; streptogramin
                     antibiotic; streptogramin B antibiotic"
                     /identity="98.36"
                     /coverage="100.0"
     ARG             complement(19943..20841)
                     /name="mphC"
                     /gene="mphC"
                     /gene_name="macrolide phosphotransferase (MPH)"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="98.66"
                     /coverage="100.0"
     ARG             1251..1468
                     /name="SAT-4"
                     /gene="SAT-4"
                     /gene_name="streptothricin acetyltransferase (SAT)"
                     /tool="rgi"
                     /drug_class="nucleoside antibiotic"
                     /identity="98.61"
                     /coverage="40.0"
     ARG             643..944
                     /name="aad(6)"
                     /gene="aad(6)"
                     /gene_name="ANT(6)"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="99.0"
                     /coverage="36.23"
     ARG             8092..8936
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     Typing          complement(15151..15315)
                     /name="MOB_unknown"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="2.42e-81"
     Typing          complement(15388..15564)
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="92.697"
                     /coverage="94.0"
                     /evalue="2.89e-66"
     Typing          complement(15696..16678)
                     /name="rep_cluster_2100"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.593"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          17105..17847
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 tacaaatggc gtattgatga gacgtatatc aaaataaaag gaaaatggag ctatttatat
       61 cgtgccattg atacagaggg acatacatta gatatttggt tgcgtaagca acgagataat
      121 cattcagcat atgcgtttat caaacgtctc attaaacaat ttggtaaacc tcaaaaggta
      181 attacagatc aggcaccttc aacgaaggta gcaatggtta aagtaattaa agcttttaaa
      241 cttaaacctg actgccattg tacatcgaaa tatctgaata acctcattga gcaagatcac
      301 cgtcatatta aagtaagaaa gacaaggtat caaagtatca atacagcaaa gaatacttta
      361 aaaggtattg agtgtattta cgctctatat aaaaagaacc gcaggtctct tcagatctac
      421 ggattttcgc catgccacga aattagcatc atgctagcaa gttaaacgaa cactgacatg
      481 atatattagt gattagctat attttttact ttgcaacaga accatcattt ttattaaaat
      541 actcttttgt aaaatctttc tgctcttcaa tgtatttaat ttctttacct ctaaatctat
      601 tatagctatt tgatgattac aataaaattg atcttacctt attgcccttg gaagagttag
      661 ataattacct aaagggcgat aaattaataa aggttctaat tgataaagat tgtagaatta
      721 aaagggacat agttccgact gatatagatt atcatgtaag aaagccaagc gcaagggagt
      781 atgatgattg ctgcaatgaa ttttggaatg taacacctta tgttattaaa ggattgtgcc
      841 gtaaggaaat tttatttgct attgatcatt ttaatcagat tgttcgccat gagctgctga
      901 gaatgatatc atggaaggtc ggcatcgaaa caggctttaa atgaagtgta ggcaagaact
      961 ataagtttat tgaaaggtat atatccgagg atttgtggga gaaacttttg tccacctacc
     1021 ggatggattc ctatgaaaac atatgggaag cattatttct atgccatcaa ttgttcaggg
     1081 cggtatccgg tgaggtggcg gaaaggcttc attatgccta tccggagtat gataggaata
     1141 taacaaaata taccagggac atgtataaaa aatacactgg taaaaccggc tgcctggata
     1201 gcacatatgc cgctgatata gaagagaggc gggaacagtg attacagaaa tgaaagcagg
     1261 gcacctgaaa gatatcgata aacccagcga accatttgag gtgataggta agattatacc
     1321 gaggtatgaa aacgagaatt ggacctttac agaattactc tatgaagcgc catatttaaa
     1381 aagctaccaa gacgaagagg atgaagagga tgaggaggca gattgccttg aatatattga
     1441 caatactgat aagataatat atctttaata ccaagacgat aaatgcgtcg gaaaagttaa
     1501 actgcgaaaa aattggaacc ggtacgctta tatagaagat atcgccgtat gtaaggattt
     1561 cagggggcaa ggcataggca gcgcgcttat caatatatct atagaatggg caaagcataa
     1621 aaacttgcat ggactaatgc ttgaaaccca ggacaataac cttatagctt gtaaattcta
     1681 tcataattgt ggtttcaaaa tcggctccgt cgatactatg ttatacgcca actttgaaaa
     1741 agctgttttc tggtatttaa ggttttagaa tgcaaggaac agtgaattgg agttcgtctt
     1801 gttataatta gcttcttggg gtatctttaa atactgtaga aaagaggaag gaaataataa
     1861 atggctaaaa tgagaatatc accggaattg aaaaaactga tcgaaaaata ccgctgcgta
     1921 aaagatacgg aaggaatgtc tcctgctaag gtatataagc tggtgggaga aaatgaaaac
     1981 ctatatttaa aaatgacgga cagccggtat aaagggacca cctatgatgt ggaacgggaa
     2041 aaggacatga tgctatggct ggaaggaaag ctgcctgttc caaaggtcct gcactttgaa
     2101 cggcatgatg gctggagcaa tctgctcatg agtgaggccg atggcgtcct ttgctcggaa
     2161 gagtatgaag atgaacaaag ccctgaaaag attatcgagc tgtatgcgga gtgcatcagg
     2221 ctctttcact ccatcgacat atcggattgt ccctatacga atagcttaga cagccgctta
     2281 gccgaattgg attacttact gaataacgat ctggccgatg tggattgcga aaactgggaa
     2341 gaagacactc catttaaaga tccgcgcgag ctgtatgatt ttttaaagac ggaaaagccc
     2401 gaagaggaac ttgtcttttc ccacggcgac ctgggagaca gcaacatctt tgtgaaagat
     2461 ggcaaagtaa gtggctttat tgatcttggg agaagcggca gggcggacaa gtggtatgac
     2521 attgccttct gcgtccggtc gatcagggag gatatcgggg aagaacagta tgtcgagcta
     2581 ttttttgact tactggggat caagcctgat tgggagaaaa taaaatatta tattttactg
     2641 gatgaattgt tttagtacct agatttagat gtctaaaaag ctttaactac aagcttttta
     2701 gacatctaat cttttctgaa gtacatccgc aactgtccat actctgatgt tttatatctt
     2761 ttctaaaagt tcgctagata gagttctata ttagagatgt aaagagtttt ggtgaagagg
     2821 tttgtgagta tggcttttat aaccagggtg caatgagaag cactaacagc agctagctta
     2881 agaacgcata ggatatactt tttatggaag tcacagagga ggaataaaat ttgaacagga
     2941 ttaacagagt aacctctatt cttattcagc tgcaatcaaa aaaataattc ctgccaaaga
     3001 aattgcacag cgatttaata taagcttaag gacagtttac agagatatcc ggacacttga
     3061 agaagccgga ataccaattg gatctgaggc cggaaaagga tattttcttg tagagggctt
     3121 cctacttctg ccggtaatgt ttacagcggc ggaagtgggt gcattgatta cagcagggaa
     3181 atttttaaat tgccatggag atgaatcatt tataaaggat tttgattcag ctatgtataa
     3241 aatcaaatct attttgaagc atggtgaaaa aaactatgca caggagttgg agaacagtat
     3301 taacgtgtac agcacatctg gacagaaaaa tacattggcg gataacgtta ttgcagcaat
     3361 tcagactgca atctgcaata aaagggtaat atcaattcaa tatcctgcat caggagggca
     3421 agaaccggaa agcagaatga tagagcctat atcactgggg ttttatgaac agaactggta
     3481 cttaatcggt tttgcaggct aagaaatgaa tataggaatt ttcgtgtgga tcggattaaa
     3541 agcatttgca tagaagaaga gctctgtcaa agccatgatg gctctttgga acaaatatta
     3601 aaacaaatgc tggttctgtt gcaaagtaaa aaaatatagc taaccactaa tttatcatgt
     3661 cagtgttcgc ttaacttgct agcatgatgc taatttcgtg gcatggcgaa aatccgtaga
     3721 tctgaagaga cctgcggttc tttttatata gagcgtaaat acactcaata ccttttaaag
     3781 tattctttgc tgtattgata ctttgatacc ttgtctttct tactttaata tgacggtgat
     3841 cttgctcaat gaggttattc agatatttcg atgtacaatg gcagtcaggt ttaagtttaa
     3901 aagctttaat tactttaacc attgctacct tcgttgaagg tgcctgatct gtaattacct
     3961 tttgaggttt accaaattgt ttaatgagac gtttgataaa cgcatatgct gaatgattat
     4021 ctcgttgctt acgcaaccaa atatctaatg tatgtccctc tgcatcaatg gcacgatata
     4081 aatagctcca ttttcctttt attttgatgt acgtctcatc aatacgccat ttgtaataag
     4141 cttttttatg ctttttcttc caaatttgat ataaaattgg ggcatattct tgaacccaac
     4201 ggtagaccgt tgaatgatga acgtttacac cacgttccct taatatttca gatatatcac
     4261 gataactcaa tgcatatctt agatagtagc caacagctac agtgataaca tccttgttaa
     4321 attgtttata tctgaaatag ttcatacaga agactccttt ttgttaaaat tatactataa
     4381 attcaacttt gcaacagaac ctcatttact atatgggcat ctctttcatt attaatacaa
     4441 agctttgtat ctccgatatt aggcaaaggt gtaaacgaat taggtgatac tataggattc
     4501 aacattatat taatcgtttc tttaataatg attatcttct tattttttat aaatcgtagt
     4561 aaaaatatct cctatgatta tataaaagtt caaagaggtg aagccaatga ataaattaga
     4621 aaaatggtct ttggtattta ttatttttac atttctctct tcattagcac ttttatattt
     4681 caaatataat tttagttcgg ttatgccagt cctaagtctt tctattttaa ctatactaat
     4741 attgttgacg agtattatta ctgtagtttc agttaatgat gaagatactt aaaacgttca
     4801 ttagtgaaac aggtattata ttaaaaaagc gtacgaattt gtacgctttt ttcttgtgtt
     4861 attattaaaa tctcataaca ggaaaatatt atgagatttt agacgctgtc agaacgtctc
     4921 ttttacatcg agtgacattg aatcaaagtc tttgtatgtt aatgatatat aaaattattt
     4981 agtagattca ttatagtaag ctagattagt tgctctactt gtttttattc tcttttgcct
     5041 ctaatttatt gagataacga taaatagttg tacgtgaaac ttgccactgc tctgcaattg
     5101 ttttaattgg cgtaccatta tcataaagtg tcttaagtaa gtttaaatct tgtttattta
     5161 atttttcagg tctacctcca tatcggcctc tagcacgtgc tgcaattcga ccggctgatg
     5221 atcgctctaa aattaaatta cgttcaaact ctgcaaatgc tgcgaataaa tgaaataata
     5281 attgtcctgt agaacttgat ttatccatcg ttatattttc ttctaaacta tgaaaactca
     5341 cacctcgttc gttaagttca ttaactaacg tgattaaatc ctccatgttc cgtcctagtc
     5401 tatctaatct ccaaacaaca atcgtatctc ctgacctcgc aaattcaatt gctttatcta
     5461 aaccaggtcg cttacttttt gaaccactca tatggtcatt aaatatcttt tcacaaccat
     5521 atgtatttaa tcgatcctcc tgtaaattca aattttgtaa tccagttgaa actcttgcat
     5581 aacctatttt caaaatacag acctcctata tacaccttta gtgtaccata acttgattac
     5641 gaggtctttt gtgaacatag attttttgtt gggtttttga acacataatt ctatgtaata
     5701 cttacttatt tagacaaaaa acaagagtgt acagaaaatg gttattttct ggacactctc
     5761 atctttaata atatatttta aatgtcatta acaaaactaa tttaataaga gtcaagtatg
     5821 gtttacatat gtattatgtt tgaaacatac ctctaattac tttttactaa tatcatttaa
     5881 aatgtctcgc aattcttcaa tttctttgtt atttaattct tcatttttcg caaaattcag
     5941 cactaaactt ttcatatccc ctccatacag tttattaaga aaggttttag cagttttcat
     6001 tttaatatcg tcttctttaa tatttgatga gtaaaaataa atattttctg atttgtatcg
     6061 ttttataatc tcttttttat atagtcttgt gattaatgtt ctaatcgttt tatcactaac
     6121 ttctttatat ttttgaattt caactacaat ttcattagct gatactgatt ttttatccca
     6181 tattatattc ataacatccc attcagccat agatatttca acttgcttat tggtcattta
     6241 aaacacccat tccttttaat attttttcac ttattaattc agcatttttc ccagacgggt
     6301 ttccatctga taaatgtgta gcaaaataat acttatcatg atttgtaatt acgtaaccta
     6361 caaaccaccc attattatac ttcccgttta ctatacctgt acctgttttc ccatacagtt
     6421 catacttttc atttttctta atcaataatg aagaagataa ttgattcttt gcttttttac
     6481 taaaatggtt attttgttcc atcatatttt taaaaactat tacttgttca agattagata
     6541 ttttcaaact atcttccatc caatagcttt tataacttcc caaattttca ttaccataat
     6601 ttaattgctt gagttgagcc gcagtatagt tctttggtat ttgattacta atacgttcga
     6661 agtaccaatt aactgaattt tgcattgctg tatttaaatc ttgttcctta ttccaagact
     6721 cgaaaagata atgtttatga ttccatgaca tacgtgaatt tttatcactt ataatatgac
     6781 ggtcaagtcc aaacagtgct aaataaattt tgtaagttga atcaggagaa tatctttttc
     6841 tactttcttt ttcattataa atatagtatt tgtctttctt catgctgtac ataacgaaag
     6901 atccactatt tgaaccaaaa tttttacttt catctaaaat ttggtaatcg ctttgtaagg
     6961 gctttttata attataatca gttaaggatt gccccattaa aaactggctt tgaattatca
     7021 tgataaaaaa agtaaaaata caaataaaaa ttagaattaa ttttgactgc tttttcagat
     7081 cggcttcttt tatattaatt aatctacttt tgagtaatga ttttttacca ttaaatgaat
     7141 ggcttaatat atttttgttg gaaaatgggg tttttaatac ggagtccata atagattccg
     7201 cataagtttt aaattcattt ttgttaatat tattaaggac aaatctatcg gcttctactt
     7261 cattgtcatg aattatcttt ctttttacaa tatgtactaa tggattgtaa ctcataataa
     7321 tagagaagat attaaagata attaaatgta aagtatctct atttttagca tgagcatatt
     7381 catgcagtat tatatatttt agtcttttat caattacact tttaaaatat gaactaggaa
     7441 tcaaaataat atatttccca taccaaaaag ttattggaga ttgaatagcc tctgcttttc
     7501 gaatcacaat atttttttta tattgatggt tgaaaagtat cgtatctatt ttattttttt
     7561 cattttcgtt tagataaagt gactgtttct ttaaatattt aagatataat aaggctttca
     7621 aaaatttaaa acttaaaata ataactaaaa ctatccaaat aactgtgcag atattatcaa
     7681 ttgaatccca attaaactta tggatatctg ttgtgaactc ttgaataggt ttggtggtat
     7741 ttatgttatg gttcaaatcg tgtgacttac tttcaactgt gggcgcttga ttattcacat
     7801 tattaaattt tataaaagag aatttaattg ggataaaagg aattaatcca gcaagcatag
     7861 ttagatacca aactttataa tttaaactat aattaaaata gcgttttaat atgtacctaa
     7921 aaaatactaa caatagaaat ataaaacaaa agcttactac gctcattatt agtaatttag
     7981 ccattttgac accttctttc aaatatttat aataaacaat tgacatcaat attacaattg
     8041 taatattatt gatttataaa aattacaact gtaatatcgg agggtttatt ttgaaaaagt
     8101 taatattttt aattgtaatt gctttagttt taagtgcatg taattcaaac agttcacatg
     8161 ccaaagagtt aaatgattta gaaaaaaaat ataatgctca tattggtgtt tatgctttaa
     8221 atactaaaag tggtaaggaa gtaaaattta attcagataa gagatttgcc tatgcttcga
     8281 cttcaaaagc gataaatagt gctattttgt tagaacaagt accttataat aagttaaata
     8341 aaaaagtaca tattaacaaa gatgatatag ttgcttattc tcctatttta gaaaaatatg
     8401 taggaaaaga tatcacttta aaagaactta ttgaggcttc aatgacatat agtgataata
     8461 cagcaaacaa taaaattata aaagaaatcg gtggaatcaa aaaagttaaa caacgtctaa
     8521 aagaactagg agataaagta acaaatccag ttagatatga gatagaatta aattactatt
     8581 caccaaagag caaaaaagat acttcaacgc ctgctgcttt cggcaagact ttaaataaac
     8641 ttatcgcaaa tggaaaatta agcaaaaaaa ataaaaattt cttacttgat ttaatgttta
     8701 ataataaaaa cggagacact ttaattaaag atggtgttcc aaaagactat aaggttgctg
     8761 ataaaagtgg tcaagcaata acatatgctt ctagaaatga tgttgctttt gtttatccta
     8821 agggccaatc tgaacctatt gttttagtca tttttacgaa taaagacaat aaaagtgata
     8881 agccaaatga taagttgata agtgaaaccg ccaagagtgt aatgaaggaa ttttaatatt
     8941 ctaaatgcat aataaatact gataacatct tatagtttgt attatatttt gtattatcgt
     9001 tgacatgtat aattttgata tcaaaaactg attttccctt tattattttc gagatttatt
     9061 ttcttaattc tctttaacaa actagaaata ttgtatatac aaaaaatcat aaataataga
     9121 tgaatagttt aattataggt gttcatcaat cgaaaaagca acgtatctta tttaaagtgc
     9181 gttgcttttt tctcatttat aaggttaaat aattctcata tatcaagcaa agtgacaata
     9241 gcattttaca agtatttttt attgttcgat tagggtaaac ctaaataata cataaattat
     9301 attacaatat gtttattata gaggctaaag tatcttagaa atttggatag taggtttttc
     9361 gggaataaaa gtatagttgg ctttaatata taattaagct aagctatcat ttatatttac
     9421 tcgattataa ttcgcacttc aactttttta taacgtaaaa attaaaacgt agttttattt
     9481 atctttagta atatcttttt aaacactaca gtttcttcat tagttaaatt agcgaagtaa
     9541 tgattattaa gttgataggc tttcttttct aatgttggcc ataagtcttt tgctttattt
     9601 gtactgttta ttagcacagt tcttctattt tcattatcag tttgacgtgt tattagatcc
     9661 tttttggaca tcttatctaa tattccagat attgttgaag gttctaaatt taaagtatta
     9721 ccaatcgctt taggtgtatt caaattacta ttaatcaagc aattcaaaac accatattct
     9781 gctggagtaa tattataggg acttaataaa cttttaaaat gtttaaaaac tctattctga
     9841 gaagtactca acaaataatt tatacaatta tctaattcca caactaaaac ctctcttaaa
     9901 tcattagtat tgactcgctt atcatatcat gataagtttt gtaggaaaat agttttgcaa
     9961 caaaaacata cttctacaaa acaattgtga aagaaggcta ataaatgttc aatgcggtag
    10021 tagtgagaaa aagtgcatca aatgttagtt ataaagtaga aaaagttgat gaatctcatt
    10081 tatcgaaggg tgatgtatta gtaaaagtgg tatactcttc aataaattat aaggatatgc
    10141 tagctttaca atataaaggc ggtgtaatta gagattatcc tatgattcct ggtatagatt
    10201 ttgcaggtat tgttgaatca agttcgaatg ataagtttaa agaaggcgat aatgtattag
    10261 ttactggtta tgatgttggc gtgacacata caggtggatt ttcagaatat gcacaagtgc
    10321 ctggagagtg gattgttcct attccccaag aaatgtctat taaagagtct atggtatatg
    10381 gcacagccgg ttttacggca gcattatcaa tttttgaact agaaaaatat ggaatgaata
    10441 tcaaatcaca acctgaaatt ttagtgtctg gggctacagg tggtgtgggc agtgttgcta
    10501 tacaaatttt acataaaatt ggatatgaaa atatcactgc tatcgtaaga aaagaaaagc
    10561 aaatagaaat cgcaaaaaaa ttaggtgcaa aacaagtaat aataattgaa gatgataata
    10621 aaccgcttaa aaaaggtatt tttgattatt tcttagatac agtggggagt aatgtaacat
    10681 tatacggttt aaaacgtcta aattatcaag gtgttgctac tgtatgtgga aatgtagcag
    10741 gaaattcact taacgctaat atattaccgt ttattcttag aggtattaaa ttaattggca
    10801 ttgattctgt atatgttgat cataatatcc gtgaagatat atggagtaag ttagcaaatg
    10861 aatggaatat aggaaattca cttctataca atgaaattgg atttgaagaa ttctataaaa
    10921 cgatagatca gcttttaaaa ggacaacatt taggaagaac tattttaaaa gtataagtgt
    10981 gagtattcat taatacattt actattaatt caatcatttt gcatttctct actaaccagt
    11041 gttataattt atataacgaa aatgattaac aattaatgca ccaatcccca cactattgca
    11101 gtagtgtggg gattttttcg atgctggctt ataaagtcgc ctattaatta tttgttgcgt
    11161 ttactaagcc aataagtata atacgcaaca gcacagccac tgatgactgg tgctatgatg
    11221 tgaacgaaaa tgattagcaa agtaatgcac ctcctctctt cgtcaattga cgcctgagag
    11281 ataggcgact ctattattat accatctgtg aatatacaag catatctact tccgataagt
    11341 cgtcttatgt tatataactt tgttttttat agtatcaaga caagaagaaa ctcgtttcaa
    11401 aaaccctcat gatttttaga gaaaaactct cttatttcat cgtctttaat aaaataatat
    11461 gccatctttc catctttata aaaatcaagt acctcatttt tatataaaag ccttaaatga
    11521 tgtgaagttg aagcaacact cattttcaat atcaaagaaa tatcacaaac acacaactca
    11581 tcttctttaa tcaaagataa tatgattttc aatttcttct catcacaaat tttttctaaa
    11641 atgttaagta atttcttaga tttatcatct tctaaaaaac ttaaagcatt gttaacttta
    11701 tcctcatgta cacagatcac atcacaagta ttttcataac tcatataaaa tcacacccta
    11761 aattaaaata taaatcctaa aattgtttga atagtgtcat tttcaataat aataaataaa
    11821 cctaaagcta tataaataat agccataatc caacgactaa atttctcaac aatttctcca
    11881 attcctggaa tattagctaa tttttgtgca gtaaacacca agaagaaaat taaaattaaa
    11941 aagacaaaca gagtaagtaa taaattagta acacttaatg tcacaaaata cggaacaaat
    12001 aaaccaatat tatcggcgcc acaacttgct atcgtaacaa ttgcaaccgt accaactaat
    12061 ttagacaatc ctttttcatt caattctttt ttagctctct tttctccttc acaatcatca
    12121 taaatagcca ctttaattcc aagataaatt ggtattaaac ccaataaacc taatatccac
    12181 ttttctggaa cataatttaa tacaaaagct aaaaacaaac taactaatat taaaataata
    12241 gaccctaaat attgaccaac ataaatatct ctatattctt ttctagtctt tgctctagca
    12301 aaaaatatta ataaaattac taataaatca actgctgtag caatataaag aacagcagca
    12361 gcaacaaccg tttgaatcat aatacacctc attcaaaaat atttttgaat gtattataac
    12421 ttatattttt aaataatcat aggtgcttta ttccaattgc tttattgacg ttgagcctcg
    12481 gaacccttaa caatcccaaa acttgtcgaa tggtcggctt aatagctcac gctatgccga
    12541 cattcgtctg caagtttagt taagggttct tctcaacatc aataaatttt ttcggcataa
    12601 atgcgtgtct atgcgtagac atggagacac ttcagaatta tggagtgatt acatgagttt
    12661 aactattttt ctttattcag ttttaggaag tttattagca aattatatct acgaaaaatc
    12721 ttcaaaataa ataacttttt cggttctact ttgtacactt tatctacctg gtagacctaa
    12781 ttgttattgc tttacaggtc taaaattcgt cgttataatc tagttaaatc ccgtaagggc
    12841 gcacttatac gtcggataaa tcgacatgtg caaaaacgta atcgaccttc gtcgattttt
    12901 ttatttcaaa attaaagaaa cggcttgaga tattccgagc agttataaaa attaatttgc
    12961 gttgaatatt gctactacat tcttgaaaaa gtgatgtaga tttatagccc ataacttttt
    13021 tgaattacat cgacgatacg gcgtcgaaag aaaaataaat agaccgtatg aaagaaaaag
    13081 ctacctcact ttatctgggg tagcttttat tttttatgcc cttattttga attttaagag
    13141 ggcattttaa agatttaggg gtgattcata tagttttata tctaaaactt atatatgctt
    13201 ttaaaacgca aatatgagcc aaataaatat atgctatttt caaaaacaaa aatttgagca
    13261 aaaacaataa ctatttttag acactgccca tttacatgca aattaaaaat tagcataaaa
    13321 ttctttaaaa cttccccacg tttttctaaa ttcctgtagg gcgtttttat caaaaatcaa
    13381 gacaagaaga aactcgttca cactcgtttc aaaaaaacaa gaaatctaat ctatacacct
    13441 accgttttcc aaccccctca aagcatacaa attaaaaaca aaattattca taatcttact
    13501 ttcttttaac aaaaacataa aaaccataaa tagacaaatt aactatcaaa ggcaataaac
    13561 agtataaaaa aaccacgaat aaatcttcat caacatctaa aataaaaaag aataaaacaa
    13621 ttaacaaaat actaattaac aaacctaaaa gtggcaaact ttttatatat ttttctaaat
    13681 tttcattcat aaaatagact cctttcaaaa atatgtttat aaatatatta aaataaatat
    13741 tgattttata aagcgcttac ttatacaatt aaaatatctt attatcttgg aggtatcaaa
    13801 tgaaaattat aaaattattt tcaataattt ccttgttcct actggtattt agcgcgaatt
    13861 tttctaatgc ttacgcaaat gaagaacaaa aaagttcttt actagaaaat caaaaagaaa
    13921 aattgaaaag caaaaacatc gaagtatcac aaatgaccaa gaaagaaata agttttctag
    13981 aacaattgca aaataaaaat gaagatatgc aaaaattcga aaagcaaatg aaaaaagaag
    14041 gatttaaaaa aataaagcta gaagacaaaa attctaaatt aaaatatcta gctacagaag
    14101 caaatgataa aaatgcatat ggctacatag ctaataacgc ttataaaaat gaaaaaacaa
    14161 aagaaattgt agtttctgaa acaatatatg ataactacaa caaaaaaatc acaaaattca
    14221 ttgccgaaaa aagaagtatg actgaaaaca aagagggaaa aatacttatt aacaaaaatt
    14281 acgttgaata taaggctgaa aaagttgata aaaacagacc ggtaacatat gcaggattca
    14341 aatggaacgg caaagcattc gcttgtagta tggctggact ttatgcatgt gctcactact
    14401 gtggagtatg ggcaatcgta aatccaatag ccggcggtgt atgtgaagca gtttgcggaa
    14461 ctgcatttgc agctggatgc tctgtaggtt gattttattc caattgtttt attgacgttg
    14521 agcctcggaa cccttaacaa tcccaaaact tgtcgaatgg tcggcttaat agctcacgct
    14581 atgccgacat tcgtctgcaa gtttagttaa gggttcttct caacatcaat aaattttttc
    14641 ggcataaata cgatgttcct tatttatcct cataaaaaac aatagctgaa atatataacc
    14701 aattactgtg tgtttgaatt tctaatacat gaatatcatt ctttaaaaac ctattaactt
    14761 gtttatctaa ttgacgatga gtaaaagtag cgaaagtttt aatcttcatg atatctctcc
    14821 ttttataaaa atagcaatcc ttattacaat attaaacact tttattttgg attttaagag
    14881 gcattttgaa gacttagagg caaatcatat aggttttgta cttaaaaatc tatacagtct
    14941 cttaaaacgc aaatatgagc caaataaata tatggtaatt tcacaaacaa aaatttcagc
    15001 aaaaccagtg actaattttt taacactgcc catttacatg caaattaaaa attagcataa
    15061 aatcctttaa aacttccaca tgtttttcta aattcctgca gggcgttttt tatcaaaaat
    15121 cgagaatttt taatttttct ctaaaaactc cgtaagagca taaggagaat ttgctatcat
    15181 tcaaaaatga taggtctggc aaagccagaa attccagggg ttttaaggta ttttaaagtg
    15241 atatcataca aagctgtact gtcttatttt tgtgacacaa tatattgcgt ttgtcttatt
    15301 tttgtgacac tacatacagc atttgtcaca aaaataagac agtacttttt tataaaaaat
    15361 caacaaaaaa gacattagtc aacactaatg tcttaaataa taattttgct tttcgaaatt
    15421 ccaaattgcg gtaattgaat gtgctttttc ttcttcgtct gttgttttat cttcatcact
    15481 tgcattaatc aaattaccat cttcgacatc gtctaagttt aaaattttat gcttttgttt
    15541 aagcaatcca ccataactta acatacgttt tcgatacaaa cctttttcta aatcacttac
    15601 aatttcttga tttttttcgt cgtcatcagt taaaaagtca gatgatttaa cggaatattt
    15661 tgatgtctct tcgagtgtta taaaatcatt tgaattattg attaaagata ttatattgtt
    15721 tcatgttttt acggcgcata taaagggcat gtgtttcttc aagttcagtt agaattgttt
    15781 gcattaaata agcttgcatt gacttgattg tttccttttg gcctttaact cccctatcat
    15841 gtatagcttt tttaagtctt tttaaagaag ttaatatttc atcctcaatg tcctctaaca
    15901 tgtaatgcat atcttcatgc cttgaattaa atgatttttt tgctttaaga ataacagcct
    15961 ttatgatttc taaatctcta taatcatatt ttaataaata attagttagt tgttctggga
    16021 attcttgcaa tagcatttct ttatcatcaa aattatgtgt aaattgattt gaatgatttg
    16081 aatgattact aatttcattt ttgtacttta tatcattcaa gtcattcata tcattattct
    16141 cagtatcatt aaagtcaatg tcattaaagt cagtatcatt agtgttcgat tttcgaactt
    16201 ctggacgttc gattttcgaa cttctggacg ttcgattttc gaacttctgg acgttcgatt
    16261 ttcgaacttc cttctcgccg taaggttcaa catcgttttc ttctttttct attttgtaaa
    16321 tatcacgttc tgtgacaata ggtttcatta aatatagaat atttggttta tttaaaccac
    16381 gtcgtttttg aatgagtaga ccatcgtttt ctaacccttt ttttattttt gttaactttt
    16441 cttttttaca atttaagatt tccattagct tttcatttga ataaacaaag taaatgttac
    16501 catcttcatc aacccagcta tttttaatag ataaatttaa gcgatcacgt aagatagcat
    16561 aggctatttt catatcatta gttagatttt tataattttc actggtaaag aatactttag
    16621 ggatttgata aaatctttct ttgtaatttt cttgcactgt aaaatattga ttttgcatga
    16681 caaaaaacct ctttccatat tttagtttgg taagaggtaa taaaacgttt ttatttagct
    16741 ttacatttat ttaatgattt aggtgcttgc actaagatat tattcattat ataatacaag
    16801 tatcgaaaat tatataaata aacagtttct aaacgtttta ttaccaaacc ccgactatta
    16861 ccagtagttg gggtttttgt tatattaagt ttattatagc actttaaata aacttataaa
    16921 agggaaaata tagctttatc aagggtttat aaacccttga taaatatcat aaacctttca
    16981 taaacccttg ataaaaaggt tgatggatgt ttatttttat ttattaatca ctttattatt
    17041 aagcattata agcttataat attttatcaa gggtttataa acattttata aagggttgat
    17101 gatatgaaaa gtgtgaaaaa gttgagtgaa gaattagggg ttagtaagca aacgattttt
    17161 aataatatta agcgattgaa tatagagaca ataaaacagg aaaacacttc gtttattaaa
    17221 gaagataccg atatagaaaa aatcattcaa agagtaaatg aaaataaaaa gaaatatggt
    17281 tttgaaagta ctactgaaga caaacaaaaa aaagggtcgg ataatattaa ttttgaatcg
    17341 aaaagcgatg ctcaaatagt agaaatcctt aaaaatcaga ttgatacttt aaataatcaa
    17401 attgaaaaac aagaaagtcg tcatgaaaca acaattgaat tttacagaaa agagttgcaa
    17461 gaaagatcaa aattgcttga aaatcagcaa gttctggcat tagagagtaa taaaaagatt
    17521 caaaaattag aaaatcaatt agaaaaagaa aaacacctta attatccctt tgatacatct
    17581 actaacacta gacaaaacgt tgatgcacaa gaaaaaacat atactactaa tcctgtaaat
    17641 attaacagag atcaggaaga aactaaagaa acagagattc aatataagga tatatctgga
    17701 agtcaaagcg acgaaagtac acaaggtgaa gaagcaaaaa aagaagacgt tccagctaat
    17761 ctaaatgaca atgatagtga tatagaagaa aagagtgaag aaacggaacc taaaaagggg
    17821 ttttggagtc gtttgtttgg tagctaaaat aattgattag gcactaaaag ttataaaatt
    17881 ttagtgtctt ttatatagtg agaacttctg gtaatcatcg attatgtaaa ctaaagtatt
    17941 tcaaataatt aactgtatta atactctcat catgattgcg ttataaacgt tcgttattga
    18001 gacaaaattt aatagtacta ctacacaaaa agagagtgcg aattcgcact ctctttttgt
    18061 gataaatgaa tggttaagaa aataattcat ccacagttgt atcaaacaat cttgccaact
    18121 taaatgctaa tgtcaatgta ggatcatatt tattgttttc tattgcatta atagtttgcc
    18181 tagacacttt taattcttta cttaaagttt cttgagaaat tcctttttgt tttctatatt
    18241 ctctaattct atttttcatt aatttaacct ttagatgtat attttttatt tgtagtatag
    18301 taattaaaca gcataagaaa tagtgctaca attataaaga aaatttctgg atattgagaa
    18361 aaccaagatc cttcaatact tggtgacaaa cctgtaaatt taagcactag tgtaaataac
    18421 atacaatata caatccaaat aaaactttta gccagtattt caataaacat tttacgttgt
    18481 ctttcatcgt atcgatcttg ttgtcctttt ttatctaatg tttctgaagg taaatatttg
    18541 ttagttatag ccgtccataa acaagaaaaa attaaaataa taataaaagg aattaaattc
    18601 attataacac ctcataaatg taaaaagtat ttgacattta tgagtgtaaa tatttttgat
    18661 acaaatgtca aatacttttt acattataat atattttaaa acaccttatt agtaaaacaa
    18721 ttactatata gaaagctgcg aactcgtact cttttttctt gtataattat taaaatctca
    18781 attcaataat atgttatgga atttgagaca ctgtgagaga cgctcatttg cattgacaat
    18841 caatttatca agataatccc ttatcatgtt taattctata aactgtttgt cttgtgatat
    18901 taacttcttt cgcaatctta ctaatcgctt tgccttcttc taacatttcc accacgcgat
    18961 gataaataac acgtttctgt gggtctttag catttggtga ataaagtaaa gggcgccctt
    19021 tatatacgcc tttttccttc gcaacttgaa tcccttgcgc ttgtcgacgt ttactttcat
    19081 ttctctcttg ttctgaaacc attgctaata tttgaatgat taaatctttc ataaacttat
    19141 ccagtaatgg attgccaatt acttcattca tcataggtaa gctggtaatc attaactgaa
    19201 cgtctttttc ttttaaataa ttcacagttt caataatttc atcatagtta cgtcctaaac
    19261 gatcaataga ttccacaacg aatcgatctc ccattctgac aaaattgagt gcttcttgaa
    19321 atacaggtct attttccact gactttcccg actgtttctc tgtaaagatt ttctccacac
    19381 caaacgtctt taaattatcc aattgtcttt ctaaattttg atctatcgat gatactctcg
    19441 cataacctat aatcattcat cttcactcca taataaatat acaccctaat catacgtttt
    19501 aattgttata atttcaacaa ttctttttgt atggttaggg tgtactcaaa gtgtacatat
    19561 ctataattaa aacttactaa aaataaatat agattttttc tttgtaacag aaccgttcat
    19621 ttgaaggtca tctctatcat aaatatttaa attaactaaa aattttaatc atctgtttaa
    19681 tacttatgaa atgtatttac ggtaggtatt aaaattgatg aaatttatat aagtgctttc
    19741 aatgaaaatg accgtttatt tatcctcctg atttaaggag ttagaaattt cgaaaacgat
    19801 tctttccatt tgttgcattt gttccatgtc cagatattta atacattata gaaaaccaaa
    19861 gaccatcact aattaaacgc agttttaaaa tttcatcagg attgccttcg tctttaaaat
    19921 gggcctcttt taatataagt tctactcttt catacctaac tctttcaatg ccatcgtttc
    19981 atacgccgat tctcctgatt ccatagcaaa ctcagcgata aacattggga atactgcatt
    20041 gagttctatt atatgctctt tcattcgtgg ccatatttca cctccagctt taccgtatgc
    20101 tgttataagt tgctctaatc cttcgtcgtc gaatacacga tggtgtccta taaagtccat
    20161 tgatgggtcg gagtgggttg cttcagtcca gtctatgaga cctgtgacgt ttgcttggtt
    20221 atctaccatt atatgtcctg gatgtaagtc cccatgtatc atggtcgcat gtcgaggcca
    20281 tagttcgtcg ttttctaacc attgtttcca tctgttccat aattcatctg atacgccata
    20341 agtttcttta actttattca ttcttctttg aaagtcattt tttatttctt gtatggtttt
    20401 gatatttata tgctgaacgt taatgttttc ttctggtatg ttgtgtaaat ctacgagtgt
    20461 ttcagctaat gtgttaataa agttttctgg taatggtttg tgttcaattt cccatacata
    20521 attttgtatt tctggatcta ttgtggctgc gggtttacct gtaagttttg ggtaagcaat
    20581 aaggtctttt gcatgtactt tccacttcgg tatttcaaat gaaacattct tctgtaagaa
    20641 gtctaccgtt tgtttttcgg gttttgttcg tttataaacg tcaggtcttc ttggtagtct
    20701 caaaacccat tctactccat gtttatcttt tccaaatgca acttgaaaat caagtcccga
    20761 ttcattcaat gagattgttt gaggttggat gtgtaattga tatttttctg cacatttaat
    20821 aatttcatta tgtcgagtca ttttattgga tccttatttc tattatattt ttcttgtgaa
    20881 cgtatttttt atattgatat aaatgaacct aatattcaat ataaattagt gtatagtttt
    20941 taagttatat catgaagaga ttgtcctgtt aattcccatt ttttatctga tacatgttta
    21001 acaaaccttg tatcatgtga tgtaaacaaa atgattccag gatatttatt cataaacatt
    21061 tctaatgctt ctaatgtttt aatatctaaa aaattagttg gttcatccaa aattaacata
    21121 ttcgctttcg ttgaaaataa tactgctaac gataatttcg ttctttcccc accactcaaa
    21181 acattacaag aacgatcaag tgcttcattt aaacccaagt tatttaaaat agctctactg
    21241 aatgattctg atgaatccgt ttcatccatt aaatattgca ataatgaaac gtcacgcatg
    21301 tcttcataag caagttgacg atagtatgcc atttgcactt taggagaaca atcaattccc
    21361 tctatttggt ggtaaatagc ttcaagtaaa gttgtcttac ctacaccatt tgcacctacg
    21421 agcgctatat ttttgccata tggtatttgg aatcgtactt gtgttagcag tttttgactt
    21481 cctttaacca atgttagatt ttgtgcaatg attggataat tattatggat atcataaatt
    21541 ttattttgtg ggaaattgaa ttcatgataa ctttgtggtt tttcaacttc ttccaaatgt
    21601 tccattcttt tttcaatatg cttagcttgt ttttgagcag ccttctcaac cgtgcctttt
    21661 tgttttgatg cacttaaacg atctggtgct atacttttgt ttttttgttt tgatgatgct
    21721 tgtgccattt gttgcgcttg atttcgttta gctttactgg cttgggacaa tctttgtttt
    21781 tcacttatat actgttcata ttgacgttgt tgttctaact gttcttgttc atattgattt
    21841 tgatactgtg tgtaattacc tttaaacact cttattgtgc catcttcttg tatatcccaa
    21901 attgtgtcag caatttggtc tataagtgct ctatcatgac ttactataat taaagtacca
    21961 tagtaatatt ttaaaatatt tttcagataa tctttaccaa ttttatccaa gtgatttgta
    22021 ggttcatcta aaagtaatat cggactataa tttgatatga cattagctaa tttatatttt
    22081 gctttttcac caccactcat actgtcggtt gtatgcatag gtatatggag ttcactcatt
    22141 aaactaccgt ctaacgtgtt aaaatcattt tccacatcca tgttaagctg ttcaaaatat
    22201 tgaatttcgc caaccgtttc aactgttcca gattctggtt ttgttttttg agcaatcata
    22261 tttagtaatg tggttttgcc agtaccatta cccccaataa gtgctatttt ttcaaattgg
    22321 taagcgtaaa gatgaccgat gttaagtgat cgtaaatctg tcaatttatg attgatttgg
    22381 ttaaatttaa ttgtatattg ttccatattt atacactcct tgtatattta aaggacgtgt
    22441 acgcaaaaaa atgagacagg ctactcccgt ctcattcaca ttacactttc aaacacttaa
    22501 aaatttatta tgatgtttta gtatttgaaa gcgtttatta ttcctatcga aggataaaaa
    22561 atgacataag tcatcctatg agtgtgtatt gcggacaagc ctttttgaat taatttagtt
    22621 ttgtattcaa aaaggtttat ttgagtctca tagaagctgt cattttaatc ctccttcatc
    22681 gataaaatag taatgttaat ataacatttt gttggttttt ttacaatata tctctaagta
    22741 gaaagattat ataacaaaag tataaaaata caattttaga ttgattatac atctccttaa
    22801 tttagagtgt actcataaaa tacggttctg ttgcaaagtt gaatttataa tataatttta
    22861 acaaaaagga gtcttctgta tgaactattt cagatataaa caatttaaca aggatgttat
    22921 cactgtagcc gttggctact atctaagata tgcattgagc tatcgtgata tatctgaaat
    22981 attaagagaa cgtggtgtaa acgttcatca ttcaacgatc taccgttggg ttcaagaata
    23041 tgccccaatt ttatatcaaa tttggaagaa aaagcataaa aaagcttatt acaaatggcg
    23101 tattgatgag acgtatatca aaataaaagg aaaatggagc tatttatatc gtgccattga
    23161 tacagaggga catacattag atatttggtt gcgtaagcaa cgagataatc attcagcata
    23221 tgcgtttatc aaacgtctca ttaaacaatt tggtaagcct caaaaggtag ttacagatca
    23281 ggcaccttca acgaaggcag caatggctaa aataattaaa gcttttaaac ttaaacctga
    23341 ctgtcattgt acatcgaaat atctgaataa cctcattgag caagatcacc gtcatattaa
    23401 agtaagaaag acaagatatc aaagtatcaa tacggcaaag aatactttaa aaggtattga
    23461 atgtatttac gctctatata aaaagaaccg taggtctctt cagatctacg gattttcccc
    23521 atgccacgaa attagcatca tgctagcaag ttaaacgaac actgacatga tatattagtg
    23581 attagctata ttttttactt tgcaacagaa ccagccattt aatatgactg ttacaattac
    23641 taagattcaa gcactattac gccgcacgta tgatttcacc actcaagtta ataatttaac
    23701 agtagatgat tgcgagttac tacttgatgc agcaaagctt aaatttaatg aagaaaccat
    23761 agacctgaca cacactgaat tgcaaatcat gcatagctta ttccagaaca agggcaaatt
    23821 cgtcagtcgt aatgcgttaa tcgaaaaatg ctgggaatca gaacacttca ttgatgacaa
    23881 tacgcttgct gtcaacatta cacgtttacg caaaaagcta caaaaactag gacttacaga
    23941 ttttatcgaa acgaagaaaa atgtcggata tcgtgtaggt gacgtatgaa tttcttgaaa
    24001 tcaatccaac gtgaaattta tattgtcatc cttacttgtg ctttattcta ctttatatta
    24061 ttcatgtata atgtgccgat gcaagcatat atgattggtc taggtattgt attgtttgtt
    24121 tcaatgattt actggggtat ccattacatg aactttaaaa aagaataaac actacaggaa
    24181 cagaacgaag atttaagaat cgaaaaccat aaacttcgta atgactttat taactaccaa
    24241 agtgagttag agtcatattt tttaatgtgg gtgcatcaaa tcaagacacc gattacagca
    24301 tcaaagttac tgcttgaaga tcctgatgaa cacgtgattt ctaacgtgcg taatgaagtc
    24361 ttacaaattg ataattacac gaatcttgca ctgaactatt tgaaactcat gaaccaaaag
    24421 acatacatgg tctttatgga agtgagtgta gatgaattaa ttcgaccact gattaaacgt
    24481 tatgcgatac agtttattca tcatcaaaca aagttgcatt atgagaaaag tgaagcggtt
    24541 atattaacag atgccaaatg ggcatcaatt atgattgagc aaatattaaa caatgcatta
    24601 aaatatgcac gtggcaaaga tgtgtggatt acgtttgacg aaaatacaaa gaaattatca
    24661 atccgagata acggtatcgg cattaatgcg agtgatttac cgaaaatctt tgataaaggt
    24721 ttctcgggct ataacggtag aataagtgag aaatcaagcg gtattggttt atatattgtc
    24781 agcacaatct caaagcgctt aggccataaa gtaagtgcta catctacatt aaacgatggt
    24841 tcaatattca ccattcaatt taaataactc caatctttca tttttgtaag attagcggct
    24901 gtttttgtaa gaatagataa aggcagcctt ttctaatcgc gcgtaagata aaggtaacaa
    24961 caaactaaga aaggtgccag aggtgaaaaa tttgaataat ataattgaaa taaataactt
    25021 aacaaagcaa tatggaagtc agatagcagt taataatttg agtataactg ttgaaagtgg
    25081 acaaatttat ggttttttag gaagaaatgg tgcaggcaaa acaactacta taagaatgct
    25141 tttaggctta attaaaccta cgaaaggtaa tattaaaata tttgaaaaag agttcgaaag
    25201 taataaaact gaaattttaa aaaatattgg tgctatggtt gaaacgccag gtttttatag
    25261 taatttgaca gctaaagaga acttaactat aaatgctaaa atattaggta tacaaaaaga
    25321 aaatgcaatt gaagaagtgt tagaaatagt aggactagct tctgaaaaag taaaattgtt
    25381 taaaaattat tctttaggta tgaagcaacg tttagggatt gcgagagctt tattgcacaa
    25441 tcccgaatta ttgatacttg atgagccgac gaatggatta gatcctattg gcataaaaga
    25501 aattagaaag ttgattaagg atctggctca atctagaaat ataaccattt taatttcaag
    25561 tcatatattg tcagaaatag agcagttagt agacaaggtg ggtattattc ataacggagt
    25621 tttgttagaa gaaattatgt atgaagattt aaaaaaaaag aacagacaat ttataagtat
    25681 atcagtatca gatgaagaaa aagttgcatg tttgttggaa actaacttcg gaatttatga
    25741 ctataaaatt aaagaaaatg gcgaatttaa aatttattca catattgata gacaacaaga
    25801 aattaataga ttattagtat taaacaatat tgatgttttc cagatgagag tgatagaaga
    25861 taatctagaa acttatttcg aagacttagt aggaggtggc acaattggat aatctactcc
    25921 gtacagaatt tattaagtta aaaagatcat atatgtttct aataagtatt ttaggtacat
    25981 gcgtagcacc ttttatggtg gttgtagctt cttttattag tatgcggacg aaagtaccga
    26041 ctcctaatat tgtatttaaa cagttatttg aagaagtcag tttatatcat atgctaatta
    26101 ttggacctcc tctatatggg gttataatag cctatttgtt tggaagagaa tatatagaag
    26161 atactttaaa aaacttatta attataccta tatctagaga aagtttttta gtaagtaaaa
    26221 taatattatt attcttgtgg attcaaacac tatctgttat tgcatggttg ctaactttaa
    26281 tgctaggtat gctattgcat tttcaagggt taagccagag tttaataatt gattcattct
    26341 ttacatttgt tattggcgga gtgttattat ggatattatc tccaccaata attattttgt
    26401 cgatatattt taaaaattat gttcccacaa ttgttttaac cataataatt actttgataa
    26461 atttaatgac tgctaattct gaacatagag gattatttcc ttgggctgca gttggagaca
    26521 tatctagagg aacattacct aatacttatc catttctatt atctttaatt atcataattg
    26581 ttacatctat attcagtgta attatattat tctcatactt taaaaaaact gatataagtt
    26641 aaaaggagga gaaaaatggg ttttatagag cagattaaag catttatttt aggtgtagtt
    26701 gaagggttga cagaatttgc tccagtatca tcaacaggtc atatgattat tgttgatgat
    26761 atgtggttaa acactgctga cgatttagga agtgcgtctg caactacttt taaggtggta
    26821 atacagttag gaggttctgt tgcaaagttg aatttataat ataattttaa caaaaaggag
    26881 tcttctgtat gaactatttc agatataaac aatttaacaa ggatgttatc actgtagccg
    26941 ttggctacta tctaagatat gcattgagct atcgtgatat atctgaaata ttaagagaac
    27001 gtggtgtaaa cgttcatcat tcaacgatct accgttgggt tcaagaatat gccccaattt
    27061 tatatcaaat ttggaagaaa aagcataaaa aagcttat
//
