LOCUS       NZ_CP014370            27068 bp    DNA     circular CON 08-MAY-2024
DEFINITION  Staphylococcus aureus strain USA300-SUR3 plasmid pUSA04-1-SUR3,
            complete sequence.
ACCESSION   NZ_CP014370
VERSION     NZ_CP014370.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN04497597
            Assembly: GCF_003595405.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 27068)
  AUTHORS   Sabat,A.J., Hermelijn,S.M., Akkerboom,V., Juliana,A., Degener,J.E.,
            Grundmann,H. and Friedrich,A.W.
  TITLE     Complete-genome sequencing elucidates outbreak dynamics of CA-MRSA
            USA300 (ST8-spa t008) in an academic hospital of Paramaribo,
            Republic of Suriname
  JOURNAL   Sci Rep 7, 41050 (2017)
   PUBMED   28106148
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27068)
  AUTHORS   Sabat,A.J., Hermelijn,S., Akkerboom,V., Degener,J.E., Grundmann,H.
            and Friedrich,A.W.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-FEB-2016) Medical Microbiology, University Medical
            Center Groningen, Hanzeplein 1, Groningen 9700 RB, The Netherlands
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SeqMan NGen v. 12.1.0
            Genome Coverage                   :: missing
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003595405.1-RS_2024_05_07
            Annotation Date                   :: 05/07/2024 04:06:08
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,998
            CDSs (total)                      :: 2,917
            Genes (coding)                    :: 2,830
            CDSs (with protein)               :: 2,830
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 46 of 87
            Pseudo Genes (incomplete)         :: 43 of 87
            Pseudo Genes (internal stop)      :: 19 of 87
            Pseudo Genes (multiple problems)  :: 20 of 87
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP014370.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..27068
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="USA300-SUR3"
                     /isolation_source="Wound fluid"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="pUSA04-1-SUR3"
                     /geo_loc_name="Suriname: Paramaribo"
                     /lat_lon="5.866667 N 55.166667 W"
                     /collection_date="2013-04-24"
                     /collected_by="Sandra Hermelijn"
     gene            join(26859..27068,1..465)
                     /locus_tag="AYM15_RS15470"
                     /old_locus_tag="AYM15_15100"
     CDS             join(26859..27068,1..465)
                     /locus_tag="AYM15_RS15470"
                     /old_locus_tag="AYM15_15100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105956.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            <606..1241
                     /locus_tag="AYM15_RS15475"
                     /pseudo=""
     CDS             <606..1241
                     /locus_tag="AYM15_RS15475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009251744.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /name="aminoglycoside 6-adenylyltransferase"
     gene            1238..1768
                     /gene="sat4"
                     /locus_tag="AYM15_RS15480"
                     /old_locus_tag="AYM15_15115"
     ARG             1239..1765
                     /name="sat4"
                     /gene="sat4"
                     /gene_name="streptothricin N-acetyltransferase Sat4"
                     /tool="amrfinderplus"
                     /drug_class="STREPTOTHRICIN"
                     /identity="97.78"
                     /coverage="100.0"
     gene            1861..2655
                     /gene="aph(3')-IIIa"
                     /locus_tag="AYM15_RS15485"
                     /old_locus_tag="AYM15_15120"
     ARG             1862..2652
                     /name="aph(3')-IIIa"
                     /gene="aph(3')-IIIa"
                     /gene_name="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            3137..>3612
                     /locus_tag="AYM15_RS15980"
                     /old_locus_tag="AYM15_15125"
                     /pseudo=""
     CDS             3137..>3612
                     /locus_tag="AYM15_RS15980"
                     /old_locus_tag="AYM15_15125"
                     /inference="COORDINATES: protein motif:HMM:NF024676.4"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /name="WYL domain-containing protein"
     gene            complement(3671..4345)
                     /locus_tag="AYM15_RS15505"
                     /old_locus_tag="AYM15_15130"
     CDS             complement(3671..4345)
                     /locus_tag="AYM15_RS15505"
                     /old_locus_tag="AYM15_15130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105991.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            4607..4792
                     /locus_tag="AYM15_RS15700"
                     /old_locus_tag="AYM15_15135"
     CDS             4607..4792
                     /locus_tag="AYM15_RS15700"
                     /old_locus_tag="AYM15_15135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001037130.1"
                     /translation="MNKLEKWSLVFIIFTFLSSLALLYFKYNFSSVMPVLSLSILTILI
                     LLTSIITVVSVNDEDT"
                     /name="hypothetical protein"
     gene            complement(5015..5593)
                     /locus_tag="AYM15_RS15510"
                     /old_locus_tag="AYM15_15140"
     CDS             complement(5015..5593)
                     /locus_tag="AYM15_RS15510"
                     /old_locus_tag="AYM15_15140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690624.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690637.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLNLLKTLYDNGTPI
                     KTIAEQWQVSRTTIYRYLNKLEAKENKNK"
                     /name="recombinase family protein"
     gene            complement(5857..6237)
                     /gene="blaI"
                     /locus_tag="AYM15_RS15515"
                     /old_locus_tag="AYM15_15145"
     ARG             complement(5861..6237)
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="98.41"
                     /coverage="100.0"
     gene            complement(6227..7984)
                     /gene="blaR1"
                     /locus_tag="AYM15_RS15520"
                     /old_locus_tag="AYM15_15150"
     ARG             complement(6231..7984)
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.38"
                     /coverage="100.0"
     gene            8091..8936
                     /gene="blaZ"
                     /locus_tag="AYM15_RS15525"
                     /old_locus_tag="AYM15_15155"
     ARG             8092..8933
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(9462..9881)
                     /locus_tag="AYM15_RS15535"
                     /old_locus_tag="AYM15_15160"
     CDS             complement(9462..9881)
                     /locus_tag="AYM15_RS15535"
                     /old_locus_tag="AYM15_15160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418034.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_000418035.1"
                     /translation="MELDNCINYLLSTSQNRVFKHFKSLLSPYNITPAEYGVLNCLINS
                     NLNTPKAIGNTLNLEPSTISGILDKMSKKDLITRQTDNENRRTVLINSTNKAKDLWPTL
                     EKKAYQLNNHYFANLTNEETVVFKKILLKINKTTF"
                     /name="MarR family transcriptional regulator"
     gene            10005..10976
                     /locus_tag="AYM15_RS15540"
                     /old_locus_tag="AYM15_15165"
     CDS             10005..10976
                     /locus_tag="AYM15_RS15540"
                     /old_locus_tag="AYM15_15165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="WP_000481279.1"
                     /translation="MFNAVVVRKSASNVSYKVEKVDESHLSKGDVLVKVVYSSINYKDM
                     LALQYKGGVIRDYPMIPGIDFAGIVESSSNDKFKEGDNVLVTGYDVGVTHTGGFSEYAQ
                     VPGEWIVPIPQEMSIKESMVYGTAGFTAALSIFELEKYGMNIKSQPEILVSGATGGVGS
                     VAIQILHKIGYENITAIVRKEKQIEIAKKLGAKQVIIIEDDNKPLKKGIFDYFLDTVGS
                     NVTLYGLKRLNYQGVATVCGNVAGNSLNANILPFILRGIKLIGIDSVYVDHNIREDIWS
                     KLANEWNIGNSLLYNEIGFEEFYKTIDQLLKGQHLGRTILKV"
                     /name="oxidoreductase"
     gene            complement(11148..11240)
                     /locus_tag="AYM15_RS15545"
     CDS             complement(11148..11240)
                     /locus_tag="AYM15_RS15545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(11397..11744)
                     /locus_tag="AYM15_RS15550"
                     /old_locus_tag="AYM15_15170"
     CDS             complement(11397..11744)
                     /locus_tag="AYM15_RS15550"
                     /old_locus_tag="AYM15_15170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119690.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNHEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            complement(11763..12380)
                     /gene="cadD"
                     /locus_tag="AYM15_RS15555"
                     /old_locus_tag="AYM15_15175"
     ARG             complement(11767..12380)
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(13496..13690)
                     /locus_tag="AYM15_RS15560"
                     /old_locus_tag="AYM15_15180"
     CDS             complement(13496..13690)
                     /locus_tag="AYM15_RS15560"
                     /old_locus_tag="AYM15_15180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001004925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001004925.1"
                     /translation="MNENLEKYIKSLPLLGLLISILLIVLFFFILDVDEDLFVVFLYCL
                     LPLIVNLSIYGFYVFVKRK"
                     /name="hypothetical protein"
     gene            13800..14492
                     /locus_tag="AYM15_RS15565"
                     /old_locus_tag="AYM15_15185"
     CDS             13800..14492
                     /locus_tag="AYM15_RS15565"
                     /old_locus_tag="AYM15_15185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative immunity/bacteriocin fusion bifunctional
                     protein"
                     /protein_id="WP_000691527.1"
                     /translation="MKIIKLFSIISLFLLVFSANFSNAYANEEQKSSLLENQKEKLKSK
                     NIEVSQMTKKEISFLEQLQNKNEDMQKFEKQMKKEGFKKIKLEDKNSKLKYLATEANDK
                     NAYGYIANNAYKNEKTKEIVVSETIYDNYNKKITKFIAEKRSMTENKEGKILINKNYVE
                     YKAEKVDKNRPVTYAGFKWNGKAFACSMAGLYACAHYCGVWAIVNPIAGGVCEAVCGTA
                     FAAGCSVG"
                     /name="putative immunity/bacteriocin fusion bifunctional
                     protein"
     gene            complement(14660..14809)
                     /locus_tag="AYM15_RS15810"
     CDS             complement(14660..14809)
                     /locus_tag="AYM15_RS15810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000695366.1"
                     /translation="MKIKTFATFTHRQLDKQVNRFLKNDIHVLEIQTHSNWLYISAIVF
                     YEDK"
                     /name="hypothetical protein"
     gene            complement(15356..>15645)
                     /locus_tag="AYM15_RS15570"
                     /pseudo=""
     CDS             complement(15356..>15645)
                     /locus_tag="AYM15_RS15570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009384749.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            complement(15665..16648)
                     /locus_tag="AYM15_RS15575"
                     /old_locus_tag="AYM15_15190"
     CDS             complement(15665..16648)
                     /locus_tag="AYM15_RS15575"
                     /old_locus_tag="AYM15_15190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_031871915.1"
                     /translation="MQNQYFTVQENYKERFYQIPKVFFTSENYKNLTNDMKIAYAILRD
                     RLNLSIKNSWVDEDGNIYFVYSNEKLMEILNCKKEKLTKIKKGLENDGLLIQKRRGLNK
                     PNILYLMKPIVTERDIYKIEKEENDVEPYGEKEVRKSNVQKFENRTSRSSIFERPEVRK
                     SNTNDTDFNDIDFNDTENNDMNDLNDIKYKNEISNHSNHSNQFTHNFDDKEMLLQEFPE
                     QLTNYLLKYDYRDLEIIKAVILKAKKSFNSRHEDMHYMLEDIEDEILTSLKRLKKAIHD
                     RGVKGQKETIKSMQAYLMQTILTELEETHALYMRRKNMKQYNIFNQ"
                     /name="replication initiator protein A"
     gene            17074..17817
                     /locus_tag="AYM15_RS15580"
                     /old_locus_tag="AYM15_15195"
     CDS             17074..17817
                     /locus_tag="AYM15_RS15580"
                     /old_locus_tag="AYM15_15195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843732.1"
                     /translation="MKSVKKLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESTTEDKQKKGSDNINFESKSDAQIVEILKNQIDTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNTR
                     QNVDAQEKTYTTNPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAKKEDVPANLND
                     NDSDIEEKSEETEPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     gene            complement(18044..18229)
                     /locus_tag="AYM15_RS15585"
                     /old_locus_tag="AYM15_15200"
     CDS             complement(18044..18229)
                     /locus_tag="AYM15_RS15585"
                     /old_locus_tag="AYM15_15200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011276570.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000797248.1"
                     /translation="MKNRIREYRKQKGISQETLSKELKVSRQTINAIENNKYDPTLTLA
                     FKLARLFDTTVDELFS"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(18234..18572)
                     /locus_tag="AYM15_RS15590"
                     /old_locus_tag="AYM15_15205"
     CDS             complement(18234..18572)
                     /locus_tag="AYM15_RS15590"
                     /old_locus_tag="AYM15_15205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001049146.1"
                     /translation="MNLIPFIIILIFSCLWTAITNKYLPSETLDKKGQQDRYDERQRKM
                     FIEILAKSFIWIVYCMLFTLVLKFTGLSPSIEGSWFSQYPEIFFIIVALFLMLFNYYTT
                     NKKYTSKG"
                     /name="hypothetical protein"
     gene            complement(18818..19426)
                     /locus_tag="AYM15_RS15595"
                     /old_locus_tag="AYM15_15210"
     CDS             complement(18818..19426)
                     /locus_tag="AYM15_RS15595"
                     /old_locus_tag="AYM15_15210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002474535.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000583528.1"
                     /translation="MIIGYARVSSIDQNLERQLDNLKTFGVEKIFTEKQSGKSVENRPV
                     FQEALNFVRMGDRFVVESIDRLGRNYDEIIETVNYLKEKDVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRV
                     IYHRVVEMLEEGKAISKIAKEVNITRQTVYRIKHDKGLS"
                     /name="recombinase family protein"
     gene            complement(19912..20811)
                     /locus_tag="AYM15_RS15600"
                     /old_locus_tag="AYM15_15215"
     CDS             complement(19912..20811)
                     /locus_tag="AYM15_RS15600"
                     /old_locus_tag="AYM15_15215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mph(C) family macrolide 2'-phosphotransferase"
                     /protein_id="WP_000196697.1"
                     /translation="MTRHNEIIKCAEKYQLHIQPQTISLNESGLDFQVAFGKDKHGVEW
                     VLRLPRRPDVYKRTKPEKQTVDFLQKNVSFEIPKWKVHAKDLIAYPKLTGKPAATIDPE
                     IQNYVWEIEHKPLPENFINTLAETLVDLHNIPEENINVQHINIKTIQEIKNDFQRRMNK
                     VKETYGVSDELWNRWKQWLENDELWPRHATMIHGDLHPGHIMVDNQANVTGLIDWTEAT
                     HSDPSMDFIGHHRVFDDEGLEQLITAYGKAGGEIWPRMKEHIIELNAVFPMFIAEFAME
                     SGESAYETMALKELGMKE"
                     /name="Mph(C) family macrolide 2'-phosphotransferase"
     gene            complement(20910..22376)
                     /gene="msr(A)"
                     /locus_tag="AYM15_RS15605"
                     /old_locus_tag="AYM15_15220"
     ARG             complement(20914..22376)
                     /name="msr(A)"
                     /gene="msr(A)"
                     /gene_name="ABC-F type ribosomal protection protein Msr(A)"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE/STREPTOGRAMIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            22850..23524
                     /locus_tag="AYM15_RS15610"
                     /old_locus_tag="AYM15_15225"
     CDS             22850..23524
                     /locus_tag="AYM15_RS15610"
                     /old_locus_tag="AYM15_15225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="WP_001105960.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            <23582..23959
                     /locus_tag="AYM15_RS15615"
                     /old_locus_tag="AYM15_15230"
                     /pseudo=""
     CDS             <23582..23959
                     /locus_tag="AYM15_RS15615"
                     /old_locus_tag="AYM15_15230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019834602.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]; GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /name="response regulator transcription factor"
     gene            23956..24837
                     /locus_tag="AYM15_RS15620"
                     /old_locus_tag="AYM15_15240"
                     /pseudo=""
     CDS             23956..24837
                     /locus_tag="AYM15_RS15620"
                     /old_locus_tag="AYM15_15240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015581923.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0000155 - phosphorelay sensor kinase activity [Evidence
                     IEA]; GO:0004673 - protein histidine kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /name="sensor histidine kinase"
     gene            24953..25882
                     /locus_tag="AYM15_RS15625"
                     /old_locus_tag="AYM15_15245"
     CDS             24953..25882
                     /locus_tag="AYM15_RS15625"
                     /old_locus_tag="AYM15_15245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000074567.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016887 - ATP hydrolysis activity [Evidence IEA];
                     GO:0042626 - ATPase-coupled transmembrane transporter
                     activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000793446.1"
                     /translation="MKNLNNIIEINNLTKQYGSQIAVNNLSITVESGQIYGFLGRNGAG
                     KTTTIRMLLGLIKPTKGNIKIFEKEFESNKTEILKNIGAMVETPGFYSNLTAKENLTIN
                     AKILGIQKENAIEEVLEIVGLASEKVKLFKNYSLGMKQRLGIARALLHNPELLILDEPT
                     NGLDPIGIKEIRKLIKDLAQSRNITILISSHILSEIEQLVDKVGIIHNGVLLEEIMYED
                     LKKKNRQFISISVSDEEKVACLLETNFGIYDYKIKENGEFKIYSHIDRQQEINRLLVLN
                     NIDVFQMRVIEDNLETYFEDLVGGGTIG"
                     /name="ABC transporter ATP-binding protein"
     gene            25875..26612
                     /locus_tag="AYM15_RS15630"
                     /old_locus_tag="AYM15_15250"
     CDS             25875..26612
                     /locus_tag="AYM15_RS15630"
                     /old_locus_tag="AYM15_15250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000369394.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="WP_000369394.1"
                     /translation="MDNLLRTEFIKLKRSYMFLISILGTCVAPFMVVVASFISMRTKVP
                     TPNIVFKQLFEEVSLYHMLIIGPPLYGVIIAYLFGREYIEDTLKNLLIIPISRESFLVS
                     KIILLFLWIQTLSVIAWLLTLMLGMLLHFQGLSQSLIIDSFFTFVIGGVLLWILSPPII
                     ILSIYFKNYVPTIVLTIIITLINLMTANSEHRGLFPWAAVGDISRGTLPNTYPFLLSLI
                     IIIVTSIFSVIILFSYFKKTDIS"
                     /name="ABC transporter permease"
     gene            26626..>26802
                     /locus_tag="AYM15_RS15635"
                     /old_locus_tag="AYM15_15255"
                     /pseudo=""
     CDS             26626..>26802
                     /locus_tag="AYM15_RS15635"
                     /old_locus_tag="AYM15_15255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499250.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016311 - dephosphorylation [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /name="undecaprenyl-diphosphate phosphatase"
     ARG             complement(19916..20811)
                     /name="mph(C)"
                     /gene="mph(C)"
                     /gene_name="Mph(C) family macrolide 2'-phosphotransferase"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(20911..22376)
                     /name="msrA"
                     /gene="msrA"
                     /gene_name="msr-type ABC-F protein"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; streptogramin
                     antibiotic; streptogramin B antibiotic"
                     /identity="98.36"
                     /coverage="100.0"
     ARG             complement(19913..20811)
                     /name="mphC"
                     /gene="mphC"
                     /gene_name="macrolide phosphotransferase (MPH)"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="98.66"
                     /coverage="100.0"
     ARG             1251..1768
                     /name="SAT-4"
                     /gene="SAT-4"
                     /gene_name="streptothricin acetyltransferase (SAT)"
                     /tool="rgi"
                     /drug_class="nucleoside antibiotic"
                     /identity="97.16"
                     /coverage="95.56"
     ARG             8092..8936
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     ARG             643..944
                     /name="aad(6)"
                     /gene="aad(6)"
                     /gene_name="ANT(6)"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="99.0"
                     /coverage="36.23"
     Typing          complement(15153..15300)
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="5.980000000000001e-72"
     Typing          complement(15359..15534)
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="92.697"
                     /coverage="94.0"
                     /evalue="1.04e-65"
     Typing          complement(15666..16648)
                     /name="rep_cluster_2100"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.289"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          17075..17817
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 tacaaatggc gtattgatga gacgtatatc aaaataaaag gaaaatggag ctatttatat
       61 cgtgccattg atacagaggg acatacatta gatatttggt tgcgtaagca acgagataat
      121 cattcagcat atgcgtttat caaacgtctc attaaacaat ttggtaaacc tcaaaaggta
      181 attacagatc aggcaccttc aacgaaggta gcaatggtta aagtaattaa agcttttaaa
      241 cttaaacctg actgccattg tacatcgaaa tatctgaata acctcattga gcaagatcac
      301 cgtcatatta aagtaagaaa gacaaggtat caaagtatca atacagcaaa gaatacttta
      361 aaaggtattg agtgtattta cgctctatat aaaaagaacc gcaggtctct tcagatctac
      421 ggattttcgc catgccacga aattagcatc atgctagcaa gttaaacgaa cactgacatg
      481 atatattagt gattagctat attttttact ttgcaacaga accatcattt ttattaaaat
      541 actcttttgt aaaatctttc tgctcttcaa tgtatttaat ttctttacct ctaaatctat
      601 tatagctatt tgatgattac aataaaattg atcttacctt attgcccttg gaagagttag
      661 ataattacct aaagggcgat aaattaataa aggttctaat tgataaagat tgtagaatta
      721 aaagggacat agttccgact gatatagatt atcatgtaag aaagccaagc gcaagggagt
      781 atgatgattg ctgcaatgaa ttttggaatg taacacctta tgttattaaa ggattgtgcc
      841 gtaaggaaat tttatttgct attgatcatt ttaatcagat tgttcgccat gagctgctga
      901 gaatgatatc atggaaggtc ggcatcgaaa caggctttaa atgaagtgta ggcaagaact
      961 ataagtttat tgaaaggtat atatccgagg atttgtggga gaaacttttg tccacctacc
     1021 ggatggattc ctatgaaaac atatgggaag cattatttct atgccatcaa ttgttcaggg
     1081 cggtatccgg tgaggtggcg gaaaggcttc attatgccta tccggagtat gataggaata
     1141 taacaaaata taccagggac atgtataaaa aatacactgg taaaaccggc tgcctggata
     1201 gcacatatgc cgctgatata gaagagaggc gggaacagtg attacagaaa tgaaagcagg
     1261 gcacctgaaa gatatcgata aacccagcga accatttgag gtgataggta agattatacc
     1321 gaggtatgaa aacgagaatt ggacctttac agaattactc tatgaagcgc catatttaaa
     1381 aagctaccaa gacgaagagg atgaagagga tgaggaggca gattgccttg aatatattga
     1441 caatactgat aagataatat atctttacta ccaagacgat aaatgcgtcg gaaaagttaa
     1501 actgcgaaaa aattggaacc ggtacgctta tatagaagat atcgccgtat gtaaggattt
     1561 cagggggcaa ggcataggca gcgcgcttat caatatatct atagaatggg caaagcataa
     1621 aaacttgcat ggactaatgc ttgaaaccca ggacaataac cttatagctt gtaaattcta
     1681 tcataattgt ggtttcaaaa tcggctccgt cgatactatg ttatacgcca actttgaaaa
     1741 agctgttttc tggtatttaa ggttttagaa tgcaaggaac agtgaattgg agttcgtctt
     1801 gttataatta gcttcttggg gtatctttaa atactgtaga aaagaggaag gaaataataa
     1861 atggctaaaa tgagaatatc accggaattg aaaaaactga tcgaaaaata ccgctgcgta
     1921 aaagatacgg aaggaatgtc tcctgctaag gtatataagc tggtgggaga aaatgaaaac
     1981 ctatatttaa aaatgacgga cagccggtat aaagggacca cctatgatgt ggaacgggaa
     2041 aaggacatga tgctatggct ggaaggaaag ctgcctgttc caaaggtcct gcactttgaa
     2101 cggcatgatg gctggagcaa tctgctcatg agtgaggccg atggcgtcct ttgctcggaa
     2161 gagtatgaag atgaacaaag ccctgaaaag attatcgagc tgtatgcgga gtgcatcagg
     2221 ctctttcact ccatcgacat atcggattgt ccctatacga atagcttaga cagccgctta
     2281 gccgaattgg attacttact gaataacgat ctggccgatg tggattgcga aaactgggaa
     2341 gaagacactc catttaaaga tccgcgcgag ctgtatgatt ttttaaagac ggaaaagccc
     2401 gaagaggaac ttgtcttttc ccacggcgac ctgggagaca gcaacatctt tgtgaaagat
     2461 ggcaaagtaa gtggctttat tgatcttggg agaagcggca gggcggacaa gtggtatgac
     2521 attgccttct gcgtccggtc gatcagggag gatatcgggg aagaacagta tgtcgagcta
     2581 ttttttgact tactggggat caagcctgat tgggagaaaa taaaatatta tattttactg
     2641 gatgaattgt tttagtacct agatttagat gtctaaaaag ctttaactac aagcttttta
     2701 gacatctaat cttttctgaa gtacatccgc aactgtccat actctgatgt tttatatctt
     2761 ttctaaaagt tcgctagata gagttctata ttagagatgt aaagagtttt ggtgaagagg
     2821 tttgtgagta tggcttttat aaccagggtg caatgagaag cactaacagc agctagctta
     2881 agaacgcata ggatatactt tttatggaag tcacagagga ggaataaaat ttgaacagga
     2941 ttaacagagt aacctctatt cttattcagc tgcaatcaaa aaaataattc ctgccaaaga
     3001 aattgcacag cgatttaata taagcttaag gacagtttac agagatatcc ggacacttga
     3061 agaagccgga ataccaattg gatctgaggc cggaaaagga tattttcttg tagagggctt
     3121 cctacttctg ccggtaatgt ttacagcggc ggaagtgggt gcattgatta cagcagggaa
     3181 atttttaaat tgccatggag atgaatcatt tataaaggat tttgattcag ctatgtataa
     3241 aatcaaatct attttgaagc atggtgaaaa aaactatgca caggagttgg agaacagtat
     3301 taacgtgtac agcacatctg gacagaaaaa tacattggcg gataacgtta ttgcagcaat
     3361 tcagactgca atctgcaata aaagggtaat atcaattcaa tatcctgcat caggagggca
     3421 agaaccggaa agcagaatga tagagcctat atcactgggg ttttatgaac agaactggta
     3481 cttaatcggt tttgcaggct aagaaatgaa tataggaatt ttcgtgtgga tcggattaaa
     3541 agcatttgca tagaagaaga gctctgtcaa agccatgatg gctctttgga acaaatatta
     3601 aaacaaatgc tggttctgtt gcaaagtaaa aaaatatagc taaccactaa tttatcatgt
     3661 cagtgttcgt ttaacttgct agcatgatgc taatttcgtg gcatggcgaa aatccgtaga
     3721 tctgaagaga cctgcggttc tttttatata gagcgtaaat acactcaata ccttttaaag
     3781 tattctttgc tgtattgata ctttgatacc ttgtctttct tactttaata tgacggtgat
     3841 cttgctcaat gaggttattc agatatttcg atgtacaatg gcagtcaggt ttaagtttaa
     3901 aagctttaat tactttaacc attgctacct tcgttgaagg tgcctgatct gtaattacct
     3961 tttgaggttt accaaattgt ttaatgagac gtttgataaa cgcatatgct gaatgattat
     4021 ctcgttgctt acgcaaccaa atatctaatg tatgtccctc tgcatcaatg gcacgatata
     4081 aatagctcca ttttcctttt attttgatgt acgtctcatc aatacgccat ttgtaataag
     4141 cttttttatg ctttttcttc caaatttgat ataaaattgg ggcatattct tgaacccaac
     4201 ggtagaccgt tgaatgatga acgtttacac cacgttccct taatatttca gatatatcac
     4261 gataactcaa tgcatatctt agatagtagc caacagctac agtgataaca tccttgttaa
     4321 attgtttata tctgaaatag ttcatacaga agactccttt ttgttaaaat tatactataa
     4381 attcaacttt gcaacagaac ctcatttact atatgggcat ctctttcatt attaatacaa
     4441 agctttgtat ctccgatatt aggcaaaggt gtaaacgaat taggtgatac tataggattc
     4501 aacattatat taatcgtttc tttaataatg attatcttct tattttttat aaatcgtagt
     4561 aaaaatatct cctatgatta tataaaagtt caaagaggtg aagccaatga ataaattaga
     4621 aaaatggtct ttggtattta ttatttttac atttctctct tcattagcac ttttatattt
     4681 caaatataat tttagttcgg ttatgccagt cctaagtctt tctattttaa ctatactaat
     4741 attgttgacg agtattatta ctgtagtttc agttaatgat gaagatactt aaaacgttca
     4801 ttagtgaaac aggtattata ttaaaaaagc gtacgaattt gtacgctttt ttcttgtgtt
     4861 attattaaaa tctcataaca ggaaaatatt atgagatttt agacgctgtc agaacgtctc
     4921 ttttacatcg agtgacattg aatcaaagtc tttgtatgtt aatgatatat aaaattattt
     4981 agtagattca ttatagtaag ctagattagt tgctctactt gtttttattc tcttttgcct
     5041 ctaatttatt gagataacga taaatagttg tacgtgaaac ttgccactgc tctgcaattg
     5101 ttttaattgg cgtaccatta tcataaagtg tcttaagtaa gtttaaatct tgtttattta
     5161 atttttcagg tctacctcca tatcggcctc tagcacgtgc tgcaattcga ccggctgatg
     5221 atcgctctaa aattaaatta cgttcaaact ctgcaaatgc tgcgaataaa tgaaataata
     5281 attgtcctgt agaacttgat ttatccatcg ttatattttc ttctaaacta tgaaaactca
     5341 cacctcgttc gttaagttca ttaactaacg tgattaaatc ctccatgttc cgtcctagtc
     5401 tatctaatct ccaaacaaca atcgtatctc ctgacctcgc aaattcaatt gctttatcta
     5461 aaccaggtcg cttacttttt gaaccactca tatggtcatt aaatatcttt tcacaaccat
     5521 atgtatttaa tcgatcctcc tgtaaattca aattttgtaa tccagttgaa actcttgcat
     5581 aacctatttt caaaatacag acctcctata tacaccttta gtgtaccata acttgattac
     5641 gaggtctttt gtgaacatag attttttgtt gggtttttga acacataatt ctatgtaata
     5701 cttacttatt tagacaaaaa acaagagtgt acagaaaatg gttattttct ggacactctc
     5761 atctttaata atatatttta aatgtcatta acaaaactaa tttaataaga gtcaagtatg
     5821 gtttacatat gtattatgtt tgaaacatac ctctaattac tttttactaa tatcatttaa
     5881 aatgtctcgc aattcttcaa tttctttgtt atttaattct tcatttttcg caaaattcag
     5941 cactaaactt ttcatatccc ctccatacag tttattaaga aaggttttag cagttttcat
     6001 tttaatatcg tcttctttaa tatttgatga gtaaaaataa atattttctg atttgtatcg
     6061 ttttataatc tcttttttat atagtcttgt gattaatgtt ctaatcgttt tatcactaac
     6121 ttctttatat ttttgaattt caactacaat ttcattagct gatactgatt ttttatccca
     6181 tattatattc ataacatccc attcagccat agatatttca acttgcttat tggtcattta
     6241 aaacacccat tccttttaat attttttcac ttattaattc agcatttttc ccagacgggt
     6301 ttccatctga taaatgtgta gcaaaataat acttatcatg atttgtaatt acgtaaccta
     6361 caaaccaccc attattatac ttcccgttta ctatacctgt acctgttttc ccatacagtt
     6421 catacttttc atttttctta atcaataatg aagaagataa ttgattcttt gcttttttac
     6481 taaaatggtt attttgttcc atcatatttt taaaaactat tacttgttca agattagata
     6541 ttttcaaact atcttccatc caatagcttt tataacttcc caaattttca ttaccataat
     6601 ttaattgctt gagttgagcc gcagtatagt tctttggtat ttgattacta atacgttcga
     6661 agtaccaatt aactgaattt tgcattgctg tatttaaatc ttgttcctta ttccaagact
     6721 cgaaaagata atgtttatga ttccatgaca tacgtgaatt tttatcactt ataatatgac
     6781 ggtcaagtcc aaacagtgct aaataaattt tgtaagttga atcaggagaa tatctttttc
     6841 tactttcttt ttcattataa atatagtatt tgtctttctt catgctgtac ataacgaaag
     6901 atccactatt tgaaccaaaa tttttacttt catctaaaat ttggtaatcg ctttgtaagg
     6961 gctttttata attataatca gttaaggatt gccccattaa aaactggctt tgaattatca
     7021 tgataaaaaa agtaaaaata caaataaaaa ttagaattaa ttttgactgc tttttcagat
     7081 cggcttcttt tatattaatt aatctacttt tgagtaatga ttttttacca ttaaatgaat
     7141 ggcttaatat atttttgttg gaaaatgggg tttttaatac ggagtccata atagattccg
     7201 cataagtttt aaattcattt ttgttaatat tattaaggac aaatctatcg gcttctactt
     7261 cattgtcatg aattatcttt ctttttacaa tatgtactaa tggattgtaa ctcataataa
     7321 tagagaagat attaaagata attaaatgta aagtatctct atttttagca tgagcatatt
     7381 catgcagtat tatatatttt agtcttttat caattacact tttaaaatat gaactaggaa
     7441 tcaaaataat atatttccca taccaaaaag ttattggaga ttgaatagcc tctgcttttc
     7501 gaatcacaat atttttttta tattgatggt tgaaaagtat cgtatctatt ttattttttt
     7561 cattttcgtt tagataaagt gactgtttct ttaaatattt aagatataat aaggctttca
     7621 aaaatttaaa acttaaaata ataactaaaa ctatccaaat aactgtgcag atattatcaa
     7681 ttgaatccca attaaactta tggatatctg ttgtgaactc ttgaataggt ttggtggtat
     7741 ttatgttatg gttcaaatcg tgtgacttac tttcaactgt gggcgcttga ttattcacat
     7801 tattaaattt tataaaagag aatttaattg ggataaaagg aattaatcca gcaagcatag
     7861 ttagatacca aactttataa tttaaactat aattaaaata gcgttttaat atgtacctaa
     7921 aaaatactaa caatagaaat ataaaacaaa agcttactac gctcattatt agtaatttag
     7981 ccattttgac accttctttc aaatatttat aataaacaat tgacatcaat attacaattg
     8041 taatattatt gatttataaa aattacaact gtaatatcgg agggtttatt ttgaaaaagt
     8101 taatattttt aattgtaatt gctttagttt taagtgcatg taattcaaac agttcacatg
     8161 ccaaagagtt aaatgattta gaaaaaaaat ataatgctca tattggtgtt tatgctttaa
     8221 atactaaaag tggtaaggaa gtaaaattta attcagataa gagatttgcc tatgcttcga
     8281 cttcaaaagc gataaatagt gctattttgt tagaacaagt accttataat aagttaaata
     8341 aaaaagtaca tattaacaaa gatgatatag ttgcttattc tcctatttta gaaaaatatg
     8401 taggaaaaga tatcacttta aaagaactta ttgaggcttc aatgacatat agtgataata
     8461 cagcaaacaa taaaattata aaagaaatcg gtggaatcaa aaaagttaaa caacgtctaa
     8521 aagaactagg agataaagta acaaatccag ttagatatga gatagaatta aattactatt
     8581 caccaaagag caaaaaagat acttcaacgc ctgctgcttt cggcaagact ttaaataaac
     8641 ttatcgcaaa tggaaaatta agcaaaaaaa ataaaaattt cttacttgat ttaatgttta
     8701 ataataaaaa cggagacact ttaattaaag atggtgttcc aaaagactat aaggttgctg
     8761 ataaaagtgg tcaagcaata acatatgctt ctagaaatga tgttgctttt gtttatccta
     8821 agggccaatc tgaacctatt gttttagtca tttttacgaa taaagacaat aaaagtgata
     8881 agccaaatga taagttgata agtgaaaccg ccaagagtgt aatgaaggaa ttttaatatt
     8941 ctaaatgcat aataaatact gataacatct tatagtttgt attatatttt gtattatcgt
     9001 tgacatgtat aattttgata tcaaaaactg attttccctt tattattttc gagatttatt
     9061 ttcttaattc tctttaacaa actagaaata ttgtatatac aaaaaatcat aaataataga
     9121 tgaatagttt aattataggt gttcatcaat cgaaaaagca acgtatctta tttaaagtgc
     9181 gttgcttttt tctcatttat aaggttaaat aattctcata tatcaagcaa agtgacaata
     9241 gcattttaca agtatttttt attgttcgat tagggtaaac ctaaataata cataaattat
     9301 attacaatat gtttattata gaggctaaag tatcttagaa atttggatag taggtttttc
     9361 gggaataaaa gtatagttgg ctttaatata taattaagct aagctatcat ttatatttac
     9421 tcgattataa ttcgcacttc aactttttta taacgtaaaa attaaaacgt agttttattt
     9481 atctttagta atatcttttt aaacactaca gtttcttcat tagttaaatt agcgaagtaa
     9541 tgattattaa gttgataggc tttcttttct aatgttggcc ataagtcttt tgctttattt
     9601 gtactgttta ttagcacagt tcttctattt tcattatcag tttgacgtgt tattagatcc
     9661 tttttggaca tcttatctaa tattccagat attgttgaag gttctaaatt taaagtatta
     9721 ccaatcgctt taggtgtatt caaattacta ttaatcaagc aattcaaaac accatattct
     9781 gctggagtaa tattataggg acttaataaa cttttaaaat gtttaaaaac tctattctga
     9841 gaagtactca acaaataatt tatacaatta tctaattcca caactaaaac ctctcttaaa
     9901 tcattagtat tgactcgctt atcatatcat gataagtttt gtaggaaaat agttttgcaa
     9961 caaaaacata cttctacaaa acaattgtga aagaaggcta ataaatgttc aatgcggtag
    10021 tagtgagaaa aagtgcatca aatgttagtt ataaagtaga aaaagttgat gaatctcatt
    10081 tatcgaaggg tgatgtatta gtaaaagtgg tatactcttc aataaattat aaggatatgc
    10141 tagctttaca atataaaggc ggtgtaatta gagattatcc tatgattcct ggtatagatt
    10201 ttgcaggtat tgttgaatca agttcgaatg ataagtttaa agaaggcgat aatgtattag
    10261 ttactggtta tgatgttggc gtgacacata caggtggatt ttcagaatat gcacaagtgc
    10321 ctggagagtg gattgttcct attccccaag aaatgtctat taaagagtct atggtatatg
    10381 gcacagccgg ttttacggca gcattatcaa tttttgaact agaaaaatat ggaatgaata
    10441 tcaaatcaca acctgaaatt ttagtgtctg gggctacagg tggtgtgggc agtgttgcta
    10501 tacaaatttt acataaaatt ggatatgaaa atatcactgc tatcgtaaga aaagaaaagc
    10561 aaatagaaat cgcaaaaaaa ttaggtgcaa aacaagtaat aataattgaa gatgataata
    10621 aaccgcttaa aaaaggtatt tttgattatt tcttagatac agtggggagt aatgtaacat
    10681 tatacggttt aaaacgtcta aattatcaag gtgttgctac tgtatgtgga aatgtagcag
    10741 gaaattcact taacgctaat atattaccgt ttattcttag aggtattaaa ttaattggca
    10801 ttgattctgt atatgttgat cataatatcc gtgaagatat atggagtaag ttagcaaatg
    10861 aatggaatat aggaaattca cttctataca atgaaattgg atttgaagaa ttctataaaa
    10921 cgatagatca gcttttaaaa ggacaacatt taggaagaac tattttaaaa gtataagtgt
    10981 gagtattcat taatacattt actattaatt caatcatttt gcatttctct actaaccagt
    11041 gttataattt atataacgaa aatgattaac aattaatgca ccaatcccca cactattgca
    11101 gtagtgtggg gattttttcg atgctggctt ataaagtcgc ctattaatta tttgttgcgt
    11161 ttactaagcc aataagtata atacgcaaca gcacagccac tgatgactgg tgctatgatg
    11221 tgaacgaaaa tgattagcaa agtaatgcac ctcctctctt cgtcaattga cgcctgagag
    11281 ataggcgact ctattattat accatctgtg aatatacaag catatctact tccgataagt
    11341 cgtcttatgt tatataactt tgttttttat agtatcaaga caagaagaaa ctcgtttcaa
    11401 aaaccctcat gatttttaga gaaaaactct cttatttcat cgtctttaat aaaataatat
    11461 gccatctttc catctttata aaaatcaagt acctcatttt tatataaaag ccttaaatga
    11521 tgtgaagttg aagcaacact cattttcaat atcaaagaaa tatcacaaac acacaactca
    11581 tcttctttaa tcaaagataa tatgattttc aatttcttct catcacaaat tttttctaaa
    11641 atgttaagta atttcttaga tttatcatct tctaaaaaac ttaaagcatt gttaacttta
    11701 tcctcatgta cacagatcac atcacaagta ttttcataac tcatataaaa tcacacccta
    11761 aattaaaata taaatcctaa aattgtttga atagtgtcat tttcaataat aataaataaa
    11821 cctaaagcta tataaataat agccataatc caacgactaa atttctcaac aatttctcca
    11881 attcctggaa tattagctaa tttttgtgca gtaaacacca agaagaaaat taaaattaaa
    11941 aagacaaaca gagtaagtaa taaattagta acacttaatg tcacaaaata cggaacaaat
    12001 aaaccaatat tatcggcgcc acaacttgct atcgtaacaa ttgcaaccgt accaactaat
    12061 ttagacaatc ctttttcatt caattctttt ttagctctct tttctccttc acaatcatca
    12121 taaatagcca ctttaattcc aagataaatt ggtattaaac ccaataaacc taatatccac
    12181 ttttctggaa cataatttaa tacaaaagct aaaaacaaac taactaatat taaaataata
    12241 gaccctaaat attgaccaac ataaatatct ctatattctt ttctagtctt tgctctagca
    12301 aaaaatatta ataaaattac taataaatca actgctgtag caatataaag aacagcagca
    12361 gcaacaaccg tttgaatcat aatacacctc attcaaaaat atttttgaat gtattataac
    12421 ttatattttt aaataatcat aggtgcttta ttccaattgc tttattgacg ttgagcctcg
    12481 gaacccttaa caatcccaaa acttgtcgaa tggtcggctt aatagctcac gctatgccga
    12541 cattcgtctg caagtttagt taagggttct tctcaacatc aataaatttt ttcggcataa
    12601 atgcgtgtct atgcgtagac atggagacac ttcagaatta tggagtgatt acatgagttt
    12661 aactattttt ctttattcag ttttaggaag tttattagca aattatatct acgaaaaatc
    12721 ttcaaaataa ataacttttt cggttctact ttgtacactt tatctacctg gtagacctaa
    12781 ttgttattgc tttacaggtc taaaattcgt cgttataatc tagttaaatc ccgtaagggc
    12841 gcacttatac gtcggataaa tcgacatgtg caaaaacgta atcgaccttc gtcgattttt
    12901 ttatttcaaa attaaagaaa cggcttgaga tattccgagc agttataaaa attaatttgc
    12961 gttgaatatt gctactacat tcttgaaaaa gtgatgtaga tttatagccc ataacttttt
    13021 tgaattacat cgacgatacg gcgtcgaaag aaaaataaat agaccgtatg aaagaaaaag
    13081 ctacctcact ttatctgggg tagcttttat tttttatgcc cttattttga attttaagag
    13141 ggcattttaa agatttaggg gtgattcata tagttttata tctaaaactt atatatgctt
    13201 ttaaaacgca aatatgagcc aaataaatat atgctatttt caaaaacaaa aatttgagca
    13261 aaaacaataa ctatttttag acactgccca tttacatgca aattaaaaat tagcataaaa
    13321 ttctttaaaa cttccccacg tttttctaaa ttcctgtagg gcgtttttat caaaaatcaa
    13381 gacaagaaga aactcgttca cactcgtttc aaaaaaacaa gaaatctaat ctatacacct
    13441 accgttttcc aaccccctca aagcatacaa attaaaaaca aaattattca taatcttact
    13501 ttcttttaac aaaaacataa aaaccataaa tagacaaatt aactatcaaa ggcaataaac
    13561 agtataaaaa aaccacgaat aaatcttcat caacatctaa aataaaaaag aataaaacaa
    13621 ttaacaaaat actaattaac aaacctaaaa gtggcaaact ttttatatat ttttctaaat
    13681 tttcattcat aaaatagact cctttcaaaa atatgtttat aaatatatta aaataaatat
    13741 tgattttata aagcgcttac ttatacaatt aaaatatctt attatcttgg aggtatcaaa
    13801 tgaaaattat aaaattattt tcaataattt ccttgttcct actggtattt agcgcgaatt
    13861 tttctaatgc ttacgcaaat gaagaacaaa aaagttcttt actagaaaat caaaaagaaa
    13921 aattgaaaag caaaaacatc gaagtatcac aaatgaccaa gaaagaaata agttttctag
    13981 aacaattgca aaataaaaat gaagatatgc aaaaattcga aaagcaaatg aaaaaagaag
    14041 gatttaaaaa aataaagcta gaagacaaaa attctaaatt aaaatatcta gctacagaag
    14101 caaatgataa aaatgcatat ggctacatag ctaataacgc ttataaaaat gaaaaaacaa
    14161 aagaaattgt agtttctgaa acaatatatg ataactacaa caaaaaaatc acaaaattca
    14221 ttgccgaaaa aagaagtatg actgaaaaca aagagggaaa aatacttatt aacaaaaatt
    14281 acgttgaata taaggctgaa aaagttgata aaaacagacc ggtaacatat gcaggattca
    14341 aatggaacgg caaagcattc gcttgtagta tggctggact ttatgcatgt gctcactact
    14401 gtggagtatg ggcaatcgta aatccaatag ccggcggtgt atgtgaagca gtttgcggaa
    14461 ctgcatttgc agctggatgc tctgtaggtt gattttattc caattgtttt attgacgttg
    14521 agcctcggaa cccttaacaa tcccaaaact tgtcgaatgg tcggcttaat agctcacgct
    14581 atgccgacat tcgtctgcaa gtttagttaa gggttcttct caacatcaat aaattttttc
    14641 ggcataaata cgatgttcct tatttatcct cataaaaaac aatagctgaa atatataacc
    14701 aattactgtg tgtttgaatt tctaatacat gaatatcatt ctttaaaaac ctattaactt
    14761 gtttatctaa ttgacgatga gtaaaagtag cgaaagtttt aatcttcatg atatctctcc
    14821 ttttataaaa atagcaatcc ttattacaat attaaacact tttattttgg attttaagag
    14881 gcattttgaa gacttagagg caaatcatat aggttttgta cttaaaaatc tatacagtct
    14941 cttaaaacgc aaatatgagc caaataaata tatgctaatt tcacaaacaa aaatttcagc
    15001 aaaatcagtg actaattttt tagatactgc ccatttacat gcaaatttaa aaattagcat
    15061 aaaatacttt aaaacttccc catgtttttc taaattcctg cagggctttt cttatcaaaa
    15121 acttagaaat tttaatttaa ctctaaaatc tccgtaagag cataagggaa atttgctatc
    15181 attcaaaaat gatagatctg gcaaggccag acattccaag ggttttaagt tattttaaag
    15241 tgatatcata caaagctgta gtgtcacact tttgtgacac tacatacagc atttgtcaca
    15301 aaaataagac agcacttttt tacagaaaaa caataaaaaa agacatcagt tatcactaat
    15361 gtcttaaata ataattttgc ttttcgaaat tccaaattgc ggtaattgaa tgtgcttttt
    15421 ttcttcgtct gtcgttttat cttcatcact tgtattaatc aaattaccat cttcggcatc
    15481 gtctaagttt aaaattttat gcttttgttt aagcaatcca ccataactta acatacgttt
    15541 tcgatacaaa cctttttcta aatcacttac aatttcttga tttttttcgt cgtcatcagt
    15601 taaaaagtca gatgatttaa cggaatattt tgatgtctct tcgagtgtta taaaatcatt
    15661 tgaattattg attaaagata ttatattgtt tcatgttttt acggcgcata taaagggcat
    15721 gtgtttcttc aagttcagtt agaattgttt gcattaaata agcttgcatt gacttgattg
    15781 tttccttttg gcctttaact cccctatcat gtatagcttt tttaagtctt tttaaagaag
    15841 ttaatatttc atcctcaatg tcctctaaca tgtaatgcat atcttcatgc cttgaattaa
    15901 atgatttttt tgctttaaga ataacagcct ttatgatttc taaatctcta taatcatatt
    15961 ttaataaata attagttagt tgttctggga attcttgcaa tagcatttct ttatcatcaa
    16021 aattatgtgt aaattgattt gaatgatttg aatgattact aatttcattt ttgtacttta
    16081 tatcattcaa gtcattcata tcattattct cagtatcatt aaagtcaatg tcattaaagt
    16141 cagtatcatt agtgttcgat tttcgaactt ctggacgttc gaaaatcgaa cttctggacg
    16201 ttcgattttc gaacttctgg acgttcgatt ttcgaacttc cttctcgccg taaggttcaa
    16261 catcgttttc ttctttttct attttgtaaa tatcacgttc tgtgacaata ggtttcatta
    16321 aatatagaat atttggttta tttaaaccac gtcgtttttg aatgagtaga ccatcgtttt
    16381 ctaacccttt ttttattttt gttaactttt cttttttaca atttaagatt tccattagct
    16441 tttcatttga ataaacaaag taaatgttac catcttcatc aacccagcta tttttaatag
    16501 ataaatttaa gcgatcacgt aagatagcat aggctatttt catatcatta gttagatttt
    16561 tataattttc actggtaaag aatactttag ggatttgata aaatctttct ttgtaatttt
    16621 cttgcactgt aaaatattga ttttgcatga caaaaaacct ctttccatat tttagtttgg
    16681 taagaggtaa taaaacgttt ttatttagct ttacatttat ttaatgattt aggtgcttgc
    16741 actaagatat tattcattat ataatacaag tatcgaaaat tatataaata aacagtttct
    16801 aaacgtttta ttaccaaacc ccgactatta ccagtagttg gggtttttgt tatattaagt
    16861 ttattatagc actttaaata aacttataaa agggaaaata tagctttatc aagggtttat
    16921 aaacccttga taaatatcat aaacctttca taaacccttg ataaaaaggt tgatggatgt
    16981 ttatttttat ttattaatca ctttattatt aagcattata agcttataat attttatcaa
    17041 gggtttataa acattttata aagggttgat gatatgaaaa gtgtgaaaaa gttgagtgaa
    17101 gaattagggg ttagtaagca aacgattttt aataatatta agcgattgaa tatagagaca
    17161 ataaaacagg aaaacacttc gtttattaaa gaagataccg atatagaaaa aatcattcaa
    17221 agagtaaatg aaaataaaaa gaaatatggt tttgaaagta ctactgaaga caaacaaaaa
    17281 aaagggtcgg ataatattaa ttttgaatcg aaaagcgatg ctcaaatagt agaaatcctt
    17341 aaaaatcaga ttgatacttt aaataatcaa attgaaaaac aagaaagtcg tcatgaaaca
    17401 acaattgaat tttacagaaa agagttgcaa gaaagatcaa aattgcttga aaatcagcaa
    17461 gttctggcat tagagagtaa taaaaagatt caaaaattag aaaatcaatt agaaaaagaa
    17521 aaacacctta attatccctt tgatacatct actaacacta gacaaaacgt tgatgcacaa
    17581 gaaaaaacat atactactaa tcctgtaaat attaacagag atcaggaaga aactaaagaa
    17641 acagagattc aatataagga tatatctgga agtcaaagcg acgaaagtac acaaggtgaa
    17701 gaagcaaaaa aagaagacgt tccagctaat ctaaatgaca atgatagtga tatagaagaa
    17761 aagagtgaag aaacggaacc taaaaagggg ttttggagtc gtttgtttgg tagctaaaat
    17821 aattgattag gcactaaaag ttataaaatt ttagtgtctt ttatatagtg agaacttctg
    17881 gtaatcatcg attatgtaaa ctaaagtatt tcaaataatt aactgtatta atactctcat
    17941 catgattgcg ttataaacgt tcgttattga gacaaaattt aatagtacta ctacacaaaa
    18001 agagagtgcg aattcgcact ctctttttgt gataaatgaa tggttaagaa aataattcat
    18061 ccacagttgt atcaaacaat cttgccaact taaatgctaa tgtcaatgta ggatcatatt
    18121 tattgttttc tattgcatta atagtttgcc tagacacttt taattcttta cttaaagttt
    18181 cttgagaaat tcctttttgt tttctatatt ctctaattct atttttcatt aatttaacct
    18241 ttagatgtat attttttatt tgtagtatag taattaaaca gcataagaaa tagtgctaca
    18301 attataaaga aaatttctgg atattgagaa aaccaagatc cttcaatact tggtgacaaa
    18361 cctgtaaatt taagcactag tgtaaataac atacaatata caatccaaat aaaactttta
    18421 gccagtattt caataaacat tttacgttgt ctttcatcgt atcgatcttg ttgtcctttt
    18481 ttatctaatg tttctgaagg taaatatttg ttagttatag ccgtccataa acaagaaaaa
    18541 attaaaataa taataaaagg aattaaattc attataacac ctcataaatg taaaaagtat
    18601 ttgacattta tgagtgtaaa tatttttgat acaaatgtca aatacttttt acattataat
    18661 atattttaaa acaccttatt agtaaaacaa ttactatata gaaagctgcg aactcgtact
    18721 cttttttctt gtataattat taaaatctca attcaataat atgttatgga atttgagaca
    18781 ctgtgagaga cgctcatttg cattgacaat caatttatca agataatccc ttatcatgtt
    18841 taattctata aactgtttgt cttgtgatat taacttcttt cgcaatctta ctaatcgctt
    18901 tgccttcttc taacatttcc accacgcgat gataaataac acgtttctgt gggtctttag
    18961 catttggtga ataaagtaaa gggcgccctt tatatacgcc tttttccttc gcaacttgaa
    19021 tcccttgcgc ttgtcgacgt ttactttcat ttctctcttg ttctgaaacc attgctaata
    19081 tttgaatgat taaatctttc ataaacttat ccagtaatgg attgccaatt acttcattca
    19141 tcataggtaa gctggtaatc attaactgaa cgtctttttc ttttaaataa ttcacagttt
    19201 caataatttc atcatagtta cgtcctaaac gatcaataga ttccacaacg aatcgatctc
    19261 ccattctgac aaaattgagt gcttcttgaa atacaggtct attttccact gactttcccg
    19321 actgtttctc tgtaaagatt ttctccacac caaacgtctt taaattatcc aattgtcttt
    19381 ctaaattttg atctatcgat gatactctcg cataacctat aatcattcat cttcactcca
    19441 taataaatat acaccctaat catacgtttt aattgttata atttcaacaa ttctttttgt
    19501 atggttaggg tgtactcaaa gtgtacatat ctataattaa aacttactaa aaataaatat
    19561 agattttttc tttgtaacag aaccgttcat ttgaaggtca tctctatcat aaatatttaa
    19621 attaactaaa aattttaatc atctgtttaa tacttatgaa atgtatttac ggtaggtatt
    19681 aaaattgatg aaatttatat aagtgctttc aatgaaaatg accgtttatt tatcctcctg
    19741 atttaaggag ttagaaattt cgaaaacgat tctttccatt tgttgcattt gttccatgtc
    19801 cagatattta atacattata gaaaaccaaa gaccatcact aattaaacgc agttttaaaa
    19861 tttcatcagg attgccttcg tctttaaaat gggcctcttt taatataagt tctactcttt
    19921 catacctaac tctttcaatg ccatcgtttc atacgccgat tctcctgatt ccatagcaaa
    19981 ctcagcgata aacattggga atactgcatt gagttctatt atatgctctt tcattcgtgg
    20041 ccatatttca cctccagctt taccgtatgc tgttataagt tgctctaatc cttcgtcgtc
    20101 gaatacacga tggtgtccta taaagtccat tgatgggtcg gagtgggttg cttcagtcca
    20161 gtctatgaga cctgtgacgt ttgcttggtt atctaccatt atatgtcctg gatgtaagtc
    20221 cccatgtatc atggtcgcat gtcgaggcca tagttcgtcg ttttctaacc attgtttcca
    20281 tctgttccat aattcatctg atacgccata agtttcttta actttattca ttcttctttg
    20341 aaagtcattt tttatttctt gtatggtttt gatatttata tgctgaacgt taatgttttc
    20401 ttctggtatg ttgtgtaaat ctacgagtgt ttcagctaat gtgttaataa agttttctgg
    20461 taatggtttg tgttcaattt cccatacata attttgtatt tctggatcta ttgtggctgc
    20521 gggtttacct gtaagttttg ggtaagcaat aaggtctttt gcatgtactt tccacttcgg
    20581 tatttcaaat gaaacattct tctgtaagaa gtctaccgtt tgtttttcgg gttttgttcg
    20641 tttataaacg tcaggtcttc ttggtagtct caaaacccat tctactccat gtttatcttt
    20701 tccaaatgca acttgaaaat caagtcccga ttcattcaat gagattgttt gaggttggat
    20761 gtgtaattga tatttttctg cacatttaat aatttcatta tgtcgagtca ttttattgga
    20821 tccttatttc tattatattt ttcttgtgaa cgtatttttt atattgatat aaatgaacct
    20881 aatattcaat ataaattagt gtatagtttt taagttatat catgaagaga ttgtcctgtt
    20941 aattcccatt ttttatctga tacatgttta acaaaccttg tatcatgtga tgtaaacaaa
    21001 atgattccag gatatttatt cataaacatt tctaatgctt ctaatgtttt aatatctaaa
    21061 aaattagttg gttcatccaa aattaacata ttcgctttcg ttgaaaataa tactgctaac
    21121 gataatttcg ttctttcccc accactcaaa acattacaag aacgatcaag tgcttcattt
    21181 aaacccaagt tatttaaaat agctctactg aatgattctg atgaatccgt ttcatccatt
    21241 aaatattgca ataatgaaac gtcacgcatg tcttcataag caagttgacg atagtatgcc
    21301 atttgcactt taggagaaca atcaattccc tctatttggt ggtaaatagc ttcaagtaaa
    21361 gttgtcttac ctacaccatt tgcacctacg agcgctatat ttttgccata tggtatttgg
    21421 aatcgtactt gtgttagcag tttttgactt cctttaacca atgttagatt ttgtgcaatg
    21481 attggataat tattatggat atcataaatt ttattttgtg ggaaattgaa ttcatgataa
    21541 ctttgtggtt tttcaacttc ttccaaatgt tccattcttt tttcaatatg cttagcttgt
    21601 ttttgagcag ccttctcaac cgtgcctttt tgttttgatg cacttaaacg atctggtgct
    21661 atacttttgt ttttttgttt tgatgatgct tgtgccattt gttgcgcttg atttcgttta
    21721 gctttactgg cttgggacaa tctttgtttt tcacttatat actgttcata ttgacgttgt
    21781 tgttctaact gttcttgttc atattgattt tgatactgtg tgtaattacc tttaaacact
    21841 cttattgtgc catcttcttg tatatcccaa attgtgtcag caatttggtc tataagtgct
    21901 ctatcatgac ttactataat taaagtacca tagtaatatt ttaaaatatt tttcagataa
    21961 tctttaccaa ttttatccaa gtgatttgta ggttcatcta aaagtaatat cggactataa
    22021 tttgatatga cattagctaa tttatatttt gctttttcac caccactcat actgtcggtt
    22081 gtatgcatag gtatatggag ttcactcatt aaactaccgt ctaacgtgtt aaaatcattt
    22141 tccacatcca tgttaagctg ttcaaaatat tgaatttcgc caaccgtttc aactgttcca
    22201 gattctggtt ttgttttttg agcaatcata tttagtaatg tggttttgcc agtaccatta
    22261 cccccaataa gtgctatttt ttcaaattgg taagcgtaaa gatgaccgat gttaagtgat
    22321 cgtaaatctg tcaatttatg attgatttgg ttaaatttaa ttgtatattg ttccatattt
    22381 atacactcct tgtatattta aaggacgtgt acgcaaaaaa atgagacagg ctactcccgt
    22441 ctcattcaca ttacactttc aaacacttaa aaatttatta tgatgtttta gtatttgaaa
    22501 gcgtttatta ttcctatcga aggataaaaa atgacataag tcatcctatg agtgtgtatt
    22561 gcggacaagc ctttttgaat taatttagtt ttgtattcaa aaaggtttat ttgagtctca
    22621 tagaagctgt cattttaatc ctccttcatc gataaaatag taatgttaat ataacatttt
    22681 gttggttttt ttacaatata tctctaagta gaaagattat ataacaaaag tataaaaata
    22741 caattttaga ttgattatac atctccttaa tttagagtgt actcataaaa tacggttctg
    22801 ttgcaaagtt gaatttataa tataatttta acaaaaagga gtcttctgta tgaactattt
    22861 cagatataaa caatttaaca aggatgttat cactgtagcc gttggctact atctaagata
    22921 tgcattgagc tatcgtgata tatctgaaat attaagagaa cgtggtgtaa acgttcatca
    22981 ttcaacgatc taccgttggg ttcaagaata tgccccaatt ttatatcaaa tttggaagaa
    23041 aaagcataaa aaagcttatt acaaatggcg tattgatgag acgtatatca aaataaaagg
    23101 aaaatggagc tatttatatc gtgccattga tacagaggga catacattag atatttggtt
    23161 gcgtaagcaa cgagataatc attcagcata tgcgtttatc aaacgtctca ttaaacaatt
    23221 tggtaagcct caaaaggtag ttacagatca ggcaccttca acgaaggcag caatggctaa
    23281 aataattaaa gcttttaaac ttaaacctga ctgtcattgt acatcgaaat atctgaataa
    23341 cctcattgag caagatcacc gtcatattaa agtaagaaag acaagatatc aaagtatcaa
    23401 tacggcaaag aatactttaa aaggtattga atgtatttac gctctatata aaaagaaccg
    23461 taggtctctt cagatctacg gattttcccc atgccacgaa attagcatca tgctagcaag
    23521 ttaaacgaac actgacatga tatattagtg attagctata ttttttactt tgcaacagaa
    23581 ccagccattt aatatgactg ttacaattac taagattcaa gcactattac gccgcacgta
    23641 tgatttcacc actcaagtta ataatttaac agtagatgat tgcgagttac tacttgatgc
    23701 agcaaagctt aaatttaatg aagaaaccat agacctgaca cacactgaat tgcaaatcat
    23761 gcatagctta ttccagaaca agggcaaatt cgtcagtcgt aatgcgttaa tcgaaaaatg
    23821 ctgggaatca gaacacttca ttgatgacaa tacgcttgct gtcaacatta cacgtttacg
    23881 caaaaagcta caaaaactag gacttacaga ttttatcgaa acgaagaaaa atgtcggata
    23941 tcgtgtaggt gacgtatgaa tttcttgaaa tcaatccaac gtgaaattta tattgtcatc
    24001 cttacttgtg ctttattcta ctttatatta ttcatgtata atgtgccgat gcaagcatat
    24061 atgattggtc taggtattgt attgtttgtt tcaatgattt actggggtat ccattacatg
    24121 aactttaaaa aagaataaac actacaggaa cagaacgaag atttaagaat cgaaaaccat
    24181 aaacttcgta atgactttat taactaccaa agtgagttag agtcatattt tttaatgtgg
    24241 gtgcatcaaa tcaagacacc gattacagca tcaaagttac tgcttgaaga tcctgatgaa
    24301 cacgtgattt ctaacgtgcg taatgaagtc ttacaaattg ataattacac gaatcttgca
    24361 ctgaactatt tgaaactcat gaaccaaaag acatacatgg tctttatgga agtgagtgta
    24421 gatgaattaa ttcgaccact gattaaacgt tatgcgatac agtttattca tcatcaaaca
    24481 aagttgcatt atgagaaaag tgaagcggtt atattaacag atgccaaatg ggcatcaatt
    24541 atgattgagc aaatattaaa caatgcatta aaatatgcac gtggcaaaga tgtgtggatt
    24601 acgtttgacg aaaatacaaa gaaattatca atccgagata acggtatcgg cattaatgcg
    24661 agtgatttac cgaaaatctt tgataaaggt ttctcgggct ataacggtag aataagtgag
    24721 aaatcaagcg gtattggttt atatattgtc agcacaatct caaagcgctt aggccataaa
    24781 gtaagtgcta catctacatt aaacgatggt tcaatattca ccattcaatt taaataactc
    24841 caatctttca tttttgtaag attagcggct gtttttgtaa gaatagataa aggcagcctt
    24901 ttctaatcgc gcgtaagata aaggtaacaa caaactaaga aaggtgccag aggtgaaaaa
    24961 tttgaataat ataattgaaa taaataactt aacaaagcaa tatggaagtc agatagcagt
    25021 taataatttg agtataactg ttgaaagtgg acaaatttat ggttttttag gaagaaatgg
    25081 tgcaggcaaa acaactacta taagaatgct tttaggctta attaaaccta cgaaaggtaa
    25141 tattaaaata tttgaaaaag agttcgaaag taataaaact gaaattttaa aaaatattgg
    25201 tgctatggtt gaaacgccag gtttttatag taatttgaca gctaaagaga acttaactat
    25261 aaatgctaaa atattaggta tacaaaaaga aaatgcaatt gaagaagtgt tagaaatagt
    25321 aggactagct tctgaaaaag taaaattgtt taaaaattat tctttaggta tgaagcaacg
    25381 tttagggatt gcgagagctt tattgcacaa tcccgaatta ttgatacttg atgagccgac
    25441 gaatggatta gatcctattg gcataaaaga aattagaaag ttgattaagg atctggctca
    25501 atctagaaat ataaccattt taatttcaag tcatatattg tcagaaatag agcagttagt
    25561 agacaaggtg ggtattattc ataacggagt tttgttagaa gaaattatgt atgaagattt
    25621 aaaaaaaaag aacagacaat ttataagtat atcagtatca gatgaagaaa aagttgcatg
    25681 tttgttggaa actaacttcg gaatttatga ctataaaatt aaagaaaatg gcgaatttaa
    25741 aatttattca catattgata gacaacaaga aattaataga ttattagtat taaacaatat
    25801 tgatgttttc cagatgagag tgatagaaga taatctagaa acttatttcg aagacttagt
    25861 aggaggtggc acaattggat aatctactcc gtacagaatt tattaagtta aaaagatcat
    25921 atatgtttct aataagtatt ttaggtacat gcgtagcacc ttttatggtg gttgtagctt
    25981 cttttattag tatgcggacg aaagtaccga ctcctaatat tgtatttaaa cagttatttg
    26041 aagaagtcag tttatatcat atgctaatta ttggacctcc tctatatggg gttataatag
    26101 cctatttgtt tggaagagaa tatatagaag atactttaaa aaacttatta attataccta
    26161 tatctagaga aagtttttta gtaagtaaaa taatattatt attcttgtgg attcaaacac
    26221 tatctgttat tgcatggttg ctaactttaa tgctaggtat gctattgcat tttcaagggt
    26281 taagccagag tttaataatt gattcattct ttacatttgt tattggcgga gtgttattat
    26341 ggatattatc tccaccaata attattttgt cgatatattt taaaaattat gttcccacaa
    26401 ttgttttaac cataataatt actttgataa atttaatgac tgctaattct gaacatagag
    26461 gattatttcc ttgggctgca gttggagaca tatctagagg aacattacct aatacttatc
    26521 catttctatt atctttaatt atcataattg ttacatctat attcagtgta attatattat
    26581 tctcatactt taaaaaaact gatataagtt aaaaggagga gaaaaatggg ttttatagag
    26641 cagattaaag catttatttt aggtgtagtt gaagggttga cagaatttgc tccagtatca
    26701 tcaacaggtc atatgattat tgttgatgat atgtggttaa acactgctga cgatttagga
    26761 agtgcgtctg caactacttt taaggtggta atacagttag gaggttctgt tgcaaagttg
    26821 aatttataat ataattttaa caaaaaggag tcttctgtat gaactatttc agatataaac
    26881 aatttaacaa ggatgttatc actgtagccg ttggctacta tctaagatat gcattgagct
    26941 atcgtgatat atctgaaata ttaagagaac gtggtgtaaa cgttcatcat tcaacgatct
    27001 accgttgggt tcaagaatat gccccaattt tatatcaaat ttggaagaaa aagcataaaa
    27061 aagcttat
//
