LOCUS       NZ_CP013227            22042 bp    DNA     circular CON 08-MAY-2024
DEFINITION  Staphylococcus aureus strain UTSW MRSA 55 plasmid UTSW55_1, complete
            sequence.
ACCESSION   NZ_CP013227
VERSION     NZ_CP013227.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN04254471
            Assembly: GCF_001580515.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 22042)
  AUTHORS   Copley,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-NOV-2015) Orthopaedics, Childrens Medical Center, 1935
            Medical District Drive, Dallas, TX ST7.03, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SMRT Analysis HGAP v. 2.0.1
            Assembly Name                     :: UTSW55
            Long Assembly Name                :: Staphylococcus aureus UTSW55
            Genome Coverage                   :: 955
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001580515.1-RS_2024_05_07
            Annotation Date                   :: 05/07/2024 02:58:19
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,080
            CDSs (total)                      :: 2,998
            Genes (coding)                    :: 2,833
            CDSs (with protein)               :: 2,833
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 165
            CDSs (without protein)            :: 165
            Pseudo Genes (ambiguous residues) :: 0 of 165
            Pseudo Genes (frameshifted)       :: 118 of 165
            Pseudo Genes (incomplete)         :: 60 of 165
            Pseudo Genes (internal stop)      :: 33 of 165
            Pseudo Genes (multiple problems)  :: 40 of 165
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP013227.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..22042
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="UTSW MRSA 55"
                     /isolation_source="USA: Dallas Texas"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="UTSW55_1"
                     /geo_loc_name="USA: Children Hospital, Dallas, Texas"
                     /lat_lon="32.775833 N 96.79666700 W"
                     /collection_date="2013-11-05"
                     /collected_by="Lawson Copley"
     gene            join(21453..22042,1..>1)
                     /locus_tag="AS858_RS00005"
                     /old_locus_tag="AS858_14820"
                     /pseudo=""
     CDS             join(21453..22042,1..>1)
                     /locus_tag="AS858_RS00005"
                     /old_locus_tag="AS858_14820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001652331.1"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /name="rhomboid family intramembrane serine protease"
     gene            <2..314
                     /locus_tag="AS858_RS15605"
                     /pseudo=""
     CDS             <2..314
                     /locus_tag="AS858_RS15605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006190421.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="iron transporter"
                     /name="iron transporter"
     gene            620..1569
                     /locus_tag="AS858_RS00010"
                     /old_locus_tag="AS858_14825"
                     /pseudo=""
     CDS             620..1569
                     /locus_tag="AS858_RS00010"
                     /old_locus_tag="AS858_14825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500184.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /name="PhoH family protein"
     gene            1570..2037
                     /gene="ybeY"
                     /locus_tag="AS858_RS00015"
                     /old_locus_tag="AS858_14830"
     CDS             1570..2037
                     /gene="ybeY"
                     /locus_tag="AS858_RS00015"
                     /old_locus_tag="AS858_14830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500183.1"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]; GO:0004540 - RNA nuclease activity [Evidence IEA]"
                     /GO_process="GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="WP_000494134.1"
                     /translation="MFTIDFSDHTGLVKDAWYKQIEDLLEFAKKEEHIEDDAELSVTFV
                     DKQEIQEINRTYRDKDKVTDVISFALEEDEPEIDFSGLDIPRVLGDIIICTDVAQEQAN
                     NYGHSFERELGFLALHGFLHLLGYDHMTEADEKEMFGRQDTILNAYGLTRD"
                     /name="ybeY"
     gene            2040..2384
                     /locus_tag="AS858_RS00020"
                     /old_locus_tag="AS858_14835"
     CDS             2040..2384
                     /locus_tag="AS858_RS00020"
                     /old_locus_tag="AS858_14835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="WP_000819532.1"
                     /translation="MKRFKYALDGLKILIQKDYKFLLHVFAMIVAIVFGLVLNINRIEW
                     IFILIAIALVLTVEALNTAIEYVVDLVTVEYHDLAKYAKDIAAFSVLIVSILAFIIGLI
                     VFLPHFIALF"
                     /name="diacylglycerol kinase"
     gene            2395..2803
                     /gene="cdd"
                     /locus_tag="AS858_RS00025"
                     /old_locus_tag="AS858_14840"
                     /pseudo=""
     CDS             2395..2803
                     /gene="cdd"
                     /locus_tag="AS858_RS00025"
                     /old_locus_tag="AS858_14840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002455278.1"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004126 - cytidine deaminase activity
                     [Evidence IEA]"
                     /GO_process="GO:0008655 - pyrimidine-containing compound
                     salvage [Evidence IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /name="cdd"
     gene            2804..3704
                     /gene="era"
                     /locus_tag="AS858_RS00030"
                     /old_locus_tag="AS858_14845"
                     /pseudo=""
     CDS             2804..3704
                     /gene="era"
                     /locus_tag="AS858_RS00030"
                     /old_locus_tag="AS858_14845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134760.1"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA];
                     GO:0003723 - RNA binding [Evidence IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /name="era"
     gene            3732..4480
                     /gene="recO"
                     /locus_tag="AS858_RS00035"
                     /old_locus_tag="AS858_14850"
                     /pseudo=""
     CDS             3732..4480
                     /gene="recO"
                     /locus_tag="AS858_RS00035"
                     /old_locus_tag="AS858_14850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500178.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA];
                     GO:0006281 - DNA repair [Evidence IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /name="recO"
     gene            complement(4630..6021)
                     /locus_tag="AS858_RS00040"
                     /old_locus_tag="AS858_14855"
     CDS             complement(4630..6021)
                     /locus_tag="AS858_RS00040"
                     /old_locus_tag="AS858_14855"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500177.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0004820 - glycine-tRNA ligase activity [Evidence IEA];
                     GO:0000166 - nucleotide binding [Evidence IEA]"
                     /GO_process="GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase"
                     /protein_id="WP_001030080.1"
                     /translation="MAKDMDTIVSLAKHRGFVFPGSDIYGGLSNTWDYGPLGVELKNNV
                     KKAWWQKFITQSPFNVGIDAAILMNPKVWEASGHLNNFNDPMIDNKDSKIRYRADKLIE
                     DYMQDVKGDENFIADGLSFEQMKKIIDDEGIVCPVSKTANWTEIRQFNLMFKTFQGVTE
                     DSTNEIFLRPETAQGIFVNYKNVQRSMRKKLPFGIGQIGKSFRNEITPGNFIFRTREFE
                     QMELEFFCKPGEEIEWQNYWKTFASDWLTSLNMSSENMRLRDHDEDELSHYSNATTDIE
                     YKFPFGWGELWGIASRTDFDLRKHAEHSGEDFRYHDPETNEKYIPYCIEPSLGADRVTL
                     AFLCDAYDEEGVEGSKDARTVLHFHPALAPYKAAILPLSKKLSGEAIKIFEQLSSKFSI
                     DFDESQSIGKRYRRQDEIGTPYCVTFDFDSLEDNQVTVRDRDSMEQVRMPISELEAFLT
                     EKTKF"
                     /name="glycine--tRNA ligase"
     gene            6356..6979
                     /locus_tag="AS858_RS00045"
                     /old_locus_tag="AS858_14860"
     CDS             6356..6979
                     /locus_tag="AS858_RS00045"
                     /old_locus_tag="AS858_14860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001797828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_001789866.1"
                     /translation="MELSQRQERIIEIVKTKGPITGEQIADKLNLTRATLRPDLAILTM
                     SGFLEARPRVGYYYSGKSKGKFFNEKLRQFEVKDYMSQPVVLRENTTVYDAICTIFLED
                     VSTLFIINEDNDFVGVCSRKDLLRASMIGADIHKVPISVNMTRMPNVTYLEESELVIYA
                     ADRMIEKEIDSIPIVRKKDNQKYEVIGRISKTTIAKLLVALYKE"
                     /name="helix-turn-helix transcriptional regulator"
     gene            6990..7806
                     /locus_tag="AS858_RS00050"
                     /old_locus_tag="AS858_14865"
                     /pseudo=""
     CDS             6990..7806
                     /locus_tag="AS858_RS00050"
                     /old_locus_tag="AS858_14865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500175.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016776 - phosphotransferase activity, phosphate group
                     as acceptor [Evidence IEA]; GO:0004674 - protein
                     serine/threonine kinase activity [Evidence IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]; GO:0006468 - protein phosphorylation
                     [Evidence IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, water dikinase regulatory protein"
                     /name="pyruvate, water dikinase regulatory protein"
     gene            7867..9644
                     /gene="dnaG"
                     /locus_tag="AS858_RS00055"
                     /old_locus_tag="AS858_14870"
                     /pseudo=""
     CDS             7867..9644
                     /gene="dnaG"
                     /locus_tag="AS858_RS00055"
                     /old_locus_tag="AS858_14870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500174.1"
                     /GO_function="GO:0003896 - DNA primase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006269 - DNA replication, synthesis of RNA
                     primer [Evidence IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /name="dnaG"
     gene            9879..10913
                     /locus_tag="AS858_RS00060"
                     /old_locus_tag="AS858_14875"
                     /pseudo=""
     CDS             9879..10913
                     /locus_tag="AS858_RS00060"
                     /old_locus_tag="AS858_14875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011275651.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]; GO:0016987 - sigma factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]; GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /name="sigma-70 family RNA polymerase sigma factor"
     gene            11136..11587
                     /locus_tag="AS858_RS00065"
                     /old_locus_tag="AS858_14880"
                     /pseudo=""
     CDS             11136..11587
                     /locus_tag="AS858_RS00065"
                     /old_locus_tag="AS858_14880"
                     /inference="COORDINATES: protein motif:HMM:NF024255.4"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine(22)-N(1))-methyltransferase TrmK"
                     /name="tRNA (adenine(22)-N(1))-methyltransferase TrmK"
     gene            11708..12803
                     /locus_tag="AS858_RS00070"
                     /old_locus_tag="AS858_14885"
                     /pseudo=""
     CDS             11708..12803
                     /locus_tag="AS858_RS00070"
                     /old_locus_tag="AS858_14885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500171.1"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0051540 - metal cluster binding [Evidence
                     IEA]"
                     /GO_process="GO:0008150 - biological_process [Evidence
                     IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /name="Nif3-like dinuclear metal center hexameric protein"
     gene            12917..14261
                     /locus_tag="AS858_RS17300"
                     /old_locus_tag="AS858_14890"
                     /pseudo=""
     CDS             12917..14261
                     /locus_tag="AS858_RS17300"
                     /old_locus_tag="AS858_14890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500170.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016887 - ATP hydrolysis activity [Evidence IEA];
                     GO:0004386 - helicase activity [Evidence IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /name="DEAD/DEAH box helicase"
     gene            14271..15161
                     /locus_tag="AS858_RS00080"
                     /old_locus_tag="AS858_14895"
     CDS             14271..15161
                     /locus_tag="AS858_RS00080"
                     /old_locus_tag="AS858_14895"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500169.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="WP_000924214.1"
                     /translation="MLLGSHVSMSGKKMLEGSAIEAHEYGETTFMIYTGAPQNTRRKSI
                     EDLNITKGHEVMEKYGLSNIVVHAPYIINIANTTKPETFNLGVDFLQQEIERTQAIGAK
                     DIVLHPGAHVGAGVDAGINKIIEGLNEVLTNDNNVRIALETMAGKGTEIGRSFEELARI
                     IDGVHNNERLSVCFDTCHTHDAGYNVKEDFDGVLNEFDKIIGVDRIKVVHVNDSKNDRG
                     AQKDRHENIGFGYIGFDALNYIVHHDSFKDIPKILETPYVGEDKKNKKPPYKLEIEMLK
                     QQQFDPELKNKVMQQ"
                     /name="deoxyribonuclease IV"
     gene            15287..16072
                     /locus_tag="AS858_RS00085"
                     /old_locus_tag="AS858_14900"
     CDS             15287..16072
                     /locus_tag="AS858_RS00085"
                     /old_locus_tag="AS858_14900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500168.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016887 - ATP hydrolysis activity [Evidence IEA];
                     GO:0042626 - ATPase-coupled transmembrane transporter
                     activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="WP_061491630.1"
                     /translation="MRGENTMTPVFELKNVNYYYDHKKVLENINIKINKGEFLAIVGPN
                     GAGKSTLLKLILGLLPLQSGEIFFEGIDFKNKKTSIKLSYVSQKANAFNSGFPASVKEV
                     VLSGLTKTKRLFQTFNSKDNEKVIKVLERLNISDLIHKNIAELSGGQQQRVMIARALIS
                     EPAVLVLDEPTNGIDAKHVSEFYNTLDQLKQEGITIILVTHDIGVVADTATEVACLNKH
                     LHFHGTTDEFKSLDEVEISKIYGHPVRFVDHQHNRECCN"
                     /name="metal ABC transporter ATP-binding protein"
     gene            16114..16976
                     /locus_tag="AS858_RS00090"
                     /old_locus_tag="AS858_14905"
                     /pseudo=""
     CDS             16114..16976
                     /locus_tag="AS858_RS00090"
                     /old_locus_tag="AS858_14905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500167.1"
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_process="GO:0030001 - metal ion transport [Evidence
                     IEA]; GO:0055085 - transmembrane transport [Evidence IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /name="metal ABC transporter permease"
     gene            16963..17369
                     /locus_tag="AS858_RS00095"
                     /old_locus_tag="AS858_14910"
                     /pseudo=""
     CDS             16963..17369
                     /locus_tag="AS858_RS00095"
                     /old_locus_tag="AS858_14910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500166.1"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /name="Fur family transcriptional regulator"
     gene            17657..18238
                     /locus_tag="AS858_RS00100"
                     /old_locus_tag="AS858_14915"
     CDS             17657..18238
                     /locus_tag="AS858_RS00100"
                     /old_locus_tag="AS858_14915"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500165.1"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]; GO:0004784 - superoxide dismutase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="WP_112368088.1"
                     /translation="MTKIPYAFDALEPHFDKETMEIHHDRHHNTYVTKLNAAVEGTDLE
                     SKSIEEIVANLDSVPANIQTAVRNNGGGHLNHSLFWELLSPNSEEKGTVVEKIKEQWGS
                     LEEFKKEFADKAAARFGSGWAWLVVNNGQLEIVTTQDNPLTEGKTPILGLDVWEHAYYL
                     KYQNKRPDYIGAFWNVVNWEKVDELYNATK"
                     /name="superoxide dismutase"
     gene            18359..20431
                     /locus_tag="AS858_RS00105"
                     /old_locus_tag="AS858_14920"
                     /pseudo=""
     CDS             18359..20431
                     /locus_tag="AS858_RS00105"
                     /old_locus_tag="AS858_14920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500164.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /name="penicillin-binding protein 2"
     gene            20544..20693
                     /gene="rpmG"
                     /locus_tag="AS858_RS00110"
                     /old_locus_tag="AS858_14925"
     CDS             20544..20693
                     /gene="rpmG"
                     /locus_tag="AS858_RS00110"
                     /old_locus_tag="AS858_14925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265708.1"
                     /GO_component="GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA]; GO:0000315 - organellar large
                     ribosomal subunit [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="WP_001265709.1"
                     /translation="MRVNVTLACTECGDRNYITTKNKRNNPERVEMKKFCSRENKQTLH
                     RETK"
                     /name="rpmG"
     gene            20902..21441
                     /locus_tag="AS858_RS00115"
                     /old_locus_tag="AS858_14930"
     CDS             20902..21441
                     /locus_tag="AS858_RS00115"
                     /old_locus_tag="AS858_14930"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500162.1"
                     /GO_function="GO:0030272 - 5-formyltetrahydrofolate
                     cyclo-ligase activity [Evidence IEA]"
                     /GO_process="GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="WP_000164545.1"
                     /translation="MTKNEIRKYILHKMKNFNKAEKRKADTWLRNQFFATEEYKEANAI
                     ALVLSFNHEVDTFSIIEQALMDHKRIFVPKMDYLNHQMTFKEIFNLKDIDVDNKGIYYP
                     TSKGETTNNLDLIVVPGVGFQDDGYRIGYGGGYYDRFLANYQTKTISLLYDFQITSFEP
                     ESFDQPVDKLIIYQAA"
                     /name="5-formyltetrahydrofolate cyclo-ligase"
ORIGIN
        1 acctatggca cctaaaaaaa acaagaaaaa accgatgaca gagaaaacaa tcacagtgcc
       61 taccggtgga gcaaaacata gaccttctag agtgacgaaa ttagacaatt agaaaaatca
      121 cttagatgat taaaacgagt agaattttga cctaaaaaaa atgctctgat aaatcttatc
      181 tgaacgtaca aagtttgcca aattctcaaa atgtcgaaaa agatttgact aaatcagcgt
      241 tccaatttga taaagatgaa gtaatcaatg gtatgatatg gtcagaaatt ttagctaaac
      301 caaaacaatt ataaaatttt ttgaaaacaa gcactatcgt aatggtagtt gcttgttttt
      361 ttacgttaag aaaaattaaa aaacaaagag aattttttcg agaaatatta gttatttaaa
      421 tttacagcaa aaaattgatt agtctaaaat tgaatctgct tttatgacaa ggtgaaaagt
      481 ataaatgatt attttaaatt aaagaaaaat gagtaagtca atgcaaagat gtttaaatca
      541 atcaattgca tgatataatt aagtagatat taaagcatca tagaatgaat ataaatgata
      601 tatgaaaagg agcgcgtgta tgcctggaat tatacaaata gacgatatga accaatctca
      661 agctttaatt ggaaataatg atgaacattt aaaagcaatt gaagagagtt tcgatgttgt
      721 catccatgca agaggacaag aagttgccgt taaaggtaca aaaatagaaa acgtagaaaa
      781 agcggaatca gtattaatca atttgctgaa ggttattgat ttaggtaata atattacaat
      841 taaagatgtt gaagcagcta ttaaaatggc gcataataac acaattcaac atctgttaga
      901 tttatatgat gaagagataa ctaaagatgc atttggtaag acgattcgtg cgaaaacgat
      961 ggggcaacgt atatatgtta atgccatgaa aaataatgat ttagtatttg gtataggtcc
     1021 tgctggtaca ggtaagacat tcttagctgt agtttatgca gcaaagcaac tccgtaaagg
     1081 tgctgttaaa cgtattgtat taacaagacc tgctgttgaa gcaggagagt cacttggatt
     1141 tttaccagga gatttgaaag aaaaggtaga tccatattta agacctttat atgatggtct
     1201 atatactgtt cttgggcgtg aacaaacaga gcgatttatt gaaagaggca ttatcgaaat
     1261 agcgccactt gcatatatgc gcggacgaac attagaagat gcatttgtaa ttcttgatga
     1321 ggcgcagaat acgacacatg cgcaaatgaa aatgttttta acaagactag gttttggctc
     1381 aaaaaatggg tagttactgg tgaccaaact caaatcgatt tacctaaagg tgttaaaagt
     1441 ggacttaagg aagcggtcag taggttacac aacgttaaag gtataagtat attgaaatta
     1501 gatcagagcg atgtagtcag acatccattg gtaagtaaga tcattgaaca ttatgaagga
     1561 gagaattaaa tgtttacgat agattttagc gatcacacag gcttagttaa agatgcttgg
     1621 tataaacaaa ttgaagattt attagaattt gctaaaaaag aagagcatat agaagacgat
     1681 gctgagcttt ctgttacatt tgtagataaa caagaaatac aagaaattaa tcgaacatat
     1741 agagataaag ataaagttac agatgtaatc tcatttgctt tagaagaaga tgagccagag
     1801 attgatttta gtggtcttga tataccacgt gttttagggg atataattat ctgtacggat
     1861 gtagcgcaag aacaagcaaa caattacgga cattcttttg aacgagaatt aggattttta
     1921 gcattacatg gatttttgca tctattaggt tatgatcata tgactgaagc ggatgaaaag
     1981 gaaatgtttg gtcgacaaga tacaatatta aacgcatatg gattaacacg agactaatta
     2041 tgaaaaggtt taaatatgca cttgatgggc tgaaaatctt aattcaaaaa gactataaat
     2101 ttcttttaca tgtgtttgca atgattgttg ctattgtctt tggtctcgta ctaaatatta
     2161 atcggattga gtggatattt atactcattg ctattgcatt agttctcact gttgaagctt
     2221 taaacactgc tattgaatat gttgtcgatt tagtgaccgt tgaatatcat gatttagcta
     2281 aatacgctaa agatattgcg gcttttagtg tacttatagt ttcaatatta gcatttatta
     2341 taggtttaat agtattttta ccacatttta tagcgttatt ttagggaggc atatatgagt
     2401 tatcaacctc attattttca aagaagttag aaaagcaaca acaagaatca tatcgccata
     2461 cagtcaattt aaagtagggg cttatttaaa aacgaaagac ggtagaactt tttatggtac
     2521 caatgtagaa aatgcttctt atccattatc gatatgtgct gaacgagcta gtttggtatc
     2581 ggcaatttct caaggataca gaccaggtga ttttgaatca ataactgtaa ccgtagatgc
     2641 agataaaccg tcatcacctt gtggtgcatg tcgtcaagtt ttgaaggaat tatgtgatga
     2701 tgatatgcct gtgtatatga caaatcataa aggagatatg gttatgatga cagtccgcag
     2761 agttactacc attttggatt tttcaggaaa ggatttagaa taaatgacag aacataaatc
     2821 aggatttgtt tcaattatag gtagaccaaa tgtaggaaag tcaacatttg ttaatagagt
     2881 gatcggccat aaaatagcaa tcatgtccga taaagctcaa acaactagaa ataaaattca
     2941 aggtgttatg acaagagatg acgcgcaaat tatattcatt gatacgccag gtattcataa
     3001 acctaaacac aaattaggtg actatatgat gaaagtcgct aaaaatacat tatctgagat
     3061 agatgcaatc atgtttatgg ttaatgccaa tgaggaaatt ggacgaggcg atgaatatat
     3121 tatagaaatg ttgaaaaatg ttaagacacc agtatttttt agtattaaat aaaatagatt
     3181 tagtgcatcc agatgaatta atgccaaaga ttgaagaata tcaaagttat atggacttta
     3241 cagagattgt acctatttca gcattagaag ggctaaatgt cgatcatttt attgatgttt
     3301 taaagacgta tttacccgaa ggacctaaat attatccaga tgatcaaatt tcagaccatc
     3361 ctgaacaatt tgtagtgggt gaaatcattc gtgaaaaaat ccttcatctt acaagtgaag
     3421 aaatccctca tgcgattggt gttaatgtgg accgtatggt taaagaaagc gaagatcgtg
     3481 ttcatatcga agcaactata tatgttgaaa gagattcgca aaaaggaatt gtcattggaa
     3541 aaggcggtaa aaagttaaaa gaagtaggaa aacgtgcgag acgtgatata gaaatgcttc
     3601 taggctctaa agtttactta gaattatggg tcaaagttca aagagactgg cgaaacaaag
     3661 ttaactttat tcgccaaatt ggttatgttg aagaccaaga ttaatcttaa aagtggtgaa
     3721 gataattgtt aatgcgccaa aaagggatta tcatcaaagc agttgattat ggtgaatctg
     3781 ataaaattat cacgatttta aaatgagcat ggtgcaaaag taccacttat ggcaaggcgt
     3841 gctaaaaaag ttaagacggg tttacaagcg caaacgcaat tgtttgttta tggtttgttt
     3901 atttacaatc agtggcgagg tatgggaacg ttaaattctg tagatgttat tagtcaacat
     3961 tataaattac aaatggacct ttacgtaagc agttatgccg ctctggcagc tgaaactatt
     4021 gagcgctcaa tggatgaagg tgacattgca ccatataact atcaattatt acaatttgtt
     4081 cttgaaaaaa tagaatcagg tacatctgca cagttaatgt cagtcgtagt tatgttaaag
     4141 tgcatgaaac gatttggttt tactgcatca tttaatcgct gtgctgtgag tggtaatgac
     4201 acacaagcag atttaatagg ttatagtttt aagtttgacg gtgcgatttc aaggcaagag
     4261 gcttctaaag atgtacatgc agttatatta tcgaataaaa cactatattt tattagatgt
     4321 attacaaaaa ttaccgatag ataaaatgaa ttcattgaat atccatcaag aaattattga
     4381 tgaaatgtca gatatcattt taatgttata tcgtgaatat gcaggtatgt tttttaaaag
     4441 tcagaaacta atcaaccaat taaaaagatt ggaacaataa cataaaataa taaaaggtat
     4501 tcaagtagcc acatagatgt gtttatttga ataccttttt gaatagaaaa gagatactgg
     4561 caattttact aaccagtatc tctttttata aattatatag ccaccacata tggtggaaag
     4621 tctttttaat tagaattttg ttttttcagt taagaaagct tctaactctg agattggcat
     4681 acgaacttgt tccattgaat ctctgtcacg tactgtaact tgattatctt ctaatgaatc
     4741 aaagtcgaat gttacacaat aaggtgtacc gatttcatct tgacgacggt atcttttacc
     4801 gatagattgt gattcatcga aatcgattga gaatttagaa cttaattgct caaaaatctt
     4861 aatcgcttcg ccagataatt tcttacttaa aggtaaaatc gctgctttat atggtgctaa
     4921 tgcaggatgg aagtgtaaaa ctgtacgtgc atctttacta ccttcaacgc cttcttcatc
     4981 atatgcatca cataagaaag ctaatgttac acgatctgca ccaagtgatg gctcgataca
     5041 atatggaata tatttttcgt tcgtttctgg atcatggtat ctgaaatctt caccagagtg
     5101 ttcagcatgt ttacgtaagt cgaagtctgt acgacttgcg ataccccata actcacccca
     5161 accaaatggg aatttatatt caatatcagt tgttgcattt gagtaatgag ataattcatc
     5221 ttcatcatga tcacgtaaac gcatattttc actgctcata tttaagcttg ttaaccagtc
     5281 acttgcaaaa gttttccaat aattttgcca ttcgatttct tctccaggtt tacagaagaa
     5341 ttcaagttcc atttgttcaa attctcttgt tctgaaaatg aagttacctg gagtgatttc
     5401 attacggaat gatttaccaa tttgaccgat accaaatggt aattttttac gcattgaacg
     5461 ttgcacgttt ttatagttta caaaaatacc ttgtgctgtt tcaggacgta agaaaatttc
     5521 atttgtagaa tcttcagtta caccttggaa tgttttaaac attaaattga attggcgaat
     5581 ttcagtccag ttagcagttt tacttacagg acaaacaata ccttcatcgt caataatttt
     5641 tttcatttgt tcaaaactta aaccatcggc aatgaagttt tcatcacctt taacatcttg
     5701 catataatct tcaattaatt tatcagcgcg atatcgaatt ttactatctt tattatcaat
     5761 cattgggtcg ttgaagttgt ttaagtgtcc tgaagcttcc catacttttg gattcattaa
     5821 gattgcagca tcgataccaa cgttaaacgg tgattgtgta atgaattttt gccaccaagc
     5881 ttttttaaca ttattcttta attcaacacc taaaggacca taatcccatg tgtttgataa
     5941 accaccgtaa atatcactac cagggaacac aaaacctctg tgttttgcta atgaaacaat
     6001 tgtatccata tcttttgcca taattacctc tcctcataca tgaaaacgcc ccatggaaaa
     6061 taacagcata gtaaatatgc tttacttcca tgggacgagt taatatttta aattgtatat
     6121 aatacaaaat aagttacgta tttaacccgc ggttccaccc aaattagtgt agtcactcgc
     6181 ttttatttta aaatgattcg ttgcgccaat cttattgtta agcttacact atccttaact
     6241 cgctgtacgt ttattctaat tgatagatta tttaaaggca agtaaaatta atgtgtttgt
     6301 gacatgaaag aaatatcggt ataataatag gtgaataaaa aaggggtgaa gacctataga
     6361 actcagtcaa agacaagaac gaatcatcga aattgttaaa actaaaggac ccattactgg
     6421 tgaacaaata gcagataagt tgaatttaac aagagcaacg cttagaccag atttagcgat
     6481 attaacaatg tcaggttttt tagaagcgcg tccccgagtt ggatattatt attcaggtaa
     6541 atcaaaaggc aaatttttta atgaaaaact tcgacaattt gaggttaagg actatatgtc
     6601 tcaacctgtt gtgctaagag agaatacaac agtttatgac gctatttgta caattttttt
     6661 agaagatgta agtacattat ttattattaa tgaagataac gattttgttg gtgtgtgttc
     6721 aagaaaagat ttattaagag cttcaatgat tggagcagat attcataaag tacctatcag
     6781 tgtaaatatg acacgtatgc ctaatgtcac ttatttagag gaaagcgaat tagtcatata
     6841 cgcagcagat agaatgattg aaaaagaaat tgattcgatt ccaattgtaa gaaaaaaaga
     6901 taatcaaaag tatgaagtaa ttggaagaat ttccaaaaca acaatagcta agttattagt
     6961 agcattatat aaagaatagg tgagaagtaa tggaaaaaat taaaattatc gtagcttcag
     7021 attctatagg tgaaacggca gagttagttg ctagggcagg tatttcacaa ttcaatccta
     7081 agcaatgtaa aaatgaatta ttaagatatc catatattga atcttttgaa gatgttgatg
     7141 aagtgattca agttgcaaaa gatacaaatg ctatcattgt ttatacactt attaaacctg
     7201 aaatgaagca atatatgagt gagaaagtag cagaattcca attgaagtct gtcgatatca
     7261 tggggccatt aatggattta ttatctgctt cggttgaaga aaaaccttat aatgagccag
     7321 gtatcgttca tagattagat gatgcatatt tcaagaaaat tgatgcgata gagtttgcag
     7381 ttaaatatga tgatggtaaa gatcctaaag gattacctaa agctgatatt gttttacttg
     7441 gtatttcgag aacttcaaag acaccattat ctcagtattt agcgcataag agttacaaag
     7501 ttatgaatgt accgattgta ccagaagtga caccgccaga tggcttatat gatattaatc
     7561 caaagaaatg tatcgcactt aaaataagtg aagaaaaatt aaatcgcatt agaaaagagc
     7621 gactaaaaat taggactagg tgacacagct cgatatgcaa cagaagcacg aattcaagaa
     7681 gaattgaatt actttgaaga aatcgtaagt gaaattggat gtcctgtcat tgatgtttct
     7741 caaaaagcaa tcgaagaaac agcaaacgat ataatccatt atattgaaca aaataaatcg
     7801 aaatgatttc atttttgtcg aaaattaggt ataatagtat aactaatgct taataggtga
     7861 tttaatttgc gaatagatca atcgatcatt aatgaaataa aagataaaac cgacatttta
     7921 gacttggtaa gtgaatatgt aaaattagaa aagagaggac gcaattatat aggtttgtgt
     7981 ccttttcatg atgaaaagac accttcattt acagtttctg aagataaaca aatttgtcat
     8041 tgttttggtt gtaaaaaagg tggcaatgtt tttcaattta ctcaagaaat taaagacata
     8101 tcatttgttg aagcggttaa agaattaggt gatagagtta atgttgctgt agatattgag
     8161 gcaacacaat ctaactcaaa tgttcaaatt gcttctgatg atttacaaat gattgaaatg
     8221 catgagttaa tacaagaatt ttattattac gctttaacaa agacagtcga aggcgaacaa
     8281 gcattaacgt acttacaaga acgtggtttt acagatgcgc ttattaaaga gcgaggcatt
     8341 ggctttgcac ccgatagctc acatttttgt catgattttc ttcaaaaaaa gggttacgat
     8401 attgaattag catatgaagc cggattatta tcacgtaacg aagaaaattt cagttattac
     8461 gatagatttc gaaatcgtat tatgtttcct ttgaaaaatg cgcaaggaag aattgttgga
     8521 tattcaggtc gaacatatac cggtcaagaa ccaaaatact taaatagtcc tgaaacacct
     8581 atctttcaaa aaaagaagtt gttacaactt agataaagcg cgtaaatcaa ttagaaaatt
     8641 agatgaaatc gtattactag aaggttttat ggatgttata aaatctgata ctgctggctt
     8701 gaaaaacgtt gttgcaacaa tgggtacaca gttgtcagat gaacatatta cttttatacg
     8761 aaagttaaca tcaaatataa cattaatgtt tgatggggat tttgcgggta gtgaagcaac
     8821 acttaaaaca ggtcaaaatt tgttacagca agggctaaat gtatttgtta tacaattgcc
     8881 atcaggcatg gatccggatg aatacattgg taagtatggc aacgatttac tgctttttgt
     8941 aaaaaatgac aaaaagtcat ttgcacatta taaagtgagt atattaaaag atgaaattgc
     9001 acataaatga cctttcatat gaacgttatt tgaaagaact aagtcatgat atttcgctta
     9061 tgaaatcatc gattttgcaa caaaaggctt taaatgatgt tgcaccattt ttcaatgtta
     9121 gtcctgagca attagctaac gaaatacaat tcaatcaagc accagccaat tattatccag
     9181 aagatgagta tggcggttac attgaacctg agccaattgg tatggcacaa tttgacaatt
     9241 tgagccgtca agaaaaagcg gagcgagcat ttttaaaaca tttaatgaga gataaagata
     9301 cattttaaat tattatgaaa gtgttgataa ggataacttc acaaatcagc attttaaata
     9361 tgtattcgaa gtcttacatg atttttatgc ggaaaatgat caatataata tcagtgatgc
     9421 tgtgcagtat gttaattcaa atgagttgag agaaacacta attagcttag aacaatataa
     9481 tttgaatgac gaaccatatg aaaatgaaat tgatgattat gtcaatgtta ttaatgaaaa
     9541 aggacaagaa acaattgagt cattgaatca taaattaagg gaagctacaa ggattggcga
     9601 tgtagttaca aaaatactat ttacagcaat tgttgctaaa ataaagaacg cattagcatg
     9661 tgattttaaa gaataatacg aataatgatt atgtcaaaat gtataagggt aaatgatagt
     9721 taccgcattt aaacaacact attgaaaaat aaatattggg attagttcca atttgtaaaa
     9781 taaaattaaa atatggatga attaattaag aatttagttt aaaatagcaa tattgaataa
     9841 atttcgaatg ttcatattta aaatcgggag gccgtttcat gtctgataac acagttaaaa
     9901 ttaaaaaaca aacaattgat ccgacattaa cattagaaga tgttaagaag caattaattg
     9961 aaaaaggtaa aaaagagggt cattaagtca tgaagaaatt gctgaaaaac ttcagaattt
    10021 tgatatcgac tctgatcaaa tggatgattt ctttgatcaa ttaaatgata ataatatttc
    10081 actagttaat gaaaaagata gttcagatac tgacgaaaac tgaatccaag tgatcttagt
    10141 agttaaatga agtcgtaaat acctgaaaga aattgggcgt gttacttatt aagtgcacaa
    10201 gaagaaatcg aattagccaa acgtattgaa caaggtgaag taaaaagaaa gaacttacgt
    10261 ttagttgtaa gtattgctaa aagatacgta ggtcgtggta tgttattcct tgatttaatc
    10321 caagaaggta atatgggtct tattaaagct gttgaaaaat ttgactttaa caaaggattt
    10381 aagttttcaa catatgcaaa tggtggatta gacaagcaat cactcgtgca attgctgacc
    10441 aagcacgtac gattcgtatc tgtgcaaaaa taataaaatt cgtgttcaac gtcaattatt
    10501 acaggaggtc ggatccagca ccagaagaaa ttggtgaaga aatggattta ccagcagaaa
    10561 aagttcgtga aattttaaaa attgcgcaag aacctgtttc attagaaatt ggtgaagaag
    10621 atgatagtca tttaggagac tttattgagg atcaggaagc acaaagtcct tcagatcatg
    10681 ctgcttatga attattaaaa gagcaattag aagatgtgct tgatacatta actgatagag
    10741 aagaaatgta ttacgattaa gatttggtct tgatgacggc agaacaagaa cacttgaaga
    10801 agttggtaaa gttttcggtg ttacacgtga acgtattcga caaattgaag caaaagcact
    10861 tagaaaatta aacatccaaa agtagtaaac gtttgaaaga ctttatggat taatttatat
    10921 aatttaatga ttgatacaag acatgaataa gcttatttat ttttagatta aatttaactt
    10981 gagtgaggtt ggtacattga ataatgttca acctcttttt tcataaagga gaataaaatg
    11041 atttcgttaa ataaccgatt aacgacggta agtcgatttt taaaaacaag gtacaatcgc
    11101 ggatattggc tcagatcatg cttatttgcc aatctatgca attcaaaacc atttatgcga
    11161 atgcggtatt gctggaagtt attcaaggcc cttttcaagc tgctgtgaaa aatgtagctg
    11221 caaaccaatt agtagataga attgatgtac gtttagggga tggcttaagt gttattcaac
    11281 ctgaggacgt aatcgataat atcacaattt gtggtatggg cggaccactt attgctaaaa
    11341 tttaaaagat gggcaagata agttaagtca acatccaagg ttgattttac aaagtaatat
    11401 ccaaactgaa aatttaagac aattacaaca attgaattat gaaataattg atgaaataat
    11461 aatggaagaa aaaggccata tttatgaaat tgttgtagca gaatattcta cagaattaat
    11521 agagctatca tctgatgaat tgaaattcgg accaaaattg ctgaacaaca aaatgaatat
    11581 tttataaaaa aaaaagagag ttagaagcac tttatcatat taaatcgaaa ctcaatactg
    11641 aacaacatca tcaacgttta gctcaaatta atgacgaaat tgctgtaatt gaaagggtgt
    11701 tatagtaatg aaaatagctg atttaatgac attgttagat catgtgccat ttagtactgc
    11761 tgaatcttgg gataatgtag gattgttaat aggtgatgaa gatgttgaag ttactggtgt
    11821 tttaacagca ttagactgta cgttggaagt agtaaatgaa gcaatcgaaa aaggttataa
    11881 tactattatt agtcatcatc ctctaatctt taaaggcgta acatcattaa aagctaatgg
    11941 ttatggtttg atcattagaa aactaattca acatgacatt aatttaatag cgatgcatac
    12001 aaatttagat gtaaatccgt atggtgtcaa tatgatgttg gcgaaggcga tgggtttgaa
    12061 gaacatttca ataataaata atcaacaaga tgtatactat aaagttcaaa catatatacc
    12121 taaggataat gttggaccat ttaaagataa gcttagtgaa aatggattag cgcaagaagg
    12181 taattatgaa tattgtttct ttgaaagtga aggaagaggg caattcaaac cagttggtga
    12241 agctaatcaa caataggaca aattgataaa attgaatatg tagatgaagt taaaattgaa
    12301 tttatgatag atgcatatca aaagtcaagg ctgagcaatt aattaaacaa taccatccat
    12361 atgaaacacc ggtatttgat tttattgaga taaaacaaac atccctttat ggacttggcg
    12421 ttatggcaga agtggataat caaatgacat tggaagattt cgcagctgat attaaatcta
    12481 aattaaatat cccaagtgtc cgttttgttg gtgagtctaa tcagaaaatt aaacgtattg
    12541 caattattgg tggttcaggt attggatatg aatatcaagc tgtccaacaa ggcgcagatg
    12601 tctttgttac aggtgatatt aaacatcatg atgccttaga tgctaaaatt catggtgtga
    12661 atttaattga tattaatcat tacagcgaat atgtgatgaa agaaggttta aaagcgttac
    12721 taatgaattg gttcaataca gaaaaaataa atttagatgt tgaagcatct acaattaata
    12781 cagatccatt tcaatatatt taaactaaaa tctcgggatt tctaaatttt gaaatttcga
    12841 ggttttaata tttttattta aaatagcaca tttatacttt ataatagtaa agatgaacat
    12901 ataaggaggc caaatcatgg caaaacatcc attcgaacaa tttaatctag aatctagttt
    12961 aattgacgct gtgaaagacc ttaattttga aaaaccaact gaaattcaga atcgaattat
    13021 tccaagaata ctaaagagaa caaatttaat tggtcaatct caaacgggta cagggaaatc
    13081 tcatgcattt ttattaccat taatgcagtt aattgatagt gaaataaaaa accacaagca
    13141 atcgtagttg caccaacaag agaacttgca caacaactat acgatgcagc gaacatttaa
    13201 gccaatttaa agctggtgtt tcagttaaag tttttattgg tggtacagat atagagaaag
    13261 atagacaacg ttgtaatgca caaccacaat tgattatagg cacccctact agaattaatg
    13321 acttagctaa aacgggacat ttacatgtgc acttagcatc atatttagtt attgatgaag
    13381 cggatcttat gattgactta ggattaattg aagatgtaga ttacattgct gcaagattgg
    13441 aagataatgc aaatattgcg gtgtttagtg ctacaatccc acaacagtta caaccatttt
    13501 taaataaata tttaagtcat ccagaatatg tagctgtcga cagtaaaaaa caaaataaaa
    13561 agaacatcga attctattta atacctacta aaggtgcagc taaagttgaa aagactttaa
    13621 atttaattga tatactaaat ccatacttat gtattatttt ctgtaatagt agagataatg
    13681 caaatgattt agcacgttca ctaaatgaag ctggtattaa agttggtatg attcatggtg
    13741 gcttaacgcc acgtgaacgt aaacaacaaa tgaaacgtat acgtaattta gaattccaat
    13801 acgttattgc cagcgattta gcatctcgtg gtattgatat tgaaggtgtt agtcatgtca
    13861 tcaattttga tgtggccaaa tgatattgac ttctttacgc atagagtcgg acgaactggt
    13921 cgtgggaatt ataaaggtgt agcaattacg ctttatagtc ctgatgaaga acacaatatt
    13981 tcattaatag aagatcgcgg ttttgtattc aatactgttg atattaaaga tggtgagtta
    14041 aagaagttaa agcgcacaat cagcgtcaag caagaatgcg caaagatgac catttaacta
    14101 atcaagtgaa gaacaaagtt cgaagtaaaa ttaaaaacaa agttaaacca ggttataaga
    14161 agaaatttaa acaagaagtt gaaaaaatga aacgtcaaga gcgtaagcaa tttagtaagc
    14221 agcaaaatag acaaaaacgt aagcaaaaca aaaaaggtta ggtgtgtttt atgttattag
    14281 gatcacatgt ttcaatgagt ggtaaaaaga tgttagaagg ttctgctata gaagcgcatg
    14341 aatatggtga aacaacattt atgatttata ctggtgcacc tcaaaacacg cgccgtaaaa
    14401 gtattgaaga tttaaatata actaaaggtc atgaagtgat ggaaaaatat ggtttatcta
    14461 atattgttgt tcatgcacca tacatcatta atattgcaaa tacaaccaaa ccagaaacgt
    14521 ttaatcttgg tgtagatttc ttgcaacaag aaattgaaag aacgcaagct ataggggcta
    14581 aagatattgt attacatcca ggtgcgcatg ttggagctgg tgttgatgcc ggaattaata
    14641 agattattga aggattaaat gaagttttaa cgaatgacaa taatgtacgt attgcgcttg
    14701 aaacgatggc aggtaaaggt acagagattg gtcgctcatt tgaagagtta gcacgtatta
    14761 ttgatggagt tcataataac gaacgtttat cagtatgttt tgatacatgt catacgcatg
    14821 atgctggata taatgttaaa gaggactttg atggcgtatt aaatgaattt gataaaatca
    14881 ttggagtcga cagaatcaaa gttgttcatg tcaatgattc taaaaatgac cgtggcgctc
    14941 aaaaagaccg acatgaaaat attggcttcg gttacattgg ttttgatgca ttaaattaca
    15001 ttgtgcatca tgatagtttt aaagatattc cgaaaatctt agaaacacct tatgttggtg
    15061 aagataagaa aaataaaaaa ccgccatata aacttgaaat tgaaatgtta aaacaacagc
    15121 aatttgaccc agaattaaaa aataaggtta tgcaacaata aaatgataat gctctcttca
    15181 agaaatgcga taaataaaac ttgaaggggg catatctctt tattttgtct aattttgagt
    15241 cgtaaacatt actgtttaca tatgttacta ggagttgtat agttgaatgc gaggtgagaa
    15301 tacgatgaca ccagtctttg aattgaaaaa tgtcaattac tactatgatc ataaaaaagt
    15361 gttagaaaat ataaacatta aaataaataa aggtgaattt ttagcaattg ttggaccaaa
    15421 tggtgctggt aaatcaacat tattgaagtt gattctaggg ttattacctt tacaaagtgg
    15481 tgagattttt tttgaaggta ttgattttaa aaataagaaa acatcaatta aattaagcta
    15541 tgtatcacaa aaagcaaatg cctttaattc aggtttccca gcaagtgtta aagaagttgt
    15601 tttaagcgga ttaacaaaga caaaacgtct tttccaaaca tttaatagca aagataatga
    15661 aaaagtgatt aaagtactag aaagactgaa tataagtgat ttaattcata aaaatatagc
    15721 agaattatca ggtggtcaac aacaacgtgt aatgattgct cgagcattga tttcagaacc
    15781 tgcagtatta gtacttgatg aaccaacgaa tggtattgat gcaaaacatg taagtgaatt
    15841 ttataatact ttagatcaat taaaacaaga aggtatcacc attatcttag ttactcatga
    15901 tatcggtgtt gtagcagata ctgctactga agtagcatgt ttaaataagc atttgcattt
    15961 ccatggtaca actgatgagt ttaaatcact tgatgaagtt gaaatttcaa aaatttatgg
    16021 acatcctgta cgttttgtcg atcatcagca taatcgagaa tgttgtaatt aataaagatt
    16081 tgagtttatt taaaatggaa aggcgtgtca caattgatag atgcattatt gaattttgat
    16141 tttatgaggt actctttaat tagtggtatc ttgataggtt ttattgcgcc tctaatcggt
    16201 gcttttatcg ttgttagacg actatcactt atagctgatg ctctaagtca tgtaacttta
    16261 ggtggtatat ctttcggtat gtttttactt actattatgc caacactagt atttattaat
    16321 ccaatgtggt ttggaatctt attcgcaata gtaggtgcgc ttctaattga aaaattaaga
    16381 acgtcataca ctgcttacca agaaattgct attccaatta taatgagtgc tggtatcgcc
    16441 ttgagtgcaa tcttcatttc attagctgat gggttcaatc aagaaattgt tggattgcta
    16501 tttggctcaa taagcgcagt gaatataagt gatttaacaa cgattattgt cattgccatc
    16561 atagttgttc tgtttattac attgttttat aaagaattat ttatatgtca tttgatgagg
    16621 aatatagtaa agtcattggc attcctaaat ggattcaatt tttatttatt gttattgtag
    16681 cgatggttat ttctgcctca atgcgtgttg tagggatact gttagtaagt gcgttaatca
    16741 cgttaccaat tgcaataagt atgcgaataa caaaaagttt taagcaattg atattactaa
    16801 gtgtattttt aggtgaatta tcagtaatat taggcttagt cctagctttc tatatggaca
    16861 tttctccggg tggtgtaatt gtagttctac ttgttatttt acttatgatt acaatggctt
    16921 atcagaaaat gcgaatgaag tttaaaaagg gagctaatat caatgaatac aaatgatgct
    16981 attaaaattt taaaagagaa cggtttaaaa tatacagata aacgtaaaga tatgttagat
    17041 atttttgtcg aagaagataa gtatataaac gcaaagtata tacaacaagt tatggatgaa
    17101 aattatcctg gaatttcgac acaatatata gaaacctgca cttatttaaa gatttaggaa
    17161 ttattgaaaa tacagaactt gatggtgaaa tgaagtttag aatcgcttgt acaaaccatc
    17221 atcatcatca ttttatctgt gaaaagtgtg gagatacaaa ggtaatagat tattgtccaa
    17281 tagatcagat aaaattatca ctacctggtg ttaatattca caaacacaaa cttgaagttt
    17341 atggtgtatg tgagtcttgc caagattaat ataaagaaat gagatttatg cacatttggt
    17401 cagatgtatg cataaatctc atttctttat attatagaag ataaaggttc atttcatact
    17461 ccgttcgtat gattttatgg caaatctgtt aactttttat atacaaaatg tttaattatt
    17521 tttgatttga gttatattaa atgagtagag aaaataataa gtagtagaat ttaagcaaat
    17581 tctttgttga accagtcact gcttgttatt atttacttac agacatttta ggaggatgat
    17641 tatttatggc ttttgaatta ccaaaatacc atacgcattt gatgcattag aaccacattt
    17701 tgacaaagaa actatggaaa ttcaccatga cagacatcat aacacgtatg ttacgaaatt
    17761 aaatgctgca gtagaaggta cagatttaga atctaaatct attgaagaaa ttgttgctaa
    17821 tttagacagt gtaccagcta acatccaaac tgctgtacgt aataatggcg gtggacattt
    17881 aaaccattca ttattctggg agttactttc accaaactca gaagaaaaag gtactgtagt
    17941 agaaaaaatt aaagaacaat ggggttcttt agaagaattt aaaaaagaat ttgctgacaa
    18001 agcagctgca cgctttggtt caggttgggc ttggttagtc gtaaacaatg gccagttaga
    18061 aattgtgact acacaagata atccattaac tgagggtaaa acacctattt taggtttaga
    18121 cgtatgggaa cacgcttatt acctaaaata tcaaaacaaa cgccctgact acattggcgc
    18181 attttggaat gtagttaact gggaaaaagt tgacgaatta tataatgcaa caaaataaag
    18241 tatgattact tgttcggtct cttaaatgag accgttattt ttttgtcaaa aagatagaaa
    18301 taatttctaa attcatatat gatttaaagt gaaagacttt gaatagaggt aggtagtttt
    18361 gttaaaaaga ctaaaagaaa aatcaaatga tgaaatcgtt caaaatacaa ttaacaagag
    18421 aattaacttt atatttggtg tgattatatt tatttttgca gtactagtac tacgtttagg
    18481 ttatttacaa atcgcacaag gctcacatta taaacaaatt ataaaaaatg atgaaaacat
    18541 tacagtgaat gagtctgtgc caagaggtcg tattttagac agaaatggga aagttttagt
    18601 tgataatgct tctaaaatgg ctattacata tactaggggt cgaaaaacaa cacaatcgga
    18661 aatgttggat acggctgaaa agttatcaaa gctaatcaag atggatacta agaaaattac
    18721 agaacgtgat aagaaagatt tctggattca gttgcatcct aaaaaagcaa aagcaatgat
    18781 gacaaaagaa caagctatgt tagcagatgg aagtattaaa caagatcaat atgataaaca
    18841 actgttatcg aaaatcggaa aatcacaatt agatgaattg tcttctaaag atttacaagt
    18901 tttagctatt tttcgagaga tgaatgcagg aacagtttta gatccacaaa tgataaaaaa
    18961 tgaagatgtc agtgaaaaag agtatgcagc agtttctcag caactttcca aattaccagg
    19021 tgttaacacg tctatggatt gggatagaaa atatccatat ggcgatactt taagaggtat
    19081 attcggagat gtatcgacac ctgctgaagg tattccaaaa gaattgacag aacattactt
    19141 atccaaagga tattcacgca atgatcgtgt tggaaaatct tacctagaat atcaatatga
    19201 agatgtattg cgtggtaaga agaaagaaat gaaatacaca acggacaaat ctggtaaagt
    19261 tacatcttca gaagtgttaa atcctggcgc tcgcggtcaa gatttgaaat taacgatcga
    19321 tatagatctt caaaaagaag tagaagcatt attagataaa caaattaaga agcttcgcag
    19381 tcaaggtgcc aaagatatgg ataatgcaat gatggttgta caaaatccta aaaatggaga
    19441 cattcttgcg cttgccggaa agcagattaa taagagtggt aaaatgactg attatgacat
    19501 tggtacgttt acttctcaat ttgcggttgg atcttctgta aaaggtggaa cattattagc
    19561 cggttatcag aataaagcta tcaaagttgg agaaacaatg gtcgatgaac cattacattt
    19621 ccaaggtggt ttgacaaaac gatcatactt caataaaaac gggcatgtaa ctattaatga
    19681 taagcaagct ttgatgcatt catcaaacgt atatatgttt aaaacagcat taaaattagc
    19741 gggagaccct tattattctg gtatggcttt accttcagac ataagttcac ctgcccaaaa
    19801 gctaagaaga ggattaaatc aagtaggctt aggtgtgaaa acagggatag atttaccaaa
    19861 tgaaacaaga ggtcaaatcg aaccattaac aaataatcca ggtaattatc tagatttatc
    19921 aattggtcaa tatgatacct atacaccatt acaattatca atatgtttca actatagcga
    19981 atgatggtta tagaatacag ccacacattg gattaacgat tcatgaatca actaataaag
    20041 atgaggttgg tccactcaag aagaaaatta atggcactgt cttgaacaag gttaataata
    20101 ctgaaaagga aatcaaacaa attcaagaag gattcaaaat ggcatttaat gataaagatg
    20161 gtactggata tgttagtttt aaagatacag tagtacctac tgctggtaaa acgggtaccg
    20221 cagaagtgtt ccaaaacgga gagccaagag ttaactctac ttatatagga tacgcgccaa
    20281 ttgatgatcc aaaattagcg ttttcaattg tatatacaaa tcagcctgta caccaccatg
    20341 gttaacaggt ggagacttag gtagagatgt aattaactac tactttaagc agttaggtaa
    20401 aaatgataaa aataaagaca aagacaaata aaatttaacc tgacgattgt gtagcgcatg
    20461 gttgtaaaat tttaactttg caaatattat agatgttggt ataataataa agtcgtattt
    20521 agaaatgata aggaggaata accatgcgcg taaacgtaac tttagcttgt acggaatgtg
    20581 gtgacagaaa ctacattaca actaagaaca aaagaaataa tccagaacgt gttgaaatga
    20641 agaaattctg ttcacgtgaa aacaaacaaa ctttacaccg tgaaacaaaa taatcattaa
    20701 aattaaattt aaattaacaa taaaaaaggt gaaatctcaa aataagaggt ttcacctttt
    20761 taattatgca cacgtatgaa atgataaaag attttcaatt gaaataataa attttagaat
    20821 tgtcgcataa ttcatcatga caacataatg acatgtattg ttattaacga tataatagaa
    20881 ttgaataaag tgggtgataa tgtgactaaa aatgagatta gaaaatacat tttacataaa
    20941 atgaagaatt ttaataaagc tgaaaagcga aaagcagaca catggttaag aaatcaattt
    21001 tttgcaactg aagaatacaa agaagcaaac gcaattgcgc tagttctttc ttttaatcat
    21061 gaagtagata ctttttctat tattgaacaa gccttaatgg atcataaacg tatttttgta
    21121 ccgaaaatgg attatttaaa tcatcaaatg acttttaaag agatatttaa tctcaaagat
    21181 attgatgtcg ataataaggg gatttactat ccaacttcaa aaggtgaaac aacgaataac
    21241 ctagatttaa ttgttgttcc tggtgttgga tttcaagacg atggatatag aattgggtat
    21301 ggtggtggct attacgacag gtttttagct aattatcaga caaagacaat aagcttatta
    21361 tacgattttc aaataacatc atttgaaccg gaatcattcg atcaaccagt cgataaattg
    21421 attatatatc aagcagcata gtggaggact aaatgaacat agacaaacaa ttttggaaaa
    21481 caatatatta ttggattagg tacttgaatt ttgatattgt cagtagggaa aaagatgacc
    21541 aagaaatttg gttagcccat aaaaaaaaaa aacaagtagt catttttaaa acaacatatc
    21601 aagtctaccc aagaaatacg ttttgacaaa gcgaaagtgc ttgaacacaa agatgaaata
    21661 gcaaatttta tttctttcga accacaaagt tttgaatttt attattttac agaatcggaa
    21721 ttttcagaag acaattaaat gaagtttcgc caattagaat taaattcaat gttataagac
    21781 acacaaaaga tttgataaag catatgccga atatattttt ggctagactt atttcagaag
    21841 ataatgataa aaagacatat atgttctata aacgcaaagt attaaccgat aactttttag
    21901 ataaatatat gcagaaattt tcaccggcaa catacacaat aatatttgta aatgtcttaa
    21961 tatggttatg tatgatttta tatttaaata atttttcgga tgtaaaatta ttagatgttg
    22021 gcgggttagt gcattttaat gt
//
