LOCUS       NZ_CP012980            20720 bp    DNA     circular CON 21-NOV-2023
DEFINITION  Staphylococcus aureus strain ST20130940 plasmid pST20130940,
            complete sequence.
ACCESSION   NZ_CP012980
VERSION     NZ_CP012980.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN04166494
            Assembly: GCF_001611325.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 20720)
  AUTHORS   Trouillet-Assant,S., Lelievre,L., Martins-Simoes,P., Gonzaga,L.,
            Tasse,J., Valour,F., Rasigade,J.P., Vandenesch,F., Muniz
            Guedes,R.L., Ribeiro de Vasconcelos,A.T., Caillon,J., Lustig,S.,
            Ferry,T., Jacqueline,C., Loss de Morais,G. and Laurent,F.
  TITLE     Adaptive processes of Staphylococcus aureus isolates during the
            progression from acute to chronic bone and joint infections in
            patients
  JOURNAL   Cell Microbiol 18 (10), 1405-1414 (2016)
   PUBMED   26918656
REFERENCE   2  (bases 1 to 20720)
  AUTHORS   Trouillet-Assant,S., Lelievre,L., Martins-Simoes,P., Almeida,L.G.P.,
            Tasse,J., Valour,F., Rasigade,J.-P., Guedes,R.L.M.,
            Vasconcelos,A.T.R., Cailon,J., Lustig,S., Ferry,T., Jaqueline,C., de
            Morais,G.L. and Laurent,F.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-OCT-2015) Labinfo, LNCC - Laboratorio Nacional de
            Computacao Cientifica, Rua Getulio Vargas 333, Petropolis, RJ
            25651070, Brazil
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.9
            Genome Coverage                   :: 109x
            Sequencing Technology             :: 454
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/21/2023 11:02:52
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,651
            CDSs (total)                      :: 2,569
            Genes (coding)                    :: 2,501
            CDSs (with protein)               :: 2,501
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 34 of 68
            Pseudo Genes (incomplete)         :: 32 of 68
            Pseudo Genes (internal stop)      :: 20 of 68
            Pseudo Genes (multiple problems)  :: 17 of 68
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP012980.1.
            Bacteria available at the French National Reference Center for
            staphylococci (CNR Staphylocoques) in Lyon, France.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..20720
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="ST20130940"
                     /isolation_source="83-year old woman with a hip prosthesis
                     infection"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="pST20130940"
                     /geo_loc_name="France"
                     /collection_date="2010-01"
     gene            1..861
                     /locus_tag="SAST40_RS13360"
                     /old_locus_tag="SAST40_02755"
     CDS             1..861
                     /locus_tag="SAST40_RS13360"
                     /old_locus_tag="SAST40_02755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000145511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_000145511.1"
                     /translation="MTGETVVYKNEMNLVPLRRFTATEINLFFAMCNKLKEQDTNTLRL
                     SFDELKKLSNYSPETRNINRFANDLDNVYKKMLNLTIRYEDDDVIERFVLFNHYRIHKR
                     EQYLEISTSSNLKHILNSITNNFTKFELKEMTRLKSTYSKNMFRLLKQYKHTGYLKIHI
                     DDFKNRLDIPKSYRMTDINKNVFKPIIIELGSIFNNLTINKIKAKKGRKIEWIEFTFDA
                     EKRIHNKRQPQMSKIDKSRQYVRREKTPKWLEERSYEKQPQKDYDPQLEKEREDFLKQL
                     ELNWE"
                     /name="replication initiation protein"
     gene            948..1289
                     /locus_tag="SAST40_RS13365"
                     /old_locus_tag="SAST40_02754"
     CDS             948..1289
                     /locus_tag="SAST40_RS13365"
                     /old_locus_tag="SAST40_02754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761340.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000761341.1"
                     /translation="MKLAEAIKEQRELKGWSQEELANILKVSRQSVSKWESAKNYPSLD
                     ILIAMSDLFGISLEHLIKGDARFKKVILEGNYRESNRVPSIVDFLYDFWWLFFPVAGFL
                     VWAIHSFMG"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(1528..1599)
                     /locus_tag="SAST40_RS14255"
     CDS             complement(1528..1599)
                     /locus_tag="SAST40_RS14255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_106873653.1"
                     /translation="MNEILVHIMTTAISGCLVTLFGY"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            1748..1933
                     /locus_tag="SAST40_RS13370"
                     /old_locus_tag="SAST40_02752"
     CDS             1748..1933
                     /locus_tag="SAST40_RS13370"
                     /old_locus_tag="SAST40_02752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000466619.1"
                     /translation="MFGDQRQEATKYVIKEGYQDIYFLNKNGEWYYFEVRSVWRGKHII
                     RVKDGLLGWRKEIVTE"
                     /name="hypothetical protein"
     gene            complement(2152..2895)
                     /locus_tag="SAST40_RS13375"
                     /old_locus_tag="SAST40_02751"
     CDS             complement(2152..2895)
                     /locus_tag="SAST40_RS13375"
                     /old_locus_tag="SAST40_02751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843758.1"
                     /translation="MKSVKRLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESATEDKQKKESDNINFESKSDAQIVEILKNQINTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNAR
                     QNVDAQEKTYTTSPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAQREDVSANPND
                     NDSDIEEKSEETEPKKGFWSRLFGN"
                     /name="DUF536 domain-containing protein"
     gene            3306..3982
                     /locus_tag="SAST40_RS14310"
                     /pseudo=""
     CDS             3306..3982
                     /locus_tag="SAST40_RS14310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /name="replication initiator protein A"
     gene            <3993..4275
                     /locus_tag="SAST40_RS14405"
                     /pseudo=""
     CDS             <3993..4275
                     /locus_tag="SAST40_RS14405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199895.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            5485..6102
                     /gene="cadD"
                     /locus_tag="SAST40_RS13390"
                     /old_locus_tag="SAST40_04563"
     ARG             5486..6099
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="99.51"
                     /coverage="100.0"
     gene            6121..6468
                     /locus_tag="SAST40_RS13395"
                     /old_locus_tag="SAST40_03484"
     CDS             6121..6468
                     /locus_tag="SAST40_RS13395"
                     /old_locus_tag="SAST40_03484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119691.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNQEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            6628..6720
                     /locus_tag="SAST40_RS14265"
     CDS             6628..6720
                     /locus_tag="SAST40_RS14265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            6932..7906
                     /locus_tag="SAST40_RS13400"
                     /old_locus_tag="SAST40_02772"
     CDS             6932..7906
                     /locus_tag="SAST40_RS13400"
                     /old_locus_tag="SAST40_02772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="WP_000072391.1"
                     /translation="MSNTKIKYQIFISSTYLDLIEERQAVVEAVLNSNNIPAGMELFNS
                     SSKSQWEIITQWINESDAVILLLGSSYGTIDSEENISYTEMEYNFAKSLGKPIYVFEMN
                     KASTESAEKSKKLDEFKTKVKENRLISPNINDISELKSKVSQTLMQSVPSEIKENSGWI
                     RVQDCGKNVKKLKKLDAIQRDLDTYDFLKEELYKIFMYVKTFYFQHTPFDDSYIEDIEN
                     YLLNYENNPHKSFMKIKVYDYKNFLKHLKNILILIKQGKKPLAQAGHFKLSFYEEDLKL
                     LQKNYKTTLVDIKGLNKHFYKECDRCLKAYNIFIEGINKHLYE"
                     /name="DUF4062 domain-containing protein"
     gene            complement(8026..8841)
                     /locus_tag="SAST40_RS13405"
                     /old_locus_tag="SAST40_02771"
     CDS             complement(8026..8841)
                     /locus_tag="SAST40_RS13405"
                     /old_locus_tag="SAST40_02771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019467708.1"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_000164958.1"
                     /translation="MTKNQNFIETKEYKRFAEFCDACIKYQYIGICYGQPGVGKTLSSR
                     YYTNWDTIEKQVNHRGWEDLASKTTDDILSVDKIFYNAPAEKQTKLRNDLYSITAIIDL
                     GQKLHVVNKYGHEHSKHYSDMFKYIDLIIVDEIDRLKVQHLEQLRAIYDEHNLAMIFIG
                     MPGIEKKLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWQDLGFDLKLEDFTDYEAIT
                     TIIKITKGNFRLIHRLFAQIDRIMDINGLDKISTEVVETARDSLVIGIR"
                     /name="AAA family ATPase"
     gene            complement(8834..10277)
                     /locus_tag="SAST40_RS13410"
                     /old_locus_tag="SAST40_04131"
                     /pseudo=""
     CDS             complement(8834..10277)
                     /locus_tag="SAST40_RS13410"
                     /old_locus_tag="SAST40_04131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790716.1"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /name="DDE-type integrase/transposase/recombinase"
     gene            complement(10249..10842)
                     /locus_tag="SAST40_RS13415"
                     /old_locus_tag="SAST40_02768"
     CDS             complement(10249..10842)
                     /locus_tag="SAST40_RS13415"
                     /old_locus_tag="SAST40_02768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690636.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690638.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNQKDLNLLKTLYDNGTPI
                     KTIAEQWHVSRTTIYRYLNKLEDKEDEKQGEVSN"
                     /name="recombinase family protein"
     gene            complement(11106..11486)
                     /gene="blaI"
                     /locus_tag="SAST40_RS13420"
                     /old_locus_tag="SAST40_03482"
     ARG             complement(11110..11486)
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="99.21"
                     /coverage="100.0"
     gene            complement(11476..13233)
                     /gene="blaR1"
                     /locus_tag="SAST40_RS13425"
                     /old_locus_tag="SAST40_04303"
     ARG             complement(11480..13233)
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.38"
                     /coverage="100.0"
     gene            13340..14185
                     /gene="blaZ"
                     /locus_tag="SAST40_RS13430"
                     /old_locus_tag="SAST40_04302"
     ARG             13341..14182
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            14554..15162
                     /locus_tag="SAST40_RS13435"
                     /old_locus_tag="SAST40_02763"
     CDS             14554..15162
                     /locus_tag="SAST40_RS13435"
                     /old_locus_tag="SAST40_02763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002436987.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001566953.1"
                     /translation="MIVGYARVSSNDQNLERQLENLKTFCAEKIFTEKQSGKSIENRPV
                     LQEALNFLRMGDRFVVESIDCLGRNYDEVIHTVNYLKDKEVQLMITSLPMMNEVVGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRI
                     IYHRVVEMLEEGQSISKIAKEVNITRQTIYRIKNDNDLI"
                     /name="recombinase family protein"
     gene            15576..15869
                     /locus_tag="SAST40_RS13440"
                     /old_locus_tag="SAST40_02762"
     CDS             15576..15869
                     /locus_tag="SAST40_RS13440"
                     /old_locus_tag="SAST40_02762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="WP_000726502.1"
                     /translation="MKKKFVSSCIASTILFGTLLGVTYKAEAATVHVAGGVWSHGIGKH
                     YVWSYYSHNKRNHGSTAVGKYSSFSGVARPGVQSKASAPKAWGGNKTFYSLH"
                     /name="lactococcin 972 family bacteriocin"
     gene            15944..17878
                     /locus_tag="SAST40_RS13445"
                     /old_locus_tag="SAST40_02761"
     CDS             15944..17878
                     /locus_tag="SAST40_RS13445"
                     /old_locus_tag="SAST40_02761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001670421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="WP_000713729.1"
                     /translation="MKKFKLFLDFSTLLLISGLLFLFFFKENEEIIPESSNILTISNWD
                     KSNSKSKVLDVIESGAKNQNIQIIKSVKDFDNKKEFFVFNSKRNNSDFIRNKTSLLTPS
                     DLLNREIKGKYYIIGEHFNVEELTSELKKAGLTSEVEYINRNILFFELVIDNDLLVPFI
                     FLGVLYLLYFLYDRGYNLKFYAIQKLHGFSTTRIIFHNIHIKIIYWLVLTAIFFIANIL
                     IIHIANLELDFLMFIRRFIVLLFVFACITTLLWLISYSLLLKLSIPLILKGKKGYKFSI
                     FMGTFTKCIMVLILSFLLAQNLNAYTKLKNIYDSEKIWQKLDNYYTLEISPNIRNSEEK
                     QILETNIYNLIKKSEQLGGLLLKNNNIANPDKNNYIPENGNVFFINNNFLNFYKNINHD
                     FKMIDNHSDKINVFIPPRLQYQKSEIQKNHQGWIDFQKQQNKKVDVQVLSKNVSVFSFD
                     RTTNLKFGYLDSPIVMLLTLDDLTGDFYLAAVSQGGYLFKDLDTLKQLLKDNHLEEEIS
                     GITNYKDSVLNELNETKTKMIITIVTIIINVFILLIATVFETIQYFSWNKKQLLLRKIH
                     GYSLFSSNVRYLTISILLSIMLAYTTHILFGSKILLFIIMSIAIIQHLLQIAYIKYLEK
                     YFKDLMREI"
                     /name="bacteriocin-associated integral membrane family
                     protein"
     gene            17882..18193
                     /locus_tag="SAST40_RS13450"
                     /old_locus_tag="SAST40_03040"
     CDS             17882..18193
                     /locus_tag="SAST40_RS13450"
                     /old_locus_tag="SAST40_03040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="WP_000831610.1"
                     /translation="MKRTLIIVTIVLLIIILSLLLVRNEHLDRFNPLLKEKVSYAKVPK
                     DTQDYRNITVYSKNGEKKSYKLDFLGYDPTKEYVKVNHKGKYVRSIEYITKDIPSFLK"
                     /name="YxeA family protein"
     gene            18205..18831
                     /locus_tag="SAST40_RS13455"
                     /old_locus_tag="SAST40_02759"
     CDS             18205..18831
                     /locus_tag="SAST40_RS13455"
                     /old_locus_tag="SAST40_02759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000593103.1"
                     /translation="MIKLENVFVKKGNKNILDGCNFNFEKGKSYALVGESGAGKSTLLN
                     IIAGFEDVSQGSIYIEDKLLKKKVDFYRYTLGYLFQNFALLENQTISQNLDLALKFKKN
                     KKDNMNLKKEVLKKVGLDLDIKRIVSSLSGGEQQRVALARLILKDPKIILADEPTGSLD
                     TKNGKIVIDLLLKLLDENKTMIVVTHDLELAKRFDVIVNISELRS"
                     /name="ABC transporter ATP-binding protein"
     gene            19069..19698
                     /gene="mobV"
                     /locus_tag="SAST40_RS14410"
                     /old_locus_tag="SAST40_04134"
                     /pseudo=""
     CDS             19069..19698
                     /gene="mobV"
                     /locus_tag="SAST40_RS14410"
                     /old_locus_tag="SAST40_04134"
                     /inference="COORDINATES: protein motif:HMM:NF013258.3"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /name="mobV"
     gene            19792..20337
                     /locus_tag="SAST40_RS13470"
                     /old_locus_tag="SAST40_03479"
     CDS             19792..20337
                     /locus_tag="SAST40_RS13470"
                     /old_locus_tag="SAST40_03479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001805533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000273005.1"
                     /translation="MYEIKTKNVGGWFHKEKQETGNIVITKTDFEKYTKQIKAAQMILD
                     DYECIKSGKSLKKAEKQNESLVNELTSVHMENEKLVEEFNDLAQRYNYLLSENEKKDKE
                     LNYTLKLFNQVFKIIKSMMKEERYHTLINHIDNHLDNSKIREVMTIDNNDEQFFKKKYQ
                     AQEREIIFKEDREDGYTL"
                     /name="hypothetical protein"
     ARG             13341..14185
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     BGC             10576..20720
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          4333..4480
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="81.333"
                     /coverage="100.0"
                     /evalue="2.96e-25"
     Typing          2..861
                     /name="rep_cluster_2214"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(2153..2895)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.866"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          19070..19344
                     /name="MOBV"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="94.565"
                     /coverage="100.0"
                     /evalue="4.71e-46"
ORIGIN
        1 atgacaggag agacagttgt atataaaaat gaaatgaatt tagttccatt aaggcgattt
       61 acagctactg aaattaattt attttttgcg atgtgtaata aattaaaaga gcaagatact
      121 aatacattac gtttgtcttt tgatgaatta aaaaaattaa gtaattatag tccagaaaca
      181 cgtaatatta atagatttgc taatgattta gataatgtgt ataaaaagat gttgaattta
      241 accattagat atgaagatga tgatgtaata gaaagattcg ttttattcaa tcattataga
      301 atccataagc gagaacaata tctagaaata tcaacttctt caaatttaaa acacatattg
      361 aattcaatta ctaataattt tacaaaattt gaattaaaag aaatgactag gcttaaatct
      421 acatattcta aaaatatgtt tagattactt aaacaataca aacatacagg ctatttaaaa
      481 attcacatcg atgattttaa aaatcgttta gatataccta aatcttatcg tatgactgat
      541 attaacaaaa atgtttttaa acctattatt attgaattag gttctatatt taataatctt
      601 actatcaata aaatcaaagc gaaaaaaggg cgtaaaattg aatggataga gttcacattt
      661 gacgctgaga aacgcattca taacaaacga caacctcaaa tgtccaagat agataaatca
      721 agacaatatg tgaggcgtga aaagacgcct aaatggttag aagaacggtc atatgaaaag
      781 caacctcaaa aagattacga cccacaatta gagaaagaac gagaggattt tttaaaacaa
      841 cttgaactga attgggaata acgcaacttt tcgttgcgag ttggttaact aaaagtatcg
      901 tgacttttca attattttaa ttatagtttg agttaaggag tgattttatg aaattagctg
      961 aagctataaa agaacagaga gaattaaaag gatggtctca agaggaatta gccaatatat
     1021 taaaggtttc cagacaaagt gtttctaaat gggaaagtgc caaaaactat ccttccttag
     1081 atattttgat tgctatgagc gatttattcg gaatctcttt agagcattta attaaaggag
     1141 atgcacgttt taaaaaagtt attttagagg gaaattatag agagagtaac agggtacctt
     1201 ccatagttga ttttctttat gatttttggt ggcttttctt tcctgttgcc ggatttttag
     1261 tttgggccat tcattcgttc atgggttgat tttaaaatca aaatttaatg cacatcaggc
     1321 aatatgaaaa aggaaagtat ttttacgaca ccttgaaatg tattgataag aatagaagag
     1381 tttacaaaag gcaatatgaa atatatacta aaagtaacaa gaatttcgtt tgtaaacgca
     1441 caaaaccccg aactattcgc cgtagttcgg ggttttgtgg tgaattggct ttaatcgtct
     1501 atattatttt ttatcacgtt tatggagcta ataaccaaat aacgtaacga gacaaccact
     1561 gattgccgtt gtcatgatgt gaacaagaat ttcattcata aatcgcacct cctctctacg
     1621 ccgaattgac atctgagaga tagacgacct tcacattata acaaatctct ccttccatga
     1681 aataacatga atattaataa atgttgttat atattaaaga taaataaata taagggtggg
     1741 attgataatg tttggcgatc aaagacaaga agctacaaaa tatgtcatta aagaaggtta
     1801 tcaagatatt tatttcctca acaaaaacgg ggaatggtat tatttcgaag taagaagtgt
     1861 ctggcgtggc aaacatatta ttagagttaa agatggtttg ttaggttgga gaaaagaaat
     1921 agtaactgaa taaagataca aaatacttgc caatgcaaaa gaatgaaaac gcgtcaaatc
     1981 aacgatgtat aaaagatgca taaaagataa tgaaagtaaa aagccataaa tgccgtcata
     2041 taggcattta tggctttttg tttggttaac ataatcgatg attatcagaa gttcaattca
     2101 cataaaaaag cacggctaat ttatgaactt gtcgtacctt tttaattaaa attagttacc
     2161 aaatagacga ctccaaaacc cctttttagg ttccgtttct tcactctttt cttctatatc
     2221 actatcattg tcatttggat tagctgaaac gtcttctctt tgtgcttctt caccttgtgt
     2281 actttcgtcg ctttgacttc cagatatatc cttatattga atctctgttt ctttagtttc
     2341 ttcctgatct cggttaatat ttacaggact agtagtatat gttttttctt gtgcatcaac
     2401 gttttgtcta gcgttagtag atgtatcaaa gggataatta aggtgttttt ctttttctaa
     2461 ttgattttct aatttttgaa tctttttatt actctctaat gccagaactt gctgattctc
     2521 aagcaatttt gatctttctt gcaactcttt tctgtaaaat tcaattgttg tttcatgacg
     2581 actttcttgt ttttcaattt gattatttaa agtattaatc tgatttttaa gtatttctac
     2641 tatttgagca tcgcttttag attcaaaatt aatattatcc gactcttttt tttgtttgtc
     2701 ttcagtagca ctttcaaaac catatttctt tttattttca tttactcttt gaatgatttt
     2761 ttctatatcg gtatcttctt taataaacga agtgttttcc tgttttattg tctctatatt
     2821 caatctctta atattattaa aaatcgtttg cttactaacc cctaattctt cactcaacct
     2881 ttttacactt ttcatatcat caacccttta taaaatgttt ataaaccctt agtaaaatat
     2941 tataagctta taacgattaa taataaagta atcgacaaat aaaaatataa attcgccaac
     3001 ctttttatca agggtttgta aagggtttat ggtgtttatc aaaggtttat aaacctatat
     3061 tttccctttt ttaagtttat tcaaagtgct ataataacct taatataaca aaaaccccaa
     3121 ctactggtaa tagtcggggt ttggtaataa aacgtttaga aactgtttat ttatataatt
     3181 ttcgatactt agattatata atgaataata tcttagtgca agcacctaga ttattaaata
     3241 aacacaaaaa atgtaagcgt tttattacct cttaccaaac taaaattcgg aaagaggttt
     3301 ttattatgtc aattaaactt tacaacataa atgaggaata cagagaaaag ttttatcaaa
     3361 taccgaaagt attttttaca aatcctaaat atatcaagtt atccaatgat gcaaaaatgg
     3421 catggggtat tcttagagat cgtttagatt tatcaattaa aaatggttgg gttgattcta
     3481 aaacaggtaa tatttatttt tattacaaaa atgaaaaccc acaaaatata ttaaattgta
     3541 aaaaagataa agtaattaaa ataaagaaag aacttaattg aagccgaatt actactacaa
     3601 gaaagacaag gtttaaataa gacaaataaa ctttatttag ttaaaccaga agtaacagaa
     3661 gatgatattt ataaaattca aaagcaagaa aacactgttg agagcagcaa tggcaaggaa
     3721 gtcggaaaaa ccgacttcaa gaagtcgata aaacagaatc taatgatact gaacttagct
     3781 atactgaatc taacaatact gaaataaatg atatgaatga cttgaatgat atagagtccg
     3841 aaaatgaaat tagtaatcat tcaagtcaat gcaaggttat ttaatgcaaa caattttaac
     3901 tgaatttgaa gaaacacatg cactttatat gcgccgtaaa aacatgaaac aatataatat
     3961 ctttaatcaa tcattcaaat gattttataa caatcaaaga tacatcaaaa tatttcgtta
     4021 aatcatctga ctttttaact gatagcgatg aaaaaatcaa gaaattgtca gtgatctaga
     4081 aaaagatttg tatcgaaaac gtatgttaag ttatggtgga ttgcttaaat aaaaacataa
     4141 aattttaaac ttagacgatg ctgaagatgg caatttaatt aatacaagtg atgaagataa
     4201 aatagcaaat gaagaagaaa aggcacattc gattacggca attttgaaaa gcaaaattat
     4261 tatttaaggc attagtgata actgatgtct ttttttatta cttttttgta aaaaaagtgc
     4321 tgtcttattt ttgtgacaaa tgctgtatgt agtgtcacaa aagtgtgaca cttgagcttt
     4381 ttatgacccc acacaaaaac attttcgaag ccttgaaata tctggctttg ccagatcccc
     4441 cattcattga tggggacaaa tttcccttat gctcttacgg agattttaga gttaaattaa
     4501 aatttctaag tttttgataa gaaaagccct gcaggaattt agaagaacgt ggggaagttt
     4561 taaagaattt tatgctaatt tttaatttgc atgtaaatgg gcagtgtcta aaaaatagtt
     4621 attgtttttg ctcaaatttt tgtttttgaa aatagcatat atttatttgg ctcatatttg
     4681 cgttttaaaa gcgtatataa gttttagata taaaactata tgaatcaccc ctaaatcttt
     4741 aaaatgccct cttaaaattc aaaataaggg cataaaaaat aaaagccccc ccagataaag
     4801 tgaggtagct ttttctttcg acgccgtatc gtcgatgtaa ttcaaaaaag ttatgggcta
     4861 taaatctaca tcactttttc aagaatgtag tagcaatatt caacgcaaat taatttttat
     4921 aactgctcgg aatatctcaa gccgtttctt taattttgaa ataaaaaaat cgacgaaggt
     4981 cgattacgtt tttgcacatg tcgatttatc cgacgtataa gtgcgccctt acgggattta
     5041 actagattat aacgacgaat tttagacctg taaagcaata acaattaggt ctaccaggta
     5101 gataaagtgt acaaagtaga accgaaaaag ttatttattt tgaagatttt tcgtagatat
     5161 aatttgctaa taaacttcct aaaactgaat aaagaaaaat agttaaactc atgtaatcac
     5221 tccataattc tgaagtgtct ccatgtctac gcatagacac gcatttatgc cgagaaaatt
     5281 tattgtgcgt tgagaagaac ccttaactaa acttgcagac gaatgtcggc atagcgtgag
     5341 ctattaagcc gaccattcga caagttttgg gattgttaag ggttccgagg ctcaacgtca
     5401 ataaagcaat tggaataaag cacctatgat tatttaaaaa tataagttat aatacattca
     5461 aaaatatttt gaatgaggtg tattatgatt caaacggttg ttgctgctgc tgttctttat
     5521 attgctacag cagttgattt attagtaatt ttattaatat tttttgctag agcaaagact
     5581 agaaaagaat atagaaatat ttatgttggt caatatttag ggtctattat tttaatatta
     5641 gttagtttgt ttttagcttt tgtattaaat tatgttccag aaaagtggat attaggttta
     5701 ttgggtttaa taccaattta tcttggaatt aaagtggcta tttatgatga ttgtgaagga
     5761 gaaaagagag ctaaaaaaga attgaatgaa aaaggattgt ctaaattagt tggtacggtt
     5821 gcaattgtta cgatagcaag ttgtggcgcc gataatattg gtttatttgt tccgtatttt
     5881 gtgacattaa gtgttactaa tttattactt actctgtttg tctttttaat tttaattttc
     5941 ttcttggtgt ttactgcaca aaaattagct aatatcccag gaattggaga aattgttgag
     6001 aaatttagtc gttggattat ggctatcatt tatatagctt taggtttatt tattattatt
     6061 gaaaatgaca ctattcaaac aattttagga tttatatttt aatttagggt gtgattttat
     6121 atgagttatg aaaatacttg tgatgtgatc tgtgtacatg aggataaagt taacaatgct
     6181 ttaagttttt tagaagatga taaatctaag aaattactta acattttaga aaaaatttgt
     6241 gatgagaaga aattgaaaat catattatct ttgattaaag aagatgagtt gtgtgtttgt
     6301 gatatttctt tgatattgaa aatgagtgtt gcttcaactt cacatcattt aaggctttta
     6361 tataaaaatg aggtacttga tttttataaa gatggaaaga tggcatatta ttttattaaa
     6421 gacgatgaaa taagagagtt tttctctaaa aatcaggagg gtttttgaaa cgagtttctt
     6481 cttgtcttga tactataaaa aacaaagtta tataacataa gacgacttat cggaagttat
     6541 ctatcatcgt atattcggag atgatataat atacaggtcg cctatctctc aggcgtcaat
     6601 tcagacgcag agaggaggtg cattactttg ctaatcattt tcgttcacat catagcacca
     6661 gtcatcagtg gctgtgctgt tgcgtattat acttattggc ttagtaaacg caacaaataa
     6721 ttaataggcg actttataag ccagcatcga aaaaatcccc acactattgc agtagtgtgg
     6781 ggattggtgc attaattgtt aatcattttc gttatctaga ttataacact ggttagtaga
     6841 ggaatgcaaa aagataatat tttaagtagt ctttttggat attatcatat gatatattta
     6901 tgtaaattga ttttttatta aaggagcata tatgagtaat actaaaatta aatatcaaat
     6961 ttttatttca tcaacttatt tagatttaat agaagagcgt caagcagtag tagaagcagt
     7021 tttaaacagt aataatattc cagcaggtat ggaacttttt aactcaagta gtaaaagcca
     7081 atgggaaata ataacacaat ggatcaatga atcagatgca gtgatattat tgttaggttc
     7141 tagttatgga acaattgata gtgaagaaaa tattagctat acagaaatgg agtacaattt
     7201 tgctaaatct ttaggtaaac ctatatatgt ttttgagatg aataaagcat ctaccgaatc
     7261 cgcggaaaag tctaaaaaat tagatgagtt taagacaaaa gttaaagaaa atagactaat
     7321 tagtccaaat attaatgata tttcggaatt aaaaagtaaa gtatctcaga ctttaatgca
     7381 aagtgtacct agtgaaatta aagaaaatag tggatggata agagtacagg attgtggtaa
     7441 aaatgtaaaa aaattaaaaa aattggatgc tatacaaaga gatttagata catatgattt
     7501 tttgaaagaa gaactttata aaatattcat gtatgtaaaa actttttatt tccagcacac
     7561 accatttgat gatagttata ttgaagatat agaaaactac ctgctaaatt atgaaaataa
     7621 tccacataaa tcattcatga aaataaaagt ttatgattat aaaaactttt taaaacattt
     7681 aaaaaacata ttgattttaa ttaaacaagg aaaaaagcca ttagctcaag ccggtcattt
     7741 taaattaagc ttttacgaag aggatttaaa attgttacaa aaaaattata agactacgct
     7801 agtcgatatt aaaggattga ataaacattt ttataaggaa tgtgataggt gcttaaaagc
     7861 atataatatt tttattgagg gtataaataa acatttatat gaatgatata agtacaccct
     7921 aatcatacat atataattgt tgtcacttta ctcgatatat gagaatgact ttacctaata
     7981 aatgagaaaa gcaacgcact atattaaaat gcgttgcttt ttctattatc gaatacctat
     8041 aactaaacta tctctagctg tttctacaac ttctgtactt attttatcta aaccatttat
     8101 atccataatt ctgtctatct gcgcaaataa acgatgaatc agcctaaaat tcccttttgt
     8161 aattttaata atcgtcgtta ttgcctcata atcagtaaag tcttcgagtt ttaaatcaaa
     8221 tcctaagtct tgccacttat attctaatat atgatgcgtc tcatctttac ttagattatc
     8281 aaattcatgc gcaaaaccta tacgcgaata tagttgagga taacgagata gttttttctc
     8341 tatacccggc ataccaataa atatcattgc taaattatgt tcatcataaa tagctcttaa
     8401 ttgctctaaa tgttgcactt taaggcgatc aatctcatct actataatta aatcaatata
     8461 tttaaacata tcactataat gtttactatg ttcatgtcca tacttattta caacatgtaa
     8521 tttttgaccc aaatcaatga ttgcagtaat actatataaa tcattcctta atttagtttg
     8581 tttttctgct ggtgcattat aaaatatttt atccaccgat agtatgtcat cggtcgtttt
     8641 actagctaaa tcttcccaac ctctatggtt aacttgtttt tcaatagtat cccaatttgt
     8701 gtaataccta gacgataaag tttttccgac accaggttga ccataacata taccaatata
     8761 ctgatattta atacaagcat cacaaaattc agcaaagcgt ttatactctt tcgtttcaat
     8821 gaaattttga tttttagtca ttacgatatc tctttaattt tttgacgttt ttagtcgttt
     8881 cttgaggtga ataaccacaa tttttttctt ccttaattaa ttccgtggta cttggactag
     8941 caatattttg ttttaagtgt tttcttctct gactacgagc gtgctgtatg tcttttatat
     9001 ctatggagta atcagctatt tctggacata tagcagtaca aagaaattca tctctataaa
     9061 acacacgtat ttcagccata tcatttgggt tataacgaat cagtacatat tcacctacat
     9121 aagcttctag attagtatta ctgtatcgaa aaccttgaaa atgaatgcca tctgaatgaa
     9181 cttttctaga tttaggtatt tccaacaata ataaatcaag ttgttctaag ctacttggca
     9241 tattagggaa aaagtgatta ctattccaat gactgatagg cgtggtatga atagtactat
     9301 gttctttttg attataatct tcaattaaaa agtaacgtaa tttttcttca aaattgtgaa
     9361 aatttattag attactagga gtatcattat tgtttatata tccaggcagt tgttctaaga
     9421 aagtttgatt aactgtctga aagaatcgtt ctatttttcc acgaccacga ggaacaccaa
     9481 ctttcgaaaa catcaagtta attttcaaat caatagcgac ttgttccata tgatgtgaag
     9541 taaagtcact tccatgatct gtgtagaatt tttcgggtat accacacact ggccaattgg
     9601 tatcattttt attccatatt gcttggtgta gtgttaatgc tgtgttttga gcattggggg
     9661 gcatcaaaac ttaagaaata gcctgcaatt gcacgactat agtcatccat aataatagtt
     9721 agccatggtc tattgatatt acctttttgg tctaatataa agatatctag caaagtatgg
     9781 tctgcttgcc atatttcatt gggtctcgag gattctctaa tttgtattaa atcgtactta
     9841 ttttgatagt atttttcacc ctgatgagag aaatcaataa cagacttagg catcgcttta
     9901 ataacactat aaatttgttt ataacttggt atatcaaaat tattttcttt acagtaatta
     9961 gtgattttcc tatgaattgt ggctatacta tttcttttat tcataagcgc aaggcgttca
    10021 atttcatcaa ttatctttgg ttctatttta cgtgttcctt tatcagctct tgtcgcatag
    10081 attagtcctt taagtccttg ttctttatat gacttattcc acctataaag ggtgcttaac
    10141 gcaatccctt tacttttaga aatacttgat aaagattgtt cgcctaggat aaaaggtttt
    10201 ataatattgt acttttgagt agctttttta cgtttggctt cagaaaaatt agttagatac
    10261 ttctccttgt ttttcatctt ccttgtcctc caatttattg aggtaacgat aaattgttgt
    10321 acgtgaaaca tgccactgtt ctgcaattgt cttaattggc gtgccattat cataaagggt
    10381 cttaagtaag tttaaatctt tttgatttaa tttttctggt ctgcctccat atcggcctct
    10441 agcacgtgct gcaattcggc cagctgaaga acgctctaaa attaaattac gttcaaattc
    10501 tgcaaatgct gcgaataaat gaaataataa ttgtccagtt gaacttgatt tatccattgt
    10561 tatattttct tctaaactat ggaaacttac acctcgttcg ttaagctcat taactaatgt
    10621 gattaaatcc tccatattac gtcccaatct atctaatctc caaacaacaa tcgtatctcc
    10681 tgacctcgca aattcaattg ctttatctaa accaggtctt ttactttttg aaccactcat
    10741 atggtcatta aatatctttt cacaaccata tgtatttaat cgatcctcct gtaaatttaa
    10801 attttgtaat ccagttgaaa ctcttgcata acctattttc aaaatacaaa cctcctatat
    10861 acatcttcag tgtaccataa cttaattaca aggtctttta tgaacataga ttttttgttg
    10921 ggtttttgaa cacataatcc tatgtaattc ttacttattt agacataaaa gaagagtgta
    10981 cagaaaatgg ttattttctg tacactctca tctttaataa tatattttaa atgtcattaa
    11041 caaaactaat ttaataagag tcaagcatag tttacatatg tattatgttt gaaacatacc
    11101 tctaattact ttttactaat atcatttaaa atatctcgca attcttcaat ttctttgtta
    11161 tttaattctt catttttcgc aaaattcaac actaaacttt tcatatcccc tccatacagt
    11221 ttattaagaa aggttttagc agttttcatt ttaatatcgt cttctttaat atttgatgag
    11281 taaaaataaa tattttctga tttgtatcgt tttataatct cttttttata tagtcttgtg
    11341 attaatgttc taatcgtttt atcactaact tctttatatt tttgaatttc aactacaatt
    11401 tcattagctg atactgattt tttatcccat attatattca taacatccca ttcagccata
    11461 gatatttcaa cttgcttatt ggccatttaa aacacccatt ccttttaata ttttttcact
    11521 tattaattca gcatttttcc cagacgggtt tccatctgat aaatgtgtag caaaataata
    11581 cttatcatga tttgtaatta cgtaacctac aaaccaccca ttattatact tcccgtttac
    11641 tatacctgta cctgttttcc catacagttc atacttttca tttttcttaa tcaataatga
    11701 agaagataat tgattctttg cttttttact aaaatggtta ttttgttcca tcatattttt
    11761 aaaaactatt acttgttcaa gattagatat tttcaaacta tcttccatcc aatagctttt
    11821 ataacttccc aaattttcat taccataatt taattgcttg agttgagccg cagtatagtt
    11881 ctttggtatt tgattactaa tacgttcgaa gtaccaatta actgaatttt gcattgctgt
    11941 atttaaatct tgttccttat tccaagactc gaaaagataa tgtttatgat tccatgacat
    12001 acgtgaattt ttatcactta taatatgacg gtcaagtcca aacagtgcta aataaatttt
    12061 gtaagttgaa tcaggagaat atctttttct actttctttt tcattataaa tatagtattt
    12121 gtctttcttc atgctgtaca taacgaaaga tccactattt gaaccaaaat ttttactttc
    12181 atctaaaatt tggtaatcgc tttgtaaggg ctttttataa ttataatcag ttaaggattg
    12241 ccccattaaa aactggcttt gaattatcat gataaaaaaa gtaaaaatac aaataaaaat
    12301 tagaattaat tttgactgct ttttcagatc ggcttctttt atattaatta atctattttt
    12361 gagtaatgat tttttaccat taaatgaatg gcttaatata tttttgttga aaaatgaggt
    12421 ttttaatacg gagtccataa tagattccgc ataagtttta aattcatttt tgttaatatt
    12481 attaaggaca aatctatcgg cttctacttc attgtcatga attatctttc tttttacaat
    12541 atgtactaat ggattgtaac tcataataat agagaagata ttaaagataa ttaaatgtaa
    12601 agtatctcta tttttagcat gagcatattc atgcagtatt atatatttta gtcttttatc
    12661 aattacactt ttaaaatatg aactaggaat caaaataata tatttcccat accaaaaagt
    12721 tattggagat tgaatagcct ctgcttttcg aatcacaata tttttttnat attgatggtt
    12781 gaaaagtatc gtatctattt tatttttttc attttcgttt agataaagtg actgtttctt
    12841 taaatattta agatataata aggctttcaa aaatttaaaa cttaaaataa taactaaaac
    12901 tatccaaata actgtgcaga tattatcaat tgaatcccaa ttaaacttat ggatatctgt
    12961 tgcgaactct tgaacaggtt tggtggtaat tatgttatgg ttcaagtcgt gtgacttact
    13021 ttcaactgtg ggcgcttgat tattcacatt attaaatttt ataaaagaga atttaattgg
    13081 gataaaagga attaatccag caagcacagt tagataccaa actttataat ttaaactata
    13141 attaaaatag cgttttaata tgtacctaaa aaatactaac aatagaaata taaaacaaaa
    13201 gcttactaca ctcattatta gtaatttagc cattttgaca ccttctttca aatatttata
    13261 ataaacaatt gacatcaata ttacaattgt aatattattg ttttgtaaaa attacaactg
    13321 taatatcgga gggtttattt tgaaaaagtt aatattttta attgtaatgg ctttagtttt
    13381 aagtgcatgt aattcaaaca gttcacatgc caaagagtta aatgatttag aaaaaaaata
    13441 taatgctcat attggtgttt atgctttaga tactaaaagt ggtaaggaag taaaatttaa
    13501 ttcagataag agatttgcct atgcttcgac ttcaaaagcg ataaatagtg ctattttgtt
    13561 agaacaagta ccttataata agttaaataa aaaagtacat attaacaaag atgatatagt
    13621 tgcttattct cctattttag aaaaatatgt aggaaaagac atcactttaa aagaacttat
    13681 tgaggcttca atgacatata gtgataatac agcaaacaat aaaattataa aagaaatcgg
    13741 tggaatcaaa aaagttaaac aacgtctaaa agaactagga gataaagtaa caaatccagt
    13801 tagatatgag atagaattaa attactattc gccaaagagc aaaaaagata cttcaacgcc
    13861 tgctgctttc ggcaagactt taaataaact tatcgcaaat ggaaaattaa gcaaaaaaaa
    13921 taaaaatttc ttacttgatt taatgtttaa taataaaaac ggagacactt taattaaaga
    13981 tggtgttcca aaagactata aggttgctga taaaagtggt caagcaataa catatgcttc
    14041 tagaaatgat gttgcttttg tttatcctaa gggccaatct gaacctattg ttttagtcat
    14101 ttttacgaat aaagacaata aaagtgataa gccaaatgat aagttgataa gtgaaaccgc
    14161 caagagtgta atgaaggaat tttaatattc taaatgcata ataaatactg ataacatctt
    14221 atagtttgta ttatattttc tattatcgtt gacatgtata attttgatat caaaacctga
    14281 ttttcccttt attattttcg agatttattt tcttaattct ctttaacaaa ctagaaatat
    14341 tgtatataca aaaaatcata aataatagat gaatagttta attataggtg ttcatcaatc
    14401 gaaaaagcaa cgtatcttat ttaaagtgcg ttgctttttt ctcatttata aggttaaata
    14461 attctcatat atcaagcaaa gtgacataat tgttgaattt atagtaactg aaacgtatga
    14521 ttagggtgta tattaattat gagatggaaa tcaatgattg ttggctatgc gagagtatca
    14581 tcgaacgatc aaaatttaga aagacaactt gaaaatttaa agacgttttg tgctgaaaaa
    14641 atatttacag aaaaacagtc tgggaaatct attgaaaata gaccagtact tcaagaagca
    14701 cttaactttt tgaggatggg agatcggttt gtagtagaat ccattgattg tttaggtcgt
    14761 aattatgatg aagtgattca taccgttaat tatttaaaag acaaagaagt acaattaatg
    14821 attactagct tacctatgat gaatgaagtg gttggcaatc cattactgga taagtttatg
    14881 aaagatttaa ttattcaaat attagcaatg gtttcagaac aagagagaaa tgaaagtaaa
    14941 cgtcgacaag cgcaaggaat tcaagttgcg aaggaaaaag gcgtatataa agggcgcccc
    15001 ttactttatt caccaaatgc taaagatcca cagaaacgta ttatttatca tcgcgttgta
    15061 gaaatgttag aagaaggcca atcaattagt aaaattgcga aagaagtaaa tataacaagg
    15121 cagacgattt acagaattaa aaacgataat gatttgattt aataaacttt gtttcaatgc
    15181 aactgagagc ttctcacagc gtctcaaaac agatgattat aatctattat gagtttttaa
    15241 taataagaca agaaaagaga gcgtaaatat gctctctctt tttctcatta acgaatgttt
    15301 ataacgcaat catgatgaga gtattaatac agttaattat ttgaaatact ttagtttata
    15361 taatgttgaa ttataggtag tgaaattgta tttattatac attgtcatat cgttgtttaa
    15421 tgatagttaa tttaaggata atagaattaa tattatatat agatgaacaa aacaagcaac
    15481 agagcagaaa aaacactttt agattatttt tactcattct ctattttatt tatttttgct
    15541 ataataaata aagaatatta aatggaggtg tttttatgaa aaagaaattt gtttctagtt
    15601 gtattgctag tacaatctta ttcggcactt tattaggtgt aacttataaa gctgaagctg
    15661 caacagtaca tgtagctggt ggtgtttgga gccatggtat tggaaaacat tacgtatggt
    15721 cttattatag tcacaataaa agaaatcatg gttcaacagc agtagggaaa tattcatctt
    15781 ttagtggtgt tgctcgacct ggtgttcaat ctaaggcatc tgctccaaag gcttggggtg
    15841 gaaacaaaac attttatagt cttcactaat tacatatatt aattaaggag aatagacaga
    15901 attaagtaaa cttaattctg tctattctct tgaaagaggc aatatgaaaa aattcaaatt
    15961 atttttagat tttagtactt tattattaat ttcagggcta ttatttttat ttttcttcaa
    16021 agaaaatgaa gaaattatac ctgaaagttc caatatttta acaatctcta attgggataa
    16081 atctaacagt aaatcaaaag tgttagatgt cattgaatca ggcgccaaaa atcaaaatat
    16141 acaaataatt aaatccgtta aagattttga taataaaaaa gaattttttg ttttcaactc
    16201 aaaacgaaat aattctgact ttatacgtaa taaaacatca cttttaactc catcagattt
    16261 attaaacaga gagataaaag gaaagtatta tattattggt gaacatttca atgtagaaga
    16321 gcttacgagt gaattaaaaa aagctggttt aacatctgaa gttgaataca taaatagaaa
    16381 catattattt tttgaattag tcatagataa tgatttatta gtgcctttca tattcttagg
    16441 cgtattatat cttttgtact tcttatatga cagaggatat aatttgaaat tttatgctat
    16501 tcaaaagcta catggctttt caactacacg cattattttt cataatattc atataaaaat
    16561 catttattgg ctagtactta ccgctatttt ctttattgct aatatattaa tcattcatat
    16621 agccaattta gaattggatt tcttaatgtt tattcgtaga tttatcgtgt tgctttttgt
    16681 ttttgcttgt attactacat tgctgtggct gatttcgtat agtcttcttt tgaagttaag
    16741 tattccatta atcttaaaag ggaaaaaagg atataagttt tcaatattta tgggtacctt
    16801 caccaaatgt atcatggtgc taatactatc ttttttactg gcacaaaatt taaatgctta
    16861 tacgaagtta aagaatatat atgactctga aaaaatctgg caaaagttag ataattacta
    16921 tacattagag atttctccta atattagaaa ttcagaagaa aaacaaattt tagaaactaa
    16981 tatatacaat ttaattaaga aaagcgaaca acttggtgga ttgcttttaa agaataataa
    17041 tatagccaat cccgataaaa acaattacat tcctgaaaat ggcaatgtct tttttatcaa
    17101 taacaatttt ctgaatttct ataaaaatat aaatcatgat tttaaaatga ttgacaatca
    17161 ttcggataaa ataaacgtgt ttattcctcc aaggttacaa tatcaaaaat ctgaaattca
    17221 aaaaaatcac caaggatgga ttgactttca aaagcaacaa aacaaaaaag tagatgtgca
    17281 agtactgtca aaaaacgtat ctgttttttc ttttgatcgc acaactaatt tgaaatttgg
    17341 gtatctagat tctccaatag taatgttgtt gacacttgac gatttaacag gagattttta
    17401 tttagctgct gtttctcaag gtggatatct atttaaagat ttagatacac ttaaacagtt
    17461 gcttaaagat aatcacctag aagaagaaat tagcggtata actaattaca aggattctgt
    17521 gttaaatgaa ttaaatgaaa cgaaaacaaa aatgataata acaatagtta ctattattat
    17581 taacgttttc attcttttga tagctactgt atttgaaaca attcaatatt ttagctggaa
    17641 taaaaagcaa ctattattaa gaaaaattca tggttattca ttattcagca gtaatgtacg
    17701 ttatttaaca atttctatct tactttctat tatgttagct tacactacgc atattttatt
    17761 tggttcaaag atattactat tcataataat gtctattgct attattcaac atttacttca
    17821 aattgcttat attaaatatc ttgaaaaata ctttaaagat ttaatgaggg agatttaaac
    17881 aatgaaaaga actttaatta ttgtaacaat tgtactatta atcatcatac ttagtctgtt
    17941 attggttaga aatgagcatt tagatcgttt taacccactg ttaaaagaaa aagtatctta
    18001 tgccaaagtt ccaaaagata cccaggacta tagaaatata actgtatact ctaaaaatgg
    18061 agaaaaaaag agttataaat tggatttttt aggttatgat cctacaaaag aatatgtgaa
    18121 agtaaatcat aaagggaaat atgtgcgttc gatagaatac attacaaaag atattcctag
    18181 ctttttaaaa tgaggtgacc gatagtgata aaacttgaaa atgtttttgt aaaaaaaggt
    18241 aataaaaaca ttttagacgg atgtaacttt aattttgaaa aaggaaaatc atatgcttta
    18301 gttggagaaa gtggcgctgg aaaatctact ttacttaaca taatcgctgg gttcgaagat
    18361 gtatcacaag gaagcatata tattgaagat aagttactaa aaaagaaagt cgatttttat
    18421 agatatacgt tagggtattt gtttcaaaat tttgctttac ttgaaaatca aacaatcagt
    18481 caaaatttag atttagccct aaagttcaaa aagaataaaa aagataatat gaacttaaag
    18541 aaagaagtat taaaaaaggt cggcctagat ttagatatca agagaattgt tagttctcta
    18601 agcggtggtg aacaacaaag agtagcattg gcaagattaa tattaaaaga tccgaaaatc
    18661 attttagctg atgaacctac tgggtcacta gatacgaaaa atggaaaaat agttattgat
    18721 ttattattga agctacttga tgaaaataaa actatgattg tcgtaacgca tgatttagag
    18781 cttgcgaaac gatttgatgt catagtcaat atttctgagc ttagaagtta agaaatattg
    18841 ataggtatag ccatacatag agaaaaaaca atatgaaata tgattagtca ttacttttga
    18901 gttttttaat ttaaggactg gattttccag tcctttttta tgatgacaaa aaacaagcct
    18961 cgcagagcac acgtttttaa tgacttattt ggtttttaat aagtctagta tgttaaaact
    19021 tttctgtgtt taggtgttat aatcatatgc agtggaagtt gatttattat gtcttattca
    19081 attattcgag ttgttaaagt gaaatcaaaa acaaatacaa gaggtattca aagacatatt
    19141 caaagagaaa ataaaaatta tgaaaatata gatattgatt taagtaagtc atatttaaac
    19201 tatgatttag tcaatgatac taagtttgat tttaataaaa aaattgatga gaaaatcgaa
    19261 aaaaattata aagggaaacg caaaattaga acagatgcca ttaaacatat tgatggatta
    19321 attacatcag ataatgtgtt ttttaatcaa ttatctgaag aagagacaaa atagtttttt
    19381 aagcatgcta aagcgttctt ggaagaagaa tacggtaaag aaaatctttt atatgcgaca
    19441 gtacatatgg atgagataac accacatatg cattatggcg tagttcctat tactaaagat
    19501 ggacgtttaa gtgcgaaaga agttgtaggt aataaaaaag cattaaccga attccaagat
    19561 agattcaata cgtatattaa taagcaaggc tatgatttaa aacgaggaat ttctagacaa
    19621 cttacaaaag aaaaacatga tcaagttagc cgttataaac aaaaaacaga atatcataaa
    19681 caaatgcata tgcgctagaa gcaaatagag gattatttaa agcaagaaaa tgataaattg
    19741 atacaaaact accaaaaatc attagatacg cttaaaaagc ttctgagtgt catgtatgaa
    19801 attaaaacta aaaatgtagg tggatggttt cataaagaga agcaagaaac aggcaatatt
    19861 gtaattacta aaactgattt tgaaaaatac actaaacaaa ttaaagcagc acagatgata
    19921 ttagatgatt atgaatgtat taaaagtggg aagtcattaa aaaaagcaga gaaacaaaat
    19981 gaaagtttag ttaatgaatt gactagtgtc catatggaaa atgaaaagct ggttgaagaa
    20041 tttaatgatt tagcacaacg ttataattat ttgttgtcag agaatgaaaa gaaagataaa
    20101 gaactaaatt atacgcttaa gttattcaat caagttttta aaatcattaa aagtatgatg
    20161 aaagaagagc gttatcatac actaataaat catattgata atcatttaga caattctaaa
    20221 atacgtgaag taatgacgat agataacaat gatgaacagt tctttaagaa gaaatatcaa
    20281 gcacaagaac gagaaatcat ttttaaagaa gatagagaag atggttatac attataaaaa
    20341 tagatattta aatgcatttg tttgaggtta attatttttt aggatgaaaa ataggtagcc
    20401 cccctcgaac tttttaatat atttttataa atctttttaa aaaccttttt aggggcttgt
    20461 tcagccctag agcaacaagg gatttcaatg cctaaaggag tgtttttgcc acataaaagg
    20521 agtgtttttg ccacataaaa ggagtgtttt tgccacataa aaggagtgtt tttgccacat
    20581 aaaaggagtg ttttaaaaag ttgtactcct tttatggttt gacattgata ataaagtagt
    20641 ttattgtgaa taaaagtttt caaatgggag tgtatattca aacgatactc ctttaggttc
    20701 gtaataaagg gggctgtatc
//
