LOCUS       NZ_CP012971            20633 bp    DNA     circular CON 21-NOV-2023
DEFINITION  Staphylococcus aureus strain ST20130939 plasmid pST20130939,
            complete sequence.
ACCESSION   NZ_CP012971
VERSION     NZ_CP012971.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN04166389
            Assembly: GCF_001611425.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 20633)
  AUTHORS   Trouillet-Assant,S., Lelievre,L., Martins-Simoes,P., Gonzaga,L.,
            Tasse,J., Valour,F., Rasigade,J.P., Vandenesch,F., Muniz
            Guedes,R.L., Ribeiro de Vasconcelos,A.T., Caillon,J., Lustig,S.,
            Ferry,T., Jacqueline,C., Loss de Morais,G. and Laurent,F.
  TITLE     Adaptive processes of Staphylococcus aureus isolates during the
            progression from acute to chronic bone and joint infections in
            patients
  JOURNAL   Cell Microbiol 18 (10), 1405-1414 (2016)
   PUBMED   26918656
REFERENCE   2  (bases 1 to 20633)
  AUTHORS   Trouillet-Assant,S., Lelievre,L., Martins-Simoes,P., Almeida,L.G.P.,
            Tasse,J., Valour,F., Rasigade,J.-P., Guedes,R.L.M.,
            Vasconcelos,A.T.R., Cailon,J., Lustig,S., Ferry,T., Jaqueline,C., de
            Morais,G.L. and Laurent,F.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-OCT-2015) Labinfo, LNCC - Laboratorio Nacional de
            Computacao Cientifica, Rua Getulio Vargas 333, Petropolis, RJ
            25651070, Brazil
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.9
            Genome Coverage                   :: 66x
            Sequencing Technology             :: 454
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/21/2023 11:08:33
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,722
            CDSs (total)                      :: 2,640
            Genes (coding)                    :: 2,570
            CDSs (with protein)               :: 2,570
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 36 of 70
            Pseudo Genes (incomplete)         :: 31 of 70
            Pseudo Genes (internal stop)      :: 21 of 70
            Pseudo Genes (multiple problems)  :: 17 of 70
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP012971.1.
            Bacteria available at the French National Reference Center for
            staphylococci (CNR Staphylocoques) in Lyon, France.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..20633
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="ST20130939"
                     /isolation_source="26-year old man with an implant
                     associated osteitis"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="pST20130939"
                     /geo_loc_name="France"
                     /collection_date="2009-08"
     gene            1..861
                     /locus_tag="SAST39_RS13710"
                     /old_locus_tag="SAST39_02813"
     CDS             1..861
                     /locus_tag="SAST39_RS13710"
                     /old_locus_tag="SAST39_02813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000145511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_000145511.1"
                     /translation="MTGETVVYKNEMNLVPLRRFTATEINLFFAMCNKLKEQDTNTLRL
                     SFDELKKLSNYSPETRNINRFANDLDNVYKKMLNLTIRYEDDDVIERFVLFNHYRIHKR
                     EQYLEISTSSNLKHILNSITNNFTKFELKEMTRLKSTYSKNMFRLLKQYKHTGYLKIHI
                     DDFKNRLDIPKSYRMTDINKNVFKPIIIELGSIFNNLTINKIKAKKGRKIEWIEFTFDA
                     EKRIHNKRQPQMSKIDKSRQYVRREKTPKWLEERSYEKQPQKDYDPQLEKEREDFLKQL
                     ELNWE"
                     /name="replication initiation protein"
     gene            948..1289
                     /locus_tag="SAST39_RS13715"
                     /old_locus_tag="SAST39_02814"
     CDS             948..1289
                     /locus_tag="SAST39_RS13715"
                     /old_locus_tag="SAST39_02814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761340.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000761341.1"
                     /translation="MKLAEAIKEQRELKGWSQEELANILKVSRQSVSKWESAKNYPSLD
                     ILIAMSDLFGISLEHLIKGDARFKKVILEGNYRESNRVPSIVDFLYDFWWLFFPVAGFL
                     VWAIHSFMG"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(1528..1599)
                     /locus_tag="SAST39_RS14580"
                     /old_locus_tag="SAST39_02816"
     CDS             complement(1528..1599)
                     /locus_tag="SAST39_RS14580"
                     /old_locus_tag="SAST39_02816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_106873653.1"
                     /translation="MNEILVHIMTTAISGCLVTLFGY"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            1748..1933
                     /locus_tag="SAST39_RS13720"
                     /old_locus_tag="SAST39_02817"
     CDS             1748..1933
                     /locus_tag="SAST39_RS13720"
                     /old_locus_tag="SAST39_02817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000466619.1"
                     /translation="MFGDQRQEATKYVIKEGYQDIYFLNKNGEWYYFEVRSVWRGKHII
                     RVKDGLLGWRKEIVTE"
                     /name="hypothetical protein"
     gene            complement(2152..2895)
                     /locus_tag="SAST39_RS13725"
                     /old_locus_tag="SAST39_02818"
     CDS             complement(2152..2895)
                     /locus_tag="SAST39_RS13725"
                     /old_locus_tag="SAST39_02818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843758.1"
                     /translation="MKSVKRLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESATEDKQKKESDNINFESKSDAQIVEILKNQINTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNAR
                     QNVDAQEKTYTTSPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAQREDVSANPND
                     NDSDIEEKSEETEPKKGFWSRLFGN"
                     /name="DUF536 domain-containing protein"
     gene            3306..3982
                     /locus_tag="SAST39_RS14640"
                     /pseudo=""
     CDS             3306..3982
                     /locus_tag="SAST39_RS14640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /name="replication initiator protein A"
     gene            <3993..4275
                     /locus_tag="SAST39_RS14730"
                     /pseudo=""
     CDS             <3993..4275
                     /locus_tag="SAST39_RS14730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199895.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            5485..6102
                     /gene="cadD"
                     /locus_tag="SAST39_RS13740"
                     /old_locus_tag="SAST39_02794"
     ARG             5486..6099
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="99.51"
                     /coverage="100.0"
     gene            6121..6468
                     /locus_tag="SAST39_RS13745"
                     /old_locus_tag="SAST39_03581"
     CDS             6121..6468
                     /locus_tag="SAST39_RS13745"
                     /old_locus_tag="SAST39_03581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119691.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNQEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            6637..6729
                     /locus_tag="SAST39_RS14590"
     CDS             6637..6729
                     /locus_tag="SAST39_RS14590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            6941..7819
                     /locus_tag="SAST39_RS13750"
                     /old_locus_tag="SAST39_02796"
     CDS             6941..7819
                     /locus_tag="SAST39_RS13750"
                     /old_locus_tag="SAST39_02796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="WP_062911948.1"
                     /translation="MSNTKIKYQIFISSTYLDLIEERQAVVEAVLNSNNIPAGMELFNS
                     SSKSQWEIITQWINESDAVILLLGSSYGTIDSEENISYTEMEYNFAKSLGKPIYVFEMN
                     KASTESAEKSKKLDEFKTKVKENSGWIRVQDCGKNVKKLKKLDAIQRDLDTYDFLKEEL
                     YKIFMYVKTFYFQHTPFDDSYIEDIENYLLNYENNPHKSFMKIKVYDYKNFLKHLKNIL
                     ILIKQGKKPLAQAGHFKLSFYEEDLKLLQKNYKTTLVDIKGLNKHFYKECDRCLKAYNI
                     FIEGINKHLYE"
                     /name="DUF4062 domain-containing protein"
     gene            complement(7939..8754)
                     /locus_tag="SAST39_RS13755"
                     /old_locus_tag="SAST39_02797"
     CDS             complement(7939..8754)
                     /locus_tag="SAST39_RS13755"
                     /old_locus_tag="SAST39_02797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019467708.1"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_000164958.1"
                     /translation="MTKNQNFIETKEYKRFAEFCDACIKYQYIGICYGQPGVGKTLSSR
                     YYTNWDTIEKQVNHRGWEDLASKTTDDILSVDKIFYNAPAEKQTKLRNDLYSITAIIDL
                     GQKLHVVNKYGHEHSKHYSDMFKYIDLIIVDEIDRLKVQHLEQLRAIYDEHNLAMIFIG
                     MPGIEKKLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWQDLGFDLKLEDFTDYEAIT
                     TIIKITKGNFRLIHRLFAQIDRIMDINGLDKISTEVVETARDSLVIGIR"
                     /name="AAA family ATPase"
     gene            complement(8747..10190)
                     /locus_tag="SAST39_RS13760"
                     /pseudo=""
     CDS             complement(8747..10190)
                     /locus_tag="SAST39_RS13760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790716.1"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /name="DDE-type integrase/transposase/recombinase"
     gene            complement(10162..10755)
                     /locus_tag="SAST39_RS13765"
                     /old_locus_tag="SAST39_02800"
     CDS             complement(10162..10755)
                     /locus_tag="SAST39_RS13765"
                     /old_locus_tag="SAST39_02800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690636.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690638.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNQKDLNLLKTLYDNGTPI
                     KTIAEQWHVSRTTIYRYLNKLEDKEDEKQGEVSN"
                     /name="recombinase family protein"
     gene            complement(11019..11399)
                     /gene="blaI"
                     /locus_tag="SAST39_RS13770"
                     /old_locus_tag="SAST39_03583"
     ARG             complement(11023..11399)
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="99.21"
                     /coverage="100.0"
     gene            complement(11389..13146)
                     /gene="blaR1"
                     /locus_tag="SAST39_RS13775"
                     /old_locus_tag="SAST39_04567"
                     /pseudo=""
     CDS             complement(11389..13146)
                     /gene="blaR1"
                     /locus_tag="SAST39_RS13775"
                     /old_locus_tag="SAST39_04567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096376.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactam sensor/signal transducer BlaR1"
                     /name="blaR1"
     gene            13253..14098
                     /gene="blaZ"
                     /locus_tag="SAST39_RS13780"
                     /old_locus_tag="SAST39_02804"
     ARG             13254..14095
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            14467..15075
                     /locus_tag="SAST39_RS13785"
                     /old_locus_tag="SAST39_02805"
     CDS             14467..15075
                     /locus_tag="SAST39_RS13785"
                     /old_locus_tag="SAST39_02805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002436987.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001566953.1"
                     /translation="MIVGYARVSSNDQNLERQLENLKTFCAEKIFTEKQSGKSIENRPV
                     LQEALNFLRMGDRFVVESIDCLGRNYDEVIHTVNYLKDKEVQLMITSLPMMNEVVGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRI
                     IYHRVVEMLEEGQSISKIAKEVNITRQTIYRIKNDNDLI"
                     /name="recombinase family protein"
     gene            15489..15782
                     /locus_tag="SAST39_RS13790"
                     /old_locus_tag="SAST39_02806"
     CDS             15489..15782
                     /locus_tag="SAST39_RS13790"
                     /old_locus_tag="SAST39_02806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="WP_000726502.1"
                     /translation="MKKKFVSSCIASTILFGTLLGVTYKAEAATVHVAGGVWSHGIGKH
                     YVWSYYSHNKRNHGSTAVGKYSSFSGVARPGVQSKASAPKAWGGNKTFYSLH"
                     /name="lactococcin 972 family bacteriocin"
     gene            15857..17791
                     /locus_tag="SAST39_RS13795"
                     /old_locus_tag="SAST39_02807"
     CDS             15857..17791
                     /locus_tag="SAST39_RS13795"
                     /old_locus_tag="SAST39_02807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001670421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="WP_000713729.1"
                     /translation="MKKFKLFLDFSTLLLISGLLFLFFFKENEEIIPESSNILTISNWD
                     KSNSKSKVLDVIESGAKNQNIQIIKSVKDFDNKKEFFVFNSKRNNSDFIRNKTSLLTPS
                     DLLNREIKGKYYIIGEHFNVEELTSELKKAGLTSEVEYINRNILFFELVIDNDLLVPFI
                     FLGVLYLLYFLYDRGYNLKFYAIQKLHGFSTTRIIFHNIHIKIIYWLVLTAIFFIANIL
                     IIHIANLELDFLMFIRRFIVLLFVFACITTLLWLISYSLLLKLSIPLILKGKKGYKFSI
                     FMGTFTKCIMVLILSFLLAQNLNAYTKLKNIYDSEKIWQKLDNYYTLEISPNIRNSEEK
                     QILETNIYNLIKKSEQLGGLLLKNNNIANPDKNNYIPENGNVFFINNNFLNFYKNINHD
                     FKMIDNHSDKINVFIPPRLQYQKSEIQKNHQGWIDFQKQQNKKVDVQVLSKNVSVFSFD
                     RTTNLKFGYLDSPIVMLLTLDDLTGDFYLAAVSQGGYLFKDLDTLKQLLKDNHLEEEIS
                     GITNYKDSVLNELNETKTKMIITIVTIIINVFILLIATVFETIQYFSWNKKQLLLRKIH
                     GYSLFSSNVRYLTISILLSIMLAYTTHILFGSKILLFIIMSIAIIQHLLQIAYIKYLEK
                     YFKDLMREI"
                     /name="bacteriocin-associated integral membrane family
                     protein"
     gene            17795..18106
                     /locus_tag="SAST39_RS13800"
                     /old_locus_tag="SAST39_02917"
     CDS             17795..18106
                     /locus_tag="SAST39_RS13800"
                     /old_locus_tag="SAST39_02917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="WP_000831610.1"
                     /translation="MKRTLIIVTIVLLIIILSLLLVRNEHLDRFNPLLKEKVSYAKVPK
                     DTQDYRNITVYSKNGEKKSYKLDFLGYDPTKEYVKVNHKGKYVRSIEYITKDIPSFLK"
                     /name="YxeA family protein"
     gene            18118..18744
                     /locus_tag="SAST39_RS13805"
                     /old_locus_tag="SAST39_02809"
     CDS             18118..18744
                     /locus_tag="SAST39_RS13805"
                     /old_locus_tag="SAST39_02809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000593103.1"
                     /translation="MIKLENVFVKKGNKNILDGCNFNFEKGKSYALVGESGAGKSTLLN
                     IIAGFEDVSQGSIYIEDKLLKKKVDFYRYTLGYLFQNFALLENQTISQNLDLALKFKKN
                     KKDNMNLKKEVLKKVGLDLDIKRIVSSLSGGEQQRVALARLILKDPKIILADEPTGSLD
                     TKNGKIVIDLLLKLLDENKTMIVVTHDLELAKRFDVIVNISELRS"
                     /name="ABC transporter ATP-binding protein"
     gene            18982..19611
                     /gene="mobV"
                     /locus_tag="SAST39_RS14735"
                     /pseudo=""
     CDS             18982..19611
                     /gene="mobV"
                     /locus_tag="SAST39_RS14735"
                     /inference="COORDINATES: protein motif:HMM:NF013258.3"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /name="mobV"
     gene            19705..20250
                     /locus_tag="SAST39_RS13820"
                     /old_locus_tag="SAST39_04570"
     CDS             19705..20250
                     /locus_tag="SAST39_RS13820"
                     /old_locus_tag="SAST39_04570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001805533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000273005.1"
                     /translation="MYEIKTKNVGGWFHKEKQETGNIVITKTDFEKYTKQIKAAQMILD
                     DYECIKSGKSLKKAEKQNESLVNELTSVHMENEKLVEEFNDLAQRYNYLLSENEKKDKE
                     LNYTLKLFNQVFKIIKSMMKEERYHTLINHIDNHLDNSKIREVMTIDNNDEQFFKKKYQ
                     AQEREIIFKEDREDGYTL"
                     /name="hypothetical protein"
     ARG             13254..14098
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     BGC             10489..20633
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          4333..4480
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="81.333"
                     /coverage="100.0"
                     /evalue="2.96e-25"
     Typing          2..861
                     /name="rep_cluster_2214"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(2153..2895)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.866"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          18983..19257
                     /name="MOBV"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="94.565"
                     /coverage="100.0"
                     /evalue="4.71e-46"
ORIGIN
        1 atgacaggag agacagttgt atataaaaat gaaatgaatt tagttccatt aaggcgattt
       61 acagctactg aaattaattt attttttgcg atgtgtaata aattaaaaga gcaagatact
      121 aatacattac gtttgtcttt tgatgaatta aaaaaattaa gtaattatag tccagaaaca
      181 cgtaatatta atagatttgc taatgattta gataatgtgt ataaaaagat gttgaattta
      241 accattagat atgaagatga tgatgtaata gaaagattcg ttttattcaa tcattataga
      301 atccataagc gagaacaata tctagaaata tcaacttctt caaatttaaa acacatattg
      361 aattcaatta ctaataattt tacaaaattt gaattaaaag aaatgactag gcttaaatct
      421 acatattcta aaaatatgtt tagattactt aaacaataca aacatacagg ctatttaaaa
      481 attcacatcg atgattttaa aaatcgttta gatataccta aatcttatcg tatgactgat
      541 attaacaaaa atgtttttaa acctattatt attgaattag gttctatatt taataatctt
      601 actatcaata aaatcaaagc gaaaaaaggg cgtaaaattg aatggataga gttcacattt
      661 gacgctgaga aacgcattca taacaaacga caacctcaaa tgtccaagat agataaatca
      721 agacaatatg tgaggcgtga aaagacgcct aaatggttag aagaacggtc atatgaaaag
      781 caacctcaaa aagattacga cccacaatta gagaaagaac gagaggattt tttaaaacaa
      841 cttgaactga attgggaata acgcaacttt tcgttgcgag ttggttaact aaaagtatcg
      901 tgacttttca attattttaa ttatagtttg agttaaggag tgattttatg aaattagctg
      961 aagctataaa agaacagaga gaattaaaag gatggtctca agaggaatta gccaatatat
     1021 taaaggtttc cagacaaagt gtttctaaat gggaaagtgc caaaaactat ccttccttag
     1081 atattttgat tgctatgagc gatttattcg gaatctcttt agagcattta attaaaggag
     1141 atgcacgttt taaaaaagtt attttagagg gaaattatag agagagtaac agggtacctt
     1201 ccatagttga ttttctttat gatttttggt ggcttttctt tcctgttgcc ggatttttag
     1261 tttgggccat tcattcgttc atgggttgat tttaaaatca aaatttaatg cacatcaggc
     1321 aatatgaaaa aggaaagtat ttttacgaca ccttgaaatg tattgataag aatagaagag
     1381 tttacaaaag gcaatatgaa atatatacta aaagtaacaa gaatttcgtt tgtaaacgca
     1441 caaaaccccg aactattcgc cgtagttcgg ggttttttgg tgaattggct ttaatcgtct
     1501 atattatttt ttatcacgtt tatggagcta ataaccaaat aacgtaacga gacaaccact
     1561 gattgccgtt gtcatgatgt gaacaagaat ttcattcata aatcgcacct cctctctacg
     1621 ccgaattgac atctgagaga tagacgacct tcacattata acaaatctct ccttccatga
     1681 aataacatga atattaataa atgttgttat atattaaaga taaataaata taagggtggg
     1741 attgataatg tttggcgatc aaagacaaga agctacaaaa tatgtcatta aagaaggtta
     1801 tcaagatatt tatttcctca acaaaaacgg ggaatggtat tatttcgaag taagaagtgt
     1861 ctggcgtggc aaacatatta ttagagttaa agatggtttg ttaggttgga gaaaagaaat
     1921 agtaactgaa taaagataca aaatacttgc caatgcaaaa gaatgaaaac gcgtcaaatc
     1981 aacgatgtat aaaagatgca taaaagataa tgaaagtaaa aagccataaa tgccgtcata
     2041 taggcattta tggctttttg tttggttaac ataatcgatg attatcagaa gttcaattca
     2101 cataaaaaag cacggctaat ttatgaactt gtcgtacctt tttaattaaa attagttacc
     2161 aaatagacga ctccaaaacc cctttttagg ttccgtttct tcactctttt cttctatatc
     2221 actatcattg tcatttggat tagctgaaac gtcttctctt tgtgcttctt caccttgtgt
     2281 actttcgtcg ctttgacttc cagatatatc cttatattga atctctgttt ctttagtttc
     2341 ttcctgatct cggttaatat ttacaggact agtagtatat gttttttctt gtgcatcaac
     2401 gttttgtcta gcgttagtag atgtatcaaa gggataatta aggtgttttt ctttttctaa
     2461 ttgattttct aatttttgaa tctttttatt actctctaat gccagaactt gctgattctc
     2521 aagcaatttt gatctttctt gcaactcttt tctgtaaaat tcaattgttg tttcatgacg
     2581 actttcttgt ttttcaattt gattatttaa agtattaatc tgatttttaa gtatttctac
     2641 tatttgagca tcgcttttag attcaaaatt aatattatcc gactcttttt tttgtttgtc
     2701 ttcagtagca ctttcaaaac catatttctt tttattttca tttactcttt gaatgatttt
     2761 ttctatatcg gtatcttctt taataaacga agtgttttcc tgttttattg tctctatatt
     2821 caatctctta atattattaa aaatcgtttg cttactaacc cctaattctt cactcaacct
     2881 ttttacactt ttcatatcat caacccttta taaaatgttt ataaaccctt agtaaaatat
     2941 tataagctta taacgattaa taataaagta atcgacaaat aaaaatataa attcgccaac
     3001 ctttttatca agggtttgta aagggtttat ggtgtttatc aaaggtttat aaacctatat
     3061 tttccctttt ttaagtttat tcaaagtgct ataataacct taatataaca aaaaccccaa
     3121 ctactggtaa tagtcggggt ttggtaataa aacgtttaga aactgtttat ttatataatt
     3181 ttcgatactt agattatata atgaataata tcttagtgca agcacctaga ttattaaata
     3241 aacacaaaaa atgtaagcgt tttattacct cttaccaaac taaaattcgg aaagaggttt
     3301 ttattatgtc aattaaactt tacaacataa atgaggaata cagagaaaag ttttatcaaa
     3361 taccgaaagt attttttaca aatcctaaat atatcaagtt atccaatgat gcaaaaatgg
     3421 catggggtat tcttagagat cgtttagatt tatcaattaa aaatggttgg gttgattcta
     3481 aaacaggtaa tatttatttt tattacaaaa atgaaaaccc acaaaatata ttaaattgta
     3541 aaaaagataa agtaattaaa ataaagaaag aacttaattg aagccgaatt actactacaa
     3601 gaaagacaag gtttaaataa gacaaataaa ctttatttag ttaaaccaga agtaacagaa
     3661 gatgatattt ataaaattca aaagcaagaa aacactgttg agagcagcaa tggcaaggaa
     3721 gtcggaaaaa ccgacttcaa gaagtcgata aaacagaatc taatgatact gaacttagct
     3781 atactgaatc taacaatact gaaataaatg atatgaatga cttgaatgat atagagtccg
     3841 aaaatgaaat tagtaatcat tcaagtcaat gcaaggttat ttaatgcaaa caattttaac
     3901 tgaatttgaa gaaacacatg cactttatat gcgccgtaaa aacatgaaac aatataacat
     3961 ctttaatcaa tcattcaaat gattttataa caatcaaaga tacatcaaaa tatttcgtta
     4021 aatcatctga ctttttaact gatagcgatg aaaaaatcaa gaaattgtca gtgatctaga
     4081 aaaagatttg tatcgaaaac gtatgttaag ttatggtgga ttgcttaaat aaaaacataa
     4141 aattttaaac ttagacgatg ctgaagatgg caatttaatt aatacaagtg atgaagataa
     4201 aatagcaaat gaagaagaaa aggcacattc gattacggca attttgaaaa gcaaaattat
     4261 tatttaaggc attagtgata actgatgtct ttttttatta cttttttgta aaaaaagtgc
     4321 tgtcttattt ttgtgacaaa tgctgtatgt agtgtcacaa aagtgtgaca cttgagcttt
     4381 ttatgacccc acacaaaaac attttcgaag ccttgaaata tctggctttg ccagatcccc
     4441 cattcattga tggggacaaa tttcccttat gctcttacgg agattttaga gttaaattaa
     4501 aatttctaag tttttgataa gaaaagccct gcaggaattt agaagaacgt ggggaagttt
     4561 taaagaattt tatgctaatt tttaatttgc atgtaaatgg gcagtgtcta aaaaatagtt
     4621 attgtttttg ctcaaatttt tgtttttgaa aatagcatat atttatttgg ctcatatttg
     4681 cgttttaaaa gcgtatataa gttttagata taaaactata tgaatcaccc ctaaatcttt
     4741 aaaatgccct cttaaaattc aaaataaggg cataaaaaat aaaagccccc ccagataaag
     4801 tgaggtagct ttttctttcg acgccgtatc gtcgatgtaa ttcaaaaaag ttatgggcta
     4861 taaatctaca tcactttttc aagaatgtag tagcaatatt caacgcaaat taatttttat
     4921 aactgctcgg aatatctcaa gccgtttctt taattttgaa ataaaaaaat cgacgaaggt
     4981 cgattacgtt tttgcacatg tcgatttatc cgacgtataa gtgcgccctt acgggattta
     5041 actagattat aacgacgaat tttagacctg taaagcaata acaattaggt ctaccaggta
     5101 gataaagtgt acaaagtaga accgaaaaag ttatttattt tgaagatttt tcgtagatat
     5161 aatttgctaa taaacttcct aaaactgaat aaagaaaaat agttaaactc atgtaatcac
     5221 tccataattc tgaagtgtct ccatgtctac gcatagacac gcatttatgc cgagaaaatt
     5281 tattgtgcgt tgagaagaac ccttaactaa acttgcagac gaatgtcggc atagcgtgag
     5341 ctattaagcc gaccattcga caagttttgg gattgttaag ggttccgagg ctcaacgtca
     5401 ataaagcaat tggaataaag cacctatgat tatttaaaaa tataagttat aatacattca
     5461 aaaatatttt gaatgaggtg tattatgatt caaacggttg ttgctgctgc tgttctttat
     5521 attgctacag cagttgattt attagtaatt ttattaatat tttttgctag agcaaagact
     5581 agaaaagaat atagaaatat ttatgttggt caatatttag ggtctattat tttaatatta
     5641 gttagtttgt ttttagcttt tgtattaaat tatgttccag aaaagtggat attaggttta
     5701 ttgggtttaa taccaattta tcttggaatt aaagtggcta tttatgatga ttgtgaagga
     5761 gaaaagagag ctaaaaaaga attgaatgaa aaaggattgt ctaaattagt tggtacggtt
     5821 gcaattgtta cgatagcaag ttgtggcgcc gataatattg gtttatttgt tccgtatttt
     5881 gtgacattaa gtgttactaa tttattactt actctgtttg tctttttaat tttaattttc
     5941 ttcttggtgt ttactgcaca aaaattagct aatatcccag gaattggaga aattgttgag
     6001 aaatttagtc gttggattat ggctatcatt tatatagctt taggtttatt tattattatt
     6061 gaaaatgaca ctattcaaac aattttagga tttatatttt aatttagggt gtgattttat
     6121 atgagttatg aaaatacttg tgatgtgatc tgtgtacatg aggataaagt taacaatgct
     6181 ttaagttttt tagaagatga taaatctaag aaattactta acattttaga aaaaatttgt
     6241 gatgagaaga aattgaaaat catattatct ttgattaaag aagatgagtt gtgtgtttgt
     6301 gatatttctt tgatattgaa aatgagtgtt gcttcaactt cacatcattt aaggctttta
     6361 tataaaaatg aggtacttga tttttataaa gatggaaaga tggcatatta ttttattaaa
     6421 gacgatgaaa taagagagtt tttctctaaa aatcaggagg gtttttgaaa cgagtgaaac
     6481 gagtttcttc ttgtcttgat actataaaaa acaaagttat ataacataag acgacttatc
     6541 ggaagttatc tatcatcgta tattcggaga tgatataata tacaggtcgc ctatctctca
     6601 ggcgtcaatt cagacgcaga gaggaggtgc attactttgc taatcatttt cgttcacatc
     6661 atagcaccag tcatcagtgg ctgtgctgtt gcgtattata cttattggct tagtaaacgc
     6721 aacaaataat taataggcga ctttataagc cagcatcgaa aaaatcccca cactattgca
     6781 gtagtgtggg gattggtgca ttaattgtta atcattttcg ttatctagat tataacactg
     6841 gttagtagag gaatgcaaaa agataatatt ttaagtagtc tttttggata ttatcatatg
     6901 atatatttat gtaaattgat tttttattaa aggagcatat atgagtaata ctaaaattaa
     6961 atatcaaatt tttatttcat caacttattt agatttaata gaagagcgtc aagcagtagt
     7021 agaagcagtt ttaaacagta ataatattcc agcaggtatg gaacttttta actcaagtag
     7081 taaaagccaa tgggaaataa taacacaatg gatcaatgaa tcagatgcag tgatattatt
     7141 gttaggttct agttatggaa caattgatag tgaagaaaat attagctata cagaaatgga
     7201 gtacaatttt gctaaatctt taggtaaacc tatatatgtt tttgagatga ataaagcatc
     7261 taccgaatcc gcggaaaagt ctaaaaaatt agatgagttt aagacaaaag ttaaagaaaa
     7321 tagtggatgg ataagagtac aggattgtgg taaaaatgta aaaaaattaa aaaaattgga
     7381 tgctatacaa agagatttag atacatatga ttttttgaaa gaagaacttt ataaaatatt
     7441 catgtatgta aaaacttttt atttccagca cacaccattt gatgatagtt atattgaaga
     7501 tatagaaaac tacctgctaa attatgaaaa taatccacat aaatcattca tgaaaataaa
     7561 agtttatgat tataaaaact ttttaaaaca tttaaaaaac atattgattt taattaaaca
     7621 aggaaaaaag ccattagctc aagccggtca ttttaaatta agcttttacg aagaggattt
     7681 aaaattgtta caaaaaaatt ataagactac gctagtcgat attaaaggat tgaataaaca
     7741 tttttataag gaatgtgata ggtgcttaaa agcatataat atttttattg agggtataaa
     7801 taaacattta tatgaatgat ataagtacac cctaatcata catatataat tgttgtcact
     7861 ttactcgata tatgagaatg actttaccta ataaatgaga aaagcaacgc actatattaa
     7921 aatgcgttgc tttttctatt atcgaatacc tataactaaa ctatctctag ctgtttctac
     7981 aacttctgta cttattttat ctaaaccatt tatatccata attctgtcta tctgcgcaaa
     8041 taaacgatga atcagcctaa aattcccttt tgtaatttta ataatcgtcg ttattgcctc
     8101 ataatcagta aagtcttcga gttttaaatc aaatcctaag tcttgccact tatattctaa
     8161 tatatgatgc gtctcatctt tacttagatt atcaaattca tgcgcaaaac ctatacgcga
     8221 atatagttga ggataacgag atagtttttt ctctataccc ggcataccaa taaatatcat
     8281 tgctaaatta tgttcatcat aaatagctct taattgctct aaatgttgca ctttaaggcg
     8341 atcaatctca tctactataa ttaaatcaat atatttaaac atatcactat aatgtttact
     8401 atgttcatgt ccatacttat ttacaacatg taatttttga cccaaatcaa tgattgcagt
     8461 aatactatat aaatcattcc ttaatttagt ttgtttttct gctggtgcat tataaaatat
     8521 tttatccacc gatagtatgt catcggtcgt tttactagct aaatcttccc aacctctatg
     8581 gttaacttgt ttttcaatag tatcccaatt tgtgtaatac ctagacgata aagtttttcc
     8641 gacaccaggt tgaccataac atataccaat atactgatat ttaatacaag catcacaaaa
     8701 ttcagcaaag cgtttatact ctttcgtttc aatgaaattt tgatttttag tcattacgat
     8761 atctctttaa ttttttgacg tttttagtcg tttcttgagg tgaataacca caattttttt
     8821 cttccttaat taattccgtg gtacttggac tagcaatatt ttgttttaag tgttttcttc
     8881 tctgactacg agcgtgctgt atgtctttta tatctatgga gtaatcagct atttctggac
     8941 atatagcagt acaaagaaat tcatctctat aaaacacacg tatttcagcc atatcatttg
     9001 ggttataacg aatcagtaca tattcaccta cataagcttc tagattagta ttactgtatc
     9061 gaaaaccttg aaaatgaatg ccatctgaat gaacttttct agatttaggt atttccaaca
     9121 ataataaatc aagttgttct aagctacttg gcatattagg gaaaaagtga ttactattcc
     9181 aatgactgat aggcgtggta tgaatagtac tatgttcttt ttgattataa tcttcaatta
     9241 aaaagtaacg taatttttct tcaaaattgt gaaaatttat tagattacta ggagtatcat
     9301 tattgtttat atatccaggc agttgttcta agaaagtttg attaactgtc tgaaagaatc
     9361 gttctatttt tccacgacca cgaggaacac caactttcga aaacatcaag ttaattttca
     9421 aatcaatagc gacttgttcc atatgatgtg aagtaaagtc acttccatga tctgtgtaga
     9481 atttttcggg tataccacac actggccaat tggtatcatt tttattccat attgcttggt
     9541 gtagtgttaa tgctgtgttt tgagcattgg ggggcatcaa aacttaagaa atagcctgca
     9601 attgcacgac tatagtcatc cataataata gttagccatg gtctattgat attacctttt
     9661 tggtctaata taaagatatc tagcaaagta tggtctgctt gccatatttc attgggtctc
     9721 gaggattctc taatttgtat taaatcgtac ttattttgat agtatttttc accctgatga
     9781 gagaaatcaa taacagactt aggcatcgct ttaataacac tataaatttg tttataactt
     9841 ggtatatcaa aattattttc tttacagtaa ttagtgattt tcctatgaat tgtggctata
     9901 ctatttcttt tattcataag cgcaaggcgt tcaatttcat caattatctt tggttctatt
     9961 ttacgtgttc ctttatcagc tcttgtcgca tagattagtc ctttaagtcc ttgttcttta
    10021 tatgacttat tccacctata aagggtgctt aacgcaatcc ctttactttt agaaatactt
    10081 gataaagatt gttcgcctag gataaaaggt tttataatat tgtacttttg agtagctttt
    10141 ttacgtttgg cttcagaaaa attagttaga tacttctcct tgtttttcat cttccttgtc
    10201 ctccaattta ttgaggtaac gataaattgt tgtacgtgaa acatgccact gttctgcaat
    10261 tgtcttaatt ggcgtgccat tatcataaag ggtcttaagt aagtttaaat ctttttgatt
    10321 taatttttct ggtctgcctc catatcggcc tctagcacgt gctgcaattc ggccagctga
    10381 agaacgctct aaaattaaat tacgttcaaa ttctgcaaat gctgcgaata aatgaaataa
    10441 taattgtcca gttgaacttg atttatccat tgttatattt tcttctaaac tatggaaact
    10501 tacacctcgt tcgttaagct cattaactaa tgtgattaaa tcctccatat tacgtcccaa
    10561 tctatctaat ctccaaacaa caatcgtatc tcctgacctc gcaaattcaa ttgctttatc
    10621 taaaccaggt cttttacttt ttgaaccact catatggtca ttaaatatct tttcacaacc
    10681 atatgtattt aatcgatcct cctgtaaatt taaattttgt aatccagttg aaactcttgc
    10741 ataacctatt ttcaaaatac aaacctccta tatacatctt cagtgtacca taacttaatt
    10801 acaaggtctt ttatgaacat agattttttg ttgggttttt gaacacataa tcctatgtaa
    10861 ttcttactta tttagacata aaagaagagt gtacagaaaa tggttatttt ctgtacactc
    10921 tcatctttaa taatatattt taaatgtcat taacaaaact aatttaataa gagtcaagca
    10981 tagtttacat atgtattatg tttgaaacat acctctaatt actttttact aatatcattt
    11041 aaaatatctc gcaattcttc aatttctttg ttatttaatt cttcattttt cgcaaaattc
    11101 aacactaaac ttttcatatc ccctccatac agtttattaa gaaaggtttt agcagttttc
    11161 attttaatat cgtcttcttt aatatttgat gagtaaaaat aaatattttc tgatttgtat
    11221 cgttttataa tctctttttt atatagtctt gtgattaatg ttctaatcgt tttatcacta
    11281 acttctttat atttttgaat ttcaactaca atttcattag ctgatactga ttttttatcc
    11341 catattatat tcataacatc ccattcagcc atagatattt caacttgctt attggccatt
    11401 taaaacaccc attcctttta atattttttc acttattaat tcagcatttt tcccagacgg
    11461 gtttccatct gataaatgtg tagcaaaata atacttatca tgatttgtaa ttacgtaacc
    11521 tacaaaccac ccattattat acttcccgtt tactatacct gtacctgttt tcccatacag
    11581 ttcatacttt tcatttttct taatcaataa tgaagaagat aattgattct ttgctttttt
    11641 actaaaatgg ttattttgtt ccatcatatt tttaaaaact attacttgtt caagattaga
    11701 tattttcaaa ctatcttcca tccaatagct tttataactt cccaaatttt cattaccata
    11761 atttaattac ttgagttgag ccgcagtata gttctttggt atttgattac taatacgttc
    11821 gaagtaccaa ttaactgaat tttgcattgc tgtatttaaa tcttgttcct tattccaaga
    11881 ctcgaaaaga taatgtttat gattccatga catacgtgaa tttttatcac ttataatatg
    11941 acggtcaagt ccaaacagtg ctaaataaat tttgtaagtt gaatcaggag aatatctttt
    12001 tctactttct ttttcattat aaatatagta tttgtctttc ttcatgctgt acataacgaa
    12061 agatccacta tttgaaccaa aatttttact ttcatctaaa atttggtaat cgctttgtaa
    12121 gggcttttta taattataat cagttaagga ttgccccatt aaaaactggc tttgaattat
    12181 catgataaaa aaagtaaaaa tacaaataaa aattagaatt aattttgact gctttttcag
    12241 atcggcttct tttatattaa ttaatctatt tttgagtaat gattttttac cattaaatga
    12301 atggcttaat atatttttgt tgaaaaatga ggtttttaat acggagtcca taatagattc
    12361 cgcataagtt ttaaattcat ttttgttaat attattaagg acaaatctat cggcttctac
    12421 ttcattgtca tgaattatct ttctttttac aatatgtact aatggattgt aactcataat
    12481 aatagagaag atattaaaga taattaaatg taaagtatct ctatttttag catgagcata
    12541 ttcatgcagt attatatatt ttagtctttt atcaattaca cttttaaaat atgaactagg
    12601 aatcaaaata atatatttcc cataccaaaa agttattgga gattgaatag cctctgcttt
    12661 tcgaatcaca atattttttt tatattgatg gttgaaaagt atcgtatcta ttttattttt
    12721 ttcattttcg tttagataaa gtgactgttt ctttaaatat ttaagatata ataaggcttt
    12781 caaaaattta aaacttaaaa taataactaa aactatccaa ataactgtgc agatattatc
    12841 aattgaatcc caattaaact tatggatatc tgttgcgaac tcttgaacag gtttggtggt
    12901 aattatgtta tggttcaagt cgtgtgactt actttcaact gtgggcgctt gattattcac
    12961 attattaaat tttataaaag agaatttaat tgggataaaa ggaattaatc cagcaagcac
    13021 agttagatac caaactttat aatttaaact ataattaaaa tagcgtttta atatgtacct
    13081 aaaaaatact aacaatagaa atataaaaca aaagcttact acactcatta ttagtaattt
    13141 agccattttg acaccttctt tcaaatattt ataataaaca attgacatca atattacaat
    13201 tgtaatatta ttgttttgta aaaattacaa ctgtaatatc ggagggttta ttttgaaaaa
    13261 gttaatattt ttaattgtaa tggctttagt tttaagtgca tgtaattcaa acagttcaca
    13321 tgccaaagag ttaaatgatt tagaaaaaaa atataatgct catattggtg tttatgcttt
    13381 agatactaaa agtggtaagg aagtaaaatt taattcagat aagagatttg cctatgcttc
    13441 gacttcaaaa gcgataaata gtgctatttt gttagaacaa gtaccttata ataagttaaa
    13501 taaaaaagta catattaaca aagatgatat agttgcttat tctcctattt tagaaaaata
    13561 tgtaggaaaa gacatcactt taaaagaact tattgaggct tcaatgacat atagtgataa
    13621 tacagcaaac aataaaatta taaaagaaat cggtggaatc aaaaaagtta aacaacgtct
    13681 aaaagaacta ggagataaag taacaaatcc agttagatat gagatagaat taaattacta
    13741 ttcgccaaag agcaaaaaag atacttcaac gcctgctgct ttcggcaaga ctttaaataa
    13801 acttatcgca aatggaaaat taagcaaaaa aaataaaaat ttcttacttg atttaatgtt
    13861 taataataaa aacggagaca ctttaattaa agatggtgtt ccaaaagact ataaggttgc
    13921 tgataaaagt ggtcaagcaa taacatatgc ttctagaaat gatgttgctt ttgtttatcc
    13981 taagggccaa tctgaaccta ttgttttagt catttttacg aataaagaca ataaaagtga
    14041 taagccaaat gataagttga taagtgaaac cgccaagagt gtaatgaagg aattttaata
    14101 ttctaaatgc ataataaata ctgataacat cttatagttt gtattatatt ttctattatc
    14161 gttgacatgt ataattttga tatcaaaacc tgattttccc tttattattt tcgagattta
    14221 ttttcttaat tctctttaac aaactagaaa tattgtatat acaaaaaatc ataaataata
    14281 gatgaatagt ttaattatag gtgttcatca atcgaaaaag caacgtatct tatttaaagt
    14341 gcgttgcttt tttctcattt ataaggttaa ataattctca tatatcaagc aaagtgacat
    14401 aattgttgaa tttatagtaa ctgaaacgta tgattagggt gtatattaat tatgagatgg
    14461 aaatcaatga ttgttggcta tgcgagagta tcatcgaacg atcaaaattt agaaagacaa
    14521 cttgaaaatt taaagacgtt ttgtgctgaa aaaatattta cagaaaaaca gtctgggaaa
    14581 tctattgaaa atagaccagt acttcaagaa gcacttaact ttttgaggat gggagatcgg
    14641 tttgtagtag aatccattga ttgtttaggt cgtaattatg atgaagtgat tcataccgtt
    14701 aattatttaa aagacaaaga agtacaatta atgattacta gcttacctat gatgaatgaa
    14761 gtggttggca atccattact ggataagttt atgaaagatt taattattca aatattagca
    14821 atggtttcag aacaagagag aaatgaaagt aaacgtcgac aagcgcaagg aattcaagtt
    14881 gcgaaggaaa aaggcgtata taaagggcgc cccttacttt attcaccaaa tgctaaagat
    14941 ccacagaaac gtattattta tcatcgcgtt gtagaaatgt tagaagaagg ccaatcaatt
    15001 agtaaaattg cgaaagaagt aaatataaca aggcagacga tttacagaat taaaaacgat
    15061 aatgatttga tttaataaac tttgtttcaa tgcaactgag agcttctcac agcgtctcaa
    15121 aacagatgat tataatctat tatgagtttt taataataag acaagaaaag agagcgtaaa
    15181 tatgctctct ctttttctca ttaacgaatg tttataacgc aatcatgatg agagtattaa
    15241 tacagttaat tatttgaaat actttagttt atataatgtt gaattatagg tagtgaaatt
    15301 gtatttatta tacattgtca tatcgttgtt taatgatagt taatttaagg ataatagaat
    15361 taatattata tatagatgaa caaaacaagc aacagagcag aaaaaacact tttagattat
    15421 ttttactcat tctctatttt atttattttt gctataataa ataaagaata ttaaatggag
    15481 gtgtttttat gaaaaagaaa tttgtttcta gttgtattgc tagtacaatc ttattcggca
    15541 ctttattagg tgtaacttat aaagctgaag ctgcaacagt acatgtagct ggtggtgttt
    15601 ggagccatgg tattggaaaa cattacgtat ggtcttatta tagtcacaat aaaagaaatc
    15661 atggttcaac agcagtaggg aaatattcat cttttagtgg tgttgctcga cctggtgttc
    15721 aatctaaggc atctgctcca aaggcttggg gtggaaacaa aacattttat agtcttcact
    15781 aattacatat attaattaag gagaatagac agaattaagt aaacttaatt ctgtctattc
    15841 tcttgaaaga ggcaatatga aaaaattcaa attattttta gattttagta ctttattatt
    15901 aatttcaggg ctattatttt tatttttctt caaagaaaat gaagaaatta tacctgaaag
    15961 ttccaatatt ttaacaatct ctaattggga taaatctaac agtaaatcaa aagtgttaga
    16021 tgtcattgaa tcaggcgcca aaaatcaaaa tatacaaata attaaatccg ttaaagattt
    16081 tgataataaa aaagaatttt ttgttttcaa ctcaaaacga aataattctg actttatacg
    16141 taataaaaca tcacttttaa ctccatcaga tttattaaac agagagataa aaggaaagta
    16201 ttatattatt ggtgaacatt tcaatgtaga agagcttacg agtgaattaa aaaaagctgg
    16261 tttaacatct gaagttgaat acataaatag aaacatatta ttttttgaat tagtcataga
    16321 taatgattta ttagtgcctt tcatattctt aggcgtatta tatcttttgt acttcttata
    16381 tgacagagga tataatttga aattttatgc tattcaaaag ctacatggct tttcaactac
    16441 acgcattatt tttcataata ttcatataaa aatcatttat tggctagtac ttaccgctat
    16501 tttctttatt gctaatatat taatcattca tatagccaat ttagaattgg atttcttaat
    16561 gtttattcgt agatttatcg tgttgctttt tgtttttgct tgtattacta cattgctgtg
    16621 gctgatttcg tatagtcttc ttttgaagtt aagtattcca ttaatcttaa aagggaaaaa
    16681 aggatataag ttttcaatat ttatgggtac cttcaccaaa tgtatcatgg tgctaatact
    16741 atctttttta ctggcacaaa atttaaatgc ttatacgaag ttaaagaata tatatgactc
    16801 tgaaaaaatc tggcaaaagt tagataatta ctatacatta gagatttctc ctaatattag
    16861 aaattcagaa gaaaaacaaa ttttagaaac taatatatac aatttaatta agaaaagcga
    16921 acaacttggt ggattgcttt taaagaataa taatatagcc aatcccgata aaaacaatta
    16981 cattcctgaa aatggcaatg tcttttttat caataacaat tttctgaatt tctataaaaa
    17041 tataaatcat gattttaaaa tgattgacaa tcattcggat aaaataaacg tgtttattcc
    17101 tccaaggtta caatatcaaa aatctgaaat tcaaaaaaat caccaaggat ggattgactt
    17161 tcaaaagcaa caaaacaaaa aagtagatgt gcaagtactg tcaaaaaacg tatctgtttt
    17221 ttcttttgat cgcacaacta atttgaaatt tgggtatcta gattctccaa tagtaatgtt
    17281 gttgacactt gacgatttaa caggagattt ttatttagct gctgtttctc aaggtggata
    17341 tctatttaaa gatttagata cacttaaaca gttgcttaaa gataatcacc tagaagaaga
    17401 aattagcggt ataactaatt acaaggattc tgtgttaaat gaattaaatg aaacgaaaac
    17461 aaaaatgata ataacaatag ttactattat tattaacgtt ttcattcttt tgatagctac
    17521 tgtatttgaa acaattcaat attttagctg gaataaaaag caactattat taagaaaaat
    17581 tcatggttat tcattattca gcagtaatgt acgttattta acaatttcta tcttactttc
    17641 tattatgtta gcttacacta cgcatatttt atttggttca aagatattac tattcataat
    17701 aatgtctatt gctattattc aacatttact tcaaattgct tatattaaat atcttgaaaa
    17761 atactttaaa gatttaatga gggagattta aacaatgaaa agaactttaa ttattgtaac
    17821 aattgtacta ttaatcatca tacttagtct gttattggtt agaaatgagc atttagatcg
    17881 ttttaaccca ctgttaaaag aaaaagtatc ttatgccaaa gttccaaaag atacccagga
    17941 ctatagaaat ataactgtat actctaaaaa tggagaaaaa aagagttata aattggattt
    18001 tttaggttat gatcctacaa aagaatatgt gaaagtaaat cataaaggga aatatgtgcg
    18061 ttcgatagaa tacattacaa aagatattcc tagcttttta aaatgaggtg accgatagtg
    18121 ataaaacttg aaaatgtttt tgtaaaaaaa ggtaataaaa acattttaga cggatgtaac
    18181 tttaattttg aaaaaggaaa atcatatgct ttagttggag aaagtggcgc tggaaaatct
    18241 actttactta acataatcgc tgggttcgaa gatgtatcac aaggaagcat atatattgaa
    18301 gataagttac taaaaaagaa agtcgatttt tatagatata cgttagggta tttgtttcaa
    18361 aattttgctt tacttgaaaa tcaaacaatc agtcaaaatt tagatttagc cctaaagttc
    18421 aaaaagaata aaaaagataa tatgaactta aagaaagaag tattaaaaaa ggtcggccta
    18481 gatttagata tcaagagaat tgttagttct ctaagcggtg gtgaacaaca aagagtagca
    18541 ttggcaagat taatattaaa agatccgaaa atcattttag ctgatgaacc tactgggtca
    18601 ctagatacga aaaatggaaa aatagttatt gatttattat tgaagctact tgatgaaaat
    18661 aaaactatga ttgtcgtaac gcatgattta gagcttgcga aacgatttga tgtcatagtc
    18721 aatatttctg agcttagaag ttaagaaata ttgataggta tagccataca tagagaaaaa
    18781 acaatatgaa atatgattag tcattacttt tgagtttttt aatttaagga ctggattttc
    18841 cagtcctttt ttatgatgac aaaaaacaag cctcgcagag cacacgtttt taatgactta
    18901 tttggttttt aataagtcta gtatgttaaa acttttctgt gtttaggtgt tataatcata
    18961 tgcagtggaa gttgatttat tatgtcttat tcaattattc gagttgttaa agtgaaatca
    19021 aaaacaaata caagaggtat tcaaagacat attcaaagag aaaataaaaa ttatgaaaat
    19081 atagatattg atttaagtaa gtcatattta aactatgatt tagtcaatga tactaagttt
    19141 gattttaata aaaaaattga tgagaaaatc gaaaaaaatt ataaagggaa acgcaaaatt
    19201 agaacagatg ccattaaaca tattgatgga ttaattacat cagataatgt gttttttaat
    19261 caattatctg aagaagagac aaaatagttt tttaagcatg ctaaagcgtt cttggaagaa
    19321 gaatacggta aagaaaatct tttatatgcg acagtacata tggatgagat aacaccacat
    19381 atgcattatg gcgtagttcc tattactaaa gatggacgtt taagtgcgaa agaagttgta
    19441 ggtaataaaa aagcattaac cgaattccaa gatagattca atacgtatat taataagcaa
    19501 ggctatgatt taaaacgagg aatttctaga caacttacaa aagaaaaaca tgatcaagtt
    19561 agccgttata aacaaaaaac agaatatcat aaacaaatgc atatgcgcta gaagcaaata
    19621 gaggattatt taaagcaaga aaatgataaa ttgatacaaa actaccaaaa atcattagat
    19681 acgcttaaaa agcttctgag tgtcatgtat gaaattaaaa ctaaaaatgt aggtggatgg
    19741 tttcataaag agaagcaaga aacaggcaat attgtaatta ctaaaactga ttttgaaaaa
    19801 tacactaaac aaattaaagc agcacagatg atattagatg attatgaatg tattaaaagt
    19861 gggaagtcat taaaaaaagc agagaaacaa aatgaaagtt tagttaatga attgactagt
    19921 gtccatatgg aaaatgaaaa gctggttgaa gaatttaatg atttagcaca acgttataat
    19981 tatttgttgt cagagaatga aaagaaagat aaagaactaa attatacgct taagttattc
    20041 aatcaagttt ttaaaatcat taaaagtatg atgaaagaag agcgttatca tacactaata
    20101 aatcatattg ataatcattt agacaattct aaaatacgtg aagtaatgac gatagataac
    20161 aatgatgaac agttctttaa gaagaaatat caagcacaag aacgagaaat catttttaaa
    20221 gaagatagag aagatggtta tacattataa aaatagatat ttaaatgcat ttgtttgagg
    20281 ttaattattt tttaggatga aaaataggta gcccccctcg aactttttaa tatattttta
    20341 taaatctttt taaaaacctt tttaggggct tgttcagccc tagagcaaca agggatttca
    20401 atgcctaaag gagtgttttt gccacataaa aggagtgttt ttgccacata aaaggagtgt
    20461 ttttgccaca taaaaggagt gtttttgcca cataaaagga gtgttttaaa aagttgtact
    20521 ccttttatgg tttgacattg ataataaagt agtttattgt gaataaaagt tttcaaatgg
    20581 gagtgtatat tcaaacgata ctcctttagg ttcgtaataa agggggctgt atc
//
