LOCUS       NZ_CP012736            24419 bp    DNA     circular CON 03-MAR-2024
DEFINITION  Shigella flexneri 1a strain 0228 plasmid unnamed, complete sequence.
ACCESSION   NZ_CP012736
VERSION     NZ_CP012736.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN03797406
            Assembly: GCF_001578125.1
KEYWORDS    RefSeq.
SOURCE      Shigella flexneri 1a
  ORGANISM  Shigella flexneri 1a
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Shigella.
REFERENCE   1  (bases 1 to 24419)
  AUTHORS   Pu,X.
  TITLE     Complete nucleotide sequence of a multiple drug resistant Shigella
            flexneri 1a 0228
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 24419)
  AUTHORS   Pu,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-SEP-2015) Microbiology Laboratory, Hangzhou Center for
            Disease Control and Prevention, Mingshi Road, Jianggan District,
            Hangzhou, Zhejiang 310021, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: smrtanalysis v. 2.3.0.140936
            Genome Coverage                   :: 164.55
            Sequencing Technology             :: PacBio RS
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/03/2024 09:49:47
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,989
            CDSs (total)                      :: 4,852
            Genes (coding)                    :: 4,125
            CDSs (with protein)               :: 4,125
            Genes (RNA)                       :: 137
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 108
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 727
            CDSs (without protein)            :: 727
            Pseudo Genes (ambiguous residues) :: 0 of 727
            Pseudo Genes (frameshifted)       :: 295 of 727
            Pseudo Genes (incomplete)         :: 368 of 727
            Pseudo Genes (internal stop)      :: 168 of 727
            Pseudo Genes (multiple problems)  :: 100 of 727
            Pseudo Genes (short protein)      :: 5 of 727
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP012736.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..24419
                     /organism="Shigella flexneri 1a"
                     /mol_type="genomic DNA"
                     /strain="0228"
                     /host="Homo sapiens"
                     /db_xref="taxon:374923"
                     /plasmid="unnamed"
                     /geo_loc_name="China"
                     /collection_date="2002"
     gene            complement(join(<24419..<24419,1..260))
                     /locus_tag="AOT98_RS25870"
                     /old_locus_tag="AOT98_25940"
                     /pseudo=""
     CDS             complement(join(<24419..<24419,1..260))
                     /locus_tag="AOT98_RS25870"
                     /old_locus_tag="AOT98_25940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309639.1"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein P"
                     /name="replication protein P"
     gene            complement(232..1156)
                     /locus_tag="AOT98_RS25875"
                     /old_locus_tag="AOT98_25945"
                     /pseudo=""
     CDS             complement(232..1156)
                     /locus_tag="AOT98_RS25875"
                     /old_locus_tag="AOT98_25945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311014.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /name="replication protein"
     gene            complement(1191..1472)
                     /locus_tag="AOT98_RS25880"
                     /old_locus_tag="AOT98_25950"
     CDS             complement(1191..1472)
                     /locus_tag="AOT98_RS25880"
                     /old_locus_tag="AOT98_25950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015995142.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CII family transcriptional regulator"
                     /protein_id="WP_000536662.1"
                     /translation="MGTIATKSKKAARIESALLNKLALMGQKTFARAMGVPEYQVSRWK
                     NGFFSQVSMMLAVLEYGIEDDEMAELTKRLADYLTKEKAPKNGEFFEA"
                     /name="CII family transcriptional regulator"
     gene            complement(1589..1804)
                     /locus_tag="AOT98_RS25885"
                     /old_locus_tag="AOT98_25955"
     CDS             complement(1589..1804)
                     /locus_tag="AOT98_RS25885"
                     /old_locus_tag="AOT98_25955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194218.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_001194218.1"
                     /translation="MQTLSERLKKRRIALKMTQTELATKAGVKQQSIQLIEAGVTKRPR
                     FLFEIAMALNCDPVWLQYGTKRGKAA"
                     /name="helix-turn-helix transcriptional regulator"
     gene            1908..2540
                     /locus_tag="AOT98_RS25890"
                     /old_locus_tag="AOT98_25960"
     CDS             1908..2540
                     /locus_tag="AOT98_RS25890"
                     /old_locus_tag="AOT98_25960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028393.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LexA family transcriptional regulator"
                     /protein_id="WP_000028392.1"
                     /translation="MSISSRVKSKRIQLGLNQAELAQKVGTTQQSIEQLENGKTKRPRF
                     LPELASALGVSVDWLLNGTSDSNVRFVGHVEPKGKYPLISMVRAGSWCEACEPYDIKDI
                     DEWYDSDVNLLGDGFWLKVEGDSMTSPVGQSIPEGHMVLVDTGREPVNGSLVVAKLTDA
                     NEATFKKLVIDGGQKYLKGLNPSWPMTPINGNCKIIGVVVEARVKFV"
                     /name="LexA family transcriptional regulator"
     gene            2630..2941
                     /locus_tag="AOT98_RS25895"
                     /old_locus_tag="AOT98_25965"
     CDS             2630..2941
                     /locus_tag="AOT98_RS25895"
                     /old_locus_tag="AOT98_25965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001434479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001379071.1"
                     /translation="MNGDRYEFTKDSTEDSVFHVTINGDKSSVYESVSGVYPEMKYTAL
                     SSNTMVGEYQSGGGITVETWSITTDKKALYSKVMNIPGMQQLTSTKSFVGDVVGTCNQ"
                     /name="hypothetical protein"
     gene            2995..3159
                     /locus_tag="AOT98_RS29920"
     CDS             2995..3159
                     /locus_tag="AOT98_RS29920"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_167694435.1"
                     /translation="MEFVFHAHFYNISCLQHTIFLVILSHQQDALTTIEGEALKNLALK
                     KGSIQSRKL"
                     /name="hypothetical protein"
     gene            3246..3572
                     /locus_tag="AOT98_RS25900"
                     /old_locus_tag="AOT98_25970"
     CDS             3246..3572
                     /locus_tag="AOT98_RS25900"
                     /old_locus_tag="AOT98_25970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001296860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitermination protein N"
                     /protein_id="WP_000340008.1"
                     /translation="MDAQTRRRERRAEKQAQWKAANPLLVGVSAKPVNRPILSLNRKPK
                     SRVESALNPIDLTVLAEYHEQIESNLQRIERKNQRTWYSKPRSEMGVTCVGRQKMKLGS
                     KPLI"
                     /name="antitermination protein N"
     gene            3584..4207
                     /locus_tag="AOT98_RS25905"
                     /old_locus_tag="AOT98_25975"
     CDS             3584..4207
                     /locus_tag="AOT98_RS25905"
                     /old_locus_tag="AOT98_25975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001597931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nmad5 family putative nucleotide modification
                     protein"
                     /protein_id="WP_061440231.1"
                     /translation="MSSIRLTTRMKEEIARNALIKSGVFTELEEVTKLKNQLALDARVI
                     AFGGKKKTEEVDQLSSKLVAISEELGKMGCSFYSYDVRSTSIYLTVSGRRVGWLPYGKD
                     GNGEDILLPTPNKDKCMFSAEHEITKRFDEICALQQKLEAKKKDIESNVWAALNSVTTV
                     KRLIEVWPESKELLPKEADKASTALPALRVEDLNKMIGLPSEAA"
                     /name="Nmad5 family putative nucleotide modification
                     protein"
     gene            4429..4593
                     /locus_tag="AOT98_RS29540"
     CDS             4429..4593
                     /locus_tag="AOT98_RS29540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease FtsH-inhibitory lysogeny factor CIII"
                     /protein_id="WP_001198861.1"
                     /translation="MQYAIAGWPVAGCPSESLLERITRKLRDGWKRLIDILNQPGVPKN
                     GSNTYGYPD"
                     /name="protease FtsH-inhibitory lysogeny factor CIII"
     gene            4562..4705
                     /gene="kil"
                     /locus_tag="AOT98_RS29545"
                     /old_locus_tag="AOT98_25980"
     CDS             4562..4705
                     /gene="kil"
                     /locus_tag="AOT98_RS29545"
                     /old_locus_tag="AOT98_25980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309204.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="host cell division inhibitory peptide Kil"
                     /protein_id="WP_000372937.1"
                     /translation="MDQTLMAIQTKFTIATFIGDEKMFREAVDAYKKWILILKLRSSKS
                     IH"
                     /name="kil"
     gene            4780..5076
                     /locus_tag="AOT98_RS25915"
                     /old_locus_tag="AOT98_25985"
     CDS             4780..5076
                     /locus_tag="AOT98_RS25915"
                     /old_locus_tag="AOT98_25985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309203.2"
                     /GO_function="GO:0060703 - deoxyribonuclease inhibitor
                     activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="host-nuclease inhibitor Gam family protein"
                     /protein_id="WP_032357385.1"
                     /translation="MNAYYIQDRIEAQSWARHYQQIAREEKEAELADDMEKGLPQHLFE
                     SLCIDHLQRHGASKKAITRAFDDDVEFQERMAEHIRYMVETIARHQVDIDSEV"
                     /name="host-nuclease inhibitor Gam family protein"
     gene            5082..5867
                     /gene="bet"
                     /locus_tag="AOT98_RS25920"
                     /old_locus_tag="AOT98_25990"
     CDS             5082..5867
                     /gene="bet"
                     /locus_tag="AOT98_RS25920"
                     /old_locus_tag="AOT98_25990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309202.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006259 - DNA metabolic process [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage recombination protein Bet"
                     /protein_id="WP_000100845.1"
                     /translation="MSTALATLAGKLAERVGMDSVDPQELITTLRQTAFKGDASDAQFI
                     ALLIVANQYGLNPWTKEIYAFPDKQNGIVPVVGVDGWSRIINENQQFDGMDFEQDNESC
                     TCRIYRKDRNHPICVTEWMDECRREPFKTREGREITGPWQSHPKRMLRHKAMIQCARLA
                     FGFAGIYDKDEAERIVENTAYTAERQPERDITPVNDETMQEINTLLIALDKTWDDDLLP
                     LCSQIFRRDIRASSELTQAEAVKALGFLKQKASEQKVAA"
                     /name="bet"
     gene            5864..6544
                     /locus_tag="AOT98_RS25925"
                     /old_locus_tag="AOT98_25995"
     CDS             5864..6544
                     /locus_tag="AOT98_RS25925"
                     /old_locus_tag="AOT98_25995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lambda exonuclease family protein"
                     /protein_id="WP_054428303.1"
                     /translation="MTPDIILQRTGIDVRAVEQGDDAWHKLRLGVITASEVHNVIAKPR
                     SGKKWPDMKMSYFHTLLAEVCTGVAPEVNAKALAWGKQYENDARVLFEFTSGVNVTESP
                     IIYRDESMRTACSPDGLCSDGNGLELKCPFTSRDFMKFRLGGFEAIKSAYMAQVQYSMW
                     VTRKDAWYFANYDPRMKREGLHYVVVERDENYMASFDEMVPEFIEKMDEALAEIGFVFG
                     EQWR"
                     /name="lambda exonuclease family protein"
     gene            6541..6723
                     /locus_tag="AOT98_RS28760"
     CDS             6541..6723
                     /locus_tag="AOT98_RS28760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311030.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1317 domain-containing protein"
                     /protein_id="WP_000682304.1"
                     /translation="MKHPHDNIRVGAITFVYSVTKRGWVFPGLSVIRNPLKAQRLAEEI
                     NNKRGAVCTKHLLLN"
                     /name="DUF1317 domain-containing protein"
     gene            6696..6887
                     /locus_tag="AOT98_RS25930"
                     /old_locus_tag="AOT98_26000"
     CDS             6696..6887
                     /locus_tag="AOT98_RS25930"
                     /old_locus_tag="AOT98_26000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1382 family protein"
                     /protein_id="WP_000548528.1"
                     /translation="MHKASPVELRTSIEMAHSLAQIGVRFVPIPVETDEEFHTLAASLS
                     QKLEMMAAKAEANERDPA"
                     /name="DUF1382 family protein"
     gene            6964..7179
                     /locus_tag="AOT98_RS25935"
                     /old_locus_tag="AOT98_26005"
     CDS             6964..7179
                     /locus_tag="AOT98_RS25935"
                     /old_locus_tag="AOT98_26005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_061440230.1"
                     /translation="MTPQQENALRSIARQANSEIKNARQQFPDKNVDDICRSVLKKHRE
                     TVALMGFTPTHLSLAIGMLNGVFKER"
                     /name="hypothetical protein"
     gene            7278..7496
                     /locus_tag="AOT98_RS28765"
     CDS             7278..7496
                     /locus_tag="AOT98_RS28765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016246897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA family transcriptional regulator"
                     /protein_id="WP_061440229.1"
                     /translation="MADIIDSASEIEELQRNTAIKMRRLNHQAISATHCCECGDPIDEL
                     RRLAVQGCRTCASCQEEIELKNKQWGL"
                     /name="TraR/DksA family transcriptional regulator"
     gene            7544..7822
                     /locus_tag="AOT98_RS25940"
                     /old_locus_tag="AOT98_26010"
     CDS             7544..7822
                     /locus_tag="AOT98_RS25940"
                     /old_locus_tag="AOT98_26010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016248605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4222 domain-containing protein"
                     /protein_id="WP_000488407.1"
                     /translation="MFRIIFPNTWYVDHHGTPCKILRSTHNKVHYIRKGRTCIASMFRF
                     NHDFEPVNKADADRIAEEIETAEHIKKLRDMRSKSRGNHGIIQPHTR"
                     /name="DUF4222 domain-containing protein"
     gene            7794..8144
                     /locus_tag="AOT98_RS30545"
     CDS             7794..8144
                     /locus_tag="AOT98_RS30545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443634.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_000446902.1"
                     /translation="MESYSLTLDEACQFLKISRPTATNWIRTGRLQATRKDPTKPKSPY
                     LTTRQACIAALQSPLHTIKVSAGDGITEERKCHSSAEVKYGTPVSHCRTVKDLNSLLEQ
                     RTKGRRQNSMTS"
                     /name="helix-turn-helix domain-containing protein"
     gene            8066..9184
                     /locus_tag="AOT98_RS25945"
                     /old_locus_tag="AOT98_26015"
     CDS             8066..9184
                     /locus_tag="AOT98_RS25945"
                     /old_locus_tag="AOT98_26015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706266.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA];
                     GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="WP_001132557.1"
                     /translation="MPNGKRFKQSLGTKDKRQATELHDKLKAEAWRVSKLGEIPDITFE
                     EACVRWLEEKAHKKSLDDDKSRIGFWLQHFAGMQLRDITESKIYSAMQKMTNRRHEENW
                     KLRAEACRKKGKPVPEYTPKPASVATKATHLSFIKALLRAAEREWKMLDKAPIIKVPQP
                     KNKRIRWLEPHEAQRLIDECPEPLKSVVEFALATGLRRSNIINLEWQQIDMQRRVAWIN
                     PEESKSNRAIGVALNDTACRVLKKQIGNHHRWVFVYKESCTKPDGTKAPTVRKMRYDAN
                     TAWKAALRRAGIDDFRFHDLRHTWASWLVQAGVPLSVLQEMGGWESIEMVRRYAHLAPN
                     HLTEHARQIDSILNPSVPNLSQSKNKEGTNDV"
                     /name="tyrosine-type recombinase/integrase"
     gene            complement(9199..9274)
                     /locus_tag="AOT98_RS25950"
                     /old_locus_tag="AOT98_26020"
     tRNA            complement(9199..9274)
                     /locus_tag="AOT98_RS25950"
                     /old_locus_tag="AOT98_26020"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9239..9241),aa:Thr,seq:cgt)
                     /name="tRNA-Thr"
     gene            complement(9389..10642)
                     /gene="proA"
                     /locus_tag="AOT98_RS25955"
                     /old_locus_tag="AOT98_26025"
     CDS             complement(9389..10642)
                     /gene="proA"
                     /locus_tag="AOT98_RS25955"
                     /old_locus_tag="AOT98_26025"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706245.1"
                     /GO_function="GO:0004350 - glutamate-5-semialdehyde
                     dehydrogenase activity [Evidence IEA]"
                     /GO_process="GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="WP_000893267.1"
                     /translation="MLEQMGIAAKQASYKLAQLSSREKNRVLEKIADELEAQSEIILNA
                     NAQDVADARANGLSEAMLDRLALTPARLKGIADDVRQVCNLADPVGQVIDGGVLDSGLR
                     LERRRVPLGVIGVIYEARPNVTVDVASLCLKTGNAVILRGGKETCRTNAATVAVIQDAL
                     KSCGLPAGAVQAIDNPDRALVSEMLRMDKYIDMLIPRGGAGLHKLCREQSTIPVITGGI
                     GVCHIYVDESAEIAEALKVIVNAKTQRPSTCNTVETLLVNKNIADSFLPALSKQMAESG
                     VTLHADAAALTQLQAGPAKVVAVKAEEYDDEFLSLDLNVKIVSDLDDAIAHIREHGTQH
                     SDAILTRDMRNAQRFVNEVDSSAVYVNASTRFTDGGQFGLGAEVAVSTQKLHARGPMGL
                     EALTTYKWIGIGDYTIRA"
                     /name="proA"
     gene            complement(10654..11757)
                     /gene="proB"
                     /locus_tag="AOT98_RS25960"
                     /old_locus_tag="AOT98_26030"
     CDS             complement(10654..11757)
                     /gene="proB"
                     /locus_tag="AOT98_RS25960"
                     /old_locus_tag="AOT98_26030"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706244.2"
                     /GO_function="GO:0004349 - glutamate 5-kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="WP_001285281.1"
                     /translation="MSDSQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQLHAAGHRI
                     VIVTSGAIAAGREHLGYPELPATIASKQLLAAVGQSRLIQLWEQLFSIYGIHVGQMLLT
                     RADMEDRERFLNARDTLRALLDNNIVPVINENDAVATAEIKVGDNDNLSALAAILAGAD
                     KLLLLTDQKGLYTADPRRNPQAELIKDVYGIDDALRAIAGDSVSGLGTGGMSTKLQAAD
                     VACRAGIDTIIAAGSKPGVIGDVMEGISVGTLFHAQATPLENRKRWIFGAPPAGEITVD
                     EGATAAILERGSSLLPKGIKSVTGNFSRGEVIRICNLEGRDIAHGVSRYNSDALRRIAG
                     HHSQEIDAILGYEYGPVAVHRDDMITR"
                     /name="proB"
     gene            complement(11948..12645)
                     /locus_tag="AOT98_RS25965"
                     /old_locus_tag="AOT98_26035"
     CDS             complement(join(11948..12396,12396..12645))
                     /locus_tag="AOT98_RS25965"
                     /old_locus_tag="AOT98_26035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558153.1"
                     /ribosomal_slippage=""
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
                     /protein_id="WP_223368647.1"
                     /translation="MASISIRCPSCSATEGVVRNGKSTAGHQRYLCSHCRKTWQLQFTY
                     TASQPGTHQKIIDMAMNGVGCRASARIMGVGLNTVLRHFKKLRPQSVTSRIQPGSDVIV
                     CAEMDEHWGYVGAKSRQRWLFYAYDRIRRTVVAHVFGERTLATLERLLSLLSAFEVVVW
                     MTDGWPLYESRLKGKLHVISKRYTQRIERHNLNLRQHLARLGRKSLSFSKSVELHDKVI
                     GHYLNIKHYQ"
                     /name="IS1 family transposase"
     gene            12821..13876
                     /gene="phoE"
                     /locus_tag="AOT98_RS25970"
                     /old_locus_tag="AOT98_26040"
     CDS             12821..13876
                     /gene="phoE"
                     /locus_tag="AOT98_RS25970"
                     /old_locus_tag="AOT98_26040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706241.2"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015288 - porin activity [Evidence IEA]"
                     /GO_process="GO:0034220 - monoatomic ion transmembrane
                     transport [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoporin PhoE"
                     /protein_id="WP_000749864.1"
                     /translation="MKKSTLALVVMGIVASASVQAAEIYNKDGNKLDVYGKVKAMHYMS
                     DNASKDGDQSYIRFGFKGETQINDQLTGYGRWEAEFAGNKAESDTAQQKTRLAFAGLKY
                     KDLGSFDYGRNLGALYDVEAWTDMFPEFGGDSSAQTDNFMTKRASGLATYRNTDFFGVI
                     DGLNLTLQYQGKNENRDVKKQNGDGFGTSLTYDFGGSDFAISGAYTNSDRTNEQNLQSR
                     GTGKRAEAWATGLKYDANNIYLATFYSETRKMTPITGGFANKTQNFEAVAQYQFDFGLR
                     PSLGYVLSKGKDIEGIGDEDLVNYIDVGATYYFNKNMSAFVDYKINQLDSDNKLNINND
                     DTVAVGMTYQF"
                     /name="phoE"
     gene            complement(13915..14316)
                     /gene="crl"
                     /locus_tag="AOT98_RS25975"
                     /old_locus_tag="AOT98_26045"
     CDS             complement(13915..14316)
                     /gene="crl"
                     /locus_tag="AOT98_RS25975"
                     /old_locus_tag="AOT98_26045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706240.1"
                     /GO_process="GO:0045893 - positive regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-binding protein Crl"
                     /protein_id="WP_000174678.1"
                     /translation="MTLPSGHPKSRLIKKFTALGPYIREGKCEDNRFFFDCLAVCVNVK
                     PAPEVREFWGWWMELEAQESRFTYSYQFGLFDKAGDWKSVPVKDTEVVERLEHTLREFH
                     EKLRELLTTLNLKLEPANDFRDEPVKLTA"
                     /name="crl"
     gene            complement(14374..15618)
                     /gene="frsA"
                     /locus_tag="AOT98_RS25980"
                     /old_locus_tag="AOT98_26050"
     CDS             complement(14374..15618)
                     /gene="frsA"
                     /locus_tag="AOT98_RS25980"
                     /old_locus_tag="AOT98_26050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706239.1"
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase FrsA"
                     /protein_id="WP_000189558.1"
                     /translation="MTQANLSETLFKPRFKHPETSTLVRRFNHGAQPPVQSALDGKTIP
                     HWYRMINRLMWIWRGIDPREILDVQARIVMSDAERTDDDLYDTVIGYRGGNWIYEWATQ
                     AMVWQQKACTEEDPQLSGRHWLHAATLYNIAAYPHLKGDDLAEQAQALSNRAYEEAAQR
                     LPGTMRQMEFTVPGGAPITGFLHMPKGDGPFPTVLMCGGLDAMQTDYYSLYERYFAPRG
                     IAMLTIDMPSVGFSSKWKLTQDSSLLHQHVLKALPNVPWVDHTRVAAFGFRFGANVAVR
                     LAYLESPRLKAVACLGPVVHTLLSDFKCQQQVPEMYLDVLASRLGMHDASDEALRVELN
                     RYSLKVQGLLGRRCPTPMLSGYWKNDPFSPEEDSRLITSSSADGKLLEIPFNPVYRNFD
                     KGLQEITGWIEKRLC"
                     /name="frsA"
     gene            complement(15710..16167)
                     /gene="gpt"
                     /locus_tag="AOT98_RS25985"
                     /old_locus_tag="AOT98_26055"
                     /pseudo=""
     CDS             complement(15710..16167)
                     /gene="gpt"
                     /locus_tag="AOT98_RS25985"
                     /old_locus_tag="AOT98_26055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308292.1"
                     /GO_function="GO:0000310 - xanthine
                     phosphoribosyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /name="gpt"
     gene            16429..17886
                     /gene="pepD"
                     /locus_tag="AOT98_RS25990"
                     /old_locus_tag="AOT98_26060"
     CDS             16429..17886
                     /gene="pepD"
                     /locus_tag="AOT98_RS25990"
                     /old_locus_tag="AOT98_26060"
                     /EC_number="3.4.13.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706237.1"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosol nonspecific dipeptidase"
                     /protein_id="WP_001293030.1"
                     /translation="MSELSQLSPQPLWDIFAKICSIPHPSYHEEQLAEYIVGWAKEKGF
                     HVERDQVGNILIRQPATAGMENRKPVVLQAHLDMVPQKNNDTVHDFTKDPIQPYIDGEW
                     VKARGTTLGADNGIGMASALAVLADENVVHGPLEVLLTMTEEAGMDGAFGLQSNWLQAD
                     ILINTDSEEEGEIYMGCAGGIDFTSNLHLDREAVPAGFETFKLTLKGLKGGHSGGEIHV
                     GLGNANKLLVRFLAGHAEELDLRLIDFNGGTLRNAIPREAFATIAVAADKVDALKSLVN
                     TYQEILKNELAEKEKNLALLLDSVANDKAALIAKSRDTFIRLLNATPNGVIRNSDVAKG
                     VVETSLNVGVVTMTDNNVEIHCLIRSLIDSGKDYVVSMLDSLGKLAGAKTEAKGAYPGW
                     QPDANSPVMHLVRETYQRLFNKTPNIQIIHAGLECGLFKKPYPEMDMVSIGPTITGPHS
                     PDEQVHIESVGHYWTLLTELLKEIPAK"
                     /name="pepD"
     gene            complement(17943..18503)
                     /gene="prfH"
                     /locus_tag="AOT98_RS25995"
                     /old_locus_tag="AOT98_26065"
                     /pseudo=""
     CDS             complement(17943..18503)
                     /gene="prfH"
                     /locus_tag="AOT98_RS25995"
                     /old_locus_tag="AOT98_26065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602105.1"
                     /GO_function="GO:0003747 - translation release factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006415 - translational termination
                     [Evidence IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor H"
                     /name="prfH"
     gene            complement(<18618..19660)
                     /locus_tag="AOT98_RS26000"
                     /old_locus_tag="AOT98_26070"
                     /pseudo=""
     CDS             complement(<18618..19660)
                     /locus_tag="AOT98_RS26000"
                     /old_locus_tag="AOT98_26070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706235.2"
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0006415 - translational termination
                     [Evidence IEA]"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="RNA ligase RtcB family protein"
                     /name="RNA ligase RtcB family protein"
     gene            complement(19906..20358)
                     /locus_tag="AOT98_RS26005"
                     /old_locus_tag="AOT98_26075"
     CDS             complement(19906..20358)
                     /locus_tag="AOT98_RS26005"
                     /old_locus_tag="AOT98_26075"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_001059860.1"
                     /translation="MNNIQIRDYQPGDFQQLCAIFIRAVTMTVSQHYSLQQIAAWAQID
                     ESRWKEKLAKSQVRVAVINAKLVGFITCVEHYIDMLFVDPEYTRRGVASALLKPFIKSE
                     SELTVDASITAKPFFERYGFQTVKQQRVECRGAWFINFYMRYKPQH"
                     /name="GNAT family N-acetyltransferase"
     gene            complement(20368..20766)
                     /gene="yafO"
                     /locus_tag="AOT98_RS26010"
                     /old_locus_tag="AOT98_26080"
     CDS             complement(20368..20766)
                     /gene="yafO"
                     /locus_tag="AOT98_RS26010"
                     /old_locus_tag="AOT98_26080"
                     /EC_number="3.1.26.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system mRNA interferase
                     toxin YafO"
                     /protein_id="WP_001263491.1"
                     /translation="MRVFKTKLIRLQLTAEELDALTADFISYKRDGVLPDIFGRDALYD
                     DSFTWPLIKFERVAHIHLANVNNPFPPQLRQFSRTNDEAHLVYCQGAFDEQAWLLIAIL
                     KPEPHKLARDNNQMHKIGKMAEAFRMRF"
                     /name="yafO"
     gene            complement(20776..21061)
                     /gene="yafN"
                     /locus_tag="AOT98_RS26015"
                     /old_locus_tag="AOT98_26085"
                     /pseudo=""
     CDS             complement(20776..21061)
                     /gene="yafN"
                     /locus_tag="AOT98_RS26015"
                     /old_locus_tag="AOT98_26085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706232.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system antitoxin YafN"
                     /name="yafN"
     gene            complement(21113..22167)
                     /gene="dinB"
                     /locus_tag="AOT98_RS26020"
                     /old_locus_tag="AOT98_26090"
                     /pseudo=""
     CDS             complement(21113..22167)
                     /gene="dinB"
                     /locus_tag="AOT98_RS26020"
                     /old_locus_tag="AOT98_26090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706231.1"
                     /GO_function="GO:0003684 - damaged DNA binding [Evidence
                     IEA]; GO:0003887 - DNA-directed DNA polymerase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /name="dinB"
     gene            complement(22238..23020)
                     /gene="lafU"
                     /locus_tag="AOT98_RS26025"
                     /old_locus_tag="AOT98_26095"
                     /pseudo=""
     CDS             complement(22238..23020)
                     /gene="lafU"
                     /locus_tag="AOT98_RS26025"
                     /old_locus_tag="AOT98_26095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706230.2"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="putative lateral flagellar export/assembly
                     protein LafU"
                     /name="lafU"
     gene            <22992..>24418
                     /locus_tag="AOT98_RS26030"
                     /old_locus_tag="AOT98_26100"
                     /pseudo=""
     CDS             <22992..>24418
                     /locus_tag="AOT98_RS26030"
                     /old_locus_tag="AOT98_26100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140833.1"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhA"
                     /name="flagellar biosynthesis protein FlhA"
ORIGIN
        1 gcgttaacct gttccattgt ggtgatcccg ttttcccgga aagccagaac ccactggcgg
       61 cggatttcgt tcagttcgtt ctggtcacgg ttagccagac tcgccgggaa agttgccagt
      121 aactggctga acacaccgtt gatgatctgc gctacctgct gtatctgcgg cttttcgtcg
      181 tactgttccg gcatgttgtt ggcgatccga cgcatctgct cacggtcaaa gttaaccatc
      241 tgtgcggcga tgtttttcat agatccaccc gtaaatccag tctgtgtttg tcaggtcgag
      301 ttttggtttg ctggctgtca cgactgcctg ttgcttgtta cggttgattt cgagctgggt
      361 ccacttgtcg cggagtttgg ccgggctaag cacgttaccg gaccagaagt tgtcctggca
      421 tgcccagcgg aacagtacac acatgtcgcg atggttacgt ccgtcacgtt cacgcatcag
      481 gcggatatcg ttagcccacc cagcaaaatt cggttttctg gctgatggtg cgatagtctt
      541 caccatgtca aacatccact ctgcggcggt caggtcttct gctgtccccc acttgctgcc
      601 gctctgaatt gcagcatccg gtttaaccac agaaagatcg ttttctggct ggtcagagga
      661 ttcgccagaa ttctcggacg aataatcttt tcttttttct tttgtaatag tgtcttttgt
      721 gtccacctgt tttgagggat agcaatcccc caatttgagg gatgttttat ccctcgtttt
      781 aggggatttt ccctcgtttt gagggataca ccattctgag atgtttttta tttggtccaa
      841 acatgccgcc ttgctgcttg ataatattca ttctgacgag ttctaacttg gcttcattgc
      901 accgtttgac aggtaacttt gtaatctcgc taagttgaga atcggtgatt ctgtccattg
      961 gtttattcca cccataggtt ttacgcagaa tggcaagcag cactttaaac tgtcgcttgg
     1021 tcagatctgc gcctgaataa gcctcaagca gcatatttga tagtctggcg taaccatcat
     1081 cgatatcagc cactcttcgc tcctgttcgg caaagttacc tctgccgaag ttgagtattt
     1141 ttgctgtatt tgtcataatg actcctgtgg attgatccag tctttctaca tcaggcctcg
     1201 aagaattcgc cgttcttcgg ggctttttct tttgtcaggt aatcggcaag ccgcttagtc
     1261 aattcagcca tttcatcgtc ttcgattccg tattccagaa cagcaagcat catgcttacc
     1321 tgcgagaaga aaccattctt ccatcggctt acctgatatt caggaacccc cattgctcga
     1381 gcgaatgtct tctgccccat cagtgccagt ttgttcagca aggccgactc gatgcgagcc
     1441 gctttcttgc ttttagttgc aatagtaccc atagataatt tccttaatga ttagatagag
     1501 ttggcttcgc aaagaaacgc aaaaccatag agatttgttt ctggtaatgc cctttttcag
     1561 ggcggtgatg tgtaagagcg agaatgtctt aagcggcttt accgcgttta gttccgtact
     1621 gtaaccaaac cggatcacag ttaagcgcca tagctatctc aaacaagaag cgcggtcgct
     1681 tggttactcc agcttcaatc agttgaattg attgctgttt aacaccggct ttggttgcca
     1741 gttcggtttg cgtcattttt aacgcaattc gcctcttctt gaggcgttca gaaagagttt
     1801 gcatatcgcc tccatcaaca aactttcttg tattttcata caatgtatct tgtttgtcaa
     1861 atacagtttt tcttgtgaag attggaggta aataacagag gtggcttatg agtatttctt
     1921 ccagggtaaa aagcaaaaga attcagcttg gacttaacca ggctgaactt gctcaaaagg
     1981 tggggactac ccagcagtct atagagcagc tcgaaaacgg taaaactaag cgaccacgct
     2041 ttttaccaga acttgcgtca gctcttggcg taagtgttga ctggctgctc aatggcacct
     2101 ctgattcgaa tgttagattt gttgggcacg ttgagcccaa agggaaatat ccattgatta
     2161 gcatggttag agctggttcg tggtgtgaag cttgtgaacc ctacgatatc aaggacattg
     2221 atgaatggta tgacagtgac gttaacttat taggcgatgg attctggctg aaggttgaag
     2281 gtgattccat gacctcacct gtaggtcaaa gcatccctga aggtcatatg gtgttagtag
     2341 atactggacg cgagccagtg aatggaagcc ttgttgtagc caaactgact gacgcgaacg
     2401 aagcaacatt caagaaactg gttatagatg gcggtcagaa gtacctgaaa ggcctgaatc
     2461 cttcatggcc tatgactcct atcaacggga actgcaagat tatcggtgtt gtcgtggaag
     2521 cgagggtaaa attcgtatga tcaggattgc ggcgctactc tcaatactct taactaccag
     2581 cgccaattct gaatgctgga ttgtcacaaa cctgcacggg tacggggcaa tgaatggcga
     2641 tcgttacgag tttacaaaag acagcacgga agattccgtt tttcacgtaa caataaatgg
     2701 cgataaatca tcagtttatg aatcagtttc tggcgtctat ccagagatga aatacactgc
     2761 tttgtcatcg aacactatgg taggagaata ccagtctgga ggaggaataa ccgttgaaac
     2821 ctggtcaatc actacagaca aaaaagctct ttactccaaa gtaatgaaca tcccaggtat
     2881 gcaacaactt acatcaacca aatcctttgt tggtgatgta gtcggaacct gcaaccagta
     2941 atcctcacct caatttcgac aaccaaaaaa caaactattt tccgtttaaa aacaatggag
     3001 tttgtttttc acgcccattt ttacaatatt tcttgtttac aacatacaat ctttcttgta
     3061 attttaagcc atcagcagga cgcactaacc accattgaag gtgaggctct taaaaattta
     3121 gccctgaaga agggcagcat tcaaagcaga aagctttgag tagcgcgaaa tgcagctgca
     3181 agacagcaac cgtggagata agcatcacgg cgcgttactc aaagctaact gacaggagaa
     3241 tccagatgga tgcacaaaca cgccgccgcg aacgtcgcgc agagaaacag gctcaatgga
     3301 aagcagcaaa tcccctgttg gttggggtaa gcgcaaagcc agttaaccgc cctattctct
     3361 cgctgaatcg caaaccgaaa tcacgagtag aaagcgcact gaatccgata gaccttacag
     3421 tgctggctga ataccacgaa cagattgaaa gcaacctgca acgtattgag cgcaagaatc
     3481 agcgcacatg gtacagcaag ccacgcagtg aaatgggtgt gacttgtgtt ggtcgccaga
     3541 aaatgaaatt aggcagcaaa ccacttattt gagaggaatt aatatgtcat caatccgctt
     3601 aactacgaga atgaaagagg aaatcgctcg taacgcttta attaagtctg gggttttcac
     3661 tgaacttgaa gaagtaacaa agttaaagaa ccagcttgca cttgacgcca gagttattgc
     3721 gtttggcggt aaaaagaaaa ctgaggaagt ggatcagtta tcatccaagt tggtagctat
     3781 aagtgaagaa cttggaaaga tgggatgttc attttactca tacgatgttc gttctacttc
     3841 aatttatctt actgtatctg gcagaagggt tggatggctt ccatatggga aagacggcaa
     3901 cggcgaagat atattgctcc ctactccgaa caaagataaa tgcatgttta gcgcagaaca
     3961 cgaaataaca aaaaggtttg atgaaatctg cgcattgcaa caaaaacttg aagccaagaa
     4021 aaaggatatc gaatcaaatg tatgggctgc tttgaactca gtcacaacag ttaagcgact
     4081 tattgaagtt tggcctgaaa gcaaagaatt gctaccaaaa gaagcagata aagcaagtac
     4141 agcacttcct gctttacggg tagaagattt gaataagatg attggacttc cttccgaggc
     4201 cgcatagtcg gcctttattt ttggcactaa caacagaata aacactgcac tgtgtattca
     4261 ttccaacgag tgaatacacg gagcaatgtc gctcgtaact aaacaggagc cgacttgttc
     4321 tgattattgg aaatcttctt tgccctctaa tgtgagggcc tttttatatg cataccaata
     4381 acgcttcact cgaggcgttt ttcgttatgt ataaataagg agcacaccat gcaatatgcc
     4441 attgcagggt ggcctgttgc tggctgccct tccgaatctt tacttgaacg aatcacccgt
     4501 aaattacgtg acggatggaa acgccttatc gacatactta atcagccagg agtcccaaaa
     4561 aatggatcaa acacttatgg ctatccagac taaattcact atcgccactt ttattggcga
     4621 tgaaaagatg tttcgtgagg ccgtcgacgc ttataaaaaa tggatattaa tactgaaact
     4681 gagatcaagc aaaagcattc actaaccccc tttcctgttt tcctaatcag cccggcattt
     4741 cgcgggcgat attttcacag ctatttcagg agttcagcca tgaacgctta ttacattcag
     4801 gatcgtattg aggctcagag ctgggcgcgt cactaccagc agatcgcccg tgaagagaaa
     4861 gaggcagaac tggcagacga catggaaaaa ggcctgcccc agcacctgtt tgaatcgcta
     4921 tgcatcgatc atttgcaacg ccacggggcc agcaaaaaag ccattacccg tgcgtttgat
     4981 gacgatgttg agtttcagga gcgcatggca gaacacatcc ggtacatggt tgaaactatt
     5041 gcccgccacc aggttgatat tgattcagag gtataaaacg gatgagtaca gcactcgcaa
     5101 cgctggcagg gaagctggct gaacgtgtcg gcatggattc tgtcgaccca caggaactga
     5161 tcaccactct tcgccagacg gcatttaaag gtgatgccag cgatgcgcag ttcatcgcat
     5221 tgttgatcgt cgccaaccag tacggcctta atccgtggac gaaagaaatt tacgccttcc
     5281 ctgataagca gaacggcatc gttccggtgg tgggcgttga tggctggtcc cgcatcatca
     5341 atgaaaacca gcagtttgat ggtatggact ttgagcagga caatgaatcc tgcacatgcc
     5401 ggatttaccg caaggaccgc aatcatccga tctgcgttac cgagtggatg gatgaatgcc
     5461 gccgcgaacc attcaaaacc cgcgaaggca gagaaatcac ggggccgtgg cagtcgcatc
     5521 ccaaacggat gttacggcat aaagccatga ttcagtgtgc ccgtctggcc ttcggatttg
     5581 ctggtatcta tgacaaggat gaagccgagc gcattgtcga aaataccgca tacactgcag
     5641 aacgtcagcc ggaacgcgac atcactccgg ttaacgatga aaccatgcag gagattaaca
     5701 ctctgctgat tgccctggat aaaacatggg atgacgactt attgccgctc tgttcccaga
     5761 tatttcgccg cgacattcgc gcatcgtcag aactgacaca ggccgaagca gtgaaagctc
     5821 ttggattcct gaaacagaaa gcctctgaac agaaggtggc tgcatgacac cggacattat
     5881 actgcagcgt accgggatcg acgtgagagc tgtcgaacag ggggatgatg cgtggcacaa
     5941 attacggctc ggcgtcatca ccgcttcaga agttcacaat gtgatagcaa aaccccgctc
     6001 cggaaagaaa tggcctgaca tgaaaatgtc ctacttccac accctgcttg ccgaggtttg
     6061 caccggtgtg gctccggaag ttaacgctaa ggcgctggcc tggggaaaac agtacgagaa
     6121 cgacgccaga gtcctgtttg agtttacttc cggcgtgaat gttactgaat ccccgatcat
     6181 ctatcgcgac gaaagtatgc gcaccgcctg ctctcccgat ggtttatgca gtgacggcaa
     6241 tggccttgag ctgaaatgcc cgtttacctc ccgggatttc atgaagttcc ggctcggtgg
     6301 tttcgaggcc ataaagtcgg cttacatggc ccaggtgcag tacagcatgt gggtgacacg
     6361 aaaagatgcc tggtactttg ccaactatga cccgcgcatg aagcgtgaag gcctgcatta
     6421 tgtcgtggtt gagcgggatg aaaattacat ggcgagtttt gacgagatgg tgccggagtt
     6481 catcgaaaaa atggacgagg cactggctga aattggtttt gtatttgggg agcaatggcg
     6541 atgaagcatc ctcacgataa tatccgggta ggcgcgatca ctttcgtcta ctccgttaca
     6601 aagcgaggct gggtatttcc cggtctttct gttatccgaa atccactgaa agcacagcgg
     6661 ctggctgaag agataaataa taaacgaggg gctgtatgca caaagcatct cctgttgaat
     6721 taagaacgag tatcgagatg gcacatagcc tcgctcaaat tggagtcagg tttgtgccaa
     6781 taccagtaga aacagacgaa gaatttcata cgttagccgc atccctttca caaaagctgg
     6841 aaatgatggc ggcgaaagca gaagcaaacg agagagaccc ggcatgacaa caacagaatg
     6901 catttttctg gcagcgggct tcatattctg tgtgcttatg cttgccgaca tgggacttgt
     6961 tcaatgacac ctcagcaaga aaacgccctt cgcagcattg cccgtcaggc taattctgaa
     7021 atcaaaaatg ccagacagca gtttccggat aaaaacgtcg atgacatttg ccgtagcgta
     7081 ctgaagaagc accgcgaaac ggtagcgctg atgggattca caccgactca tttaagcctg
     7141 gcgatcggca tgttaaacgg cgtctttaag gaacggtgaa catgaaaagc aaaatcatca
     7201 gggagctaca ggctcctttt ttattgttcg cattcaccct caagcgtatt aaccaacaat
     7261 tcagggatta atgaaagatg gcagacatca ttgattcagc atcagaaatc gaagaattac
     7321 agcgcaatac agcaataaaa atgcgtcgtc tgaaccacca ggctatatct gccactcatt
     7381 gttgtgagtg tggcgatccg atagatgaac taagacgtct ggccgttcag ggttgtcgga
     7441 cttgtgcaag ttgccaggag gagatcgaac ttaagaacaa acaatgggga ttgtgatggc
     7501 ctcaaagcag caaatttcaa catcgtccaa ctgaggtgta aaaatgttca gaatcatttt
     7561 tcctaacacc tggtacgtcg accaccacgg cactccctgc aaaatcctgc gttctaccca
     7621 caacaaagtt cactacatcc gaaaaggcag aacatgtatc gccagcatgt tccgctttaa
     7681 tcatgacttt gaacctgtga ataaagctga tgcagatcgg atagcagaag agatcgaaac
     7741 ggcagaacac attaagaagt tacgtgacat gcgttcaaaa agcagaggta accatggaat
     7801 catacagcct cacactcgat gaggcctgtc agtttctcaa gatatccaga cctaccgcta
     7861 ccaactggat acgaacaggc cgcctacagg caacacgcaa agaccccact aaaccaaaat
     7921 ctccttacct cacaacgcga caagcctgca ttgcggcgct tcagtctccg ctgcatacta
     7981 tcaaggtgag cgcgggtgat ggcataacag aggaaagaaa atgtcactct tccgcagagg
     8041 tgaaatatgg tacgccagtt tcacattgcc gaacggtaaa agatttaaac agtctcttgg
     8101 aacaaaggac aaaaggcagg cgacagaact ccatgacaag ctaaaggctg aagcatggcg
     8161 ggtcagcaaa cttggtgaaa tacctgatat aacgttcgag gaagcgtgtg tcaggtggct
     8221 tgaagagaaa gcacataaaa aatcactgga cgatgacaaa agccggatcg gattctggct
     8281 tcaacatttc gcaggaatgc aactaagaga cattactgaa tcaaaaattt attcagcaat
     8341 gcagaaaatg acgaaccggc gtcatgagga aaactggaaa ctcagggcag aagcatgcag
     8401 aaaaaaaggg aaacctgttc cagaatacac gccaaaacca gcgtccgttg caacgaaggc
     8461 tacgcatctt tcatttataa aggccctgct aagagccgca gagcgtgaat ggaaaatgct
     8521 ggataaggca ccaattatta aagtgcctca accaaagaat aaacggatcc gctggctgga
     8581 gccccatgaa gcacaaaggc tgattgatga atgtccggag ccattaaagt ctgttgttga
     8641 atttgcactg gcaacaggct taagacgctc gaacatcatc aaccttgaat ggcaacaaat
     8701 agatatgcag cgccgggtgg catggataaa cccggaagag agtaaatcaa accgcgcaat
     8761 tggcgttgcg ctgaatgata ctgcatgtcg cgtattgaaa aaacaaatcg gtaatcatca
     8821 ccgttgggta tttgtgtaca aggaaagctg taccaaacca gacggaacga aagcgccaac
     8881 agtaaggaag atgcggtatg acgcaaacac agcctggaaa gcggctctga gacgggctgg
     8941 tattgatgat ttcagatttc acgacttgag acacacctgg gcaagttggc tggttcaagc
     9001 cggagtcccg ttgtcagtgt tacaggaaat gggaggctgg gagtctatcg aaatggttcg
     9061 tcgatatgct caccttgcac ctaatcacct taccgaacac gcacggcaaa tagactcgat
     9121 cctgaaccca tcggtcccaa atttgtccca gtcaaaaaat aaggaaggta ctaatgatgt
     9181 gtaacttatt gatttaaatg gtgccgataa taggagtcga acctacgacc ttcgcattac
     9241 gaatgcgctg ctctaccaac tgagctatat cggccctgaa aggacatgtt cacgaacgtg
     9301 aatcacggtg gacaaggtta aaactaaccg ggcgatgcgt caatggcctt gtgaatcaaa
     9361 tggctacttt tgcatcaccc ggttttattt acgcacgaat ggtgtaatca ccaatgccga
     9421 tccacttgta agtggtcagt gcttccagcc ccattgggcc acgcgcgtgg agtttttgtg
     9481 tgcttaccgc cacttccgca cccagaccaa actggccgcc gtcggtaaaa cgcgtagagg
     9541 cgttaacgta aacagcggac gaatccactt cgttaacaaa acgctgggcg ttgcgcatat
     9601 cgcgggtcag gatcgcatcg gagtgttgtg tgccgtgttc acgaatatgg gcgatggcat
     9661 cgtcaagatc gctgacgatt ttgacgttca aatctaatga cagaaactca tcgtcatact
     9721 cttcggcttt aaccgccacc accttcgcag ggcctgcctg caactgtgtc agcgcagctg
     9781 catctgcgtg taatgtcacg ccgctttccg ccatttgttt gcttaatgcg ggcaggaagc
     9841 tatcggcgat gtttttattc accagcaacg tttcaaccgt attacatgtg ctcggacgct
     9901 gagttttcgc gttgacgatc acttttaatg cttcagcgat ctctgcactt tcatcaacgt
     9961 aaatatggca tacgcctata ccacctgtga tcaccgggat tgtcgactgt tcacggcaca
    10021 gtttatgcaa accagcgcca ccacgcggga tcagcatgtc gatgtattta tccatacgca
    10081 gcatttcact gaccagcgca cggtcaggat tatcaatcgc ctgcacggca cccgccggta
    10141 agccacagga tttcagggcg tcctgaatca ccgccaccgt tgccgcgtta gtgcgacagg
    10201 tttctttacc accacgcagg atcaccgcat taccggtttt caggcacagc gaagcgacat
    10261 caaccgtcac gttcgggcgc gcttcataaa tcacgccaat aacccccagc ggtacgcgac
    10321 gacgctcaag acgcaggccg ctgtccagta cgccgccatc gattacctgc cccaccggat
    10381 cggcgaggtt gcacacctga cgtacatcgt cggcaatgcc tttcagccgt gcgggcgtca
    10441 gtgccagacg gtcaagcatc gcttcgctaa ggccattggc tcgcgcgtca gcaacatcct
    10501 gggcgttagc gttgaggatg atttcgcttt gtgcttccag ttcatcggcg attttttcca
    10561 gcacgcgatt tttttcgcgg ctggagagtt gcgctaattt atacgaggct tgcttcgcgg
    10621 caatgcccat ttgttccagc atcggccagc tccttaacgg gtaatcatgt catcacggtg
    10681 aacggcaacc gggccgtatt catatcccag tattgcatca atttcttgcg agtggtgtcc
    10741 ggcaatacgg cgtaatgcat cgctgttgta acgactgaca ccgtgggcga tatcgcgacc
    10801 ttcgaggttg caaatgcgga tgacttcacc acgcgagaaa ttgccagtca cgcttttaat
    10861 gcctttcggc aacagggagc tgccgcgttc cagaatggcg gcagttgccc cttcatctac
    10921 cgtgatttca cccgccggcg gcgcaccgaa aatccagcgt ttacggtttt caagcggagt
    10981 cgcctgggca tggaacagcg taccgacgga aatgccttcc atcacatcac caataacgcc
    11041 cggcttgctg cccgcggcaa taatggtgtc gatacccgca cggcaagcca cgtcagcggc
    11101 ctgcaattta gtactcatgc cgccagttcc gaggcctgaa acgctgtcac cggcaatcgc
    11161 gcgcagtgcg tcatcaatgc cgtaaacatc tttaatcagt tctgcctgcg gatttctgcg
    11221 cggatcagcg gtatacaaac ctttttgatc ggtcagcagc aacagtttat cggcacccgc
    11281 cagaatcgcc gccagcgcag aaaggttatc gttatcgccg accttaatct ctgccgtagc
    11341 gacagcatcg ttctcattga ttaccggaac gatattgtta tcgagcaacg cacgcagggt
    11401 gtcgcgggcg ttcaggaagc gttcacggtc ttccatatca gcacgggtca gcagcatttg
    11461 cccgacgtga atgccataaa tcgaaaacag ctgttcccac agttgaatca gtcgactctg
    11521 ccctaccgcc gccagcagtt gtttcgaggc gatagtcgct ggcagttccg ggtaacccag
    11581 gtgctcacgt ccggcggcga tcgcgcccga cgtcacaata acaatccgat gcccggcggc
    11641 atgtaactgc gcgcactggc gaacaagttc aacgatatgg gcacggttca gacggcgcga
    11701 tccgcctgtt agcacactgg tgccgagttt taccaccagc gtctggctgt cactcatgat
    11761 tctctgccat tcaattttag gaaaaatgat atcaaacgaa cgttttagca ggactgtcgt
    11821 cggttgccaa ccatctgcga gcaaagcatg gcgttttgtt gcgcgggatc agcaagcgta
    11881 gcggcagttg tttacgcttt tattacagat ttaataaatt accacatttt caggtaatga
    11941 ctccaactta ctgatagtgt tttatgttca gataatgccc gatgaccttg tcatgcagct
    12001 ccaccgattt tgagaacgac agtgacttcc gtcccagcct tgccagatgt tgtctcagat
    12061 tcagattatg tcgctcaatg cgctgagtgt aacgcttgct gataacgtgc agctttccct
    12121 tcaggcgtga ttcatacagc ggccagccat ccgtcatcca taccacgacc tcaaaggccg
    12181 acagcaggct cagaagacgc tccagtgtgg ccagagtgcg ttcaccgaag acgtgcgcca
    12241 caaccgtcct ccgtatcctg tcatacgcgt aaaacagcca gcgctgacgt gatttagcac
    12301 cgacgtagcc ccaatgttcg tccatttcag cgcagacaat cacatcactg cccggttgta
    12361 tgcgcgaggt taccgactgc ggcctgagtt ttttaagtga cgtaaaaccg tgttgaggcc
    12421 aacgcccata atgcgtgcac tggcgcgaca tccgacgcca ttcatggcca tatcaatgat
    12481 tttctggtgc gtaccgggct gagaggcggt gtaagtgaac tgtagttgcc atgttttacg
    12541 gcaatgagag cagagatagc gctgatgtcc ggcagtgctt ttgccgttac gcaccacgcc
    12601 ttcagtagcg gagcaggaag gacatctgat ggaaatggaa gccacgcaag caccttaaaa
    12661 tcaccatcat acactaaatc agtaagttgg cagcattacc cattttcaga atatcattaa
    12721 tctgtaatat atctttaaca atctcaggtt aaaaactttc ctgttttcaa cggggctctc
    12781 ccgctgaata ttcgcgcgtt aattaaaatc aggaatgaaa atgaaaaaga gcactctggc
    12841 attagtggtg atgggcattg tggcatctgc atctgtacag gctgcagaaa tatataataa
    12901 agacggtaat aaactggatg tctatggcaa agttaaagcc atgcattata tgagtgataa
    12961 cgccagtaaa gatggcgacc agagttatat ccgttttggt tttaaaggtg aaactcaaat
    13021 taacgatcaa ctgactggtt atggtcggtg ggaagcggag tttgccggaa ataaagcgga
    13081 gagtgatact gcacagcaaa aaacgcgtct cgcttttgcc gggttgaaat ataaagattt
    13141 gggttctttc gattatggtc gtaacctggg cgcgttgtat gacgtggaag cctggaccga
    13201 tatgttcccg gaatttggtg gcgattcctc ggcgcagacc gacaacttta tgaccaaacg
    13261 cgccagcggt ctggcgacgt atcggaacac cgacttcttc ggcgttatcg atggcctgaa
    13321 cttaaccctg caatatcaag ggaaaaacga aaaccgcgac gttaaaaagc aaaacggcga
    13381 tggcttcggc acgtcattga catatgactt tggcggcagc gatttcgcca ttagtggggc
    13441 ctataccaac tcagatcgca ccaacgagca gaacctgcaa agccgtggca caggcaagcg
    13501 tgcagaagca tgggcaacag gtctgaaata cgatgccaat aatatttatc tggcaacttt
    13561 ctattctgaa acacgcaaaa tgacgccaat aactggcggc tttgccaata agacacagaa
    13621 ctttgaagcg gtcgctcaat accagtttga ctttggtctg cgtccatcgc tgggttatgt
    13681 cttatcgaaa gggaaagata ttgagggcat cggtgatgaa gatctggtca attatatcga
    13741 cgtcggtgct acgtattatt tcaacaaaaa tatgtcagcg tttgttgatt ataaaatcaa
    13801 ccaactggat agcgataata agctgaatat taataatgat gatactgtcg cggttgggat
    13861 gacgtatcag ttttaatgaa tattgccgga tgtgatgcat ccggcacatt tcactcacgc
    13921 cgttaacttc accggttcat cacgaaaatc attcgccggt tccagcttca gattcagcgt
    13981 cgtcagcagt tcacgcagct tctcgtgaaa ctcacgcagg gtgtgctcca gtcgttcaac
    14041 cacttcagta tcttttaccg gaacactctt ccagtcgcct gctttatcga acagaccaaa
    14101 ctggtagctg taggtaaaac gggattcctg cgcttccagc tccatccacc agccccagaa
    14161 ttcacgcact tccggtgccg gtttcacgtt gacgcataca gccagacaat cgaaaaagaa
    14221 tcgattatct tcgcacttac cttcacgaat atacgggcct agtgcggtaa attttttgat
    14281 caatctgctc ttcgggtgtc cactcggtaa cgtcattgct atctcctgtt gtgatgcaac
    14341 tgttttacca aattggcaaa atttagcaaa tttttaacac aagcgttttt cgatccagcc
    14401 ggtgatttcc tgaagacctt tgtcaaaatt ccgatacacc gggttaaatg ggatctctaa
    14461 taatttaccg tcagcagatg atgaggtgat taagcgtgag tcctcttccg ggctgaacgg
    14521 atcgttcttc cagtagcctg ataacattgg cgttgggcag cgacgcccca gcaatccttg
    14581 cacttttaat gaatagcgat tcagctccac gcgtaacgct tcgtcggaag catcatgcat
    14641 ccccaaacga ctcgccagaa cgtcaagata catttccggc acctgttgct ggcacttaaa
    14701 atcactcaac agggtatgaa ctaccggacc aagacaggca accgctttca gacgcggcga
    14761 ttcaaggtat gccagacgca cggcaacgtt agcgccgaaa cggaaaccaa aggccgcgac
    14821 gcgagtgtga tccacccacg gtacgttagg cagcgccttt aagacgtgct gatgcaacag
    14881 gctggagtcc tgggtgagct tccattttga agaaaagccc accgacggca tatcaatagt
    14941 cagcatcgca atgccgcgcg gcgcaaaata acgttcatac aggctgtaat agtccgtctg
    15001 catcgcatcc agaccaccac acattaatac tgtcgggaac gggccatcgc ctttcggcat
    15061 atgcaaaaag ccggtgatgg gcgcaccgcc gggtacggta aactccatct gccgcatcgt
    15121 gcccggcaga cgctgggcgg cctcttcata ggcgcggttt gataaagcct gcgcttgctc
    15181 ggccaggtca tctcctttca gatgaggata ggcggcaatg ttgtacaacg tagccgcatg
    15241 cagccagtgt cgaccactga gttgcggatc ttcttccgta caggcttttt gttgccacac
    15301 catcgcctgg gtggcccact cataaatcca gttgccacca cggtagccaa tcacggtatc
    15361 gtataaatca tcgtcggtac gttcagcatc gctcatcaca atacgtgcct ggacgtcgag
    15421 gatttcacgt gggtcaatac cgcgccagat ccacatcaga cggttaatca tgcgatacca
    15481 gtgagggatg gttttaccat caagagccga ctgcacaggc ggttgtgcgc cgtgattaaa
    15541 gcggcggact agcgtcgagg tttcaggatg tttaaagcgg ggtttgaaca gggtttcgct
    15601 caggtttgcc tgtgtcatgg atgcagcctc cagaatactt actggaaact attgtaacct
    15661 gcctgaagtt aaaaagaaca acgcccggca atgccaggcg ttgaaaagat tagcgaccgg
    15721 agattggcgg gacgaatacg acgcccatat cccacggctg ttcgatccag gtatcttgcg
    15781 ggatatcaac aacatagtca tcaaccagcg gacgaccagc cggttttgcg aagatggtga
    15841 caaagtgcgc ttttggatac atttcacgaa tcgcaacagc agtaccaccg gtatccacca
    15901 ggtcatcaat aacgatgaag ccttcgccat cgccttctgc gcgtttcagc actttaagct
    15961 cgcgctggtt gtcgtgatcg tagctggaaa tacaaacggt atcgacatga cgaataccca
    16021 gttcacgcgc cagtaacgcc ccggtaccag accgccacgg cttacggcaa taatgccttt
    16081 ccattgttca gaaggcatca gtcggcttgc gagtttacgt gcatggatct gcaacatgtc
    16141 ccaggtgacg atgtattttt cgctcatgtg aagtgtccca gcctgtttat ctacggctta
    16201 aaaagtgttc gaggggaaaa taggttgcgc gagattatag agatctggcg cactaaaaac
    16261 cagtatttca catgagtccg cgtcttttta cgcactgcct ctccctgacg cgggataaag
    16321 tggtattctc aatacatatc tcgcaagcct gtcttgtgtt gacaacattt tctgctaacc
    16381 ctgtgacctg caatactgtt ttgcgggtga tcgacaagga gacttaacgt gtctgaactg
    16441 tctcaattat ctccacagcc gctgtgggat atttttgcca aaatctgttc tattcctcac
    16501 ccgtcctatc atgaagagca actcgctgaa tacattgttg gttgggcaaa agagaaaggt
    16561 ttccatgtcg aacgcgatca ggtaggtaat atcctgattc gtcaacctgc taccgcaggt
    16621 atggaaaatc gtaaaccggt cgtcttacag gcccacctcg atatggtgcc gcagaaaaat
    16681 aacgacaccg tgcatgactt cacgaaagat cctatccagc cttatattga tggcgaatgg
    16741 gttaaagcgc gcggcaccac gctgggtgcg gataacggca ttggtatggc ctctgcactg
    16801 gcggttctgg ctgacgaaaa cgtggttcac ggcccgctgg aagtgctgct gaccatgacc
    16861 gaagaagccg gtatggacgg tgcgttcggc ttacagagca actggttgca ggctgatatt
    16921 ctgattaaca ccgactccga agaagaaggt gaaatctaca tgggttgtgc ggggggtatc
    16981 gacttcacct ccaacctgca tttagatcgt gaagcggttc cagctggttt tgaaaccttc
    17041 aagttaacct taaaaggtct gaaaggcggt cactccggcg gtgaaatcca cgttggcctg
    17101 ggtaatgcca acaaactgct ggtgcgcttc ctggcgggtc atgcagaaga actggacctg
    17161 cgccttatcg atttcaacgg cggcacactg cgtaacgcca tcccgcgtga agcctttgcg
    17221 accattgctg tcgcagctga taaagtcgac gcactgaaat ctctggtgaa tacctatcag
    17281 gagatcctga aaaacgagct ggcagagaaa gagaaaaatc tggccttgtt gctggactct
    17341 gtagcgaacg ataaagctgc cctgattgcg aaatctcgcg atacctttat tcgtctgctg
    17401 aacgccaccc cgaacggtgt gatccgcaat tccgacgtgg caaaaggtgt ggtcgaaacc
    17461 tccctgaacg tcggtgtggt gaccatgact gacaataacg tagaaattca ctgcctgatc
    17521 cgttcactaa tcgacagcgg taaagactac gtggtgagca tgctggattc gctgggtaaa
    17581 ctggctggcg cgaaaaccga agcgaaaggc gcatatcctg gctggcagcc ggacgctaat
    17641 tctccggtga tgcatctggt acgtgaaacc tatcagcgcc tgttcaacaa gacgccgaac
    17701 atccagatta tccacgcggg cctggaatgt ggtctgttca aaaaaccgta tccggaaatg
    17761 gacatggttt ctatcgggcc aactatcacc ggtccacact ctccggatga gcaagttcac
    17821 atcgaaagcg taggtcatta ctggacactg ctgactgaac tgctgaaaga aattccggcg
    17881 aagtaattat ttgatttgct gccggatggc gtttaatcgc cttccggcag tttcatcctt
    17941 cattatcctt cgataaaagc catccctgta aacgttcgtc gcgggttgcc acgttcaatc
    18001 tggtgatgga acattcgccg ctgtgatttc agcaccgcgc tattttccta ttgctgctga
    18061 tccagcttcc aggcaatcag caatcgcgcc agccgtttgt tagcatgctg gctgcgctct
    18121 gactgaacct tcacgctaat accggatgcc aaatgcgtgg cgcgtaccgc cgagtcggtt
    18181 ttattgacat gttgaccgcc cggccccgac gaacgcagcg tctcataccg gatcgcatcg
    18241 gattgctcct gctcatcagc ggtaaaacgc ccaatgccca gaaaccagtt tttacgcccg
    18301 tgatgtgggc gatacgggct cgggcaaatc cactgaatag tgccacacca gctttcgctt
    18361 aacgcccatg cgttgtcgcc atccagagaa atcagcgccg aacgcagcgt gtcagagtag
    18421 cggcctgttt ctgtttccag caccgttacc gcgacgtctt gtcgggcagc ttctttaatt
    18481 agcctgtcca gcgccttttt cactgcgaga caacattctt ccggcccctg cgctgaggag
    18541 agttatagca agatcatcct tttttccctc cactgttttt gagcgttagc accggacgca
    18601 gccgcgcgac aggaataatt aatccggcct gcctgacatt gcaccacact ttcagccgat
    18661 ttataggctt gtggcgcttc ttcgaagatg agttgtttat cgcgacaaat tacccgactg
    18721 ccaagttcag tacgcgagag ttgcgtcgct gtgtatttcg ctgccagacg ccctttacac
    18781 tcggtgcgcc cccatttacg cccagcccca tgcgccagcg aatgcaatgt ttcctcactc
    18841 ctgacgggct gaacagcctg gagtaatcac cgcgtgaacc gggaataacc accagaccac
    18901 agtcatcagg cgtggcacct ttacgatgta agaccccttg ttgatcaccg attcgacacg
    18961 cgctaacaaa gttatgcgcc acatccagaa ccggacttcc ggtggcctta acctgttgca
    19021 ttatgcgcaa agcgatcagg tggcgattaa aacgcgcaaa cgccagcgcg tcgtcactgc
    19081 cttcaggcaa accatgatgc gaaaacgagg caatatgccg ctgtaaaata gactgcccta
    19141 gccccctcga gccgctatga accagcagtt gcagatgctg cgcatccaga cctgccagtg
    19201 caaacagttc agcgttgatg atttgatcaa cttgttgcag ttcagcgaaa tgattgccac
    19261 caccgataga gccaagcgag ctgcgccacg gatgctgtgc aaatgctgac ggcaggtttt
    19321 cctccagcca gctttcttca gcaacgtcat ccaaagctga taatcgcttt tcaaacttat
    19381 cggcgttgta tttgcgagcg agaatatctg tttgccatag cgccatgcca cagccgatat
    19441 cattgccgac cagtgctggg taaaaacggc ctgcggagaa gaacgctgcg ccaatcgggt
    19501 agccgcgtcc ggggtgtaaa tctggcatcc ccactacgcg ctgcatgttg ggtaaatttg
    19561 ccgtggtgtg taattgttgg atcgctaaac tctcgatcca caggtcatca gatgcgatgg
    19621 taaataccgc atcggataag ggacgaatat aattgcccat ataccattcc gtaaatagac
    19681 tcgtcatact tcaagttgca tgtgctgcga cttgaattat tgagagtaac aattaaaaaa
    19741 tcaggaaatg gcagacgaat ccagggcaag aaaaaaagaa ttaatcctgg aaaggtctgc
    19801 aaagagtcat tgataaagga tttgtcatga tttacctcct tgcagtttgt ggaataagaa
    19861 aacgcgcaca tactaggcgg gcgttatttt cattgcaagc tggatttaat gttgcggttt
    19921 ataacgcata taaaaattaa taaaccacgc tccccggcat tcaacgcgct gctgcttaac
    19981 tgtctgaaaa ccataacgtt caaaaaaggg ttttgcggtt atgcttgcgt ccaccgtaag
    20041 ttcggattca gacttaataa aaggttttaa caaagcgctg gcaaccccac ggcgggtgta
    20101 ttcagggtca acaaataaca tatcgatata gtgttcaacg caggtaataa agccgaccag
    20161 ttttgcatta ataactgcaa cccgcacttg tgatttcgcg agtttctcct tccagcgaga
    20221 ttcgtcaatc tgcgcccagg cggcaatttg ttgtagtgaa taatgctgac tgacggtcat
    20281 cgtaaccgct ctaatgaaaa tagcgcatag ttgctgaaaa tcgccaggct gataatctct
    20341 tatttgtatg ttattcataa tataaattca aaaacgcatg cgaaacgctt ctgccatttt
    20401 tccaatttta tgcatttggt tgttatctcg agccagttta tgaggttcag gcttcagaat
    20461 ggcaatgagc aaccatgctt gctcatcaaa cgcaccctga caatatacca aatgcgcttc
    20521 gtcattcgtt ctgctgaatt ggcgcaactg tggcggaaat ggattattca catttgccag
    20581 atgaatatga gcaactcgct caaatttgat taatggccag gtaaacgagt cgtcgtagag
    20641 tgcatcgcga ccaaatatat ctggcaaaac accgtcacgc ttataggaaa taaaatccgc
    20701 cgttaacgca tcaagttcct ctgctgtaag ttgcaggcga ataagttttg ttttgaatac
    20761 ccgcatcctt attccttaaa agtcattgaa atcatcatcc gtcatatcat taagatattg
    20821 tttagcgcgg cgtgtaattt cctctaatct tgcagcactt ggacgaaagc gcgcctttat
    20881 gggctttttc tcctcttgtt cagcaagcat gtccattaac gcttcgaatg cgctggcact
    20941 taagagatat ctgcggggcg attattagaa agaaccgcaa ctggttgatc aataagtatt
    21001 tagctgggtt tttacgtaac tcagtgatat tgaccgattt ttcagcgaga attcgatgca
    21061 tacagtgata ccctcataat aatgcacacc agaatataca taatagtata catcataatc
    21121 ccagcaccag ttgtctttcc atttgcgggt caagcaacgt cacatgcagc cccaccagac
    21181 gcacaccgcg cccgccgcgg cgttcatccc aggttttacg cgcggtggcg attaagtcag
    21241 ctttattcag ccgcggccag acgtgctcct gggtggtctg ctgaaaatcg tcgaacttta
    21301 atttcacccc ctggcgagca atcagtaaat caggttttac ctttgccaga cggcgttcaa
    21361 gttccggata cagccgctcg ataatcgctt cacattcaga ccagtgatga atatcttccg
    21421 ccatcgtgcg ttccacgccg acggattttc gtaaccgttc gctgttaacg tcgcgctcgt
    21481 caatcccctg actacgctcc cacaaaatgc ggccaaattt gccaaagcgt ttaagcagaa
    21541 tcaccagatc acacttttgt acatcaccgc aggtccgcag cccatcgctt ccagttttgc
    21601 cgccgagact ttgccgacgc cggggatttt ttccagtggt aaggtttgta aaaatgccgg
    21661 aacttctgcc ggcgtaatca caaactgacc gttgggttta ttcatgtcgg aggcgatttt
    21721 ggcgagaaac tttactggtg ccacgcccgc agatgccgtc agttgcagct cgttgaagat
    21781 cgtctggcgg atttcctggg cgatgagggt cgcagaaccg tggcaatgga cgctatcggt
    21841 gacatcgaga taagcctcat ccagtgacaa cggttcaatg cgcgaggtgt agcgcgagaa
    21901 gatttcacgg atatgatttg aggcttcttt gtaggcgtca aagcgccccg gaagcaaggt
    21961 gagatgtggg cataatttga gcgccatccc agtaggcata gcgctacgta cgccaaattt
    22021 acgcgcggga taattggcgg tgctgatcac cccccgacgt tcgcggctgc cgccaatagc
    22081 aatagggata tcgcgcagag cgggattgtc gcgcatctcc accgctgcga aaaagcagtc
    22141 catatccaca tgaatgattt tacgcattgc tcacctctca acactggtaa agtatacagt
    22201 gatttcaggt tttgagaaat gcgtaaagat tcagcattta gcgcattcgc tgcgaaagca
    22261 cctgctgctt atccagcttt tgcaccagcg gctgcaccac tttatcccca tgctgaccaa
    22321 agtattgata cagcgtatcg gacgcacttt tggtcagcac cataatctca atacgccgat
    22381 tgcccgcgct ttgcggattc ttcgcgtcca gcagcatctg gtccgccatt gcgcttacct
    22441 gcatcacttt atcttccggc attccggcct cttccagcac ccgacgagct gaaagcgcgc
    22501 gatcgcccga aaggttccag ttgttgtaga tattgttttg taggccatcg catcggtatg
    22561 cccggtaata ataattttgt tatagagcga gtcgaacact ggcgcgagct ccaccagcaa
    22621 agttttaaag aacggcataa tctgcgcgct gccgcgttcg aacatattgc gattctggtc
    22681 gtctttaatc agcacgcgta atccctggga acaatctcca tctccagatt cgcttccata
    22741 tgcgcatcac gggcaatggt gttgatactg gttgccaact cgccaagctc ggtggcggat
    22801 ttcttcttca gcagcgccgt tttctcattc acatcacgcg cttttttctc cgtctcttcc
    22861 ggcaccgcca cggtggcagg ttttggcgga tgagacgggc tgattttatt taacggcgac
    22921 agcccaccac cgttaaaaat cgactgccgt gcagcgcggc gataatgctt tcacgctcgg
    22981 atttactgac gctgttgaca atcaacttta tcgtcgtcac caaagaggcc gagcgtattt
    23041 ccgaggtttc tgcccgcttt accctggacg cgatgcccgg caaacagatg gcgattgacg
    23101 ccgatcttaa cgccggattg atcaaccagg cgcaggcgca aacccggcgt aaagatgttg
    23161 ccagcgaggc cgatttctac ggcgcgatgg acggggcatc gaagtttgta cgcggagacg
    23221 ccatcgccgg gatgatgatt ctggcgatca acctgagcgg cggcgtctgt atcggcatct
    23281 tcaaatacaa cctgagcgcc gacgccgcct tccagcaata cgtgctgatg accatcggcg
    23341 acggcctggt ggcgcagatc ccttccctgc tgctctccac cgcggcggcg attatcgtca
    23401 cccgcgtcag cgacaacggc gatatcgccc atgacgtgcg ccaccagttg ctggcaagcc
    23461 cgtcggtgct ctacaccgcc accgggatca tgttcgtgct ggcggtggtg ccggggatgc
    23521 cgcatctgcc gtttttgctg ttcagcgccc tgcttggctt taccggctgg cggatgagca
    23581 aacgcccgca ggcggcggag gcggaagaga aaagcctcga aacgctgacc cgcaccatca
    23641 ctgaaaccag cgaacaacag gtcagttggg aaactattcc gctgatcgag cccatcagct
    23701 taagcctcgg ctacaagctg gtggcgctgg tggacaaagc gcagggcaac ccgctcaccc
    23761 agcggattcg cggcgttcgg caggtgattt ccgacggtaa cggcgtgctg ctgccggaga
    23821 tccgcattcg ggaaaacttc cgcctcaagc ccagccagta cgctattttc atcaacggca
    23881 ttgaggctga tgaagcggat attccggcgg ataaactgat ggcgctgccc tccagcgaaa
    23941 cctacggcga gattgacggc gtgctgggga acgacccggc gtacgggata ccggtcacct
    24001 ggatccagcc tgcgcagaaa gcgaaggctc tgaatatggg gtatcaggtg atcgacagcg
    24061 ccagtgtgat tgccaccatg tgaacaagat tgtgcgcagc tatattcctg atttgtttaa
    24121 ctatgatgac atcacgcagt tgcataaccg tttgtcgtcg atggcaccgc gcctggcgga
    24181 ggatttaagc gcggcgctca attacagcca attgctgaaa gtgtaccggg cgctgctgac
    24241 cgaaggcgtt tccctgcgcg atatcgtcac catcgccacc gtgctggtcg ccagtagcac
    24301 ggtgactaaa gatcatattc tgctggcggc cgatgtgcgc ctggcgctgc ggcgcagcat
    24361 tactcatccg ttcgttcgca agcaggagct gacggtgtat acgctgaata atgagctgg
//
