LOCUS       NZ_CP011653            16257 bp    DNA     circular CON 31-MAR-2024
DEFINITION  Citrobacter freundii strain CAV1741 plasmid pCAV1741-16, complete
            sequence.
ACCESSION   NZ_CP011653
VERSION     NZ_CP011653.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN03733754
            Assembly: GCF_001022275.1
KEYWORDS    RefSeq.
SOURCE      Citrobacter freundii
  ORGANISM  Citrobacter freundii
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Citrobacter; Citrobacter freundii complex.
REFERENCE   1  (bases 1 to 16257)
  AUTHORS   Sheppard,A.E., Stoesser,N., Wilson,D., Sebra,R., Kasarskis,A.,
            Anson,L., Giess,A., Pankhurst,L., Vaughan,A., Grim,C.J., Cox,H.,
            Yeh,A., Sifri,C.D., Walker,S., Peto,T.E., Crook,D.W. and
            Mathers,A.J.
  TITLE     Rapid spread of a carbapenem resistance gene driven by multiple
            levels of genetic mobility
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 16257)
  AUTHORS   Sheppard,A.E., Stoesser,N., Wilson,D., Sebra,R., Kasarskis,A.,
            Anson,L., Giess,A., Pankhurst,L., Vaughan,A., Grim,C.J., Cox,H.,
            Yeh,A., Sifri,C.D., Walker,S., Peto,T.E., Crook,D.W. and
            Mathers,A.J.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-JUN-2015) University of Oxford, John Radcliffe
            Hospital, Oxford OX39DU, United Kingdom
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP3 v. 2.2.0
            Genome Coverage                   :: 47X
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001022275.1-RS_2024_03_31
            Annotation Date                   :: 03/31/2024 01:56:02
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,287
            CDSs (total)                      :: 5,166
            Genes (coding)                    :: 5,044
            CDSs (with protein)               :: 5,044
            Genes (RNA)                       :: 121
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 84
            ncRNAs                            :: 12
            Pseudo Genes (total)              :: 122
            CDSs (without protein)            :: 122
            Pseudo Genes (ambiguous residues) :: 0 of 122
            Pseudo Genes (frameshifted)       :: 33 of 122
            Pseudo Genes (incomplete)         :: 81 of 122
            Pseudo Genes (internal stop)      :: 22 of 122
            Pseudo Genes (multiple problems)  :: 14 of 122
            Pseudo Genes (short protein)      :: 1 of 122
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP011653.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..16257
                     /organism="Citrobacter freundii"
                     /mol_type="genomic DNA"
                     /strain="CAV1741"
                     /isolation_source="Respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:546"
                     /plasmid="pCAV1741-16"
                     /geo_loc_name="USA:Virginia"
                     /lat_lon="38.14 N 78.45 W"
                     /collection_date="2012-10"
                     /collected_by="Clinical Microbiology University of Virginia
                     Health System"
     gene            join(15295..16257,1..15)
                     /locus_tag="AB183_RS00035"
                     /old_locus_tag="AB183_00035"
     CDS             join(15295..16257,1..15)
                     /locus_tag="AB183_RS00035"
                     /old_locus_tag="AB183_00035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006122493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6685 family protein"
                     /protein_id="WP_047722177.1"
                     /translation="MRYLTELICQLYRLTDHHKLTAATFKNLADIKLVEPTADADTILQ
                     LENIFSEYSLRYIDRDLAEILSNIITTDKKHSLDFDFNKLQSLTASKSFGCGWNKVING
                     SWFKNLYSWGEGMYPAKNLKAENISDWEDNIWHIEHEGFNPRDSINVTYYSWLDRYVAS
                     NSGGSHHAAMVVYQSVRDKLEYKREAVIEQLSINSNTVEILDQNYYSFIFQIKRPSNKT
                     EIYTSEYEFIDALKEFVENRYTILNPVNYVSSIKLVFIPKHALKTNDKTFRNWFYSAIS
                     CGKIISFPDYLKNPAHYHTHHYSHELNSITLGDPSRKYKLREDF"
                     /name="DUF6685 family protein"
     gene            complement(12..368)
                     /gene="ddp1"
                     /locus_tag="AB183_RS00040"
                     /old_locus_tag="AB183_00040"
     CDS             complement(12..368)
                     /gene="ddp1"
                     /locus_tag="AB183_RS00040"
                     /old_locus_tag="AB183_00040"
                     /inference="COORDINATES: protein motif:HMM:NF041452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA distortion polypeptide 3"
                     /protein_id="WP_044715127.1"
                     /translation="MKFDVKEFIDDKYAKAINILKENLKENYHVFYGIRLSEILFPASE
                     YGSDAFFKEFESINSVILPLVIFDLTQRKPMMIISFDKISDASLLAGTGIVVLECMALS
                     DLLTNDNIAILYKI"
                     /name="ddp1"
     gene            complement(542..985)
                     /locus_tag="AB183_RS00045"
                     /old_locus_tag="AB183_00045"
     CDS             complement(542..985)
                     /locus_tag="AB183_RS00045"
                     /old_locus_tag="AB183_00045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001074369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_044715130.1"
                     /translation="MAKIYDFPLGAERDKLRHEIDRERKKQRRVKTGNPFIRHVKWFCF
                     YLRLVTAGALHVVSVITLAVLGAFSKAIFWIGGMVCVVTWFHLERQFWTPHNFTIPVIV
                     SLWGLSLFATPLMEMINKKMPWYRLLVPDAKEASTETPDDESR"
                     /name="hypothetical protein"
     gene            complement(994..1881)
                     /locus_tag="AB183_RS00050"
                     /old_locus_tag="AB183_00050"
     CDS             complement(994..1881)
                     /locus_tag="AB183_RS00050"
                     /old_locus_tag="AB183_00050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122745.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_225622177.1"
                     /translation="MKNVTEKTKIRHRNEINKTLAQLPLAAKRVLCLALVYVDPKKEMR
                     MGQTFKIRADMYAKIAGIHPSVAYKQVKEGAELLNVSKLSLTGNDMKELAKELGLPNSK
                     NIDRLDLSITDYCAYNQNEGFVILRFGYTITPYISRLIGAENKFTTQLIASSLKLRGEY
                     SWSLYQLIRKNYSTFKGKNSFSLSLEELKDELIAYNIDDNGDIIYKYPEYPIFKREVIN
                     KAIKEIKEKTEVTFLSCVVDEKEGRKVSKLRFEYAIDEDKFAESGSDFPIELFDDDDSA
                     FLEEFDRKVPPKKK"
                     /name="replication initiation protein"
     gene            complement(3020..3238)
                     /locus_tag="AB183_RS00055"
                     /old_locus_tag="AB183_00055"
     CDS             complement(3020..3238)
                     /locus_tag="AB183_RS00055"
                     /old_locus_tag="AB183_00055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006122487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_044715134.1"
                     /translation="MHTRYIAPGTFASIGEPTSLDMSNNLLSPAKPISDYQTAFSLSQL
                     ARELANGTPGQCEALARGAVSARYEVR"
                     /name="hypothetical protein"
     gene            3497..3808
                     /locus_tag="AB183_RS28360"
                     /old_locus_tag="AB183_00060"
     CDS             3497..3808
                     /locus_tag="AB183_RS28360"
                     /old_locus_tag="AB183_00060"
                     /inference="COORDINATES: protein motif:HMM:NF013677.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="WP_047722173.1"
                     /translation="MTEKHRPSFSPEFKLEAAQLVTEKGYSTREAAEVMGVSHSAMRTW
                     VKQLRSERQGISPKASPLTPEQQKIRELERKIKRIEEEKEILKKATALLMSDSLNNSR"
                     /name="IS3 family transposase"
     gene            3712..4674
                     /locus_tag="AB183_RS00065"
                     /old_locus_tag="AB183_00065"
     CDS             3712..4674
                     /locus_tag="AB183_RS00065"
                     /old_locus_tag="AB183_00065"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="WP_224217850.1"
                     /translation="MREKNQTDRRGKRNFKKGYRSLDVGLPEQFSLVERLKKSFSVKRI
                     CDVFGIHRSSYKYWAARPQAISSEKVKLQAEVRKAHNDSKGSAGARTIADIVTSRGQSL
                     SRYRASKLMKELGLVSCQPPKHAYKKAHQEHVAIPNLLDRQFAVTAPNQVWCGDVTYIW
                     TGTQWAYLAVVLDLFARKPVGWAMSLSPDSELTSKALMVAFEARGRPKGLLFHSDQGSH
                     YTSRRFRQQLWRYQIRQSMSRRGNCWDNAPMERLFRSLKTEWMPTTGYRSVNEAKQAIT
                     DYLVGYYSQVRPHSYNGGLTPNESERLFWLEHKTVANFS"
                     /name="IS3 family transposase"
     gene            <4679..4885
                     /locus_tag="AB183_RS00070"
                     /old_locus_tag="AB183_00070"
                     /pseudo=""
     CDS             <4679..4885
                     /locus_tag="AB183_RS00070"
                     /old_locus_tag="AB183_00070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /name="DDE-type integrase/transposase/recombinase"
     gene            5335..6810
                     /gene="msr(E)"
                     /locus_tag="AB183_RS00075"
                     /old_locus_tag="AB183_00075"
     ARG             5336..6807
                     /name="msr(E)"
                     /gene="msr(E)"
                     /gene_name="ABC-F type ribosomal protection protein Msr(E)"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE/STREPTOGRAMIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            6866..7750
                     /locus_tag="AB183_RS00080"
                     /old_locus_tag="AB183_00080"
     CDS             6866..7750
                     /locus_tag="AB183_RS00080"
                     /old_locus_tag="AB183_00080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014325835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mph(E) family macrolide 2'-phosphotransferase"
                     /protein_id="WP_000155092.1"
                     /translation="MTIQDIQSLAEAHGLLLTDKMNFNEMGIDFKVVFALDTKGQQWLL
                     RIPRRDGMREQIKKEKRILELVKKHLSVEVPDWRISSTELVAYPILKDNPVLNLDAETY
                     EIIWNMDKDSPKYITSLAKTLFEIHSIPEKEVRENDLKIMKPSDLRPEIANNLQLVKSE
                     IGISEQLETRYRKWLDNDVLWADFTQFIHGDLYAGHVLASKDGAVSGVIDWSTAHIDDP
                     AIDFAGHVTLFGEESLKTLIIEYEKLGGKVWNKLYEQTLERAAASPLMYGLFALETQNE
                     SLIVGAKAQLGVI"
                     /name="Mph(E) family macrolide 2'-phosphotransferase"
     gene            7834..8538
                     /locus_tag="AB183_RS00085"
                     /old_locus_tag="AB183_00085"
     CDS             7834..8538
                     /locus_tag="AB183_RS00085"
                     /old_locus_tag="AB183_00085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_001067855.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            complement(<8905..9174)
                     /locus_tag="AB183_RS27570"
                     /old_locus_tag="AB183_00095"
                     /pseudo=""
     CDS             complement(<8905..9174)
                     /locus_tag="AB183_RS27570"
                     /old_locus_tag="AB183_00095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000015958.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            complement(9186..9377)
                     /locus_tag="AB183_RS28365"
     CDS             complement(9186..9377)
                     /locus_tag="AB183_RS28365"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_009873362.1"
                     /translation="MNHRYASEREATAAAKRLRPEQQHEWSSVSVFRKVWKRGSPLRAA
                     EVARNREWNQPVIPRYYD"
                     /name="hypothetical protein"
     gene            complement(9382..9720)
                     /locus_tag="AB183_RS26070"
     CDS             complement(9382..9720)
                     /locus_tag="AB183_RS26070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005291943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_071845138.1"
                     /translation="MERVGMDCRRCPLLALPAGAASRCMEPGHLDLNGSRRHLANGFTT
                     PRIGANQFLRRTVNAQTNPWQNISIASAISSSRTRRISGSVGSWPRVRMIVLLSLRTRL
                     GWRGCLTG"
                     /name="hypothetical protein"
     ARG             complement(9625..10814)
                     /name="tet(A)"
                     /gene="tet(A)"
                     /gene_name="major facilitator superfamily (MFS) antibiotic
                     efflux pump"
                     /tool="rgi"
                     /drug_class="tetracycline antibiotic"
                     /identity="96.72"
                     /coverage="93.4"
     ARG             complement(9637..10814)
                     /name="tet(A)"
                     /gene="tet(A)"
                     /gene_name="tetracycline efflux MFS transporter Tet(A)"
                     /tool="amrfinderplus"
                     /drug_class="TETRACYCLINE"
                     /identity="98.22"
                     /coverage="98.5"
     gene            10907..11566
                     /gene="tetR(C)"
                     /locus_tag="AB183_RS00110"
                     /old_locus_tag="AB183_00110"
     CDS             10907..11566
                     /gene="tetR(C)"
                     /locus_tag="AB183_RS00110"
                     /old_locus_tag="AB183_00110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance transcriptional repressor
                     TetR(C)"
                     /protein_id="WP_001038045.1"
                     /translation="MNKLQREAVIRTALELLNDVGMEGLTTRRLAERLGVQQPALYWHF
                     KNKRALLDALAEAMLTINHTHSTPRDDDDWRSFLKGNACSFRRALLAYRDGARIHAGTR
                     PAAPQMEKADAQLRFLCDAGFSAGDATYALMAISYFTVGAVLEQQASEADAEERGEDQL
                     TTSASTMPARLQSAMKIVYEGGPDAAFERGLALIIGGLEKMRLTTNDIEVLKNVDE"
                     /name="tetR(C)"
     gene            11553..12092
                     /locus_tag="AB183_RS26075"
                     /old_locus_tag="AB183_00115"
                     /pseudo=""
     CDS             11553..12092
                     /locus_tag="AB183_RS26075"
                     /old_locus_tag="AB183_00115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012710160.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /name="helix-turn-helix transcriptional regulator"
     gene            12399..13103
                     /locus_tag="AB183_RS00120"
                     /old_locus_tag="AB183_00120"
     CDS             12399..13103
                     /locus_tag="AB183_RS00120"
                     /old_locus_tag="AB183_00120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_001067855.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            complement(13246..13893)
                     /locus_tag="AB183_RS00125"
                     /old_locus_tag="AB183_00125"
     CDS             complement(13246..13893)
                     /locus_tag="AB183_RS00125"
                     /old_locus_tag="AB183_00125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016241263.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_024262784.1"
                     /translation="MTHTVPQSFVRAYLRASTSEQDASRALAAIDSFADERGLNICNYY
                     IENESGSRLDRPELFRLLNDCRQNDILLIEDVDRLSRLTGEDWNSLKKLIRQKDIRVMA
                     INVPTTWIASASHDFDSRMFAAINDMLLDMLAAVARRDYEQRRERQRQGINKAQKEGKY
                     KGRQVNQARYDAINRLLDSGSSWSQVQKIMACSRGTISSAVKSREDKRALSK"
                     /name="recombinase family protein"
     gene            14230..14892
                     /locus_tag="AB183_RS00130"
                     /old_locus_tag="AB183_00130"
     CDS             14230..14892
                     /locus_tag="AB183_RS00130"
                     /old_locus_tag="AB183_00130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_044715119.1"
                     /translation="MGKILLVVSDKGGVGKSTYSANTASMLANREKSVIILKTDKNNDL
                     ISWNEKRRENSLPTVPVYEAYGNVSKEINRLSKLCDVLIVDCPGHDSLEFRSALTVSDI
                     MITLVKASSDFESETLTSVTEKVRMAQKSNAALQPWVLLTRINPSKPRHRKAAIELDKL
                     LRSDDVWIQPLKNRMSELDVFESACNEGAGVHDVSRASSLTTAKAQIELVAQEIGII"
                     /name="AAA family ATPase"
     gene            14989..15270
                     /locus_tag="AB183_RS00135"
                     /old_locus_tag="AB183_00135"
     CDS             14989..15270
                     /locus_tag="AB183_RS00135"
                     /old_locus_tag="AB183_00135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001185482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_044715122.1"
                     /translation="MVLKLKTPTVPATEEQATNAETARFISGATRKPTPGKAKLVNFRL
                     SEAFDDILEAEAIRTGQSRTTVLKAALAAFDNLDENQKNHWLLESAKF"
                     /name="hypothetical protein"
     ARG             6867..7747
                     /name="mph(E)"
                     /gene="mph(E)"
                     /gene_name="Mph(E) family macrolide 2'-phosphotransferase"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             5336..6810
                     /name="msrE"
                     /gene="msrE"
                     /gene_name="msr-type ABC-F protein"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; streptogramin
                     antibiotic"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             6867..7750
                     /name="mphE"
                     /gene="mphE"
                     /gene_name="macrolide phosphotransferase (MPH)"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="100.0"
                     /coverage="100.0"
     Typing          complement(1194..1768)
                     /name="IncX5"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 agagaagatt tttagatttt atataaaata gcaatattat catttgtcag aagatcggac
       61 agagccatac attcaagaac cacaataccc gtccctgcca acaaactggc atcagatatc
      121 ttatcgaagc tgataatcat cattggcttg cgttgtgtta aatcaaagat tactaatggt
      181 agtattacac tgttaattga ttcaaattct ttaaagaaag catcagagcc atactcactg
      241 gcaggaaaaa gaatttcact caatctgatc ccataaaaaa catgatagtt ttctttgagg
      301 ttttccttta aaatattaat agcttttgcg tatttatcat caataaactc ttttacatca
      361 aacttcataa atcctccaac aagaaccgac tgtaggtcac cgggcaaacg agtaaaatgc
      421 tagcattttg cggcgtttgc cctatcctgc atcgcattga aaagaactca catcgcgcac
      481 tatgctaaac cgatggtata aggcaaacat gcacagtgca agcaggcagc ttgcgactgg
      541 ttcaccgcga ctcatcatca ggtgtctccg tgcttgcttc tttcgcatca ggaaccagga
      601 gacgatacca cggcattttt ttgtttatca tctccattag gggagtggca aacaaactca
      661 atccccacag gcttacgata acagggatcg tgaaattatg tggcgtccag aactggcgct
      721 caaggtgaaa ccatgtgacg acacaaacca tcccgccaat ccagaaaata gccttactga
      781 aagcccccaa tacagccagg gtaataacag aaactacatg cagtgcgcca gctgtgacaa
      841 ggcgaagata aaaacagaac catttaacgt gtcggataaa cggattgccc gtttttactc
      901 tacgttgctt tttacgttcc ctgtcaattt catgccttag tttgtctcgc tctgcgccca
      961 gcgggaaatc atagatttta gccataactc acctcatttc tttttgggtg gtacttttct
     1021 atcaaactcc tcaagaaaag cagaatcatc atcgtcaaat aactctatag gaaaatcaga
     1081 gcctgattcg gcaaatttat cttcatctat agcgtattca aatcgtaact tactaacttt
     1141 ccttccttct ttttcatcga caacgcaaga caggaaagtc acctcagttt tttcttttat
     1201 ttctttgatg gccttattta ttacctctcg cttgaatata gggtactctg gatacttata
     1261 tataatatct ccattatcat caatattgta agcaataagt tcatccttca actcttccag
     1321 agataggcta aatgaatttt tccctttaaa cgttgagtaa ttcttcctaa ttaactgata
     1381 caatgaccac gaatactccc ctctcaattt taatgaggac gcaattagtt gtgttgtgaa
     1441 tttattttcc gccccaatta atcttgatat ataaggcgtg atagtgtatc caaatcttag
     1501 aattacaaat ccctcatttt ggttatatgc acaataatca gtaatcgata agtcaaggcg
     1561 gtcgatgttt tttgaatttg gaagaccaag ttcctttgct aattccttca tatcattccc
     1621 cgtaagggaa agtttactga catttaacaa ttcagcacct tccttgactt gcttataagc
     1681 aacagaagga tgtattccgg ctatctttgc gtacatatca gcccgaattt taaaggtctg
     1741 ccccattctc atttcttttt ttggatcaac ataaaccaag gccagacaca gaaccctttt
     1801 ggctgccaat ggaagttgag ccagagtttt atttatttcg ttcctgtgac gaatcttcgt
     1861 tttttcagtt acatttttca taacttttat tctcataaaa cctctcacta aagagtagcc
     1921 acattaacat gatgaagtta ttttttccat catgtttatt cgcatttatc atcatgtttg
     1981 tccgcttagc gactcagcta aaccagacag gctccagcca atgtgctcat aaaacgcacg
     2041 ccttgatgac ttcacataca aagatcttca gatatgaagc ttttaaatca agctgttaat
     2101 agcgtcgcat tttccatcat gtttcgtcgc attttccatc atggtaaaac gcatttttca
     2161 tcatgcctcg tcgcatttcc catcatgttt aatcgcattt atcatcatgt ttcgtcgcat
     2221 ccaccatcat gtttagctta tttttcctat atatatcaga taattaaaaa cctctaattc
     2281 tttaagatct ttaagaaaag aaaatatata taaggctttt aatgcacagt acctgtggat
     2341 aactcagcat aaacccagag gatagatcct tctaaccttc ggaagttgga gcaaaacata
     2401 aggtgttcat attttagcca ttgagtgtac gtgctctctg tcagagcagc agatattccg
     2461 cttcctcgct ttggctgttc gttcctcgtc gctatgctcc tgcggtacgc ctcagccaaa
     2521 gactgcggcg agcggtgccg tctctcgatc acctaggtct gagaaaaggt gagaagaatt
     2581 ttaactcaaa aaaaagagat gttttaaact gttaaatcaa agagatacat tgagcaaaga
     2641 taacttaaaa gtaagatgat ttttaagtta tgcgtaaaaa acgggaaagg atcgtggagt
     2701 gatccttttt agatccagca ctaaaacgca ctcagaagcc ctcagaggcg ttttaagtga
     2761 gtttaccccg acgagggttc agcagaacgg ggtaaacccg cttagaacag catacagctc
     2821 gtttaacgta acaagctgga aattgaccag gagtgaactc cgcttacatg ggatgccagc
     2881 aaaattttac gaccggcaat gatggccagt tactttttgc tggctattgt cgcccagcag
     2941 ctggcggcct gattgttttt ttgctgtcag agttcgtcag gcatcaattg gtttcagcta
     3001 ctcgccacgt aatgcgctgc taacgcacct cataacgcgc agatacagcg ccccgcgcca
     3061 gtgcttcaca ctgccccggc gtaccgttcg ccagctcacg cgctaactgc gacaggctaa
     3121 acgccgtctg atagtcagaa attggcttag caggggagag gaggttattg ctcatatcca
     3181 ggcttgttgg ttcgccaata ctggcgaacg tccccggcgc gatgtaacga gtatgcaaaa
     3241 tgtgacacag ttcgcgcctc tttgaaacac ggttcaacag cgtaaagcat tcgctgtctt
     3301 tatagtgtct ttacactaca aagcaatcaa aaacaattgc attaccatca tatgatggta
     3361 tactgaattt gttggttggg aatggctccc tgccttaatc cagcagccca aacgggcggg
     3421 agtgtagtgg catagtgaat ttggccacct gattaaatcg cgtgatagga tcacgccctc
     3481 atagacaggt ggaaaaatga ccgaaaaaca cagaccctct tttagccccg aattcaaact
     3541 tgaagcggcc caactggtca ccgaaaaggg atacagcacc cgagaggctg cggaggtcat
     3601 gggcgtcagc catagcgcca tgcggacctg ggtgaaacag cttaggagtg agcgccaagg
     3661 catcagtccc aaggcctcgc cgctgacgcc agaacaacaa aaaatccgag aattagagag
     3721 aaaaatcaaa cggatagaag aggaaaaaga aattttaaaa aaggctaccg ctctcttgat
     3781 gtcggactcc ctgaacaatt ctcgctagtc gagcgactca agaagagctt tagcgtcaaa
     3841 cgcatctgcg atgtattcgg gatccatcgc agcagttata agtactgggc ggcgcgtcct
     3901 caagccatct cttcggagaa ggtaaagctg caagccgaag tccgtaaggc ccacaacgac
     3961 agcaagggct cagcgggtgc caggacgatt gcagacattg tcacgtcccg cggccagtct
     4021 ttaagccgct atcgggcaag caaactgatg aaggagctgg ggttggtcag ttgccagcca
     4081 cccaagcatg cttacaaaaa ggcgcatcaa gagcatgttg ccatccctaa cctattggat
     4141 aggcagttcg cggtgacggc gccgaatcaa gtctggtgtg gtgatgtgac ctacatctgg
     4201 accggaacgc aatgggccta tctggcggtg gtgctggacc tgtttgcccg caagccagtg
     4261 gggtgggcga tgtcgttgtc cccggatagc gagttgacca gcaaggcatt gatggtggct
     4321 tttgaggccc gaggccgacc caaggggcta ctgtttcatt ctgaccaggg aagccattac
     4381 accagccgtc gattccggca gcagctttgg cgctaccaga tcagacagag catgagccga
     4441 cgcggtaact gctgggacaa tgctccgatg gagcgattgt ttagaagctt aaagaccgag
     4501 tggatgccca cgaccggtta ccgcagtgtt aacgaagcca aacaggcaat cacggattat
     4561 ctggtgggct actacagcca ggttagaccg cactcctaca atggtggtct gacaccgaat
     4621 gaatccgaac gattgttctg gttagagcat aagaccgtgg ccaatttttc ttgaccacta
     4681 caggaacaac gtgattgaat gcgatcatgg caaactgaaa cggataatcg gcgccacgct
     4741 gggatttaaa tccatgaaga cggcttacgc caccatcaaa ggtattgagg tgatgcgtgc
     4801 actacgcaaa ggccaggcct cagcatttta ttatggtgat cccctgggcg aaatgcgcct
     4861 ggtaagcaga gtttttgaaa tgtaaggcct ttgaataaga caaaaggctg cctcatcgct
     4921 aactttgcaa cagtgcctaa aataagcctt atatccaagc ataaaacaag gttgtctaga
     4981 cttcttttaa cagtaaagtt atcataaaac tgaattttat tttttaggta agtttatgca
     5041 ttctatccgc attcgttaag acacaactat ttgcatagtg acactatttt ataatggtgg
     5101 gcttttgttg tgtctttaag aatatatgcg gatatataaa gtaaaagtat gcttaattta
     5161 taagtatgct tttagtgcat agtttccagt tataacttaa ttgactagct atttgtccac
     5221 cctgtggatg aatagctttt tttttgggag gacactgtga tgctagcttt tgttttcacc
     5281 taaatcctgt ttgctgcata aaaaatttca agagctaaac aggagtaaat aaaaatgagt
     5341 ttaattatta aagcgagaaa catacgcttg gattatgctg ggcgtgatgt tttggatatt
     5401 gatgaattgg aaattcactc ttatgaccgt attggtcttg tgggtgataa cggagcagga
     5461 aagagtagtt tactcaaagt acttaatggc gaaattgttt tagccgaagc gacattacag
     5521 cgttttggtg attttgcaca tatcagccaa ctgggcggaa tcgaaataga aacggtcgaa
     5581 gaccgggcaa tgttatctcg ccttggtgtt tccaatgtac aaaacgacac aatgagtggc
     5641 ggagaggaaa ctcgtgcaaa aattgctgcc gcattttccc aacaagtaca tggcattcta
     5701 gcggatgaac caaccagcca ccttgatctc aatggaatag atctacttat tggtcaactt
     5761 aaagcatttg atggagcatt acttgttatc agtcatgacc gatattttct tgatatggtt
     5821 gtagacaaga tatgggagtt aaaagacggt aaaattacgg aatattgggg tggttactcg
     5881 gattacttgc gtcaaaaaga agaagagcga caacaccaag ccgtagaata tgagctgatg
     5941 atgaaggaac gggagcgatt agaatctgct gtgcaagaaa aacgccagca agctaatcga
     6001 ttagacaata agaaaaaagg agaaaaatcc aaaaactcta ccgaaagtgc tggacgactt
     6061 gggcatgcaa aaatgactgg caccaagcaa agaaaactgt atcaggcagc taagagtatg
     6121 gaaaagcgtt tggctgcatt agaagatatt caagcaccag agcatttgcg ttctattcgt
     6181 tttcgtcaaa gttcagccct agaactgcac aataagttcc cgattacggc agatggtctg
     6241 agcttaaaat ttggtagccg tactatcttt gatgacgcta actttataat accgcttggc
     6301 gctaaagtcg ctataactgg atcgaatgga acagggaaaa cgtccttgtt aaaaatgata
     6361 tcagaacgtg ctgatggatt aaccatatct ccaaaagctg aaattggcta ctttacacaa
     6421 acaggatata aatttaacac gcataaatct gtgctctcct ttatgcagga agagtgcgag
     6481 tacacagttg cggaaattcg tgcagtattg gcttcaatgg ggatcggagc gaatgatatt
     6541 caaaaaaact tatccgactt atcgggaggt gaaatcatca aactgctttt atccaaaatg
     6601 cttttaggaa aatataatat tttgcttatg gatgaaccag gaaactatct tgacctaaaa
     6661 agtattgccg cattagaaac aatgatgaag tcctatgcag gaactattat cttcgtatct
     6721 catgacaagc aattggtcga taatattgct gacattatct acgagatcaa agaccacaaa
     6781 atcatcaaga cttttgagag agattgttaa tgatagccaa tctaatccga acattaatta
     6841 ttgaactctt taaaggaaat taaaaatgac aattcaagat attcaatcac ttgctgaagc
     6901 acacggcttg ttgcttacgg acaaaatgaa tttcaatgaa atgggcattg attttaaggt
     6961 cgtttttgct cttgatacaa aggggcaaca atggttgctg cgtattcctc gtcgtgatgg
     7021 catgagggaa caaatcaaga aagaaaaacg cattttagaa ttggtaaaaa aacatctttc
     7081 tgtagaggtt cctgattgga gaatttcatc tacagaatta gtggcttatc ccatacttaa
     7141 agataatcct gttttaaatt tggatgctga aacctatgaa ataatttgga atatggacaa
     7201 agatagcccg aaatacataa catctttggc aaaaacctta tttgaaatcc atagtattcc
     7261 tgaaaaagaa gttcgggaaa atgatttgaa aattatgaaa ccttcagatt taagacctga
     7321 aatagcaaac aatttgcagt tagtaaaatc tgaaattggt ataagtgagc aattggaaac
     7381 ccgctacaga aaatggttgg ataatgatgt tctatgggca gatttcaccc aatttataca
     7441 tggcgattta tatgctgggc atgtactagc ttcaaaggat ggagctgttt caggcgttat
     7501 tgattggtca acagcccata tagatgaccc agcgattgat tttgctgggc atgtaacttt
     7561 gtttggagaa gaaagcctca aaactctaat catcgagtat gaaaaactag ggggtaaagt
     7621 ttggaataaa ctatatgaac agactttaga aagagcagcg gcctctcctt tgatgtatgg
     7681 tttatttgcc ttagaaactc aaaatgaaag ccttatcgtt ggagcaaaag ctcagttggg
     7741 agttatataa tttaaaaata tgattgctga ggcactgttg caaatagtcg gtggtgataa
     7801 acttatcatc cccttttgct aatggagctg cacatgaacc cattcaaagg ccggcatttt
     7861 cagcgtgaca tcattctgtg ggccgtacgc tggtactgca aatacggcat cagttaccgt
     7921 gagctgcagg agatgctggc tgaacgcgga gtgaatgtcg atcactccac gatttaccgc
     7981 tgggttcagc gttatgcgcc tgaaatggaa aaacggctgc gctggtactg gcgtaaccct
     8041 tccgatcttt gcccgtggca catggatgaa acctacgtga aggtcaatgg ccgctgggcg
     8101 tatctgtacc gggccgtcga cagccggggc cgcactgtcg atttttatct ctcctcccgt
     8161 cgtaacagca aagctgcata ccggtttctg ggtaaaatcc tcaacaacgt gaagaagtgg
     8221 cagatcccgc gattcatcaa cacggataaa gcgcccgcct atggtcgcgc gcttgctctg
     8281 ctcaaacgcg aaggccggtg cccgtctgac gttgaacacc gacagattaa gtaccggaac
     8341 aacgtgattg aatgcgatca tggcaaactg aaacggataa tcggcgccac gctgggattt
     8401 aaatccatga agacggctta cgccaccatc aaaggtattg aggtgatgcg tgcactacgc
     8461 aaaggccagg cctcagcatt ttattatggt gatcccctgg gcgaaatgcg cctggtaagc
     8521 agagtttttg aaatgtaagg cctttgaata agacaaaagg ctgcctcatc gctaactttg
     8581 caacagtgcc cctgcgtgcg ctgctgccat gtccactacc tgacgccggt gatggtgatg
     8641 gcctcgccgg agcgggaatt tcttaacctc gacgaattta gacgatcggc gggcgagggg
     8701 atgtcgtggc aaggtccgcc ttgcgctgct ccgcaagggc gacaccagcg ggttcgtcgg
     8761 cggccacgcc tagcgcgacc gcaaccaagc gtcgaaaaag tatacgctcg tcacccgccg
     8821 tctcctgtgc tgagagtctc aggccgatcg gccggcaggg ctcaatgtca gcaaacgcgt
     8881 gatgagcggt ggccttcaac agtgataagg cggcaccaga gaaaaatcac tcagggtcaa
     8941 tgccagcgct tcgttaatac agatgtaggt gttccacagg gtagccagca gcatcctgcg
     9001 atgcagatcc ggaacataat ggtgcagggc gctgacttcc ggtgccagca gatattttgg
     9061 cagtttgcct tggatcagag ccatctgacg cagggctagt gcagccggat agtcaatagc
     9121 taccggcagc ggtgcggact gttgtaactc agaataagaa atgaggccgc tcatggcgtt
     9181 gactctcagt catagtatcg tggtatcacc ggttggttcc actctctgtt gcgggcaact
     9241 tcagcagcac gtaggggact tccgcgtttc cagactttac gaaacacgga aaccgaagac
     9301 cattcatgtt gttgctcagg tcgcagacgt tttgcagcag cagtcgcttc acgttcgctc
     9361 gcgtatcggt gattcattct gctaaccagt aaggcaaccc cgccagccta gccgggtcct
     9421 caacgacagg agcacgatca tgcgcacccg tggccaggac ccaacgctgc ccgagatgcg
     9481 ccgcgtgcgg ctgctggaga tggcggacgc gatggatatg ttctgccaag ggttggtttg
     9541 cgcattcaca gttctccgca agaattgatt ggctccaatt cttggagtgg tgaatccgtt
     9601 agcgaggtgc cgccggcttc cattcaggtc gaggtggccc ggctccatgc accgcgacgc
     9661 agcgccggca ggcagagcaa gtagagggca gcgcctgcaa tccatgccca cccgttccac
     9721 gttgttatag aagccgcata gatcgccgtg aagaggaggg gtccgacgat cgaggtcagg
     9781 ctggtgagcg ccgccagtga gccttgcagc tgcccctgac gttcctcatc cacctgcctg
     9841 gacaacattg cttgcagcgc cggcattccg atgccacccg aagcaagcag gaccatgatc
     9901 gggaacgcca tccatccccg tgtcgcgaag gcaagcagga tgtagcctgt gccgtcggca
     9961 atcattccga gcatgagtgc ccgcctttcg ccgagccggg cggctacagg gccggtgatc
    10021 attgcctggg cgagtgaatg cagaatgcca aatgcggcaa gcgaaatgcc gatcgtggtc
    10081 gcgtcccagt gaaagcgatc ctcgccgaaa atgacccaaa gcgcggccgg cacctgtccg
    10141 acaagttgca tgatgaagaa gaccgccatc agggcggcga cgacggtcat gccccgggcc
    10201 caccggaacg aagcgagcgg gttgagagcc tcccggcgta acggccggcg ttcgcctttg
    10261 tgcgactccg gcaaaaggaa acagcccgtc aggaaattga ggccgttcaa ggctgccgcg
    10321 gcgaagaacg gagcgtgggg ggagaaaccg cccatcagcc caccgagcac aggtcccgcg
    10381 accatcccga acccgaaaca ggcgctcatg aagccgaagt gccgcgcgcg ctcatcgcca
    10441 tcagtgatat cggcaatata agcgccggct accgccccag tcgccccggt gatgccggcc
    10501 acgatccgcc cgatatagag aacccaaagg aaaggcgccg tcgccatgat ggcgtagtcg
    10561 acagcagcgc cggccagcga gacgagcaag accggccgcc gcccgaaacg atccgacagc
    10621 gcgcccagca caggtgcgca ggcaaattgc atcaacgcat acagcgccag cagaatgcca
    10681 tagtgggcgg tgacgtcgtt cgagtgaacc agatcgcgca ggaggcccgg cagcaccggc
    10741 ataatcaggc cgatgccgac agcatccagg gtgacggtgc cgaggatgac gatgagcgca
    10801 ttgttagatt tcatacacgg tgcctgactg cgttagcaat ttaactgtga taaactaccg
    10861 cattaaagct tatcgatgat aagctgtcaa acatgagaat tcgcgaatga acaagctcca
    10921 acgcgaggcc gtgatccgaa ccgcgctcga actgcttaac gacgtgggca tggaaggtct
    10981 aacgacgcgc cgactggctg agcgcctcgg ggtgcaacag ccagcgctct actggcattt
    11041 caagaacaag cgtgcgttgc tcgacgcact tgccgaagcc atgctgacga taaatcacac
    11101 gcattcgacg ccaagggatg acgacgactg gcgttcgttc ctgaagggca atgcatgcag
    11161 ttttcgacgg gcgttgctcg cttatcgcga tggcgcgcgt attcatgccg ggacgcggcc
    11221 agccgcgccg cagatggaaa aagccgacgc gcagcttcgc ttcctttgcg atgctggctt
    11281 ttcggcaggt gacgcgacct atgcgttgat ggcaatcagc tacttcaccg tcggcgctgt
    11341 tcttgagcag caagctagcg aggcagacgc cgaggagcgg ggcgaagatc agttgaccac
    11401 ctcagcgtct acgatgccgg cgcgcctaca gagcgcgatg aaaatcgtct acgaaggcgg
    11461 tccggacgcg gcattcgagc gaggcctggc tctcatcatc ggcggtcttg aaaaaatgag
    11521 gctcactacg aacgacattg aggtgctgaa gaatgttgac gaatgacagg gggcggcagg
    11581 tgcggagggc gcggttgctt cgtcatatga agcaaagtca cctagctgaa ttaatgggtg
    11641 tggatcaggc aaccgtgtcg cgctgggagc ggggcaccct tgcattgtcg gatgggaggt
    11701 ggtcagcggt tcttcaattg cttaccgggc cttccgattc atcgtacgac gctgcgctga
    11761 agcgtctggt gcaatcctcc gcccacaaag tccatctggt agcgaccgga cacattgttt
    11821 gctcgcggca tctccggcca ggcaaaggga attgcggatt gacctagccg aactccttgg
    11881 taaatcgctg cgtgtttatg cgtccccgag atagttgcgg ccgactctgc gcttaatggg
    11941 ctcggttggc atgaggggcg gctggggtca ctcgaggtgg ataccggccc gaactggagc
    12001 gaggaacttc catactgcca aggcgaatgc tgtgggagcg catcatgctc gctgatggta
    12061 gcccggcact acttgttacc accacagctt aatgcgaagg gtgctcctgt tcttgtgcat
    12121 attttatgcg ctgctgattg tgcatcgaac tgataacctc aacgggtctg ctttgtagtt
    12181 caccacaccc ctgacgcgcg cgtgccggat aagcagaact atggtgccga tggatgtcag
    12241 gaacactcgg cctggttcgt aactaggtcg tcctgcgcga tcctgcggct agggccggaa
    12301 tcgtgctcgc cagtcaggcg ctgatgaagc ctatgggcac tgttgcaaat agtcggtggt
    12361 gataaactta tcatcccctt ttgctgatgg agctgcacat gaacccattc aaaggccggc
    12421 attttcagcg tgacatcatt ctgtgggccg tacgctggta ctgcaaatac ggcatcagtt
    12481 accgtgagct gcaggagatg ctggctgaac gcggagtgaa tgtcgatcac tccacgattt
    12541 accgctgggt tcagcgttat gcgcctgaaa tggaaaaacg gctgcgctgg tactggcgta
    12601 acccttccga tctttgcccg tggcacatgg atgaaaccta cgtgaaggtc aatggccgct
    12661 gggcgtatct gtaccgggcc gtcgacagcc ggggccgcac tgtcgatttt tatctctcct
    12721 cccgtcgtaa cagcaaagct gcataccggt ttctgggtaa aatcctcaac aacgtgaaga
    12781 agtggcagat cccgcgattc atcaacacgg ataaagcgcc cgcctatggt cgcgcgcttg
    12841 ctctgctcaa acgcgaaggc cggtgcccgt ctgacgttga acaccgacag attaagtacc
    12901 ggaacaacgt gattgaatgc gatcatggca aactgaaacg gataatcggc gccacgctgg
    12961 gatttaaatc catgaagacg gcttacgcca ccatcaaagg tattgaggtg atgcgtgcac
    13021 tacgcaaagg ccaggcctca gcattttatt atggtgatcc cctgggcgaa atgcgcctgg
    13081 taagcagagt ttttgaaatg taaggccttt gaataagaca aaaggctgcc tcatcgctaa
    13141 ctttgcaaca gtgcccaaaa attttcgata tccaaactga cccctattga acaatcacac
    13201 aagccaacca gctaggacgg gtagacattt tcttgtgtgt tgtaactact tactcaaagc
    13261 acgtttatct tccctcgatt ttacagcact actaattgtc cctcgactac aggccataat
    13321 tttctgaacc tggctccaag aactaccgct atcgagcaac cgattaattg catcgtatcg
    13381 agcctgattg acctgacgcc ccttatattt tccctccttt tgagctttat taatcccctg
    13441 cctttggcgt tcccggcgtt gttcataatc acgacgagcc acagcagcca gcatatcaag
    13501 caacatatcg ttgattgcag caaacatgcg actatcaaaa tcatggctcg ctgaagcaat
    13561 ccaggttgtc ggtacgttga tggccatcac tcgaatatcc ttctggcgaa tcaacttctt
    13621 caggctgttc cagtcttcac cagttaagcg tgaaagccga tcaacatctt caatgaggag
    13681 aatatcgttc tgtcggcagt cgttcagcag tctgaataat tccggtcggt cgagccgcga
    13741 accagattca ttctcgatgt agtaattgca gatgttaagg ccacgctcat cagcaaagct
    13801 atcgatcgca gcgagtgcgc gagaagcgtc ttgttcagat gttgaggcgc gtaaataagc
    13861 ccggacaaag ctttgcggta cggtatgagt cacaatgtcg aaccagttca atttaggtta
    13921 ttaaagcata accatatagt acctgtttcg catggtattt taaaggcata ctcaaaccga
    13981 accaaagaaa tgattcatta tgtgaccacg tcacctacag ttacatcaga aagacggtgt
    14041 aaatcaaacg taaagccata atgagcttta ccatgtaaag cacacataaa gacacactta
    14101 tctttatact ctatttacat cgtaaaacat aaagagtata aagacactat aaagacgcct
    14161 atatctttat aagttaaaga caccgtaaag acatgaaaag ctttacatcg taaatacgag
    14221 gatgcggaaa tgggaaaaat tttactggtg gtttcagata agggcggggt agggaaaagc
    14281 acctactcag ctaacacagc atctatgctg gcaaacagag aaaaatcggt aatcatcctt
    14341 aaaaccgata agaacaatga ccttatcagc tggaatgaaa aacgcaggga gaatagcctc
    14401 ccaacagtac cagtctacga ggcatacggt aatgtaagca aagagattaa ccgcctgagc
    14461 aagctgtgcg atgttctgat cgttgactgc cccggacatg acagccttga gttccgtagc
    14521 gcactgactg tgtcagatat catgataact ctggttaaag cgtcatctga ctttgaaagt
    14581 gaaacactga cgagcgtaac cgagaaagtc cgcatggctc agaaatcaaa cgcagccctg
    14641 caaccctggg tattacttac cagaataaac ccaagcaagc cacgccacag aaaagccgct
    14701 attgagctgg ataaattatt acgctcagac gacgtctgga tacagccact aaaaaaccgc
    14761 atgtcagaat tggatgtgtt tgaaagcgcc tgcaatgaag gggcaggggt acatgatgta
    14821 agccgcgcct ccagtctgac aacagcaaaa gcacagatag aattagtcgc ccaggaaata
    14881 gggataatct aaatatttca atcgaataca tagaaattta cattgtaaag acaacataaa
    14941 gacactatag tatttacact tagatagtgt ctttaatgag gattttgtat ggttttaaaa
    15001 ttgaaaacgc caaccgttcc ggcgacagaa gaacaggcaa caaacgcaga aacagcacgc
    15061 tttatctctg gagccacaag gaagccaaca ccaggtaaag cgaagctggt taatttccgg
    15121 ctttctgaag cctttgacga tatcctagag gctgaggcga tcagaacagg acagagcagg
    15181 acaaccgttc taaaggcagc gctggccgca tttgataatc tggacgaaaa ccagaaaaac
    15241 cactggttac tggaatcagc aaaattctaa ccatagaagc atggatgata atctatgaga
    15301 tatttaaccg aattaatctg tcaactctac aggttgacag atcaccataa gctgaccgct
    15361 gcaacgttta aaaatcttgc tgatattaag ttagttgaac ctacagcgga tgcagacacc
    15421 atattgcagc ttgaaaatat atttagcgaa tactcactga gatatattga cagggatctg
    15481 gctgagattc tgagtaacat aataactaca gataaaaaac actctctgga tttcgatttt
    15541 aacaaattac agtctctgac tgcctcgaaa agtttcggtt gtggatggaa caaggtaata
    15601 aatggtagtt ggttcaaaaa cctttactca tggggggagg ggatgtatcc cgccaaaaac
    15661 ctgaaagctg aaaacatttc agactgggag gataatatat ggcacattga gcatgaaggt
    15721 ttcaaccctc gcgattctat caatgttaca tattactcct ggcttgaccg ctatgtagct
    15781 tcaaacagtg gtggttcaca tcatgcagca atggttgtat atcaatctgt cagagacaaa
    15841 ttagagtata aacgagaagc ggttattgaa caactgagca taaattcaaa caccgttgaa
    15901 atacttgacc agaactacta ttcattcata ttccagataa aacgccctag taataagaca
    15961 gaaatttata catcagaata tgaatttata gatgctttaa aagagtttgt agaaaacaga
    16021 tatactatac ttaatcctgt caattacgtt tccagtatta aattagtttt tattccaaaa
    16081 catgcactaa aaacaaatga caaaactttc cgtaactggt tctattctgc aattagttgc
    16141 gggaaaataa tatcattccc cgattatctg aaaaatccag cgcattacca tacacaccat
    16201 tactcacatg aactaaactc gataacactt ggtgacccta gcagaaagta taaactg
//
