LOCUS       NZ_CP011284            37865 bp    DNA     circular CON 28-JAN-2024
DEFINITION  Enterococcus faecium strain E39 plasmid p4, complete sequence.
ACCESSION   NZ_CP011284
VERSION     NZ_CP011284.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN03486724
            Assembly: GCF_001635875.1
KEYWORDS    RefSeq.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 37865)
  AUTHORS   Huang,W., Wang,G., Zhuge,J., Ojaimi,C., Dimitrova,N. and Fallon,J.T.
  TITLE     Enterococcus faecium E39, a daptomycin-resistant strain
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 37865)
  AUTHORS   Huang,W., Wang,G., Zhuge,J., Ojaimi,C., Dimitrova,N. and Fallon,J.T.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-APR-2015) Pathology, New York Medical College, 15 Dana
            Road, Valhalla, NY 10595, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: SPAdes v. 3.5.0; HGAP Assembly v. 3
            Genome Coverage                   :: 460
            Sequencing Technology             :: Illumina; Pacific Biosciences
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/28/2024 08:32:41
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,068
            CDSs (total)                      :: 2,976
            Genes (coding)                    :: 2,858
            CDSs (with protein)               :: 2,858
            Genes (RNA)                       :: 92
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 43 of 118
            Pseudo Genes (incomplete)         :: 64 of 118
            Pseudo Genes (internal stop)      :: 32 of 118
            Pseudo Genes (multiple problems)  :: 17 of 118
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP011284.1.
            Bacteria available from Guiqing Wang (WangG@WCMC.com).
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..37865
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /strain="E39"
                     /isolation_source="blood of a hospitalized patient"
                     /db_xref="taxon:1352"
                     /plasmid="p4"
                     /geo_loc_name="USA: New York, NY"
                     /collection_date="2009-05-28"
     gene            1..1041
                     /locus_tag="XM37_RS14635"
                     /old_locus_tag="XM37_14945"
     CDS             1..1041
                     /locus_tag="XM37_RS14635"
                     /old_locus_tag="XM37_14945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_000997689.1"
                     /translation="MNDFNYYKSKEIYREKYYQMPKVFFTNEKYMDLSNDAKIAYMLLK
                     DRFDYSVKNNWVDSDDNIFFIFTVEELMKLLQCREGKVSKIKKELEKAGLLKQKRGRVN
                     KRDGKIESMPNLLYLGKPEVTNQDVFKIMEEEDNTDTTVIAKIANTAKPREINDTTVIA
                     KIANTAKSSHIKDSTVIAKIADNLFYSNSIDTNRHIIDTETDQLQNQVLLDNFVDIMKE
                     DSINTFVPENVLNLIKTFSSTYEDAQKTVQTIHNAKKKAEELEQTVVVYEELESYGIDA
                     DKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFVEKAIAAKLANEQRETFNELPTVS
                     TENWLE"
                     /name="replication initiator protein A"
     gene            complement(1657..2337)
                     /locus_tag="XM37_RS14640"
                     /old_locus_tag="XM37_14950"
     CDS             complement(1657..2337)
                     /locus_tag="XM37_RS14640"
                     /old_locus_tag="XM37_14950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_002343844.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIGADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKLYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            2483..2566
                     /locus_tag="XM37_RS14645"
                     /old_locus_tag="XM37_14955"
     CDS             2483..2566
                     /locus_tag="XM37_RS14645"
                     /old_locus_tag="XM37_14955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /GO_process="GO:0046677 - response to antibiotic [Evidence
                     IEA]; GO:0031556 - transcriptional attenuation by ribosome
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="WP_001814874.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
                     /name="23S rRNA methyltransferase attenuation leader
                     peptide"
     gene            2691..3428
                     /gene="erm(B)"
                     /locus_tag="XM37_RS14650"
                     /old_locus_tag="XM37_14960"
     ARG             2692..3425
                     /name="erm(B)"
                     /gene="erm(B)"
                     /gene_name="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /tool="amrfinderplus"
                     /drug_class="LINCOSAMIDE/MACROLIDE/STREPTOGRAMIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            <3598..3858
                     /locus_tag="XM37_RS16305"
                     /pseudo=""
     CDS             <3598..3858
                     /locus_tag="XM37_RS16305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /GO_component="GO:0005694 - chromosome [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003916 - DNA topoisomerase activity [Evidence IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
                     /name="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
     gene            4021..>4686
                     /locus_tag="XM37_RS14655"
                     /old_locus_tag="XM37_14965"
                     /pseudo=""
     CDS             4021..>4686
                     /locus_tag="XM37_RS14655"
                     /old_locus_tag="XM37_14965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558228.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element IS1182 family transposase"
                     /name="IS1182-like element IS1182 family transposase"
     gene            4722..4967
                     /locus_tag="XM37_RS14660"
                     /old_locus_tag="XM37_14970"
     CDS             4722..4967
                     /locus_tag="XM37_RS14660"
                     /old_locus_tag="XM37_14970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="WP_000567888.1"
                     /translation="MIDVNELLEEAIRETENLNDGEVFLVKDLFKGYVGNRIPRKDRLL
                     LGTLFLNHVSKMNGNLKAIEKTSSNQQRYKKTIDKF"
                     /name="single-stranded DNA-binding protein"
     gene            5070..5939
                     /locus_tag="XM37_RS14665"
                     /old_locus_tag="XM37_14975"
     CDS             5070..5939
                     /locus_tag="XM37_RS14665"
                     /old_locus_tag="XM37_14975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing protein"
                     /protein_id="WP_000228166.1"
                     /translation="MVDNIIKSVAEKLSSLSYIEGIVLGGSRARGTHTEDSDIDIGIYY
                     NSESFDINTINQFATKLDDEHRNNLVVPPGAWGDWINGGGWLVINGYHVDLILRDIKRV
                     EQIMKDTEHGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAETYPNA
                     LQKSLVNFFMFEAGFSLMFVKANSGTDDKYYIAGHVFRIVSCLNQVLFACNNAYCINEK
                     KAIKLLETFEHKPEKYTEKVNHIFEVLGISLFECYDMTEKLYNEVNEIVSEINNFLNEE
                     SSDERKQI"
                     /name="nucleotidyltransferase domain-containing protein"
     gene            5920..6654
                     /locus_tag="XM37_RS14670"
                     /old_locus_tag="XM37_14980"
     CDS             5920..6654
                     /locus_tag="XM37_RS14670"
                     /old_locus_tag="XM37_14980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]; GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_000662263.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGKR
                     VLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDFPE
                     ESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNEKGE
                     ILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPENMMD
                     IPGMADEMRRPMMLIVSAKKKM"
                     /name="class I SAM-dependent methyltransferase"
     gene            6687..7599
                     /gene="ant(6)"
                     /locus_tag="XM37_RS14675"
                     /old_locus_tag="XM37_14985"
                     /pseudo=""
     CDS             6687..7599
                     /gene="ant(6)"
                     /locus_tag="XM37_RS14675"
                     /old_locus_tag="XM37_14985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /name="ant(6)"
     gene            7596..8138
                     /gene="sat4"
                     /locus_tag="XM37_RS14680"
                     /old_locus_tag="XM37_14990"
     ARG             7597..8135
                     /name="sat4"
                     /gene="sat4"
                     /gene_name="streptothricin N-acetyltransferase Sat4"
                     /tool="amrfinderplus"
                     /drug_class="STREPTOTHRICIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            8231..9025
                     /gene="aph(3')-IIIa"
                     /locus_tag="XM37_RS14685"
                     /old_locus_tag="XM37_14995"
     ARG             8232..9022
                     /name="aph(3')-IIIa"
                     /gene="aph(3')-IIIa"
                     /gene_name="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            9301..9792
                     /locus_tag="XM37_RS14690"
                     /old_locus_tag="XM37_15000"
     CDS             9301..9792
                     /locus_tag="XM37_RS14690"
                     /old_locus_tag="XM37_15000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="WP_063526669.1"
                     /translation="MNRINRVTSILIQLQSKKIIPAKEIAQRFNISLRTVYRDIRTLEE
                     AGIPIGSEAGKGYFLVEGFLLPPVMFTAAEVGALITAGKFLNCHGDESFIKDFDSAMYK
                     IKSILKHGEKNYAQELENSINVYSTSGQKNTLADNVIAAIQTAICNKRVRFCCKVLNKE
                     "
                     /name="HTH domain-containing protein"
     gene            complement(9815..10495)
                     /locus_tag="XM37_RS14695"
                     /old_locus_tag="XM37_15005"
     CDS             complement(9815..10495)
                     /locus_tag="XM37_RS14695"
                     /old_locus_tag="XM37_15005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            complement(<10570..10764)
                     /locus_tag="XM37_RS14700"
                     /old_locus_tag="XM37_15010"
                     /pseudo=""
     CDS             complement(<10570..10764)
                     /locus_tag="XM37_RS14700"
                     /old_locus_tag="XM37_15010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342725.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            complement(<11307..13457)
                     /locus_tag="XM37_RS14705"
                     /old_locus_tag="XM37_15015"
                     /pseudo=""
     CDS             complement(<11307..13457)
                     /locus_tag="XM37_RS14705"
                     /old_locus_tag="XM37_15015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684984.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /name="Tn3 family transposase"
     gene            13603..14178
                     /locus_tag="XM37_RS14710"
                     /old_locus_tag="XM37_15020"
     CDS             13603..14178
                     /locus_tag="XM37_RS14710"
                     /old_locus_tag="XM37_15020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001226076.1"
                     /translation="MRKIGYIRVSSTNQNPSRQFQQLNEIGMDIIYEEKVSGATKDREQ
                     LQKVLDDLQEDDIIYVTDLTRITRSTQDLFELIDNIRDKKASLKSLKDTWLDLSEDNPY
                     SQFLITVMAGVNQLERDLIRMRQREGIELAKKEGKFKGRLKKYHKNHAGMNYAVKLYKE
                     GNMTVNQICEITNVSRASLYRKLSEVNN"
                     /name="recombinase family protein"
     gene            14392..15087
                     /gene="vanR-A"
                     /locus_tag="XM37_RS14715"
                     /old_locus_tag="XM37_15025"
     ARG             14393..15084
                     /name="vanR-A"
                     /gene="vanR-A"
                     /gene_name="vancomycin resistance response regulator
                     transcription factor VanR-A"
                     /tool="amrfinderplus"
                     /drug_class="GLYCOPEPTIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            15065..16219
                     /locus_tag="XM37_RS14720"
                     /old_locus_tag="XM37_15030"
     CDS             15065..16219
                     /locus_tag="XM37_RS14720"
                     /old_locus_tag="XM37_15030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance histidine kinase VanS-A"
                     /protein_id="WP_002305818.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGKL
                     GDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKYFD
                     EINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVMYLA
                     HDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRYNLQT
                     ITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFNNILKN
                     AAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSSDTGGAG
                     LGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
                     /name="vancomycin resistance histidine kinase VanS-A"
     gene            complement(16317..17609)
                     /locus_tag="XM37_RS14725"
                     /old_locus_tag="XM37_15035"
     CDS             complement(16317..17609)
                     /locus_tag="XM37_RS14725"
                     /old_locus_tag="XM37_15035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628567.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1251 family transposase"
                     /protein_id="WP_000122610.1"
                     /translation="MSYTHLIKETLDILDLSVTFNENCLTKEKYKGQICHIYRGNLIYT
                     AQECIHCKHQIASDIVRWGTTTVRLLMNDVSEYRTYLELKKQRFKCKACQRTFVADTSV
                     AKKHCFISEKVRWSVVTRLKKNTSMTEIAAQKNLSVSSVYRIMKRFYRPLNPFRTPLPK
                     VLCFDEFKSVRGVSGAMSFIMMDGQTQRLLDIVENRQLPFLKRYFSHFSREIREAVEWI
                     VIDMYAPYVSLVKKLFPKAQLIIDRFHIVQHIGRTFRNHRIKETNQLLKSKEQKHYQLG
                     KQLKRYWKLLQKDERKLDYTRRLWRPGFKAHLTETDIVDRLLKGSPALRVGYQLYQDFL
                     YAVKERDYVSFEELLTNNIMLPEGYQTTLRTFQKFLPQIKNALQQSYSNGPLECLNNHI
                     KVLKRNAYGFRSFYNFKLRIMIRHGNALIFN"
                     /name="ISL3-like element IS1251 family transposase"
     gene            17941..18909
                     /locus_tag="XM37_RS14730"
                     /old_locus_tag="XM37_15040"
     CDS             17941..18909
                     /locus_tag="XM37_RS14730"
                     /old_locus_tag="XM37_15040"
                     /EC_number="1.1.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="WP_001059542.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKSA
                     PFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAYSP
                     DSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKAVIE
                     RLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQRMKQ
                     GAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQFLLKL
                     QRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
                     /name="D-lactate dehydrogenase VanH-A"
     gene            18902..19933
                     /gene="vanA"
                     /locus_tag="XM37_RS14735"
                     /old_locus_tag="XM37_15045"
     ARG             18903..19930
                     /name="vanA"
                     /gene="vanA"
                     /gene_name="D-alanine--(R)-lactate ligase VanA"
                     /tool="amrfinderplus"
                     /drug_class="GLYCOPEPTIDE"
                     /identity="99.71"
                     /coverage="100.0"
     gene            19939..20547
                     /locus_tag="XM37_RS14740"
                     /old_locus_tag="XM37_15050"
     CDS             19939..20547
                     /locus_tag="XM37_RS14740"
                     /old_locus_tag="XM37_15050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="WP_000402348.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTYE
                     LAESLLKAKELAATQGYGLLLWDGYRPNRAVNCFMQWAAQPENNLTKESYYPNIDRTEM
                     ISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEAQNR
                     RRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
                     /name="D-Ala-D-Ala dipeptidase VanX-A"
     gene            complement(20711..21391)
                     /locus_tag="XM37_RS14745"
                     /old_locus_tag="XM37_15055"
     CDS             complement(20711..21391)
                     /locus_tag="XM37_RS14745"
                     /old_locus_tag="XM37_15055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            21765..22676
                     /locus_tag="XM37_RS14750"
                     /old_locus_tag="XM37_15060"
     CDS             21765..22676
                     /locus_tag="XM37_RS14750"
                     /old_locus_tag="XM37_15060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="WP_001812592.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHLE
                     NSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLLDS
                     NIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGYSEH
                     NSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIRYVGL
                     PHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNLRYEIS
                     GNNIDGVIVTVFPGSTHTNSRR"
                     /name="D-Ala-D-Ala carboxypeptidase VanY-A"
     gene            22829..23314
                     /gene="vanZ-A"
                     /locus_tag="XM37_RS14755"
                     /old_locus_tag="XM37_15065"
     ARG             22830..23311
                     /name="vanZ-A"
                     /gene="vanZ-A"
                     /gene_name="glycopeptide resistance protein VanZ-A"
                     /tool="amrfinderplus"
                     /drug_class="GLYCOPEPTIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(23601..23930)
                     /locus_tag="XM37_RS14760"
                     /old_locus_tag="XM37_15070"
     CDS             complement(23601..23930)
                     /locus_tag="XM37_RS14760"
                     /old_locus_tag="XM37_15070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754864.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000754864.1"
                     /translation="MKKVCQVTVVHKEKVNGIKNKLDQKDFSNLLVLGKCFSDFSRIKI
                     FYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDILS
                     AIRVF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            24235..24564
                     /locus_tag="XM37_RS14765"
                     /old_locus_tag="XM37_15075"
     CDS             24235..24564
                     /locus_tag="XM37_RS14765"
                     /old_locus_tag="XM37_15075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000629052.1"
                     /translation="MITKTRKQGNSIMLTVPKEFDVPNGVEVEAKLVENGILYEFVEPK
                     KEFFDFSEDILADILSEGYSKQEILKEFRNRKNALTSAFKSIAEDTVANSKPMTKEELA
                     AEIGL"
                     /name="hypothetical protein"
     gene            24554..24841
                     /locus_tag="XM37_RS14770"
                     /old_locus_tag="XM37_15080"
     CDS             24554..24841
                     /locus_tag="XM37_RS14770"
                     /old_locus_tag="XM37_15080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000312842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_000312841.1"
                     /translation="MAYEILPSKHVIKYLKKLKEKTLKEQFLTIIYDEIAVRPHSGEQK
                     TGDLSGIWAIGFKYAGTTYRVAYEIKDNAVIPILLCGTHENFYEQLKKIR"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(25120..25683)
                     /locus_tag="XM37_RS14775"
                     /old_locus_tag="XM37_15085"
     CDS             complement(25120..25683)
                     /locus_tag="XM37_RS14775"
                     /old_locus_tag="XM37_15085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000017403.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000017403.1"
                     /translation="MSGYIYGYARVSTRSQELNRQLDLLNEQNCNEILTEKMTGTKAVR
                     PQLNRLKDKIRPGDTVIVESFSRLGRSTKDLIDLVTYFEEHHVKLVSLKENFDTSTPHG
                     RLMMTVFQAFSQFERDLIVERTKEGLKSARARGRKGGRPRVNQKDVDRAVKLYKSQVYS
                     VKEITEMTGISKATLYRYLKDNRE"
                     /name="recombinase family protein"
     gene            26326..27279
                     /locus_tag="XM37_RS14780"
                     /old_locus_tag="XM37_15090"
     CDS             26326..27279
                     /locus_tag="XM37_RS14780"
                     /old_locus_tag="XM37_15090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="WP_000222571.1"
                     /translation="MTYTHLTPNELVMIEAYFHQETPVAIVAKQLKRGRQTIYNVYNFL
                     KCGGTALEYFEQYKENKRRCGRTEIIFPAEEKEYIEKRSTEGWTPDVIIGRAERTFSCS
                     ISTLYRRFKTGEFNVLHLPMQGKRKPNGYKEKRGKQAFKRNISERKKDYVVFEEEFGHL
                     EGDTIVGIHHKSAVITLVERLSKAIIVLKPEGRKAVDIENSINEWLQSVPKNLFKSITF
                     DCGKEFSNWKSISNTNDIDIYFADPGTPSQRGLNEHSNGLLRKDGLPKEMDFNQVNQGF
                     ISSVASKRNHIPRKSLNYQTPLEVFLSYVNGKFCLA"
                     /name="IS30 family transposase"
     gene            27257..28732
                     /locus_tag="XM37_RS14785"
                     /old_locus_tag="XM37_15095"
     CDS             27257..28732
                     /locus_tag="XM37_RS14785"
                     /old_locus_tag="XM37_15095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-directed DNA polymerase"
                     /protein_id="WP_000443455.1"
                     /translation="MESFVSLNLTNNTSKKNQPKDIKDIVDTRMYKERDDLNYTLIINK
                     DGNYSWRPLVLLHPILYVDLVNCLTKEDHWEELKKRFSEFKKDKNINCYSIPVEASKGS
                     KRTDLGETILNWWEYFEQKSLAQNIKYQYCMFTDIADCYPSIYTHSITWAMYGKEKVKN
                     DENKCSGSLGDKIDKKISGMQHNQTNGIPQGSVLMDFVAEIVLGYVDLRLSKELKKLEN
                     LKDYKVLRYRDDYRIFSNNRNDLEQIMKVLSEVLYDLNFKLNSSKTKLSDDIIIDSIKK
                     DKLYWEEIKASIRMNATNLDGDREIRYSINLQKHLLEIKKLADKHPNSGQLKKALSEFN
                     KERIIKITSKPNDLLPLIGILVDIMINNPGSLPQCVLIIGQLLNFENESKAREIVEMII
                     NKYALKPNTEFMMIWFQRLTTIFGEMFDSVLSSEFVSKIKDPVSNQMFSVDWLNEDAKK
                     SFYEGTIKDEEKYIKMSKKIYITEFDDFNDYPF"
                     /name="RNA-directed DNA polymerase"
     gene            29070..>30533
                     /locus_tag="XM37_RS14790"
                     /old_locus_tag="XM37_15100"
                     /pseudo=""
     CDS             29070..>30533
                     /locus_tag="XM37_RS14790"
                     /old_locus_tag="XM37_15100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305144.1"
                     /GO_function="GO:0015666 - restriction
                     endodeoxyribonuclease activity [Evidence IEA]; GO:0009007 -
                     site-specific DNA-methyltransferase (adenine-specific)
                     activity [Evidence IEA]"
                     /GO_process="GO:0006306 - DNA methylation [Evidence IEA];
                     GO:0009307 - DNA restriction-modification system [Evidence
                     IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit M"
                     /name="type I restriction-modification system subunit M"
     gene            complement(30571..31251)
                     /locus_tag="XM37_RS14795"
                     /old_locus_tag="XM37_15105"
     CDS             complement(30571..31251)
                     /locus_tag="XM37_RS14795"
                     /old_locus_tag="XM37_15105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            complement(31305..32564)
                     /locus_tag="XM37_RS14800"
                     /old_locus_tag="XM37_15110"
     CDS             complement(31305..32564)
                     /locus_tag="XM37_RS14800"
                     /old_locus_tag="XM37_15110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086557923.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1251 family transposase"
                     /protein_id="WP_016171138.1"
                     /translation="MSYTHLIKETLDILDLSVTFNENCLTKEKYKGQICHIYRGNLIYT
                     AQECIHCKHQIASDIVRWGTTTVRLLMNDVSEYRTYLELKKQRFKCKACQRTFVADTSV
                     AKKHCFISEKVRWSVVTRLKKNTSMTEIAAQKNLSVSSVYRIMKRFYRPLNPFRTPLPK
                     VLCFDEFKSVRGVSGAMSFIMMDGQTQRLLDIVENRQLPFLKRYFSHFSREIREAVEWI
                     VIDMYAPYVSLVKKLFPKAQLIIDRFHIVQHIGRTFRNHRIKETNQLLKSKEQKHYQLG
                     KQLKRYWKLLQKDERKLDYTRRLWRPGFKAHLTETDIVDRLLKGSPALRVGYQLYQDFL
                     YAVKERDYVSFEELLTNNIMLPEGYQTTLRTFQKFLPQIKNALQQSYSNGPLECLNNHI
                     KVLKRNAYGFRSFYGSVAKF"
                     /name="ISL3-like element IS1251 family transposase"
     gene            complement(32714..33328)
                     /locus_tag="XM37_RS14805"
                     /old_locus_tag="XM37_15115"
     CDS             complement(32714..33328)
                     /locus_tag="XM37_RS14805"
                     /old_locus_tag="XM37_15115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_010782630.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRPV
                     FQEALDYVRDQDIFIVEAIDRLGRNYDEIITSVNYLKKKNVKLIITSLPIMAEAIGNPL
                     LDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQRRL
                     VYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
                     /name="recombinase family protein"
     gene            33778..35103
                     /locus_tag="XM37_RS14810"
                     /old_locus_tag="XM37_15120"
     CDS             33778..35103
                     /locus_tag="XM37_RS14810"
                     /old_locus_tag="XM37_15120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="WP_000969590.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRAD
                     NTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNIFR
                     RYVADEDLLIYSIDESILKVTRSLNLFTTEGTRSQRRKKLAQMIQENIKEELGLIATVG
                     VGDNPLLAKLALDNEAKHNEGFVAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRLNQMG
                     IMSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQVLPRD
                     YTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLHIGTSILETRPGFSHQMKIPITDNT
                     KELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEENLDKIIDK
                     IRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGNGGIKND"
                     /name="Y-family DNA polymerase"
     gene            35096..35446
                     /locus_tag="XM37_RS14815"
                     /old_locus_tag="XM37_15125"
     CDS             35096..35446
                     /locus_tag="XM37_RS14815"
                     /old_locus_tag="XM37_15125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000568378.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRTSQNLAKEQMTTEE
                     IAEVLNAAVIKNRSVSIQKEERNAEGYYPEDIIGKILGSDELGIYVGKDKIHYDEIRHI
                     EFYQDNKWSRLE"
                     /name="hypothetical protein"
     gene            35443..35622
                     /locus_tag="XM37_RS14820"
                     /old_locus_tag="XM37_15130"
     CDS             35443..35622
                     /locus_tag="XM37_RS14820"
                     /old_locus_tag="XM37_15130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001021554.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAAA
                     GYHNFRFYIFPLYI"
                     /name="hypothetical protein"
     gene            35758..36048
                     /locus_tag="XM37_RS14825"
                     /old_locus_tag="XM37_15135"
     CDS             35758..36048
                     /locus_tag="XM37_RS14825"
                     /old_locus_tag="XM37_15135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000026576.1"
                     /translation="MSINTFVYSHPINVYIIKNLGITVEQFCELYAYPQGTVASWITRQ
                     RRIKSLPASFVYDLSLASSLNMSDVYEKLLSLEKEYDSFKIKHDKKIKKHI"
                     /name="hypothetical protein"
     gene            36416..37204
                     /locus_tag="XM37_RS14830"
                     /old_locus_tag="XM37_15140"
     CDS             36416..37204
                     /locus_tag="XM37_RS14830"
                     /old_locus_tag="XM37_15140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302898.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016887 - ATP hydrolysis activity [Evidence IEA]"
                     /GO_process="GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_000101106.1"
                     /translation="MARILSVANQKGGVSKTTTSVNLAACLKFVYGKNVLLVDIDPQGN
                     ATDNVGFDIDGTNQPTIYEVLKGEADITDAILDYKGIDVLPADIALSSAEREFTQVGSE
                     HRLKRVLQPIKDNYDYIIIDCPPSLGMLTVNAFTVSDEIIIPVEAAYFSLKGLIKLSET
                     IETVKEYTNDKLEVRGVLFTKYNKRYNISKEMTSAATEISRVIGAKIFKTYIRRTITVD
                     EAQAAGSDLINFNKPSTAEDDYKAFTEEYLKEVGDFDGRR"
                     /name="AAA family ATPase"
     gene            37191..37517
                     /locus_tag="XM37_RS14835"
                     /old_locus_tag="XM37_15145"
     CDS             37191..37517
                     /locus_tag="XM37_RS14835"
                     /old_locus_tag="XM37_15145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000796719.1"
                     /translation="MAEDNRSQAAVSRLLGNKNKKNFKSKEVEEIELTKKNISKVIKDQ
                     GSSVRTADSIRINPILMSALKYWTTIAESDKSKPDVIEDALLKSIPEEYLIEGYKLAKK
                     QNKI"
                     /name="hypothetical protein"
     ARG             17942..18906
                     /name="vanH-A"
                     /gene="vanH-A"
                     /gene_name="D-lactate dehydrogenase VanH-A"
                     /tool="amrfinderplus"
                     /drug_class="GLYCOPEPTIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             19940..20544
                     /name="vanX-A"
                     /gene="vanX-A"
                     /gene_name="D-Ala-D-Ala dipeptidase VanX-A"
                     /tool="amrfinderplus"
                     /drug_class="GLYCOPEPTIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             15066..16216
                     /name="vanS-A"
                     /gene="vanS-A"
                     /gene_name="vancomycin resistance histidine kinase VanS-A"
                     /tool="amrfinderplus"
                     /drug_class="GLYCOPEPTIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             21766..22673
                     /name="vanY-A"
                     /gene="vanY-A"
                     /gene_name="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /tool="amrfinderplus"
                     /drug_class="GLYCOPEPTIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             6743..7596
                     /name="ant(6)-Ia"
                     /gene="ant(6)-Ia"
                     /gene_name="aminoglycoside nucleotidyltransferase
                     ANT(6)-Ia"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="99.65"
                     /coverage="94.37"
     ARG             17942..18909
                     /name="vanH gene in vanA cluster"
                     /gene="vanH gene in vanA cluster"
                     /gene_name="vanH; glycopeptide resistance gene cluster"
                     /tool="rgi"
                     /drug_class="glycopeptide antibiotic"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             19940..20547
                     /name="vanX gene in vanA cluster"
                     /gene="vanX gene in vanA cluster"
                     /gene_name="vanX; glycopeptide resistance gene cluster"
                     /tool="rgi"
                     /drug_class="glycopeptide antibiotic"
                     /identity="99.5"
                     /coverage="100.0"
     ARG             22830..23314
                     /name="vanZ gene in vanA cluster"
                     /gene="vanZ gene in vanA cluster"
                     /gene_name="vanZ; glycopeptide resistance gene cluster"
                     /tool="rgi"
                     /drug_class="glycopeptide antibiotic"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             21766..22676
                     /name="vanY gene in vanA cluster"
                     /gene="vanY gene in vanA cluster"
                     /gene_name="vanY; glycopeptide resistance gene cluster"
                     /tool="rgi"
                     /drug_class="glycopeptide antibiotic"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             15078..16219
                     /name="vanS gene in vanA cluster"
                     /gene="vanS gene in vanA cluster"
                     /gene_name="vanS; glycopeptide resistance gene cluster"
                     /tool="rgi"
                     /drug_class="glycopeptide antibiotic"
                     /identity="99.74"
                     /coverage="98.96"
     ARG             14393..15087
                     /name="vanR gene in vanA cluster"
                     /gene="vanR gene in vanA cluster"
                     /gene_name="glycopeptide resistance gene cluster; vanR"
                     /tool="rgi"
                     /drug_class="glycopeptide antibiotic"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             7597..8138
                     /name="SAT-4"
                     /gene="SAT-4"
                     /gene_name="streptothricin acetyltransferase (SAT)"
                     /tool="rgi"
                     /drug_class="nucleoside antibiotic"
                     /identity="99.44"
                     /coverage="100.0"
     ARG             6740..7599
                     /name="aad(6)"
                     /gene="aad(6)"
                     /gene_name="ANT(6)"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="100.0"
                     /coverage="103.62"
     ARG             2692..3428
                     /name="ErmB"
                     /gene="ErmB"
                     /gene_name="Erm 23S ribosomal RNA methyltransferase"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; lincosamide antibiotic;
                     streptogramin antibiotic; streptogramin A antibiotic;
                     streptogramin B antibiotic"
                     /identity="98.37"
                     /coverage="98.79"
     Typing          2..1041
                     /name="rep_cluster_889"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 atgaatgatt ttaattatta caaatcaaaa gaaatttatc gtgaaaaata ttatcaaatg
       61 cctaaggtat tttttactaa cgaaaaatac atggatctat caaatgatgc aaaaattgct
      121 tatatgctac ttaaagatcg atttgattat tcagtcaaaa ataactgggt agattctgat
      181 gataatatat ttttcatatt cacagttgaa gaattaatga aattgttaca atgccgcgaa
      241 ggtaaagtat ctaaaatcaa aaaggaatta gaaaaagcag gtcttctgaa acagaagaga
      301 ggaagagtaa ataaacgtga cggtaagatt gaatccatgc ctaatttatt gtacttaggc
      361 aagccagaag taacgaatca agacgtcttt aaaatcatgg aagaggaaga caatactgat
      421 accaccgtaa ttgcgaaaat cgcaaatacg gcaaaaccgc gagaaatcaa tgataccacc
      481 gtaattgcga aaatcgcaaa tacggcaaaa tccagtcata tcaaggactc aaccgtaatt
      541 gcgaaaatcg cagacaatct attctattct aattctatag acactaatag acacataata
      601 gacactgaaa ctgatcagtt acaaaatcaa gttttactag ataacttcgt cgacatcatg
      661 aaagaggaca gtataaatac atttgtacca gaaaatgtat taaacttgat aaaaacattt
      721 tctagtactt acgaagacgc tcaaaaaacc gtccaaacta ttcataatgc aaagaaaaaa
      781 gctgaagaat tagagcaaac agttgttgtt tatgaagaac tggaatctta tggaattgat
      841 gctgacaaag gattatatat gactttgctg aaagcttatc aaaaacaaaa aactgaaaaa
      901 gtaaacaatt tgcagaatct aattttcgtt tatgtaaaaa attggtttgt cgaaaaagct
      961 attgcggcaa agcttgcaaa cgaacaaaga gaaacattta acgaattacc aacagttagt
     1021 acggaaaatt ggctagagta gttgataaaa agcgatcact ataaaaatga tcaattttaa
     1081 attagaactt ttttatgatt ttaattttat tacaaatgtt acaaataaat agctattatt
     1141 ccggagtttt tagattaaaa gtttatgaaa acaatcacaa acgtaggttt taaagtcata
     1201 atcgttagat attttagtta tttttcattc aaaaaaatag ggaactagtg tttgcatatg
     1261 tgcttttttg agttataata attcatgaag agaggtaatt cacttatttc cccaagctga
     1321 aaagcctgat attacttctt ttcaggcagt gctgctaata ttcaattaca cttttttgta
     1381 tatttttagt tgttttaaat ttaattgtct gatatgcttg tgatgaattg attttcgttc
     1441 tgcacttttg gacgataaat tgtgataatt gaaaatacaa aaaaaagaaa ggcccctgta
     1501 aggctcggga gactggtaat ctccgtcagt gtcctacagg aaagcattaa gatgacgcct
     1561 taatgcgtgc ccttcagtgt tacggtatta cccgcaacgg acggttctgt tgcaaagttt
     1621 taaataaaga ataaaatccc ttacggtatc tatgatttaa gctgggattc ccaataatac
     1681 cttgatttca gtacagaccg aaaacccgaa gagagtgcct tcttttcggg ttttcttata
     1741 taatcctcga atggcttcca tgcctttaat cgtggtagag gcagtgcgta aacttcgata
     1801 taatttattg cgtctcttta ctggacgatg gtcttgttca atcaaattat tcaggtattt
     1861 aatggtacga tgttctgtcc cttgataaaa gccgtattct tttagtttct taaaggcact
     1921 tgtaatagag ggggctttat ctgtgactac aaccttcggt tcatcaaact gcttcactaa
     1981 ccgcttaaga aaagcatagg ctgcttgtgt gtcccgtttt ttacgtaacc aaatatccaa
     2041 ggttaaacca tctgcaccga tggctcgata caaataatgc cattttcctt taattttgat
     2101 gtacgtttca tccattttcc atgaataaaa ggatttttta tttttctttt tccaaatttg
     2161 atagagtagt ttgccatatt cttgcaccca acgataaatc gtcgtatgag aaacgttaat
     2221 gccacgatca tataagattt cttgaacttc acgatagcta aggttataac gaagatagta
     2281 gcccacggct acaataatca catcctgctg aaattgcttt cctttaaaat gattcatcgt
     2341 cattcctcct gctatctttt tctattattc taccttattt gatagtagat ttaaaacttt
     2401 gcaacagaac cattttgtgt ataataggaa ttgaagttaa attagatgct aaaaatttgt
     2461 aattaagaag gagggattcg tcatgttggt attccaaatg cgtaatgtag ataaaacatc
     2521 tactgttttg aaacagacta aaaacagtga ttacgcagat aaataaatac gttagattaa
     2581 ttcctaccag tgactaatct tatgactttt taaacagata actaaaatta caaacaaatc
     2641 gtttaacttc tgtatttatt tacagatgta ataacttcag gagtgattac atgaacaaaa
     2701 atataaaata ttctcaaaac tttttaacga gtgaaaaagt actcaaccaa ataataaaac
     2761 aattgaattt aaaagaaacc gataccgttt acgaaattgg aacaggtaaa gggcatttaa
     2821 cgacgaaact ggctaaaata agtaaacagg taacgtctat tgaattagac agtcatctat
     2881 tcaacttatc gtcagaaaaa ttaaaactga acattcgtgt cactttaatt caccaagata
     2941 ttctacagtt tcaattccct aacaaacaga ggtataaaat tgttgggagt attccttacc
     3001 atttaagcac acaaattatt aaaaaagtgg tttttgaaag ccatgcgtct gacatctatc
     3061 tgattgttga agaaggattc tacaagcgta ccttggatat tcaccgaaca ctagggttgc
     3121 tcttgcacac tcaagtctcg attcagcaat tgcttaagct gccagcggaa tgctttcatc
     3181 ctaaaccaaa agtaaacagt gtcttaataa aacttacccg ccataccaca gatgttccag
     3241 ataaatattg gaagctatat acgtactttg tttcaaaatg ggtcaatcga gaatatcgtc
     3301 aactgtttac taaaaatcag tttcatcaag caatgaaaca cgccaaagta aacaatttaa
     3361 gtaccgttac ttatgagcaa gtattgtcta tttttaatag ttatctatta tttaacggga
     3421 ggaaataatt ctatgagtcg cttttttaaa tttggaaagt tacacgttac taaagggaat
     3481 ggagataaat tattagatat actactgaca gcttccaaga agctaaagag gtccctagcg
     3541 cctacgggga atttgtatcg ataaggggta caaattccca ctaagcgctc gggacccctt
     3601 gtaggaaaat gtcctaagtg tggcaacaat attgtattaa aaaaatcgtt ttatggttgt
     3661 tcaaattatc ctgaatgtaa gtttacttta gctgaacatt ttagaaagaa aaaactaacc
     3721 aaaacgaatg taaaagaatt actggaggga aaagaaaccc tggtaaaagg aatcaaaaac
     3781 aaagagaaaa agccctacaa tgccgttgta aaaattgggg aaaagggata tattgatttt
     3841 atctcttttt caaaataaac atggggctga cccaaaagta gctcctatat gaaaaataga
     3901 ggtctttcca tttagatagt agtggaaaga cctctattta tcttttgaaa gtgaatacaa
     3961 aaataaagca cactctgcta taatataggt gattaatcca tttgagagag gtgctttatc
     4021 atgtatcaaa attataccat aaaccaactt tgtttgccta tagatcttga aattaaatta
     4081 gaagaaaatg attttgctca tgccattgtg cagtttgttg actctattcc cgatgaagtc
     4141 tttcttcctt attatcaatc tatgggtaga ccccaatatc atcctcgtat gctactttcc
     4201 attattcttt gtgcctatat tcaaggggtt tattcgggcc gccaaataca aaatatgctg
     4261 atagatagta ttcggatgcg ctacttatct caagagcaat tccctaactt tcgtactatt
     4321 aatcgttttc gcgttcatcc gattatgaac gatattctag atcattcatt tgttcaattt
     4381 cgtgagctac tggttcaaag tggcttaatc agtggcagtg ctctatacat tgatggtaca
     4441 aaaattgaag cggatgcgaa taaatactct ttcgtttgga aaaaaagtat tttaaagtat
     4501 aaggatagcc ttgatcaaaa agcccttgaa aactaccaac aaatggtgga aacaaaaatc
     4561 ttacctgagt taatagatga tttaaaggat gaactttcta tagaagagat tgaaaggatt
     4621 cgtcaatctt tggaagaaaa ggaaaatcaa ttaattgaag cgattgacca aaccgaaaca
     4681 gtagaagggg gctgacccat tattaataag gagtggacaa catgattgat gtaaatgagc
     4741 tattggaaga agctattaga gaaactgaaa atctaaatga tggcgaagtt tttcttgtta
     4801 aagatttatt caagggatat gtggggaata ggatacccag aaaggatcga cttctgcttg
     4861 gaacgttatt tttaaaccat gttagcaaaa tgaatggtaa tttaaaggct attgaaaaga
     4921 cttcatctaa tcagcagagg tataaaaaga caattgataa gttttaacta tcttttgtga
     4981 aattaaaaaa attataaata tgttgagtag aagcaaaaga tttggcttgg aatttttaca
     5041 gcagtgaatc gataaaagga gcatgcttga tggtagataa tattattaaa tcagtagcag
     5101 agaaattatc ctctctgtct tatatagaag gtattgtttt aggtggttca cgtgcaaggg
     5161 gcacccatac agaggattcg gatatagata tcggcatcta ttacaattca gaatcatttg
     5221 acataaatac tattaatcaa ttcgctacaa agctggatga tgagcataga aataaccttg
     5281 ttgtacctcc cggagcatgg ggtgattgga ttaatggcgg cggatggtta gtcataaacg
     5341 ggtatcatgt ggatttaatt ttacgtgata ttaaacgtgt ggaacaaata atgaaagata
     5401 cagagcacgg aattgttact gccaattatc agactgggca tccccatggt tatattagtg
     5461 caatgtatcg aggagaatta gcgattagca aaatactata tgctaagaat gaaagcttat
     5521 gcgaattaaa aaaacaggca gaaacttatc ccaatgcttt gcagaaaagt ttagttaact
     5581 tttttatgtt tgaagcaggg ttctctttaa tgtttgtaaa agcaaattcg ggaacagacg
     5641 ataaatatta tattgcgggt catgtttttc gtatagtttc atgtttaaat caagtgttat
     5701 ttgcatgtaa taatgcttat tgtatcaacg aaaagaaagc tataaaactg cttgaaactt
     5761 ttgaacataa acctgaaaaa tataccgaga aggtaaatca tatttttgaa gtactcggta
     5821 tctcactttt tgaatgctac gacatgaccg agaagcttta taatgaagtg aatgaaattg
     5881 tatcggagat aaataacttt ttaaacgagg agagttcaga tgaaagaaaa caaatatgat
     5941 gataatatat tttttcaaaa atacagtcaa atgagtcgct cgcagaaagg actggctggt
     6001 gcgggagaat gggagacttt gaaaaagatg ctacctgatt ttaagggtaa gcgtgtgctt
     6061 gatttaggat gcggctatgg atggcactgt atatatgcga tggaaaacgg tgcttcctct
     6121 gtagtaggtg ttgatatttc tcataaaatg ctcgaagtag caaaaggaaa aacccatttt
     6181 ccacagattg aatatgaatg ctgtgccata gaagatgtgg atttcccaga ggagagcttt
     6241 gatgtaatac taagttcgct tgcgtttcat tatgtagcag actatgagaa tttaataaaa
     6301 aagatatata ggatgctgaa ggctggtggc aatttagttt ttacagttga acatcctgtt
     6361 tttactgctc atggaacaca agactggtat tataacgaaa aaggagaaat actgcatttc
     6421 ccggtggaca attattatta tgagggcaaa cggacagcta tgtttttgga agaaaaggtt
     6481 acaaaatatc atagaacact gaccacatat ctaaatacac tgctttcaaa tagttttata
     6541 ataaatcaga ttgtggagcc acagccgcca gagaacatga tggatattcc ggggatggcg
     6601 gatgaaatgc gacgcccaat gatgctgatt gtatcggcaa aaaagaagat gtaataatat
     6661 agaaaaaata aacgaggagt atgtaaatga gatcagaaaa agaaatgatg gatttagtac
     6721 tttctttagc agaacaggat gaacgaacgt attcgaattg tgacccttga ggggtcacgc
     6781 gcaaatatta atatacctaa agatgaattt caggattatg atattacata ttttgtaagt
     6841 gatatagaac cgtttatatc taatgatgac tggcttaatc aatttgggaa tataataatg
     6901 atgcaaaagc cggaggatat ggaattattc ccacctgaag aaaagggatt ttcctatctt
     6961 atgctatttg atgattacaa taaaattgat cttaccttat tgcccttgga agagttagat
     7021 aattacctaa agggcgataa attaataaag gttctaattg ataaagattg tagaattaaa
     7081 agggacatag ttccgactga tatagattat catgtaagaa agccaagcgc aagggagtat
     7141 gatgattgct gcaatgaatt ttggaatgta acaccttatg ttattaaagg attgtgccgt
     7201 aaggaaattt tatttgctat tgatcatttt aatcagattg ttcgccatga gctgctgaga
     7261 atgatatcat ggaaggtcgg catcgaaaca ggctttaaat taagtgtagg caagaactat
     7321 aagtttattg aaaggtatat atccgaggat ttgtgggaga aacttttgtc cacctaccgg
     7381 atggattcct atgaaaacat atgggaagca ttatttctat gccatcaatt gttcagggcg
     7441 gtatccggtg aggtggcgga aaggcttcat tatgcctatc cggagtatga taggaatata
     7501 acaaaatata ccagggacat gtataaaaaa tacactggta aaaccggctg cctggatagc
     7561 acatatgccg ctgatataga agagaggcgg gaacagtgat tacagaaatg aaagcagggc
     7621 acctgaaaga tatcgataaa cccagcgaac catttgaggt gataggtaag attataccga
     7681 ggtatgaaaa cgagaattgg acctttacag aattactcta tgaagcgcca tatttaaaaa
     7741 gctaccaaga cgaagaggat gaagaggatg aggaggcaga ttgccttgaa tatattgaca
     7801 atactgataa gataatatat ctttactacc aagacgataa atgcgtcgga aaagttaaac
     7861 tgcgaaaaaa ttggaaccgg tacgcttata tagaagatat cgccgtatgt aaggatttca
     7921 gggggcaagg cataggcagc gcgcttatca atatatctat agaatgggca aagcataaaa
     7981 acttgcatgg actaatgctt gaaacccagg acaataacct tatagcttgt aaattctatc
     8041 ataattgtgg tttcaaaatc ggctccgtcg atactatgtt atacgccaac tttgaaaaca
     8101 actttgaaaa agctgttttc tggtatttaa ggttttagaa tgcaaggaac agtgaattgg
     8161 agttcgtctt gttataatta gcttcttggg gtatctttaa atactgtaga aaagaggaag
     8221 gaaataataa atggctaaaa tgagaatatc accggaattg aaaaaactga tcgaaaaata
     8281 ccgctgcgta aaagatacgg aaggaatgtc tcctgctaag gtatataagc tggtgggaga
     8341 aaatgaaaac ctatatttaa aaatgacgga cagccggtat aaagggacca cctatgatgt
     8401 ggaacgggaa aaggacatga tgctatggct ggaaggaaag ctgcctgttc caaaggtcct
     8461 gcactttgaa cggcatgatg gctggagcaa tctgctcatg agtgaggccg atggcgtcct
     8521 ttgctcggaa gagtatgaag atgaacaaag ccctgaaaag attatcgagc tgtatgcgga
     8581 gtgcatcagg ctctttcact ccatcgacat atcggattgt ccctatacga atagcttaga
     8641 cagccgctta gccgaattgg attacttact gaataacgat ctggccgatg tggattgcga
     8701 aaactgggaa gaagacactc catttaaaga tccgcgcgag ctgtatgatt ttttaaagac
     8761 ggaaaagccc gaagaggaac ttgtcttttc ccacggcgac ctgggagaca gcaacatctt
     8821 tgtgaaagat ggcaaagtaa gtggctttat tgatcttggg agaagcggca gggcggacaa
     8881 gtggtatgac attgccttct gcgtccggtc gatcagggag gatatcgggg aagaacagta
     8941 tgtcgagcta ttttttgact tactggggat caagcctgat tgggagaaaa taaaatatta
     9001 tattttactg gatgaattgt tttagtacct agatttagat gtctaaaaag ctttaactac
     9061 aagcttttta gacatctaat cttttctgaa gtacatccgc aactgtccat actctgatgt
     9121 tttatatctt ttctaaaagt tcgctagata gagttctata ttagagatgt aaagagtttt
     9181 ggtgaagagg tttgtgagta tggcttttat aaccagggtg caatgagaag cactaacagc
     9241 agctagctta agaacgcata ggatatactt tttatggaag tcacagagga ggaataaaat
     9301 ttgaacagga ttaacagagt aacctctatt cttattcagc tgcaatcaaa aaaaataatt
     9361 cctgccaaag aaattgcaca gcgatttaat ataagcttaa ggacagttta cagagatatc
     9421 cggacacttg aagaagccgg aataccaatt ggatctgagg ccggaaaagg atattttctt
     9481 gtagagggct tcctacttcc gccggtaatg tttacagcgg cggaagtggg tgcattgatt
     9541 acagcaggga aatttttaaa ttgccatgga gatgaatcat ttataaagga ttttgattca
     9601 gctatgtata aaatcaaatc tattttgaag catggtgaaa aaaactatgc acaggagttg
     9661 gagaacagta ttaacgtgta cagcacatct ggacagaaaa atacattggc ggataacgtt
     9721 attgcagcaa ttcagactgc aatctgcaat aaaagggtaa ggttctgttg caaagtttta
     9781 aataaagaat aaaatccctt acggtatcta tgatttaagc tgggattccc aataatacct
     9841 tgatttcagt acagaccgaa aacccgaaga gagtgccttc ttttcgggtt ttcttatata
     9901 atcctcgaat ggcttccatg cctttaatcg tggtagaggc agtgcgtaaa cttcgataga
     9961 atttattgcg tctctttact ggacgatggt cttgttcaat caaattattc aggtatttaa
    10021 tggtacgatg ttctgtccct tgataaaagc cgtattcttt tagtttctta aaggcacttg
    10081 taatagaggg ggctttatct gtgactacaa ccttcggttc atcaaactgc ttcactaacc
    10141 gcttaagaaa agcataggct gcttgtgtgt cccgtttttt acgtaaccaa atatccaagg
    10201 ttaaaccatc tgcatcgatg gctcgataca aataatgcca ttttccttta attttgatgt
    10261 acgtttcatc cattttccat gaataaaagg attttttatt tttctttttc caaatttgat
    10321 agagtagttt gccatattct tgcacccaac gataaatcgt cgtatgagaa acgttaatgc
    10381 cacgatcata taagatttct tgaacttcac gatagctaag gttataacga agatagtagc
    10441 ccacggctac aataatcaca tcctgctgaa attgctttcc tttaaaatga ttcatcgtca
    10501 ttcctcctgc tatctttttc tattattcta ccttatttga tagtagattt aaaactttgc
    10561 aacagaaccc tgttcaaaat ctaaaatcaa cacatcatgg ggagtgtgat aataaatatt
    10621 ttcccttaat gtaccaacaa tggtaattcg gtcaattgac cattgcattt ttaagggggt
    10681 gcacatagtt tgtgcattta accgcctgtt agaaatacgg ttaagttttt cccactcatt
    10741 tacgattatg ccttttttac tcaaaaatag ctcctcctca acgaaaaaag agattcttgg
    10801 aaagaatttc cagagttcac gtaactctaa aaatccacat ccaaaaatct ctagcttgaa
    10861 gaaacctaaa aatattcgta taatgaactt gagttacgga actaggtgaa gtagtttccg
    10921 taaaggtcga gagtgcgtca acactgctcg actatttttt tactcttttt tctcattttc
    10981 tttgattata gcactcctct agaaaaaata aaaagacctc agggaatttc attccccgaa
    11041 ccccttgagc ctcctcctgc cgaaatagaa tggcgctgcc agcatttatt tcgttcagct
    11101 atcggctaca caatctaaca cgaccgttcc gctaccagtc gccttacagg ctccattttc
    11161 gctcctctaa cgtgtttcac cgattgtgcc gataactaaa cgaaataaac gctaaaaccg
    11221 ctcagaacgc aaaatatgcc attttagagc tattgtagaa aatatagttt gaaatgcaat
    11281 tttcttcttt cagcttttta tttcccactt gtaaatcggt agatggtggc tccttttcca
    11341 gttccataat gtggatttgc atctgcatgt agtgatgaaa cacctagctg cattctcata
    11401 ccatctgacg aagatgttgt accgtcgccc caatagaaag gcaattgtaa tttatgatga
    11461 aagtttacta atatggcttg ggctttattc atggcatctt catacatgcg ccattgagat
    11521 acattggcta gttgcttata tgtaagtccg ggtgtggctt cggccatctt gctcaagcca
    11581 atattcattc ccattcctaa aagggcagcc atgataatga ttgtttcttc cttatctggt
    11641 tttcgattat tggaagcatg agtgaattgc tcatgaaatc ctgttatatg ggccacatcc
    11701 atgagtaaat cagttaattt tattcttggt agcatctgat aaaggcttgc actaaatttt
    11761 tttgcttctt ctggaacatc tttttctaag cgtgcaagtg atagctttcc tttttcaaga
    11821 gaaaccccat ctaacttatt ggaattggca gctaaccact ttaacctttc attaaagctg
    11881 ctggttctct ccgttatata atcttcgaat gataaactaa ctgataatct cgtattcccc
    11941 ttcgattgat tccatgtatc ttccgaaaac aaatattcct caaaatccct atattgtctg
    12001 ctgccaacaa tggaaacatc tcctgcccga acatgctccc gaagttctgt taaaacagcc
    12061 atttcatagt aatgacgatt aattgttgta ccatcatcct cgtataaatg tcttttccat
    12121 cgttttgaaa taaaatccac aggtgagtca tcaggcactt ttcgctttcc agattcgttc
    12181 attcctcgga taatctcaac agcttgtaaa agtggctcat ttgcctttgt agaatgaaat
    12241 tccaatactc ttaatagcgt tggcgtatat tttcttagtg aataaaaccg tttttgcagt
    12301 aagtctaaat aatcatagtc ggcaggacgt gcaagttcct gagcctcttc tactgaagag
    12361 acaaaggtat tccattcaat aaccgattct aaaaccttaa aaacgtctaa tttttcctct
    12421 cttgctttaa ttaatgcttg tccgatgttc gtaaagtgta taactttctc atttagcttt
    12481 ttaccgtttt gtttctggat ttcctcttga gccttacgac cttttgataa caaactaagt
    12541 atttgcctat catgaatttc aaacgcttta tccgttagct cctgagtaag ttgtaataaa
    12601 tagatggtta atatcgaata acgtttattt tcttgaaagt cacggaatgc atacggctcg
    12661 tatcttgagc ctaagcgaga cagctgcaac aggcggttac ggtgcaaatg actaatttgc
    12721 actgtttcta aatccattcc tcgtatgtat tcgagtcgtt ctattatttt tagaaaagtt
    12781 tcgggtgaag gatgacccgg tggctctttt aaccaaccca atatcgtttt attggattcg
    12841 gatggatgct gcgaggtaat aatcccttca agcttttctt tttgctcatt tgttagagat
    12901 ttactaaccg tattaaatag cttcttttca gccattgccc ttgcttccca caccattctt
    12961 tcaagtgtag tgatagcagg cagtataatt ttgttttttc ttagaaaatc tatgcattca
    13021 tgcagtagat gaatggcatc accattttcc aaagctaatt gatgaaggta cttaaatgtc
    13081 attcgatatt cactcagggt aaaagttaca aagtcgtatt cacttcgaat ttctttcaaa
    13141 tgatcccaaa gtgtattttc cctttgagga taatgatcaa gcgaggatgg actaacacca
    13201 atctgtttcg atatatattg tatgaccgaa tctgggatgc ttttgatatg agtgtatggc
    13261 caaccgggat accgaagaac agctaattga acagcaaatc ctaaacggtt ttcttccctc
    13321 cttcgcttat taactatttc taaatcccgt ttggaaaaag tgaagtaggt ccccagtatc
    13381 cattcatctt cagggatttg cataaaagcc tgtctctgtt ccggtgtaag caattctcta
    13441 cctctcgcaa ttttcattca gtatcattcc atttctgtat tttcaattta ttagttcaat
    13501 tatatatcaa tagagtgtac tctattgata caaatgtagt agactgataa aatcatagtt
    13561 aagagcgtct cataagactt gtctcaaaaa tgaggtgata ttttgcggaa aatcggttat
    13621 attcgtgtca gttcgactaa ccagaatcct tcaagacaat ttcagcagtt gaacgagatc
    13681 ggaatggata ttatatatga agagaaagtt tcaggagcaa caaaggatcg cgagcaactt
    13741 caaaaagtgt tagacgattt acaggaagat gacatcattt atgttacaga cttaactcga
    13801 atcactcgta gtacacaaga tctatttgaa ttaatcgata acatacgaga taaaaaggca
    13861 agtttaaaat cactaaaaga tacatggctt gatttatcag aagataatcc atacagccaa
    13921 ttcttaatta ctgtaatggc tggtgttaac caattagagc gagatcttat tcggatgaga
    13981 caacgtgaag ggattgaatt ggctaagaaa gaaggaaagt ttaaaggtcg attaaagaag
    14041 tatcataaaa atcacgcagg aatgaattat gcggtaaagc tatataaaga aggaaatatg
    14101 actgtaaatc aaatttgtga aattactaat gtatctaggg cttcattata caggaaatta
    14161 tcagaagtga ataattagcc attctgtatt ccgctaatgg gcaatatttt taaagaagaa
    14221 aaggaaacta taaaatatta acagcctcct agcgatgccg aaaagccctt tgataaaaaa
    14281 agaatcatca tcttaagaaa ttcttagtca tttattatgt aaatgcttat aaattcggcc
    14341 ctataatctg ataaattatt aagggcaaac ttatgtgaaa gggtgataac tatgagcgat
    14401 aaaatactta ttgtggatga tgaacatgaa attgccgatt tggttgaatt atacttaaaa
    14461 aacgagaatt atacggtttt caaatactat accgccaaag aagcattgga atgtatagac
    14521 aagtctgaga ttgaccttgc catattggac atcatgcttc ccggcacaag cggccttact
    14581 atctgtcaaa aaataaggga caagcacacc tatccgatta tcatgctgac cgggaaagat
    14641 acagaggtag ataaaattac agggttaaca atcggcgcgg atgattatat aacgaagccc
    14701 tttcgcccac tggagttaat tgctcgggta aaggcccagt tgcgccgata caaaaaattc
    14761 agtggagtaa aggagcagaa cgaaaatgtt atcgtccact ccggccttgt cattaatgtt
    14821 aacacccatg agtgttatct gaacgagaag cagttatccc ttactcccac cgagttttca
    14881 atactgcgaa tcctctgtga aaacaagggg aatgtggtta gctccgagct gctatttcat
    14941 gagatatggg gcgacgaata tttcagcaag agcaacaaca ccatcaccgt gcatatccgg
    15001 catttgcgcg aaaaaatgaa cgacaccatt gataatccga aatatataaa aacggtatgg
    15061 ggggttggtt ataaaattga aaaataaaaa aaacgactat tccaaactag aacgaaaact
    15121 ttacatgtat atcgttgcaa ttgttgtggt agcaattgta ttcgtgttgt atattcgttc
    15181 aatgatccga gggaaacttg gggattggat cttaagtatt ttggaaaaca aatatgactt
    15241 aaatcacctg gacgcgatga aattatatca atattccata cggaacaata tagatatctt
    15301 tatttatgtg gcgattgtca ttagtattct tattctatgt cgcgtcatgc tttcaaaatt
    15361 cgcaaaatac tttgacgaga taaataccgg cattgatgta cttattcaga acgaagataa
    15421 acaaattgag ctttctgcgg aaatggatgt tatggaacaa aagctcaaca cattaaaacg
    15481 gactctggaa aagcgagagc aggatgcaaa gctggccgaa caaagaaaaa atgacgttgt
    15541 tatgtacttg gcgcacgata ttaaaacgcc ccttacatcc attatcggtt atttgagcct
    15601 gcttgacgag gctccagaca tgccggtaga tcaaaaggca aagtatgtgc atatcacgtt
    15661 ggacaaagcg tatcgactcg aacagctaat cgacgagttt tttgagatta cacggtataa
    15721 cctacaaacg ataacgctaa caaaaacgca catagaccta tactatatgc tggtgcagat
    15781 gaccgatgaa ttttatcctc agctttccgc acatggaaaa caggcggtta ttcacgcccc
    15841 cgaggatctg accgtgtccg gcgaccctga taaactcgcg agagtcttta acaacatttt
    15901 gaaaaacgcc gctgcataca gtgaggataa cagcatcatt gacattaccg cgggcctctc
    15961 cggggatgtg gtgtcaatcg aattcaagaa cactggaagc atcccaaaag ataagctagc
    16021 tgccatattt gaaaagttct ataggctgga caatgctcgt tcttccgata cgggtggcgc
    16081 gggacttgga ttggcgattg caaaagaaat tattgttcag catggagggc agatttacgc
    16141 ggaaagcaat gataactata cgacgtttag ggtagagctt ccagcgatgc cagacttggt
    16201 tgataaaagg aggtcctaag agatgtatat aattttggct ctttgtcaaa tgatgttggt
    16261 aaagagaaat cttagaataa ttggagatca agtggatcag ttcctcttga tcttttttag
    16321 ttgaaaatca atgcgttgcc atgacgaatc atgatgcgca atttgaaatt ataaaagcta
    16381 cgaaagccat atgcatttcg ttttaacact ttgatatggt tgttcagaca ttcaagtggg
    16441 ccatttgaat aactttgttg taaagcattt ttgatttgtg gcagaaattt ctggaacgtt
    16501 ctcaaggtcg tctgatagcc ttcgggaagc atgatattat tggtaagtag ttcttcaaac
    16561 gatacgtagt ctcgttcctt tacagcgtaa agaaagtctt gatataactg atagcctaca
    16621 cgcaaagcag ggctcccttt cagtaagcga tccacaatat cggtctctgt taaatgagct
    16681 ttgaagccag gtcgccaaag gcgtcgagta taatcaagct tgcgttcatc tttttgaaga
    16741 agtttccagt atctttttaa ttgcttacct aattgatagt gtttttgttc tttgcttttt
    16801 aatagttggt tcgtttcttt gattcgatga ttgcgaaagg tacgaccaat atgttggacg
    16861 atgtgaaacc ggtcaataat cagctgtgct tttggaaaca gctttttaac gagcgataca
    16921 taaggagcgt acatatcaat cacgatccat tcgaccgctt cacgaatttc tcgtgaaaaa
    16981 tgactaaaat aacgttttaa aaaaggcagt tgtcggttct cgacaatgtc caataagcgc
    17041 tgtgtttgtc catccatcat gatgaaactc atagcacctg aaacaccccg aactgatttg
    17101 aattcatcaa aacaaagtac cttaggtaac ggtgtccgaa aaggattcaa cggacgataa
    17161 aatcgcttca taatacggta aacagaagag accgatagat ttttctgagc ggcgatctct
    17221 gtcattgagg tatttttttt cagacgagtc acgacagacc agcggacttt ctcactgatg
    17281 aaacaatgtt ttttcgcaac agaagtatct gcgacaaagg tccgctgaca agctttgcat
    17341 ttgaagcgtt gctttttcaa ttcgaggtag gtacggtatt cagaaacatc gttcattaac
    17401 aaccggacgg ttgttgtacc ccaacgcaca atatctgaag caatctggtg tttacagtgg
    17461 atgcattctt gggctgtata aatcaagttt ccacgataaa tatgacagat ttgccctttg
    17521 tatttttctt ttgtgagaca attttcgtta aaagtaactg ataagtctag aatatctaat
    17581 gtttctttga taaggtgagt gtaagacatc ttgattcctc cttttgggtt ggttcgccaa
    17641 attaattcta aaggatttca aggtgtcttt tctatatgtt ttggaaaata aaaaagatgc
    17701 tggtgtcatc caccaacatc aaaaagtata gagccataat tttttaggaa aatctcaagg
    17761 ttatctttac tttttcttag gaaattaaca atttaatatt aagaaacggc tcgttcttac
    17821 acggtagact taataccgta agaacgagcc gttttcgttc ttcagagaaa gatttgacaa
    17881 gattaccatt ggcatccccg ttttatttgg tgcctttcac agaaagggtt ggtcttaatt
    17941 atgaataaca tcggcattac tgtttatgga tgtgagcagg atgaggcaga tgcattccat
    18001 gctctttcgc ctcgctttgg cgttatggca acgataatta acgccaacgt gtcggaatcc
    18061 aacgccaaat ccgcgccttt caatcaatgt atcagtgtgg gacataaatc agagatttcc
    18121 gcctctattc ttcttgcgct gaagagagcc ggtgtgaaat atatttctac ccgaagcatc
    18181 ggctgcaatc atatagatac aactgctgct aagagaatgg gcatcactgt cgacaatgtg
    18241 gcgtactcgc cggatagcgt tgccgattat actatgatgc taattcttat ggcagtacgc
    18301 aacgtaaaat cgattgtgcg ctctgtggaa aaacatgatt tcaggttgga cagcgaccgt
    18361 ggcaaggtac tcagcgacat gacagttggt gtggtgggaa cgggccagat aggcaaagcg
    18421 gttattgagc ggctgcgagg atttggatgt aaagtgttgg cttatagtcg cagccgaagt
    18481 atagaggtaa actatgtacc gtttgatgag ttgctgcaaa atagcgatat cgttacgctt
    18541 catgtgccgc tcaatacgga tacgcactat attatcagcc acgaacaaat acagagaatg
    18601 aagcaaggag catttcttat caatactggg cgcggtccac ttgtagatac ctatgagttg
    18661 gttaaagcat tagaaaacgg gaaactgggc ggtgccgcat tggatgtatt ggaaggagag
    18721 gaagagtttt tctactctga ttgcacccaa aaaccaattg ataatcaatt tttacttaaa
    18781 cttcaaagaa tgcctaacgt gataatcaca ccgcatacgg cctattatac cgagcaagcg
    18841 ttgcgtgata ccgttgaaaa aaccattaaa aactgtttgg attttgaaag gagacaggag
    18901 catgaataga ataaaagttg caatactgtt tgggggttgc tcagaggagc atgacgtatc
    18961 ggtaaaatct gcaatagaga tagccgctaa cattaataaa gaaaaatacg agccgttata
    19021 cattggaatt acgaaatctg gtgtatggaa aatgtgcgaa aaaccttgcg cggaatggga
    19081 aaacgacaat tgctattcag ctgtactctc gccggataaa aaaatgcacg gattacttgt
    19141 taaaaagaac catgaatatg aaatcaacca tgttgatgta gcattttcag ctttgcatgg
    19201 caagtcaggt gaagatggat ccatacaagg tctgtttgaa ttgtccggta tcccttttgt
    19261 aggctgcgat attcaaagct cagcaatttg tatggacaaa tcgttgacat acatcgttgc
    19321 gaaaaatgct gggatagcta ctcccgcctt ttgggttatt aataaagatg ataggccggt
    19381 ggcagctacg tttacctatc ctgtttttgt taagccggcg cgttcaggct catccttcgg
    19441 tgtgaaaaaa gtcaatagcg cggacgaatt ggactacgca attgaatcgg caagacaata
    19501 tgacagcaaa atcttaattg agcaggctgt ttcgggctgt gaggtcggtt gtgcggtatt
    19561 gggaaacagt gccgcgttag ctgttggcga ggtggaccaa atcaggctgc agtacggaat
    19621 ctttcgtatt catcaggaag tcgagccgga aaaaggctct gaaaacgcag ttataaccgt
    19681 tcccgcagac ctttcagcag aggagcgagg acggatacag gaaacggcaa aaaaaatata
    19741 taaagcgctc ggctgtagag gtctagcccg tgtggatatg tttttacaag ataacggccg
    19801 cattgtactg aacgaagtca atactctgcc cggtttcacg tcatacagtc gttatccccg
    19861 tatgatggcc gctgcaggta ttgcacttcc cgaactgatt gaccgcttga tcgtattagc
    19921 gttaaagggg tgataagcat ggaaatagga tttacttttt tagatgaaat agtacacggt
    19981 gttcgttggg acgctaaata tgccacttgg gataatttca ccggaaaacc ggttgacggt
    20041 tatgaagtaa atcgcattgt agggacatac gagttggctg aatcgctttt gaaggcaaaa
    20101 gaactggctg ctacccaagg gtacggattg cttctatggg acggttaccg tcctaatcgt
    20161 gctgtaaact gttttatgca atgggctgca cagccggaaa ataacctgac aaaggaaagt
    20221 tattatccca atattgaccg aactgagatg atttcaaaag gatacgtggc ttcaaaatca
    20281 agccatagcc gcggcagtgc cattgatctt acgctttatc gattagacac gggtgagctt
    20341 gtaccaatgg ggagccgatt tgattttatg gatgaacgct ctcatcatgc ggcaaatgga
    20401 atatcatgca atgaagcgca aaatcgcaga cgtttgcgct ccatcatgga aaacagtggg
    20461 tttgaagcat atagcctcga atggtggcac tatgtattaa gagacgaacc ataccccaat
    20521 agctattttg atttccccgt taaataaact tttaaccgtt gcacggacaa actatataag
    20581 ctaactcttt cggcaggaaa cccgacgtat gtaactggtt cttagggaat ttatatatag
    20641 tagatagtat tgaagaggtt ctgttgcaaa gttttaaata aagaataaaa tcccttacgg
    20701 tatctatgat ttaagctggg attcccaata ataccttgat ttcagtacag accgaaaacc
    20761 cgaagagagt gccttctttt cgggttttct tatataatcc tcgaatggct tccatgcctt
    20821 taatcgtggt agaggcagtg cgtaaacttc gatagaattt attgcgtctc tttactggac
    20881 gatggtcttg ttcaatcaaa ttattcaggt atttaatggt acgatgttct gtcccttgat
    20941 aaaagccgta ttcttttagt ttcttaaagg cacttgtaat agagggggct ttatctgtga
    21001 ctacaacctt cggttcatca aactgcttca ctaaccgctt aagaaaagca taggctgctt
    21061 gtgtgtcccg ttttttacgt aaccaaatat ccaaggttaa accatctgca tcgatggctc
    21121 gatacaaata atgccatttt cctttaattt tgatgtacgt ttcatccatt ttccatgaat
    21181 aaaaggattt tttatttttc tttttccaaa tttgatagag tagtttgcca tattcttgca
    21241 cccaacgata aatcgtcgta tgagaaacgt taatgccacg atcatataag atttcttgaa
    21301 cttcacgata gctaaggtta taacgaagat agtagcccac ggctacaata atcacatcct
    21361 gctgaaattg ctttccttta aaatgattca tcgtcattcc tcctgctatc tttttctatt
    21421 attctacctt atttgatagt agatttaaaa ctttgcaaca gaaccgcggt cattatctgc
    21481 gtgcgctgcg gcaagatagc ctgataataa gactgatcgc atagaggggt ggtatttcac
    21541 accgcccatt gtcaacaggc agttcagcct cgttaaattc agcatgggta tcacttatga
    21601 aaattcatct acattggtga taatagtaaa tccagtaggg cgaaataatt gactgtaatt
    21661 tacggggcaa aacggcacaa tctcaaacga gattgtgccg tttaagggga agattctaga
    21721 aatatttcat acttccaact atatagttaa ggaggagact gaaaatgaag aagttgtttt
    21781 ttttattgtt attgttattc ttaatatact taggttatga ctacgttaat gaagcactgt
    21841 tttctcagga aaaagtcgaa tttcaaaatt atgatcaaaa tcccaaagaa catttagaaa
    21901 atagtgggac ttctgaaaat acccaagaga aaacaattac agaagaacag gtttatcaag
    21961 gaaatctgct attaatcaat agtaaatatc ctgttcgcca agaaagtgtg aagtcagata
    22021 tcgtgaattt atctaaacat gacgaattaa taaatggata cgggttgctt gatagtaata
    22081 tttatatgtc aaaagaaata gcacaaaaat tttcagagat ggtcaatgat gctgtaaagg
    22141 gtggcgttag tcattttatt attaatagtg gctatcgaga ctttgatgag caaagtgtgc
    22201 tttaccaaga aatgggggct gagtatgcct taccagcagg ttatagtgag cataattcag
    22261 gtttatcact agatgtagga tcaagcttga cgaaaatgga acgagcccct gaaggaaagt
    22321 ggatagaaga aaatgcttgg aaatacgggt tcattttacg ttatccagag gacaaaacag
    22381 agttaacagg aattcaatat gaaccatggc atattcgcta tgttggttta ccacatagtg
    22441 cgattatgaa agaaaagaat ttcgttctcg aggaatatat ggattaccta aaagaagaaa
    22501 aaaccatttc tgttagtgta aatggggaaa aatatgagat cttttattat cctgttacta
    22561 aaaataccac cattcatgtg ccgactaatc ttcgttatga gatatcagga aacaatatag
    22621 acggtgtaat tgtgacagtg tttcccggat caacacatac taattcaagg aggtaaggat
    22681 ggcggaatga aaccaacgaa attaatgaac agcattattg tactagcact tttggggtaa
    22741 cgttagcttt ttaatttaaa acccacgtta actaggacat tgctatacta atgatacaac
    22801 ttaaacaaaa gaattagagg aaattatatt gggaaaaata ttatctagag gattgctagc
    22861 tttatattta gtgacactaa tctggttagt gttattcaaa ttacaataca atattttatc
    22921 agtatttaat tatcatcaaa gaagtcttaa cttgactcca tttactgcta ctgggaattt
    22981 cagagagatg atagataatg ttataatctt tattccattt ggcttgcttt tgaatgtcaa
    23041 ttttaaagaa atcggatttt tacctaagtt tgcttttgta ctggttttaa gtcttacttt
    23101 tgaaataatt caatttatct tcgctattgg agcgacagac ataacagatg taattacaaa
    23161 tactgttgga ggctttcttg gactgaaatt atatggttta agcaataagc atatgaatca
    23221 aaaaaaatta gacagagtta ttatttttgt aggtatactt ttgctcgtat tattgctcgt
    23281 ttaccgtacc catttaagaa taaattacgt gtaagatgtc taaatcaagc aatctgatct
    23341 ttcatacaca taaagatatt gaatgaattg gattagatgg aaaacgggat gtggggaaac
    23401 tcgcccgtag gtgtgaagtg aggggaaaac cggtgataaa gtaaaaagct tacctaacac
    23461 tatagtaaca aagaaagccc aattatcaat tttagtgctg aggaattggt ctctttaata
    23521 aatttcctta acgttgtaaa tccgcatttt cctgacggta cccccaaact aagatttcat
    23581 agatagattt tctgataact ttaaaaaaca cgaatagcgg aaaggatgtc ttcattcgct
    23641 aaagagtaat aaactacttt tccatcttga cgtgattttg ccattccatg tttttttaaa
    23701 aaacgtaaat ggtgtgacgt tgtagcgaca ctagcagtaa gtatttctgc taaatcacag
    23761 acgcacattt ccttataggt ttctaaagca tagaaaattt taattctaga aaaatcgctg
    23821 aaacatttcc ctaacacaag taagtttgaa aaatcttttt gatccaattt attttttatt
    23881 ccatttactt tttctttatg tacgacagtc acttggcaaa cttttttcat tcatctcacc
    23941 tcacattcaa acgattattt gaatgaagta tacctatttg atcactcttt tgtcaatcta
    24001 ccttaattcc aatacactat tataagcaat ttcatgtatt gaagtaaact tacttgcaag
    24061 tgcgtttttg attccaagtt aaaaacatat tattattcta cataatttcc taatcaaata
    24121 aaactccttt gaaaattgtt ctaaaggagt tttattattt tgtatttcta ctaaaaatag
    24181 cgtacaatgt aattactaag taattacgaa atgtaaaata atggaggaaa taatatgatt
    24241 acaaaaacaa gaaaacaagg aaattctatt atgttaacgg tccctaaaga attcgatgtg
    24301 cccaatggtg ttgaagtaga agctaagctt gtagagaatg gtatccttta tgagtttgta
    24361 gagcctaaaa aagaattttt tgattttagt gaagatattt tggctgatat tctttcagaa
    24421 ggttatagca aacaagagat cttaaaagaa tttagaaata gaaaaaatgc gttaacttct
    24481 gcatttaaat ctattgctga agatactgtt gcaaattcta aaccgatgac aaaagaggag
    24541 ttggcagcag aaattggctt atgagattct accttctaaa cacgtaataa agtatctaaa
    24601 aaaattaaaa gagaaaacat taaaagaaca atttttaacg ataatttatg atgagatagc
    24661 agttcgtcct cattcgggag aacaaaaaac gggtgattta tcaggaattt gggctattgg
    24721 attcaagtat gcaggtacga catatcgcgt tgcatatgaa attaaagata atgcagtgat
    24781 acctatctta ctatgtggaa cgcatgaaaa tttttatgaa caattaaaaa agattaggta
    24841 agaacccaat gtttcaactt gagaggatag acgacacttt aaaagataat ttttaacagc
    24901 tgagagttgt aataccctat aattttaaac cactaaccta tatatttatg aaaaatagaa
    24961 aaaattaaaa cgcattttaa gcctctttca aattaaaagc ttcatcctta tgcacaaaga
    25021 gggcttaaaa tgcgttattt tatattgttt tttagtaata ataaaaaaat cactctaatt
    25081 ctcccataaa tattatagat tcctaaagat taaaatagat tattccctat tgtcttttaa
    25141 gtagcggtag agtgttgcct tgctaatacc agtcatttcc gtaatttctt ttacgctata
    25201 aacctgactt ttatacaatt ttactgctcg atcaacatct ttctggttca ctcgtggacg
    25261 gccaccttta cgacctctcg cacgtgcact tttcaaacct tctttggtac gttcaacaat
    25321 taaatcacgt tcgaactgac taaatgcttg gaagacagtc atcattaagc gtccgtgagg
    25381 cgtgctggta tcgaagtttt ctttcaagct caccagctta acatggtgtt cttcaaaata
    25441 ggtaacaagg tcaatcaaat cctttgtact acgacccaat cgagaaaaac tttctacaat
    25501 taccgtatct cccggacgaa ttttatcttt taaacgattt agttggggac gaaccgcttt
    25561 ggttcccgtc attttctcag ttaggatttc attacaattt tgttcattga gtaagtctaa
    25621 ttgacgattt agttcttgtg aacgtgtact cactcgggca taaccataaa tgtatccact
    25681 catgcttttc ttcctttcgt actttaattc tggcttgatt gtatcataaa agggagttat
    25741 agatacatag ttaatgcaac aagttatgat acaaaatatg acctctttta tttaataaaa
    25801 gaggtcattt cattttgtct cataatcgat tgtttttgat acgagtgtgt atacgaaata
    25861 aacaaaaaaa tcttaagtaa atttctagat acctaattta atcctaacta gtgtatccta
    25921 aagttaataa cgagtttatc acaatgaaaa ttataaaatg ctcccatatt agatataaca
    25981 tgcaatattt gaattagaac tacaaaattt attcgtttta taaagtaaat aatgttgaga
    26041 tactaaggaa tagaatatta taaggaattg agctgaatgt attggataaa aaaagaataa
    26101 ctttattaga gatggactat aaaaatgctc gtaattttct tctgaagtct gaaagctatt
    26161 tgaatgctca gctaccagaa tatattagtt ttgacgaaac tttaaaatct gctaaaaaag
    26221 ttttaacttc gccgtttgta taattaagcg agacaaataa aaaagccatt tatgttacac
    26281 tcaaattgta atacccgcta aagcatacaa ggagagtgaa cataaatgac ttatacccat
    26341 cttacaccaa acgagcttgt aatgatagaa gcatattttc atcaagaaac tccggttgct
    26401 atcgttgcga agcagcttaa acgtggacgc caaacaattt acaatgtcta taactttctc
    26461 aaatgtggtg gaacagcact tgaatacttt gaacaataca aagaaaataa gcgacgttgt
    26521 gggagaaccg aaatcatttt tcctgctgag gaaaaagaat acattgaaaa aagatcaact
    26581 gaaggttgga ccccagacgt cattattggc cgtgcagagc gaaccttctc ttgttcaata
    26641 agtaccctct atcgccggtt taagacggga gaattcaatg ttttacattt accgatgcaa
    26701 ggaaaacgaa aaccaaatgg ttataaggaa aaacgtggaa aacaggcatt caaaagaaat
    26761 atttctgaac gtaaaaaaga ttatgtcgtt ttcgaagaag aatttggaca tttagagggt
    26821 gatacgattg tcggcatcca ccataaaagt gccgtcatca cactcgttga gcgactttca
    26881 aaagccatta tcgtcttgaa accagaaggc cgtaaggcag ttgatattga aaattcgatt
    26941 aatgaatggc ttcaatccgt acccaaaaat cttttcaaat caattacctt tgattgtgga
    27001 aaagaattct ctaattggaa aagtattagt aatacgaatg atattgatat ttatttcgca
    27061 gacccaggaa cgccttccca acggggatta aatgaacatt caaacggact cctccgaaaa
    27121 gatggactac caaaagaaat ggacttcaac caagtcaatc aaggattcat ctcatccgtt
    27181 gcgtccaaaa gaaaccatat ccctagaaaa tcactaaatt accaaacacc attagaagtt
    27241 tttttgagtt acgtaaatgg aaagttttgt ctcgcttaat ttgacaaata atacttcaaa
    27301 aaaaaaccaa ccgaaagata taaaagatat tgtagataca cgaatgtata aagaacgtga
    27361 tgacttaaac tatacgctta ttatcaataa agatggaaac tattcatggc gtcctctcgt
    27421 tctactacat cctattctat atgtagattt ggttaattgt ctcactaaag aagaccattg
    27481 ggaggagtta aaaaagaggt ttagtgaatt taaaaaagat aaaaatatta actgttattc
    27541 tatacctgtt gaagcttcca aaggttcaaa aaggacagat cttggtgaaa caatactaaa
    27601 ctggtgggaa tattttgaac aaaaaagctt agctcagaat attaaatacc aatattgcat
    27661 gtttactgac atcgctgatt gttatccatc aatttatact cactctataa catgggccat
    27721 gtatggtaaa gaaaaagtta aaaatgatga aaataagtgt tcgggctcac ttggcgataa
    27781 aatagataaa aaaatatctg gaatgcaaca caatcaaaca aatggtatcc ctcagggttc
    27841 cgttcttatg gattttgtag cagagatcgt tctagggtat gttgatttga gattatcgaa
    27901 agaattaaaa aaattagaaa atttaaaaga ttacaaagta ctcagatata gagatgatta
    27961 tagaatattt tcaaataatc gtaatgattt ggaacaaatt atgaaagtgt tatcagaagt
    28021 cttatatgat ttaaatttta agttaaattc tagtaaaaca aaattatcag atgatattat
    28081 catagattct atcaaaaaag ataagctcta ttgggaagaa attaaggcaa gtataagaat
    28141 gaatgccaca aacttagatg gtgatagaga aattcgttat agtataaatt tacaaaaaca
    28201 tttattggaa ataaaaaagt tagcagataa gcatcctaat tcaggccaat tgaaaaaagc
    28261 actttctgag tttaataaag aacgcattat taaaatcact tcaaagccga acgatctttt
    28321 accacttatt ggtatcctgg tagatatcat gataaataac ccgggttctt tgccgcagtg
    28381 tgtcttaatt atagggcagt tattaaattt cgaaaatgag agtaaggcta gagaaatagt
    28441 tgaaatgatt ataaacaaat atgctttaaa gccaaatact gaatttatga tgatatggtt
    28501 tcaaagattg accaccattt ttggagaaat gtttgatagt gttttatcat ccgaatttgt
    28561 atctaaaatc aaagatcctg tctctaatca gatgttttct gtagactggc taaatgaaga
    28621 tgctaagaaa tctttttatg aagggaccat taaagacgaa gagaaatata ttaaaatgag
    28681 taagaaaata tatattactg aatttgatga ttttaatgat tatccttttt aagtgaaaat
    28741 ttagaatgaa tataaaaaac attacaatct aattttttta aaaaaatgtt atatcggaag
    28801 taatctcttg atttctatac tataagataa gaaaaccact atttaacaag gttattcgaa
    28861 ccttatttta agttacttat tatttaatgt atcgaaaaag gtgaaatagg tttgttataa
    28921 taagaattaa gtaagacatg aattgtctaa gcaaatgtag cttatccatt tcattaaaat
    28981 acatatggtg aaaaaacaag ttcaaatagt aactaatttt ttaaaaaact gatttataaa
    29041 aaatacaaca cgaatgagga aaataaccaa tgacagaaca aatcgaaaaa aattcaaaaa
    29101 gcttatatca ggcactgtgg aattccgcag atatcctgcg ttcaaaaatg gacgctaatg
    29161 aatacaagag ctatttacta ggcttggtct tttataaata cttatccgac aacatgctgc
    29221 ggtatgtctc cgttctattg gaggaagaaa cggacgacct aaataaagca caagaccttt
    29281 acgttgaagc atttaaagat gcagatataa aggatgatct cttgtatgaa ctaaaagatg
    29341 agttttcata taccatcgca cccgcattga cctttaccgc gcaagtggca gccattcatg
    29401 atggatcttt tcaattagaa gacctggtac aaggtttccg tgacattgaa caatccagcg
    29461 aaaactttga gaacttattt gaagacattg atctgtattc taaaaaactg gggtcaaccc
    29521 cacaaaaaca aaataaaacc atcgcagatg ttatgaaaga attagaaggg ttaaacatgg
    29581 cggggcatgc tggcgatgtc ttaggcgatg cctatgagta cttaattggc caattcgcat
    29641 ctgaatccgg taaaaaagcc ggtgaattct ataccccaca accggtcgca aaattgatga
    29701 cacaaattgt tttacaagga aaagaagata aaaaaggctt ttctgtttac gacgcgacca
    29761 tgggttcggg ctcgttactt ttgaacgcta aaaaatattc ccatcaaccg ggaaccattt
    29821 cttatttcgg acaagagttg aatacgtcta cctataattt ggcgcgtatg aacatgattt
    29881 tgcatggggt tcccattgcc aaccaacact tgcataatgc ggataccttg gatcaagact
    29941 ggccaacaga agagccaacg aacttcgatg gggtgctcat gaacccaccg tattctgcaa
    30001 aatggtcggc tgataaaggc ttcttagatg acccacgctt ctctgcctat ggcgtattag
    30061 cccctaaatc aaaagcggac tttgctttct tattacatgg ctactatcat ttgaaagata
    30121 cgggcgtcat ggccattgtt ttgccacatg gggtgctctt tagagggggc gcagaaggga
    30181 agatacgcaa agccttgtta gaaaatggtg ccattgacac cgtcattggc ttacctgcta
    30241 acatcttctt taatacgtcc attccaacga ccgtaattat cttgaagaaa gaccgtgcga
    30301 aaaaagatgt gctctttatt gatgcgtcac aagattttga aaaaataaaa acgcaaaata
    30361 cgctacgaga ttaccatatt gacgctattt tagaggccta taaaacccgt acaattaaag
    30421 acaagtatgc ttatgtcgca gaatttgatg aaattgtgga gaatgattac aacttaaaca
    30481 ttccccgtta cgtggatacc tttgaagaag aagaagggtt ctgttgcaaa gttttaaata
    30541 aagaataaaa tcccttacgg tatctatgat ttaagctggg attcccaata ataccttgat
    30601 ttcagtacag accgaaaacc cgaagagagt gccttctttt cgggttttct tatataatcc
    30661 tcgaatggct tccatgcctt taatcgtggt agaggcagtg cgtaaacttc gatagaattt
    30721 attgcgtctc tttactggac gatggtcttg ttcaatcaaa ttattcaggt atttaatggt
    30781 acgatgttct gtcccttgat aaaagccgta ttcttttagt ttcttaaagg cacttgtaat
    30841 agagggggct ttatctgtga ctacaacctt cggttcatca aactgcttca ctaaccgctt
    30901 aagaaaagca taggctgctt gtgtgtcccg ttttttacgt aaccaaatat ccaaggttaa
    30961 accatctgca tcgatggctc gatacaaata atgccatttt cctttaattt tgatgtacgt
    31021 ttcatccatt ttccatgaat aaaaggattt tttatttttc tttttccaaa tttgatagag
    31081 tagtttgcca tattcttgca cccaacgata aatcgtcgta tgagaaacgt taatgccacg
    31141 atcatataag atttcttgaa cttcacgata gctaaggtta taacgaagat agtagcccac
    31201 ggctacaata atcacatcct gctgaaattg ctttccttta aaatgattca tcgtcattcc
    31261 tcctgctatc tttttctatt attctacctt atttgatagt agatttaaaa ctttgcaaca
    31321 gaaccataaa agctacgaaa gccatatgca tttcgtttta acactttgat atggttgttc
    31381 agacattcaa gtgggccatt tgaataactt tgttgtaaag catttttgat ttgtggcaga
    31441 aatttctgga acgttctcaa ggtcgtctga tagccttcgg gaagcatgat attattggta
    31501 agtagttctt caaacgatac gtagtctcgt tcctttacag cgtaaagaaa gtcttgatat
    31561 aactgatagc ctacacgcaa agcagggctc cctttcagta agcgatccac aatatcggtc
    31621 tctgttaaat gagctttgaa gccaggtcgc caaaggcgtc gagtataatc aagcttgcgt
    31681 tcatcttttt gaagaagttt ccagtatctt tttaattgct tacctaattg atagtgtttt
    31741 tgttctttgc tttttaatag ttggttcgtt tctttgattc gatgattgcg aaaggtacga
    31801 ccaatatgtt ggacgatgtg aaaccggtca ataatcagct gtgcttttgg aaacagcttt
    31861 ttaacgagcg atacataagg agcgtacata tcaatcacga tccattcgac cgcttcacga
    31921 atttctcgtg aaaaatgact aaaataacgt tttaaaaaag gcagttgtcg gttctcgaca
    31981 atgtccaata agcgctgtgt ttgtccatcc atcatgatga aactcatagc acctgaaaca
    32041 ccccgaactg atttgaattc atcaaaacaa agtaccttag gtaacggtgt ccgaaaagga
    32101 ttcaacggac gataaaatcg cttcataata cggtaaacag aagagaccga tagatttttc
    32161 tgagcggcga tctctgtcat tgaggtattt tttttcagac gagtcacgac agaccagcgg
    32221 actttctcac tgatgaaaca atgttttttc gcaacagaag tatctgcgac aaaggtccgc
    32281 tgacaagctt tgcatttgaa gcgttgcttt ttcaattcga ggtaggtacg gtattcagaa
    32341 acatcgttca ttaacaaccg gacggttgtt gtaccccaac gcacaatatc tgaagcaatc
    32401 tggtgtttac agtggatgca ttcttgggct gtataaatca agtttccacg ataaatatga
    32461 cagatttgcc ctttgtattt ttcttttgtg agacaatttt cgttaaaagt aactgataag
    32521 tctagaatat ctaatgtttc tttgataagg tgagtgtaag acatcttgat tcctcctttt
    32581 gggttggttc gccaaattaa ttctaaagga tttcaaggtg tcttttctat atgttttgga
    32641 aaataaaaaa gatgctggtg tcatccacca acatcaaaaa gtatagagcc gataataaaa
    32701 gcagcatgat caactatttg tcattgacca tgctgtcttt ttttattcta tacacggttt
    32761 gtctcgtaac attgtagtct ttagcaatct tagcaatcgc aacaccattt ttaagatctt
    32821 caacgatgct tttgtaaaca aggcgacgtt ggggatcttt tgcgtctgca ctgtataatt
    32881 tgggccgccc tttgtagacg ccgtttgctt ttgcgatctt aattccttgt gcctggcgac
    32941 gtttcgattc agtccgttct tgttcagcga tcatggccaa aatttggatg atcagatcct
    33001 taatgaattt atccaggaga ggattgccaa ttgcttcagc catgatcggt aaactagtaa
    33061 tgatcagctt cacatttttc ttcttcaagt aattgactga agtgatgatc tcgtcataat
    33121 ttcttccaag tcgatcaata gcttccacaa taaaaatatc ttgatctcgg acgtaatcta
    33181 atgcttcttg gaaaacaggt cgatgagtaa tcgttgcgcc agattgtttc tcgatgaaaa
    33241 ttctctctgc accgaatttt ttcatttctt caatctggcg ttgttcattt tgatcgatcg
    33301 atgagacacg tatgtatgca actctcaaaa cttttaccta ctttctgcaa ctatttaaaa
    33361 tacaccctaa tcatacacga ggaagccata tttttcaatg ttataccagt gtctatttag
    33421 ggtaaacctt atatagacaa aaactaatga tggaggaaat agtatgagaa ttttttgtaa
    33481 gtgtctactg ataacttatt ctcaaatgtt gtaaggattt tattcatttg ttaatattaa
    33541 agaacggaac tccaaaaaag tccgtactct aatttgcagt ctctcactct tttagagtga
    33601 gagtttttat tagattttca aattaattag taaagtgata gaataaattg atcatacaaa
    33661 tcaaaagaag aagcagggtg atagcatacc tatgcttctt tttttatgta tttagctatt
    33721 tcttctttac aatatcgaac atatgtttgt ataatgtgaa agaatggagt gttatttatg
    33781 atggattatt caaaagagcc agtaaatgat tactttttaa tcgatatgaa aagcttttac
    33841 gcaagtgtcg aatgtataga aagaaattta gatccattaa caacagaact tgttgttatg
    33901 agtcgagctg ataatactgg ttcaggattg atattagctt cttctcctga agcaaaaaag
    33961 cggtatggta ttacaaatgt gagtagacca cgtgacttac cacaaccatt tcctaaaaca
    34021 ctacacgttg ttccaccacg tatgaaccta tatatcaagc gaaatatgca ggtaaataat
    34081 attttcagaa gatatgtggc tgatgaagat ctactgattt actcgatcga tgaatcaatc
    34141 ttaaaagtga cccgatcact gaatcttttt acgactgaag gaacacgaag tcaacggaga
    34201 aagaagctgg ctcaaatgat ccaggagaat attaaagaag agctaggatt gattgctaca
    34261 gtaggtgtcg gagataatcc ccttttggct aaactagcct tagacaacga agcaaagcat
    34321 aatgaaggat ttgttgcgga atggacgtac gaaaacgttc ctgaaaaagt atggaatatt
    34381 cctgaaatga cggacttttg gggaattggc tctcgaatga aaaaaagact caatcagatg
    34441 gggattatga gcattagaga tcttgctaac tggaatcctt atacgattaa gaatagacta
    34501 ggtgtgattg gcttacagct gtacttccat gctaacggaa tcgatcgaac agatatagca
    34561 atcccaccag aaccgacaaa ggaaaaatca tatggaaatt cacaagtgtt accacgagat
    34621 tatactagaa gaaatgaaat cgagctggtg gtaaaagaaa tggcggaaca agtagcgata
    34681 cgcattaggc agcataactg taaaacaggt tgtgtccatt tacacattgg cacgtcgatc
    34741 ttagaaacga gaccagggtt ttcacaccag atgaagatcc ctatcacaga taatacaaag
    34801 gaattgcaga attattgtct tttcttgttt gataagtatt atgaaggaca agaagtaagg
    34861 catgttggaa taacctatag caagcttgtg tacaccgatt cgcttcagct ggatttattt
    34921 agtgatccac aaaagcaaat tgacgaagaa aatttagata aaattattga caagattcgg
    34981 caaaaatatg gttttacgtc gattgtacat gcttcttcaa tgttagaagg cgctagaagc
    35041 attactagaa gcacacttgt tggtggtcat gcgggcggaa atgggggaat taaaaatgat
    35101 tgattacaat gatcgtggac gtttaaagtg ggcagggttt tatttatctg atcatactga
    35161 agaaattgat gccgacaatg aacaacgaac cagtcaaaat ttagcaaaag aacaaatgac
    35221 gactgaagag attgcggaag tattgaacgc tgcagtcata aaaaatagat cagtatctat
    35281 tcaaaaagaa gaacgaaacg ctgaaggata ctatccagaa gatatcattg gcaagatctt
    35341 aggtagtgat gagctgggga tctacgttgg aaaagacaaa attcactacg acgaaatacg
    35401 tcatatcgaa ttttaccagg ataataaatg gagtcgatta gaatgaacat tatccagcaa
    35461 tatgagctaa agtatataac ctttgatcag ctatcagaag agatttgggg ttatggccaa
    35521 cgtttgataa atgaggttgg tgttgagcgc ttctctttct atgtagaagc tgcagcaggt
    35581 tatcataatt ttaggtttta tatcttcccg ttatatatat aaggtatttt acggattcta
    35641 tagagttatc tctatgaatc cttttttgtt tttacaaata ggagtagata ctagaataat
    35701 gcgtgtgtta aactattatt gcaaacgcaa taataaaaga aagtaggctt acgcaccatg
    35761 tctatcaata catttgttta ctcgcacccg atcaatgttt acattatcaa gaatttagga
    35821 atcactgtag aacaattttg tgagttatat gcctacccac aaggaacggt tgcaagctgg
    35881 ataacccgac aacgtagaat aaaatcatta cctgcttcat tcgtttatga tttaagcctg
    35941 gcctctagtt taaacatgtc tgatgtttat gaaaagctcc tgtctttaga aaaagaatat
    36001 gattccttca agattaaaca tgataaaaaa ataaaaaaac atatataata tcaatcacaa
    36061 ttgtataata ttacgatatc ttaatatcat gatatcgtaa tattgttttt ttctaagaaa
    36121 atgcactata agaagggaat tattagtaac aatatagaca gtttagtaat gtttaaatta
    36181 ttctagttgc tgctcgcaaa acatatttct tatcattaat aaaaaatttt aaagtaataa
    36241 aaagtgatta ttttaatttc gaataacata tgaataatct ttatatccga accgatatat
    36301 atctttaaaa caaaataatc acacaatatt acaatataat gcatatacga tattgcaata
    36361 tcacaatatt atgatataat tatattataa tataagatga atgggggata ttttaatggc
    36421 aagaatattg tcagtagcca atcaaaaagg tggagtttct aaaactacga ctagcgttaa
    36481 tttagcagca tgtttgaaat ttgtttacgg taaaaatgta cttttagtgg acattgatcc
    36541 tcagggaaat gctacagata atgtaggttt cgatatagat ggaacaaacc aacctacaat
    36601 ttatgaagta ttaaaagggg aggctgacat tacagatgct attctggact ataaaggaat
    36661 tgatgttttg ccagccgaca tagccctttc ttctgcagag agggaattta ctcaagtagg
    36721 aagtgaacac aggcttaaaa gagtacttca accaatcaag gacaactatg attatattat
    36781 aattgattgt ccaccaagtt taggaatgct tacagtcaac gcatttactg tttctgatga
    36841 aattatcatt ccagttgaag ctgcgtattt ctcattaaaa ggactaataa agttaagtga
    36901 aactattgaa acggtaaaag aatatacgaa cgacaagctt gaagtacgag gagttctatt
    36961 tactaagtat aataagcgtt ataacatttc taaagaaatg acgtctgcag caaccgaaat
    37021 ttctagagtc attggtgcaa aaattttcaa aacttatatt cgtaggacaa taaccgttga
    37081 cgaagcgcaa gctgctggat cagatctaat caattttaat aaaccctcaa cagctgaaga
    37141 tgactataaa gcatttacag aagaatattt aaaagaagtt ggtgattttg atggcagaag
    37201 ataatcgcag tcaagctgca gtaagtagat tactaggaaa taaaaataaa aagaatttta
    37261 aatcaaaaga agtagaagaa atcgaattaa ccaagaaaaa tataagtaaa gtcataaaag
    37321 atcaaggaag tagtgtaaga acagcagata gcattcgtat aaatccaatt ctaatgtcag
    37381 cactcaaata ttggacgact attgctgaat cagacaaaag taaaccagac gttatagaag
    37441 atgcgctatt aaagtccata cctgaagaat acttgattga aggatataaa ctagcaaaga
    37501 aacaaaataa aatttaattt acattcaata tcacgatatc ataatatcgt gatatttttt
    37561 ttataaaaat cagtagtatc aaagctgata agtcgcttat cttcatattg taatattacg
    37621 atatcgtgat ataatattat tgtaatatcg tgatatagtt actatgagct taaaccttga
    37681 aatagagcgg tttgctttaa tttatttttt aaggtaaact aaaaaaagat aaaaaaagac
    37741 tactgcttta acaaagtttg gcgacttatc agcagtagaa aaatatatag tggatagata
    37801 tatttgttta attcattgta acatagtttt gaacaaaacg ctatcctaca gaaagaggat
    37861 tggct
//
