LOCUS       NZ_CP010355             7579 bp    DNA     circular CON 25-DEC-2023
DEFINITION  Acinetobacter johnsonii XBB1 plasmid pXBB1-4, complete sequence.
ACCESSION   NZ_CP010355
VERSION     NZ_CP010355.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN03268929
            Assembly: GCF_001484935.1
KEYWORDS    RefSeq.
SOURCE      Acinetobacter johnsonii XBB1
  ORGANISM  Acinetobacter johnsonii XBB1
            Bacteria; Pseudomonadota; Gammaproteobacteria; Moraxellales;
            Moraxellaceae; Acinetobacter.
REFERENCE   1  (bases 1 to 7579)
  AUTHORS   Zong,Z.
  TITLE     The complete genome of Acinetobacter johnsonnii strain XBB1 carrying
            blaNDM-1 and blaOXA-58 from hospital sewage
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7579)
  AUTHORS   Zong,Z.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-DEC-2014) Center of Infectious Diseases, West China
            Hospital, Sichuan University, Guoxuexiang 37, Chengdu, Sichuan
            610041, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.6; Sspace v. 2.0
            Genome Coverage                   :: 100x
            Sequencing Technology             :: Illumina; 454
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 12/25/2023 04:54:53
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,995
            CDSs (total)                      :: 3,887
            Genes (coding)                    :: 3,684
            CDSs (with protein)               :: 3,684
            Genes (RNA)                       :: 108
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 83
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 203
            CDSs (without protein)            :: 203
            Pseudo Genes (ambiguous residues) :: 0 of 203
            Pseudo Genes (frameshifted)       :: 103 of 203
            Pseudo Genes (incomplete)         :: 102 of 203
            Pseudo Genes (internal stop)      :: 46 of 203
            Pseudo Genes (multiple problems)  :: 41 of 203
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP010355.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..7579
                     /organism="Acinetobacter johnsonii XBB1"
                     /mol_type="genomic DNA"
                     /strain="XBB1"
                     /db_xref="taxon:1242245"
                     /plasmid="pXBB1-4"
     gene            166..1272
                     /locus_tag="EHS42_RS19430"
                     /old_locus_tag="RZ95_19280"
                     /old_locus_tag="RZ95_RS19230"
     CDS             166..1272
                     /locus_tag="EHS42_RS19430"
                     /old_locus_tag="RZ95_19280"
                     /old_locus_tag="RZ95_RS19230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004889328.1"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase"
                     /protein_id="WP_004889328.1"
                     /translation="MSSNFQEELNMAFDSLKKNIEKPNILLVGGTGVGKSSLLNLCFGE
                     DIAATGVGKPITQHINKFTSPNIPIVLFDSKGYEIGSEQESLFQKEVIELCSETQNSIE
                     DKPHLVWYCIQTIGSRITDFDINIIRKIELSDIPISIVLTKADLVSDDDASLLKTAILN
                     EFPKIQIFETTIKENLHGMELEKLISWSTSQLPNALKTAFVSAQKNSLKEKREHAKNAI
                     IQHTTLAFATGFAPIPASSAPLLLANQSKLLARILYIYNLDRAVDSVSAIIQTAIASSL
                     PIAGKYLVSQILKFFPGVGTAVGGTINGSVAASITSAFGFAVSEACAKLTELGLDHFDD
                     SSFMKNFDDNLMKIFMEYLKQAKGNKND"
                     /name="GTPase"
     gene            1265..1966
                     /locus_tag="EHS42_RS19435"
                     /old_locus_tag="RZ95_19285"
                     /old_locus_tag="RZ95_RS19235"
     CDS             1265..1966
                     /locus_tag="EHS42_RS19435"
                     /old_locus_tag="RZ95_19285"
                     /old_locus_tag="RZ95_RS19235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005105744.1"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA];
                     GO:0003924 - GTPase activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase domain-containing protein"
                     /protein_id="WP_005105744.1"
                     /translation="MTNTNYNIAIIGQTGVGKSSLINYLFGSEVAKSGIGRPVTTNGFH
                     EINHKIKDMSVKIYDSWGLEVGKEEQWLKELNTELKKRGIDKPASDWFHSIFYCIAASG
                     GRIQDADSKIVKKLIDENYKVSIVLTKADSLTEEEEAEFIQVIAHELGNNIAIIPVCSE
                     HKKTRGGEIIPFGKEIVEKQSLIDLVDSLVLRIPFYCKQDIFIFYIQWLIFLLIGNTMK
                     NTMLRKGLTIF"
                     /name="GTPase domain-containing protein"
     gene            2154..2969
                     /gene="sul2"
                     /locus_tag="EHS42_RS19445"
                     /old_locus_tag="RZ95_19290"
                     /old_locus_tag="RZ95_RS19240"
     ARG             2155..2966
                     /name="sul2"
                     /gene="sul2"
                     /gene_name="sulfonamide-resistant dihydropteroate synthase
                     Sul2"
                     /tool="amrfinderplus"
                     /drug_class="SULFONAMIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            3056..>3265
                     /gene="glmM"
                     /locus_tag="EHS42_RS19450"
                     /old_locus_tag="RZ95_19295"
                     /old_locus_tag="RZ95_RS19245"
                     /pseudo=""
     CDS             3056..>3265
                     /gene="glmM"
                     /locus_tag="EHS42_RS19450"
                     /old_locus_tag="RZ95_19295"
                     /old_locus_tag="RZ95_RS19245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008891390.1"
                     /note="catalyzes the conversion of glucosamine-6-phosphate
                     to glucosamine-1-phosphate; incomplete; partial in the
                     middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /name="glmM"
     gene            complement(3423..3635)
                     /locus_tag="EHS42_RS19455"
                     /old_locus_tag="RZ95_RS20560"
     CDS             complement(3423..3635)
                     /locus_tag="EHS42_RS19455"
                     /old_locus_tag="RZ95_RS20560"
                     /inference="COORDINATES: protein motif:HMM:NF024949.3"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_080632801.1"
                     /translation="MNLPQLFGKNVRLRRNELGLSQERLAELCQFHRTYIGLVERGGRN
                     ISLNHAYRLAKALDTEVSKLTGEIP"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(4166..4369)
                     /locus_tag="EHS42_RS19460"
                     /old_locus_tag="RZ95_19300"
                     /old_locus_tag="RZ95_RS19250"
     CDS             complement(4166..4369)
                     /locus_tag="EHS42_RS19460"
                     /old_locus_tag="RZ95_19300"
                     /old_locus_tag="RZ95_RS19250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005105747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_005105747.1"
                     /translation="MNEAEKERLKEIFRSSKGIVDHEFSQEVIDACKPYEDARHQRILN
                     GETTLEQEEAALMAEWRRLNPK"
                     /name="hypothetical protein"
     gene            complement(4396..4728)
                     /locus_tag="EHS42_RS19465"
                     /old_locus_tag="RZ95_19305"
                     /old_locus_tag="RZ95_RS19255"
     CDS             complement(4396..4728)
                     /locus_tag="EHS42_RS19465"
                     /old_locus_tag="RZ95_19305"
                     /old_locus_tag="RZ95_RS19255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004759129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family toxin"
                     /protein_id="WP_005105749.1"
                     /translation="MTSKKTAKDKRAVLPRSSDYTKEFLADWQRLSRSGRYDMRKLKQV
                     MMLIIANDEPLGAEWVDHALSGNQWKNCRELHVGGDFLLIYRIEPISKFEMVVFVRTGT
                     HSELFK"
                     /name="type II toxin-antitoxin system YafQ family toxin"
     gene            complement(4706..4981)
                     /locus_tag="EHS42_RS19470"
                     /old_locus_tag="RZ95_19310"
                     /old_locus_tag="RZ95_RS19260"
     CDS             complement(4706..4981)
                     /locus_tag="EHS42_RS19470"
                     /old_locus_tag="RZ95_19310"
                     /old_locus_tag="RZ95_RS19260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010113474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="WP_004676369.1"
                     /translation="MTSQTSMLHVRIDDETKLQAQQALKSMGMSVSDAVRIFLTRVVAE
                     QAIPFDVRVPNTTTVAAMNEADALIQAKKARFETVEDLFNDLEKNS"
                     /name="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
     gene            5753..6703
                     /gene="repM"
                     /locus_tag="EHS42_RS19480"
                     /old_locus_tag="RZ95_19315"
                     /old_locus_tag="RZ95_RS19265"
     CDS             5753..6703
                     /gene="repM"
                     /locus_tag="EHS42_RS19480"
                     /old_locus_tag="RZ95_19315"
                     /old_locus_tag="RZ95_RS19265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004786597.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein RepM"
                     /protein_id="WP_001205341.1"
                     /translation="MRDLVVKDNALINASYNLDLVEQRLILLAIVEARESGKGINANDP
                     LEVHADSYINQFGVHRNTAYQALKDACKDLFARQFSYQEKKANGNIRNVMSRWVSQIAY
                     NDNEATVDLIFAPAVVPFITRLEEQFTKYELQQVSSLSSAYAIRLYELLIQWRSTGKTP
                     TIELQEFRKKLGVLDNEYLRMAHLKERVLELSIKQINEHTDITVKYEQHKRGRSISGFS
                     FTFKQKKKDSPSIERDPNTLDLFSKMTDAQRHMFANKLSELPEMGRYSQGTESYPQFAV
                     RIAEMLQDSEKIKELAPYLKKVGYMPSNKKDTVNG"
                     /name="repM"
     gene            6696..7271
                     /locus_tag="EHS42_RS19485"
                     /old_locus_tag="RZ95_19320"
                     /old_locus_tag="RZ95_RS19270"
     CDS             6696..7271
                     /locus_tag="EHS42_RS19485"
                     /old_locus_tag="RZ95_19320"
                     /old_locus_tag="RZ95_RS19270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005102333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid replication DNA-binding protein"
                     /protein_id="WP_001096611.1"
                     /translation="MAKLSLSEVSKKFHIDRSTIYRAVRNGRLSRSSDGQFDLSEVIRC
                     FGEPEQISQQIEPSKSDNDESTKKLIIHLENEVKKYQEREERLMQQIDRMQTLIELKTV
                     APATAAPQQDATACDTDMPQHATTQQDNDYKKNNELNIVENVAVPQQETTAYHSQTLQH
                     ATLQNVAVPQPKKRGLFGRVLNAVFNEE"
                     /name="plasmid replication DNA-binding protein"
     gene            7293..7436
                     /locus_tag="EHS42_RS20320"
     CDS             7293..7436
                     /locus_tag="EHS42_RS20320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004786602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_005105742.1"
                     /translation="MKKLKEILQGIAFLFVGIPIMIMASIIDQRAFKKELDERQKEKDQ
                     AS"
                     /name="hypothetical protein"
     Typing          5754..6703
                     /name="rep_cluster_1172"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="96.951"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 gcatttcgta taaggtgtat tatgttaatt ttagaaaatc taattaataa acaaaatatt
       61 gcataggtca aatttagctg aaattattaa tatccatata ttttcaaaga aataaaaagg
      121 tagaatattc aatattctta aataattaca aactatgggg actatatgtc tagtaatttt
      181 caagaagagt taaatatggc atttgactca ctgaagaaaa atatagaaaa accaaatatt
      241 cttttagttg gtggtactgg agtcggtaaa agttctttac taaatttatg ctttggtgaa
      301 gatatagcag ctactggagt cggtaaacct ataacacagc atataaataa atttacgtca
      361 ccaaatattc caattgttct ctttgatagt aaagggtatg aaattggttc tgagcaagaa
      421 tcacttttcc aaaaagaagt tattgaactt tgtagtgaaa cacaaaactc aattgaagat
      481 aagcctcatt tagtatggta ctgcatacaa acaataggtt ctcgaattac agattttgat
      541 attaatatca ttcggaaaat agaactttca gatataccta tttcaatagt tttaactaaa
      601 gcagatttag ttagtgacga tgatgcaagc ttgttaaaaa cagcaatttt aaatgagttt
      661 ccaaagattc aaatctttga aacaacaatt aaagaaaatt tacatggaat ggaattggaa
      721 aaacttattt catggagtac tagtcaatta ccaaatgctt taaaaactgc ttttgtttct
      781 gctcaaaaaa atagccttaa agaaaaaaga gaacatgcaa aaaatgccat tattcagcat
      841 acaacattag cttttgcaac tggatttgct ccaataccag catccagtgc accactttta
      901 ttagctaatc aatcaaagtt attggcaaga atactatata tatataattt agatcgcgct
      961 gttgatagcg tatcagcaat tattcaaaca gcaatagctt cgtctttacc aatagctgga
     1021 aaatatttgg ttagtcaaat tctaaagttt ttcccaggtg tcggaacagc tgtaggtgga
     1081 acaattaatg gttccgtagc ggcatctatt acttctgctt ttggctttgc agtttcagag
     1141 gcatgtgcaa aattaaccga gttagggtta gatcattttg atgatagctc cttcatgaaa
     1201 aattttgatg ataatttaat gaaaattttt atggagtatt tgaaacaagc gaagggaaat
     1261 aaaaatgact aatacaaact ataatattgc aattattgga caaacaggtg ttggtaaaag
     1321 tagcttaatc aattacttat ttggttcaga agtagcaaaa tcaggaattg gtcgaccagt
     1381 tacaacaaat ggttttcatg aaattaatca taaaataaaa gatatgtctg taaaaatcta
     1441 tgattcttgg ggactagaag ttggcaaaga agaacagtgg ctgaaagagc ttaatactga
     1501 gttaaaaaaa agaggaatag ataaacctgc atcggattgg tttcactcta ttttttattg
     1561 tattgctgct tctggagggc gtatacagga tgctgactct aaaattgtaa aaaaacttat
     1621 agatgaaaat tataaagtta gtatcgtatt aacaaaagca gactctctaa cagaagagga
     1681 agaagctgaa tttattcaag tgattgctca tgaacttgga aataacattg ccattatccc
     1741 tgtatgtagt gagcacaaaa aaacacgtgg tggagagata attccatttg gtaaagaaat
     1801 agttgaaaaa caatcgttga ttgatcttgt agattctcta gtcttacgta tcccattcta
     1861 ttgtaaacaa gacattttta tcttttatat tcaatggctt attttcctgc taattggtaa
     1921 taccatgaaa aataccatgc tcagaaaagg cttaacaata ttttgaaaaa ttgcctactg
     1981 agcgctgccg cacagctcca taggccgctt tcctggcttt gcttccagat gtatgctctt
     2041 ctgctcctgc agctaatgga tcaccgcaaa caggttactc gcctggggat tccctttcga
     2101 cccgagcatc cgtatgagac tcatgctcga ttattattat tatagaagcc cccatgaata
     2161 aatcgctcat cattttcggc atcgtcaaca taacctcgga cagtttctcc gatggaggcc
     2221 ggtatctggc gccagacgca gccattgcgc aggcgcgtaa gctgatggcc gagggggcag
     2281 atgtgatcga cctcggtccg gcatccagca atcccgacgc cgcgcctgtt tcgtccgaca
     2341 cagaaatcgc gcgtatcgcg ccggtgctgg acgcgctcaa ggcagatggc attcccgtct
     2401 cgctcgacag ttatcaaccc gcgacgcaag cctatgcctt gtcgcgtggt gtggcctatc
     2461 tcaatgatat tcgcggtttt ccagacgctg cgttctatcc gcaattggcg aaatcatctg
     2521 ccaaactcgt cgttatgcat tcggtgcaag acgggcaggc agatcggcgc gaggcacccg
     2581 ctggcgacat catggatcac attgcggcgt tctttgacgc gcgcatcgcg gcgctgacgg
     2641 gtgccggtat caaacgcaac cgccttgtcc ttgatcccgg catggggttt tttctggggg
     2701 ctgctcccga aacctcgctc tcggtgctgg cgcggttcga tgaattgcgg ctgcgcttcg
     2761 atttgccggt gcttctgtct gtttcgcgca aatcctttct gcgcgcgctc acaggccgtg
     2821 gtccggggga tgtcggggcc gcgacactcg ctgcagagct tgccgccgcc gcaggtggag
     2881 ctgacttcat ccgcacacac gagccgcgcc ccttgcgcga cgggctggcg gtattggcgg
     2941 cgctgaaaga aaccgcaaga attcgttaac tgcacattcg ggatatttct ctatattcgc
     3001 ggttcagcag gcatgtcccc tttgagggcg acccgacgac aggataatcg accttatggt
     3061 gcgcaaatat ttcggcacag acggtattcg tggcaaagcc aacgaaggcg cgatgacggc
     3121 ggaaaccgcc ttgcgcgtcg gcatggcggc tggccgtgtc tttcgtcgcg gtgaccaccg
     3181 ccatcgtgtc gtgatcggca aggatacgcg cctgtcgggc tatatgcttg aacccgcgct
     3241 cacagccggt ttcacctcga tgggcaatta ctagcagttc cttagccatt gtactaactg
     3301 aaaagtttgg agctttgtta gttcctagtt tagatccacc gaatgagtca cttactgtag
     3361 ctttttcatg attggttaat aaatcatata aatcttgttc aaaagtcatt ttttttccta
     3421 agttaaggga tctccccagt taacttagaa acttcagtgt ccaaagcttt tgctagtcta
     3481 taagcatgat tcaatgaaat atttctccct cctctttcaa ctaagccaat gtatgttcta
     3541 tgaaattgac acaactcggc taagcgttcc tgagaaagcc ctaattcatt tcgtcgaaga
     3601 cgaacatttt ttccaaataa ctgaggtaaa ttcatacttc aattatggtt tttgatgact
     3661 attaatcgac agactaatga tagcaaatga aatgtaatta gctaaaaaat ataaatttaa
     3721 tgatagttcc ttatttaaca taaaatctct tatacgagac tccaggtctg gtggcttact
     3781 ctcaagcgag aaagattttt tctaaatcta aaactactcg atcaatgatc aattaaagcc
     3841 tgatagttat ttttgtcggc caaaataaac tccgaaggac aagatgagac attgagcgta
     3901 tgcgaattgt gtaggtattg gggtagtaca gcttgcatgt actagtacaa tacacatctt
     3961 gcctcaccgt acaaattcca gtttgcgtat atttgccttt atttgataca taccacacac
     4021 taggatttgc gtttttttga tcttatttgc tgatttttgc ttttatttgc gtttttttga
     4081 taaaactgtt tgctttaatt tgatgaaatt tgctcttttt tgataaaaaa acaccaaaat
     4141 aaatgcaatt taagctctta taagcttatt tagggttcaa tcgtctccat tcagccatta
     4201 aagctgcttc ttcctgctcc aaagtcgttt caccattcaa aatacgttgg tgtcttgcat
     4261 cttcataagg tttgcaagca tcaatgactt cttgagaaaa ttcgtgatct acgattccct
     4321 ttgagcttct aaaaatctct tttaaccgct ctttttctgc ttcattcata aatacagatc
     4381 ctctttgttt ggtgcttact taaataactc gctatgcgtt ccagtacgca caaaaaccac
     4441 catctcgaac ttagagattg gttcaatacg atagatcagc agaaaatcac caccgacatg
     4501 cagttcacgg cagtttttcc attgattacc actgagtgca tgatcaaccc attcagcacc
     4561 taaaggctca tcattagcaa taatcagcat catgacctgt ttaagctttc tcatgtcata
     4621 acgaccacta cgagaaagcc tttgccagtc tgctaaaaac tctttggtat aatccgatga
     4681 tcgaggtaaa acggcccgtt tatctttagc tgtttttttc gaggtcatta aacaagtctt
     4741 ctacagtttc aaaacgggct ttcttggctt gaatgagcgc atcagcttca ttcatagcag
     4801 ctacagttgt ggtattgggt acacgtacat caaatggaat cgcctgttcc gctactacac
     4861 gagtcagaaa gattcgtaca gcatcagaca cagacatacc cattgatttc aaagcttgtt
     4921 gcgcctgtag ctttgtttca tcatcaattc gaacgtgtag cattgaggtt tgagaagtca
     4981 tatcttcacc tgaatgttat gtaactcaat tgagatacat agtagcatat tcaggcctga
     5041 atatttcaaa taaaaggata tttcgattta ttgatcaaac agaaaaatta ggccaataaa
     5101 aaaatatcgc atttaaacgc tctattttca ccatagagag gcgatctcaa acttaaacat
     5161 ataatctacc taaaaacaaa aaagtctctc taagctcaaa tagaagcaaa tgacacaaca
     5221 ctaataaacc actagaaaac attaaccaag cgagtgtcta cgagcgacat caccaaaatt
     5281 cgcacctcga ctttctgaaa aacagctttt taggctgtga agcctaaata agcgttaatc
     5341 acatgtagaa atttgagtct agatcgagcg tagcgagtaa aaaagcttta tgagcgaagc
     5401 gaattcatcg tgcttttgct ttttattgaa gtcacaacga gatgagccaa aaaattgccc
     5461 cgacgaatcg agcgaaagcg agattcaata gagtttgagc gtagcgaaaa ccaagggcaa
     5521 tttttctttg cctgggcttt taattatttt aaatttttta aatgctttta gatggcttga
     5581 aagccttatg aataaagggc tttatctctt atatgtccac gtttaccttg caatatgtcc
     5641 acgtttacct tgcaatatgt ccacgtttac cttgcaatat gtccacgttt accttgcatt
     5701 agtacacaaa taatattaac gtgtatttat acacaataaa aaaatagtgg ctatgagaga
     5761 tttagttgta aaagacaatg ccttaatcaa cgcaagctat aacttagact tagtagaaca
     5821 acgtttaatt ttattggcta ttgttgaagc aagggaaagt gggaaaggga ttaatgcaaa
     5881 tgatccatta gaagttcatg cagatagtta tatcaatcaa tttggtgtac accgtaatac
     5941 agcttatcaa gccttaaaag atgcttgtaa ggatttattc gcgcgtcaat ttagctatca
     6001 agagaaaaaa gctaatggga atatccgaaa tgttatgagt cgttgggtat ctcaaattgc
     6061 ttataacgac aatgaagcaa ctgtagactt aatatttgca cctgctgttg ttccctttat
     6121 aaccagactg gaagaacaat ttactaaata tgaattacag caagttagta gtcttagtag
     6181 cgcttatgcc attcgcttat atgagcttct aattcagtgg cgaagcactg gtaaaacccc
     6241 aactatagaa ctacaagaat ttagaaaaaa gttaggcgtt cttgataatg aatatttacg
     6301 gatggctcat ttaaaagagc gtgttttaga gctttcaatt aaacaaataa atgagcatac
     6361 ggatataact gtaaaatatg aacagcataa aagaggacgt tctatttcag gattttcttt
     6421 tacctttaaa cagaaaaaga aggatagccc atcaatagaa agagatccga ataccttaga
     6481 ccttttttca aagatgaccg atgctcaacg gcatatgttt gcaaacaaac tttcagaact
     6541 cccagaaatg ggtcgctatt cacaaggaac tgaaagctat cctcaatttg ctgttcgtat
     6601 tgctgagatg ctacaagact ctgaaaaaat caaagaacta gccccatacc taaaaaaagt
     6661 gggatacatg ccatcaaata aaaaggacac agtaaatggc taagttatcg ctaagtgaag
     6721 tatctaaaaa atttcatatt gataggtcaa ccatttatag agctgtacgt aatgggcgtt
     6781 tatcacgctc tagtgatggt caatttgacc tttcggaagt gattagatgc tttggggagc
     6841 ctgagcaaat atctcaacaa attgaaccat ctaaatcaga taatgatgaa tctacaaaaa
     6901 aactcattat tcatttagaa aatgaagtca aaaaatacca agaacgtgaa gagcgtttaa
     6961 tgcagcaaat cgaccgtatg cagacgctta ttgagttaaa aactgttgcg cccgccacgg
     7021 cagcgccaca acaagatgct acggcatgcg acaccgatat gccacagcat gcgacaacac
     7081 aacaagacaa tgattataaa aagaataatg aattaaatat tgtagaaaat gtagctgtgc
     7141 cacagcaaga aactacagca taccacagcc aaacgctaca gcatgccaca ttacaaaatg
     7201 tggcagtgcc acaacctaaa aaacgaggct tatttggccg agtactgaat gcggtattca
     7261 atgaagagta agctctccaa ggagcattgt ttatgaaaaa actgaaagag atcctgcaag
     7321 gtattgcctt tttatttgtt gggattccga tcatgatcat ggccagcatc atagatcaac
     7381 gtgccttcaa aaaagagctg gatgaacgcc aaaaagaaaa agaccaggca tcctgattat
     7441 tcaattgagc taatcaaaac cgtggaacat tgattaaaga ttaagcgtgg aacggtagta
     7501 ttcaacaaaa aagccgaact cagctaagtt cggcttttta gtatcagtta aagcattgaa
     7561 ttatatgaaa taaagtaaa
//
