LOCUS       NZ_CP010097            12866 bp    DNA     circular CON 10-APR-2024
DEFINITION  Bacillus thuringiensis serovar galleriae strain 4G5 plasmid pBMB12,
            complete sequence.
ACCESSION   NZ_CP010097
VERSION     NZ_CP010097.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN03074947
            Assembly: GCF_000803665.1
KEYWORDS    RefSeq.
SOURCE      Bacillus thuringiensis serovar galleriae
  ORGANISM  Bacillus thuringiensis serovar galleriae
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
            Bacillus cereus group.
REFERENCE   1  (bases 1 to 12866)
  AUTHORS   Zhu,L., Zheng,J. and Sun,M.
  TITLE     Complete genome sequence of Bacillus thuringiensis serovar.
            galleriae strain HD-29
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 12866)
  AUTHORS   Zhu,L., Zheng,J. and Sun,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-DEC-2014) College of Life Science and Technology,
            State Key Laboratory of Agricultural Microbiology, Huazhong
            Agricultural University, Shizishan Street No.1, Wuhan, Hubei 430070,
            China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Velvet v. 2.3
            Genome Coverage                   :: 389x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000803665.1-RS_2024_04_10
            Annotation Date                   :: 04/10/2024 17:44:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,928
            CDSs (total)                      :: 6,766
            Genes (coding)                    :: 6,440
            CDSs (with protein)               :: 6,440
            Genes (RNA)                       :: 162
            rRNAs                             :: 14, 14, 14 (5S, 16S, 23S)
            complete rRNAs                    :: 14, 14, 14 (5S, 16S, 23S)
            tRNAs                             :: 115
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 326
            CDSs (without protein)            :: 326
            Pseudo Genes (ambiguous residues) :: 0 of 326
            Pseudo Genes (frameshifted)       :: 122 of 326
            Pseudo Genes (incomplete)         :: 213 of 326
            Pseudo Genes (internal stop)      :: 89 of 326
            Pseudo Genes (multiple problems)  :: 77 of 326
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP010097.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..12866
                     /organism="Bacillus thuringiensis serovar galleriae"
                     /mol_type="genomic DNA"
                     /strain="4G5"
                     /serovar="galleriae"
                     /host="Dendrolimus sibiricus"
                     /db_xref="taxon:29338"
                     /plasmid="pBMB12"
                     /geo_loc_name="Czechoslovakia"
                     /collection_date="1970"
     gene            join(11697..12866,1..213)
                     /locus_tag="BT4G5_RS34335"
                     /old_locus_tag="BT4G5_34340"
     CDS             join(11697..12866,1..213)
                     /locus_tag="BT4G5_RS34335"
                     /old_locus_tag="BT4G5_34340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000708825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_042991731.1"
                     /translation="MKKAAIIFLCTFCIIFRTVPVFADTPSFQMVGSKGVSIENKGLVG
                     GYYSLSLKISDAKDVVTFQLSELMLVNDCSFNFGLVKWTRPSQEKNEFDIKVKENGTYA
                     FYVFVNGKVKGYVRFKIKGFPKNAEGAGVTQYWGQGAKYYELPEEHVNPEDFRDKDGEN
                     NGICVNEKISDDKPGGSGDIEEPKEDNKPPVEGGGGSDKAIKEALDKITSAVNEISKNT
                     GETAKNTGEIKKNTDEIAKNTKEIADAVKDIRDNLKIPDDMDLSIKPVLPEDIKPDKPK
                     QPDKPFEDKQEHFKEGEQEKPPDKLPVAPGPAECWGDVCKDKDNQKEEDMKKDKDMDKE
                     EPMKPDKPMEKEDMKPEKPMTPDKPMEKEDMKPDKPMTPDKPMEKEDMKPDKPMTPDKP
                     MEKEDMKPDKPMTPDKPMDREGEMKKDNDMKQDKPMTPWEEMKPSDEGSELCWHVVNGK
                     CG"
                     /name="hypothetical protein"
     gene            183..1379
                     /locus_tag="BT4G5_RS34340"
                     /old_locus_tag="BT4G5_34345"
     CDS             183..1379
                     /locus_tag="BT4G5_RS34340"
                     /old_locus_tag="BT4G5_34345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016090439.1"
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin type III domain-containing protein"
                     /protein_id="WP_155278152.1"
                     /translation="MACSKWKMRIKKFLLVVPLLLGILFIGDTSAFAEVSRASLGNDLL
                     KGVSGSMCGSTVTKITDGNPSTGETLFKTCREIRFKLPKVSNVSGFLYIKTNKWTSDKL
                     AIDFKKVDGQVKTITYNQASVNSNNYIQVFVKDVSEVVLRNFDDTGAIEIMSFELYEGN
                     GDEFFYEDIKELQPTITYDSVTFSYKNPKIDFGYLRIYRDGKLIVDNFKLEQFKDKELS
                     PNTEYKYKFVAVSSDGIESKGIEKVIKTDEKPNLAKPIKPSNPTITPKDGSLIVNLTNY
                     DAGVKVKGYHIVVDGKQVNDSLVTARSYAITGLKNGQSYQVQIKAVSAWNIESDLSNSV
                     PGIPQVQVIPDIAFNFGLSDLMESIKNWFGGIWPIVAFSIAIPLTFIVAFNTKKLFLR"
                     /name="fibronectin type III domain-containing protein"
     gene            1541..1966
                     /locus_tag="BT4G5_RS34345"
                     /old_locus_tag="BT4G5_34350"
     CDS             1541..1966
                     /locus_tag="BT4G5_RS34345"
                     /old_locus_tag="BT4G5_34350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000970219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_015484803.1"
                     /translation="MMEKFVKFLKGGFEAVIKSLKTFIDFLATPFQYLLDFLKGIFYFI
                     EKLFQVVVAIIKLFVALFQFLGAVIAGFFKTLFLWVQPNFDGGNVSFPSASMKGFKTAT
                     DILLPTGLLTVVPMVVTCFIWYLFVKKLMDLFRGGHH"
                     /name="hypothetical protein"
     gene            1966..2226
                     /locus_tag="BT4G5_RS34350"
                     /old_locus_tag="BT4G5_34355"
     CDS             1966..2226
                     /locus_tag="BT4G5_RS34350"
                     /old_locus_tag="BT4G5_34355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000992627.1"
                     /translation="MNALIDTIFNPVLGWLAQMAKYLNDLSVPASRPLRISDYLGVFAY
                     LYGWTTVITTLFALVFVYFVCYIIMTYSSLFIRFKDTVKWW"
                     /name="hypothetical protein"
     gene            2533..2895
                     /locus_tag="BT4G5_RS34355"
                     /old_locus_tag="BT4G5_34360"
     CDS             2533..2895
                     /locus_tag="BT4G5_RS34355"
                     /old_locus_tag="BT4G5_34360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000880239.1"
                     /translation="MLAKTKRKVQPQFEGHRALIIKEEGTCTVEQVISFDSEILETSTA
                     MLPRDNELRLLDDNHGYVYHIYNLEKPARIEAENIKRLRRSSALKGIFEFETGKKQFDL
                     IGFMPWVIIVLLAIFK"
                     /name="hypothetical protein"
     gene            2909..3316
                     /locus_tag="BT4G5_RS34360"
                     /old_locus_tag="BT4G5_34365"
     CDS             2909..3316
                     /locus_tag="BT4G5_RS34360"
                     /old_locus_tag="BT4G5_34365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000504993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_015484804.1"
                     /translation="MSEVTLEKTVVEEVLPDVQDIMKEEILEEDTSSESIETVQLFQYM
                     KENSVPLNASQMKGILLLNENGCKDIADYVISVKKQSLPLAFYEKVLKILTMFDRIKGN
                     AKLSHLLKANANPSLSLSANSAKVVKGNELA"
                     /name="hypothetical protein"
     gene            3313..3915
                     /locus_tag="BT4G5_RS34365"
                     /old_locus_tag="BT4G5_34370"
     CDS             3313..3915
                     /locus_tag="BT4G5_RS34365"
                     /old_locus_tag="BT4G5_34370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_015484805.1"
                     /translation="MNVMVFEGPLGSGKTLGMTLFAHHFKQKSNCVLYSNYGVVGSKPF
                     TEIEHFKNIAQEKSTILNLDEAHIDLDARSFSSNSVKFFSQVSYYLRKLRCTLFIASPS
                     FDDLDSRIRGITNVLVKVSSDKKYFYYTMYDIQSKRYLKRMRISKKKAFVVGSKIYDTS
                     AMVSPVKVPEKRQDFMEFLEALKTTAEEYGRQYKHSA"
                     /name="hypothetical protein"
     gene            3986..4177
                     /locus_tag="BT4G5_RS34370"
                     /old_locus_tag="BT4G5_34375"
     CDS             3986..4177
                     /locus_tag="BT4G5_RS34370"
                     /old_locus_tag="BT4G5_34375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000511844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_015484796.1"
                     /translation="MGILKKKRFREEVKRINKAHEEMKRFLDVLMDRYGLDEEEINNCE
                     VIKHHFDNLDLMFSQMAK"
                     /name="hypothetical protein"
     gene            4809..5015
                     /locus_tag="BT4G5_RS34375"
                     /old_locus_tag="BT4G5_34380"
     CDS             4809..5015
                     /locus_tag="BT4G5_RS34375"
                     /old_locus_tag="BT4G5_34380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000365465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_015484797.1"
                     /translation="MDLPICNEKEVTVLSKTLKYLRSDQSNQVKVHKEYLEDRGWIFDD
                     LSYIDSHIYVVYKKEVVKRNKAF"
                     /name="hypothetical protein"
     gene            5027..5446
                     /locus_tag="BT4G5_RS34380"
                     /old_locus_tag="BT4G5_34385"
     CDS             5027..5446
                     /locus_tag="BT4G5_RS34380"
                     /old_locus_tag="BT4G5_34385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_015484798.1"
                     /translation="MFKKFYREYIHVLFNIVAMFFYFSWCLVGTEFNLLTLIAIGIAIF
                     IFVKYVSMDRKFVNENIDKLKDKKMIFRKYAISGENIGYAVFTNFLLFLLYLGISVYFK
                     DLSVISLLFAFILNVSLLMLTLRVMSKFSLKNSKV"
                     /name="hypothetical protein"
     gene            5458..5793
                     /locus_tag="BT4G5_RS34385"
                     /old_locus_tag="BT4G5_34390"
     CDS             5458..5793
                     /locus_tag="BT4G5_RS34385"
                     /old_locus_tag="BT4G5_34390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_015484799.1"
                     /translation="MFARYRSQDDEFMSQLQFLALGAIMTFLIKFGCISPEVNMLTLFV
                     LFVILIGIYYLFVLLLTKYFYRFLSKQHDKLHAYLCNKYGEKIANRVGLSFLIILIVGM
                     LIVCLLI"
                     /name="hypothetical protein"
     gene            6112..6327
                     /locus_tag="BT4G5_RS34395"
                     /old_locus_tag="BT4G5_34400"
     CDS             6112..6327
                     /locus_tag="BT4G5_RS34395"
                     /old_locus_tag="BT4G5_34400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001169628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_021729341.1"
                     /translation="MTVVKEERKNRVFRFTDTEVSLIDELIDIENDKRMTIAREKNLKY
                     KALNRTSFILYMAEERRRKYEEQGEF"
                     /name="hypothetical protein"
     gene            6406..6627
                     /locus_tag="BT4G5_RS34400"
                     /old_locus_tag="BT4G5_34405"
     CDS             6406..6627
                     /locus_tag="BT4G5_RS34400"
                     /old_locus_tag="BT4G5_34405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_021729342.1"
                     /translation="MEELLHKIIDKLDKIDKDIQEIKTDLKAHRIETDDNFTKLYHLVE
                     EKDVEIDVLNKRLFKNEATVERIKREKH"
                     /name="hypothetical protein"
     gene            6641..6919
                     /locus_tag="BT4G5_RS34405"
                     /old_locus_tag="BT4G5_34410"
     CDS             6641..6919
                     /locus_tag="BT4G5_RS34405"
                     /old_locus_tag="BT4G5_34410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_021729343.1"
                     /translation="MAYSYCVDCESVYSCEDEKCCCGSKKRSVDWEEFAFIMGYPLYPV
                     KKKYGVFHLDLSKRLDADALCDLKADNPELFYYEFKGWKERELKKRN"
                     /name="hypothetical protein"
     gene            6946..8178
                     /locus_tag="BT4G5_RS34410"
                     /old_locus_tag="BT4G5_34415"
     CDS             6946..8178
                     /locus_tag="BT4G5_RS34410"
                     /old_locus_tag="BT4G5_34415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071621.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003916 - DNA topoisomerase activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="WP_228220170.1"
                     /translation="MFCLSDSKENFQLRNEEPPTSNTGVPGCFDIYTIPCLDWVQVTFK
                     SVQNSQENARKIINKISSFFGIDDFLFEHFDEGLHGYRKSYKFLGQNTFQLLFDAPSNM
                     GIHLILTGSMLKLLRSDYGTSDIGLLKFLSSISKEFHFSRVDVAKDDTSGSVSIKKIAR
                     YIKDGNLTTRFRGGHQIKKFKLIGEEEEDKLQYVPDGETWYLGSRSGTQFRFYDKKAQM
                     NADDLLHWTRCELQLVDDAATNFVKNVIVLDKPKFEKFCYSVFLTYVDFKKTTGAKHMK
                     NRDSAKFWADFLDSTVEKVKLGSRKKKKSLDDVNPNVLWEKLLDGDADFYFESMSQKEK
                     DKFDKWFYEQISSVLYLRALKHEEGIEEFYKKLIHWGETRVDQKKVEAVGVQLLMSERL
                     KRIKEKESPID"
                     /name="replication initiation factor domain-containing
                     protein"
     gene            8870..9910
                     /locus_tag="BT4G5_RS34415"
                     /old_locus_tag="BT4G5_34420"
     CDS             8870..9910
                     /locus_tag="BT4G5_RS34415"
                     /old_locus_tag="BT4G5_34420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001085408.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="WP_042991732.1"
                     /translation="MAKKNQDEITGKLQPKKKQNIKIYEFIERKMSESGRELFKSCSTF
                     NEFVATKDKKKKKRVKGNDCKNRFCPICAWRKAGKDAVKIATMMEAIKIEEKKEFLFLT
                     LTTPNIKADMVKSEIDRFNKAFNKLFKRRNIQRSIKGYIRKLEMTYDKERFITKGMYKD
                     RKAYYDKRGLKVDDHNPNYDTYNPHFHVLLCVDKNYFKRKELYIKQEEWLEMWREVTDM
                     PEITQVHIQKVELIREGNAVAEVAKYSAKDYEMSVSQDVFDVFYLALKGRQLIVYGGLL
                     KDYAKKYEDGELDKYKSKDKNEYYYRLIAIWNKDLMKFEQEYQELTESEKQEYNGHLID
                     EVDVEA"
                     /name="protein rep"
     gene            10060..10215
                     /locus_tag="BT4G5_RS37535"
     CDS             10060..10215
                     /locus_tag="BT4G5_RS37535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_021729289.1"
                     /translation="MGRKRIDPDEKKTRLNVAIKKKYVDLVNQEENTSQFVEDAIVKYL
                     KENKKI"
                     /name="hypothetical protein"
     gene            10359..10622
                     /locus_tag="BT4G5_RS34420"
                     /old_locus_tag="BT4G5_34425"
     CDS             10359..10622
                     /locus_tag="BT4G5_RS34420"
                     /old_locus_tag="BT4G5_34425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001123562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_021729290.1"
                     /translation="MPQAIIEGQYLSSSIKKSTFNGVEKSFVQLDVYQPESTDSEKTVV
                     VKCDDLELINHFKDTKMGMPIKAKVSINAYQNKAYFKLVNLA"
                     /name="hypothetical protein"
     gene            11259..11411
                     /locus_tag="BT4G5_RS36900"
     CDS             11259..11411
                     /locus_tag="BT4G5_RS36900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001113828.1"
                     /translation="MPEFGFRPSMSQLFGNFHMNWSTMMPLLVILFGILFGFFVAHLVK
                     DKFDD"
                     /name="hypothetical protein"
     gene            11432..11590
                     /locus_tag="BT4G5_RS36905"
     CDS             11432..11590
                     /locus_tag="BT4G5_RS36905"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000425805.1"
                     /translation="MEMPKISLTYNLADVANGLTNWLGAYWPIIAFSVAIPLTFLVAFN
                     TKDLFTR"
                     /name="hypothetical protein"
     Typing          7157..8190
                     /name="rep_cluster_485"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="96.908"
                     /coverage="99.0"
                     /evalue="0.0"
     Typing          8736..9892
                     /name="rep_cluster_617"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="90.917"
                     /coverage="99.0"
                     /evalue="0.0"
     Typing          6947..8175
                     /name="MOBT"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="99.756"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 gataaaccaa tgactcctga taagccaatg gaaaaggaag acatgaagcc tgataaacca
       61 atgactcctg ataaacctat ggatcgagag ggagaaatga aaaaagataa tgatatgaaa
      121 caagataagc caatgactcc ttgggaagaa atgaaaccaa gtgacgaagg gagtgaactt
      181 tgttggcatg tagtaaatgg aaaatgcgga taaagaaatt tttattagta gtgcctttat
      241 tacttggaat tttatttata ggtgatacaa gtgcatttgc tgaggtttct cgtgcaagtt
      301 taggaaatga tttgctgaag ggtgtatcag gtagtatgtg tggttctaca gtaaccaaga
      361 taactgatgg taatccttca acaggagaaa ctttgtttaa gacttgtcgg gaaattcgat
      421 ttaaattacc taaagtatca aatgtatcag gttttttata tataaaaaca aataagtgga
      481 ctagtgataa attggctatt gattttaaaa aagtagatgg tcaagttaaa actattacgt
      541 ataatcaggc ttctgttaat tcaaataatt atattcaagt atttgttaag gacgtttctg
      601 aagtagtgtt gaggaatttt gatgatacag gtgcaattga gattatgtca tttgaattat
      661 atgagggtaa cggagatgaa tttttttatg aggatataaa agaattacag ccgactatta
      721 catatgattc tgttactttt tcttataaga atcccaaaat agattttggt tatttaagaa
      781 tttatagaga tggtaagttg attgttgata attttaaatt agagcaattt aaagataagg
      841 aattaagtcc taacactgaa tacaaatata aatttgttgc tgtatcatct gatggtattg
      901 aatctaaggg catagaaaaa gtaattaaaa ctgatgaaaa gcctaattta gctaaaccaa
      961 ttaaaccatc taatcctacg ataacaccta aagatggttc tctaattgtt aatttaacga
     1021 attatgatgc tggtgtgaaa gtaaagggtt atcacattgt tgtagatgga aaacaggtaa
     1081 atgattcatt ggttacagca cgatcatatg cgattaccgg tttgaaaaat ggacaatcat
     1141 atcaagttca gattaaagct gtatcggctt ggaatataga gagtgattta agtaattctg
     1201 ttccaggtat tccacaagtg caagtaatac ctgatatcgc ttttaatttt ggtctttctg
     1261 atttaatgga atctattaaa aattggttcg gtggaatttg gcctatcgtt gcttttagta
     1321 ttgctattcc attaacgttt attgttgcgt ttaacacgaa gaagttattt ttaaggtagg
     1381 tgcttagttt gatacaacca gttacatcta aggacttaat acaatttctc cagtatgcat
     1441 ttcatgctgg ggaaaacgta ttatttctag cgtttgtatt aatgattaca ttctctgttg
     1501 ctataagcat tagaaggatt atggtgggtt ataagcaatc atgatggaga agtttgttaa
     1561 gttcttaaaa ggtggatttg aagcggttat aaagtcgtta aaaacgttta ttgatttttt
     1621 agctacacca tttcaatatc tattggattt tttaaaagga atcttttatt tcatagaaaa
     1681 gctgtttcaa gttgtagtag caattataaa attattcgtt gccttgtttc agtttttagg
     1741 tgctgtaata gcgggattct ttaaaacttt atttctatgg gtacaaccta attttgatgg
     1801 tgggaatgta tcttttccta gtgcttcgat gaagggattt aagacagcga cagatatatt
     1861 acttcctact ggtttgttaa cagtagttcc gatggttgtc acatgtttta tttggtactt
     1921 gtttgttaaa aagctcatgg atctattcag aggtggtcat cattaatgaa tgcgttaatt
     1981 gatacaatat ttaatcctgt tcttggttgg cttgcgcaaa tggcaaagta tttaaatgat
     2041 ttaagcgtac cagcaagtcg tcctttgcga attagtgatt accttggagt gtttgcttat
     2101 ctatacggtt ggacaaccgt tataacgacg ttatttgctt tagttttcgt atattttgtt
     2161 tgctatatca tcatgactta cagtagttta tttattcgat ttaaagatac ggttaaatgg
     2221 tggtgacgat attggatatt ataggacaag ctattttatt aatatttttt acgacaattg
     2281 tttcttggat ggtaatagat acattgaaat tctttagagg tatagaagaa tgatttattt
     2341 gatattggga gtcgttagtt gtttattaat tttagtttgt gatgcaactt cgaaaaagga
     2401 gagttaaaaa tgcaggcttt taatgcaatg tttgagttat caagtgcgat ttgtttatct
     2461 gtatttctat ttatagtgtt accttgtatg tggttaaaaa gaaaatggaa ttaaaaagag
     2521 agagtgattg aaatgttagc taaaacgaaa cgaaaagtac agccacaatt tgaaggacat
     2581 agagcgttaa ttattaagga agagggtaca tgcactgtag aacaggttat atcgtttgat
     2641 tcggagattt tagaaacgag tacagccatg ttaccacgtg ataatgaatt gagattactt
     2701 gatgataatc acggttatgt gtatcacatt tataatttag aaaaaccggc aagaattgaa
     2761 gcggaaaata ttaaaagatt acgacgatct agtgcgttaa aagggatttt tgaatttgaa
     2821 acaggaaaaa aacaatttga tttaattggt tttatgccat gggtaattat tgttttacta
     2881 gctattttta aataatgggg tgaactgaat gagtgaagtg actttagaaa aaacagttgt
     2941 agaagaagtg ttaccagatg ttcaagacat aatgaaagaa gaaattttag aagaagatac
     3001 ttcaagtgaa agtattgaaa cggttcaatt atttcaatac atgaaggaaa attcagtgcc
     3061 tttgaatgca tctcagatga aaggtatttt attgcttaat gagaatggat gtaaagatat
     3121 agctgattat gttatttctg taaaaaaaca gagtttacca cttgccttct atgaaaaggt
     3181 tctaaaaata ttaactatgt ttgacagaat taaaggtaat gcgaaattaa gtcatttact
     3241 gaaagcgaat gcgaatccat cattatcact ttcagctaat agtgcaaaag tagtgaaagg
     3301 aaatgaactt gcatgaacgt aatggtcttt gaaggtcctc ttggaagcgg taagacatta
     3361 ggaatgacat tgtttgcaca tcactttaaa cagaaaagta attgcgtatt gtatagcaat
     3421 tatggcgtag ttggttcaaa gccatttact gaaatagaac attttaaaaa tattgctcaa
     3481 gaaaaatcta caattttaaa tttagatgaa gctcatattg atttggatgc tcgaagtttt
     3541 tcgagtaact cggttaaatt cttttctcaa gtatcgtatt atcttcgaaa attacgttgt
     3601 acgttgttta ttgcttcgcc tagctttgat gatttagatt cacgtataag aggtattacg
     3661 aacgttcttg ttaaggtttc aagtgataaa aaatactttt actatacgat gtatgacatt
     3721 caatctaaac gttatttaaa gagaatgcgt ataagtaaaa agaaagcttt tgttgttggt
     3781 tcaaaaattt atgatacaag tgcaatggtt tcgccagtaa aagttccaga aaaacgccaa
     3841 gactttatgg aatttttaga agcgttgaag acgaccgccg aagagtacgg acgccagtac
     3901 aagcattcag cgtaagctgt atgcgcggta caggcgggag gacttcataa gattataaaa
     3961 attatatcaa ggaaggaacg ttgttatggg gattttaaag aagaaaagat ttcgtgaaga
     4021 agtgaaaaga ataaataaag cacatgaaga gatgaaaagg tttctagatg tactcatgga
     4081 tcgctatgga ttagatgaag aagaaataaa taattgtgaa gtaattaaac atcattttga
     4141 caatttagat ttgatgttta gtcaaatggc taagtagatg attgaatata ttgtaggtgc
     4201 tagtgtgctg tggttaggtt cgatagtgat tgcttattta ttagttagtg atatggatat
     4261 ttattagaga ggataaatag ttgaaatgat acatgtggat tggttgaaaa gtatggcgag
     4321 agatggactg ttttatggtt cattcattgc tgtaattgtt ttcttgttaa attggtttac
     4381 gggttaggtt ttaaaggtat tccttcgctt ttgaggttgg agattggctg gggtgtgggg
     4441 ctagccccgc aaagcgtaat gggtaaatag aataaaagaa aatataaagg tcggtagtac
     4501 aagcgtttag gctcgtataa tggataggca agttgatagt taaatatatt cacttttgag
     4561 tttatcgact tggcgatgaa gaaaaacgag cctaaaaaag ttatgcaaga atgtagcgca
     4621 gcgaaaaagg tggagatttt atgaagcaga gcgtaagaaa atactacctg tttcttgttt
     4681 aaccttttag caaatacaga tagagggttg ttttgatgga aaatgttatt gttacgttgt
     4741 ttggtactct agggatttgt ttcttgttta aaggcatgtt agacacgtta aaagaagggt
     4801 gatatgtaat ggatttgcct atttgtaatg aaaaagaggt aactgtttta tctaaaacgc
     4861 tgaaatattt gaggagtgat caatctaacc aagttaaggt acataaggag tacttagaag
     4921 acagaggttg gatatttgat gatttaagtt atatagatag tcatatctat gtagtttata
     4981 aaaaagaggt tgtgaagcgg aataaggcgt tttaaggggg atatatatgt ttaaaaagtt
     5041 ttatcgtgaa tatattcatg tattgtttaa tattgttgcg atgttttttt attttagttg
     5101 gtgtttagtt ggtactgaat ttaatttatt aactctaata gcaattggaa ttgctatttt
     5161 tatctttgtt aagtatgtat ctatggatag gaaatttgtt aatgaaaata tagataaatt
     5221 aaaagataaa aagatgattt ttaggaagta tgctataagt ggtgaaaata ttggatatgc
     5281 agtttttaca aattttttat tgtttctttt gtatttgggg atatcggtat attttaagga
     5341 tttaagtgta atatcgcttt tgtttgcttt tattcttaat gttagtttgc ttatgttgac
     5401 tcttagagta atgagtaaat ttagtttaaa gaatagtaaa gtttaagagg tgtatatatg
     5461 tttgctagat atcgtagtca agatgatgag tttatgtcac aacttcaatt tttggcttta
     5521 ggtgctatta tgacatttct aattaaattt ggttgtattt cacctgaagt taatatgtta
     5581 acgttatttg ttctttttgt tattttaatt ggaatctatt atctttttgt acttttatta
     5641 acaaagtatt tttatagatt tctttctaaa caacatgata agttgcatgc ttatttatgt
     5701 aataagtatg gtgaaaaaat agcaaataga gttggtttgt catttcttat aattttaatt
     5761 gtggggatgt tgattgtatg tttgctgatt taaagttgaa ttttaaattt tggttaattg
     5821 tagtttttga tatatgtatg cttgcaatga tctgtgttgt tacaacaaag tatgtatctg
     5881 atatatatag tgatttgttt attttcacga caggattttt aatactgtta atttggtatt
     5941 ttgttagagt ttatttgata gatattgtta aaagttttgc tagtaaaact taatattatt
     6001 atttaattgt aaccttttgt ataaaatatt tccggaaaaa tatatgcaaa aggttgcttt
     6061 tgcatatgcg aaatgttatt atgcatatat aaagttttag gaggttgtga aatgactgtt
     6121 gttaaagagg aaagaaagaa tcgtgtattt cgttttactg atacggaagt ttctttaata
     6181 gatgaattga ttgatattga aaatgataaa agaatgacta ttgcaagaga aaagaattta
     6241 aaatataaag cattaaatcg tacaagtttt attttatata tggctgaaga aagaagacgt
     6301 aaatatgaag aacaagggga gttttaagtg gttttctctt aactagttaa taataatagg
     6361 gatagagtcg cacttttttc aaattataaa ttggaggttg taaccatgga agaattgtta
     6421 cataaaatta ttgataaatt agataagatt gataaggata ttcaggagat taaaacggat
     6481 ttgaaggctc atcgtattga aactgatgat aattttacta agttatatca tttggttgag
     6541 gaaaaagatg ttgagattga tgtattgaat aaacgtctat ttaagaacga ggcgacggtt
     6601 gaacgtatta agagggaaaa gcattaggag gaaattgttg atggcatata gttattgtgt
     6661 ggattgtgag agtgtgtata gctgtgaaga tgaaaagtgt tgttgtggaa gtaaaaaacg
     6721 ttctgttgat tgggaagaat ttgcttttat tatgggttat ccgttatatc ctgttaagaa
     6781 aaaatatggt gtttttcatt tagatttatc taaacgttta gatgctgatg ctttatgtga
     6841 tcttaaagca gataatccag aactttttta ttatgagttt aaaggttgga aagaaagaga
     6901 attgaaaaag agaaattaat aataaatata ttttggagtt agtgggtgtt ttgtttgtct
     6961 gattcgaagg aaaatttcca gttgagaaat gaggaacccc cgaccagtaa cacgggggtt
     7021 cccggctgtt tcgatatcta cactatccct tgcctagact gggttcaagt cacttttaaa
     7081 tctgtacaga attcacaaga aaatgcgcgg aaaattatta ataaaatttc cagttttttc
     7141 ggtattgatg atttcttgtt tgaacatttt gatgaaggtc tacatgggta tagaaaatcg
     7201 tataaatttt taggtcaaaa tacttttcag ttattatttg atgcaccttc taatatgggt
     7261 attcatttaa tacttactgg atctatgttg aaattgcttc gttctgatta tgggacaagt
     7321 gatattggat tgttaaaatt tttgtcttct atttctaaag aatttcattt ttcgcgtgtt
     7381 gatgtcgcta aagatgatac gagtggtagt gtatcgatta aaaagattgc tagatatatt
     7441 aaagatggaa atctaactac tagatttaga ggtggacatc aaattaaaaa atttaaattg
     7501 attggtgaag aagaagaaga taaattgcaa tatgttcctg atggtgaaac gtggtatttg
     7561 ggttctcgtt caggtacaca atttcgtttt tatgataaaa aggctcaaat gaatgctgat
     7621 gatttattgc attggactcg ttgtgaatta caacttgttg atgatgcagc aacaaatttt
     7681 gtgaagaatg ttattgtttt ggacaagcct aaatttgaga agttttgtta ttcagttttt
     7741 cttacatatg ttgattttaa aaagactact ggtgcgaagc atatgaaaaa tcgtgattcg
     7801 gcgaagtttt gggctgattt tttagatagt acagtagaaa aagttaaatt aggttctcgt
     7861 aaaaagaaaa aatcgttaga tgatgttaat cctaatgtgt tgtgggaaaa attattagat
     7921 ggagatgctg atttttattt tgaatctatg agtcaaaaag aaaaagataa gtttgataag
     7981 tggttttatg aacaaatatc atcagtttta tatttgagag ctttaaaaca tgaagaaggt
     8041 attgaagagt tttataaaaa attgattcat tggggtgaaa ctcgagtgga tcagaagaaa
     8101 gtcgaagcgg ttggcgttca gttgcttatg tcagaaagat taaagaggat aaaagaaaaa
     8161 gaatctccta ttgactagat agaagattct ccgatctctt tagtaatagc gttactaaag
     8221 ggatcctaca gacaaaaaaa tgattattaa cgaatgtact tgtattatac atttaaagaa
     8281 tattttcgtc tattttaata gttggtttca tgtttctact gggggctagt aacaccccag
     8341 tagaaaatac aggtcaatcg cccccaaacg cttgtggctc tagggttcgt ccctctttgt
     8401 ttttttcacg gttcttttaa aaaaacaggc aaaaaatttg tggtttttat ttttttatat
     8461 tgtattcatt ggagtggtgg atgaaaaaag tggagaatta taaaagaaga aaacctcact
     8521 gttgaaagta ttgaggaaaa tagtatttta gcaaatattt atttgtaatc cttttgaatg
     8581 tttttatcat ttagaaggtt tttttatagt ttttcggtta cgaaaaatcg ggtttcttct
     8641 ttctttaata cataggtaac tatttccgca cggaaattga tgcctatgta tgggtttagc
     8701 ccttgtgtat caagggtttg caaaaaaaaa agacttgctt ttctaggcgg atagatttaa
     8761 tgttttaagt gactagctaa aaacaaaatc atccaagaaa ggagcaagtc cgaaaaaagg
     8821 ggttcgtgta ccctttttta tgaaattcag ataggactaa tatatcaata tggcaaagaa
     8881 aaatcaagat gaaatcactg gtaaactaca acctaaaaag aaacagaata taaaaatata
     8941 cgaatttata gagagaaaaa tgagcgagag tggtagagaa ttgtttaaat catgtagcac
     9001 ttttaatgag tttgtggcta caaaggataa aaagaaaaag aaacgagtaa aggggaatga
     9061 ttgtaaaaat cgtttttgtc cgatttgtgc ttggaggaaa gcaggaaagg acgcagttaa
     9121 aatagcaacg atgatggaag cgattaagat tgaggaaaag aaagagtttc ttttcctcac
     9181 attgacgacg ccgaatatta aagctgatat ggtaaaaagt gagattgata gatttaataa
     9241 ggcttttaat aaattattta agagacgtaa tatccaacgt tctattaaag gttatattag
     9301 aaagttagaa atgacgtatg ataaagaacg atttattaca aagggaatgt ataaagatag
     9361 aaaagcatat tatgataaac gtggattgaa agtggacgat cataatccga attatgatac
     9421 atataatcct cattttcatg tgttactttg tgttgataaa aattatttca aacgtaaaga
     9481 actttatatt aagcaggaag aatggttgga aatgtggcga gaagtaacag atatgccaga
     9541 gattacgcaa gtacatattc aaaaagtaga gttaataaga gaaggaaatg cggttgcgga
     9601 agttgcgaag tattcggcaa aagattatga aatgtcagtg agtcaagatg tatttgatgt
     9661 gttttattta gctttaaaag gtcggcaatt aattgtgtat ggtggattgt taaaagatta
     9721 tgcgaaaaaa tatgaagatg gcgaattgga caagtataag agtaaagata agaatgagta
     9781 ttattataga ttaatagcaa tatggaataa ggatttaatg aaatttgaac aagagtatca
     9841 agagttaaca gagagtgaga agcaagaata taacggtcat ttgattgatg aagtagatgt
     9901 ggaggcgtaa tataaaaaaa gaaaaaagag tattagaaaa aaagtaaggg agctggctgt
     9961 tgtattaagt cagtttcctt tttttattta cagttagtgt taaaatttta atgtataaaa
    10021 tgtaggatgt ataggtaaaa ttttgtagag gtgtaataaa tgggtagaaa gcgtattgat
    10081 ccagatgaaa aaaagactag attgaatgtt gctattaaga aaaaatatgt tgatttagtt
    10141 aatcaagaag aaaatacatc ccaatttgtt gaggatgcaa tagtgaagta tttgaaagaa
    10201 aataaaaaga tttaattttt ttttttggaa aatacttgtt ttctgttccc tttttttgct
    10261 ataatcagaa cgtaaaatct tgctacgaat aaatgttcgt tcaggatatt tgattttata
    10321 ttatattttt tcataaaatt taaaaggagt gtaattttat gccacaagca attattgaag
    10381 gacaatactt aagttcaagt attaaaaaat caacttttaa tggtgttgaa aaatcatttg
    10441 tacaattgga tgtttatcag cctgaaagta ctgatagcga aaaaacagtt gttgttaagt
    10501 gtgatgattt agagcttatt aatcatttta aggatacgaa aatggggatg cctattaaag
    10561 caaaggtttc tattaatgct tatcaaaata aagcatattt taaattggtt aatttagcgt
    10621 aaaatcttta tattaagaca aaaaaatgaa tgtgaatgaa tgtgatttta tgttggataa
    10681 aatcgattta aacgaattgt acaaaaccat ttcggaaatt atgcctaact acttagtaca
    10741 gactaagaac ggtagttttg cagttttcca gacacttacc tatggtgata tgttaattag
    10801 tttcttgtta ttgctaatct tgttggtgtt gacattcaac tggatatgga gtgctttacg
    10861 atgatcgagt ttaatttaga aaacttgttg aatcaatatt ccttgtttgg attaccattt
    10921 ttattaatta tcgtgttcac attgctgaaa gattggcggt ttgatagata atgaatgatt
    10981 tagcgtttct agatatgttg tattggttct tcatgaataa ttcagttgta ttatattcgt
    11041 taggttttat aacctttctt gtgttcgtaa taatgatgtt caccaccgtc aaagcttggg
    11101 gtgatggcta ttagttttag catggacgtg ggaagaatct tgcagtatgc cttcaacatg
    11161 tttagttcag tgttaccagt gatttattta ttcattggtg gggcgtttgc tatctactgt
    11221 atcggtaaag tgtacaacac ctttaggagt tgatttcaat gcctgaattt ggattcagac
    11281 catcgatgtc tcaattattc ggtaactttc atatgaattg gtcaacaatg atgccattgt
    11341 tagtcatttt gtttgggata ctgttcggat ttttcgtagc gcatttagta aaagacaaat
    11401 ttgatgattg attaactagg aggaatttat tttggaaatg ccaaaaattt cattaactta
    11461 taatcttgca gatgttgcaa atggtttaac taactggtta ggcgcttact ggcctattat
    11521 cgcattctct gttgctattc cgttaacgtt cttagtagcg tttaacacta aagatttatt
    11581 tactcgttaa tcatcaaaaa tcactcctta aatagcaaga agttaactat aaatttaata
    11641 aaacaatcaa atagctgggt ggatcgccta gctatttttt gttaggaagg attgatatga
    11701 aaaaagcagc cataattttt ttatgtacat tttgtattat ttttcgtaca gttcctgtct
    11761 ttgctgatac gccatcattt caaatggtag gaagtaaagg tgtttccata gaaaataaag
    11821 ggcttgttgg cggttattat agtctttcgt taaagattag tgatgctaaa gacgtagtga
    11881 cgtttcaatt gagtgagttg atgctcgtta atgattgtag ttttaatttt ggactagtga
    11941 aatggactag gccgtcacaa gagaagaatg agtttgatat taaagtcaaa gaaaatggaa
    12001 catatgcttt ttacgtgttt gtgaatggga aagttaaagg atatgttcgt tttaaaatta
    12061 aaggatttcc taaaaatgct gaaggtgctg gagtaactca atattggggg caaggtgcaa
    12121 agtattatga acttcctgaa gaacatgtaa atcctgagga ttttcgagac aaagatggag
    12181 aaaataatgg aatttgcgtg aatgaaaaaa tttctgatga taaaccaggt ggttcaggag
    12241 atatagaaga accaaaagag gataataaac cgccagttga aggcggtggc ggttctgata
    12301 aagctattaa agaagcttta gataaaatta caagtgcagt aaatgaaatt tcaaagaata
    12361 cgggtgaaac ggctaaaaat acaggtgaga ttaaaaagaa caccgatgaa atagcaaaga
    12421 acacaaaaga aatcgcggat gctgttaagg atattaggga taatttgaag attcctgacg
    12481 atatggattt gtcgattaaa cctgttcttc ctgaggacat aaagcctgat aaacctaaac
    12541 aacctgataa gccttttgaa gacaaacaag agcactttaa agagggtgaa caagagaaac
    12601 cacctgacaa acttcctgtt gctcctgggc ccgccgaatg ttggggggat gtttgtaaag
    12661 ataaagataa tcagaaagaa gaagatatga agaaagataa agatatggat aaagaagaac
    12721 caatgaagcc tgataaacca atggaaaagg aagacatgaa accagaaaag ccaatgactc
    12781 ctgataagcc aatggaaaag gaagacatga agcccgataa accaatgact cctgataagc
    12841 caatggaaaa ggaagacatg aagccc
//
