LOCUS       NZ_CP007177            27068 bp    DNA     circular CON 03-MAR-2024
DEFINITION  Staphylococcus aureus USA300-ISMMS1 plasmid pUSA01-ISMMS, complete
            sequence.
ACCESSION   NZ_CP007177
VERSION     NZ_CP007177.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN03081531
            Assembly: GCF_000568455.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus USA300-ISMMS1
  ORGANISM  Staphylococcus aureus USA300-ISMMS1
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 27068)
  AUTHORS   Altman,D.R., Sebra,R., Hand,J., Attie,O., Deikus,G., Carpini,K.W.,
            Patel,G., Rana,M., Arvelakis,A., Grewal,P., Dutta,J., Rose,H.,
            Shopsin,B., Daefler,S., Schadt,E., Kasarskis,A., van Bakel,H.,
            Bashir,A. and Huprikar,S.
  TITLE     Transmission of methicillin-resistant Staphylococcus aureus via
            deceased donor liver transplantation confirmed by whole genome
            sequencing
  JOURNAL   Am J Transplant 14 (11), 2640-2644 (2014)
   PUBMED   25250641
REFERENCE   2  (bases 1 to 27068)
  AUTHORS   Altman,D.R., Sebra,R., Hand,J., Attie,O., Deikus,G., Carpini,K.W.D.,
            Patel,G., Rana,M., Arvelakis,A., Grewal,P., Dutta,J., Rose,H.,
            Shopsin,B., Daefler,S., Schadt,E., Kasarskis,A., van Bakel,H.,
            Bashir,A. and Huprikar,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-FEB-2014) Genetics and Genomic Sciences, Mount Sinai
            School of Medicine, 1425 Madison Avenue, New York, NY 10029, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 1.4
            Genome Coverage                   :: 506x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/03/2024 05:41:48
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,992
            CDSs (total)                      :: 2,910
            Genes (coding)                    :: 2,819
            CDSs (with protein)               :: 2,819
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 48 of 91
            Pseudo Genes (incomplete)         :: 44 of 91
            Pseudo Genes (internal stop)      :: 19 of 91
            Pseudo Genes (multiple problems)  :: 19 of 91
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP007177.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..27068
                     /organism="Staphylococcus aureus USA300-ISMMS1"
                     /mol_type="genomic DNA"
                     /strain="USA300-ISMMS1"
                     /db_xref="taxon:1458279"
                     /plasmid="pUSA01-ISMMS"
     gene            232..1215
                     /locus_tag="AZ30_RS15030"
                     /old_locus_tag="AZ30_14185"
     CDS             232..1215
                     /locus_tag="AZ30_RS15030"
                     /old_locus_tag="AZ30_14185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_001181107.1"
                     /translation="MQNQYFTVQENYKERFYQIPKVFFTSENYKNLTNDMKIAYAILRD
                     RLNLSIKNSWVDEDGNIYFVYSNEKLMEILNCKKEKLTKIKKGLENDGLLIQKRRGLNK
                     PNILYLMKPIVTERDIYKIEKEENDVEPYGEKEVRKSNVQKFENRTSRSSKIERPEVRK
                     SNTNDTDFNDIDFNDTENNDMNDLNDIKYKNEISNHSNHSNQFTHNFDDKEMLLQEFPE
                     QLTNYLLKYDYRDLEIIKAVILKAKKSFNSRHEDMHYMLEDIEDEILTSLKRLKKAIHD
                     RGVKGQKETIKSMQAYLMQTILTELEETHALYMRRKNMKQYNIFNQ"
                     /name="replication initiator protein A"
     gene            <1235..1524
                     /locus_tag="AZ30_RS15955"
                     /pseudo=""
     CDS             <1235..1524
                     /locus_tag="AZ30_RS15955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009384749.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            2071..2220
                     /locus_tag="AZ30_RS16275"
                     /old_locus_tag="AZ30_14195"
     CDS             2071..2220
                     /locus_tag="AZ30_RS16275"
                     /old_locus_tag="AZ30_14195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000695366.1"
                     /translation="MKIKTFATFTHRQLDKQVNRFLKNDIHVLEIQTHSNWLYISAIVF
                     YEDK"
                     /name="hypothetical protein"
     gene            complement(2388..3080)
                     /locus_tag="AZ30_RS15035"
                     /old_locus_tag="AZ30_14200"
     CDS             complement(2388..3080)
                     /locus_tag="AZ30_RS15035"
                     /old_locus_tag="AZ30_14200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative immunity/bacteriocin fusion bifunctional
                     protein"
                     /protein_id="WP_000691527.1"
                     /translation="MKIIKLFSIISLFLLVFSANFSNAYANEEQKSSLLENQKEKLKSK
                     NIEVSQMTKKEISFLEQLQNKNEDMQKFEKQMKKEGFKKIKLEDKNSKLKYLATEANDK
                     NAYGYIANNAYKNEKTKEIVVSETIYDNYNKKITKFIAEKRSMTENKEGKILINKNYVE
                     YKAEKVDKNRPVTYAGFKWNGKAFACSMAGLYACAHYCGVWAIVNPIAGGVCEAVCGTA
                     FAAGCSVG"
                     /name="putative immunity/bacteriocin fusion bifunctional
                     protein"
     gene            3190..3384
                     /locus_tag="AZ30_RS15040"
                     /old_locus_tag="AZ30_14205"
     CDS             3190..3384
                     /locus_tag="AZ30_RS15040"
                     /old_locus_tag="AZ30_14205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001004925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001004925.1"
                     /translation="MNENLEKYIKSLPLLGLLISILLIVLFFFILDVDEDLFVVFLYCL
                     LPLIVNLSIYGFYVFVKRK"
                     /name="hypothetical protein"
     gene            4500..5117
                     /gene="cadD"
                     /locus_tag="AZ30_RS15045"
                     /old_locus_tag="AZ30_14210"
     ARG             4501..5114
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            5136..5483
                     /locus_tag="AZ30_RS15050"
                     /old_locus_tag="AZ30_14215"
     CDS             5136..5483
                     /locus_tag="AZ30_RS15050"
                     /old_locus_tag="AZ30_14215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119690.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNHEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            5640..5732
                     /locus_tag="AZ30_RS16165"
     CDS             5640..5732
                     /locus_tag="AZ30_RS16165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(5904..6875)
                     /locus_tag="AZ30_RS15055"
                     /old_locus_tag="AZ30_14220"
     CDS             complement(5904..6875)
                     /locus_tag="AZ30_RS15055"
                     /old_locus_tag="AZ30_14220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="WP_000481279.1"
                     /translation="MFNAVVVRKSASNVSYKVEKVDESHLSKGDVLVKVVYSSINYKDM
                     LALQYKGGVIRDYPMIPGIDFAGIVESSSNDKFKEGDNVLVTGYDVGVTHTGGFSEYAQ
                     VPGEWIVPIPQEMSIKESMVYGTAGFTAALSIFELEKYGMNIKSQPEILVSGATGGVGS
                     VAIQILHKIGYENITAIVRKEKQIEIAKKLGAKQVIIIEDDNKPLKKGIFDYFLDTVGS
                     NVTLYGLKRLNYQGVATVCGNVAGNSLNANILPFILRGIKLIGIDSVYVDHNIREDIWS
                     KLANEWNIGNSLLYNEIGFEEFYKTIDQLLKGQHLGRTILKV"
                     /name="oxidoreductase"
     gene            6999..7418
                     /locus_tag="AZ30_RS15060"
                     /old_locus_tag="AZ30_14225"
     CDS             6999..7418
                     /locus_tag="AZ30_RS15060"
                     /old_locus_tag="AZ30_14225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418034.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_000418035.1"
                     /translation="MELDNCINYLLSTSQNRVFKHFKSLLSPYNITPAEYGVLNCLINS
                     NLNTPKAIGNTLNLEPSTISGILDKMSKKDLITRQTDNENRRTVLINSTNKAKDLWPTL
                     EKKAYQLNNHYFANLTNEETVVFKKILLKINKTTF"
                     /name="MarR family transcriptional regulator"
     gene            complement(7944..8789)
                     /gene="blaZ"
                     /locus_tag="AZ30_RS15065"
                     /old_locus_tag="AZ30_14230"
     ARG             complement(7948..8789)
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            8896..10653
                     /gene="blaR1"
                     /locus_tag="AZ30_RS15070"
                     /old_locus_tag="AZ30_14235"
     ARG             8897..10650
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.38"
                     /coverage="100.0"
     gene            10643..11023
                     /gene="blaI"
                     /locus_tag="AZ30_RS15075"
                     /old_locus_tag="AZ30_14240"
     ARG             10644..11020
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="98.41"
                     /coverage="100.0"
     gene            11287..11865
                     /locus_tag="AZ30_RS15080"
                     /old_locus_tag="AZ30_14245"
     CDS             11287..11865
                     /locus_tag="AZ30_RS15080"
                     /old_locus_tag="AZ30_14245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690624.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690637.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLNLLKTLYDNGTPI
                     KTIAEQWQVSRTTIYRYLNKLEAKENKNK"
                     /name="recombinase family protein"
     gene            complement(12088..12273)
                     /locus_tag="AZ30_RS15085"
                     /old_locus_tag="AZ30_14250"
     CDS             complement(12088..12273)
                     /locus_tag="AZ30_RS15085"
                     /old_locus_tag="AZ30_14250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001037130.1"
                     /translation="MNKLEKWSLVFIIFTFLSSLALLYFKYNFSSVMPVLSLSILTILI
                     LLTSIITVVSVNDEDT"
                     /name="hypothetical protein"
     gene            12535..13209
                     /locus_tag="AZ30_RS15090"
                     /old_locus_tag="AZ30_14255"
     CDS             12535..13209
                     /locus_tag="AZ30_RS15090"
                     /old_locus_tag="AZ30_14255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105991.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(13378..13949)
                     /locus_tag="AZ30_RS15965"
                     /pseudo=""
     CDS             complement(13378..13949)
                     /locus_tag="AZ30_RS15965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /name="HTH domain-containing protein"
     gene            complement(14225..15019)
                     /gene="aph(3')-IIIa"
                     /locus_tag="AZ30_RS15100"
                     /old_locus_tag="AZ30_14265"
     ARG             complement(14229..15019)
                     /name="aph(3')-IIIa"
                     /gene="aph(3')-IIIa"
                     /gene_name="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(15112..15642)
                     /gene="sat4"
                     /locus_tag="AZ30_RS15105"
                     /old_locus_tag="AZ30_14270"
     ARG             complement(15116..15642)
                     /name="sat4"
                     /gene="sat4"
                     /gene_name="streptothricin N-acetyltransferase Sat4"
                     /tool="amrfinderplus"
                     /drug_class="STREPTOTHRICIN"
                     /identity="97.78"
                     /coverage="100.0"
     gene            complement(15639..>16274)
                     /locus_tag="AZ30_RS15975"
                     /pseudo=""
     CDS             complement(15639..>16274)
                     /locus_tag="AZ30_RS15975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009251744.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /name="aminoglycoside 6-adenylyltransferase"
     gene            complement(16415..17089)
                     /locus_tag="AZ30_RS15120"
                     /old_locus_tag="AZ30_14285"
     CDS             complement(16415..17089)
                     /locus_tag="AZ30_RS15120"
                     /old_locus_tag="AZ30_14285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105956.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(<17146..17322)
                     /locus_tag="AZ30_RS15125"
                     /old_locus_tag="AZ30_14290"
                     /pseudo=""
     CDS             complement(<17146..17322)
                     /locus_tag="AZ30_RS15125"
                     /old_locus_tag="AZ30_14290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499250.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016311 - dephosphorylation [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /name="undecaprenyl-diphosphate phosphatase"
     gene            complement(17336..18073)
                     /locus_tag="AZ30_RS15130"
                     /old_locus_tag="AZ30_14295"
     CDS             complement(17336..18073)
                     /locus_tag="AZ30_RS15130"
                     /old_locus_tag="AZ30_14295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000369394.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="WP_000369394.1"
                     /translation="MDNLLRTEFIKLKRSYMFLISILGTCVAPFMVVVASFISMRTKVP
                     TPNIVFKQLFEEVSLYHMLIIGPPLYGVIIAYLFGREYIEDTLKNLLIIPISRESFLVS
                     KIILLFLWIQTLSVIAWLLTLMLGMLLHFQGLSQSLIIDSFFTFVIGGVLLWILSPPII
                     ILSIYFKNYVPTIVLTIIITLINLMTANSEHRGLFPWAAVGDISRGTLPNTYPFLLSLI
                     IIIVTSIFSVIILFSYFKKTDIS"
                     /name="ABC transporter permease"
     gene            complement(18066..18995)
                     /locus_tag="AZ30_RS15135"
                     /old_locus_tag="AZ30_14300"
     CDS             complement(18066..18995)
                     /locus_tag="AZ30_RS15135"
                     /old_locus_tag="AZ30_14300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000074567.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016887 - ATP hydrolysis activity [Evidence IEA];
                     GO:0042626 - ATPase-coupled transmembrane transporter
                     activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000793446.1"
                     /translation="MKNLNNIIEINNLTKQYGSQIAVNNLSITVESGQIYGFLGRNGAG
                     KTTTIRMLLGLIKPTKGNIKIFEKEFESNKTEILKNIGAMVETPGFYSNLTAKENLTIN
                     AKILGIQKENAIEEVLEIVGLASEKVKLFKNYSLGMKQRLGIARALLHNPELLILDEPT
                     NGLDPIGIKEIRKLIKDLAQSRNITILISSHILSEIEQLVDKVGIIHNGVLLEEIMYED
                     LKKKNRQFISISVSDEEKVACLLETNFGIYDYKIKENGEFKIYSHIDRQQEINRLLVLN
                     NIDVFQMRVIEDNLETYFEDLVGGGTIG"
                     /name="ABC transporter ATP-binding protein"
     gene            complement(19111..19992)
                     /locus_tag="AZ30_RS15140"
                     /old_locus_tag="AZ30_14305"
                     /pseudo=""
     CDS             complement(19111..19992)
                     /locus_tag="AZ30_RS15140"
                     /old_locus_tag="AZ30_14305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015581923.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0000155 - phosphorelay sensor kinase activity [Evidence
                     IEA]; GO:0004673 - protein histidine kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /name="sensor histidine kinase"
     gene            complement(19989..>20366)
                     /locus_tag="AZ30_RS15150"
                     /old_locus_tag="AZ30_14315"
                     /pseudo=""
     CDS             complement(19989..>20366)
                     /locus_tag="AZ30_RS15150"
                     /old_locus_tag="AZ30_14315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019834602.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]; GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /name="response regulator transcription factor"
     gene            complement(20424..21098)
                     /locus_tag="AZ30_RS15155"
                     /old_locus_tag="AZ30_14320"
     CDS             complement(20424..21098)
                     /locus_tag="AZ30_RS15155"
                     /old_locus_tag="AZ30_14320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="WP_001105960.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            21572..23038
                     /gene="msr(A)"
                     /locus_tag="AZ30_RS15160"
                     /old_locus_tag="AZ30_14325"
     ARG             21573..23035
                     /name="msr(A)"
                     /gene="msr(A)"
                     /gene_name="ABC-F type ribosomal protection protein Msr(A)"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE/STREPTOGRAMIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            23137..24036
                     /locus_tag="AZ30_RS15165"
                     /old_locus_tag="AZ30_14330"
     CDS             23137..24036
                     /locus_tag="AZ30_RS15165"
                     /old_locus_tag="AZ30_14330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mph(C) family macrolide 2'-phosphotransferase"
                     /protein_id="WP_000196697.1"
                     /translation="MTRHNEIIKCAEKYQLHIQPQTISLNESGLDFQVAFGKDKHGVEW
                     VLRLPRRPDVYKRTKPEKQTVDFLQKNVSFEIPKWKVHAKDLIAYPKLTGKPAATIDPE
                     IQNYVWEIEHKPLPENFINTLAETLVDLHNIPEENINVQHINIKTIQEIKNDFQRRMNK
                     VKETYGVSDELWNRWKQWLENDELWPRHATMIHGDLHPGHIMVDNQANVTGLIDWTEAT
                     HSDPSMDFIGHHRVFDDEGLEQLITAYGKAGGEIWPRMKEHIIELNAVFPMFIAEFAME
                     SGESAYETMALKELGMKE"
                     /name="Mph(C) family macrolide 2'-phosphotransferase"
     gene            24522..25130
                     /locus_tag="AZ30_RS15170"
                     /old_locus_tag="AZ30_14335"
     CDS             24522..25130
                     /locus_tag="AZ30_RS15170"
                     /old_locus_tag="AZ30_14335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002474535.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000583528.1"
                     /translation="MIIGYARVSSIDQNLERQLDNLKTFGVEKIFTEKQSGKSVENRPV
                     FQEALNFVRMGDRFVVESIDRLGRNYDEIIETVNYLKEKDVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRV
                     IYHRVVEMLEEGKAISKIAKEVNITRQTVYRIKHDKGLS"
                     /name="recombinase family protein"
     gene            25376..25714
                     /locus_tag="AZ30_RS15175"
                     /old_locus_tag="AZ30_14340"
     CDS             25376..25714
                     /locus_tag="AZ30_RS15175"
                     /old_locus_tag="AZ30_14340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001049146.1"
                     /translation="MNLIPFIIILIFSCLWTAITNKYLPSETLDKKGQQDRYDERQRKM
                     FIEILAKSFIWIVYCMLFTLVLKFTGLSPSIEGSWFSQYPEIFFIIVALFLMLFNYYTT
                     NKKYTSKG"
                     /name="hypothetical protein"
     gene            25719..25904
                     /locus_tag="AZ30_RS15180"
                     /old_locus_tag="AZ30_14345"
     CDS             25719..25904
                     /locus_tag="AZ30_RS15180"
                     /old_locus_tag="AZ30_14345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011276570.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000797248.1"
                     /translation="MKNRIREYRKQKGISQETLSKELKVSRQTINAIENNKYDPTLTLA
                     FKLARLFDTTVDELFS"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(26131..26874)
                     /locus_tag="AZ30_RS15185"
                     /old_locus_tag="AZ30_14350"
     CDS             complement(26131..26874)
                     /locus_tag="AZ30_RS15185"
                     /old_locus_tag="AZ30_14350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843732.1"
                     /translation="MKSVKKLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESTTEDKQKKGSDNINFESKSDAQIVEILKNQIDTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNTR
                     QNVDAQEKTYTTNPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAKKEDVPANLND
                     NDSDIEEKSEETEPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     ARG             23138..24033
                     /name="mph(C)"
                     /gene="mph(C)"
                     /gene_name="Mph(C) family macrolide 2'-phosphotransferase"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             21573..23038
                     /name="msrA"
                     /gene="msrA"
                     /gene_name="msr-type ABC-F protein"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; streptogramin
                     antibiotic; streptogramin B antibiotic"
                     /identity="98.36"
                     /coverage="100.0"
     ARG             23138..24036
                     /name="mphC"
                     /gene="mphC"
                     /gene_name="macrolide phosphotransferase (MPH)"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="98.66"
                     /coverage="100.0"
     ARG             complement(15113..15630)
                     /name="SAT-4"
                     /gene="SAT-4"
                     /gene_name="streptothricin acetyltransferase (SAT)"
                     /tool="rgi"
                     /drug_class="nucleoside antibiotic"
                     /identity="97.16"
                     /coverage="95.56"
     ARG             complement(15937..16238)
                     /name="aad(6)"
                     /gene="aad(6)"
                     /gene_name="ANT(6)"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="99.0"
                     /coverage="36.23"
     ARG             complement(7945..8789)
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     Typing          1581..1728
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="5.980000000000001e-72"
     Typing          233..1215
                     /name="rep_cluster_2100"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.593"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          1347..1516
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="93.605"
                     /coverage="91.0"
                     /evalue="1.04e-65"
     Typing          complement(26132..26874)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 atttaaagtg ctataataaa cttaatataa caaaaacccc aactactggt aatagtcggg
       61 gtttggtaat aaaacgttta gaaactgttt atttatataa ttttcgatac ttgtattata
      121 taatgaataa tatcttagtg caagcaccta aatcattaaa taaatgtaaa gctaaataaa
      181 aacgttttat tacctcttac caaactaaaa tatggaaaga ggttttttgt catgcaaaat
      241 caatatttta cagtgcaaga aaattacaaa gaaagatttt atcaaatccc taaagtattc
      301 tttaccagtg aaaattataa aaatctaact aatgatatga aaatagccta tgctatctta
      361 cgtgatcgct taaatttatc tattaaaaat agctgggttg atgaagatgg taacatttac
      421 tttgtttatt caaatgaaaa gctaatggaa atcttaaatt gtaaaaaaga aaagttaaca
      481 aaaataaaaa aagggttaga aaacgatggt ctactcattc aaaaacgacg tggtttaaat
      541 aaaccaaata ttctatattt aatgaaacct attgtcacag aacgtgatat ttacaaaata
      601 gaaaaagaag aaaacgatgt tgaaccttac ggcgagaagg aagttcgaaa atcgaacgtc
      661 cagaagttcg aaaatcgaac gtccagaagt tcgaaaatcg aacgtccaga agttcgaaaa
      721 tcgaacacta atgatactga ctttaatgac attgacttta atgatactga gaataatgat
      781 atgaatgact tgaatgatat aaagtacaaa aatgaaatta gtaatcattc aaatcattca
      841 aatcaattta cacataattt tgatgataaa gaaatgctat tgcaagaatt cccagaacaa
      901 ctaactaatt atttattaaa atatgattat agagatttag aaatcataaa ggctgttatt
      961 cttaaagcaa aaaaatcatt taattcaagg catgaagata tgcattacat gttagaggac
     1021 attgaggatg aaatattaac ttctttaaaa agacttaaaa aagctataca tgatagggga
     1081 gttaaaggcc aaaaggaaac aatcaagtca atgcaagctt atttaatgca aacaattcta
     1141 actgaacttg aagaaacaca tgccctttat atgcgccgta aaaacatgaa acaatataat
     1201 atctttaatc aataattcaa atgattttat aacactcgaa gagacatcaa aatattccgt
     1261 taaatcatct gactttttaa ctgatgacga cgaaaaaaat caagaaattg taagtgattt
     1321 agaaaaaggt ttgtatcgaa aacgtatgtt aagttatggt ggattgctta aacaaaagca
     1381 taaaatttta aacttagacg atgccgaaga tggtaatttg attaatacaa gtgatgaaga
     1441 taaaacgaca gacgaagaaa aaaagcacat tcaattaccg caatttggaa tttcgaaaag
     1501 caaaattatt atttaagaca ttagtgataa ctgatgtctt tttttattgt ttttctgtaa
     1561 aaaagtgctg tcttattttt gtgacaaatg ctgtatgtag tgtcacaaaa gtgtgacact
     1621 acagctttgt atgatatcac tttaaaataa cttaaaaccc ttggaatgtc tggccttgcc
     1681 agatctatca tttttgaatg atagcaaatt tcccttatgc tcttacggag attttagagt
     1741 taaattaaaa tttctaagtt tttgataaga aaagccctgc aggaatttag aaaaacatgg
     1801 ggaagtttta aagtatttta tgctaatttt taaatttgca tgtaaatggg cagtatctaa
     1861 aaaattagtc actgattttg ctgaaatttt tgtttgtgaa attagcatat atttatttgg
     1921 ctcatatttg cgttttaaga gactgtatag atttttaagt acaaaaccta tatgatttgc
     1981 ctctaagtct tcaaaatgcc tcttaaaatc caaaataaaa gtgtttaata ttgtaataag
     2041 gattgctatt tttataaaag gagagatatc atgaagatta aaactttcgc tacttttact
     2101 catcgtcaat tagataaaca agttaatagg tttttaaaga atgatattca tgtattagaa
     2161 attcaaacac acagtaattg gttatatatt tcagctattg ttttttatga ggataaataa
     2221 ggaacatcgt atttatgccg aaaaaattta ttgatgttga gaagaaccct taactaaact
     2281 tgcagacgaa tgtcggcata gcgtgagcta ttaagccgac cattcgacaa gttttgggat
     2341 tgttaagggt tccgaggctc aacgtcaata aaacaattgg aataaaatca acctacagag
     2401 catccagctg caaatgcagt tccgcaaact gcttcacata caccgccggc tattggattt
     2461 acgattgccc atactccaca gtagtgagca catgcataaa gtccagccat actacaagcg
     2521 aatgctttgc cgttccattt gaatcctgca tatgttaccg gtctgttttt atcaactttt
     2581 tcagccttat attcaacgta atttttgtta ataagtattt ttccctcttt gttttcagtc
     2641 atacttcttt tttcggcaat gaattttgtg atttttttgt tgtagttatc atatattgtt
     2701 tcagaaacta caatttcttt tgttttttca tttttataag cgttattagc tatgtagcca
     2761 tatgcatttt tatcatttgc ttctgtagct agatatttta atttagaatt tttgtcttct
     2821 agctttattt ttttaaatcc ttcttttttc atttgctttt cgaatttttg catatcttca
     2881 tttttatttt gcaattgttc tagaaaactt atttctttct tggtcatttg tgatacttcg
     2941 atgtttttgc ttttcaattt ttctttttga ttttctagta aagaactttt ttgttcttca
     3001 tttgcgtaag cattagaaaa attcgcgcta aataccagta ggaacaagga aattattgaa
     3061 aataatttta taattttcat ttgatacctc caagataata agatatttta attgtataag
     3121 taagcgcttt ataaaatcaa tatttatttt aatatattta taaacatatt tttgaaagga
     3181 gtctatttta tgaatgaaaa tttagaaaaa tatataaaaa gtttgccact tttaggtttg
     3241 ttaattagta ttttgttaat tgttttattc ttttttattt tagatgttga tgaagattta
     3301 ttcgtggttt ttttatactg tttattgcct ttgatagtta atttgtctat ttatggtttt
     3361 tatgtttttg ttaaaagaaa gtaagattat gaataatttt gtttttaatt tgtatgcttt
     3421 gagggggttg gaaaacggta ggtgtataga ttagatttct tgtttttttg aaacgagtgt
     3481 gaacgagttt cttcttgtct tgatttttga taaaaacgcc ctacaggaat ttagaaaaac
     3541 gtggggaagt tttaaagaat tttatgctaa tttttaattt gcatgtaaat gggcagtgtc
     3601 taaaaatagt tattgttttt gctcaaattt ttgtttttga aaatagcata tatttatttg
     3661 gctcatattt gcgttttaaa agcatatata agttttagat ataaaactat atgaatcacc
     3721 cctaaatctt taaaatgccc tcttaaaatt caaaataagg gcataaaaaa taaaagctac
     3781 cccagataaa gtgaggtagc tttttctttc atacggtcta tttatttttc tttcgacgcc
     3841 gtatcgtcga tgtaattcaa aaaagttatg ggctataaat ctacatcact ttttcaagaa
     3901 tgtagtagca atattcaacg caaattaatt tttataactg ctcggaatat ctcaagccgt
     3961 ttctttaatt ttgaaataaa aaaatcgacg aaggtcgatt acgtttttgc acatgtcgat
     4021 ttatccgacg tataagtgcg cccttacggg atttaactag attataacga cgaattttag
     4081 acctgtaaag caataacaat taggtctacc aggtagataa agtgtacaaa gtagaaccga
     4141 aaaagttatt tattttgaag atttttcgta gatataattt gctaataaac ttcctaaaac
     4201 tgaataaaga aaaatagtta aactcatgta atcactccat aattctgaag tgtctccatg
     4261 tctacgcata gacacgcatt tatgccgaaa aaatttattg atgttgagaa gaacccttaa
     4321 ctaaacttgc agacgaatgt cggcatagcg tgagctatta agccgaccat tcgacaagtt
     4381 ttgggattgt taagggttcc gaggctcaac gtcaataaag caattggaat aaagcaccta
     4441 tgattattta aaaatataag ttataataca ttcaaaaata tttttgaatg aggtgtatta
     4501 tgattcaaac ggttgttgct gctgctgttc tttatattgc tacagcagtt gatttattag
     4561 taattttatt aatatttttt gctagagcaa agactagaaa agaatataga gatatttatg
     4621 ttggtcaata tttagggtct attattttaa tattagttag tttgttttta gcttttgtat
     4681 taaattatgt tccagaaaag tggatattag gtttattggg tttaatacca atttatcttg
     4741 gaattaaagt ggctatttat gatgattgtg aaggagaaaa gagagctaaa aaagaattga
     4801 atgaaaaagg attgtctaaa ttagttggta cggttgcaat tgttacgata gcaagttgtg
     4861 gcgccgataa tattggttta tttgttccgt attttgtgac attaagtgtt actaatttat
     4921 tacttactct gtttgtcttt ttaattttaa ttttcttctt ggtgtttact gcacaaaaat
     4981 tagctaatat tccaggaatt ggagaaattg ttgagaaatt tagtcgttgg attatggcta
     5041 ttatttatat agctttaggt ttatttatta ttattgaaaa tgacactatt caaacaattt
     5101 taggatttat attttaattt agggtgtgat tttatatgag ttatgaaaat acttgtgatg
     5161 tgatctgtgt acatgaggat aaagttaaca atgctttaag ttttttagaa gatgataaat
     5221 ctaagaaatt acttaacatt ttagaaaaaa tttgtgatga gaagaaattg aaaatcatat
     5281 tatctttgat taaagaagat gagttgtgtg tttgtgatat ttctttgata ttgaaaatga
     5341 gtgttgcttc aacttcacat catttaaggc ttttatataa aaatgaggta cttgattttt
     5401 ataaagatgg aaagatggca tattatttta ttaaagacga tgaaataaga gagtttttct
     5461 ctaaaaatca tgagggtttt tgaaacgagt ttcttcttgt cttgatacta taaaaaacaa
     5521 agttatataa cataagacga cttatcggaa gtagatatgc ttgtatattc acagatggta
     5581 taataataga gtcgcctatc tctcaggcgt caattgacga agagaggagg tgcattactt
     5641 tgctaatcat tttcgttcac atcatagcac cagtcatcag tggctgtgct gttgcgtatt
     5701 atacttattg gcttagtaaa cgcaacaaat aattaatagg cgactttata agccagcatc
     5761 gaaaaaatcc ccacactact gcaatagtgt ggggattggt gcattaattg ttaatcattt
     5821 tcgttatata aattataaca ctggttagta gagaaatgca aaatgattga attaatagta
     5881 aatgtattaa tgaatactca cacttatact tttaaaatag ttcttcctaa atgttgtcct
     5941 tttaaaagct gatctatcgt tttatagaat tcttcaaatc caatttcatt gtatagaagt
     6001 gaatttccta tattccattc atttgctaac ttactccata tatcttcacg gatattatga
     6061 tcaacatata cagaatcaat gccaattaat ttaatacctc taagaataaa cggtaatata
     6121 ttagcgttaa gtgaatttcc tgctacattt ccacatacag tagcaacacc ttgataattt
     6181 agacgtttta aaccgtataa tgttacatta ctccccactg tatctaagaa ataatcaaaa
     6241 ataccttttt taagcggttt attatcatct tcaattatta ttacttgttt tgcacctaat
     6301 ttttttgcga tttctatttg cttttctttt cttacgatag cagtgatatt ttcatatcca
     6361 attttatgta aaatttgtat agcaacactg cccacaccac ctgtagcccc agacactaaa
     6421 atttcaggtt gtgatttgat attcattcca tatttttcta gttcaaaaat tgataatgct
     6481 gccgtaaaac cggctgtgcc atataccata gactctttaa tagacatttc ttggggaata
     6541 ggaacaatcc actctccagg cacttgtgca tattctgaaa atccacctgt atgtgtcacg
     6601 ccaacatcat aaccagtaac taatacatta tcgccttctt taaacttatc attcgaactt
     6661 gattcaacaa tacctgcaaa atctatacca ggaatcatag gataatctct aattacaccg
     6721 cctttatatt gtaaagctag catatcctta taatttattg aagagtatac cacttttact
     6781 aatacatcac ccttcgataa atgagattca tcaacttttt ctactttata actaacattt
     6841 gatgcacttt ttctcactac taccgcattg aacatttatt agccttcttt cacaattgtt
     6901 ttgtagaagt atgtttttgt tgcaaaacta ttttcctaca aaacttatca tgatatgata
     6961 agcgagtcaa tactaatgat ttaagagagg ttttagttgt ggaattagat aattgtataa
     7021 attatttgtt gagtacttct cagaatagag tttttaaaca ttttaaaagt ttattaagtc
     7081 cctataatat tactccagca gaatatggtg ttttgaattg cttgattaat agtaatttga
     7141 atacacctaa agcgattggt aatactttaa atttagaacc ttcaacaata tctggaatat
     7201 tagataagat gtccaaaaag gatctaataa cacgtcaaac tgataatgaa aatagaagaa
     7261 ctgtgctaat aaacagtaca aataaagcaa aagacttatg gccaacatta gaaaagaaag
     7321 cctatcaact taataatcat tacttcgcta atttaactaa tgaagaaact gtagtgttta
     7381 aaaagatatt actaaagata aataaaacta cgttttaatt tttacgttat aaaaaagttg
     7441 aagtgcgaat tataatcgag taaatataaa tgatagctta gcttaattat atattaaagc
     7501 caactatact tttattcccg aaaaacctac tatccaaatt tctaagatac tttagcctct
     7561 ataataaaca tattgtaata taatttatgt attatttagg tttaccctaa tcgaacaata
     7621 aaaaatactt gtaaaatgct attgtcactt tgcttgatat atgagaatta tttaacctta
     7681 taaatgagaa aaaagcaacg cactttaaat aagatacgtt gctttttcga ttgatgaaca
     7741 cctataatta aactattcat ctattattta tgattttttg tatatacaat atttctagtt
     7801 tgttaaagag aattaagaaa ataaatctcg aaaataataa agggaaaatc agtttttgat
     7861 atcaaaatta tacatgtcaa cgataataca aaatataata caaactataa gatgttatca
     7921 gtatttatta tgcatttaga atattaaaat tccttcatta cactcttggc ggtttcactt
     7981 atcaacttat catttggctt atcactttta ttgtctttat tcgtaaaaat gactaaaaca
     8041 ataggttcag attggccctt aggataaaca aaagcaacat catttctaga agcatatgtt
     8101 attgcttgac cacttttatc agcaacctta tagtcttttg gaacaccatc tttaattaaa
     8161 gtgtctccgt ttttattatt aaacattaaa tcaagtaaga aatttttatt ttttttgctt
     8221 aattttccat ttgcgataag tttatttaaa gtcttgccga aagcagcagg cgttgaagta
     8281 tcttttttgc tctttggtga atagtaattt aattctatct catatctaac tggatttgtt
     8341 actttatctc ctagttcttt tagacgttgt ttaacttttt tgattccacc gatttctttt
     8401 ataattttat tgtttgctgt attatcacta tatgtcattg aagcctcaat aagttctttt
     8461 aaagtgatat cttttcctac atatttttct aaaataggag aataagcaac tatatcatct
     8521 ttgttaatat gtactttttt atttaactta ttataaggta cttgttctaa caaaatagca
     8581 ctatttatcg cttttgaagt cgaagcatag gcaaatctct tatctgaatt aaattttact
     8641 tccttaccac ttttagtatt taaagcataa acaccaatat gagcattata ttttttttct
     8701 aaatcattta actctttggc atgtgaactg tttgaattac atgcacttaa aactaaagca
     8761 attacaatta aaaatattaa ctttttcaaa ataaaccctc cgatattaca gttgtaattt
     8821 ttataaatca ataatattac aattgtaata ttgatgtcaa ttgtttatta taaatatttg
     8881 aaagaaggtg tcaaaatggc taaattacta ataatgagcg tagtaagctt ttgttttata
     8941 tttctattgt tagtattttt taggtacata ttaaaacgct attttaatta tagtttaaat
     9001 tataaagttt ggtatctaac tatgcttgct ggattaattc cttttatccc aattaaattc
     9061 tcttttataa aatttaataa tgtgaataat caagcgccca cagttgaaag taagtcacac
     9121 gatttgaacc ataacataaa taccaccaaa cctattcaag agttcacaac agatatccat
     9181 aagtttaatt gggattcaat tgataatatc tgcacagtta tttggatagt tttagttatt
     9241 attttaagtt ttaaattttt gaaagcctta ttatatctta aatatttaaa gaaacagtca
     9301 ctttatctaa acgaaaatga aaaaaataaa atagatacga tacttttcaa ccatcaatat
     9361 aaaaaaaata ttgtgattcg aaaagcagag gctattcaat ctccaataac tttttggtat
     9421 gggaaatata ttattttgat tcctagttca tattttaaaa gtgtaattga taaaagacta
     9481 aaatatataa tactgcatga atatgctcat gctaaaaata gagatacttt acatttaatt
     9541 atctttaata tcttctctat tattatgagt tacaatccat tagtacatat tgtaaaaaga
     9601 aagataattc atgacaatga agtagaagcc gatagatttg tccttaataa tattaacaaa
     9661 aatgaattta aaacttatgc ggaatctatt atggactccg tattaaaaac cccattttcc
     9721 aacaaaaata tattaagcca ttcatttaat ggtaaaaaat cattactcaa aagtagatta
     9781 attaatataa aagaagccga tctgaaaaag cagtcaaaat taattctaat ttttatttgt
     9841 atttttactt tttttatcat gataattcaa agccagtttt taatggggca atccttaact
     9901 gattataatt ataaaaagcc cttacaaagc gattaccaaa ttttagatga aagtaaaaat
     9961 tttggttcaa atagtggatc tttcgttatg tacagcatga agaaagacaa atactatatt
    10021 tataatgaaa aagaaagtag aaaaagatat tctcctgatt caacttacaa aatttattta
    10081 gcactgtttg gacttgaccg tcatattata agtgataaaa attcacgtat gtcatggaat
    10141 cataaacatt atcttttcga gtcttggaat aaggaacaag atttaaatac agcaatgcaa
    10201 aattcagtta attggtactt cgaacgtatt agtaatcaaa taccaaagaa ctatactgcg
    10261 gctcaactca agcaattaaa ttatggtaat gaaaatttgg gaagttataa aagctattgg
    10321 atggaagata gtttgaaaat atctaatctt gaacaagtaa tagtttttaa aaatatgatg
    10381 gaacaaaata accattttag taaaaaagca aagaatcaat tatcttcttc attattgatt
    10441 aagaaaaatg aaaagtatga actgtatggg aaaacaggta caggtatagt aaacgggaag
    10501 tataataatg ggtggtttgt aggttacgta attacaaatc atgataagta ttattttgct
    10561 acacatttat cagatggaaa cccgtctggg aaaaatgctg aattaataag tgaaaaaata
    10621 ttaaaaggaa tgggtgtttt aaatgaccaa taagcaagtt gaaatatcta tggctgaatg
    10681 ggatgttatg aatataatat gggataaaaa atcagtatca gctaatgaaa ttgtagttga
    10741 aattcaaaaa tataaagaag ttagtgataa aacgattaga acattaatca caagactata
    10801 taaaaaagag attataaaac gatacaaatc agaaaatatt tatttttact catcaaatat
    10861 taaagaagac gatattaaaa tgaaaactgc taaaaccttt cttaataaac tgtatggagg
    10921 ggatatgaaa agtttagtgc tgaattttgc gaaaaatgaa gaattaaata acaaagaaat
    10981 tgaagaattg cgagacattt taaatgatat tagtaaaaag taattagagg tatgtttcaa
    11041 acataataca tatgtaaacc atacttgact cttattaaat tagttttgtt aatgacattt
    11101 aaaatatatt attaaagatg agagtgtcca gaaaataacc attttctgta cactcttgtt
    11161 ttttgtctaa ataagtaagt attacataga attatgtgtt caaaaaccca acaaaaaatc
    11221 tatgttcaca aaagacctcg taatcaagtt atggtacact aaaggtgtat ataggaggtc
    11281 tgtattttga aaataggtta tgcaagagtt tcaactggat tacaaaattt gaatttacag
    11341 gaggatcgat taaatacata tggttgtgaa aagatattta atgaccatat gagtggttca
    11401 aaaagtaagc gacctggttt agataaagca attgaatttg cgaggtcagg agatacgatt
    11461 gttgtttgga gattagatag actaggacgg aacatggagg atttaatcac gttagttaat
    11521 gaacttaacg aacgaggtgt gagttttcat agtttagaag aaaatataac gatggataaa
    11581 tcaagttcta caggacaatt attatttcat ttattcgcag catttgcaga gtttgaacgt
    11641 aatttaattt tagagcgatc atcagccggt cgaattgcag cacgtgctag aggccgatat
    11701 ggaggtagac ctgaaaaatt aaataaacaa gatttaaact tacttaagac actttatgat
    11761 aatggtacgc caattaaaac aattgcagag cagtggcaag tttcacgtac aactatttat
    11821 cgttatctca ataaattaga ggcaaaagag aataaaaaca agtagagcaa ctaatctagc
    11881 ttactataat gaatctacta aataatttta tatatcatta acatacaaag actttgattc
    11941 aatgtcactc gatgtaaaag agacgttctg acagcgtcta aaatctcata atattttcct
    12001 gttatgagat tttaataata acacaagaaa aaagcgtaca aattcgtacg cttttttaat
    12061 ataatacctg tttcactaat gaacgtttta agtatcttca tcattaactg aaactacagt
    12121 aataatactc gtcaacaata ttagtatagt taaaatagaa agacttagga ctggcataac
    12181 cgaactaaaa ttatatttga aatataaaag tgctaatgaa gagagaaatg taaaaataat
    12241 aaataccaaa gaccattttt ctaatttatt cattggcttc acctctttga acttttatat
    12301 aatcatagga gatattttta ctacgattta taaaaaataa gaagataatc attattaaag
    12361 aaacgattaa tataatgttg aatcctatag tatcacctaa ttcgtttaca cctttgccta
    12421 atatcggaga tacaaagctt tgtattaata atgaaagaga tgcccatata gtaaatgagg
    12481 ttctgttgca aagttgaatt tatagtataa ttttaacaaa aaggagtctt ctgtatgaac
    12541 tatttcagat ataaacaatt taacaaggat gttatcactg tagctgttgg ctactatcta
    12601 agatatgcat tgagttatcg tgatatatct gaaatattaa gggaacgtgg tgtaaacgtt
    12661 catcattcaa cggtctaccg ttgggttcaa gaatatgccc caattttata tcaaatttgg
    12721 aagaaaaagc ataaaaaagc ttattacaaa tggcgtattg atgagacgta catcaaaata
    12781 aaaggaaaat ggagctattt atatcgtgcc attgatgcag agggacatac attagatatt
    12841 tggttgcgta agcaacgaga taatcattca gcatatgcgt ttatcaaacg tctcattaaa
    12901 caatttggta aacctcaaaa ggtaattaca gatcaggcac cttcaacgaa ggtagcaatg
    12961 gttaaagtaa ttaaagcttt taaacttaaa cctgactgcc attgtacatc gaaatatctg
    13021 aataacctca ttgagcaaga tcaccgtcat attaaagtaa gaaagacaag gtatcaaagt
    13081 atcaatacag caaagaatac tttaaaaggt attgagtgta tttacgctct atataaaaag
    13141 aaccgcaggt ctcttcagat ctacggattt tcgccatgcc acgaaattag catcatgcta
    13201 gcaagttaag cgaacactga catgataaat tagtggttag ctatattttt ttactttgca
    13261 acagaaccag catttgtttt aatatttgtt ccaaagagcc atcatggctt tgacagagct
    13321 cttcttctat gcaaatgctt ttaatccgat ccacacgaaa attcctatat tcatttctta
    13381 gcctgcaaaa ccgattaagt accagttctg ttcataaaac cccagtgata taggctctat
    13441 cattctgctt tccggttctt gccctcctga tgcaggatat tgaattgata ttaccctttt
    13501 attgcagatt gcagtctgaa ttgctgcaat aacgttatcc gccaatgtat ttttctgtcc
    13561 agatgtgctg tacacgttaa tactgttctc caactcctgt gcatagtttt tttcaccatg
    13621 cttcaaaata gatttgattt tatacatagc tgaatcaaaa tcctttataa atgattcatc
    13681 tccatggcaa tttaaaaatt tccctgctgt aatcaatgca cccacttccg ccgctgtaaa
    13741 cattaccggc agaagtagga agccctctac aagaaaatat ccttttccgg cctcagatcc
    13801 aattggtatt ccggcttctt caagtgtccg gatatctctg taaactgtcc ttaagcttat
    13861 attaaatcgc tgtgcaattt ctttggcagg aattattttt ttgattgcag ctgaataaga
    13921 atagaggtta ctctgttaat cctgttcaaa ttttattcct cctctgtgac ttccataaaa
    13981 agtatatcct atgcgttctt aagctagctg ctgttagtgc ttctcattgc accctggtta
    14041 taaaagccat actcacaaac ctcttcacca aaactcttta catctctaat atagaactct
    14101 atctagcgaa cttttagaaa agatataaaa catcagagta tggacagttg cggatgtact
    14161 tcagaaaaga ttagatgtct aaaaagcttg tagttaaagc tttttagaca tctaaatcta
    14221 ggtactaaaa caattcatcc agtaaaatat aatattttat tttctcccaa tcaggcttga
    14281 tccccagtaa gtcaaaaaat agctcgacat actgttcttc cccgatatcc tccctgatcg
    14341 accggacgca gaaggcaatg tcataccact tgtccgccct gccgcttctc ccaagatcaa
    14401 taaagccact tactttgcca tctttcacaa agatgttgct gtctcccagg tcgccgtggg
    14461 aaaagacaag ttcctcttcg ggcttttccg tctttaaaaa atcatacagc tcgcgcggat
    14521 ctttaaatgg agtgtcttct tcccagtttt cgcaatccac atcggccaga tcgttattca
    14581 gtaagtaatc caattcggct aagcggctgt ctaagctatt cgtataggga caatccgata
    14641 tgtcgatgga gtgaaagagc ctgatgcact ccgcatacag ctcgataatc ttttcagggc
    14701 tttgttcatc ttcatactct tccgagcaaa ggacgccatc ggcctcactc atgagcagat
    14761 tgctccagcc atcatgccgt tcaaagtgca ggacctttgg aacaggcagc tttccttcca
    14821 gccatagcat catgtccttt tcccgttcca catcataggt ggtcccttta taccggctgt
    14881 ccgtcatttt taaatatagg ttttcatttt ctcccaccag cttatatacc ttagcaggag
    14941 acattccttc cgtatctttt acgcagcggt atttttcgat cagttttttc aattccggtg
    15001 atattctcat tttagccatt tattatttcc ttcctctttt ctacagtatt taaagatacc
    15061 ccaagaagct aattataaca agacgaactc caattcactg ttccttgcat tctaaaacct
    15121 taaataccag aaaacagctt tttcaaagtt ggcgtataac atagtatcga cggagccgat
    15181 tttgaaacca caattatgat agaatttaca agctataagg ttattgtcct gggtttcaag
    15241 cattagtcca tgcaagtttt tatgctttgc ccattctata gatatattga taagcgcgct
    15301 gcctatgcct tgccccctga aatccttaca tacggcgata tcttctatat aagcgtaccg
    15361 gttccaattt tttcgcagtt taacttttcc gacgcattta tcgtcttggt agtaaagata
    15421 tattatctta tcagtattgt caatatattc aaggcaatct gcctcctcat cctcttcatc
    15481 ctcttcgtct tggtagcttt ttaaatatgg cgcttcatag agtaattctg taaaggtcca
    15541 attctcgttt tcatacctcg gtataatctt acctatcacc tcaaatggtt cgctgggttt
    15601 atcgatatct ttcaggtgcc ctgctttcat ttctgtaatc actgttcccg cctctcttct
    15661 atatcagcgg catatgtgct atccaggcag ccggttttac cagtgtattt tttatacatg
    15721 tccctggtat attttgttat attcctatca tactccggat aggcataatg aagcctttcc
    15781 gccacctcac cggataccgc cctgaacaat tgatggcata gaaataatgc ttcccatatg
    15841 ttttcatagg aatccatccg gtaggtggac aaaagtttct cccacaaatc ctcggatata
    15901 tacctttcaa taaacttata gttcttgcct acacttcatt taaagcctgt ttcgatgccg
    15961 accttccatg atatcattct cagcagctca tggcgaacaa tctgattaaa atgatcaata
    16021 gcaaataaaa tttccttacg gcacaatcct ttaataacat aaggtgttac attccaaaat
    16081 tcattgcagc aatcatcata ctcccttgcg cttggctttc ttacatgata atctatatca
    16141 gtcggaacta tgtccctttt aattctacaa tctttatcaa ttagaacctt tattaattta
    16201 tcgcccttta ggtaattatc taactcttcc aagggcaata aggtaagatc aattttattg
    16261 taatcatcaa atagctataa tagatttaga ggtaaagaaa ttaaatacat tgaagagcag
    16321 aaagatttta caaaagagta ttttaataaa aatgatggtt ctgttgcaaa gtaaaaaata
    16381 tagctaatca ctaatatatc atgtcagtgt tcgtttaact tgctagcatg atgctaattt
    16441 cgtggcatgg cgaaaatccg tagatctgaa gagacctgcg gttcttttta tatagagcgt
    16501 aaatacactc aatacctttt aaagtattct ttgctgtatt gatactttga taccttgtct
    16561 ttcttacttt aatatgacgg tgatcttgct caatgaggtt attcagatat ttcgatgtac
    16621 aatggcagtc aggtttaagt ttaaaagctt taattacttt aaccattgct accttcgttg
    16681 aaggtgcctg atctgtaatt accttttgag gtttaccaaa ttgtttaatg agacgtttga
    16741 taaacgcata tgctgaatga ttatctcgtt gcttacgcaa ccaaatatct aatgtatgtc
    16801 cctctgtatc aatggcacga tataaatagc tccattttcc ttttattttg atatacgtct
    16861 catcaatacg ccatttgtaa taagcttttt tatgcttttt cttccaaatt tgatataaaa
    16921 ttggggcata ttcttgaacc caacggtaga tcgttgaatg atgaacgttt acaccacgtt
    16981 ctcttaatat ttcagatata tcacgatagc tcaatgcata tcttagatag tagccaacgg
    17041 ctacagtgat aacatccttg ttaaattgtt tatatctgaa atagttcata cagaagactc
    17101 ctttttgtta aaattatatt ataaattcaa ctttgcaaca gaacctccta actgtattac
    17161 caccttaaaa gtagttgcag acgcacttcc taaatcgtca gcagtgttta accacatatc
    17221 atcaacaata atcatatgac ctgttgatga tactggagca aattctgtca acccttcaac
    17281 tacacctaaa ataaatgctt taatctgctc tataaaaccc atttttctcc tccttttaac
    17341 ttatatcagt ttttttaaag tatgagaata atataattac actgaatata gatgtaacaa
    17401 ttatgataat taaagataat agaaatggat aagtattagg taatgttcct ctagatatgt
    17461 ctccaactgc agcccaagga aataatcctc tatgttcaga attagcagtc attaaattta
    17521 tcaaagtaat tattatggtt aaaacaattg tgggaacata atttttaaaa tatatcgaca
    17581 aaataattat tggtggagat aatatccata ataacactcc gccaataaca aatgtaaaga
    17641 atgaatcaat tattaaactc tggcttaacc cttgaaaatg caatagcata cctagcatta
    17701 aagttagcaa ccatgcaata acagatagtg tttgaatcca caagaataat aatattattt
    17761 tacttactaa aaaactttct ctagatatag gtataattaa taagtttttt aaagtatctt
    17821 ctatatattc tcttccaaac aaataggcta ttataacccc atatagagga ggtccaataa
    17881 ttagcatatg atataaactg acttcttcaa ataactgttt aaatacaata ttaggagtcg
    17941 gtactttcgt ccgcatacta ataaaagaag ctacaaccac cataaaaggt gctacgcatg
    18001 tacctaaaat acttattaga aacatatatg atctttttaa cttaataaat tctgtacgga
    18061 gtagattatc caattgtgcc acctcctact aagtcttcga aataagtttc tagattatct
    18121 tctatcactc tcatctggaa aacatcaata ttgtttaata ctaataatct attaatttct
    18181 tgttgtctat caatatgtga ataaatttta aattcgccat tttctttaat tttatagtca
    18241 taaattccga agttagtttc caacaaacat gcaacttttt cttcatctga tactgatata
    18301 cttataaatt gtctgttctt tttttttaaa tcttcataca taatttcttc taacaaaact
    18361 ccgttatgaa taatacccac cttgtctact aactgctcta tttctgacaa tatatgactt
    18421 gaaattaaaa tggttatatt tctagattga gccagatcct taatcaactt tctaatttct
    18481 tttatgccaa taggatctaa tccattcgtc ggctcatcaa gtatcaataa ttcgggattg
    18541 tgcaataaag ctctcgcaat ccctaaacgt tgcttcatac ctaaagaata atttttaaac
    18601 aattttactt tttcagaagc tagtcctact atttctaaca cttcttcaat tgcattttct
    18661 ttttgtatac ctaatatttt agcatttata gttaagttct ctttagctgt caaattacta
    18721 taaaaacctg gcgtttcaac catagcacca atatttttta aaatttcagt tttattactt
    18781 tcgaactctt tttcaaatat tttaatatta cctttcgtag gtttaattaa gcctaaaagc
    18841 attcttatag tagttgtttt gcctgcacca tttcttccta aaaaaccata aatttgtcca
    18901 ctttcaacag ttatactcaa attattaact gctatctgac ttccatattg ctttgttaag
    18961 ttatttattt caattatatt attcaaattt ttcacctctg gcacctttct tagtttgttg
    19021 ttacctttat cttacgcgcg attagaaaag gctgccttta tctattctta caaaaacagc
    19081 cgctaatctt acaaaaatga aagattggag ttatttaaat tgaatggtga atattgaacc
    19141 atcgtttaat gtagatgtag cacttacttt atggcctaag cgctttgaga ttgtgctgac
    19201 aatatataaa ccaataccgc ttgatttctc acttattcta ccgttatagc ccgagaaacc
    19261 tttatcaaag attttcggta aatcactcgc attaatgccg ataccgttat ctcggattga
    19321 taatttcttt gtattttcgt caaacgtaat ccacacatct ttgccacgtg catattttaa
    19381 tgcattgttt aatatttgct caatcataat tgatgcccat ttggcatctg ttaatataac
    19441 cgcttcactt ttctcataat gcaactttgt ttgatgatga ataaactgta tcgcataacg
    19501 tttaatcagt ggtcgaatta attcatctac actcacttcc ataaagacca tgtatgtctt
    19561 ttggttcatg agtttcaaat agttcagtgc aagattcgtg taattatcaa tttgtaagac
    19621 ttcattacgc acgttagaaa tcacgtgttc atcaggatct tcaagcagta actttgatgc
    19681 tgtaatcggt gtcttgattt gatgcaccca cattaaaaaa tatgactcta actcactttg
    19741 gtagttaata aagtcattac gaagtttatg gttttcgatt cttaaatctt cgttctgttc
    19801 ctgtagtgtt tattcttttt taaagttcat gtaatggata ccccagtaaa tcattgaaac
    19861 aaacaataca atacctagac caatcatata tgcttgcatc ggcacattat acatgaataa
    19921 tataaagtag aataaagcac aagtaaggat gacaatataa atttcacgtt ggattgattt
    19981 caagaaattc atacgtcacc tacacgatat ccgacatttt tcttcgtttc gataaaatct
    20041 gtaagtccta gtttttgtag ctttttgcgt aaacgtgtaa tgttgacagc aagcgtattg
    20101 tcatcaatga agtgttctga ttcccagcat ttttcgatta acgcattacg actgacgaat
    20161 ttgcccttgt tctggaataa gctatgcatg atttgcaatt cagtgtgtgt caggtctatg
    20221 gtttcttcat taaatttaag ctttgctgca tcaagtagta actcgcaatc atctactgtt
    20281 aaattattaa cttgagtggt gaaatcatac gtgcggcgta atagtgcttg aatcttagta
    20341 attgtaacag tcatattaaa tggctggttc tgttgcaaag taaaaaatat agctaatcac
    20401 taatatatca tgtcagtgtt cgtttaactt gctagcatga tgctaatttc gtggcatggg
    20461 gaaaatccgt agatctgaag agacctacgg ttctttttat atagagcgta aatacattca
    20521 atacctttta aagtattctt tgccgtattg atactttgat atcttgtctt tcttacttta
    20581 atatgacggt gatcttgctc aatgaggtta ttcagatatt tcgatgtaca atgacagtca
    20641 ggtttaagtt taaaagcttt aattatttta gccattgctg ccttcgttga aggtgcctga
    20701 tctgtaacta ccttttgagg cttaccaaat tgtttaatga gacgtttgat aaacgcatat
    20761 gctgaatgat tatctcgttg cttacgcaac caaatatcta atgtatgtcc ctctgtatca
    20821 atggcacgat ataaatagct ccattttcct tttattttga tatacgtctc atcaatacgc
    20881 catttgtaat aagctttttt atgctttttc ttccaaattt gatataaaat tggggcatat
    20941 tcttgaaccc aacggtagat cgttgaatga tgaacgttta caccacgttc tcttaatatt
    21001 tcagatatat cacgatagct caatgcatat cttagatagt agccaacggc tacagtgata
    21061 acatccttgt taaattgttt atatctgaaa tagttcatac agaagactcc tttttgttaa
    21121 aattatatta taaattcaac tttgcaacag aaccgtattt tatgagtaca ctctaaatta
    21181 aggagatgta taatcaatct aaaattgtat ttttatactt ttgttatata atctttctac
    21241 ttagagatat attgtaaaaa aaccaacaaa atgttatatt aacattacta ttttatcgat
    21301 gaaggaggat taaaatgaca gcttctatga gactcaaata aacctttttg aatacaaaac
    21361 taaattaatt caaaaaggct tgtccgcaat acacactcat aggatgactt atgtcatttt
    21421 ttatccttcg ataggaataa taaacgcttt caaatactaa aacatcataa taaattttta
    21481 agtgtttgaa agtgtaatgt gaatgagacg ggagtagcct gtctcatttt tttgcgtaca
    21541 cgtcctttaa atatacaagg agtgtataaa tatggaacaa tatacaatta aatttaacca
    21601 aatcaatcat aaattgacag atttacgatc acttaacatc ggtcatcttt acgcttacca
    21661 atttgaaaaa atagcactta ttgggggtaa tggtactggc aaaaccacat tactaaatat
    21721 gattgctcaa aaaacaaaac cagaatctgg aacagttgaa acggttggcg aaattcaata
    21781 ttttgaacag cttaacatgg atgtggaaaa tgattttaac acgttagacg gtagtttaat
    21841 gagtgaactc catataccta tgcatacaac cgacagtatg agtggtggtg aaaaagcaaa
    21901 atataaatta gctaatgtca tatcaaatta tagtccgata ttacttttag atgaacctac
    21961 aaatcacttg gataaaattg gtaaagatta tctgaaaaat attttaaaat attactatgg
    22021 tactttaatt atagtaagtc atgatagagc acttatagac caaattgctg acacaatttg
    22081 ggatatacaa gaagatggca caataagagt gtttaaaggt aattacacac agtatcaaaa
    22141 tcaatatgaa caagaacagt tagaacaaca acgtcaatat gaacagtata taagtgaaaa
    22201 acaaagattg tcccaagcca gtaaagctaa acgaaatcaa gcgcaacaaa tggcacaagc
    22261 atcatcaaaa caaaaaaaca aaagtatagc accagatcgt ttaagtgcat caaaacaaaa
    22321 aggcacggtt gagaaggctg ctcaaaaaca agctaagcat attgaaaaaa gaatggaaca
    22381 tttggaagaa gttgaaaaac cacaaagtta tcatgaattc aatttcccac aaaataaaat
    22441 ttatgatatc cataataatt atccaatcat tgcacaaaat ctaacattgg ttaaaggaag
    22501 tcaaaaactg ctaacacaag tacgattcca aataccatat ggcaaaaata tagcgctcgt
    22561 aggtgcaaat ggtgtaggta agacaacttt acttgaagct atttaccacc aaatagaggg
    22621 aattgattgt tctcctaaag tgcaaatggc atactatcgt caacttgctt atgaagacat
    22681 gcgtgacgtt tcattattgc aatatttaat ggatgaaacg gattcatcag aatcattcag
    22741 tagagctatt ttaaataact tgggtttaaa tgaagcactt gatcgttctt gtaatgtttt
    22801 gagtggtggg gaaagaacga aattatcgtt agcagtatta ttttcaacga aagcgaatat
    22861 gttaattttg gatgaaccaa ctaatttttt agatattaaa acattagaag cattagaaat
    22921 gtttatgaat aaatatcctg gaatcatttt gtttacatca catgatacaa ggtttgttaa
    22981 acatgtatca gataaaaaat gggaattaac aggacaatct cttcatgata taacttaaaa
    23041 actatacact aatttatatt gaatattagg ttcatttata tcaatataaa aaatacgttc
    23101 acaagaaaaa tataatagaa ataaggatcc aataaaatga ctcgacataa tgaaattatt
    23161 aaatgtgcag aaaaatatca attacacatc caacctcaaa caatctcatt gaatgaatcg
    23221 ggacttgatt ttcaagttgc atttggaaaa gataaacatg gagtagaatg ggttttgaga
    23281 ctaccaagaa gacctgacgt ttataaacga acaaaacccg aaaaacaaac ggtagacttc
    23341 ttacagaaga atgtttcatt tgaaataccg aagtggaaag tacatgcaaa agaccttatt
    23401 gcttacccaa aacttacagg taaacccgca gccacaatag atccagaaat acaaaattat
    23461 gtatgggaaa ttgaacacaa accattacca gaaaacttta ttaacacatt agctgaaaca
    23521 ctcgtagatt tacacaacat accagaagaa aacattaacg ttcagcatat aaatatcaaa
    23581 accatacaag aaataaaaaa tgactttcaa agaagaatga ataaagttaa agaaacttat
    23641 ggcgtatcag atgaattatg gaacagatgg aaacaatggt tagaaaacga cgaactatgg
    23701 cctcgacatg cgaccatgat acatggggac ttacatccag gacatataat ggtagataac
    23761 caagcaaacg tcacaggtct catagactgg actgaagcaa cccactccga cccatcaatg
    23821 gactttatag gacaccatcg tgtattcgac gacgaaggat tagagcaact tataacagca
    23881 tacggtaaag ctggaggtga aatatggcca cgaatgaaag agcatataat agaactcaat
    23941 gcagtattcc caatgtttat cgctgagttt gctatggaat caggagaatc ggcgtatgaa
    24001 acgatggcat tgaaagagtt aggtatgaaa gagtagaact tatattaaaa gaggcccatt
    24061 ttaaagacga aggcaatcct gatgaaattt taaaactgcg tttaattagt gatggtcttt
    24121 ggttttctat aatgtattaa atatctggac atggaacaaa tgcaacaaat ggaaagaatc
    24181 gttttcgaaa tttctaactc cttaaatcag gaggataaat aaacggtcat tttcattgaa
    24241 agcacttata taaatttcat caattttaat acctaccgta aatacatttc ataagtatta
    24301 aacagatgat taaaattttt agttaattta aatatttatg atagagatga ccttcaaatg
    24361 aacggttctg ttacaaagaa aaaatctata tttattttta gtaagtttta attatagata
    24421 tgtacacttt gagtacaccc taaccataca aaaagaattg ttgaaattat aacaattaaa
    24481 acgtatgatt agggtgtata tttattatgg agtgaagatg aatgattata ggttatgcga
    24541 gagtatcatc gatagatcaa aatttagaaa gacaattgga taatttaaag acgtttggtg
    24601 tggagaaaat ctttacagag aaacagtcgg gaaagtcagt ggaaaataga cctgtatttc
    24661 aagaagcact caattttgtc agaatgggag atcgattcgt tgtggaatct attgatcgtt
    24721 taggacgtaa ctatgatgaa attattgaaa ctgtgaatta tttaaaagaa aaagacgttc
    24781 agttaatgat taccagctta cctatgatga atgaagtaat tggcaatcca ttactggata
    24841 agtttatgaa agatttaatc attcaaatat tagcaatggt ttcagaacaa gagagaaatg
    24901 aaagtaaacg tcgacaagcg caagggattc aagttgcgaa ggaaaaaggc gtatataaag
    24961 ggcgcccttt actttattca ccaaatgcta aagacccaca gaaacgtgtt atttatcatc
    25021 gcgtggtgga aatgttagaa gaaggcaaag cgattagtaa gattgcgaaa gaagttaata
    25081 tcacaagaca aacagtttat agaattaaac atgataaggg attatcttga taaattgatt
    25141 gtcaatgcaa atgagcgtct ctcacagtgt ctcaaattcc ataacatatt attgaattga
    25201 gattttaata attatacaag aaaaaagagt acgagttcgc agctttctat atagtaattg
    25261 ttttactaat aaggtgtttt aaaatatatt ataatgtaaa aagtatttga catttgtatc
    25321 aaaaatattt acactcataa atgtcaaata ctttttacat ttatgaggtg ttataatgaa
    25381 tttaattcct tttattatta ttttaatttt ttcttgttta tggacggcta taactaacaa
    25441 atatttacct tcagaaacat tagataaaaa aggacaacaa gatcgatacg atgaaagaca
    25501 acgtaaaatg tttattgaaa tactggctaa aagttttatt tggattgtat attgtatgtt
    25561 atttacacta gtgcttaaat ttacaggttt gtcaccaagt attgaaggat cttggttttc
    25621 tcaatatcca gaaattttct ttataattgt agcactattt cttatgctgt ttaattacta
    25681 tactacaaat aaaaaatata catctaaagg ttaaattaat gaaaaataga attagagaat
    25741 atagaaaaca aaaaggaatt tctcaagaaa ctttaagtaa agaattaaaa gtgtctaggc
    25801 aaactattaa tgcaatagaa aacaataaat atgatcctac attgacatta gcatttaagt
    25861 tggcaagatt gtttgataca actgtggatg aattattttc ttaaccattc atttatcaca
    25921 aaaagagagt gcgaattcgc actctctttt tgtgtagtag tactattaaa ttttgtctca
    25981 ataacgaacg tttataacgc aatcatgatg agagtattaa tacagttaat tatttgaaat
    26041 actttagttt acataatcga tgattaccag aagttctcac tatataaaag acactaaaat
    26101 tttataactt ttagtgccta atcaattatt ttagctacca aacaaacgac tccaaaaccc
    26161 ctttttaggt tccgtttctt cactcttttc ttctatatca ctatcattgt catttagatt
    26221 agctggaacg tcttcttttt ttgcttcttc accttgtgta ctttcgtcgc tttgacttcc
    26281 agatatatcc ttatattgaa tctctgtttc tttagtttct tcctgatctc tgttaatatt
    26341 tacaggatta gtagtatatg ttttttcttg tgcatcaacg ttttgtctag tgttagtaga
    26401 tgtatcaaag ggataattaa ggtgtttttc tttttctaat tgattttcta atttttgaat
    26461 ctttttatta ctctctaatg ccagaacttg ctgattttca agcaattttg atctttcttg
    26521 caactctttt ctgtaaaatt caattgttgt ttcatgacga ctttcttgtt tttcaatttg
    26581 attatttaaa gtatcaatct gatttttaag gatttctact atttgagcat cgcttttcga
    26641 ttcaaaatta atattatccg accctttttt ttgtttgtct tcagtagtac tttcaaaacc
    26701 atatttcttt ttattttcat ttactctttg aatgattttt tctatatcgg tatcttcttt
    26761 aataaacgaa gtgttttcct gttttattgt ctctatattc aatcgcttaa tattattaaa
    26821 aatcgtttgc ttactaaccc ctaattcttc actcaacttt ttcacacttt tcatatcatc
    26881 aaccctttat aaaatgttta taaacccttg ataaaatatt ataagcttat aatgcttaat
    26941 aataaagtga ttaataaata aaaataaaca tccatcaacc tttttatcaa gggtttatga
    27001 aaggtttatg atatttatca agggtttata aacccttgat aaagctatat tttccctttt
    27061 ataagttt
//
