LOCUS       NZ_CP002149            27068 bp    DNA     circular CON 03-MAY-2024
DEFINITION  Staphylococcus aureus strain LAC plasmid pLAC-P03, complete
            sequence.
ACCESSION   NZ_CP002149
VERSION     NZ_CP002149.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN14224446
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 27068)
  AUTHORS   Kennedy,A.D., Porcella,S.F., Martens,C., Whitney,A.R.,
            Braughton,K.R., Chen,L., Craig,C.T., Tenover,F.C., Kreiswirth,B.N.,
            Musser,J.M. and DeLeo,F.R.
  TITLE     Complete nucleotide sequence analysis of plasmids in strains of
            Staphylococcus aureus clone USA300 reveals a high level of identity
            among isolates with closely related core genome sequences
  JOURNAL   J Clin Microbiol 48 (12), 4504-4511 (2010)
   PUBMED   20943864
REFERENCE   2  (bases 1 to 27068)
  AUTHORS   Kennedy,A.D., Porcella,S.F., Martens,C., Whitney,A.R.,
            Braughton,K.R., Chen,L., Craig,C.T., Tenover,F.C., Kreiswirth,B.N.,
            Musser,J.M. and DeLeo,F.R.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-AUG-2010) Laboratory of Human Bacterial Pathogenesis,
            Rocky Mountain Laboratories/NIAID/NIH, 903 S. 4th Street, Hamilton,
            MT 59480, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_009948145.1-RS_2024_05_03
            Annotation Date                   :: 05/03/2024 03:46:09
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 32
            CDSs (total)                      :: 32
            Genes (coding)                    :: 26
            CDSs (with protein)               :: 26
            Genes (RNA)                       :: 0
            tRNAs                             :: 0
            ncRNAs                            :: 0
            Pseudo Genes (total)              :: 6
            CDSs (without protein)            :: 6
            Pseudo Genes (ambiguous residues) :: 0 of 6
            Pseudo Genes (frameshifted)       :: 2 of 6
            Pseudo Genes (incomplete)         :: 4 of 6
            Pseudo Genes (internal stop)      :: 2 of 6
            Pseudo Genes (multiple problems)  :: 2 of 6
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP002149.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..27068
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="LAC"
                     /db_xref="taxon:1280"
                     /plasmid="pLAC-P03"
     gene            1..984
                     /locus_tag="HS259_RS00005"
                     /old_locus_tag="SUP_0001"
     CDS             1..984
                     /locus_tag="HS259_RS00005"
                     /old_locus_tag="SUP_0001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_001181107.1"
                     /translation="MQNQYFTVQENYKERFYQIPKVFFTSENYKNLTNDMKIAYAILRD
                     RLNLSIKNSWVDEDGNIYFVYSNEKLMEILNCKKEKLTKIKKGLENDGLLIQKRRGLNK
                     PNILYLMKPIVTERDIYKIEKEENDVEPYGEKEVRKSNVQKFENRTSRSSKIERPEVRK
                     SNTNDTDFNDIDFNDTENNDMNDLNDIKYKNEISNHSNHSNQFTHNFDDKEMLLQEFPE
                     QLTNYLLKYDYRDLEIIKAVILKAKKSFNSRHEDMHYMLEDIEDEILTSLKRLKKAIHD
                     RGVKGQKETIKSMQAYLMQTILTELEETHALYMRRKNMKQYNIFNQ"
                     /name="replication initiator protein A"
     gene            <1004..1293
                     /locus_tag="HS259_RS00010"
                     /pseudo=""
     CDS             <1004..1293
                     /locus_tag="HS259_RS00010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009384749.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            complement(1492..1872)
                     /locus_tag="HS259_RS00015"
                     /old_locus_tag="SUP_0004"
     CDS             complement(1492..1872)
                     /locus_tag="HS259_RS00015"
                     /old_locus_tag="SUP_0004"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_158139168.1"
                     /translation="MSKSSESFNLHDISPFIKIAILITILNTFILDFKRHFEDLEANHI
                     GFVLKNLYSLLKRKYEPNKYMLISQTKISAKSVTNFLDTAHLHANLKISIKYFKTSPCF
                     SKFLQGFSYQKLRNFNLTLKSP"
                     /name="hypothetical protein"
     gene            complement(2157..2849)
                     /locus_tag="HS259_RS00020"
                     /old_locus_tag="SUP_0005"
     CDS             complement(2157..2849)
                     /locus_tag="HS259_RS00020"
                     /old_locus_tag="SUP_0005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative immunity/bacteriocin fusion bifunctional
                     protein"
                     /protein_id="WP_000691527.1"
                     /translation="MKIIKLFSIISLFLLVFSANFSNAYANEEQKSSLLENQKEKLKSK
                     NIEVSQMTKKEISFLEQLQNKNEDMQKFEKQMKKEGFKKIKLEDKNSKLKYLATEANDK
                     NAYGYIANNAYKNEKTKEIVVSETIYDNYNKKITKFIAEKRSMTENKEGKILINKNYVE
                     YKAEKVDKNRPVTYAGFKWNGKAFACSMAGLYACAHYCGVWAIVNPIAGGVCEAVCGTA
                     FAAGCSVG"
                     /name="putative immunity/bacteriocin fusion bifunctional
                     protein"
     gene            2959..3153
                     /locus_tag="HS259_RS00025"
                     /old_locus_tag="SUP_0006"
     CDS             2959..3153
                     /locus_tag="HS259_RS00025"
                     /old_locus_tag="SUP_0006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001004925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001004925.1"
                     /translation="MNENLEKYIKSLPLLGLLISILLIVLFFFILDVDEDLFVVFLYCL
                     LPLIVNLSIYGFYVFVKRK"
                     /name="hypothetical protein"
     gene            4269..4886
                     /gene="cadD"
                     /locus_tag="HS259_RS00030"
                     /old_locus_tag="SUP_0009"
     ARG             4270..4883
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            4905..5252
                     /locus_tag="HS259_RS00035"
                     /old_locus_tag="SUP_0010"
     CDS             4905..5252
                     /locus_tag="HS259_RS00035"
                     /old_locus_tag="SUP_0010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119690.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNHEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            5409..5501
                     /locus_tag="HS259_RS00040"
     CDS             5409..5501
                     /locus_tag="HS259_RS00040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(5673..6644)
                     /locus_tag="HS259_RS00045"
                     /old_locus_tag="SUP_0011"
     CDS             complement(5673..6644)
                     /locus_tag="HS259_RS00045"
                     /old_locus_tag="SUP_0011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="WP_000481279.1"
                     /translation="MFNAVVVRKSASNVSYKVEKVDESHLSKGDVLVKVVYSSINYKDM
                     LALQYKGGVIRDYPMIPGIDFAGIVESSSNDKFKEGDNVLVTGYDVGVTHTGGFSEYAQ
                     VPGEWIVPIPQEMSIKESMVYGTAGFTAALSIFELEKYGMNIKSQPEILVSGATGGVGS
                     VAIQILHKIGYENITAIVRKEKQIEIAKKLGAKQVIIIEDDNKPLKKGIFDYFLDTVGS
                     NVTLYGLKRLNYQGVATVCGNVAGNSLNANILPFILRGIKLIGIDSVYVDHNIREDIWS
                     KLANEWNIGNSLLYNEIGFEEFYKTIDQLLKGQHLGRTILKV"
                     /name="oxidoreductase"
     gene            6768..7187
                     /locus_tag="HS259_RS00050"
                     /old_locus_tag="SUP_0012"
     CDS             6768..7187
                     /locus_tag="HS259_RS00050"
                     /old_locus_tag="SUP_0012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418034.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_000418035.1"
                     /translation="MELDNCINYLLSTSQNRVFKHFKSLLSPYNITPAEYGVLNCLINS
                     NLNTPKAIGNTLNLEPSTISGILDKMSKKDLITRQTDNENRRTVLINSTNKAKDLWPTL
                     EKKAYQLNNHYFANLTNEETVVFKKILLKINKTTF"
                     /name="MarR family transcriptional regulator"
     gene            complement(7713..8558)
                     /gene="blaZ"
                     /locus_tag="HS259_RS00055"
                     /old_locus_tag="SUP_0013"
     ARG             complement(7717..8558)
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            8665..10422
                     /gene="blaR1"
                     /locus_tag="HS259_RS00060"
                     /old_locus_tag="SUP_0014"
     ARG             8666..10419
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.38"
                     /coverage="100.0"
     gene            10412..10792
                     /gene="blaI"
                     /locus_tag="HS259_RS00065"
                     /old_locus_tag="SUP_0015"
     ARG             10413..10789
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="98.41"
                     /coverage="100.0"
     gene            11056..11634
                     /locus_tag="HS259_RS00070"
                     /old_locus_tag="SUP_0016"
     CDS             11056..11634
                     /locus_tag="HS259_RS00070"
                     /old_locus_tag="SUP_0016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690624.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690637.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLNLLKTLYDNGTPI
                     KTIAEQWQVSRTTIYRYLNKLEAKENKNK"
                     /name="recombinase family protein"
     gene            12304..12978
                     /locus_tag="HS259_RS00075"
                     /old_locus_tag="SUP_0018"
     CDS             12304..12978
                     /locus_tag="HS259_RS00075"
                     /old_locus_tag="SUP_0018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105991.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(13147..13718)
                     /locus_tag="HS259_RS00080"
                     /pseudo=""
     CDS             complement(13147..13718)
                     /locus_tag="HS259_RS00080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /name="HTH domain-containing protein"
     gene            complement(13994..14788)
                     /gene="aph(3')-IIIa"
                     /locus_tag="HS259_RS00085"
                     /old_locus_tag="SUP_0021"
     ARG             complement(13998..14788)
                     /name="aph(3')-IIIa"
                     /gene="aph(3')-IIIa"
                     /gene_name="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(14881..15411)
                     /gene="sat4"
                     /locus_tag="HS259_RS00090"
                     /old_locus_tag="SUP_0022"
     ARG             complement(14885..15411)
                     /name="sat4"
                     /gene="sat4"
                     /gene_name="streptothricin N-acetyltransferase Sat4"
                     /tool="amrfinderplus"
                     /drug_class="STREPTOTHRICIN"
                     /identity="97.78"
                     /coverage="100.0"
     gene            complement(15408..>16043)
                     /locus_tag="HS259_RS00095"
                     /pseudo=""
     CDS             complement(15408..>16043)
                     /locus_tag="HS259_RS00095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009251744.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /name="aminoglycoside 6-adenylyltransferase"
     gene            complement(16184..16858)
                     /locus_tag="HS259_RS00100"
                     /old_locus_tag="SUP_0025"
     CDS             complement(16184..16858)
                     /locus_tag="HS259_RS00100"
                     /old_locus_tag="SUP_0025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="WP_001105956.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(<16915..17091)
                     /locus_tag="HS259_RS00105"
                     /old_locus_tag="SUP_0026"
                     /pseudo=""
     CDS             complement(<16915..17091)
                     /locus_tag="HS259_RS00105"
                     /old_locus_tag="SUP_0026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499250.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016311 - dephosphorylation [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /name="undecaprenyl-diphosphate phosphatase"
     gene            complement(17105..17842)
                     /locus_tag="HS259_RS00110"
                     /old_locus_tag="SUP_0027"
     CDS             complement(17105..17842)
                     /locus_tag="HS259_RS00110"
                     /old_locus_tag="SUP_0027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000369394.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="WP_000369394.1"
                     /translation="MDNLLRTEFIKLKRSYMFLISILGTCVAPFMVVVASFISMRTKVP
                     TPNIVFKQLFEEVSLYHMLIIGPPLYGVIIAYLFGREYIEDTLKNLLIIPISRESFLVS
                     KIILLFLWIQTLSVIAWLLTLMLGMLLHFQGLSQSLIIDSFFTFVIGGVLLWILSPPII
                     ILSIYFKNYVPTIVLTIIITLINLMTANSEHRGLFPWAAVGDISRGTLPNTYPFLLSLI
                     IIIVTSIFSVIILFSYFKKTDIS"
                     /name="ABC transporter permease"
     gene            complement(17835..18764)
                     /locus_tag="HS259_RS00115"
                     /old_locus_tag="SUP_0028"
     CDS             complement(17835..18764)
                     /locus_tag="HS259_RS00115"
                     /old_locus_tag="SUP_0028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000074567.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0005524 - ATP binding [Evidence IEA];
                     GO:0016887 - ATP hydrolysis activity [Evidence IEA];
                     GO:0042626 - ATPase-coupled transmembrane transporter
                     activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000793446.1"
                     /translation="MKNLNNIIEINNLTKQYGSQIAVNNLSITVESGQIYGFLGRNGAG
                     KTTTIRMLLGLIKPTKGNIKIFEKEFESNKTEILKNIGAMVETPGFYSNLTAKENLTIN
                     AKILGIQKENAIEEVLEIVGLASEKVKLFKNYSLGMKQRLGIARALLHNPELLILDEPT
                     NGLDPIGIKEIRKLIKDLAQSRNITILISSHILSEIEQLVDKVGIIHNGVLLEEIMYED
                     LKKKNRQFISISVSDEEKVACLLETNFGIYDYKIKENGEFKIYSHIDRQQEINRLLVLN
                     NIDVFQMRVIEDNLETYFEDLVGGGTIG"
                     /name="ABC transporter ATP-binding protein"
     gene            complement(18880..19761)
                     /locus_tag="HS259_RS00120"
                     /old_locus_tag="SUP_0029"
                     /pseudo=""
     CDS             complement(18880..19761)
                     /locus_tag="HS259_RS00120"
                     /old_locus_tag="SUP_0029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015581923.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA];
                     GO:0000155 - phosphorelay sensor kinase activity [Evidence
                     IEA]; GO:0004673 - protein histidine kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /name="sensor histidine kinase"
     gene            complement(19758..>20135)
                     /locus_tag="HS259_RS00125"
                     /old_locus_tag="SUP_0030"
                     /pseudo=""
     CDS             complement(19758..>20135)
                     /locus_tag="HS259_RS00125"
                     /old_locus_tag="SUP_0030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019834602.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]; GO:0006355 - regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /name="response regulator transcription factor"
     gene            complement(20193..20867)
                     /locus_tag="HS259_RS00130"
                     /old_locus_tag="SUP_0031"
     CDS             complement(20193..20867)
                     /locus_tag="HS259_RS00130"
                     /old_locus_tag="SUP_0031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="WP_001105960.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            21341..22807
                     /gene="msr(A)"
                     /locus_tag="HS259_RS00135"
                     /old_locus_tag="SUP_0032"
     ARG             21342..22804
                     /name="msr(A)"
                     /gene="msr(A)"
                     /gene_name="ABC-F type ribosomal protection protein Msr(A)"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE/STREPTOGRAMIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            22906..23805
                     /locus_tag="HS259_RS00140"
                     /old_locus_tag="SUP_0033"
     CDS             22906..23805
                     /locus_tag="HS259_RS00140"
                     /old_locus_tag="SUP_0033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mph(C) family macrolide 2'-phosphotransferase"
                     /protein_id="WP_000196697.1"
                     /translation="MTRHNEIIKCAEKYQLHIQPQTISLNESGLDFQVAFGKDKHGVEW
                     VLRLPRRPDVYKRTKPEKQTVDFLQKNVSFEIPKWKVHAKDLIAYPKLTGKPAATIDPE
                     IQNYVWEIEHKPLPENFINTLAETLVDLHNIPEENINVQHINIKTIQEIKNDFQRRMNK
                     VKETYGVSDELWNRWKQWLENDELWPRHATMIHGDLHPGHIMVDNQANVTGLIDWTEAT
                     HSDPSMDFIGHHRVFDDEGLEQLITAYGKAGGEIWPRMKEHIIELNAVFPMFIAEFAME
                     SGESAYETMALKELGMKE"
                     /name="Mph(C) family macrolide 2'-phosphotransferase"
     gene            24291..24899
                     /locus_tag="HS259_RS00145"
                     /old_locus_tag="SUP_0034"
     CDS             24291..24899
                     /locus_tag="HS259_RS00145"
                     /old_locus_tag="SUP_0034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002474535.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000583528.1"
                     /translation="MIIGYARVSSIDQNLERQLDNLKTFGVEKIFTEKQSGKSVENRPV
                     FQEALNFVRMGDRFVVESIDRLGRNYDEIIETVNYLKEKDVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRV
                     IYHRVVEMLEEGKAISKIAKEVNITRQTVYRIKHDKGLS"
                     /name="recombinase family protein"
     gene            25145..25483
                     /locus_tag="HS259_RS00150"
                     /old_locus_tag="SUP_0035"
     CDS             25145..25483
                     /locus_tag="HS259_RS00150"
                     /old_locus_tag="SUP_0035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001049146.1"
                     /translation="MNLIPFIIILIFSCLWTAITNKYLPSETLDKKGQQDRYDERQRKM
                     FIEILAKSFIWIVYCMLFTLVLKFTGLSPSIEGSWFSQYPEIFFIIVALFLMLFNYYTT
                     NKKYTSKG"
                     /name="hypothetical protein"
     gene            25488..25673
                     /locus_tag="HS259_RS00155"
                     /old_locus_tag="SUP_0036"
     CDS             25488..25673
                     /locus_tag="HS259_RS00155"
                     /old_locus_tag="SUP_0036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011276570.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000797248.1"
                     /translation="MKNRIREYRKQKGISQETLSKELKVSRQTINAIENNKYDPTLTLA
                     FKLARLFDTTVDELFS"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(25900..26643)
                     /locus_tag="HS259_RS00160"
                     /old_locus_tag="SUP_0037"
     CDS             complement(25900..26643)
                     /locus_tag="HS259_RS00160"
                     /old_locus_tag="SUP_0037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843732.1"
                     /translation="MKSVKKLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESTTEDKQKKGSDNINFESKSDAQIVEILKNQIDTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNTR
                     QNVDAQEKTYTTNPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAKKEDVPANLND
                     NDSDIEEKSEETEPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     ARG             22907..23802
                     /name="mph(C)"
                     /gene="mph(C)"
                     /gene_name="Mph(C) family macrolide 2'-phosphotransferase"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             21342..22807
                     /name="msrA"
                     /gene="msrA"
                     /gene_name="msr-type ABC-F protein"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; streptogramin
                     antibiotic; streptogramin B antibiotic"
                     /identity="98.36"
                     /coverage="100.0"
     ARG             22907..23805
                     /name="mphC"
                     /gene="mphC"
                     /gene_name="macrolide phosphotransferase (MPH)"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="98.66"
                     /coverage="100.0"
     ARG             complement(14882..15399)
                     /name="SAT-4"
                     /gene="SAT-4"
                     /gene_name="streptothricin acetyltransferase (SAT)"
                     /tool="rgi"
                     /drug_class="nucleoside antibiotic"
                     /identity="97.16"
                     /coverage="95.56"
     ARG             complement(15706..16007)
                     /name="aad(6)"
                     /gene="aad(6)"
                     /gene_name="ANT(6)"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="99.0"
                     /coverage="36.23"
     ARG             complement(7714..8558)
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     Typing          1350..1497
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="5.980000000000001e-72"
     Typing          2..984
                     /name="rep_cluster_2100"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.593"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          1116..1285
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="93.605"
                     /coverage="91.0"
                     /evalue="1.04e-65"
     Typing          complement(25901..26643)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 atgcaaaatc aatattttac agtgcaagaa aattacaaag aaagatttta tcaaatccct
       61 aaagtattct ttaccagtga aaattataaa aatctaacta atgatatgaa aatagcctat
      121 gctatcttac gtgatcgctt aaatttatct attaaaaata gctgggttga tgaagatggt
      181 aacatttact ttgtttattc aaatgaaaag ctaatggaaa tcttaaattg taaaaaagaa
      241 aagttaacaa aaataaaaaa agggttagaa aacgatggtc tactcattca aaaacgacgt
      301 ggtttaaata aaccaaatat tctatattta atgaaaccta ttgtcacaga acgtgatatt
      361 tacaaaatag aaaaagaaga aaacgatgtt gaaccttacg gcgagaagga agttcgaaaa
      421 tcgaacgtcc agaagttcga aaatcgaacg tccagaagtt cgaaaatcga acgtccagaa
      481 gttcgaaaat cgaacactaa tgatactgac tttaatgaca ttgactttaa tgatactgag
      541 aataatgata tgaatgactt gaatgatata aagtacaaaa atgaaattag taatcattca
      601 aatcattcaa atcaatttac acataatttt gatgataaag aaatgctatt gcaagaattc
      661 ccagaacaac taactaatta tttattaaaa tatgattata gagatttaga aatcataaag
      721 gctgttattc ttaaagcaaa aaaatcattt aattcaaggc atgaagatat gcattacatg
      781 ttagaggaca ttgaggatga aatattaact tctttaaaaa gacttaaaaa agctatacat
      841 gataggggag ttaaaggcca aaaggaaaca atcaagtcaa tgcaagctta tttaatgcaa
      901 acaattctaa ctgaacttga agaaacacat gccctttata tgcgccgtaa aaacatgaaa
      961 caatataata tctttaatca ataattcaaa tgattttata acactcgaag agacatcaaa
     1021 atattccgtt aaatcatctg actttttaac tgatgacgac gaaaaaaatc aagaaattgt
     1081 aagtgattta gaaaaaggtt tgtatcgaaa acgtatgtta agttatggtg gattgcttaa
     1141 acaaaagcat aaaattttaa acttagacga tgccgaagat ggtaatttga ttaatacaag
     1201 tgatgaagat aaaacgacag acgaagaaaa aaagcacatt caattaccgc aatttggaat
     1261 ttcgaaaagc aaaattatta tttaagacat tagtgataac tgatgtcttt ttttattgtt
     1321 tttctgtaaa aaagtgctgt cttatttttg tgacaaatgc tgtatgtagt gtcacaaaag
     1381 tgtgacacta cagctttgta tgatatcact ttaaaataac ttaaaaccct tggaatgtct
     1441 ggccttgcca gatctatcat ttttgaatga tagcaaattt cccttatgct cttacggaga
     1501 ttttagagtt aaattaaaat ttctaagttt ttgataagaa aagccctgca ggaatttaga
     1561 aaaacatggg gaagttttaa agtattttat gctaattttt aaatttgcat gtaaatgggc
     1621 agtatctaaa aaattagtca ctgattttgc tgaaattttt gtttgtgaaa ttagcatata
     1681 tttatttggc tcatatttgc gttttaagag actgtataga tttttaagta caaaacctat
     1741 atgatttgcc tctaagtctt caaaatgcct cttaaaatcc aaaataaaag tgtttaatat
     1801 tgtaataagg attgctattt ttataaaagg agagatatca tgaagattaa aactttcgct
     1861 acttttactc atcgtcaatt agataaacaa gttaataggt ttttaaagaa tgatattcat
     1921 gtattagaaa ttcaaacaca cagtaattgg ttatatattt cagctattgt tttttatgag
     1981 gataaataag gaacatcgta tttatgccga aaaaatttat tgatgttgag aagaaccctt
     2041 aactaaactt gcagacgaat gtcggcatag cgtgagctat taagccgacc attcgacaag
     2101 ttttgggatt gttaagggtt ccgaggctca acgtcaataa aacaattgga ataaaatcaa
     2161 cctacagagc atccagctgc aaatgcagtt ccgcaaactg cttcacatac accgccggct
     2221 attggattta cgattgccca tactccacag tagtgagcac atgcataaag tccagccata
     2281 ctacaagcga atgctttgcc gttccatttg aatcctgcat atgttaccgg tctgttttta
     2341 tcaacttttt cagccttata ttcaacgtaa tttttgttaa taagtatttt tccctctttg
     2401 ttttcagtca tacttctttt ttcggcaatg aattttgtga tttttttgtt gtagttatca
     2461 tatattgttt cagaaactac aatttctttt gttttttcat ttttataagc gttattagct
     2521 atgtagccat atgcattttt atcatttgct tctgtagcta gatattttaa tttagaattt
     2581 ttgtcttcta gctttatttt tttaaatcct tcttttttca tttgcttttc gaatttttgc
     2641 atatcttcat ttttattttg caattgttct agaaaactta tttctttctt ggtcatttgt
     2701 gatacttcga tgtttttgct tttcaatttt tctttttgat tttctagtaa agaacttttt
     2761 tgttcttcat ttgcgtaagc attagaaaaa ttcgcgctaa ataccagtag gaacaaggaa
     2821 attattgaaa ataattttat aattttcatt tgatacctcc aagataataa gatattttaa
     2881 ttgtataagt aagcgcttta taaaatcaat atttatttta atatatttat aaacatattt
     2941 ttgaaaggag tctattttat gaatgaaaat ttagaaaaat atataaaaag tttgccactt
     3001 ttaggtttgt taattagtat tttgttaatt gttttattct tttttatttt agatgttgat
     3061 gaagatttat tcgtggtttt tttatactgt ttattgcctt tgatagttaa tttgtctatt
     3121 tatggttttt atgtttttgt taaaagaaag taagattatg aataattttg tttttaattt
     3181 gtatgctttg agggggttgg aaaacggtag gtgtatagat tagatttctt gtttttttga
     3241 aacgagtgtg aacgagtttc ttcttgtctt gatttttgat aaaaacgccc tacaggaatt
     3301 tagaaaaacg tggggaagtt ttaaagaatt ttatgctaat ttttaatttg catgtaaatg
     3361 ggcagtgtct aaaaatagtt attgtttttg ctcaaatttt tgtttttgaa aatagcatat
     3421 atttatttgg ctcatatttg cgttttaaaa gcatatataa gttttagata taaaactata
     3481 tgaatcaccc ctaaatcttt aaaatgccct cttaaaattc aaaataaggg cataaaaaat
     3541 aaaagctacc ccagataaag tgaggtagct ttttctttca tacggtctat ttatttttct
     3601 ttcgacgccg tatcgtcgat gtaattcaaa aaagttatgg gctataaatc tacatcactt
     3661 tttcaagaat gtagtagcaa tattcaacgc aaattaattt ttataactgc tcggaatatc
     3721 tcaagccgtt tctttaattt tgaaataaaa aaatcgacga aggtcgatta cgtttttgca
     3781 catgtcgatt tatccgacgt ataagtgcgc ccttacggga tttaactaga ttataacgac
     3841 gaattttaga cctgtaaagc aataacaatt aggtctacca ggtagataaa gtgtacaaag
     3901 tagaaccgaa aaagttattt attttgaaga tttttcgtag atataatttg ctaataaact
     3961 tcctaaaact gaataaagaa aaatagttaa actcatgtaa tcactccata attctgaagt
     4021 gtctccatgt ctacgcatag acacgcattt atgccgaaaa aatttattga tgttgagaag
     4081 aacccttaac taaacttgca gacgaatgtc ggcatagcgt gagctattaa gccgaccatt
     4141 cgacaagttt tgggattgtt aagggttccg aggctcaacg tcaataaagc aattggaata
     4201 aagcacctat gattatttaa aaatataagt tataatacat tcaaaaatat ttttgaatga
     4261 ggtgtattat gattcaaacg gttgttgctg ctgctgttct ttatattgct acagcagttg
     4321 atttattagt aattttatta atattttttg ctagagcaaa gactagaaaa gaatatagag
     4381 atatttatgt tggtcaatat ttagggtcta ttattttaat attagttagt ttgtttttag
     4441 cttttgtatt aaattatgtt ccagaaaagt ggatattagg tttattgggt ttaataccaa
     4501 tttatcttgg aattaaagtg gctatttatg atgattgtga aggagaaaag agagctaaaa
     4561 aagaattgaa tgaaaaagga ttgtctaaat tagttggtac ggttgcaatt gttacgatag
     4621 caagttgtgg cgccgataat attggtttat ttgttccgta ttttgtgaca ttaagtgtta
     4681 ctaatttatt acttactctg tttgtctttt taattttaat tttcttcttg gtgtttactg
     4741 cacaaaaatt agctaatatt ccaggaattg gagaaattgt tgagaaattt agtcgttgga
     4801 ttatggctat tatttatata gctttaggtt tatttattat tattgaaaat gacactattc
     4861 aaacaatttt aggatttata ttttaattta gggtgtgatt ttatatgagt tatgaaaata
     4921 cttgtgatgt gatctgtgta catgaggata aagttaacaa tgctttaagt tttttagaag
     4981 atgataaatc taagaaatta cttaacattt tagaaaaaat ttgtgatgag aagaaattga
     5041 aaatcatatt atctttgatt aaagaagatg agttgtgtgt ttgtgatatt tctttgatat
     5101 tgaaaatgag tgttgcttca acttcacatc atttaaggct tttatataaa aatgaggtac
     5161 ttgattttta taaagatgga aagatggcat attattttat taaagacgat gaaataagag
     5221 agtttttctc taaaaatcat gagggttttt gaaacgagtt tcttcttgtc ttgatactat
     5281 aaaaaacaaa gttatataac ataagacgac ttatcggaag tagatatgct tgtatattca
     5341 cagatggtat aataatagag tcgcctatct ctcaggcgtc aattgacgaa gagaggaggt
     5401 gcattacttt gctaatcatt ttcgttcaca tcatagcacc agtcatcagt ggctgtgctg
     5461 ttgcgtatta tacttattgg cttagtaaac gcaacaaata attaataggc gactttataa
     5521 gccagcatcg aaaaaatccc cacactactg caatagtgtg gggattggtg cattaattgt
     5581 taatcatttt cgttatataa attataacac tggttagtag agaaatgcaa aatgattgaa
     5641 ttaatagtaa atgtattaat gaatactcac acttatactt ttaaaatagt tcttcctaaa
     5701 tgttgtcctt ttaaaagctg atctatcgtt ttatagaatt cttcaaatcc aatttcattg
     5761 tatagaagtg aatttcctat attccattca tttgctaact tactccatat atcttcacgg
     5821 atattatgat caacatatac agaatcaatg ccaattaatt taatacctct aagaataaac
     5881 ggtaatatat tagcgttaag tgaatttcct gctacatttc cacatacagt agcaacacct
     5941 tgataattta gacgttttaa accgtataat gttacattac tccccactgt atctaagaaa
     6001 taatcaaaaa tacctttttt aagcggttta ttatcatctt caattattat tacttgtttt
     6061 gcacctaatt tttttgcgat ttctatttgc ttttcttttc ttacgatagc agtgatattt
     6121 tcatatccaa ttttatgtaa aatttgtata gcaacactgc ccacaccacc tgtagcccca
     6181 gacactaaaa tttcaggttg tgatttgata ttcattccat atttttctag ttcaaaaatt
     6241 gataatgctg ccgtaaaacc ggctgtgcca tataccatag actctttaat agacatttct
     6301 tggggaatag gaacaatcca ctctccaggc acttgtgcat attctgaaaa tccacctgta
     6361 tgtgtcacgc caacatcata accagtaact aatacattat cgccttcttt aaacttatca
     6421 ttcgaacttg attcaacaat acctgcaaaa tctataccag gaatcatagg ataatctcta
     6481 attacaccgc ctttatattg taaagctagc atatccttat aatttattga agagtatacc
     6541 acttttacta atacatcacc cttcgataaa tgagattcat caactttttc tactttataa
     6601 ctaacatttg atgcactttt tctcactact accgcattga acatttatta gccttctttc
     6661 acaattgttt tgtagaagta tgtttttgtt gcaaaactat tttcctacaa aacttatcat
     6721 gatatgataa gcgagtcaat actaatgatt taagagaggt tttagttgtg gaattagata
     6781 attgtataaa ttatttgttg agtacttctc agaatagagt ttttaaacat tttaaaagtt
     6841 tattaagtcc ctataatatt actccagcag aatatggtgt tttgaattgc ttgattaata
     6901 gtaatttgaa tacacctaaa gcgattggta atactttaaa tttagaacct tcaacaatat
     6961 ctggaatatt agataagatg tccaaaaagg atctaataac acgtcaaact gataatgaaa
     7021 atagaagaac tgtgctaata aacagtacaa ataaagcaaa agacttatgg ccaacattag
     7081 aaaagaaagc ctatcaactt aataatcatt acttcgctaa tttaactaat gaagaaactg
     7141 tagtgtttaa aaagatatta ctaaagataa ataaaactac gttttaattt ttacgttata
     7201 aaaaagttga agtgcgaatt ataatcgagt aaatataaat gatagcttag cttaattata
     7261 tattaaagcc aactatactt ttattcccga aaaacctact atccaaattt ctaagatact
     7321 ttagcctcta taataaacat attgtaatat aatttatgta ttatttaggt ttaccctaat
     7381 cgaacaataa aaaatacttg taaaatgcta ttgtcacttt gcttgatata tgagaattat
     7441 ttaaccttat aaatgagaaa aaagcaacgc actttaaata agatacgttg ctttttcgat
     7501 tgatgaacac ctataattaa actattcatc tattatttat gattttttgt atatacaata
     7561 tttctagttt gttaaagaga attaagaaaa taaatctcga aaataataaa gggaaaatca
     7621 gtttttgata tcaaaattat acatgtcaac gataatacaa aatataatac aaactataag
     7681 atgttatcag tatttattat gcatttagaa tattaaaatt ccttcattac actcttggcg
     7741 gtttcactta tcaacttatc atttggctta tcacttttat tgtctttatt cgtaaaaatg
     7801 actaaaacaa taggttcaga ttggccctta ggataaacaa aagcaacatc atttctagaa
     7861 gcatatgtta ttgcttgacc acttttatca gcaaccttat agtcttttgg aacaccatct
     7921 ttaattaaag tgtctccgtt tttattatta aacattaaat caagtaagaa atttttattt
     7981 tttttgctta attttccatt tgcgataagt ttatttaaag tcttgccgaa agcagcaggc
     8041 gttgaagtat cttttttgct ctttggtgaa tagtaattta attctatctc atatctaact
     8101 ggatttgtta ctttatctcc tagttctttt agacgttgtt taactttttt gattccaccg
     8161 atttctttta taattttatt gtttgctgta ttatcactat atgtcattga agcctcaata
     8221 agttctttta aagtgatatc ttttcctaca tatttttcta aaataggaga ataagcaact
     8281 atatcatctt tgttaatatg tactttttta tttaacttat tataaggtac ttgttctaac
     8341 aaaatagcac tatttatcgc ttttgaagtc gaagcatagg caaatctctt atctgaatta
     8401 aattttactt ccttaccact tttagtattt aaagcataaa caccaatatg agcattatat
     8461 tttttttcta aatcatttaa ctctttggca tgtgaactgt ttgaattaca tgcacttaaa
     8521 actaaagcaa ttacaattaa aaatattaac tttttcaaaa taaaccctcc gatattacag
     8581 ttgtaatttt tataaatcaa taatattaca attgtaatat tgatgtcaat tgtttattat
     8641 aaatatttga aagaaggtgt caaaatggct aaattactaa taatgagcgt agtaagcttt
     8701 tgttttatat ttctattgtt agtatttttt aggtacatat taaaacgcta ttttaattat
     8761 agtttaaatt ataaagtttg gtatctaact atgcttgctg gattaattcc ttttatccca
     8821 attaaattct cttttataaa atttaataat gtgaataatc aagcgcccac agttgaaagt
     8881 aagtcacacg atttgaacca taacataaat accaccaaac ctattcaaga gttcacaaca
     8941 gatatccata agtttaattg ggattcaatt gataatatct gcacagttat ttggatagtt
     9001 ttagttatta ttttaagttt taaatttttg aaagccttat tatatcttaa atatttaaag
     9061 aaacagtcac tttatctaaa cgaaaatgaa aaaaataaaa tagatacgat acttttcaac
     9121 catcaatata aaaaaaatat tgtgattcga aaagcagagg ctattcaatc tccaataact
     9181 ttttggtatg ggaaatatat tattttgatt cctagttcat attttaaaag tgtaattgat
     9241 aaaagactaa aatatataat actgcatgaa tatgctcatg ctaaaaatag agatacttta
     9301 catttaatta tctttaatat cttctctatt attatgagtt acaatccatt agtacatatt
     9361 gtaaaaagaa agataattca tgacaatgaa gtagaagccg atagatttgt ccttaataat
     9421 attaacaaaa atgaatttaa aacttatgcg gaatctatta tggactccgt attaaaaacc
     9481 ccattttcca acaaaaatat attaagccat tcatttaatg gtaaaaaatc attactcaaa
     9541 agtagattaa ttaatataaa agaagccgat ctgaaaaagc agtcaaaatt aattctaatt
     9601 tttatttgta tttttacttt ttttatcatg ataattcaaa gccagttttt aatggggcaa
     9661 tccttaactg attataatta taaaaagccc ttacaaagcg attaccaaat tttagatgaa
     9721 agtaaaaatt ttggttcaaa tagtggatct ttcgttatgt acagcatgaa gaaagacaaa
     9781 tactatattt ataatgaaaa agaaagtaga aaaagatatt ctcctgattc aacttacaaa
     9841 atttatttag cactgtttgg acttgaccgt catattataa gtgataaaaa ttcacgtatg
     9901 tcatggaatc ataaacatta tcttttcgag tcttggaata aggaacaaga tttaaataca
     9961 gcaatgcaaa attcagttaa ttggtacttc gaacgtatta gtaatcaaat accaaagaac
    10021 tatactgcgg ctcaactcaa gcaattaaat tatggtaatg aaaatttggg aagttataaa
    10081 agctattgga tggaagatag tttgaaaata tctaatcttg aacaagtaat agtttttaaa
    10141 aatatgatgg aacaaaataa ccattttagt aaaaaagcaa agaatcaatt atcttcttca
    10201 ttattgatta agaaaaatga aaagtatgaa ctgtatggga aaacaggtac aggtatagta
    10261 aacgggaagt ataataatgg gtggtttgta ggttacgtaa ttacaaatca tgataagtat
    10321 tattttgcta cacatttatc agatggaaac ccgtctggga aaaatgctga attaataagt
    10381 gaaaaaatat taaaaggaat gggtgtttta aatgaccaat aagcaagttg aaatatctat
    10441 ggctgaatgg gatgttatga atataatatg ggataaaaaa tcagtatcag ctaatgaaat
    10501 tgtagttgaa attcaaaaat ataaagaagt tagtgataaa acgattagaa cattaatcac
    10561 aagactatat aaaaaagaga ttataaaacg atacaaatca gaaaatattt atttttactc
    10621 atcaaatatt aaagaagacg atattaaaat gaaaactgct aaaacctttc ttaataaact
    10681 gtatggaggg gatatgaaaa gtttagtgct gaattttgcg aaaaatgaag aattaaataa
    10741 caaagaaatt gaagaattgc gagacatttt aaatgatatt agtaaaaagt aattagaggt
    10801 atgtttcaaa cataatacat atgtaaacca tacttgactc ttattaaatt agttttgtta
    10861 atgacattta aaatatatta ttaaagatga gagtgtccag aaaataacca ttttctgtac
    10921 actcttgttt tttgtctaaa taagtaagta ttacatagaa ttatgtgttc aaaaacccaa
    10981 caaaaaatct atgttcacaa aagacctcgt aatcaagtta tggtacacta aaggtgtata
    11041 taggaggtct gtattttgaa aataggttat gcaagagttt caactggatt acaaaatttg
    11101 aatttacagg aggatcgatt aaatacatat ggttgtgaaa agatatttaa tgaccatatg
    11161 agtggttcaa aaagtaagcg acctggttta gataaagcaa ttgaatttgc gaggtcagga
    11221 gatacgattg ttgtttggag attagataga ctaggacgga acatggagga tttaatcacg
    11281 ttagttaatg aacttaacga acgaggtgtg agttttcata gtttagaaga aaatataacg
    11341 atggataaat caagttctac aggacaatta ttatttcatt tattcgcagc atttgcagag
    11401 tttgaacgta atttaatttt agagcgatca tcagccggtc gaattgcagc acgtgctaga
    11461 ggccgatatg gaggtagacc tgaaaaatta aataaacaag atttaaactt acttaagaca
    11521 ctttatgata atggtacgcc aattaaaaca attgcagagc agtggcaagt ttcacgtaca
    11581 actatttatc gttatctcaa taaattagag gcaaaagaga ataaaaacaa gtagagcaac
    11641 taatctagct tactataatg aatctactaa ataattttat atatcattaa catacaaaga
    11701 ctttgattca atgtcactcg atgtaaaaga gacgttctga cagcgtctaa aatctcataa
    11761 tattttcctg ttatgagatt ttaataataa cacaagaaaa aagcgtacaa attcgtacgc
    11821 ttttttaata taatacctgt ttcactaatg aacgttttaa gtatcttcat cattaactga
    11881 aactacagta ataatactcg tcaacaatat tagtatagtt aaaatagaaa gacttaggac
    11941 tggcataacc gaactaaaat tatatttgaa atataaaagt gctaatgaag agagaaatgt
    12001 aaaaataata aataccaaag accatttttc taatttattc attggcttca cctctttgaa
    12061 cttttatata atcataggag atatttttac tacgatttat aaaaaataag aagataatca
    12121 ttattaaaga aacgattaat ataatgttga atcctatagt atcacctaat tcgtttacac
    12181 ctttgcctaa tatcggagat acaaagcttt gtattaataa tgaaagagat gcccatatag
    12241 taaatgaggt tctgttgcaa agttgaattt atagtataat tttaacaaaa aggagtcttc
    12301 tgtatgaact atttcagata taaacaattt aacaaggatg ttatcactgt agctgttggc
    12361 tactatctaa gatatgcatt gagttatcgt gatatatctg aaatattaag ggaacgtggt
    12421 gtaaacgttc atcattcaac ggtctaccgt tgggttcaag aatatgcccc aattttatat
    12481 caaatttgga agaaaaagca taaaaaagct tattacaaat ggcgtattga tgagacgtac
    12541 atcaaaataa aaggaaaatg gagctattta tatcgtgcca ttgatgcaga gggacataca
    12601 ttagatattt ggttgcgtaa gcaacgagat aatcattcag catatgcgtt tatcaaacgt
    12661 ctcattaaac aatttggtaa acctcaaaag gtaattacag atcaggcacc ttcaacgaag
    12721 gtagcaatgg ttaaagtaat taaagctttt aaacttaaac ctgactgcca ttgtacatcg
    12781 aaatatctga ataacctcat tgagcaagat caccgtcata ttaaagtaag aaagacaagg
    12841 tatcaaagta tcaatacagc aaagaatact ttaaaaggta ttgagtgtat ttacgctcta
    12901 tataaaaaga accgcaggtc tcttcagatc tacggatttt cgccatgcca cgaaattagc
    12961 atcatgctag caagttaagc gaacactgac atgataaatt agtggttagc tatatttttt
    13021 tactttgcaa cagaaccagc atttgtttta atatttgttc caaagagcca tcatggcttt
    13081 gacagagctc ttcttctatg caaatgcttt taatccgatc cacacgaaaa ttcctatatt
    13141 catttcttag cctgcaaaac cgattaagta ccagttctgt tcataaaacc ccagtgatat
    13201 aggctctatc attctgcttt ccggttcttg ccctcctgat gcaggatatt gaattgatat
    13261 taccctttta ttgcagattg cagtctgaat tgctgcaata acgttatccg ccaatgtatt
    13321 tttctgtcca gatgtgctgt acacgttaat actgttctcc aactcctgtg catagttttt
    13381 ttcaccatgc ttcaaaatag atttgatttt atacatagct gaatcaaaat cctttataaa
    13441 tgattcatct ccatggcaat ttaaaaattt ccctgctgta atcaatgcac ccacttccgc
    13501 cgctgtaaac attaccggca gaagtaggaa gccctctaca agaaaatatc cttttccggc
    13561 ctcagatcca attggtattc cggcttcttc aagtgtccgg atatctctgt aaactgtcct
    13621 taagcttata ttaaatcgct gtgcaatttc tttggcagga attatttttt tgattgcagc
    13681 tgaataagaa tagaggttac tctgttaatc ctgttcaaat tttattcctc ctctgtgact
    13741 tccataaaaa gtatatccta tgcgttctta agctagctgc tgttagtgct tctcattgca
    13801 ccctggttat aaaagccata ctcacaaacc tcttcaccaa aactctttac atctctaata
    13861 tagaactcta tctagcgaac ttttagaaaa gatataaaac atcagagtat ggacagttgc
    13921 ggatgtactt cagaaaagat tagatgtcta aaaagcttgt agttaaagct ttttagacat
    13981 ctaaatctag gtactaaaac aattcatcca gtaaaatata atattttatt ttctcccaat
    14041 caggcttgat ccccagtaag tcaaaaaata gctcgacata ctgttcttcc ccgatatcct
    14101 ccctgatcga ccggacgcag aaggcaatgt cataccactt gtccgccctg ccgcttctcc
    14161 caagatcaat aaagccactt actttgccat ctttcacaaa gatgttgctg tctcccaggt
    14221 cgccgtggga aaagacaagt tcctcttcgg gcttttccgt ctttaaaaaa tcatacagct
    14281 cgcgcggatc tttaaatgga gtgtcttctt cccagttttc gcaatccaca tcggccagat
    14341 cgttattcag taagtaatcc aattcggcta agcggctgtc taagctattc gtatagggac
    14401 aatccgatat gtcgatggag tgaaagagcc tgatgcactc cgcatacagc tcgataatct
    14461 tttcagggct ttgttcatct tcatactctt ccgagcaaag gacgccatcg gcctcactca
    14521 tgagcagatt gctccagcca tcatgccgtt caaagtgcag gacctttgga acaggcagct
    14581 ttccttccag ccatagcatc atgtcctttt cccgttccac atcataggtg gtccctttat
    14641 accggctgtc cgtcattttt aaatataggt tttcattttc tcccaccagc ttatatacct
    14701 tagcaggaga cattccttcc gtatctttta cgcagcggta tttttcgatc agttttttca
    14761 attccggtga tattctcatt ttagccattt attatttcct tcctcttttc tacagtattt
    14821 aaagataccc caagaagcta attataacaa gacgaactcc aattcactgt tccttgcatt
    14881 ctaaaacctt aaataccaga aaacagcttt ttcaaagttg gcgtataaca tagtatcgac
    14941 ggagccgatt ttgaaaccac aattatgata gaatttacaa gctataaggt tattgtcctg
    15001 ggtttcaagc attagtccat gcaagttttt atgctttgcc cattctatag atatattgat
    15061 aagcgcgctg cctatgcctt gccccctgaa atccttacat acggcgatat cttctatata
    15121 agcgtaccgg ttccaatttt ttcgcagttt aacttttccg acgcatttat cgtcttggta
    15181 gtaaagatat attatcttat cagtattgtc aatatattca aggcaatctg cctcctcatc
    15241 ctcttcatcc tcttcgtctt ggtagctttt taaatatggc gcttcataga gtaattctgt
    15301 aaaggtccaa ttctcgtttt catacctcgg tataatctta cctatcacct caaatggttc
    15361 gctgggttta tcgatatctt tcaggtgccc tgctttcatt tctgtaatca ctgttcccgc
    15421 ctctcttcta tatcagcggc atatgtgcta tccaggcagc cggttttacc agtgtatttt
    15481 ttatacatgt ccctggtata ttttgttata ttcctatcat actccggata ggcataatga
    15541 agcctttccg ccacctcacc ggataccgcc ctgaacaatt gatggcatag aaataatgct
    15601 tcccatatgt tttcatagga atccatccgg taggtggaca aaagtttctc ccacaaatcc
    15661 tcggatatat acctttcaat aaacttatag ttcttgccta cacttcattt aaagcctgtt
    15721 tcgatgccga ccttccatga tatcattctc agcagctcat ggcgaacaat ctgattaaaa
    15781 tgatcaatag caaataaaat ttccttacgg cacaatcctt taataacata aggtgttaca
    15841 ttccaaaatt cattgcagca atcatcatac tcccttgcgc ttggctttct tacatgataa
    15901 tctatatcag tcggaactat gtccctttta attctacaat ctttatcaat tagaaccttt
    15961 attaatttat cgccctttag gtaattatct aactcttcca agggcaataa ggtaagatca
    16021 attttattgt aatcatcaaa tagctataat agatttagag gtaaagaaat taaatacatt
    16081 gaagagcaga aagattttac aaaagagtat tttaataaaa atgatggttc tgttgcaaag
    16141 taaaaaatat agctaatcac taatatatca tgtcagtgtt cgtttaactt gctagcatga
    16201 tgctaatttc gtggcatggc gaaaatccgt agatctgaag agacctgcgg ttctttttat
    16261 atagagcgta aatacactca atacctttta aagtattctt tgctgtattg atactttgat
    16321 accttgtctt tcttacttta atatgacggt gatcttgctc aatgaggtta ttcagatatt
    16381 tcgatgtaca atggcagtca ggtttaagtt taaaagcttt aattacttta accattgcta
    16441 ccttcgttga aggtgcctga tctgtaatta ccttttgagg tttaccaaat tgtttaatga
    16501 gacgtttgat aaacgcatat gctgaatgat tatctcgttg cttacgcaac caaatatcta
    16561 atgtatgtcc ctctgtatca atggcacgat ataaatagct ccattttcct tttattttga
    16621 tatacgtctc atcaatacgc catttgtaat aagctttttt atgctttttc ttccaaattt
    16681 gatataaaat tggggcatat tcttgaaccc aacggtagat cgttgaatga tgaacgttta
    16741 caccacgttc tcttaatatt tcagatatat cacgatagct caatgcatat cttagatagt
    16801 agccaacggc tacagtgata acatccttgt taaattgttt atatctgaaa tagttcatac
    16861 agaagactcc tttttgttaa aattatatta taaattcaac tttgcaacag aacctcctaa
    16921 ctgtattacc accttaaaag tagttgcaga cgcacttcct aaatcgtcag cagtgtttaa
    16981 ccacatatca tcaacaataa tcatatgacc tgttgatgat actggagcaa attctgtcaa
    17041 cccttcaact acacctaaaa taaatgcttt aatctgctct ataaaaccca tttttctcct
    17101 ccttttaact tatatcagtt tttttaaagt atgagaataa tataattaca ctgaatatag
    17161 atgtaacaat tatgataatt aaagataata gaaatggata agtattaggt aatgttcctc
    17221 tagatatgtc tccaactgca gcccaaggaa ataatcctct atgttcagaa ttagcagtca
    17281 ttaaatttat caaagtaatt attatggtta aaacaattgt gggaacataa tttttaaaat
    17341 atatcgacaa aataattatt ggtggagata atatccataa taacactccg ccaataacaa
    17401 atgtaaagaa tgaatcaatt attaaactct ggcttaaccc ttgaaaatgc aatagcatac
    17461 ctagcattaa agttagcaac catgcaataa cagatagtgt ttgaatccac aagaataata
    17521 atattatttt acttactaaa aaactttctc tagatatagg tataattaat aagtttttta
    17581 aagtatcttc tatatattct cttccaaaca aataggctat tataacccca tatagaggag
    17641 gtccaataat tagcatatga tataaactga cttcttcaaa taactgttta aatacaatat
    17701 taggagtcgg tactttcgtc cgcatactaa taaaagaagc tacaaccacc ataaaaggtg
    17761 ctacgcatgt acctaaaata cttattagaa acatatatga tctttttaac ttaataaatt
    17821 ctgtacggag tagattatcc aattgtgcca cctcctacta agtcttcgaa ataagtttct
    17881 agattatctt ctatcactct catctggaaa acatcaatat tgtttaatac taataatcta
    17941 ttaatttctt gttgtctatc aatatgtgaa taaattttaa attcgccatt ttctttaatt
    18001 ttatagtcat aaattccgaa gttagtttcc aacaaacatg caactttttc ttcatctgat
    18061 actgatatac ttataaattg tctgttcttt ttttttaaat cttcatacat aatttcttct
    18121 aacaaaactc cgttatgaat aatacccacc ttgtctacta actgctctat ttctgacaat
    18181 atatgacttg aaattaaaat ggttatattt ctagattgag ccagatcctt aatcaacttt
    18241 ctaatttctt ttatgccaat aggatctaat ccattcgtcg gctcatcaag tatcaataat
    18301 tcgggattgt gcaataaagc tctcgcaatc cctaaacgtt gcttcatacc taaagaataa
    18361 tttttaaaca attttacttt ttcagaagct agtcctacta tttctaacac ttcttcaatt
    18421 gcattttctt tttgtatacc taatatttta gcatttatag ttaagttctc tttagctgtc
    18481 aaattactat aaaaacctgg cgtttcaacc atagcaccaa tattttttaa aatttcagtt
    18541 ttattacttt cgaactcttt ttcaaatatt ttaatattac ctttcgtagg tttaattaag
    18601 cctaaaagca ttcttatagt agttgttttg cctgcaccat ttcttcctaa aaaaccataa
    18661 atttgtccac tttcaacagt tatactcaaa ttattaactg ctatctgact tccatattgc
    18721 tttgttaagt tatttatttc aattatatta ttcaaatttt tcacctctgg cacctttctt
    18781 agtttgttgt tacctttatc ttacgcgcga ttagaaaagg ctgcctttat ctattcttac
    18841 aaaaacagcc gctaatctta caaaaatgaa agattggagt tatttaaatt gaatggtgaa
    18901 tattgaacca tcgtttaatg tagatgtagc acttacttta tggcctaagc gctttgagat
    18961 tgtgctgaca atatataaac caataccgct tgatttctca cttattctac cgttatagcc
    19021 cgagaaacct ttatcaaaga ttttcggtaa atcactcgca ttaatgccga taccgttatc
    19081 tcggattgat aatttctttg tattttcgtc aaacgtaatc cacacatctt tgccacgtgc
    19141 atattttaat gcattgttta atatttgctc aatcataatt gatgcccatt tggcatctgt
    19201 taatataacc gcttcacttt tctcataatg caactttgtt tgatgatgaa taaactgtat
    19261 cgcataacgt ttaatcagtg gtcgaattaa ttcatctaca ctcacttcca taaagaccat
    19321 gtatgtcttt tggttcatga gtttcaaata gttcagtgca agattcgtgt aattatcaat
    19381 ttgtaagact tcattacgca cgttagaaat cacgtgttca tcaggatctt caagcagtaa
    19441 ctttgatgct gtaatcggtg tcttgatttg atgcacccac attaaaaaat atgactctaa
    19501 ctcactttgg tagttaataa agtcattacg aagtttatgg ttttcgattc ttaaatcttc
    19561 gttctgttcc tgtagtgttt attctttttt aaagttcatg taatggatac cccagtaaat
    19621 cattgaaaca aacaatacaa tacctagacc aatcatatat gcttgcatcg gcacattata
    19681 catgaataat ataaagtaga ataaagcaca agtaaggatg acaatataaa tttcacgttg
    19741 gattgatttc aagaaattca tacgtcacct acacgatatc cgacattttt cttcgtttcg
    19801 ataaaatctg taagtcctag tttttgtagc tttttgcgta aacgtgtaat gttgacagca
    19861 agcgtattgt catcaatgaa gtgttctgat tcccagcatt tttcgattaa cgcattacga
    19921 ctgacgaatt tgcccttgtt ctggaataag ctatgcatga tttgcaattc agtgtgtgtc
    19981 aggtctatgg tttcttcatt aaatttaagc tttgctgcat caagtagtaa ctcgcaatca
    20041 tctactgtta aattattaac ttgagtggtg aaatcatacg tgcggcgtaa tagtgcttga
    20101 atcttagtaa ttgtaacagt catattaaat ggctggttct gttgcaaagt aaaaaatata
    20161 gctaatcact aatatatcat gtcagtgttc gtttaacttg ctagcatgat gctaatttcg
    20221 tggcatgggg aaaatccgta gatctgaaga gacctacggt tctttttata tagagcgtaa
    20281 atacattcaa taccttttaa agtattcttt gccgtattga tactttgata tcttgtcttt
    20341 cttactttaa tatgacggtg atcttgctca atgaggttat tcagatattt cgatgtacaa
    20401 tgacagtcag gtttaagttt aaaagcttta attattttag ccattgctgc cttcgttgaa
    20461 ggtgcctgat ctgtaactac cttttgaggc ttaccaaatt gtttaatgag acgtttgata
    20521 aacgcatatg ctgaatgatt atctcgttgc ttacgcaacc aaatatctaa tgtatgtccc
    20581 tctgtatcaa tggcacgata taaatagctc cattttcctt ttattttgat atacgtctca
    20641 tcaatacgcc atttgtaata agctttttta tgctttttct tccaaatttg atataaaatt
    20701 ggggcatatt cttgaaccca acggtagatc gttgaatgat gaacgtttac accacgttct
    20761 cttaatattt cagatatatc acgatagctc aatgcatatc ttagatagta gccaacggct
    20821 acagtgataa catccttgtt aaattgttta tatctgaaat agttcataca gaagactcct
    20881 ttttgttaaa attatattat aaattcaact ttgcaacaga accgtatttt atgagtacac
    20941 tctaaattaa ggagatgtat aatcaatcta aaattgtatt tttatacttt tgttatataa
    21001 tctttctact tagagatata ttgtaaaaaa accaacaaaa tgttatatta acattactat
    21061 tttatcgatg aaggaggatt aaaatgacag cttctatgag actcaaataa acctttttga
    21121 atacaaaact aaattaattc aaaaaggctt gtccgcaata cacactcata ggatgactta
    21181 tgtcattttt tatccttcga taggaataat aaacgctttc aaatactaaa acatcataat
    21241 aaatttttaa gtgtttgaaa gtgtaatgtg aatgagacgg gagtagcctg tctcattttt
    21301 ttgcgtacac gtcctttaaa tatacaagga gtgtataaat atggaacaat atacaattaa
    21361 atttaaccaa atcaatcata aattgacaga tttacgatca cttaacatcg gtcatcttta
    21421 cgcttaccaa tttgaaaaaa tagcacttat tgggggtaat ggtactggca aaaccacatt
    21481 actaaatatg attgctcaaa aaacaaaacc agaatctgga acagttgaaa cggttggcga
    21541 aattcaatat tttgaacagc ttaacatgga tgtggaaaat gattttaaca cgttagacgg
    21601 tagtttaatg agtgaactcc atatacctat gcatacaacc gacagtatga gtggtggtga
    21661 aaaagcaaaa tataaattag ctaatgtcat atcaaattat agtccgatat tacttttaga
    21721 tgaacctaca aatcacttgg ataaaattgg taaagattat ctgaaaaata ttttaaaata
    21781 ttactatggt actttaatta tagtaagtca tgatagagca cttatagacc aaattgctga
    21841 cacaatttgg gatatacaag aagatggcac aataagagtg tttaaaggta attacacaca
    21901 gtatcaaaat caatatgaac aagaacagtt agaacaacaa cgtcaatatg aacagtatat
    21961 aagtgaaaaa caaagattgt cccaagccag taaagctaaa cgaaatcaag cgcaacaaat
    22021 ggcacaagca tcatcaaaac aaaaaaacaa aagtatagca ccagatcgtt taagtgcatc
    22081 aaaacaaaaa ggcacggttg agaaggctgc tcaaaaacaa gctaagcata ttgaaaaaag
    22141 aatggaacat ttggaagaag ttgaaaaacc acaaagttat catgaattca atttcccaca
    22201 aaataaaatt tatgatatcc ataataatta tccaatcatt gcacaaaatc taacattggt
    22261 taaaggaagt caaaaactgc taacacaagt acgattccaa ataccatatg gcaaaaatat
    22321 agcgctcgta ggtgcaaatg gtgtaggtaa gacaacttta cttgaagcta tttaccacca
    22381 aatagaggga attgattgtt ctcctaaagt gcaaatggca tactatcgtc aacttgctta
    22441 tgaagacatg cgtgacgttt cattattgca atatttaatg gatgaaacgg attcatcaga
    22501 atcattcagt agagctattt taaataactt gggtttaaat gaagcacttg atcgttcttg
    22561 taatgttttg agtggtgggg aaagaacgaa attatcgtta gcagtattat tttcaacgaa
    22621 agcgaatatg ttaattttgg atgaaccaac taatttttta gatattaaaa cattagaagc
    22681 attagaaatg tttatgaata aatatcctgg aatcattttg tttacatcac atgatacaag
    22741 gtttgttaaa catgtatcag ataaaaaatg ggaattaaca ggacaatctc ttcatgatat
    22801 aacttaaaaa ctatacacta atttatattg aatattaggt tcatttatat caatataaaa
    22861 aatacgttca caagaaaaat ataatagaaa taaggatcca ataaaatgac tcgacataat
    22921 gaaattatta aatgtgcaga aaaatatcaa ttacacatcc aacctcaaac aatctcattg
    22981 aatgaatcgg gacttgattt tcaagttgca tttggaaaag ataaacatgg agtagaatgg
    23041 gttttgagac taccaagaag acctgacgtt tataaacgaa caaaacccga aaaacaaacg
    23101 gtagacttct tacagaagaa tgtttcattt gaaataccga agtggaaagt acatgcaaaa
    23161 gaccttattg cttacccaaa acttacaggt aaacccgcag ccacaataga tccagaaata
    23221 caaaattatg tatgggaaat tgaacacaaa ccattaccag aaaactttat taacacatta
    23281 gctgaaacac tcgtagattt acacaacata ccagaagaaa acattaacgt tcagcatata
    23341 aatatcaaaa ccatacaaga aataaaaaat gactttcaaa gaagaatgaa taaagttaaa
    23401 gaaacttatg gcgtatcaga tgaattatgg aacagatgga aacaatggtt agaaaacgac
    23461 gaactatggc ctcgacatgc gaccatgata catggggact tacatccagg acatataatg
    23521 gtagataacc aagcaaacgt cacaggtctc atagactgga ctgaagcaac ccactccgac
    23581 ccatcaatgg actttatagg acaccatcgt gtattcgacg acgaaggatt agagcaactt
    23641 ataacagcat acggtaaagc tggaggtgaa atatggccac gaatgaaaga gcatataata
    23701 gaactcaatg cagtattccc aatgtttatc gctgagtttg ctatggaatc aggagaatcg
    23761 gcgtatgaaa cgatggcatt gaaagagtta ggtatgaaag agtagaactt atattaaaag
    23821 aggcccattt taaagacgaa ggcaatcctg atgaaatttt aaaactgcgt ttaattagtg
    23881 atggtctttg gttttctata atgtattaaa tatctggaca tggaacaaat gcaacaaatg
    23941 gaaagaatcg ttttcgaaat ttctaactcc ttaaatcagg aggataaata aacggtcatt
    24001 ttcattgaaa gcacttatat aaatttcatc aattttaata cctaccgtaa atacatttca
    24061 taagtattaa acagatgatt aaaattttta gttaatttaa atatttatga tagagatgac
    24121 cttcaaatga acggttctgt tacaaagaaa aaatctatat ttatttttag taagttttaa
    24181 ttatagatat gtacactttg agtacaccct aaccatacaa aaagaattgt tgaaattata
    24241 acaattaaaa cgtatgatta gggtgtatat ttattatgga gtgaagatga atgattatag
    24301 gttatgcgag agtatcatcg atagatcaaa atttagaaag acaattggat aatttaaaga
    24361 cgtttggtgt ggagaaaatc tttacagaga aacagtcggg aaagtcagtg gaaaatagac
    24421 ctgtatttca agaagcactc aattttgtca gaatgggaga tcgattcgtt gtggaatcta
    24481 ttgatcgttt aggacgtaac tatgatgaaa ttattgaaac tgtgaattat ttaaaagaaa
    24541 aagacgttca gttaatgatt accagcttac ctatgatgaa tgaagtaatt ggcaatccat
    24601 tactggataa gtttatgaaa gatttaatca ttcaaatatt agcaatggtt tcagaacaag
    24661 agagaaatga aagtaaacgt cgacaagcgc aagggattca agttgcgaag gaaaaaggcg
    24721 tatataaagg gcgcccttta ctttattcac caaatgctaa agacccacag aaacgtgtta
    24781 tttatcatcg cgtggtggaa atgttagaag aaggcaaagc gattagtaag attgcgaaag
    24841 aagttaatat cacaagacaa acagtttata gaattaaaca tgataaggga ttatcttgat
    24901 aaattgattg tcaatgcaaa tgagcgtctc tcacagtgtc tcaaattcca taacatatta
    24961 ttgaattgag attttaataa ttatacaaga aaaaagagta cgagttcgca gctttctata
    25021 tagtaattgt tttactaata aggtgtttta aaatatatta taatgtaaaa agtatttgac
    25081 atttgtatca aaaatattta cactcataaa tgtcaaatac tttttacatt tatgaggtgt
    25141 tataatgaat ttaattcctt ttattattat tttaattttt tcttgtttat ggacggctat
    25201 aactaacaaa tatttacctt cagaaacatt agataaaaaa ggacaacaag atcgatacga
    25261 tgaaagacaa cgtaaaatgt ttattgaaat actggctaaa agttttattt ggattgtata
    25321 ttgtatgtta tttacactag tgcttaaatt tacaggtttg tcaccaagta ttgaaggatc
    25381 ttggttttct caatatccag aaattttctt tataattgta gcactatttc ttatgctgtt
    25441 taattactat actacaaata aaaaatatac atctaaaggt taaattaatg aaaaatagaa
    25501 ttagagaata tagaaaacaa aaaggaattt ctcaagaaac tttaagtaaa gaattaaaag
    25561 tgtctaggca aactattaat gcaatagaaa acaataaata tgatcctaca ttgacattag
    25621 catttaagtt ggcaagattg tttgatacaa ctgtggatga attattttct taaccattca
    25681 tttatcacaa aaagagagtg cgaattcgca ctctcttttt gtgtagtagt actattaaat
    25741 tttgtctcaa taacgaacgt ttataacgca atcatgatga gagtattaat acagttaatt
    25801 atttgaaata ctttagttta cataatcgat gattaccaga agttctcact atataaaaga
    25861 cactaaaatt ttataacttt tagtgcctaa tcaattattt tagctaccaa acaaacgact
    25921 ccaaaacccc tttttaggtt ccgtttcttc actcttttct tctatatcac tatcattgtc
    25981 atttagatta gctggaacgt cttctttttt tgcttcttca ccttgtgtac tttcgtcgct
    26041 ttgacttcca gatatatcct tatattgaat ctctgtttct ttagtttctt cctgatctct
    26101 gttaatattt acaggattag tagtatatgt tttttcttgt gcatcaacgt tttgtctagt
    26161 gttagtagat gtatcaaagg gataattaag gtgtttttct ttttctaatt gattttctaa
    26221 tttttgaatc tttttattac tctctaatgc cagaacttgc tgattttcaa gcaattttga
    26281 tctttcttgc aactcttttc tgtaaaattc aattgttgtt tcatgacgac tttcttgttt
    26341 ttcaatttga ttatttaaag tatcaatctg atttttaagg atttctacta tttgagcatc
    26401 gcttttcgat tcaaaattaa tattatccga cccttttttt tgtttgtctt cagtagtact
    26461 ttcaaaacca tatttctttt tattttcatt tactctttga atgatttttt ctatatcggt
    26521 atcttcttta ataaacgaag tgttttcctg ttttattgtc tctatattca atcgcttaat
    26581 attattaaaa atcgtttgct tactaacccc taattcttca ctcaactttt tcacactttt
    26641 catatcatca accctttata aaatgtttat aaacccttga taaaatatta taagcttata
    26701 atgcttaata ataaagtgat taataaataa aaataaacat ccatcaacct ttttatcaag
    26761 ggtttatgaa aggtttatga tatttatcaa gggtttataa acccttgata aagctatatt
    26821 ttccctttta taagtttatt taaagtgcta taataaactt aatataacaa aaaccccaac
    26881 tactggtaat agtcggggtt tggtaataaa acgtttagaa actgtttatt tatataattt
    26941 tcgatacttg tattatataa tgaataatat cttagtgcaa gcacctaaat cattaaataa
    27001 atgtaaagct aaataaaaac gttttattac ctcttaccaa actaaaatat ggaaagaggt
    27061 tttttgtc
//
