LOCUS       NZ_AP027778            26235 bp    DNA     circular CON 04-APR-2024
DEFINITION  Escherichia coli strain 2017.03.04CC plasmid p2017.03.04CC_3,
            complete sequence.
ACCESSION   NZ_AP027778
VERSION     NZ_AP027778.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMD00562590
            Assembly: GCF_036504195.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1
  AUTHORS   Hoang,H.T.T., Yamamoto,M., Calvopina,M., Bastidas-Caldes,C.,
            Khong,D.T., Nguyen,T.N. and Yamamoto,Y.
  TITLE     Comparative genome analysis of colistin-resistant Escherichia coli
            strains possessing mcr isolated in Ecuador and Vietnam
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 26235)
  AUTHORS   Yamamoto,Y. and Hoang,H.T.T.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAR-2023) Contact:Yoshimasa Yamamoto The United
            Graduate School of Drug Discovery and Medical Information Sciences,
            Gifu University; Yanagido 1-1, Gifu 501-1194, Japan
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.8
            Genome Coverage                   :: 83x
            Sequencing Technology :: MGI DNBSEQ-G400RS; ONT MinION Mk1c
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_036504195.1-RS_2024_04_04
            Annotation Date                   :: 04/04/2024 00:15:21
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,598
            CDSs (total)                      :: 4,486
            Genes (coding)                    :: 4,081
            CDSs (with protein)               :: 4,081
            Genes (RNA)                       :: 112
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 83
            ncRNAs                            :: 7
            Pseudo Genes (total)              :: 405
            CDSs (without protein)            :: 405
            Pseudo Genes (ambiguous residues) :: 0 of 405
            Pseudo Genes (frameshifted)       :: 170 of 405
            Pseudo Genes (incomplete)         :: 225 of 405
            Pseudo Genes (internal stop)      :: 49 of 405
            Pseudo Genes (multiple problems)  :: 37 of 405
            Pseudo Genes (short protein)      :: 4 of 405
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AP027778.1.
            Annotated by DFAST https://dfast.ddbj.nig.ac.jp/
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..26235
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="2017.03.04CC"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /plasmid="p2017.03.04CC_3"
                     /geo_loc_name="Viet Nam:Thai Binh"
                     /collection_date="2017"
     gene            23..337
                     /locus_tag="AABJ94_RS22620"
                     /old_locus_tag="VEE53_45230"
     CDS             23..337
                     /locus_tag="AABJ94_RS22620"
                     /old_locus_tag="VEE53_45230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001749965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbM/KikA/MpfK family conjugal transfer protein"
                     /protein_id="WP_000734776.1"
                     /translation="MKKLLIPLIAAGSLLYLPASHAEDPCKVIMCMAGKLTGDSGGSEC
                     NSAEAAFFNIVKKNKHGFLPNHTKDARKAFLNECPDNGEGGSNQSMISQIISKYGKVRL
                     "
                     /name="TrbM/KikA/MpfK family conjugal transfer protein"
     gene            373..684
                     /locus_tag="AABJ94_RS22625"
                     /old_locus_tag="VEE53_45240"
     CDS             373..684
                     /locus_tag="AABJ94_RS22625"
                     /old_locus_tag="VEE53_45240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001452736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001452736.1"
                     /translation="MKKIILSALACTALLTGCVSQDKGNAMQSQLNNQQRQINELSVRL
                     QSAESRLSKQEEKLRNELLQSSGYCYLNGARYSTGTVLYGRICQNQSGSASWQVYSRR"
                     /name="hypothetical protein"
     gene            740..1381
                     /locus_tag="AABJ94_RS22630"
                     /old_locus_tag="VEE53_45250"
     CDS             740..1381
                     /locus_tag="AABJ94_RS22630"
                     /old_locus_tag="VEE53_45250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001749966.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0004519 - endonuclease activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="WP_001694850.1"
                     /translation="MIPFPTTENLILWACSAIVLLAVVFFRRSVRHRRHKRKQQSARRV
                     LERIKTLPGFPQKINYLRKIDPFVFEELLLEGFEAHGFRTIRNKRYTGDGGIDGQVIIG
                     KYRYLIQAKRYRGHIALQHVQEFEKLLKRHNCRGLFCHTGKTGAGSKSVSIASERMEII
                     SGQRLIDLLTPGSSFTIATAPQTMMKRTAATLETSTIVKDAGKENRYHES"
                     /name="restriction endonuclease"
     gene            1386..1583
                     /locus_tag="AABJ94_RS22635"
                     /old_locus_tag="VEE53_45260"
     CDS             1386..1583
                     /locus_tag="AABJ94_RS22635"
                     /old_locus_tag="VEE53_45260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000844102.1"
                     /translation="MKSVTIEAKTFAEMLGITEGELIFAIKKTGTFKNKTIPQPHEPHK
                     SNNRFLYSDVMRFIESLKDK"
                     /name="hypothetical protein"
     gene            complement(1784..2644)
                     /locus_tag="AABJ94_RS22640"
                     /old_locus_tag="VEE53_45270"
     CDS             complement(1784..2644)
                     /locus_tag="AABJ94_RS22640"
                     /old_locus_tag="VEE53_45270"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="broad-spectrum class A beta-lactamase TEM-1"
                     /protein_id="WP_000027057.1"
                     /translation="MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYI
                     ELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYS
                     PVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRW
                     EPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSA
                     LPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGAS
                     LIKHW"
                     /name="broad-spectrum class A beta-lactamase TEM-1"
     gene            complement(2827..3384)
                     /locus_tag="AABJ94_RS22645"
                     /old_locus_tag="VEE53_45280"
     CDS             complement(2827..3384)
                     /locus_tag="AABJ94_RS22645"
                     /old_locus_tag="VEE53_45280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221001.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001235713.1"
                     /translation="MRLFGYARVSTSQQSLDLQVRALKDAGVKANRIFTDKASGSSTDR
                     EGLDLLRMKVEEGDVILVKKLDRLGRDTADMIQLIKEFDAQGVAVRFIDDGISTDGDMG
                     QMVVTILSAVAQAERRRILERTNEGRQEAKLKGIKFGRRRTVDRNVVLTLHQKGTGATE
                     IAHQLSIARSTVYKILEDERAS"
                     /name="recombinase family protein"
     gene            3548..6553
                     /locus_tag="AABJ94_RS22650"
                     /old_locus_tag="VEE53_45290"
     CDS             3548..6553
                     /locus_tag="AABJ94_RS22650"
                     /old_locus_tag="VEE53_45290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495017.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element Tn3 family transposase"
                     /protein_id="WP_001143760.1"
                     /translation="MPVDFLTTEQTESYGRFTGEPDELQLARYFHLDEADKEFIGKSRG
                     DHNRLGIALQIGCVRFLGTFLTDMNHIPSGVRHFTARQLGIRDITVLAEYGQRENTRRE
                     HAALIRQHYQYREFAWPWTFRLTRLLYTRSWISNERPGLLFDLATGWLMQHRIILPGAT
                     TLTRLISEVREKATLRLWNKLALIPSAEQRSQLEMLLGPTDCSRLSLLESLKKGPVTIS
                     GPAFNEAIERWKTLNDFGLHAENLSTLPAVRLKNLARYAGMTSVFNIARMSPQKRMAVL
                     VAFVLAWETLALDDALDVLDAMLAVIIRDARKIGQKKRLRSLKDLDKSALALASACSYL
                     LKEETPDESIRAEVFSYIPRQKLAEIITLVREIARPSDDNFHEEMVEQYGRVRRFLPHL
                     LNTVKFSSAPAGVTTLNACDYLSREFSSRRQFFDDAPTEIISRSWKRLVINKEKHITRR
                     GYTLCFLSKLQDSLRRRDVYVTGSNRWGDPRARLLQGADWQANRIKVYRSLGHPTDPQE
                     AIKSLGHQLDSRYRQVAARLCENEAVELDVSGPKPRLTISPLASLDEPDSLKRLSKMIS
                     DLLPPVDLTELLLEINAHTGFADEFFHASEASARVDDLPVSISAVLMAEACNIGLEPLI
                     RSNVPALTRHRLNWTKANYLRAETITSANARLVDFQATLPLAQIWGGGEVASADGMRFV
                     TPVRTINAGPNRKYFGNNRGITWYNFVSDQYSGFHGIVIPGTLRDSIFVLEGLLEQETG
                     LNPTEIMTDTAGASELVFGLFWLLGYQFSPRLADAGASVFWRMDHDADYGVLNDIARGQ
                     SDPRKIVLQWDEMIRTAGSLKLGKVQVSVLVRSLLKSERPSGLTQAIIEVGRINKTLYL
                     LNYIDDEDYRRRILTQLNRGESRHAVARAICHGQKGEIRKRYTDGQEDQLGTLGLVTNA
                     VVLWNTIYMQAALDHLRAQGETLNDEDIARLSPLCHGHINMLGHYSFTLAELVTKGHLR
                     PLKEASEAENVA"
                     /name="Tn3-like element Tn3 family transposase"
     gene            complement(<6596..7611)
                     /locus_tag="AABJ94_RS22655"
                     /pseudo=""
     CDS             complement(<6596..7611)
                     /locus_tag="AABJ94_RS22655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612175.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /name="IS3 family transposase"
     gene            8006..8662
                     /locus_tag="AABJ94_RS22660"
                     /old_locus_tag="VEE53_45330"
     CDS             8006..8662
                     /locus_tag="AABJ94_RS22660"
                     /old_locus_tag="VEE53_45330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001516695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinolone resistance pentapeptide repeat protein
                     QnrS1"
                     /protein_id="WP_001516695.1"
                     /translation="METYNHTYRHHNFSHKDLSDLTFTACTFIRSDFRRANLRDTTFVN
                     CKFIEQGDIEGCHFDVADLRDASFQQCQLAMANFSNANCYGIEFRACDLKGANFSRTNF
                     AHQVSNRMYFCSAFISGCNLSYANMERVCLEKCELFENRWIGTNLAGASLKESDLSRGV
                     FSEDVWGQFSLQGANLCHAELDGLDPRKVDTSGIKIAAWQQELILEALGIVVYPD"
                     /name="quinolone resistance pentapeptide repeat protein
                     QnrS1"
     gene            complement(8981..>9409)
                     /locus_tag="AABJ94_RS22665"
                     /old_locus_tag="VEE53_45340"
                     /pseudo=""
     CDS             complement(8981..>9409)
                     /locus_tag="AABJ94_RS22665"
                     /old_locus_tag="VEE53_45340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017412822.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /name="recombinase family protein"
     gene            complement(9442..>10008)
                     /locus_tag="AABJ94_RS22670"
                     /old_locus_tag="VEE53_45350"
                     /pseudo=""
     CDS             complement(9442..>10008)
                     /locus_tag="AABJ94_RS22670"
                     /old_locus_tag="VEE53_45350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001493761.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="ISKra4-like element ISKpn19 family transposase"
                     /name="ISKra4-like element ISKpn19 family transposase"
     gene            10071..10775
                     /locus_tag="AABJ94_RS22675"
                     /old_locus_tag="VEE53_45360"
     CDS             10071..10775
                     /locus_tag="AABJ94_RS22675"
                     /old_locus_tag="VEE53_45360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_001067848.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIDATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            <10830..11300
                     /locus_tag="AABJ94_RS22680"
                     /old_locus_tag="VEE53_45370"
                     /pseudo=""
     CDS             <10830..11300
                     /locus_tag="AABJ94_RS22680"
                     /old_locus_tag="VEE53_45370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /name="IS6-like element IS26 family transposase"
     gene            complement(11246..12340)
                     /gene="intI1"
                     /locus_tag="AABJ94_RS22685"
                     /old_locus_tag="VEE53_45380"
     CDS             complement(11246..12340)
                     /gene="intI1"
                     /locus_tag="AABJ94_RS22685"
                     /old_locus_tag="VEE53_45380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1 integron integrase IntI1"
                     /protein_id="WP_338390034.1"
                     /translation="MKTATAPLPPLRSVKVLDQLRERIRYLHYSLRTEQAYVHWVRAFI
                     RFHGVRHPATLGSSEVEAFLSWLANERKVSVSTHRQALAALLFFYGKVLCTDLPWLQEI
                     GRPRPSRRLPVVLTPDEVVRILGFLEGEHRLFAQLLYGTGMRISEGLQLRVKDLDFDHG
                     TIIVREGKGSKDRALMLPESLAPSLREQLSRARAWWLKDQAEGRSGVALPDALERKYPR
                     AGHSWPWFWVFAQHTHSTDPRSGVVRRHHMYDQTFQRAFKRAVEQAGITKPATPHTLRH
                     SFATALLRSGYDIRTVQDLLGHSDVSTTMIYTHVLKVGGAGVRSPLDARHCCKVSDEAA
                     FCLIQRPYISKTLLTRRISPRGSP"
                     /name="intI1"
     gene            12489..13327
                     /gene="aadA1"
                     /locus_tag="AABJ94_RS22690"
                     /old_locus_tag="VEE53_45390"
                     /pseudo=""
     ARG             12490..13277
                     /name="aadA1"
                     /gene="aadA1"
                     /gene_name="ANT(3'')-Ia family aminoglycoside
                     nucleotidyltransferase AadA1"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(13448..14144)
                     /locus_tag="AABJ94_RS22695"
     CDS             complement(join(13448..13892,13891..14144))
                     /locus_tag="AABJ94_RS22695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558260.1"
                     /ribosomal_slippage=""
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1-like element IS1B family transposase"
                     /protein_id="WP_001390281.1"
                     /translation="MASVSISCPSCSATDGVVRNGKSTAGHQRYLCSHCRKTWQLQFTY
                     TASQPGTHQKIIDMAMNGVGCRATARIMGVGLNTIFRHLKKLRPQSVTSRIQPGSDVIV
                     CAEMDEQWGYVGAKSRQRWLFYAYDRLRKTVVAHVFGERTMATLGRLMSLLSPFDVVIW
                     MTDGWPLYESRLKGKLHVISKRYTQRIERHNLNLRQHLARLGRKSLSFSKSVELHDKVI
                     GHYLNIKHYQ"
                     /name="IS1-like element IS1B family transposase"
     gene            complement(14401..>14673)
                     /locus_tag="AABJ94_RS22700"
                     /old_locus_tag="VEE53_45430"
                     /pseudo=""
     CDS             complement(14401..>14673)
                     /locus_tag="AABJ94_RS22700"
                     /old_locus_tag="VEE53_45430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612230.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0004803 - transposase activity [Evidence IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
                     /name="IS1 family transposase"
     gene            14767..16228
                     /locus_tag="AABJ94_RS22705"
                     /old_locus_tag="VEE53_45450"
                     /pseudo=""
     CDS             14767..16228
                     /locus_tag="AABJ94_RS22705"
                     /old_locus_tag="VEE53_45450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288433.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /name="DNA cytosine methyltransferase"
     gene            complement(16230..17439)
                     /locus_tag="AABJ94_RS22710"
                     /pseudo=""
     CDS             complement(16230..17439)
                     /locus_tag="AABJ94_RS22710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_143212653.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="type II site-specific deoxyribonuclease"
                     /name="type II site-specific deoxyribonuclease"
     gene            complement(17530..18233)
                     /locus_tag="AABJ94_RS22715"
                     /pseudo=""
     CDS             complement(17530..18233)
                     /locus_tag="AABJ94_RS22715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /name="IS6-like element IS26 family transposase"
     gene            complement(18270..18590)
                     /locus_tag="AABJ94_RS22720"
     CDS             complement(18270..18590)
                     /locus_tag="AABJ94_RS22720"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_338390033.1"
                     /translation="MIALSIIRLLHYMEQTPDTYSYTACHIGCSSVLVEDSSTPARATN
                     SGLENTKKPDYQSGFFVPVVRLFFRFFPSFGGFFFHFLLRPILLFALANCVMAGTVANS
                     RW"
                     /name="hypothetical protein"
     gene            18571..18654
                     /gene="dinQ"
                     /locus_tag="AABJ94_RS22725"
     CDS             18571..18654
                     /gene="dinQ"
                     /locus_tag="AABJ94_RS22725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165328.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible type I toxin DinQ"
                     /protein_id="WP_000565612.1"
                     /translation="MIDKAIIVLGALISLLELIRYLLQLMG"
                     /name="dinQ"
     gene            complement(18809..19453)
                     /locus_tag="AABJ94_RS22730"
                     /old_locus_tag="VEE53_45500"
     CDS             complement(18809..19453)
                     /locus_tag="AABJ94_RS22730"
                     /old_locus_tag="VEE53_45500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001503708.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000203396.1"
                     /translation="MTSNVPTSFVRAYLRASTAEQDASRALETIEAFARERGLIICSYY
                     IENESGTRLERPELFRLLRDCQQNDILLIEDVDRLSRLSGEDWNTLKKMIRQKDIRVMA
                     VNVPTTWINSGMSEFDSRLFAAINDMLLDMLAAVARRDYEQRRERQKQGIEKAKKDGKY
                     KGRKPNQARHDAIIRLIESGSSWTQVQKVLGCSRGTISNALKRKTGQKSSK"
                     /name="recombinase family protein"
     gene            19834..20496
                     /locus_tag="AABJ94_RS22735"
                     /old_locus_tag="VEE53_45510"
     CDS             19834..20496
                     /locus_tag="AABJ94_RS22735"
                     /old_locus_tag="VEE53_45510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division plane positioning ATPase MipZ"
                     /protein_id="WP_000516402.1"
                     /translation="MGKILLVVSDKGGVGKSTYVANTGSMLVNKGKSVIILKTDKNHDL
                     LSWNEKRTDNGLLTIPVHAAYGNVSNEIKRLSKLCEVLIVDCPGHDSQEFRSALTVSDI
                     VVTLVKPSSDFESETLTSVTEKIRTAQKANAALEPWVLFTRINSAKPRHRKAAIDLDKL
                     LRSDNIWIQPLKTRISELDVYESACNEGAGVHDVSRASSLSTAKAQIELVAQEIGIL"
                     /name="division plane positioning ATPase MipZ"
     gene            20594..20875
                     /locus_tag="AABJ94_RS22740"
                     /old_locus_tag="VEE53_45520"
     CDS             20594..20875
                     /locus_tag="AABJ94_RS22740"
                     /old_locus_tag="VEE53_45520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001185482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001185482.1"
                     /translation="MALKLNRPNIDESQQPATNAETARFISGATRAPVVGKPKLMNFRL
                     SAHFEDILEAEAIRTGQSKTTVLKAALAMYNSQDENIKNHWLLESAKF"
                     /name="hypothetical protein"
     gene            20900..21877
                     /locus_tag="AABJ94_RS22745"
                     /old_locus_tag="VEE53_45530"
     CDS             20900..21877
                     /locus_tag="AABJ94_RS22745"
                     /old_locus_tag="VEE53_45530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6685 family protein"
                     /protein_id="WP_024245156.1"
                     /translation="MRYLTELICDLYRLTDHHKLTTATFKNLADIKLFKPTADADTILQ
                     LENIFSEYSLRYIDKDLAEILSNLITTDKKHSLDFDFNKIQSLTDSKSFGCGWSKVING
                     SWFKDLYSWGEGMYPAENLKAENILDWKDNIWHIEHEGFPPRPPINVKYYSWFDRYVAS
                     NSGGSHHAAMVVYQSVRDGLEYKREAVIKQLSIDPGTVEILDKNYYSFIFQIKTLNKET
                     RIYTSEYEFTDALKDFGQNRHTILKPVNYVSNIKLVFIPKDALKTNSETFRNWFHSAIS
                     CGKIISLPDYLKNPAHYHTLHYSHEVDSITLGDPSRKFKLKGDS"
                     /name="DUF6685 family protein"
     gene            complement(21874..22230)
                     /gene="ddp1"
                     /locus_tag="AABJ94_RS22750"
                     /old_locus_tag="VEE53_45540"
     CDS             complement(21874..22230)
                     /gene="ddp1"
                     /locus_tag="AABJ94_RS22750"
                     /old_locus_tag="VEE53_45540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA distortion polypeptide 3"
                     /protein_id="WP_000456533.1"
                     /translation="MEYQVREFINEKYTKAVNILKDNLKENYHVFYGVRLIEILFPASE
                     YGTDAFFKEFELINSVILPLVIFDLTQRKPMMIISFDKILDASLLEGTNIVVLECITLA
                     DLLTNDNIDFLYKS"
                     /name="ddp1"
     gene            complement(22367..22813)
                     /locus_tag="AABJ94_RS22755"
                     /pseudo=""
     CDS             complement(22367..22813)
                     /locus_tag="AABJ94_RS22755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001074384.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            complement(22853..23689)
                     /locus_tag="AABJ94_RS22760"
                     /old_locus_tag="VEE53_45570"
     CDS             complement(22853..23689)
                     /locus_tag="AABJ94_RS22760"
                     /old_locus_tag="VEE53_45570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050932.1"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="WP_001050931.1"
                     /translation="MNLLSVTKKTKIRHRNEINSTFSSLPLSARRILFMAMAQIDSREE
                     LSEGATFRITAREYAFIADIDVTGAYRQLKEGAEELQASVIRIPRNQLLTPQGNQSSGH
                     TKKRGKLPSDAVRLMNLTAFCDYVESEGYIDIAFSHVIEPYITMLKDSYTTQVLISSVR
                     LADQNSNMLYQFIRKQYSSGKKTFFDIEVDVLKDELELFRIDNGEKVYLYQNFKDFNKV
                     FLQKNIEKINQYTEINHLEVKIVERVARRASKLRFSYKIDKESEGLDIRIPYGFRG"
                     /name="RepB family plasmid replication initiator protein"
     gene            24923..25174
                     /locus_tag="AABJ94_RS22765"
                     /old_locus_tag="VEE53_45580"
     CDS             24923..25174
                     /locus_tag="AABJ94_RS22765"
                     /old_locus_tag="VEE53_45580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000121741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stabilization protein"
                     /protein_id="WP_000121743.1"
                     /translation="MSYQILTTTAASITDLKKNPMGTVAEGEGDAVAILNRNEPAFYCV
                     PPKLYAYYRELAEDAELNAVADERMKNPEIVKVNLDDL"
                     /name="plasmid stabilization protein"
     gene            25164..25445
                     /locus_tag="AABJ94_RS22770"
                     /old_locus_tag="VEE53_45590"
     CDS             25164..25445
                     /locus_tag="AABJ94_RS22770"
                     /old_locus_tag="VEE53_45590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001694627.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_000220560.1"
                     /translation="MTYELAFDRRALKEWQKLGHTIREQFKKKLAERLENPRVPAARLH
                     GHADRYKIKLRASGYRLVYQVIDEKVVLLVIAVGRRESSEVYQIADLR"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            25520..26217
                     /locus_tag="AABJ94_RS22775"
                     /old_locus_tag="VEE53_45610"
     CDS             join(25520..25769,25769..26217)
                     /locus_tag="AABJ94_RS22775"
                     /old_locus_tag="VEE53_45610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001743396.1"
                     /ribosomal_slippage=""
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1-like element IS1A family transposase"
                     /protein_id="WP_103215986.1"
                     /translation="MASVSISCPSCSATDGVVRNGKSTAGHQRYLCSHCRKTWQLQFTY
                     TASQPGTHQKIIDMAMNGVGCRATARIMGVGLNTILRHFKKLRPQSVTSRIQPGSDVIV
                     CAEMDEQWGYVGAKSRQRWLFYAYDRLRKTVVAHVFGERTMATLGRLMSLLSPFDVVIW
                     MTDGWPLYESRLKGKLHVISKRYTQRIERHNLNLRQHLARLGRKSLSFSKSVELHDKVI
                     GHYLNIKHYQ"
                     /name="IS1-like element IS1A family transposase"
     ARG             8007..8659
                     /name="qnrS1"
                     /gene="qnrS1"
                     /gene_name="quinolone resistance pentapeptide repeat
                     protein QnrS1"
                     /tool="amrfinderplus"
                     /drug_class="QUINOLONE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(1788..2644)
                     /name="blaTEM-1"
                     /gene="blaTEM-1"
                     /gene_name="broad-spectrum class A beta-lactamase TEM-1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             12376..13280
                     /name="aadA"
                     /gene="aadA"
                     /gene_name="ANT(3'')"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="99.62"
                     /coverage="114.45"
     Typing          complement(22368..22813)
                     /name="IncX1"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="98.21"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 aacaaactgt taaggacaaa aaatgaagaa actcttaata cctctgatag cagctggtag
       61 tctgctttat cttcctgcca gccatgctga agatccctgc aaagttatta tgtgcatggc
      121 gggcaagctc accggcgata gcggcggaag cgagtgtaac agtgctgaag ctgctttctt
      181 caatatcgtt aaaaagaaca agcacggctt tttacccaac cacacgaagg atgctaggaa
      241 ggcttttctt aatgaatgcc cggataatgg cgaaggtgga agtaaccagt cgatgataag
      301 ccagatcata agtaaatacg ggaaagttcg cttataggcg aaccaggaat aatctcaatt
      361 taaggagcca acgtgaaaaa aataatatta agtgcattag cctgtacagc tctcttaact
      421 ggttgcgtca gccaggataa aggtaatgcg atgcagagcc agctgaataa ccagcaacgc
      481 cagattaacg aattatccgt tcgtttgcag tctgcggagt cccggctatc aaagcaggaa
      541 gaaaagctgc gcaacgaact gctgcaatcc agcggctatt gctatctgaa tggcgcccgc
      601 tactcgaccg gcaccgtact ttacgggcgg atttgccaga atcagtcagg cagcgcttcg
      661 tggcaggtat acagccgtcg ctaaacatca gggcggttta accgcccttt tctttaccct
      721 cagaaagccc actataacca tgatcccctt ccccactaca gaaaacctta ttctatgggc
      781 ttgcagcgcc atcgtactgc ttgccgttgt attcttccgg cgttcagtac ggcacaggcg
      841 acacaaaagg aagcagcaaa gtgcgcggcg ggtgctggag cgcataaaga cgttgccggg
      901 cttcccacaa aaaattaact acctgagaaa aattgatcct tttgtgtttg aagaactgtt
      961 gctggaagga tttgaagcgc atggcttcag aaccatcaga aacaaacgct ataccggcga
     1021 tggaggcatt gacggccagg taataatagg aaaatatcgc tatcttattc aggctaaacg
     1081 ctatcgcggc catattgctt tacagcacgt acaggagttc gagaagttgc ttaaacgtca
     1141 taactgtcgc ggtctgtttt gccataccgg gaaaaccggc gcaggttcaa aatctgtcag
     1201 tattgccagt gaacggatgg agattatcag cggccagcgc ctgatagatt tgctcacgcc
     1261 cggtagctcc ttcactatcg caaccgcccc gcagacgatg atgaagcgta ccgcagcaac
     1321 gctagaaacg agcaccattg ttaaagatgc cggtaaagaa aatcgatacc atgagagtta
     1381 attaaatgaa gtcagtaact atagaagcaa aaacatttgc tgaaatgtta ggaataacag
     1441 aaggtgagtt aatctttgcc attaagaaaa ctggcacatt caaaaacaag acaatcccac
     1501 aacctcatga gccacataaa tcaaataata gatttttata ttcagacgta atgaggttta
     1561 tagaatcact aaaagacaaa tagaaccggt aaggcactgt tgcaaagtta gcgatgaggc
     1621 agccttttgt cttattgggg tctgacgctc agtggaacga aaactcacgt taagggattt
     1681 tggtcatgag attatcaaaa aggatcttca cctagatcct tttaaattaa aaatgaagtt
     1741 ttaaatcaat ctaaagtata tatgagtaaa cttggtctga cagttaccaa tgcttaatca
     1801 gtgaggcacc tatctcagcg atctgtctat ttcgttcatc catagttgcc tgactccccg
     1861 tcgtgtagat aactacgata cgggagggct taccatctgg ccccagtgct gcaatgatac
     1921 cgcgagaccc acgctcaccg gctccagatt tatcagcaat aaaccagcca gccggaaggg
     1981 ccgagcgcag aagtggtcct gcaactttat ccgcctccat ccagtctatt aattgttgcc
     2041 gggaagctag agtaagtagt tcgccagtta atagtttgcg caacgttgtt gccattgctg
     2101 caggcatcgt ggtgtcacgc tcgtcgtttg gtatggcttc attcagctcc ggttcccaac
     2161 gatcaaggcg agttacatga tcccccatgt tgtgcaaaaa agcggttagc tccttcggtc
     2221 ctccgatcgt tgtcagaagt aagttggcag cagtgttatc actcatggtt atggcagcac
     2281 tgcataattc tcttactgtc atgccatccg taagatgctt ttctgtgact ggtgagtact
     2341 caaccaagtc attctgagaa tagtgtatgc ggcgaccgag ttgctcttgc ccggcgtcaa
     2401 cacgggataa taccgcacca catagcagaa ctttaaaagt gctcatcatt ggaaaacgtt
     2461 cttcggggcg aaaactctca aggatcttac cgctgttgag atccagttcg atgtaaccca
     2521 ctcgtgcacc caactgatct tcagcatctt ttactttcac cagcgtttct gggtgagcaa
     2581 aaacaggaag gcaaaatgcc gcaaaaaagg gaataagggc gacacgaaaa tgttgaatac
     2641 tcatactctt cctttttcaa tattattgaa gcatttacca gggttattgt ctcatgagcg
     2701 gatacatatt tgaatgtatt tagaaaaata aacaaatagg ggttccgcgc acatttcccc
     2761 gaaaagtgcc acctgacgtc taagaaacca ttattatcat gacattaacc tataaaaata
     2821 ggcgtatcac gaggcccttt cgtcttcaag aattttataa accgtggagc gggcaatact
     2881 gagctgatga gcaatttccg ttgcaccagt gcccttctga tgaagcgtca gcacgacgtt
     2941 cctgtccacg gtacgcctgc ggccaaattt gattcctttc agctttgctt cctgtcggcc
     3001 ctcattcgtg cgttctagga tcctccggcg ttcagcctgt gccacagccg acaggatggt
     3061 gaccaccatt tgccccatat caccgtcggt actgatcccg tcatcaatga accggactgc
     3121 cacgccctga gcgtcaaatt cctttatcag ttggatcata tcggcagtgt cgcggccaag
     3181 acggtcgagc ttcttaacca gaatgacatc accttcctcc accttcatcc tcagcaaatc
     3241 cagcccttcc cggtctgttg aactgccgga tgccttatcg gtaaatatac ggtttgcttt
     3301 cacacctgcg tctttgagtg ctctgacctg aagatcaaga gactgctgac tggttgagac
     3361 ccgagcgtaa ccaaaaagtc gcataaaaat gtaccttaaa tcgaatatcg gacaactcat
     3421 gtctattatt acaaatttac gatttaatag acatattaat gtaacagttt tacgatgtcc
     3481 gataatttat aacatttcgt acggttggaa aaatgttact aaatgcccgt caggcaggga
     3541 ggccgatatg cccgttgact ttctgaccac tgagcagact gaaagctatg gcagattcac
     3601 cggtgaaccg gatgagcttc agctggcacg atattttcac cttgatgaag cagacaagga
     3661 atttatcgga aaaagcagag gtgatcacaa ccgtctgggc attgccctgc aaattggatg
     3721 tgtccgtttt ctgggcacct tcctcaccga tatgaatcat attccttccg gcgtccggca
     3781 ttttaccgcc agacagctcg ggattcgtga tatcaccgtt cttgcagaat acggtcagag
     3841 ggaaaatacc cgccgtgagc atgcagcgct gatacgtcag cactatcagt atcgtgaatt
     3901 tgcctggccc tggacatttc gccttacccg tcttttatat acccggagct ggataagcaa
     3961 cgaacgtcct ggcctgcttt tcgatctggc gacagggtgg cttatgcaac atcgtattat
     4021 tctccccgga gccactacgc tgacccggtt gatttcagag gtaagggaaa aggcgacgtt
     4081 gcgcctgtgg aacaaactgg cactgatacc gtcagccgaa cagcgttcac agctggagat
     4141 gctgctgggg ccaactgatt gcagccgcct gtctttactg gaatcactga aaaagggccc
     4201 tgtgaccatc agtggtccgg cgtttaatga agcaattgaa cgctggaaaa ctctgaacga
     4261 ttttggcctg catgctgaaa acctgagtac actcccggct gtgcgcctga aaaatctcgc
     4321 acgttatgct ggtatgactt cggtgttcaa tattgccagg atgtcaccgc agaaaaggat
     4381 ggcggttctg gttgcctttg tccttgcatg ggaaacgctg gcgctggatg atgcattgga
     4441 cgttctggac gccatgctgg ccgttatcat ccgtgacgcc agaaagattg ggcagaaaaa
     4501 acggctccgc tcgctgaagg atctggataa atctgcattg gcgctcgcca gcgcatgttc
     4561 gtacctgctg aaagaagaaa caccggacga atcgattcgt gctgaggtgt tcagctacat
     4621 cccaaggcaa aagctggctg aaatcatcac gcttgtccgt gaaattgccc ggccctcaga
     4681 cgataatttt catgaagaaa tggtggagca gtacgggcgc gttcgtcgtt tcctgcccca
     4741 tctgctgaat accgttaaat tttcatccgc acctgccggg gttaccactc tgaatgcctg
     4801 tgactacctc agccgggagt tcagctcacg gcggcagttt tttgacgacg caccaacgga
     4861 aattatcagt cggtcatgga aacggctggt gattaacaag gaaaaacata tcacccgcag
     4921 gggatacacg ctctgctttc tcagtaaact gcaggatagt ctgaggcgga gggatgtcta
     4981 cgttaccggc agtaaccggt ggggagatcc tcgtgcaaga ttactacagg gtgctgactg
     5041 gcaggcaaac cggattaagg tttatcgttc tttggggcac ccgacagacc cgcaggaagc
     5101 aataaaatct ctgggtcatc agcttgatag tcgttacaga caggttgctg cacgtctttg
     5161 cgaaaatgag gctgtcgaac tcgatgtttc tggcccgaag ccccggttga caatttctcc
     5221 cctcgccagt cttgatgagc cggacagtct gaaacgactg agcaaaatga tcagtgatct
     5281 actccctccg gtggatttaa cggagttgct gctcgaaatt aacgcccata ccggatttgc
     5341 tgatgagttt ttccatgcta gtgaagccag tgccagagtt gatgatctgc ccgtcagcat
     5401 cagcgccgtg ctgatggctg aagcctgcaa tatcggtctg gaaccactga tcagatcaaa
     5461 tgttcctgca ctgacccgac accggctgaa ctggacaaaa gcgaactatc tgcgggctga
     5521 aactatcacc agcgctaatg ccagactggt tgattttcag gcaacgctgc cactggcaca
     5581 gatatggggt ggaggagaag tggcatctgc agatggaatg cgctttgtta cgccagtcag
     5641 aacaatcaat gccggaccga accgcaaata ctttggtaat aacagaggga tcacctggta
     5701 caactttgtg tccgatcagt attccggctt tcatggcatc gttataccgg ggacgctgag
     5761 ggactctatc tttgtgctgg aaggtcttct ggaacaggag accgggctga atccaaccga
     5821 aattatgacc gatacagcag gtgccagcga acttgtcttt ggccttttct ggctgctggg
     5881 ataccagttt tctccacgcc tggctgatgc cggtgcttcg gttttctggc gaatggacca
     5941 tgatgccgac tatggcgtgc tgaatgatat tgccagaggg caatcagatc cccgaaaaat
     6001 agtccttcag tgggacgaaa tgatccggac cgctggctcc ctgaagctgg gcaaagtaca
     6061 ggtttcagtg ctggtccgtt cattgctgaa aagtgaacgt ccttccggac tgactcaggc
     6121 aatcattgaa gtggggcgca tcaacaaaac gctgtatctg cttaattata ttgatgatga
     6181 agattaccgc cggcgcattc tgacccagct taatcgggga gaaagtcgcc atgccgttgc
     6241 cagagccatc tgtcacggtc aaaaaggtga gataagaaaa cgatataccg acggtcagga
     6301 agatcaactg ggcacactgg ggctggtcac taacgccgtc gtgttatgga acactattta
     6361 tatgcaggca gccctggatc atctccgggc gcagggtgaa acactgaatg atgaagatat
     6421 cgcacgcctc tccccgcttt gccacggaca tatcaatatg ctcggccatt attccttcac
     6481 gctggcagaa ctggtgacca aaggacatct gagaccatta aaagaggcgt cagaggcaga
     6541 aaacgttgct taacgtgagt tttcgttcca ctgagcgtca gacccctaaa atcctgatgc
     6601 tgatgtagtc ccgttttatc gtcatcacga agctttctgc tatgccattg ctttccgggc
     6661 ttcgcactgc tgtcgtacaa ggctccagtc ccagcaaccg ggcgaacgcc ggcactgttg
     6721 gcaactgcct tccgaagcgt ttttccaccg cacccagcat gacatcctgc accgtttctt
     6781 tgtcatagcc tccggtgctc gctgcccagt caatgatctc cctgtcgcag cagtcctgcg
     6841 cgaaggtcac ccgcagcttt tcgccattat cacagcggaa ctcaaagcca tctgagcacc
     6901 agcgccggtt actttccgct actgctacgc gccccttatg ggcccgctta cggcaaggat
     6961 cagcgggttt acgttcaaga agcagattat gcgttctcat aatgcgatac acccgctttg
     7021 cattaaccac aggcaggccg tcccgctccg actcccgtcg cagcagcgcc cacacacggc
     7081 gataaccata cgtcggcagg tcagccaccg ccatgtttat ccgggacaat acggtggtat
     7141 cgtcagaacg gggctgccgt ctgcgatcct gtcagtcaga tggccggtga acccgaatgc
     7201 tcaactgcgc acgcgacacg ccaagacttc tgcaaacgtc gcttattcgt cgttcccagg
     7261 caacgagggc gcatgcgcaa tccatttttt tgcccggccg aactccacgg cctctttgag
     7321 tatctcggct tccatcgtct ttttgcccag aaggcgctgg agttcgcgaa tttgcttatt
     7381 ggcggcagcg agttcggagg ccggcaccac ttcctcgccc gatgcaacag ccgtcagtga
     7441 accgtcttaa tattgcttgc gccatttgaa tatctggttt gcattgatgc catgcaggcg
     7501 cgcgacatga gacacggtca taccgggctc catagtctgc tgaataatgg caattttttc
     7561 ctgcggtgta cgacgccgac gccgctcagg tcctgataac acttcaacca tcttatcgtt
     7621 ctgactggta ttaaacatag ttccaagact acctcttatt ttaagagagt cgaagtgtct
     7681 ggtgatctat ggggccagtc tagccctctt ccaagtgtag ggagatatag tcaaagtttg
     7741 cttctccgcc gatgagtccg ccctgcgtcg gatagtccga ttttttaccg gcgaagcacg
     7801 gctctcctaa ccctatctaa agcgaataac ttttttcaac agggccgcgt gccaatgcaa
     7861 gagcgatagg cgctctacgc gccaatttga ccacttaaaa caggtaaatt gaggggttgt
     7921 aatgtgttga tgtaacaggc ttttatttta atgtcttggc atatgtataa tggtagtcta
     7981 gccctccttt caacaaggag tactcatgga aacctacaat catacatatc ggcaccacaa
     8041 cttttcacat aaagacttaa gtgatctcac cttcaccgct tgcacattca ttcgcagcga
     8101 ctttcgacgt gctaacttgc gtgatacgac attcgtcaac tgcaagttca ttgaacaggg
     8161 tgatatcgaa ggctgccact ttgatgtcgc agatcttcgt gatgcaagtt tccaacaatg
     8221 ccaacttgcg atggcaaact tcagtaatgc caattgctac ggtatagagt tccgtgcgtg
     8281 tgatttaaaa ggtgccaact tttcccgaac aaactttgcc catcaagtga gtaatcgtat
     8341 gtacttttgc tcagcattta tttctggatg taatctttcc tatgccaata tggagagggt
     8401 ttgtttagaa aaatgtgagt tgtttgaaaa tcgctggata ggaacgaacc tagcgggtgc
     8461 atcactgaaa gagtcagact taagtcgagg tgttttttcc gaagatgtct gggggcaatt
     8521 tagcctacag ggtgccaatt tatgccacgc cgaactcgac ggtttagatc cccgcaaagt
     8581 cgatacatca ggtatcaaaa ttgcagcctg gcagcaagaa ctgattctcg aagcactggg
     8641 tattgttgtt tatcctgact aattgctttg atgtgtgatt ttaaacgctc aaatttataa
     8701 aacgaataat attgtcaacc ttgcaataat agacataggg acaaccatgt ataaattttt
     8761 accctcaggc gtcttcacaa tagagccata tagcagtggg tcacttagtg ggcttaattt
     8821 ttccattaaa gataatatta atattgctca gtataaaaca tcatatggta gcccatcttg
     8881 gcaagtaaac ataaggctgc catttataag gcactgttgc aaaaatgtgg aggtgatagg
     8941 ggtactacgc cggaacccca gatttttccg tccgttcaaa ttatccacgg ttgagcagct
     9001 tgatcccgtc cgcccgcagt tgaccaacag gggaaatatg cctgtacaaa gtttgccggg
     9061 ttatcccaag ttcctggcat agcgtactga cctttgtttc tgattgtccc attgatgcca
     9121 ttgccagtcg cagtttgact ggcgtcattt tataaggtcg gccgccgttc cgcccacggg
     9181 ctcttgctga tgccagacct gcagtcgttc tttcagcaat cagttcgcgc tcaaactccg
     9241 ccagtgcggc aaagataccg aagacaagct tgccagcggc cgttgttgtg tcgatagtcg
     9301 ccccgtgacc ggtcagcact ttcagaccgg tccccctcgc ggtcaggtcg tgcactgtat
     9361 taatgagatg acgaagatca cgaccgaggc ggtccagctt ccatacgacc gagagcataa
     9421 aaaatattgg ggcagcgtga gctatgctgc catcgctggt cccttcccgt cactttgaaa
     9481 acccggatac cagcagacaa atttatcctg cagttcgtta ttcaaaacgg cggtccgggt
     9541 ctgtaacaaa taatgagccc cttttctgct ccactgcatc tgctgctttt tggccattcg
     9601 tctggcgatc acttcattga tcgtggattc cacaaacgcg gttgataccg gctctccgta
     9661 ccgacgcatt tcgccgtagt ttgggatcat catcttatta ttccggatgt aggtatacat
     9721 ttcatccaga tgtttttgca gggatttcag gctaggatag ctgagttcag ggtcatcgca
     9781 atacataacg caattatcaa tatgttccag cgcagcgaca acattgccat gccagagata
     9841 tcgtttaatg ctttccagca gtgccagaac tttactcccc gcctctggat ctgataccag
     9901 cagtccccgg gcatattgca tgagcacctt cagcctcatg gtgatatgaa accagtccag
     9961 cacatgcgtt gactcagggt acataccgaa ctggaggtcc ctgagatggc actgttgcaa
    10021 atagtcggtg gtgataaact tatcatcccc ttttgctgat ggagctgcac atgaacccat
    10081 tcaaaggccg gcattttcag cgtgacatca ttctgtgggc cgtacgctgg tactgcaaat
    10141 acggcatcag ttaccgtgag ctgcaggaga tgctggctga acgcggagtg aatgtcgatc
    10201 actccacgat ttaccgctgg gttcagcgtt atgcgcctga aatggaaaaa cggctgcgct
    10261 ggtactggcg taacccttcc gatctttgcc cgtggcacat ggatgaaacc tacgtgaagg
    10321 tcaatggccg ctgggcgtat ctgtaccggg ccgtcgacag ccggggccgc actgtcgatt
    10381 tttatctctc ctcccgtcgt aacagcaaag ctgcataccg gtttctgggt aaaatcctca
    10441 acaacgtgaa gaagtggcag atcccgcgat tcatcaacac ggataaagcg cccgcctatg
    10501 gtcgcgcgct tgctctgctc aaacgcgaag gccggtgccc gtctgacgtt gaacaccgac
    10561 agattaagta ccggaacaac gtgattgaat gcgatcatgg caaactgaaa cggataatcg
    10621 acgccacgct gggatttaaa tccatgaaga cggcttacgc caccatcaaa ggtattgagg
    10681 tgatgcgtgc actacgcaaa ggccaggcct cagcatttta ttatggtgat cccctgggcg
    10741 aaatgcgcct ggtaagcaga gtttttgaaa tgtaaggcct ttgaataaga caaaaggctg
    10801 cctcatcgct aactttgcaa cagtgccatg aaacctacgt gaaggtcaat ggccgctggg
    10861 cgtatctgta ccgggccgtc gacagccggg gccgcactgt cgatttttat ctctcctccc
    10921 gtcgtaacag caaagctgca taccggtttc tgggtaaaat cctcaacaac gtgaagaagt
    10981 ggcagatccc gcgattcatc aacacggata aagcgcccgc ctatggtcgc gcgcttgctc
    11041 tgctcaaacg cgaaggccgg tgcccgtctg acgttgaaca ccgacagatt aagtaccgga
    11101 acaacgtgat tgaatgcgat catggcaaac tgaaacggat aatcggcgcc acgctgggat
    11161 ttaaatccat gaagacggct tacgccacca tcaaaggtat tgaggtgatg cgtgcactac
    11221 gcaaaggcca ggcctcagca ttttattatg gtgatcccct gggcgaaatg cgcctggtaa
    11281 gcagagtttt tgaaatgtaa ggcctttgaa taagacaaaa ggctgcctca tcgctaactt
    11341 tgcaacagtg ccgcgcatca agcggtgagc gcactccggc accgccaact ttcagcacat
    11401 gcgtgtaaat catcgtcgta gagacgtcgg aatggccgag cagatcctgc acggttcgaa
    11461 tgtcgtaacc gctgcggagc aaggccgtcg cgaacgagtg gcggagggtg tgcggtgtgg
    11521 cgggcttcgt gatgcctgct tgttctacgg cacgtttgaa ggcgcgctga aaggtctggt
    11581 catacatgtg atggcgacgc acgacaccgc tccgtggatc ggtcgaatgc gtgtgctgcg
    11641 caaaaaccca gaaccacggc caggaatgcc cggcgcgcgg atacttccgc tcaagggcgt
    11701 cgggaagcgc aacgccgctg cggccctcgg cctggtcctt cagccaccat gcccgtgcac
    11761 gcgacagctg ctcgcgcagg ctgggtgcca agctctcggg taacatcaag gcccgatcct
    11821 tggagccctt gccctcccgc acgatgatcg tgccgtgatc gaaatccaga tccttgaccc
    11881 gcagttgcaa accctcactg atccgcatgc ccgttccata cagaagctgg gcgaacaaac
    11941 gatgctcgcc ttccagaaaa ccgaggatgc gaaccacttc atccggggtc agcaccaccg
    12001 gcaagcgccg cgacggccga ggtcttccga tctcctgaag ccagggcaga tccgtgcaca
    12061 gcaccttgcc gtagaagaac agcaaggccg ccaatgcctg acgatgcgtg gagaccgaaa
    12121 ccttgcgctc gttcgccagc caggacagaa atgcctcgac ttcgctgctg cccaaggttg
    12181 ccgggtgacg cacaccgtgg aaacggatga aggcacgaac ccagtggaca taagcctgtt
    12241 cggttcgtaa gctgtaatgc aagtagcgta tgcgctcacg caactggtcc agaaccttga
    12301 ccgaacgcag cggtggtaac ggcgcagtgg cggttttcat ggcttgttat gactgttttt
    12361 ttggggtaca gtctatgcct cgggcatcca agcagcaagc gcgttacgcc gtgggtcgat
    12421 gtttgatgtt atggagcagc aacgatgtta cgcagcaggg cagtcgccct aaaacaaagt
    12481 taaacatcat gagggaagcg gtgatcgccg aagtatcgac tcaactatca gaggtagttg
    12541 gcgtcatcga gcgccatctc gaaccgacgt tgctggccgt acatttgtac ggctccgcag
    12601 tggatggcgg cctgaagcca cacagtgata ttgatttgct ggttacggtg accgtaaggc
    12661 ttgatgaaac aacgcggcga gctttgatca acgacctttt ggaaacttcg gcttcccctg
    12721 gagagagcga gattctccgc gctgtagaag tcaccattgt tgtgcacgac gacatcattc
    12781 cgtggcgtta tccagctaag cgcgaactgc aatttggaga atggcagcgc aatgacattc
    12841 ttgcaggtat cttcgagcca gccacgatcg acattgatct ggctatcttg ctgacaaaag
    12901 caagagaaca tagcgttgcc ttggtaggtc cagcggcgga ggaactcttt gatccggttc
    12961 ctgaacagga tctatttgag gcgctaaatg aaaccttaac gctatggaac tcgccgcccg
    13021 actgggctgg cgatgagcga aatgtagtgc ttacgttgtc ccgcatttgg tacagcgcag
    13081 taaccggcaa aatcgcgccg aaggatgtcg ctgccgactg ggcaatggag cgcctgccgg
    13141 cccagtatca gcccgtcata cttgaagcta gacaggctta tcttggacaa gaagaagatc
    13201 gcttggcctc gcgcgcagat cagttggaag aatttgtcca ctacgtgaaa ggcgagatca
    13261 ccaaggtaat cggcaaataa tgtctaacaa ttcgttcaag ccgacgccgc ttcgcggcgc
    13321 ggcttaactc aagcgttaga tgcactaagc acataattgc tcacagccaa actatcaggt
    13381 caagtctgct tttattattt ttaagcgtgc ataataagcc ctacacaaat tgggtaatga
    13441 ctccaactta ttgatagtgt tttatgttca gataatgccc gatgactttg tcatgcagct
    13501 ccaccgattt tgagaacgac agcgacttcc gtcccagccg tgccaggtgc tgcctcagat
    13561 tcaggttatg ccgctcaatt cgctgcgtat atcgcttgct gattacgtgc agctttccct
    13621 tcaggcggga ttcatacagc ggccagccat ccgtcatcca tatcaccacg tcaaagggtg
    13681 acagcaggct cataagacgc cccagcgtcg ccatagtgcg ttcaccgaat acgtgcgcaa
    13741 caaccgtctt ccggagcctg tcatacgcgt aaaacagcca gcgctggcgc gatttagccc
    13801 cgacgtatcc ccactgttcg tccatttccg cgcagacgat gacgtcactg cccggctgta
    13861 tgcgcgaggt taccgactgc ggcctgagtt tttaaatggc ggaaaatcgt gttgaggcca
    13921 acgcccataa tgcgggcggt tgcccggcat ccaacgccat tcatggccat atcaatgatt
    13981 ttctggtgcg taccgggttg agaagcggtg taagtgaact gcagttgcca tgttttacgg
    14041 cagtgagagc agagatagcg ctgatgtccg gcggtgcttt tgccgttacg caccaccccg
    14101 tcagtagctg aacaggaggg acagctgata gaaacagaag ccactggagc acctcaaaaa
    14161 caccatcata cactaaatca gtaagttggc agcatcacct agaagcaaaa acatttgctg
    14221 aaatgttagg aataacagaa ggtgagttaa tctttgccat taagaaaact ggcacattca
    14281 aaaacaagac aatcccacaa cctcatgagc cacataaatc aaataataga tttttatatt
    14341 cagacgtaat gaggtttata gaatcactaa aagacaaata gaaccggtaa tgactccaac
    14401 ttactgatag tgttttatgt tcaaataatg cccgatgacc ttgtcatgca actccaccga
    14461 ttttgagaac gacagtgact tccgtcccag ccttgccaga tgttgtctca gattcaggtt
    14521 atgtcgctca atgcgctgag tgtaacgctt gctgataacg tgcagctttc ccttcaggcg
    14581 ggattcatac agcggccagc catccgtcat ccataccacg acctcaaagg ccgacagcag
    14641 gcccagaaga cgctccagcg tggccaacgt gcgttaccta aaacctgttt aaatatccag
    14701 ataaaaacat tcaatctggg tcaaatgagt gatacagttt cacccataag acccaatgga
    14761 ggcaatatgt ctgaatttga attactggcg caggatctgc ttgagaaagc agaagcggaa
    14821 gaacaactgc gacaggaaaa tgataaaaag ctgctcgggc aggtgctgga aatctatgac
    14881 cagaagtacg tggctgaact gcttagaaaa gttggtaaaa atgagtggag tcgcgagact
    14941 cttaatcgct ggattaatgg taagtgctca cctaagacgc tgacgtcagc cgaagaggaa
    15001 cttctacgaa aaatgcttcc ggaagcgcct gcacatcacc ctaactatgc cttccggttt
    15061 attgacctgt ttgctgggat tggaggtata cggaagggct tcgaaaccat cggtggccag
    15121 tgcgttttta ccagtgaatg gaataaagag gctgtgcgca catataaagc taactggttt
    15181 aacgatgctc aggaacacac tttcaatctc gatattcggg aagtcacgct cagtgataaa
    15241 cctgaagtac ctgaaaacga cgatgcctta cattaatgag catgtgccgg atcatgatgt
    15301 acttctagca ggtttcccct gtcaaccgtt cagccttgcg ggcgtaagca agaaaaactc
    15361 gctcgggcgc gcgcatggtt tcgaatgtga ggctcaggga acacttttct tcgatgtggc
    15421 gcgtattatc cgcgcaaaaa aacctgccat ctttgttctt gaaaacgtta aaaacctgaa
    15481 gagccatgac aagggtaaaa cctttaaagt catcatggat accctcgacg aactgggcta
    15541 tgaagttgcg gatgcagctg agatgggcaa aaacgatcct aaagttatcg acggaaagca
    15601 ctttttacct cagcaccgag aacgtatcgt tttggtcggt ttccgtcgtg atctgaacat
    15661 tcaccagggc tttaccctgc gcgatattag tcgtttttat ccggaacagc gtccgtcatt
    15721 tggcgaactg ctggaacccg tggttgacag caaatatata ctgacgccga aactctggga
    15781 gtatctctat aactacgcca aaaagcacgc agctaagggt aacggattcg gttttggcct
    15841 cgttaatcct gaaaataaaa gcattgcccg tacgctttct gctcgctatc acaaagacgg
    15901 gtctgaaatt ctgatagacc gtggctggga tatggccaca ggtgaaacag acttcgcgaa
    15961 cgaagaaaat caggcgcatc ggccccgtag gctgactcca cgagagtgcg cgcgccttat
    16021 gggttttgaa aaagtagatg gcaggccttt tcgcattcct gtgtcagaca ctcagtcgta
    16081 caggcagttc ggtaactccg tagtggtgcc cgtgtttgaa gccgtagcca aactgcttga
    16141 accttatatc ctgaaagcgg ttaatgccga ttcgtgcaag gttgaacgaa tctggatcgc
    16201 tcctcccggt atttatgccg ggagataatc tatggaatat ctgcgtaaag ctctgtcagc
    16261 tcagcaataa acgcacctag cgtcattagc tcagctctca ccgcctccgg ggtatttttt
    16321 gtgcagagat gatggcacga ccaatctgac acccgactcc cgcatctccc gatattgagc
    16381 cagagaaact ccctcctgga gtgtaaacag atgcacctga tgaattttat cggcctcatt
    16441 cagtatctga cgccagcgat ccttacaggt agtcttgact gccagcatgc gcagattttc
    16501 tacgggaaac tcagtatcgt ggtaagcccc tgcggaaggg aaaaggaaat cgggttttta
    16561 ttaccttctg tgatggcctg cgtcgaaaag tgtcgcaggc cgtgctcaat gaatagatgc
    16621 tcaggtgcag ttccagcgac ttcccggctc tggatttacg gcgattgctg acagaattgg
    16681 ccagcgcaat aaattcatcc acagagccaa atcctttccg gatgatatcc agaacatgca
    16741 gttcctcaac caatagaaat atgtcgtact ccacgcgccg gcggtcaaga agttgctcat
    16801 ccggatcaag ggaatttttc acataatggc tggctgcata ctgaataatt tcacttcccg
    16861 acggaaagcg caggtgccag tcttcaggta gaatatattt atgatttact ggcgcttgct
    16921 gtagagatag tccgcctaga atctgtcctg cggggccggg atagcgcgcc gggtataact
    16981 tcaccaatag cggtctcaat gacgtcctct tcatcagtgc tggcgcatac ccaaatattt
    17041 acttccttac agtccccctt gctcatcaag cttgaaagct aggagcgtca gagcacctgt
    17101 attttcagga ttctgaagtg ggctgcctct accccagcgg gtaatccttt tttcattccg
    17161 ggttttacca aaatgacggc tgttataata aattgcccgg gcttcgctgt cagggcaatc
    17221 atgcgatgac acatgtgcgg tgagaaaaac cgaagggttc agttcacggg tatggttgat
    17281 agacggaaag agtttttcaa cgatacctga agggatataa agtcctacct ggtgaccacc
    17341 tgttgcgccg gtatcgttgg cggaaaggcg tttgatgtag acgaagtaat tctcacatgc
    17401 gatctcgagt agccagttgt ggaaaaccga cataaacatc ccctgttacc ctgaaactct
    17461 actcaccatt ttttcatggc actgttgcaa agttagcgat gaggcagcct tttgtcttat
    17521 tcaaaggcct tacatttcaa aaactctgct taccaggcgc atttcgccca ggggatcacc
    17581 ataataaaat gctgaggcct ggcctttgcg tagtgcacgc atcacctcaa tacctttgat
    17641 ggtggcgtaa gccgtcttca tggatttaaa tcccagcgtg gcgccgatta tccgtttcag
    17701 tttgccatga tcgcattcaa tcacgttgtt ccggtactta atctgtcggt gttcaacgtc
    17761 agacgggcac cggccttcgc gtttgagcag agcaagcgcg cgaccatagg cgggcgcttt
    17821 atccgtgttg atgaatcgcg ggatctgcca cttcttcacg ttgttgagga ttttacccag
    17881 aaaccggtat gcagctttgc tgttacgacg ggagggagat aaaaatcgac agtgcggccc
    17941 cggctgtcga cggcccggta cagatacgcc cagcggccat tgaccttcac gtaggtttca
    18001 tccatgtgcc acgggcaaag atcggaaggg ttacgccagt accagcgcag ccgtttttcc
    18061 atttcaggcg cataacgctg aacccagcgg taaatcgtgg agtgatcgac attcactccg
    18121 cgttcagcca gcatctcctg cagctcacgg taactgatgc cgtatttgca gtaccagcgt
    18181 acggcccaca gaatgatgtc acgctgaaaa tgccggcctt tgaatgggtt catgtgcagc
    18241 tccatcagca aaaggggatg ataagtttat caccaccgac tatttgcaac agtgcccgcc
    18301 attacacagt tggccaacgc gaacagcagt attggtcgca acaaaaaatg aaagaaaaat
    18361 cccccaaatg aagggaaaaa acggaagaac agtcgaacga caggcacaaa aaaacccgac
    18421 tggtaatcgg gctttttcgt gttttccagt cctgagttgg tggctctggc tggagtggaa
    18481 ctgtcttcaa ccaacaccga agaacaaccg atatgacagg cagtgtaaga gtaagtatcg
    18541 ggagtctgct ccatataatg gagtaaacgg atgattgata aagcaatcat cgttctgggg
    18601 gcactaatct cacttcttga attgattcgc taccttctcc agttgatggg ctgatggcgg
    18661 aaacgtaact aaggccgggg gctaaccacc tccggccttt aataaaaaca tattttagtt
    18721 acaatattca aatgcattga ctaaacacca cacacccaat ctcctgagtt aatatcctgc
    18781 cttgcaggta tattagcccc ctactcctct acttactgga tttctgcccg gttttacgtt
    18841 ttagcgcatt actgattgtg ccacggctgc accctagcac tttctgtacc tgtgtccagg
    18901 agctaccgct ttctatcaac ctgataattg catcatgtct ggcttgatta ggtttacgcc
    18961 ctttatattt gccgtctttc tttgctttct ctatcccttg tttctggcgt tcccgacgtt
    19021 gttcatagtc ccttctggca actgcggcca gcatatccag cagcatatcg ttaatggctg
    19081 caaacaaccg gctgtcaaac tcactcatac cagaattaat ccatgtcgtc ggcacattca
    19141 ccgccataac ccggatgtct ttctgccgga tcattttctt caacgtattc cagtcttccc
    19201 ctgacaggcg ggaaagtctg tccacatcct cgataagcaa aatgtcattt tgttggcaat
    19261 ctctcagaag acgaaaaagt tccgggcgct caagacgggt gccggattca ttctcaatat
    19321 agtagctgca aatgatcagg cctctttccc tggcaaaagc ctcgatagtt tccagggcac
    19381 gcgaagcatc ctgttctgct gttgaagctc tcagataagc gcggacaaag cttgttggta
    19441 catttgaagt catattacag aaccggttca cataaggtta caccactata cccaaaatgc
    19501 accagaaagt agatcgacag gaaaggcaca ctcaaaaaga accagaaaac agacctccga
    19561 ccataaagtg acaatgtcac acagaaattt acaacataaa gatgatgtaa agacggtctc
    19621 agatttacca cgtaaagcca ctataaatac acacaaatct ttacacaata aagataacat
    19681 aaatacaagc ttatctttat ttgtgcttta catggtaaat catgtgtaat ataaagacac
    19741 tgtaaagaca aaataatctt tacgaacaac acacaatgta aagataagac agtctttaca
    19801 taatctttac gtcataaaga gaggaattct gaaatgggta aaatcttgct tgtcgtatca
    19861 gataagggtg gtgtaggcaa aagcacctac gtggctaaca caggctcaat gctggtcaat
    19921 aaaggtaagt cggtaattat cctcaagaca gataaaaacc acgatctgtt gagctggaac
    19981 gaaaagcgga cagataacgg cttactcact atcccggttc acgcagctta cggaaacgtc
    20041 agcaatgaaa ttaagcgact tagtaagctg tgtgaagtcc tcattgtcga ttgccccggc
    20101 cacgacagcc aggagttccg tagcgccctg acagtatcag atatcgtggt aacactggtt
    20161 aagccgtcct ctgatttcga aagcgaaact ctgaccagtg ttacagagaa aatccgcacc
    20221 gctcagaaag ctaacgcagc cctggaaccg tgggtgctgt tcaccagaat caactcagcg
    20281 aaaccccgcc acagaaaagc ggccattgat ctggataaat tactgcgttc ggacaacatc
    20341 tggattcaac ctcttaaaac ccggatatcc gagctggatg tgtatgaaag cgcctgtaat
    20401 gaaggggcag gggtacatga cgttagccgg gcatcaagcc tttcaacagc gaaagcacag
    20461 attgaactag tggcgcagga aattggaatt ttatagtaat atcaatacca tctataaatc
    20521 tttacattgt aaagataata taaagatagt atgatattta ctattaatgc ataccgtaca
    20581 aggggaaatt gtcatggctt taaaactaaa ccgtccgaac atcgatgaat ctcagcaacc
    20641 agcaacaaac gcagaaaccg cgcgttttat ctccggcgct accagagcgc ctgtagtggg
    20701 taaaccaaag ttgatgaact tcagactttc agcccatttt gaggacatac tggaagctga
    20761 agctatcaga acagggcaga gcaaaacaac cgttctcaaa gcggcgctgg cgatgtacaa
    20821 cagccaggat gaaaacataa agaatcactg gttgcttgag tctgcaaaat tctaaccata
    20881 gaagcatgga tgaaaatcta tgagatattt aaccgaattg atctgtgacc tctacaggtt
    20941 gacagatcac cataaactga ccacagcaac gtttaaaaat cttgctgata ttaagttatt
    21001 taaacctaca gcagatgcag acaccatatt gcagcttgaa aatatattta gcgaatactc
    21061 actgagatat attgacaagg atctggctga aattctgagc aacttaataa ctacagataa
    21121 gaaacactct ctggacttcg attttaacaa aatacaatct ctgactgact cgaaaagttt
    21181 cggttgtgga tggagcaagg taataaatgg tagttggttc aaagatcttt attcttgggg
    21241 agaggggatg tatcctgccg aaaatctgaa agctgaaaat attttagact ggaaagataa
    21301 tatatggcac attgagcatg aaggtttccc cccacgcccc cctattaatg ttaaatatta
    21361 ttcttggttt gaccgatatg tagcttcaaa cagtggtggc tcacatcatg cagcaatggt
    21421 tgtatatcaa tcagtcagag acgggttaga gtataaaaga gaagctgtta ttaaacaact
    21481 gagtatagac ccaggcactg ttgaaatact tgataagaat tactattcat tcatattcca
    21541 gatcaaaacc cttaataaag aaactagaat ttatacatct gaatacgagt ttacagatgc
    21601 tttaaaagac tttggacaaa acagacatac catacttaaa cctgttaatt acgtttccaa
    21661 cataaaatta gtatttattc caaaagatgc attaaaaaca aatagcgaga cattccgcaa
    21721 ctggtttcat tctgcaatta gctgcggaaa aataatatca ctccctgatt atctgaaaaa
    21781 tccagcacat tatcatacac ttcattactc acatgaagta gactcaataa cacttggcga
    21841 cccaagcaga aaatttaaac tgaaaggaga ttcttagctt ttatataaaa aatcaatgtt
    21901 atcatttgtc agaagatcag cgagggtaat acattcaaga accacaatat ttgttccttc
    21961 caacaaactg gcatcaagta tcttatcgaa gctgataatc atcattggct tgcgttgtgt
    22021 taaatcaaag attaccaatg gaagtattac actgttaatt aattcaaact ctttaaagaa
    22081 agcatcagtg ccatactcac tggctggaaa aagaatctca attaatctca caccataaaa
    22141 aacatggtag ttttctttaa ggttatcctt taaaatatta acagccttag tatatttttc
    22201 gttaataaac tctctcacct gatattccat aaaattctcc gacaagaacc gactgtaggt
    22261 caccgggcaa acgttgcaga atggcgtcag agacgtcatt ttgcggcgtt tgccctatcc
    22321 tgcatcgcag tgaaaaggca gggactggca taactgctga gtagcatcat tgctggctta
    22381 tctcgctact gttctcggtg ctttcgtccg caggttcggg aacaagtaac ttgtgccaag
    22441 gcatagtttt gttgagcagc tccatcagag gctcagccag cagtcccaaa atccaggttg
    22501 ccgtaatcac cggtatagtc agattttgtg gcgtccataa ctggtgatcg agatgatacc
    22561 aagtgatgac acacaaaata ccacccagcc agaatacagc ccatttaaac gcaccaagaa
    22621 tggctaacac aaaaacaaag ataaaatgta aaacactcgc gacaagaaga cgaagataaa
    22681 accatcctca gccaagccac ttaacaaaag tgctccctgt tttcactgca aaacgtttct
    22741 tacgctccct ggcaatttct ttcctgaatt tagcacgttc ttccccctga gggaattgat
    22801 agattttagc catgagctac ctcatttcga tctcaaaacg aagtttatgc aattatcctc
    22861 tgaaaccgta tggtattctg atatctaagc cctcactttc tttatctatt ttataagaaa
    22921 accttagctt tgatgctctt cttgcgactc tctcaacgat tttaacttcg agatgattaa
    22981 tctctgtata ttgatttatt ttttcaatat ttttttgcag aaaaacctta ttaaaatcct
    23041 taaaattctg ataaaggtaa actttttcgc cattatctat tctgaataat tcaagttcat
    23101 cctttaatac atctacttca atgtcgaaaa atgtcttttt accactgctg tattgtttcc
    23161 tgataaactg ataaagcata tttgaatttt gatcagcgag tcttacagac gatatcaaaa
    23221 cctgagtagt gtaagaatcc tttaacatcg tgatatatgg ctcaatgaca tgtgaaaaag
    23281 caatatcaat atatccttca ctttcaacat aatcacaaaa cgcagtcagg ttcataagcc
    23341 tgactgcatc agaaggtaat ttacctctct tcttcgtatg tccagagctt tgattgccct
    23401 gaggtgtgag aagttgattt cgaggaatgc gaataacact ggcctgaagt tcttctgccc
    23461 cctctttcaa ctgccggtaa gcacctgtta catcaatatc agcgataaat gcatattccc
    23521 gagccgtaat acgaaaggtt gccccctcag ataactcttc acgtgaatca atctgcgcca
    23581 tagccataaa caaaattctt ctggcagaca aaggcaacga tgagaatgtg ctgttaattt
    23641 catttctgtg gcgaattttt gttttctttg taacgctcag taagttcata cattacctgt
    23701 ggtttttaag ttctgatggt gaaatcataa ccacaaaggc ggaaatatgt aaagtggttt
    23761 atccacctta tgtatttcca ccaaaacacg gatcacatga aagaattttt atcatttata
    23821 ttcaatatga tagaaatgcg caggtatcca ccttttaacg tcatacgtta aattagagca
    23881 ctataaagaa ctaaagaaat gaagatacaa agatacgaat atctgaataa aaacagaaaa
    23941 atgcgtaccc atccaccttt cagtgcgtac ccatccacct ttcagtgcgc agccatccac
    24001 ctttcatgaa aattacagtg cgtacccatc cacctttcag tgcgtaccca tccacctttc
    24061 attttgaggc gacaaaaaac aacacctatc ttaatgaaat tattgataaa aaagctggca
    24121 caatgtttgc agaataagtt aaagtaagtt aaagatctta aagtagatct accgatctac
    24181 atttaagatc ttaaaaacaa gaagtttaat aagcaaaaaa acacaaaaaa tctgtggata
    24241 actctgctca aaacaaaaaa ttcacagcgc ctgtggataa ctttgcgtaa acccggagga
    24301 cagatcactc tgaaccaaga caaccacaca taaaaacaat atgctcattt tttaaccact
    24361 gtgcgtaagt gcctaatgta atccctgtgc tattccgctt cctcgctcac taactcgcta
    24421 cactcggtcg ttcggctgcg gcgagcggtg tctcctttct caaaaccaga agagttcagc
    24481 tcatacgatc cgttgattga tcctttttgg atctttcact gagaagccct gaatcgcttt
    24541 ctgccgcttc gttcgataca accatggtga aaccatgcga aatcgaaaaa atcgctcaga
    24601 atgcgataca gcgcgtttta gagggtattt acaaaacagt cgttgccttg aggaaatttt
    24661 gatcaagatt gaactcctat ccggatcatg gcaacagatc acagcaacaa ggccgctaaa
    24721 aagcgttgag cggcgttaaa aaccgttaaa ccgtagctga ctacaacgaa acgggaaaaa
    24781 acgctcagaa cgcgttacag agcgttttaa ggcgatgtcg gaaagagcca tatctcacct
    24841 gttctgatgt ttttctcaac ataagcactt ttaagagtgc ttttaaagat gctattatgc
    24901 caatgagaca agcggagggc ttatgagcta tcaaattctg acaactacag cggccagtat
    24961 tactgacctg aaaaaaaatc ctatgggaac cgtagctgaa ggtgaagggg acgctgttgc
    25021 gatcctgaac cgaaacgaac cggcgttcta ttgcgttcca ccaaaacttt acgcctacta
    25081 tcgggaactc gctgaagatg ctgagttaaa cgctgttgct gatgagcgca tgaaaaaccc
    25141 ggaaattgtg aaggttaacc tggatgacct atgaactggc ttttgaccgt agagcactga
    25201 aggaatggca gaaactcggc cacaccatcc gtgaacaatt caaaaagaaa ctggcagaac
    25261 ggctggaaaa tccacgcgta cccgcagccc ggttacatgg tcatgctgat cgctataaaa
    25321 tcaaacttcg tgcatctggc tacagacttg tataccaagt cattgatgag aaagtcgttt
    25381 tactcgttat tgccgttgga agaagggaaa gcagcgaagt ctatcagatc gcagatttgc
    25441 gctaagatta atcatcaaat gattggtgat gctgccaact tactgattta gtgtatgatg
    25501 gtgtttttga ggtgctccag tggcttctgt ttctatcagc tgtccctcct gttcagctac
    25561 tgacggggtg gtgcgtaacg gcaaaagcac cgccggacat cagcgctatc tctgctctca
    25621 ctgccgtaaa acatggcaac tgcagttcac ttacaccgct tctcaacccg gtacgcacca
    25681 gaaaatcatt gatatggcca tgaatggcgt tggatgccgg gcaacagccc gcattatggg
    25741 cgttggcctc aacacgattt tacgtcactt aaaaaactca ggccgcagtc ggtaacctcg
    25801 cgcatacagc cgggcagtga cgtcatcgtc tgcgcggaaa tggacgaaca gtggggctat
    25861 gtcggggcta aatcgcgcca gcgctggctg ttttacgcgt atgacaggct ccggaagacg
    25921 gttgttgcgc acgtattcgg tgaacgcact atggcgacgc tggggcgtct tatgagcctg
    25981 ctgtcaccct ttgacgtggt gatatggatg acggatggct ggccgctgta tgaatcccgc
    26041 ctgaagggaa agctgcacgt aatcagcaag cgatatacgc agcgaattga gcggcataac
    26101 ctgaatctga ggcagcacct ggcacggctg ggacggaagt cgctgtcgtt ctcaaaatcg
    26161 gtggagctgc atgacaaagt catcgggcat tatctgaaca taaaacacta tcaataagtt
    26221 ggagtcatta ccctg
//
