LOCUS       NZ_AP026776            25968 bp    DNA     circular CON 27-NOV-2023
DEFINITION  Enterococcus faecium strain NUITM-VRE1 plasmid pNUITMVRE1_3,
            complete sequence.
ACCESSION   NZ_AP026776
VERSION     NZ_AP026776.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMD00533729
            Assembly: GCF_025998395.1
KEYWORDS    RefSeq.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1
  AUTHORS   Suzuki,M., Hashimoto,Y. and Tomita,H.
  TITLE     Complete genome sequence of Enterococcus faecium NUITM-VRE1
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 25968)
  AUTHORS   Suzuki,M., Hashimoto,Y. and Tomita,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-SEP-2022) Contact:Masato Suzuki National Institute of
            Infectious Diseases, Antimicrobial Resistance Research Center; 4-2-1
            Aobacho, Higashimurayama, Tokyo 189-0002, Japan
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Canu v. 2.1.1
            Genome Coverage                   :: 200x
            Sequencing Technology             :: Illumina HiSeq; ONT MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/27/2023 03:20:54
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,228
            CDSs (total)                      :: 3,138
            Genes (coding)                    :: 2,975
            CDSs (with protein)               :: 2,975
            Genes (RNA)                       :: 90
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 163
            CDSs (without protein)            :: 163
            Pseudo Genes (ambiguous residues) :: 0 of 163
            Pseudo Genes (frameshifted)       :: 65 of 163
            Pseudo Genes (incomplete)         :: 91 of 163
            Pseudo Genes (internal stop)      :: 36 of 163
            Pseudo Genes (multiple problems)  :: 25 of 163
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AP026776.1.
            Annotated by DFAST https://dfast.ddbj.nig.ac.jp/
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..25968
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /strain="NUITM-VRE1"
                     /db_xref="taxon:1352"
                     /plasmid="pNUITMVRE1_3"
                     /geo_loc_name="Viet Nam:Hanoi"
                     /lat_lon="20.99138062 N 105.86277218 E"
                     /collection_date="2021"
     gene            complement(9..>389)
                     /locus_tag="OO969_RS15820"
                     /old_locus_tag="NUITMVRE1_31260"
                     /pseudo=""
     CDS             complement(9..>389)
                     /locus_tag="OO969_RS15820"
                     /old_locus_tag="NUITMVRE1_31260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="toxin zeta"
                     /name="toxin zeta"
     gene            325..900
                     /locus_tag="OO969_RS15825"
                     /old_locus_tag="NUITMVRE1_31270"
     CDS             325..900
                     /locus_tag="OO969_RS15825"
                     /old_locus_tag="NUITMVRE1_31270"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="WP_230307287.1"
                     /translation="MTTISCACFGGALAVIGSSAYNKIHERPSAANERLEIGNWEADTV
                     AGKTGRARIVTLVDRRSRFSLLGKVEKKISKNVVDCMINLLRNVGEDKCKTVTPDRGKE
                     FSQHSRITLELNGTKVYFPDPHAPWQRGTNENTNGLLREYSPKGEDISGIFDSQIQEWA
                     NKLNTRPRKCLNWKTPYEVFFNESLHLI"
                     /name="IS30 family transposase"
     gene            complement(972..2585)
                     /gene="narB"
                     /locus_tag="OO969_RS15830"
                     /old_locus_tag="NUITMVRE1_31280"
     ARG             complement(976..2585)
                     /name="narB"
                     /gene="narB"
                     /gene_name="ionophore ABC transporter permease subunit
                     NarB"
                     /tool="amrfinderplus"
                     /drug_class="IONOPHORE"
                     /identity="99.44"
                     /coverage="100.0"
     gene            complement(2609..>2941)
                     /gene="narA"
                     /locus_tag="OO969_RS15835"
                     /old_locus_tag="NUITMVRE1_31290"
                     /pseudo=""
     CDS             complement(2609..>2941)
                     /gene="narA"
                     /locus_tag="OO969_RS15835"
                     /old_locus_tag="NUITMVRE1_31290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326774.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="ionophore ABC transporter ATP-binding subunit
                     NarA"
                     /name="narA"
     gene            complement(2996..3676)
                     /locus_tag="OO969_RS15840"
                     /old_locus_tag="NUITMVRE1_31300"
     CDS             complement(2996..3676)
                     /locus_tag="OO969_RS15840"
                     /old_locus_tag="NUITMVRE1_31300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            complement(4109..4321)
                     /locus_tag="OO969_RS15845"
                     /old_locus_tag="NUITMVRE1_31310"
     CDS             complement(4109..4321)
                     /locus_tag="OO969_RS15845"
                     /old_locus_tag="NUITMVRE1_31310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002324171.1"
                     /translation="MIPLYRIVLIVGMELKTLKKEQLFKVKERHNQLLCSKTGTMNIEY
                     RTEYLELTNQTDFLLIRKQQEQEKN"
                     /name="hypothetical protein"
     gene            complement(4342..5193)
                     /locus_tag="OO969_RS15850"
                     /old_locus_tag="NUITMVRE1_31320"
     CDS             complement(4342..5193)
                     /locus_tag="OO969_RS15850"
                     /old_locus_tag="NUITMVRE1_31320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_002287227.1"
                     /translation="MKSDDWIEHTWLPLKRNSKRKKFWVLQLWPLGKLCSYGARLILDL
                     TVYSIGVFGTAYYLINDPNRIAASDIFTVLMTLIFVMLLSIFTQLVMQFTRQKLTAGKL
                     FKSLFDLIVVNAILATLIKQIEQSGRTTKGVKDFLLTFIHFVNGHMYLFEVGIILFFVG
                     YVSTKLIKRSIEKEIEIDLIPTLLGYEYNVDFGRYDELINTDIVHTSIHESTVKGIRSI
                     LKNGQEMKAIDRRKEIYNFYEVEASLRYGIGKLWLDGSNIRQNKPYIFWNSSDLELPMK
                     DK"
                     /name="hypothetical protein"
     gene            complement(5294..5590)
                     /locus_tag="OO969_RS15855"
                     /old_locus_tag="NUITMVRE1_31330"
     CDS             complement(5294..5590)
                     /locus_tag="OO969_RS15855"
                     /old_locus_tag="NUITMVRE1_31330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication control protein PrgN"
                     /protein_id="WP_000053907.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTRE
                     KTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELRKRKKYIQ"
                     /name="replication control protein PrgN"
     gene            complement(5725..7218)
                     /locus_tag="OO969_RS15860"
                     /old_locus_tag="NUITMVRE1_31340"
     CDS             complement(5725..7218)
                     /locus_tag="OO969_RS15860"
                     /old_locus_tag="NUITMVRE1_31340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="WP_000947691.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSKQ
                     LMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINTFV
                     VDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVIDVA
                     KKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSMKLES
                     DQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTLSLAYY
                     SSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELCQQWVSP
                     TLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLNLSKKELA
                     SQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLSKEKRLDYS
                     TRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
                     /name="primase C-terminal domain-containing protein"
     gene            7830..8783
                     /locus_tag="OO969_RS15865"
                     /old_locus_tag="NUITMVRE1_31350"
     CDS             7830..8783
                     /locus_tag="OO969_RS15865"
                     /old_locus_tag="NUITMVRE1_31350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="WP_000429439.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLFE
                     KDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGSPG
                     SEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAADYII
                     AMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQKTID
                     KYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYYEQHGD
                     IEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
                     /name="ParA family protein"
     gene            8755..9030
                     /gene="prgO"
                     /locus_tag="OO969_RS15870"
                     /old_locus_tag="NUITMVRE1_31360"
     CDS             8755..9030
                     /gene="prgO"
                     /locus_tag="OO969_RS15870"
                     /old_locus_tag="NUITMVRE1_31360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA segregation protein PrgO"
                     /protein_id="WP_001196543.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVDP
                     PVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
                     /name="prgO"
     gene            9258..9938
                     /locus_tag="OO969_RS15875"
                     /old_locus_tag="NUITMVRE1_31370"
     CDS             9258..9938
                     /locus_tag="OO969_RS15875"
                     /old_locus_tag="NUITMVRE1_31370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            10182..10787
                     /locus_tag="OO969_RS15880"
                     /old_locus_tag="NUITMVRE1_31380"
     CDS             10182..10787
                     /locus_tag="OO969_RS15880"
                     /old_locus_tag="NUITMVRE1_31380"
                     /EC_number="2.7.7.108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein adenylyltransferase Fic"
                     /protein_id="WP_000599739.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTFK
                     GLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEIIKK
                     YVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDLEIR
                     YLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
                     /name="protein adenylyltransferase Fic"
     gene            10803..11375
                     /locus_tag="OO969_RS15885"
                     /old_locus_tag="NUITMVRE1_31390"
     CDS             10803..11375
                     /locus_tag="OO969_RS15885"
                     /old_locus_tag="NUITMVRE1_31390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000170424.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRDR
                     PKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTSMG
                     RMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELLTSG
                     KSYKEVEAITGFSRSTLFRIKKKIEES"
                     /name="recombinase family protein"
     gene            complement(11808..12767)
                     /locus_tag="OO969_RS15890"
                     /old_locus_tag="NUITMVRE1_31400"
     CDS             complement(11808..12767)
                     /locus_tag="OO969_RS15890"
                     /old_locus_tag="NUITMVRE1_31400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558064.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element IS1252 family transposase"
                     /protein_id="WP_000222577.1"
                     /translation="MTYTHLTTDELVMIESYYHQNIKIVKIAEYLKRSRTPIYNVINFL
                     KEGHTALEYYQQYKENKKRCGRRNIVLPKKQQSYIKEKIAQGWTPDVIIGRKEKPISCS
                     VRTLYRQFKEKVFDESTLPMKGKRKPNGHQERRGKQAFKRNIVERETDYPTFKEEFGHI
                     EGDTIVGIHHKSAVITLVERLSKIIITLKPEGRKAIDIENTLNHWFGSIPRHLFKSITF
                     DCGKEFSNWKALSNQHDIAIYFADPGTPSQRALNENSNGLLRKDGLPKNMDFNQVDQAF
                     ISSVANKRNNIPRKSLDYQTPLEVFMSYMNEDILSSLI"
                     /name="IS30-like element IS1252 family transposase"
     gene            complement(12895..13575)
                     /locus_tag="OO969_RS15895"
                     /old_locus_tag="NUITMVRE1_31410"
     CDS             complement(12895..13575)
                     /locus_tag="OO969_RS15895"
                     /old_locus_tag="NUITMVRE1_31410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            <13650..14363
                     /locus_tag="OO969_RS15900"
                     /old_locus_tag="NUITMVRE1_31420"
                     /pseudo=""
     CDS             <13650..14363
                     /locus_tag="OO969_RS15900"
                     /old_locus_tag="NUITMVRE1_31420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /name="C40 family peptidase"
     gene            14360..15292
                     /locus_tag="OO969_RS15905"
                     /old_locus_tag="NUITMVRE1_31430"
     CDS             14360..15292
                     /locus_tag="OO969_RS15905"
                     /old_locus_tag="NUITMVRE1_31430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="WP_001224319.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYKVNPHKKVVIALWVLL
                     GLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKSIDN
                     RMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQLITE
                     GENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSITTNEI
                     NEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVTVSLTVE
                     YIDQQTKATQVSQFDLVLEKNGSNWKIVK"
                     /name="conjugal transfer protein"
     gene            15537..15653
                     /locus_tag="OO969_RS15910"
     CDS             15537..15653
                     /locus_tag="OO969_RS15910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="WP_001791010.1"
                     /translation="MILKYPENICMLCIPMVMHKNPSDKSIYHWDFYALLGF"
                     /name="tetracycline resistance determinant leader peptide"
     gene            15669..17588
                     /gene="tet(M)"
                     /locus_tag="OO969_RS15915"
                     /old_locus_tag="NUITMVRE1_31440"
     ARG             15670..17585
                     /name="tet(M)"
                     /gene="tet(M)"
                     /gene_name="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /tool="amrfinderplus"
                     /drug_class="TETRACYCLINE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            17782..19158
                     /gene="tet(L)"
                     /locus_tag="OO969_RS15920"
                     /old_locus_tag="NUITMVRE1_31450"
     ARG             17783..19155
                     /name="tet(L)"
                     /gene="tet(L)"
                     /gene_name="tetracycline efflux MFS transporter Tet(L)"
                     /tool="amrfinderplus"
                     /drug_class="TETRACYCLINE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            <19753..20064
                     /locus_tag="OO969_RS15925"
                     /old_locus_tag="NUITMVRE1_31460"
                     /pseudo=""
     CDS             <19753..20064
                     /locus_tag="OO969_RS15925"
                     /old_locus_tag="NUITMVRE1_31460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000277654.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /name="replication initiation protein"
     gene            20199..20846
                     /locus_tag="OO969_RS15930"
                     /old_locus_tag="NUITMVRE1_31470"
     CDS             20199..20846
                     /locus_tag="OO969_RS15930"
                     /old_locus_tag="NUITMVRE1_31470"
                     /EC_number="2.3.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000143686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type A-8 chloramphenicol O-acetyltransferase"
                     /protein_id="WP_002403315.1"
                     /translation="MTFNIINLETWDRKEYFNHYFNQQTTYSVTKEFDITLLKSMIKNK
                     GYELYPALIYTIVNIINQNKVFRTGINSEGNLGYWEKLNPLYTVFNKETEKFSNIWTES
                     NVSFNSFYNSYKSDLLEYKDKNEMFPKKPIPENTVPISMIPWIDFSSFNLNIGNNSRFL
                     LPIITIGKFYSKNNKIYLPVSLQVHHAVCDGYHVSLFMSEFQNIVDSVNEWI"
                     /name="type A-8 chloramphenicol O-acetyltransferase"
     gene            21099..22310
                     /gene="mobV"
                     /locus_tag="OO969_RS15935"
                     /old_locus_tag="NUITMVRE1_31480"
     CDS             21099..22310
                     /gene="mobV"
                     /locus_tag="OO969_RS15935"
                     /old_locus_tag="NUITMVRE1_31480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004906452.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /protein_id="WP_002328823.1"
                     /translation="MSFAVARMQKVKSGNLVGVGNHNQRNTDNHSNKDIDVERSHLNYD
                     LVNRTENYKRDIEQFINDNKSSSRAVRKDAVLINEWIITSDNPFFKDKDDKEIKDFFDT
                     AKSYFADKFGDNNIRYAQVHLDETTPHMHLGIVPFNDEHKLSAKTVFNRQALQAVQDEL
                     PKYLNERGFELERGEKGSERKNLTVPEYKKAKDELKEITTTLEQRKSEVLALSNDKAPT
                     IKKESLDLKDETKTVKVPSGETIGIGKLRHEFMKNEERKTGNVIIPESKLNAVIKSYEE
                     LYKANEKLKNYAETDLPKEITRVKEKYRELAKDYNRLVRKSNQNIETLEELEKENKSLK
                     NEIKGIYKGFNQFMENTLGATVGQAKKLMNNLMSEVKEFVKGGEFEKIHRNETKTRDRD
                     ELSR"
                     /name="mobV"
     gene            22854..23009
                     /locus_tag="OO969_RS15940"
                     /old_locus_tag="NUITMVRE1_31490"
     CDS             22854..23009
                     /locus_tag="OO969_RS15940"
                     /old_locus_tag="NUITMVRE1_31490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein RepA"
                     /protein_id="WP_002328822.1"
                     /translation="MVEVEKKKVTLSLPVESNDKLEKMAQKYGMTKSGLVTFLINQADD
                     KGTIFK"
                     /name="protein RepA"
     gene            23133..23660
                     /locus_tag="OO969_RS15945"
                     /old_locus_tag="NUITMVRE1_31500"
     CDS             23133..23660
                     /locus_tag="OO969_RS15945"
                     /old_locus_tag="NUITMVRE1_31500"
                     /inference="COORDINATES: protein motif:HMM:NF013849.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="WP_264879952.1"
                     /translation="MENENRTDWTLPRKNLNPKTKQPYKRGRNWWIVVYPESLPENWKE
                     IISTEPVAISPLHDKDVNADGTKKKPHYHIVFNYKGNKSFEQMDEMARVLRAPIPERIS
                     GLTGAVRYLTHMDNPEKYQYDNTEIQVFGGFDLESCLALSTGDKRQALKEMLGFISDNN
                     IMHLKVLLQSFK"
                     /name="replication protein"
     gene            complement(23690..24370)
                     /locus_tag="OO969_RS15950"
                     /old_locus_tag="NUITMVRE1_31510"
     CDS             complement(23690..24370)
                     /locus_tag="OO969_RS15950"
                     /old_locus_tag="NUITMVRE1_31510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="WP_001015311.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            <24665..24744
                     /locus_tag="OO969_RS16210"
                     /pseudo=""
     CDS             <24665..24744
                     /locus_tag="OO969_RS16210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502600.1"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /name="peptide-binding protein"
     gene            24793..24876
                     /locus_tag="OO969_RS15955"
     CDS             24793..24876
                     /locus_tag="OO969_RS15955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuator leader
                     peptide ErmL"
                     /protein_id="WP_031929417.1"
                     /translation="MLVFQMRYVDKTSTVLKQTKNSDYADK"
                     /name="23S rRNA methyltransferase attenuator leader peptide
                     ErmL"
     gene            25001..25738
                     /gene="erm(B)"
                     /locus_tag="OO969_RS15960"
                     /old_locus_tag="NUITMVRE1_31520"
     ARG             25002..25735
                     /name="erm(B)"
                     /gene="erm(B)"
                     /gene_name="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /tool="amrfinderplus"
                     /drug_class="LINCOSAMIDE/MACROLIDE/STREPTOGRAMIN"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             20200..20843
                     /name="catA"
                     /gene="catA"
                     /gene_name="type A-8 chloramphenicol O-acetyltransferase"
                     /tool="amrfinderplus"
                     /drug_class="PHENICOL"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             20200..20846
                     /name="catA8"
                     /gene="catA8"
                     /gene_name="chloramphenicol acetyltransferase (CAT)"
                     /tool="rgi"
                     /drug_class="phenicol antibiotic"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             25002..25738
                     /name="ErmB"
                     /gene="ErmB"
                     /gene_name="Erm 23S ribosomal RNA methyltransferase"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; lincosamide antibiotic;
                     streptogramin antibiotic; streptogramin A antibiotic;
                     streptogramin B antibiotic"
                     /identity="98.78"
                     /coverage="98.79"
     Typing          complement(5726..7218)
                     /name="rep_cluster_185"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.866"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          19781..20064
                     /name="rep_cluster_1118"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="3.17e-147"
     Typing          21100..22307
                     /name="MOBV"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="87.841"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 tttaaggttt aaatacctgg aagtttaggt gttttgggta ttggtggtgt aggtggctgc
       61 aagctttcca atttttgttg aattgcttta aattcagggg tttcttggtg ttgattttga
      121 accatttttt gctctattct ctccaaagtc ggttgaattt ctttccctga tactttacga
      181 tttaattctc tttctaaggt ctctttcgga ctaatggaag gcgtttctaa gcttgaatag
      241 agtttcactc cttctctatt gtaaagcctt atatcgctaa ataagcccgt tttatgaagg
      301 gtttctaaat tggtcggtaa gtttttgaca acaatatcat gcgcttgttt tggtggtgcc
      361 ctagctgtca ttggatcatc tgcatacaat aagatccatg aaaggccatc tgctgccaat
      421 gagcgccttg agattggtaa ttgggaagct gatactgtag ccggtaaaac aggtagggct
      481 cgtattgtaa ctctagtcga tcgtagatct cgtttctccc tacttggtaa ggttgaaaag
      541 aaaatctcta aaaatgtggt tgattgtatg atcaatctac taagaaatgt aggagaagat
      601 aaatgtaaaa ccgttacacc cgatagagga aaagaattct cccaacatag tcgaataacg
      661 ctagaattaa atggcactaa agtgtatttt ccagatccac atgctccatg gcaacgtggt
      721 acaaacgaaa atactaatgg tttattacga gaatattcac ccaaaggtga agatatttca
      781 ggtattttcg atagtcaaat tcaagaatgg gcgaataaat taaacacgcg accacggaaa
      841 tgtctaaatt ggaaaacccc ttatgaagta ttttttaatg aatcgttgca cttaatttga
      901 caattgaagc cataaaaaaa ccgctcaaat cgactttcgt aaatatgaac ggttttttag
      961 aaattcaatt tttaagcgcc ttctaccata tcacggcgtt tgtatcctaa atagccgaca
     1021 aataagaaga cgatactgat aacagtaatt actgcaaaaa tcgttccatc aaatttttcc
     1081 atcggtaagc gtggaatcca actttgaatt gcagtttttg agaaccaatc cggcaaatct
     1141 aagattccgc cgaaataatt caaagcaaag gaatagccta gataagcata gattactttt
     1201 ccaaattttg gcaaccagcc taacgctaaa gcagccaaac caatataaaa taagatggaa
     1261 gggagaaaat tgtatccagc agctaagaaa tcggtcagat ccatagtcga ttcatttttc
     1321 atcgcagaaa tcgccgttcc acctaatccc gctgatgcta agccaatacc tacgactcca
     1381 gcaaaaatag ctaaaaatat cgttgtccaa tataattggc ctcgcgtaat cttcgttaca
     1441 tacagttgac tcagatgcag tcttgtttct tctgcaaata atttattgac caccgcgatt
     1501 ggcaagattg tgactaatcc aatcattacc atcatgatcg ttgccgtaaa ggattcttca
     1561 atggaaacgc cagattgagt gaacatttgt ttcatcagtt catttccgcc aagaaagact
     1621 tgcatgtctc cataaatgga gccatacgca gctcccataa cgacaaatgc gatcagccaa
     1681 ccaatcatta ctcctttatt aatcttgaaa aacaaaccag gtacagaaag tagtgatttc
     1741 ttcgccgtcg cacgtccttc tcgttcagga agataacctg cgcccatgtc gcgatgttct
     1801 tccaacacaa acgcaagtac ggtaaaaaca agactaaaaa tcaaagcaaa taataatggt
     1861 agccagttat tttctgtgaa aggataggtc aagtaaatcc atcccattgg attgaacatt
     1921 gataaatcaa gattagacac atctgttcca gcgcgcacga tatacaaaag tcctataaga
     1981 cttaatgtcg agccggttgc tccagtagaa gtcgccataa tctgcgacat cacaagtgcc
     2041 aatacaccac cgataattcc cgccaatgca attgatcctc cgaacaagaa agctccttcg
     2101 gcatcaatcg tttttacacc aaaactcatc atgagtccgc cgattaaaag acctaataaa
     2161 agattgatca acagcatctc actgataaca gctaatgaat tggcttgtcg tcctactcga
     2221 aatgagcgaa ccaattcagt caaacctaat tcttcttctt ttcgcgtgtg gctcaccaca
     2281 tgaagtgctg agataatcat tgcgaacaat ccgcaaaaca gcaacatctc ttgagcatac
     2341 atcgctccta aagtataatc cgtacctatt ttgattggtg taggtccaac catcgagatc
     2401 atcgctggat tttgcatcgt ttcaaacatc cctaaaagac cttgtccttt agcaatctct
     2461 tcaaatgctg gtacaaatgc tcctgagaac aaacccaaac ctaaaaccca aacaattatt
     2521 tttttccaat cgcgtttcac gtattgaatg aacaatacgt tccaacgggc aaatttttca
     2581 ttcattttct tttcctccgt tccgacaatc agccttcgta atgacgcatg aatagatctt
     2641 caagcgttgg cggtacagat tcgatttttg tcacacctaa tttggttgcc tcggtcagaa
     2701 tcgtattcat cgcttcattg tcagcagaaa aagttgcttt gccgtctttt tgaacaaaat
     2761 catgcacgcc agagagcgtc gcaagtttct caatatcgcc ttctgtcacc aatgtaactg
     2821 ttgagcgagt caaatgacgc aattcatcta atgtacctgt ttcaactact tctccacgtc
     2881 gaatgattgc tactttatct gctaatcgtt caacttcact taaaatatgt gaagataata
     2941 gggttctgtt gcaaagtttt aaataaagaa taaaatccct tacggtatct atgatttaag
     3001 ctgggattcc caataatacc ttgatttcag tacagaccga aaacccgaag agagtgcctt
     3061 cttttcgggt tttcttatat aatcctcgaa tggcttccat gcctttaatc gtggtagagg
     3121 cagtgcgtaa acttcgatag aatttattgc gtctctttac tggacgatgg tcttgttcaa
     3181 tcaaattatt caggtattta atggtacgat gttctgtccc ttgataaaag ccgtattctt
     3241 ttagtttctt aaaggcactt gtaatagagg gggctttatc tgtgactaca accttcggtt
     3301 catcaaactg cttcactaac cgcttaagaa aagcataggc tgcttgtgtg tcccgttttt
     3361 tacgtaacca aatatccaag gttaaaccat ctgcatcgat ggctcgatac aaataatgcc
     3421 attttccttt aattttgatg tacgtttcat ccattttcca tgaataaaag gattttttat
     3481 ttttcttttt ccaaatttga tagagtagtt tgccatattc ttgcacccaa cgataaatcg
     3541 tcgtatgaga aacgttaatg ccacgatcat ataagatttc ttgaacttca cgatagctaa
     3601 ggttataacg aagatagtag cccacggcta caataatcac atcctgctga aattgctttc
     3661 ctttaaaatg attcatcgtc attcctcctg ctatcttttt ctattattct accttatttg
     3721 atagtagatt taaaactttg caacagaacc gttcgtcaca tcttcgatca atttctctta
     3781 cgattttctc atccacattt cttattctta cttccatatt aattcctcca atttaaaaag
     3841 gatagcgaaa aggagcctat cctttttgct atcctactac cctcctttta ctatccttca
     3901 ctatcctttc actatcctat ttttaaatat tttgttccca catttatttt tgagaaacgt
     3961 aataggcaca gcctattgga acactttttt taaaaagtgt tcccacgttt ccttatgctc
     4021 tttacaaata aaggctttta gagacgttct ggaattttag attccttgaa ttgttcccat
     4081 tcatcaatca attggctata agtagccatt aatttttttc ttgctcttgt tgctttcgaa
     4141 tcaacaaaaa atcagtttga ttcgttaatt ctaaatattc tgttcggtat tcaatgttca
     4201 tcgtacccgt tttactacat agtaactgat tatgacgttc tttcactttg aataactgct
     4261 ccttctttaa ggtttttaac tccatgccaa ctataagcac aatcctgtat agaggaatca
     4321 ttttcaaacg attctccata attatttatc tttcattgga agttctaaat cactactgtt
     4381 ccaaaaaatg tatggtttgt tttgacgaat attacttcca tctaaccaca attttccgat
     4441 gccatatcgt aggcttgctt cgacttcata aaaattgtag atctcttttc ttcgatctat
     4501 tgctttcatt tcctggccat tttttaaaat agatctgatg cccttaacag tagattcatg
     4561 gatactcgtg tgaacgatat ccgtattgat caattcgtca tatcttccaa aatcaacatt
     4621 gtactcataa ccaagaagtg tcggaatcag gtcaatttca atttcttttt caattgaacg
     4681 tttaataagt ttcgtggata catacccgac aaaaaagaga ataataccca cttcaaacaa
     4741 atacatgtgt ccatttacaa agtgaataaa cgtcaataaa aaatccttca ctccttttgt
     4801 tgttcttcca gattgttcaa tttgttttat taaagtcgct agaattgcat ttacaacaat
     4861 taaatcgaat aggcttttga aaagttttcc tgctgttaat ttttgcctgg taaattgcat
     4921 gactaattga gtaaaaatag acaatagcat gacaaaaatc aacgtcatta gcactgtaaa
     4981 aatgtctgat gctgcaatcc tattgggatc atttatcaag taataagccg ttccaaatac
     5041 tccaatcgag taaacggtta aatcaagaat aagtcgtgcc ccgtaactac aaagttttcc
     5101 taatggccat aattgcaata cccaaaattt ctttcgtttg ctatttcttt tcagaggaag
     5161 ccaggtgtgt tcaatccagt cgtccgattt catttcgatt tcttccctaa attctttcct
     5221 ttaacgtttt cctttgctac tttagcagcg ataggttgct caatgaacca attttttaag
     5281 taaataaaaa ctactactgg atatacttct tcctttttct taactcgtta gctattttat
     5341 actcaatata ctcctgctct aacacacaca aacaatcata tacctgatcc atagtctccc
     5401 cagaagctaa ggacaaccca tgaagaaact caatcggcaa agaagcaact gttttttccc
     5461 tggtaaccca agaagacaaa gtcccctgct taaaaccata aagctcacag aacacttcca
     5521 cagataatcc caaacgacca atgataaaca cattaacagg atgtgaatag acataatttt
     5581 ttaacgacat acaacttcct ccatgataca taagactgca tacgcagtta taagtatacc
     5641 acctacacgt agctaggcaa agggagcaac acctacagaa gtatcataga tatattgtat
     5701 agggcaattt gcacctttta tttttcaacc tgtatctact tcaaaaagat tcacttcttt
     5761 aagagggttc aagggggttg ataattgtct aaatgtctct tctactaagc tctcgttgag
     5821 tccaaatacc tctgtgatcc ttgttgaata atctagtctc ttttctttac ttagttgaat
     5881 aaccctcgcg aacaacgttt tgactgaagc aatgatcatt ccgccatttc ttcctcgtgt
     5941 taccttgtag aagactttat tctcctctcg taactcattt aagatcttat caagtgttcg
     6001 cttgggcatc gttagttgtg aagccaattc tttttttgac aggttcaaat aaggctcact
     6061 agcaagactt ttttcgctta gataagccaa tagatcttct ttccattcat ttttatgact
     6121 atattttctt tgatctcgtg gctttttaaa tttccaccag ccacgtcgtt gaatgaacag
     6181 atcattattt tttaaggttg gtgaaaccca ttgctggcac aattcaataa tgaattctct
     6241 gcttgctgct tgataattac cagaataagc actacgtaca atctttacta attctgcttc
     6301 agatagcggt tcctgtaacc gttcgttgaa tgtgaacata ttgtattcgc aagtatccaa
     6361 tgcataacct gaagagtaat aagctaaaga aagcgtgaaa atcacattat ttcgaccaag
     6421 acgtccttct ccgccgacga tgtttgcttt atgaagtaac atatcgaacc acggttcatc
     6481 tacttgacga atttcttttt tctcaggaaa gacaattagt tttcgttctc gatcttcttt
     6541 tgttttttga tctgattcaa gcttcatcga ccattgaatc cagtcagcaa aagaatactg
     6601 atagttcatt tctttaaaaa caatattatt ttcttgtggg aatcgagcaa ttccgaagtg
     6661 gttacatcct agatccactc cggacaattt ttcagccaac tgtagacgaa ttgtttttga
     6721 aatttttttt gctacatcga tcaccttgaa attgcttttc tttgtgacat agcctggtgt
     6781 ctttagtaca aaataaactt gataaccatg atctgattct aaaattagcg ttggcatgta
     6841 gcccacttga tctaaacagg ctaaaataat ttcgccttga tggttctctt ttgaatcgat
     6901 atcaactaca aatgtgttga tttgacttaa gtttttctca gaatgacctt taaccactgt
     6961 tcgataatca tccgcataag taccaaagcg ataggtatta ggtgtccaat gcgttagttt
     7021 cttttcgttc tctaaaatag cttcttccga agtaatgacc ataccacgcc caacattcat
     7081 taattgcttg ctacggtacg caaagatagc accactccta ctggaatcaa tatgacctgc
     7141 aggtttcatg gtgctgtttc gatatttgta tgtacgtaag ccgtttttaa gaatagctga
     7201 ataaatttcg ctcaacatcg attgtaacgt cctttctcaa acaaaaagag aacacagttt
     7261 agctttaatc tcagccatag tatgtgttct ctcttcagtg tttaagaata tttaatttaa
     7321 gtacactaaa taaactttct tctgttgagt tgctcgcctt tttttggtag aataaaggca
     7381 atcggaaaag gtatccgatc aacttttaat ataagtagtt ggtagctact tacatattct
     7441 tgagacgagc gtgaacacat gtcctaacca tgtgattcag aaataattga ttctgctaaa
     7501 atcaattatt tccgtctctt ttttttatgt aatttttctg tttaaagagt accactgctt
     7561 ttgctacttt gtaaatagtg aattatctgt ggtttctata gaattaagtt tacctctttt
     7621 cactctaaat tgtcaacgca aaacgcacaa atatattttg acattttgaa tatatctgat
     7681 atactgaata tagcaaatat atttagtata tccactatat tccttataaa gtctgaattc
     7741 ttatcaattt ggagtatatt agatatatcg aatatattaa gtatatgaag tatactaaat
     7801 atatttagta taggaaattg gagggaacta tggaaaactt acggactgca tttaaaacat
     7861 cagataaact aggaaaagtt gtaatgctta caggtagaaa aggcggcatt ggtaagacta
     7921 cagacaatga tttattagcg attgtttcta gtcaactttt tgaaaaagac gtgttgctaa
     7981 ttgattatga ccaacaaaga aatactactt ccaacattgg atcaacgtat caaattacta
     8041 gctttgatcg atccatgtct gcagcaatca aaaaagggga ctgggtttca ggtattactc
     8101 aagtaagtcc acatttatat attatggctg gctctcctgg atctgaagaa cttaatgaat
     8161 acttgtccga aaaatatcct gatcgtcgta agagatcatt ggccttcatt aaacctttag
     8221 aagaattgag aaaaaatttc gattatatct ttatcgactg cccaccatca acagataatg
     8281 tggttcgtgc attcttaact gctgcagatt atattattgc aatgcaagaa ttaaaacggt
     8341 acgcaatgga aggaacagaa gattttatta ataaagtttt agttccgatt gtcacgaatt
     8401 ttgaagagtc tcatcttcaa atcattggaa ttttgcctgt tcttttctca gtgcgacgtt
     8461 cctctcaaca cgcaaactat caaaaaacaa ttgataagta tggtgaatca aacattttta
     8521 aaagcattgt taaaggctcg gatcggttag aaatgtatgg tgagaatggt atccaattaa
     8581 atgattatgt agatcgaaga tggtgggcta tttttgcaga catctttaca gaattagaag
     8641 aaagaattga atactatgaa caacatggtg atattgaagg atttgattat acacctaaat
     8701 atgctgactc aatggccaat catatcctac ctcttggaaa ggagattaaa ctaaatggca
     8761 ttattaccaa cgaacaaaga taagaagaaa attggtgctg aagatatttc aattaaagat
     8821 gatattaatg tcgagttagg ggaacgaaag tacactgcga aagaaagaaa accagttcaa
     8881 gtagatcctc ccgtactaaa aaccattcgg gatcttagtt atgcaaaaga tattcctatg
     8941 tatgaaatag tcaaacttgc aatggacgcc tatgttgata ctttaaacga cgaggaacgg
     9001 attatatata atagacgatc aaaagattaa aatatagtaa gtatactaga tatagtaaat
     9061 atatttagta tacttactat atttttagct ttattaatcc taatccttca aaatatgtgt
     9121 attgtttggg ggtatacaac attcacaaat tttattgttt ctagttttta ctatactaaa
     9181 tatggttctg ttgcaaagtt ttaaatctac tatcaaataa ggtagaataa tagaaaaaga
     9241 tagcaggagg aatgacgatg aatcatttta aaggaaagca atttcagcag gatgtgatta
     9301 ttgtagccgt gggctactat cttcgttata accttagcta tcgtgaagtt caagaaatct
     9361 tatatgatcg tggcattaac gtttctcata cgacgattta tcgttgggtg caagaatatg
     9421 gcaaactact ctatcaaatt tggaaaaaga aaaataaaaa atccttttat tcatggaaaa
     9481 tggatgaaac gtacatcaaa attaaaggaa aatggcatta tttgtatcga gccatcgatg
     9541 cagatggttt aaccttggat atttggttac gtaaaaaacg ggacacacaa gcagcctatg
     9601 cttttcttaa gcggttagtg aagcagtttg atgaaccgaa ggttgtagtc acagataaag
     9661 ccccctctat tacaagtgcc tttaagaaac taaaagaata cggcttttat caagggacag
     9721 aacatcgtac cattaaatac ctgaataatt tgattgaaca agaccatcgt ccagtaaaga
     9781 gacgcaataa attctatcga agtttacgca ctgcctctac cacgattaaa ggcatggaag
     9841 ccattcgagg attatataag aaaacccgaa aagaaggcac tctcttcggg ttttcggtct
     9901 gtactgaaat caaggtatta ttgggaatcc cagcttaaat catagatacc gtaagggatt
     9961 ttattcttta tttaaaactt tgcaacagaa ccatttatag agtacagaaa acattttctg
    10021 tactctattt tgtcttcttt taaattttca atagattata tctattgtga attttgtaga
    10081 gggtcagaaa cttaatagtt tttgacacat aaacaaaatc gcgatataat ggggttgaga
    10141 gtgtttcata aacttatgtc ataaagttaa ggagatttcg catgatttta gagaataaat
    10201 tgggattaac caatcaagtt gagttggcta aggttgaaga aaaactcagt aaacaaaaag
    10261 cgaaagaatt gtacgattgt ggaaaaataa atgaaatcga agttggtaca tttaaaggtt
    10321 tatctgaaat tcatgaattt ctattttcgg atatttacga ttttgccgga aaaatccgat
    10381 cggtcaatat tgcaaaagga aattttcgat ttgcaccagt tatgtattta gaacattcgt
    10441 tacagcatat tgatcagatg ccacaaactt cttttgaaga gattatcaag aaatatgtgg
    10501 agatgaatat cgctcaccca tttcgagaag gaaatggccg aagtactaga atttggctgg
    10561 atctcatttt aaaggaagaa ttgcaaaaag ttgtagattg gaacttaatc gataaagcag
    10621 actatctttc tgcaatggag cgaagtccca taaacgattt ggaaatacgc tatctaattt
    10681 ccaatgctct gactgataaa attgacgatc gcgagttata tatgaaagga atcgatgtca
    10741 gctatttcta tgaagggtat tctgagtata cgatagatga tttgtaaaag taggtggacc
    10801 aaatgacgaa atatggatat gcacgtgtct caaccgcttc tcaaagtaca aaagaacaaa
    10861 ttcaacagtt gcttgagaac ggcgtagaga agaagaatat tttttcagaa aaatttacgg
    10921 gtacaaaacg ggatcggcca aaattcaatc agctgttggc tggtctgaag cctggagatg
    10981 aaatagttgt tacgaagctt gatcgatttg ctcgtaacac gagagaagca ttagagatca
    11041 ttgaaccttt actcgatgat aacgtaacga tcaaggtttt gaatctagga acgattgaaa
    11101 atacgtccat ggggcgaatg gtgacacgga cgttgttgag tgtagcagaa atggaacgtg
    11161 atatgattgt ggaacgtacc caagaaggaa aaatgtttgc aagaaagaat aatcctaatt
    11221 tcagagaagg acgtccgaaa gcaacaatca caccgaagaa gaggcacgca tatgaactgc
    11281 ttacttcagg taaatcgtat aaggaagttg aagctataac cggtttcagt cgcagtacgc
    11341 tttttagaat aaagaagaaa attgaagaaa gttaaaaaag aagtctcagc gaaccagaca
    11401 ggtaaatact taatgcgttc tagatatgag tctattagca tgttgtgaaa tataatattt
    11461 ttttatttac ttgatttctg ctcaaaaaat gtgtatggta actgtaaaag gtaaagtaat
    11521 taaaggtatg ctagccacgc ttactatatt aggataccat catatattta taatgaacga
    11581 tttgttcgtc taccaaacaa cacatatcgt tcagcgtaag tcacgtttag gaacgtggct
    11641 tttttagtgt tattatcgat aaataatcta ttgactctat tgattttatc tccatatccc
    11701 tacggtgttg attgtcttta gatctttcat ttaagaacca aataactatc ataaaaatca
    11761 gcactgctgc taaggttctg ttgcaaagtt ttaaataatt tgatttgtca aattaagcta
    11821 gacaaaatat cttcattcat gtaactcata aatacttcca ggggtgtttg ataatccaag
    11881 gactttcgtg gaatattgtt tctcttattc gccactgaag agataaaagc ttggtcgact
    11941 tgattaaaat ccatgttttt tggcagacca tcttttcgca gcaagccatt ggaattttca
    12001 ttcagtgctc gttgcgaagg agtccctgga tcagcgaaat aaatagcgat gtcatgttgg
    12061 ttacttaaag ccttccaatt agagaattct ttcccacaat caaaggtaat ggatttaaat
    12121 aaatgtctgg gaatcgatcc aaaccagtgg ttcagagtat tctcaatatc gatcgccttg
    12181 cgcccctcgg gcttcaaggt gatgatgatt ttcgatagac gttctaccaa agttatgaca
    12241 gcactcttat gatgaatgcc tacaatggta tcgccttcga tatggccgaa ctcttcttta
    12301 aatgtcgggt aatcagtttc tctttcaacg atattccgtt taaaagcctg ttttcctcgg
    12361 cgttcttgat gtccatttgg tttccgctta cccttcatgg gcaaagtcga ttcatcgaac
    12421 accttttcct tgaactggcg ataaagggtt cttacggaac agctgattgg tttctcttta
    12481 cgcccaatga taacgtctgg cgtccagcct tgggcaattt tttctttaat gtaggactgt
    12541 tgtttctttg gcaagacgat gtttcgtctg ccacaccgtt tcttattttc tttatactgt
    12601 tggtagtatt cgagggccgt atggccttct ttcaagaaat taatgacgtt ataaatcggt
    12661 gttcgagatc gtttcaggta ctcagcaatt ttcacaattt tgatgttttg gtggtagtaa
    12721 gactctatca tcaccagttc atccgtggta agatgggtgt aggtcattcg tgatcactcc
    12781 tatgttttct ttagtcggaa ttacattttg agtgtagcac gaatggctta tttatttgtc
    12841 tagcttaatt ttacaatcgg cgtaaagaat aaaatccctt acggtatcta tgatttaagc
    12901 tgggattccc aataatacct tgatttcagt acagaccgaa aacccgaaga gagtgccttc
    12961 ttttcgggtt ttcttatata atcctcgaat ggcttccatg cctttaatcg tggtagaggc
    13021 agtgcgtaaa cttcgataga atttattgcg tctctttact ggacgatggt cttgttcaat
    13081 caaattattc aggtatttaa tggtacgatg ttctgtccct tgataaaagc cgtattcttt
    13141 tagtttctta aaggcacttg taatagaggg ggctttatct gtgactacaa ccttcggttc
    13201 atcaaactgc ttcactaacc gcttaagaaa agcataggct gcttgtgtgt cccgtttttt
    13261 acgtaaccaa atatccaagg ttaaaccatc tgcatcgatg gctcgataca aataatgcca
    13321 ttttccttta attttgatgt acgtttcatc cattttccat gaataaaagg attttttatt
    13381 tttctttttc caaatttgat agagtagttt gccatattct tgcacccaac gataaatcgt
    13441 cgtatgagaa acgttaatgc cacgatcata taagatttct tgaacttcac gatagctaag
    13501 gttataacga agatagtagc ccacggctac aataatcaca tcctgctgaa attgctttcc
    13561 tttaaaatga ttcatcgtca ttcctcctgc tatctttttc tattattcta ccttatttga
    13621 tagtagattt aaaactttgc aacagaaccc ttccacctaa ttcattgagt acagaagaat
    13681 ccattaagca aggtgtgaag tatttcagtg aattattagc cagtagcgaa aggctcagtg
    13741 tagatttaga atcggttatc cagtcctaca attatggtgg tggtttctta gggtatgtgg
    13801 ctaatcgtgg aaataaatat acctttgaac tggctcaaag tttctcaaaa gagtattcag
    13861 gtggcgaaaa agtgtcttac cccaatccca tagccatacc tatcaatggg ggctggcgat
    13921 acaactatgg caatatgttt tatgtgcaac tggtaacgca gtatcttgtc acaacagagt
    13981 ttgatgatga tacggtacaa gccatcatgg acgaagcact gaaatatgag ggctggcgat
    14041 acgtttacgg tggagcttcc ccgactactt cttttgattg tagcggactg acacaatgga
    14101 cgtatggaaa agctggaatt aacttaccac gaaccgcaca acagcaatat gatgtgaccc
    14161 agcatatccc actatcggaa gcacaagctg gcgatttggt tttctttcat tctacctata
    14221 acgctggctc ttatattact catgttggga tataccttgg caataaccgt atgtttcatg
    14281 caggcgaccc aatcggttat gccgacttaa caagccccta ctggcaacag catttagtgg
    14341 gagcaggacg aatcaaacaa tgagaaagga agatttaatg atgaaattta gaaaaaatca
    14401 gaataaagaa aaacagatac caaaggaaaa gaaacctcgt gtctataagg tcaatcctca
    14461 taaaaaggtt gtgattgcct tgtgggtact tttagggctt agtttcagct ttgcgatatt
    14521 caagcacttt acagctatag atactcatac tattcacgaa acaactatca tagaaaagga
    14581 atacgttgat actcatcatg tagaaaattt tgtagagaac tttgcgaaag tctactattc
    14641 atgggagcaa tccgataagt ccattgataa tcgaatggaa agtctaaaag gctatctgac
    14701 agatgaactt caagctctca atgttgatac agtacgcaaa gatattcctg tatcgtcttc
    14761 tgtaagagga tttcagatat ggacggtaga gccaactggc gacaatgagt ttaatgtaac
    14821 ctacagtgta gaccagctca ttacagaggg agaaaataca aagaccgtcc actctgctta
    14881 tatagtgagt gtctatgtag atggttctgg aaatatggta ctggttaaga atccgaccat
    14941 taccaacata cctaagaaat caagttataa accaaaagcc attgaaagtg aggggacggt
    15001 tgattccatt acaaccaatg aaatcaatga gtttttaacg acgttcttca agctctatcc
    15061 tacagcgaca gccagtgaac tttcctacta tgtgaatgac gggatattaa aaccaatcgg
    15121 aaaagagtac atctttcaag aactggtaaa tcctattcac aatcgtaagg ataatcaagt
    15181 cacggtatcg ctgacagtgg agtatatcga ccagcagacc aaagcaacgc aggtatctca
    15241 atttgatttg gtacttgaaa agaacgggag taattggaag attgtaaaat aacaaatatt
    15301 ggtacatgat tacagatact ttgtaatcat gtactctttt tgataaaaaa ttggagattc
    15361 ctttacaaat atgctcttac gtgctattat ttaagtgact atttaaaagg agttaataaa
    15421 tatgcggcaa ggtattctta aataaactgt caatttgata gcaggaacaa ataattagat
    15481 gtcctttttt aggagggctt agttttttgt acccagttta agaatacctt tatcatgtga
    15541 ttctaaagta tccagagaat atctgtatgc tttgtatacc tatggttatg cataaaaatc
    15601 ccagtgataa aagtatttat cactgggatt tttatgccct tttgggtttt tgaatggagg
    15661 aaaatcacat gaaaattatt aatattggag ttttagctca tgttgatgca ggaaaaacta
    15721 ccttaacaga aagcttatta tataacagtg gagcgattac agaattagga agcgtggaca
    15781 aaggtacaac gaggacggat aatacgcttt tagaacgtca gagaggaatt acaattcaga
    15841 caggaataac ctcttttcag tgggaaaata cgaaggtgaa catcatagac acgccaggac
    15901 atatggattt cttagcagaa gtatatcgtt cattatcagt tttagatggg gcaattctac
    15961 tgatttctgc aaaagatggc gtacaagcac aaactcgtat attatttcat gcacttagga
    16021 aaatggggat tcccacaatc ttttttatca ataagattga ccaaaatgga attgatttat
    16081 caacggttta tcaggatatt aaagagaaac tttctatgga aattataatc aaacagaaag
    16141 tagagctgca ccctaatatg tgtgtgatga gctgtacgga acctgagcaa tgggatgtgg
    16201 taatagaagg aaatgatgac cttttagaga aatatatgtc cggtaaatca ttagaagcat
    16261 tagaactcga acaagaggaa atcagaagat ttcagaattg ctccttgtac cctgtttatc
    16321 atggaagcgc aaaaagcaac atagggattg agcagcttat agaagtgata acgaataaat
    16381 tttattcatc aacatacaga aagaagtctg aactttgcgg aaatgtcttc aaaattgaat
    16441 attcggaaga aagacaacgt cttgcatatg tacgccttta tggcggaatc ctgcatttgc
    16501 gggattcggt tagaatatcg gaaaaggaaa aaataaaaat tacagaaatg tatacttcaa
    16561 taaatggtga attatgtaaa attgataagg cttattccgg ggaaattgtt attttgcaaa
    16621 atgagttttt gaagctaaat agtgttcttg gagatacaaa gctattgcca cagagagaga
    16681 gaattgaaaa tccgctccct ctgctgcaaa caactgttga accgagcaaa cctcaacaaa
    16741 gggaaatgtt acttgatgca cttttagaaa tctccgacag tgacccgctt ctacaatatt
    16801 atgtggattc tacgacacat gaaattatac tttctttctt agggaaagta caaatggaag
    16861 tgattagtgc actgttgcaa gaaaagtatc atgtggagat agaactaaaa gagcctacag
    16921 tcatttatat ggagagaccg ttaaaaaatg cagaatatac cattcacatc gaagtgccgc
    16981 caaatccttt ctgggcttcc attggtttat ctgtatcacc gcttccgttg ggaagtggaa
    17041 tgcagtatga gagctcggtt tctcttggat acttaaatca atcatttcaa aatgcagtta
    17101 tggaagggat acgctatggt tgcgaacaag gattatatgg ttggaatgtg acggattgta
    17161 aaatctgttt taagtatggc ttatactata gccctgttag taccccagca gattttcgga
    17221 tgcttgctcc tattgtattg gaacaagtct taaaaaaagc tggaacagaa ttgttagagc
    17281 catatcttag ttttaaaatt tatgcgccac aggaatatct ttcacgagca tacaacgatg
    17341 ctcctaaata ttgtgcgaac atcgtagaca ctcaattgaa aaataatgag gtcattctta
    17401 gtggagaaat ccctgctcgg tgtattcaag aatatcgtag tgatttaact ttctttacaa
    17461 atggacgtag tgtttgttta acagagttaa aagggtacca tgttactacc ggtgaacctg
    17521 tttgccagcc ccgtcgtcca aatagtcgga tagataaagt acgatatatg ttcaataaaa
    17581 taacttagtg tattttatgt tgttatataa atatggtttc ttgttaaata agatgaaata
    17641 ttttttaata aagatttgaa ttaaagtgta aaggaggaat taattatgaa gtgaaatgaa
    17701 tgtaacaggg ttcaattaaa agagggaagc gtatcattaa ccctataaac tacgtctgcc
    17761 ctcattattg gagggtgaaa tgtgaataca tcctattcac aatcgaattt acgacacaac
    17821 caaattttaa tttggctttg cattttatct ttttttagcg tattaaatga aatggttttg
    17881 aacgtctcat tacctgatat tgcaaatgat tttaataaac cacctgcgag tacaaactgg
    17941 gtgaacacag cctttatgtt aaccttttcc attggaacag ctgtatatgg aaagctatct
    18001 gatcaattag gcatcaaaag gttactccta tttggaatta taataaattg tttcgggtcg
    18061 gtaattgggt ttgttggcca ttctttcttt tccttactta ttatggctcg ttttattcaa
    18121 ggggctggtg cagctgcatt tccagcactc gtaatggttg tagttgcgcg ctatattcca
    18181 aaggaaaata ggggtaaagc atttggtctt attggatcga tagtagccat gggagaagga
    18241 gtcggtccag cgattggtgg aatgatagcc cattatattc attggtccta tcttctactc
    18301 attcctatga taacaattat cactgttccg tttcttatga aattattaaa gaaagaagta
    18361 aggataaaag gtcattttga tatcaaagga attatactaa tgtctgtagg cattgtattt
    18421 tttatgttgt ttacaacatc atatagcatt tcttttctta tcgttagcgt gctgtcattc
    18481 ctgatatttg taaaacatat caggaaagta acagatcctt ttgttgatcc cggattaggg
    18541 aaaaatatac cttttatgat tggagttctt tgtgggggaa ttatatttgg aacagtagca
    18601 gggtttgtct ctatggttcc ttatatgatg aaagatgttc accagctaag tactgccgaa
    18661 atcggaagtg taattatttt ccctggaaca atgagtgtca ttattttcgg ctacattggt
    18721 gggatacttg ttgatagaag aggtccttta tacgtgttaa acatcggagt tacatttctt
    18781 tctgttagct ttttaactgc ttcctttctt ttagaaacaa catcatggtt catgacaatt
    18841 ataatcgtat ttgttttagg tgggctttcg ttcaccaaaa cagttatatc aacaattgtt
    18901 tcaagtagct tgaaacagca ggaagctggt gctggaatga gtttgcttaa ctttaccagc
    18961 tttttatcag agggaacagg tattgcaatt gtaggtggtt tattatccat acccttactt
    19021 gatcaaaggt tgttacctat ggaagttgat cagtcaactt atctgtatag taatttgtta
    19081 ttactttttt caggaatcat tgtcattagt tggctggtta ccttgaatgt atataaacat
    19141 tctcaaaggg atttctaaat cgttaaggga tcaactttgg gagagagttc aaaattgatc
    19201 ctttttttat aacaggaatt caaatctttt tgttccatta aagggcgcga ttgctgaata
    19261 aaagatacga gagacctctc ttgtatcttt tttattttga gtggttttgt ccgttacact
    19321 agaaaaccga aagacaataa aaattttatt cttgctgagt ctggctttcg gtaagctaga
    19381 caaaacggac aaaataaaaa ttggcaaggg tttaaaggtg gagatttttt gagtgatctt
    19441 ctcaaaaaat actacctgtc ccttgctgat ttttaaacga gcacgagagc aaaacccccc
    19501 tttgctgagg tggcagaggg caggtttttt tgtttctttt ttctcgtaaa aaaaagaaag
    19561 gtcttaaagg ttttatggtt ttggtcggca ctgccgacag cctcgcagag cccaccttta
    19621 cgaagtaaag tatagtgtgt tatactttac atggaagttg taccgaaata ttgtgttgtg
    19681 aagtctatat aattttaaaa ttatgaagtc tatatacgtg cgtaaagata tttaaagaga
    19741 ttaaaaataa taaaaataaa aattgaatta aaaagagata tggttgatta ttggaacgat
    19801 tgttttaatg atttacatat attacaacca gattggaaaa ctatcgaacg tacttctgat
    19861 agagcaatgg tttttatgtt gttgaatgat gaagaagaat ggggaaaatt agaaagacgt
    19921 actaagaata aatataaaaa attaattaaa gaaatatctc taattgattt aactgattta
    19981 atgaaatcga ctttaaaagc gaacgaaaaa caattgcaaa agcagattga tttttggcaa
    20041 cgtgaattta gattttggaa gtaaagtaac tttgttttat acaaaatgtt actttagtat
    20101 aattaacgtt taagaggtga cacaatatat gaaaaaatca gaggattatt cctcctaaat
    20161 acaaagagat aagatgaaat ttaggaggaa aattatatat gacttttaat attattaatt
    20221 tggaaacttg ggatagaaaa gaatatttta atcattattt caatcaacaa acaacttaca
    20281 gtgttactaa agaatttgat atcactttac ttaaaagtat gataaaaaat aaaggatatg
    20341 aactgtatcc tgctttgatt tatacaattg taaatattat aaatcaaaat aaagtattta
    20401 gaacaggaat taatagtgag ggaaatttgg gttattggga aaaattaaac cctttatata
    20461 cagtctttaa taaagaaact gaaaaatttt ctaacatttg gacagaatca aatgttagtt
    20521 ttaattcttt ttataatagt tataagagtg acttacttga atataaagat aaaaatgaaa
    20581 tgtttcctaa aaaaccaata cctgaaaaca cagttcctat ttcgatgatt ccttggattg
    20641 attttagttc atttaattta aatattggta ataatagtag attcctattg ccaattatta
    20701 caataggtaa attttatagt aagaataata agatctattt accagtctca ttgcaagttc
    20761 atcatgcggt atgtgatggt taccatgttt cattatttat gagtgaattt caaaatatag
    20821 ttgatagtgt aaatgaatgg atttaaatct aaaataactt tcataaactt aagtaattat
    20881 gatatttata agtttatagc aactaccatt tttggttgct ggtgttttga ttttgaattt
    20941 ggttttgaac ttatggactg atttattcag tccatttttt gtgcttgcac aaaaactagc
    21001 ctcgcagagc acacgcatta atgacttatg aaacgtagta aataagtcta gtgggttata
    21061 ctttacatgg aagttgtgcc gaagttagga gtgtttacat gtcatttgca gtggcgagaa
    21121 tgcagaaggt aaaatcagga aatttagtcg gggtaggtaa tcataatcag agaaatacag
    21181 acaatcattc caacaaagat attgatgttg aacggtcgca tttaaattat gatttggtca
    21241 atcggacaga aaattataaa cgagatattg agcaatttat taacgacaat aaatcaagta
    21301 gtcgtgctgt cagaaaagat gctgtattaa taaacgaatg gatcataact tctgacaacc
    21361 cattttttaa agataaagac gataaagaaa ttaaagattt ttttgatact gcgaaatcat
    21421 attttgcgga caaatttggc gataataata tccgctacgc tcaagttcac ttagacgaaa
    21481 cgacaccgca tatgcactta ggaattgtgc cgtttaatga cgaacacaag ctatcagcaa
    21541 agactgtttt taatcgtcaa gccttacaag cggtacaaga cgaattgcca aagtatttaa
    21601 atgagcgtgg ttttgagctt gaacgtggcg aaaaagggtc agagcgtaaa aatttaacgg
    21661 tgcctgaata taaaaaggca aaggacgaat taaaagagat aactaccacg ctggaacagc
    21721 gaaagtcaga agttttagcg ttatcgaacg ataaagcacc aacaatcaag aaagaaagtt
    21781 tagatttaaa agacgaaacg aaaacggtca aagtaccaag tggcgaaacc attgggattg
    21841 gtaagctgcg acatgaattt atgaaaaatg aagaacgaaa aacgggaaat gtaattatcc
    21901 ctgaaagtaa attaaatgca gtgattaaaa gctatgaaga gctatataaa gcaaatgaaa
    21961 agctaaaaaa ttatgcggaa actgatttac ctaaagaaat cactagagtt aaagagaaat
    22021 atcgcgaatt agcgaaagat tacaataggt tggtacgtaa gagtaatcag aatattgaaa
    22081 cacttgaaga attagagaaa gagaataagt cgcttaaaaa cgaaattaag ggcatttaca
    22141 aaggttttaa ccagtttatg gaaaataccc ttggtgcaac tgttggacaa gctaaaaagc
    22201 tgatgaataa ccttatgagc gaagttaaag agtttgtaaa aggtggagag tttgaaaaaa
    22261 ttcatagaaa cgaaactaaa acacgagata gggatgaatt aagtcgttag aagctcatat
    22321 ttgcgttcta agcgcttttt tatcaaaact agggtaattc tgcatattgt ttacttttcg
    22381 tcggcaaatg cgtaaaaaac agcgaaataa aagaggtcaa gggcgaacgt agtgagtgta
    22441 tttacccttg atctcttttt ttgagttgtt tagcttttgc taagacgacg gaaagaaacg
    22501 aatgcagtta tcaagttgct tttcagaggc aaggtcaagc gctttgcgct tgttgggtgt
    22561 gggcgaatag cccacggttt tattatttgg aaatttagtg ggagcagggg gcgaaaaaac
    22621 atgggaattt ttggagcgaa aaaacatggg ggcactacga caccccccat gtgtccattg
    22681 tccattgtcc aaatagataa aaagattaaa tgtcttgtaa atacctttat atgaacgttt
    22741 taagcaccta tttcgaggtg aaaaaaagtt ttttgtaaaa tcttgtattc ctgtcgtatg
    22801 tataatataa ttacagtgta aaagagattt tgaagagaat tgaggtgcat tttgtggttg
    22861 aagttgagaa gaaaaaagtg actttatctt tacctgttga atcgaatgac aaactagaaa
    22921 aaatggcaca aaaatatgga atgactaaat caggtttggt tacattttta attaatcaag
    22981 ctgatgataa ggggactatt tttaaataaa aaaagccctg ctaggaagat agcaagggct
    23041 cgcaagattt ggttttcttt gatttcgcaa ctcaagttta tcaaattttc ccttgttttc
    23101 ctagtagagt aactaggaag gtgtagaaaa atatggaaaa tgaaaataga acagattgga
    23161 cattgcctag aaagaattta aatccaaaaa ctaaacagcc ttataagcga ggtcgtaact
    23221 ggtggattgt tgtttatcct gaaagtttgc cagagaattg gaaagagatt atttcaactg
    23281 aacctgtggc aattagtcca ttacatgata aagatgttaa tgcagacgga acaaagaaaa
    23341 agccgcatta tcatatagtt tttaattaca agggcaataa atcatttgaa caaatggacg
    23401 aaatggcaag agttttaagg gcaccgattc ctgaaagaat aagtggttta actggtgctg
    23461 ttagatattt aacgcatatg gataatcctg aaaagtatca atacgataat acagaaatac
    23521 aagtgtttgg tggattcgac cttgaaagtt gtttagcgtt atctactggt gataaaagac
    23581 aagcgttaaa agaaatgctt ggttttattt cggataacaa tattatgcat ttaaaggttc
    23641 tgttgcaaag ttttaaataa agaataaaat cccttacggt atctatgatt taagctggga
    23701 ttcccaataa taccttgatt tcagtacaga ccgaaaaccc gaagagagtg ccttcttttc
    23761 gggttttctt atataatcct cgaatggctt ccatgccttt aatcgtggta gaggcagtgc
    23821 gtaaacttcg atagaattta ttgcgtctct ttactggacg atggtcttgt tcaatcaaat
    23881 tattcaggta tttaatggta cgatgttctg tcccttgata aaagccgtat tcttttagtt
    23941 tcttaaaggc acttgtaata gagggggctt tatctgtgac tacaaccttc ggttcatcaa
    24001 actgcttcac taaccgctta agaaaagcat aggctgcttg tgtgtcccgt tttttacgta
    24061 accaaatatc caaggttaaa ccatctgcat cgatggctcg atacaaataa tgccattttc
    24121 ctttaatttt gatgtacgtt tcatccattt tccatgaata aaaggatttt ttatttttct
    24181 ttttccaaat ttgatagagt agtttgccat attcttgcac ccaacgataa atcgtcgtat
    24241 gagaaacgtt aatgccacga tcatataaga tttcttgaac ttcacgatag ctaaggttat
    24301 aacgaagata gtagcccacg gctacaataa tcacatcctg ctgaaattgc tttcctttaa
    24361 aatgattcat cgtcattcct cctgctatct ttttctatta ttctacctta tttgatagta
    24421 gatttaaaac tttgcaacag aaccttttgt acatttaact tgacggtgac atctctctat
    24481 tgtgagttat tagtggtaca gttttcaacc gttttaatta taaaaaagtg gtgcattttt
    24541 aaattggcac aaacaggtaa cggttattgc aggtgtattt cttatctatg ggtttaacat
    24601 ggattttatc attaaaatca tgagtattgt ccgagagtga ttggtcttgc gtatggttaa
    24661 ccctaaagtt atggaaataa gacttagaag caaacttaag agtgtgttga tagtgcatta
    24721 aaaattttgt ataataggaa ttgaagttaa attagatgct aaaaatttgt aattaagaag
    24781 gagggattcg tcatgttggt attccaaatg cgttatgtag ataaaacatc tactgttttg
    24841 aaacagacta aaaacagtga ttacgcagat aaataaatac gttagattaa ttcctaccag
    24901 tgactaatct tatgactttt taaacagata actaaaatta caaacaaatc gtttaacttc
    24961 tgtatttgtt tatagatgta atcacttcag gagtgattac atgaacaaaa atataaaata
    25021 ttctcaaaac tttttaacga gtgaaaaagt actcaaccaa ataataaaac aattgaattt
    25081 aaaagaaacc gataccgttt acgaaattgg aacaggtaaa gggcatttaa cgacgaaact
    25141 ggctaaaata agtaaacagg taacgtctat tgaattagac agtcatctat tcaacttatc
    25201 gtcagaaaaa ttaaaactga atactcgtgt cactttaatt caccaagata ttctacagtt
    25261 tcaattccct aacaaacaga ggtataaaat tgttgggagt attccttacc atttaagcac
    25321 acaaattatt aaaaaagtgg tttttgaaag ccatgcgtct gacatctatc tgattgttga
    25381 agaaggattc tacaagcgta ccttggatat tcaccgaaca ctagggttgc tcttgcacac
    25441 tcaagtctcg attcagcaat tgcttaagct gccagcggaa tgctttcatc ctaaaccaaa
    25501 agtaaacagt gtcttaataa aacttacccg ccataccaca gatgttccag ataaatattg
    25561 gaagctatat acgtactttg tttcaaaatg ggtcaatcga gaatatcgtc aactgtttac
    25621 taaaaatcag tttcatcaag caatgaaaca cgccaaagta aacaatttaa gtaccgttac
    25681 ttatgagcaa gtattgtcta tttttaatag ttatctatta tttaacggga ggaaataatt
    25741 ctatgagtcg cttttgtaaa tttggaaagt tacacgttac taaagggaat gtagataaat
    25801 tattaggtat agggcacctc taataactac caattaattc acctcaaaat gaaattagaa
    25861 aaaaacagcg aaatttttaa atctatttct tatcgataca aattcctcgt aggcgctcgg
    25921 gaccccaaca tgaggaaatg tttttataaa aaaagagtag ttaccgtt
//
