LOCUS       NZ_AP024951            29020 bp    DNA     circular CON 30-JAN-2024
DEFINITION  Aeromonas caviae strain KAM345 plasmid pKAM345_3, complete sequence.
ACCESSION   NZ_AP024951
VERSION     NZ_AP024951.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMD00294561
            Assembly: GCF_019972775.1
KEYWORDS    RefSeq.
SOURCE      Aeromonas caviae
  ORGANISM  Aeromonas caviae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Aeromonadales;
            Aeromonadaceae; Aeromonas.
REFERENCE   1
  AUTHORS   Maehana,S., Suzuki,M. and Kitasato,H.
  TITLE     Draft genome sequence of carbapenem-resistant Aeromonas spp. in
            Japan
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 29020)
  AUTHORS   Maehana,S., Suzuki,M. and Kitasato,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-JUL-2021) Contact:Shotaro Maehana Kitasato university,
            Allied Health Sciences; 1-15-1, Kitasato, Minami-ku, Sagamihara,
            Kanagawa 252-0373, Japan URL
            :https://www.kitasato-u.ac.jp/ahs/english/index.htmltmRNA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.8.0
            Genome Coverage                   :: 193x
            Sequencing Technology             :: Illumina HiSeq X; ONT MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/30/2024 10:21:22
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,616
            CDSs (total)                      :: 4,457
            Genes (coding)                    :: 4,339
            CDSs (with protein)               :: 4,339
            Genes (RNA)                       :: 159
            rRNAs                             :: 11, 10, 10 (5S, 16S, 23S)
            complete rRNAs                    :: 11, 10, 10 (5S, 16S, 23S)
            tRNAs                             :: 122
            ncRNAs                            :: 6
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 30 of 118
            Pseudo Genes (incomplete)         :: 89 of 118
            Pseudo Genes (internal stop)      :: 12 of 118
            Pseudo Genes (multiple problems)  :: 10 of 118
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AP024951.1.
            Annotated at DFAST https://dfast.nig.ac.jp/
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..29020
                     /organism="Aeromonas caviae"
                     /mol_type="genomic DNA"
                     /strain="KAM345"
                     /db_xref="taxon:648"
                     /plasmid="pKAM345_3"
                     /geo_loc_name="Japan:Kanagawa"
                     /collection_date="2018"
     gene            join(28044..29020,1..352)
                     /locus_tag="LDN68_RS22810"
     CDS             join(28044..29020,1..352)
                     /locus_tag="LDN68_RS22810"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003286298.1"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="WP_202212047.1"
                     /translation="MEGFWLQWLGILGEIDKPDGLGYLLVMLFPAFLLLEVPLSLVILL
                     GVLRWFVRKPFELPEGNSYQPRVSCVITCYSEGRDVQTTLLSLCEQTYRGEIEMIPVVD
                     GATANHATMQAVRDFRLDAQLYPRRFLRPIAKWQRGGRVSSLNAGLEYSTGEIVMALDG
                     DTSFDNDMVVNVVRHFQDPDVPAVAGSLRVRNARASLTTAMQALEYLLSIQLAKIGLSE
                     WNVVNNVSGAFGAFRRSFLQKIGGWDTHTAEDLDITLRIKNYFGRRPLRIPFEPRAIGH
                     TDAPVTFRQFLMQRLRWDGDLFFLYVRKHRHSFTPRLLGWPNFLVVLVSGFFFQLVLPF
                     IILGYFIVGLYSLTLSTFLVLAWLVYLVYLANTLLAYVVAVCMVSERPRQDLWLCWVVP
                     LFPLFMFVMRCWSAVAILNEMIRRGHEETSMAPWWVLRKAKRF"
                     /name="glycosyltransferase"
     gene            352..2436
                     /locus_tag="LDN68_RS22815"
                     /old_locus_tag="KAM345_044250"
     CDS             352..2436
                     /locus_tag="LDN68_RS22815"
                     /old_locus_tag="KAM345_044250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003286296.1"
                     /GO_function="GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="WP_202212046.1"
                     /translation="MRRVFLLLGLLGLASSCLAEVLPLPALLDGANSTPLLRAAEAEGA
                     ALEALQRQREAEAGWQWFASAGIGRYRELVTEEVRDDYYGRDLALGLRHPLLGSLKRQQ
                     DALRSVEDQRQQQQARLQLARLEQRLALRSAYADWWRAQEELRWCDGIAEPARRAREQL
                     AARLREGWLLASEARLQDGRWQALERRCAAAGPLLEETRYSLQSLSGQTIEPQSQAQTE
                     ALAASAQPLSAWLQQLERHPRLQERRGQLRQAERNRQSPWYAAVDLSFSVAQSYEDRSG
                     GNEPGNGLVASISLSAPFDPLSYGQARGDEGAARHQMALAQLDAERERLVQGLGQALRA
                     QRAAAEDLLQARQQLEAAALAVREQRLRRAGDVDQAYLGSLAAELEHGYAGLRLIAAWH
                     GLWLREAALRLFVDDDVAHAPLLGPATLDWQAPVAAAHTAAAPRAVQWQQGVYLWDSHA
                     LLDEQRRAEALAQLRAAGMQRLYLGLDAAQVAEPERLRGQLRVLLSAAREQGFEVLLLL
                     GDPHWLQPEGRQGLLDLLGELTTLPFAGLHLDLEVEQLGWPVPEARLRDWMDTLTAAAS
                     VSPWPLELSSHHRWFAAPRAGEYCVPCELRQRGVRQVSLMIYTRNAARSAELAADIARR
                     WPGLSFRLAQSVEPQLAADESWSAASRAQLQAQTERWRQQLQPQAVAGIDWQDWSHYPH
                     "
                     /name="TolC family protein"
     gene            2446..3462
                     /locus_tag="LDN68_RS22820"
                     /old_locus_tag="KAM345_044260"
     CDS             2446..3462
                     /locus_tag="LDN68_RS22820"
                     /old_locus_tag="KAM345_044260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013984346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family efflux transporter periplasmic
                     adaptor subunit"
                     /protein_id="WP_202212045.1"
                     /translation="MKIKFSSAKEQQPTQEQGLQVLYAPGKRLAFRVRWYLILLAVLSP
                     LLWLIGRWVLTLWLIEAPAQLHLPGSELRARDAAQVQQLLVQPGQRVTAGELLVRLDNS
                     EWRARRFLLEAASTPMESPNAASLAAERALLQESLAGAEARVRQVQRLLDAGAATRGEL
                     LAATDLRDVRLRELYQLEQRRQPDAGPEQRQRDLELAWLDSRLQGLELRAENDGRVGEI
                     LVAPGENVGPGTPLLRVESDGEAQVWVYLDPRHAAEATPGKLLTLIFPDHSQRQAVVIQ
                     AVDDAAPVPVELRPPFSAPTRRLRVIARVHDGLPPEWRIDRLGLKARFPHRWLPFGG"
                     /name="HlyD family efflux transporter periplasmic adaptor
                     subunit"
     gene            complement(3469..>3891)
                     /locus_tag="LDN68_RS22825"
                     /old_locus_tag="KAM345_044270"
                     /pseudo=""
     CDS             complement(3469..>3891)
                     /locus_tag="LDN68_RS22825"
                     /old_locus_tag="KAM345_044270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013984345.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /name="hydrolase"
     gene            complement(3955..>4272)
                     /locus_tag="LDN68_RS22830"
                     /old_locus_tag="KAM345_044280"
                     /pseudo=""
     CDS             complement(3955..>4272)
                     /locus_tag="LDN68_RS22830"
                     /old_locus_tag="KAM345_044280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013721910.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /name="integrase"
     gene            complement(4338..4913)
                     /locus_tag="LDN68_RS22835"
                     /old_locus_tag="KAM345_044290"
     CDS             complement(4338..4913)
                     /locus_tag="LDN68_RS22835"
                     /old_locus_tag="KAM345_044290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009602860.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001173919.1"
                     /translation="MALIGYARVSTAEQDTALQTDALRNAGCERVFEDTASGAKADRPG
                     LADALAYLRDGDVLVVWRLDRLGRSLPHLIETVGKLEARGVGFRSLTENIDTTTPGGRL
                     IFHVFGALGQFERDLIRERTKAGLTAAAARGRKGGRKPVVTADKLQRARELVANGLNVR
                     EAAARLKVGKTALYAALQAASSGSAADS"
                     /name="recombinase family protein"
     gene            complement(5040..5288)
                     /locus_tag="LDN68_RS22840"
                     /old_locus_tag="KAM345_044300"
     CDS             complement(5040..5288)
                     /locus_tag="LDN68_RS22840"
                     /old_locus_tag="KAM345_044300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012585400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family toxin"
                     /protein_id="WP_012585400.1"
                     /translation="MQSSIERTVSGVRCTNDDLKPVLVALATDQPLDVRYRDHDLSGDW
                     AGYRECHIKPDLLLIYRKSDADTLRLARLGSHSELFG"
                     /name="type II toxin-antitoxin system YafQ family toxin"
     gene            complement(5568..5846)
                     /locus_tag="LDN68_RS22845"
                     /old_locus_tag="KAM345_044310"
     CDS             complement(5568..5846)
                     /locus_tag="LDN68_RS22845"
                     /old_locus_tag="KAM345_044310"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_202211495.1"
                     /translation="MSGDDKQLELEALAAVGEMLLFDQARGNPEEAARILRCARLFARS
                     EDAAQRLSELCNEAGSDATWRENIVEELQDREDLQAAEAAMEARRQA"
                     /name="hypothetical protein"
     gene            complement(5843..6163)
                     /locus_tag="LDN68_RS22850"
                     /old_locus_tag="KAM345_044320"
     CDS             complement(5843..6163)
                     /locus_tag="LDN68_RS22850"
                     /old_locus_tag="KAM345_044320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013124593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BrnA antitoxin family protein"
                     /protein_id="WP_045286807.1"
                     /translation="MPTKESNIVKRTLDLKKPPQLSAEQKARLDAVASMPDEQIDYSDA
                     PYLPDAVWMKAAEQLPHTKKQITLRIDAEVLEFFKHTGKRYQSRMNAVLRSYVEAHKAH
                     AK"
                     /name="BrnA antitoxin family protein"
     gene            complement(6123..6401)
                     /locus_tag="LDN68_RS22855"
                     /old_locus_tag="KAM345_044330"
     CDS             complement(6123..6401)
                     /locus_tag="LDN68_RS22855"
                     /old_locus_tag="KAM345_044330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013124592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BrnT family toxin"
                     /protein_id="WP_015060221.1"
                     /translation="MELEWDADKAARNLKKHGVSFEDAELVFYDSGRVEAYDGREDYGE
                     DRWATIGLAYSAVLYVVYTVRHEETIRLISARKANADERKQYREANS"
                     /name="BrnT family toxin"
     gene            complement(6443..9115)
                     /gene="traI"
                     /locus_tag="LDN68_RS22860"
                     /old_locus_tag="KAM345_044340"
     CDS             complement(6443..9115)
                     /gene="traI"
                     /locus_tag="LDN68_RS22860"
                     /old_locus_tag="KAM345_044340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018413464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraI/MobA(P) family conjugative relaxase"
                     /protein_id="WP_059385972.1"
                     /translation="MIVKKVKNPQKAASKAVRVSRLTDYIREPERENSQEKCIHAGARG
                     FITDEPQSQTAEMIALSQEAVRSKDTINHYVLSWREGEQPSPEQVEEAVSIFMDELGVK
                     DHQAIYGLHADTDNLHLHLAINRVHPETLKVVKINNGFDIEAAHKAIARIENAQGWQRE
                     QNGRYQVLENGELGREHIDKDKPRQPAQPKRDMENRTGEKSAERIAIEDGAPIIKKAQT
                     WEQLHRELAAKGMRYEKTGSGATLFVGDVGVKASSADRDASLSKLQKRLGAYQPPPQRQ
                     QVAQREPEPIKPDVPGWKDYITGRKAHYAEKNAAKLALDKRQEQERKQIAEQQKARRDE
                     LMRGNWKGKGEVLNAMRSVIAAEQAAEKAALKEKHQKQREQHRQQFRPYPDLEQWQRMQ
                     KSPELAEQWRHRASEPQRIEGASGEPPTPRDIRAYQPEIVGQQVHYSRKEEAGAGGGVS
                     FVDKGKSIDIHDWRNRDSTLAALQLSAQKWGSFTVTGNDEYKAMCAKLAAEHGFKITNP
                     ELQERIQQERQRIQQERAQAMKSEQLKQFELYAEAVGAERYRVTSIKMQADGRKQTFIL
                     DKKDGITRGFTPQEIEQRTPEMLRLQRRGENLYYTPLSDKKHHILIDDMNREKLERLIR
                     DGYRPAVVLESSPGNYQAIITVPKLGTAHDKDVGNRLSDALNREYGDPKLSGAIHPHRA
                     PGYENRKPKHQREDGSYPEVRLLKAERRECVKALALSSQIDAEYQRQAALKAQQPERSK
                     AKPALELAAASGSAIDAYQRHYRDVIKRQRGGEVDLSRVDSMIAVRMRVTGHDQAAIEG
                     AIRQCAPATRQKGEGRDWNDYAQRTARYAYSAAGDRQAAELGKYRQQWEKLEGREPVRQ
                     QEQAKAQKIERDNSPGMSR"
                     /name="traI"
     gene            complement(9096..9416)
                     /locus_tag="LDN68_RS22865"
                     /old_locus_tag="KAM345_044350"
     CDS             complement(9096..9416)
                     /locus_tag="LDN68_RS22865"
                     /old_locus_tag="KAM345_044350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014003869.1"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix protein, CopG family"
                     /protein_id="WP_021029055.1"
                     /translation="MPFETQGPEPLDAVINVRLTAAEKARLKEDADLAGLSMSELVRRR
                     YFGRPIIANADAVMLKELRRIGGLLKHIHNESGGIYNKDTAGALVALKAYIGKLSRDRQ
                     EG"
                     /name="ribbon-helix-helix protein, CopG family"
     gene            9726..10082
                     /locus_tag="LDN68_RS22870"
                     /old_locus_tag="KAM345_044360"
     CDS             9726..10082
                     /locus_tag="LDN68_RS22870"
                     /old_locus_tag="KAM345_044360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009873357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_015060219.1"
                     /translation="MKCTTEQLEAIAAKLREMPPVEKKKQEHSKQDAVRILSKEIALLQ
                     KRGYTLDQISETLRGEGLSIATPTLKSYLQRAKPAKKAPVQAPGDTPRPRPAVKKPADT
                     SKATFTPKPDSDDI"
                     /name="hypothetical protein"
     gene            10095..10778
                     /locus_tag="LDN68_RS22875"
                     /old_locus_tag="KAM345_044370"
     CDS             10095..10778
                     /locus_tag="LDN68_RS22875"
                     /old_locus_tag="KAM345_044370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018413461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mobilization protein"
                     /protein_id="WP_015060218.1"
                     /translation="MAKSIYLIGGSKGGVGKSLVTMATVDYLQERGESVLLIESDTSNP
                     DVWKAYKESTETELINLDEADGWIQLVNLCDSKPDSVVVINTAARNNKGVSAYGETLNS
                     TLEELKRKLVTLWVINRQRDSLELLKEYMDAIPNADVHVVRNGHFGEENKFELYNGSKL
                     RTAVEERGGKSVTFPDMADRVSDDIYSKRMSIAVALKELPIGNRAELTRWRNEAKKVLE
                     AVVHE"
                     /name="mobilization protein"
     gene            10771..11409
                     /locus_tag="LDN68_RS22880"
                     /old_locus_tag="KAM345_044380"
     CDS             10771..11409
                     /locus_tag="LDN68_RS22880"
                     /old_locus_tag="KAM345_044380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009873359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6753 family protein"
                     /protein_id="WP_009873359.1"
                     /translation="MSDLDDSFAKLLGRQPSDAERQSLYRVRDALGLKNNDALWLVLMA
                     LQHYQGQYEKFPQAIAQAAKDTLVNFKVTADATVKASAEAAKADLAQAVAAAAQEVAHN
                     TSAKQMWQWAAGCIAVAFLCVGLFGWYMHSSGKDSGYQAGYGAGYTEAKDEKAAAAWAN
                     TPEGRLAYRFAQTGSLASLAKCDRPGWYVEKGVCYVKPASDGTYGWRLP"
                     /name="DUF6753 family protein"
     gene            11406..11999
                     /locus_tag="LDN68_RS22885"
                     /old_locus_tag="KAM345_044390"
     CDS             11406..11999
                     /locus_tag="LDN68_RS22885"
                     /old_locus_tag="KAM345_044390"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="OfxX fusion product"
                     /protein_id="WP_223930628.1"
                     /translation="MRIKIKGEITAERLAEALHAAAEKYEAVRPGHKVYGANLYLTAFD
                     ADGLPFDLVDHRGEPLSITIEAKSGELVKPALTAEGEARRQKAKEEARRQAEEAEAEAQ
                     RRHRQTLDEYEQERQKRRKKEAEARKQFEDANAITAELLKTMPERFIDELNKTVQGVWG
                     DLKPTETQGKKKGQPKALPVFSVHADGLLLSVET"
                     /name="OfxX fusion product"
     gene            complement(12153..12980)
                     /locus_tag="LDN68_RS22890"
                     /old_locus_tag="KAM345_044400"
     CDS             complement(12153..12980)
                     /locus_tag="LDN68_RS22890"
                     /old_locus_tag="KAM345_044400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020308987.1"
                     /GO_function="GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA]; GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="WP_059385974.1"
                     /translation="MPKTRKHLTPTEAEAKGLLCRKHLKERLRLMPGLNTKPAGSVWQG
                     QGAYDVYNPAECVPWRWMPGRAQVRRQHVAAQAKDLIAAGCIVLDTETTGLGDDAEICE
                     ITILDVTGAPILDTLVRPTRPIPVEATAIHKITDAMVASAPSWPEVAEQYAAAVAGRTV
                     VAYNVAFDARLLRQTYQIHGLTAPVLTTACAMLMYAEWHGEYDRSRDRWRWLKLIEAAT
                     DCGVAEDGAHRALADARMTLGVLRYLQRRTNGRRPAGPKVATVPQEALPSVLG"
                     /name="3'-5' exonuclease"
     gene            complement(13366..14277)
                     /locus_tag="LDN68_RS22895"
                     /old_locus_tag="KAM345_044420"
     CDS             complement(13366..14277)
                     /locus_tag="LDN68_RS22895"
                     /old_locus_tag="KAM345_044420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005796449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="WP_202212044.1"
                     /translation="MARQGITFEQVAAVADALAGEGQQPTIRAVREKLGDTGSPNTIHK
                     HLTAWREARPVAAAAAPELPQALTAAIAAEIERAASRARGEIEGRLVQAQAEAAELAAA
                     GEVLEGERDELAEQVAVLTTERDTLAGKAAQQATDLAEAQQRIEREQQAAESARLEVAT
                     ARHKIEAQAERVSEQAAELERLRAALAEAQQGRTAAEQQAAVLAAKLEACADRVSRAEA
                     RAEQIEQQAAKAAQAHDTARAAAAQETRQTQAERDEARKVAAEAREQAARLAGQLEALQ
                     RQQDKAEAAEKATKAPKGKGGE"
                     /name="DNA-binding protein"
     gene            complement(14820..15068)
                     /locus_tag="LDN68_RS22900"
                     /old_locus_tag="KAM345_044430"
     CDS             complement(14820..15068)
                     /locus_tag="LDN68_RS22900"
                     /old_locus_tag="KAM345_044430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008168813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_142875131.1"
                     /translation="MTVQETLDRLGLYWKRDPDFVPVKDKATVRLNVSIGGGGVELLAT
                     GPKWYDTRAEQGGGGAIDLTMHLFRLPFVDAVKRLSP"
                     /name="hypothetical protein"
     gene            complement(15262..>15869)
                     /locus_tag="LDN68_RS22905"
                     /old_locus_tag="KAM345_044440"
                     /pseudo=""
     CDS             complement(15262..>15869)
                     /locus_tag="LDN68_RS22905"
                     /old_locus_tag="KAM345_044440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018574828.1"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /name="replication protein"
     gene            complement(16220..16444)
                     /locus_tag="LDN68_RS22910"
                     /old_locus_tag="KAM345_044450"
     CDS             complement(16220..16444)
                     /locus_tag="LDN68_RS22910"
                     /old_locus_tag="KAM345_044450"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_202211496.1"
                     /translation="MVRLRLASGWPVSDDFVGFRAWESWRHGPRALEWRRVGAGRLCLT
                     ETAGGYRRITVASAIRAIEAEAEQHNHFG"
                     /name="hypothetical protein"
     gene            16644..17615
                     /locus_tag="LDN68_RS22915"
                     /old_locus_tag="KAM345_044460"
     CDS             16644..17615
                     /locus_tag="LDN68_RS22915"
                     /old_locus_tag="KAM345_044460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001255888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase domain-containing protein"
                     /protein_id="WP_202211497.1"
                     /translation="MARCDRAHPNARNFGLGSRDMGYAGLNALREGMQSHSSIATMADR
                     WSQFAAWAREAAGIRDMRQIVTDTLRGYADHLLTRLEQGEISPATAQNALSAVNRVLEI
                     ARGDRLVRLDPVHEAGLPIRSGIATTDRAVSLSQHDHAVATVSERVAAILSLQRAFGLR
                     FEEAAKLDAVRALAQAQHGMVRIEVGTKGGLARDVPITNPLEQKFLLANAANIQENARS
                     LIPAHQTYREFRAEAYAELRSAGIRSHGERHAYAQERYAALVGAPAPVAAGVAHGAAHH
                     RFLAVRLGLTVAAARALDQQARERVAAELGHGRLDVTNTYLG"
                     /name="integrase domain-containing protein"
     gene            17951..18193
                     /locus_tag="LDN68_RS22920"
                     /old_locus_tag="KAM345_044470"
     CDS             17951..18193
                     /locus_tag="LDN68_RS22920"
                     /old_locus_tag="KAM345_044470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005321398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid replication protein RepB"
                     /protein_id="WP_202211498.1"
                     /translation="MEELQAKWTFDQGGFAKALIVPTPMGQGYHLHLVKFGKQSETIFL
                     ERQRGGWRVFKSIDAAANTANGIGFRRIEIDLSSR"
                     /name="plasmid replication protein RepB"
     gene            18852..19496
                     /locus_tag="LDN68_RS22925"
                     /old_locus_tag="KAM345_044480"
     CDS             18852..19496
                     /locus_tag="LDN68_RS22925"
                     /old_locus_tag="KAM345_044480"
                     /inference="COORDINATES: protein motif:HMM:NF018691.4"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="WP_104456142.1"
                     /translation="MIVAVAHNKGGVGKTTTVVQLAGELKPEIIIDLDAHQGIAIINGR
                     RPAELRWDVRANLDKAALIKLLKAVGEHLVLIDCGGFDSELVRIAIAAADLIIAPSNDD
                     ITEQIGLVRFNRVLSEISQATGEPIQAHVLMTRTNPSRKNFAAISDELTRLPHLTMMTS
                     KLSRRADWANQMESGLGVTERAATRSSAAGMEAKALAEEVRSKLAMLTKQY"
                     /name="ParA family protein"
     gene            19531..19773
                     /locus_tag="LDN68_RS22930"
                     /old_locus_tag="KAM345_044490"
     CDS             19531..19773
                     /locus_tag="LDN68_RS22930"
                     /old_locus_tag="KAM345_044490"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_104456124.1"
                     /translation="MAKKLINLDDLGAGAPLKEVVTATDGSRGKIPTKAKNIQNMPLEF
                     FTRHAALREKGNTSLLFTAYIIEAVRKALEDDEQR"
                     /name="hypothetical protein"
     gene            complement(20284..21321)
                     /locus_tag="LDN68_RS22935"
                     /old_locus_tag="KAM345_044500"
     CDS             complement(20284..21321)
                     /locus_tag="LDN68_RS22935"
                     /old_locus_tag="KAM345_044500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200161.1"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="WP_182934362.1"
                     /translation="MTSVAKLIDRQDDIANGVAAPLGLPKFDTYAICNLRGGIGKTSLA
                     FNLSYYTDDLLVLDTCPQGNLSYFFDNNFLSSNSLSVNDLLMPYFVPGLGFATRVAKKI
                     SATNNFFASKNSYFIPSSSDLYILPTQIANALAQARLIAGPNQVSIIDNMLFSLKKEIS
                     REWGETETSKCLIDTSPFFSGATHLSWHAADALIVPVRTDQQSINSLELLLDTLSNPAS
                     EFRRVMPSNQHTPKIQMVVLTHCGWSTVPGAKNKPNNQTKVYLEKVRDIVSRNITHFTT
                     QDPDNHILLLDDFLGCGRMSSARSKPIELLNPGESMTINRVKATVNPSVMKIRQELKFI
                     SQNIW"
                     /name="ParA family protein"
     gene            22061..23638
                     /locus_tag="LDN68_RS22940"
     CDS             22061..23638
                     /locus_tag="LDN68_RS22940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001513488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing methyl-accepting chemotaxis
                     protein"
                     /protein_id="WP_001323889.1"
                     /translation="MRQNLPVTGRNLELPKDANILSTTSPQSHITYVNPDFIKISGFTE
                     EELLGQPHNIVRHPDMPPAAFEHMWSTLKSGRSWMGLVKNRCKNGDHYWVSAYVTPIAK
                     NGSIVEYQSVRTKPEPEQVLAAEKLYAQLRSGKAARPKLAASFSVKILLLIWGSIISSA
                     MAAGMLTDTSISSLLLATLMSGSLSSVSVLAILSPLGRLVERARNISNNPLSQSLYTGR
                     TDEFGQIEFALRMMQAETGAIVGRIGDASNRLSEHTRGLLKDIESSNVLTVEQQAETDQ
                     IATAVNQMVASIQEVASNAQHAADAAGRADTETASGQRLVAHTSQSITALEGEIRQATQ
                     VIHELEGQSNEISKVLDVIRGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLAA
                     RTQQSTTDIQSMISALQERAQSAVTVMEQSSRQAHTSVAHAEEAATALDGIGQRVNEIT
                     DMNAQIATAVEQQGAVSEDINRSIINIRDAADTNVQTGQNNLQSAKSVAQLTSALSELA
                     KQFWEKRG"
                     /name="PAS domain-containing methyl-accepting chemotaxis
                     protein"
     gene            complement(24599..24796)
                     /locus_tag="LDN68_RS22945"
                     /old_locus_tag="KAM345_044540"
     CDS             complement(24599..24796)
                     /locus_tag="LDN68_RS22945"
                     /old_locus_tag="KAM345_044540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005918372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid partition protein ParG"
                     /protein_id="WP_139731038.1"
                     /translation="MSVLKAGRPSSEKRAMTMGDIAGSVKMKRVNFDLPEALHTKLKMH
                     AAAQGKSIKDIMTDFVEALP"
                     /name="plasmid partition protein ParG"
     gene            complement(24817..25446)
                     /gene="parA"
                     /locus_tag="LDN68_RS22950"
                     /old_locus_tag="KAM345_044550"
     CDS             complement(24817..25446)
                     /gene="parA"
                     /locus_tag="LDN68_RS22950"
                     /old_locus_tag="KAM345_044550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017411316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family partition ATPase"
                     /protein_id="WP_202212049.1"
                     /translation="MLVISVLNQKGGSGKTTIATHLARAFQVAGRDVLLIDSDPQGSAR
                     DWSAVRDEQPVPVVGIDRPTIERDIKAVSHKDLIVIDGAPQAADLAISAIKASNLVLIP
                     VQPSPYDIWAASDLVDLVKQRIEMTDGRLKAAFVVSRAIKNTKIGAEIREALEGYGLPV
                     LAARVTQSVAYPSTAAAGTTVLDAEPNSNAAQEIRDLADEVLELLK"
                     /name="parA"
     gene            complement(25746..26030)
                     /locus_tag="LDN68_RS22955"
                     /old_locus_tag="KAM345_044560"
     CDS             complement(25746..26030)
                     /locus_tag="LDN68_RS22955"
                     /old_locus_tag="KAM345_044560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017411299.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_139731036.1"
                     /translation="MQVKWLRKAALNLEDAHDYLAKENPRVAQEFAHEVYRLVNLLVEQ
                     PSMGRSGRVPGTRELVVQPYPFLIPYRVKGEEIHILRVFHTRLRLPSHW"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(26020..26259)
                     /locus_tag="LDN68_RS22960"
                     /old_locus_tag="KAM345_044570"
     CDS             complement(26020..26259)
                     /locus_tag="LDN68_RS22960"
                     /old_locus_tag="KAM345_044570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005740683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family ribbon-helix-helix protein"
                     /protein_id="WP_042044878.1"
                     /translation="MSVMSVRLPDEVEQQLGQLAQSTGRTKSWLANQAIKDYLAREAWQ
                     ITEVEAALREADAGDFVSEKEMMAKFNRWGINAG"
                     /name="CopG family ribbon-helix-helix protein"
     gene            26660..28042
                     /locus_tag="LDN68_RS22965"
                     /old_locus_tag="KAM345_044580"
     CDS             26660..28042
                     /locus_tag="LDN68_RS22965"
                     /old_locus_tag="KAM345_044580"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013984349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="WP_202212048.1"
                     /translation="MPRVAVLGASSSPVVGIEYERHPEWSALAALPAYDIVLLDLPAVR
                     AGEALRSLRMDKRYRFSLIYCCQEQDASCKALSDGAPPADLSALVPLWRLWQERFALFN
                     RGVAPERFESRVLAWLWLHPHGAIHAVRDAGVAQHYHYPLLEALEDDESPNAFAWLQLM
                     TQQGWLEEGELVDRVRLCVGCGSGRLNYVDVCPECQTLEIARQPSLHCFTCGHVGAQEH
                     FLKDGLLLCPNCFSRLRHIGSDYDRPLENYRCRSCQAFFVDAEVEARCLDCGQAHAPDK
                     LRVREVRHFRLAEAGRLRCRQGYSASVAETDQFGALNLLNQKSFHELLNWQLQLVRRYK
                     QPAFSLLGLRFVNLAATISALGELRGHALVDSLVERLQEAVRDTDRCSRVSEEILWIMM
                     PHTDAAGLAVVRKRLQEGAERLASEQIGQLQLRQIGFTAPADLLEQEDAALLLARLNGE
                     LG"
                     /name="diguanylate cyclase"
     Typing          18012..18174
                     /name="rep_cluster_2037"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="89.634"
                     /coverage="87.0"
                     /evalue="8.2e-52"
     Typing          complement(6450..9115)
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="91.676"
                     /coverage="99.0"
                     /evalue="0.0"
ORIGIN
        1 ggtgctggtc agcgggttct tcttccagct ggtgctgccg ttcatcatcc tcggctactt
       61 catcgtcgga ctgtactcgc tgacgctgtc gaccttcctg gtgctcgcct ggctggtcta
      121 tctggtgtac ttggccaaca ccctgctggc ctacgtggta gcggtgtgca tggtgtccga
      181 gcggccgcgg caggacctgt ggctgtgctg ggtggtgccg ctgtttccgc tgttcatgtt
      241 cgtcatgcgc tgctggagcg cagtggcgat cctcaacgaa atgatccggc gtggccatga
      301 ggaaacctcg atggcgccct ggtgggtgct gcgcaaggcg aagaggttct gatgcggcga
      361 gtattcctat tgctgggtct gctgggactg gcttcatcct gtctggccga ggtattgccg
      421 ctaccggcgc tgctcgatgg cgccaacagc acgccgctgc tgcgcgcggc cgaggccgaa
      481 ggtgcggcgc tcgaggcatt gcagcgccag cgcgaggccg aagccggctg gcaatggttc
      541 gcctcggcag ggatcgggcg ctatcgggag ctggtgaccg aagaggtgcg cgacgactac
      601 tacggtcgcg atctggcgct cggcttgcgt catccactgc tgggcagcct gaagcgccag
      661 caggatgcgt tgcgcagcgt cgaagaccag cgccagcaac agcaggcgcg actgcagctg
      721 gcgcgcctcg agcagcgcct ggcactgcgc agcgcctatg ccgactggtg gcgagcgcag
      781 gaagaactgc gctggtgcga cggcatcgcc gagcctgcac ggcgcgcgcg cgagcagctg
      841 gcggcgcgcc tgcgcgaagg ctggttgctg gcttccgagg cgcgtctgca ggatggccgc
      901 tggcaggcgc tggagcgccg ttgcgccgcc gccgggccgc tgctggaaga aacccgctac
      961 agcctgcagt cgctgagtgg acagaccatc gagccgcaaa gccaggccca gaccgaagca
     1021 ctggcggcaa gcgcgcagcc tctgagcgcc tggttgcagc agctcgagcg gcatccacgt
     1081 ctgcaggagc ggcgcggcca gctgcgtcag gccgagcgca atcggcagag tccgtggtac
     1141 gcggcggtcg atttgagctt cagcgtcgcg cagagctacg aagaccgcag cggtggcaac
     1201 gagccgggca atgggctggt ggccagcatc agcctgtcgg cgcccttcga cccgctgtcc
     1261 tacgggcagg cgcgcggtga tgagggcgcg gcgcgtcacc agatggcgct ggcgcagctc
     1321 gatgccgagc gtgagcgcct ggtgcagggc ctcggccagg cactgcgtgc gcagcgcgcg
     1381 gccgccgaag acctgctgca ggcgcgccag cagttggaag cggcggcgct ggccgtgcgt
     1441 gagcagcgtc tgcggcgcgc tggcgacgtc gatcaggcct atctgggcag cctggcggcc
     1501 gagctggagc acggctacgc cgggctgcgc ctgatcgccg cctggcacgg gttgtggctg
     1561 cgggaagcgg ctctgcgcct gttcgtggac gacgatgttg cgcacgcgcc gttgctcggg
     1621 ccggccacgc tcgactggca ggcaccggtg gcggccgcac acacggcggc ggctccccgg
     1681 gcggtgcaat ggcaacaggg cgtctatctc tgggacagcc acgcactgct cgacgaacag
     1741 cgccgcgccg aggcattggc gcaactgcgc gcggccggca tgcagcgtct ctacctcggc
     1801 ctggacgccg cccaagtggc tgagccggag cgcttgcgcg gccagttgcg cgtgttgctc
     1861 agtgccgcgc gcgaacaggg attcgaggtg ctgctgctgc tcggcgatcc gcactggcta
     1921 caacccgagg gtcgtcaggg gttgctcgat ctgctcggtg agctgacgac gctgccgttc
     1981 gccggtctgc atctggatct ggaagtcgag cagctcggct ggccggtccc cgaggcgcgg
     2041 ctgcgcgact ggatggatac gctgacggcg gccgcgagcg tcagtccctg gccgcttgag
     2101 ctgtccagcc atcaccgctg gttcgccgca ccgcgcgccg gcgaatactg cgtcccctgc
     2161 gagctgcgcc agcgcggcgt gcgccaggtc agcctgatga tctacacccg caacgccgca
     2221 cgcagtgcgg agctggcggc ggatattgcg cgccgctggc cgggactgtc gttccgcctg
     2281 gcgcagagcg tggagccgca gctggcggcg gatgaaagct ggagcgccgc ctcgcgcgcg
     2341 caattgcagg cgcagaccga gcgctggcgc cagcagttgc agccacaggc cgttgccggc
     2401 atcgactggc aggactggtc tcactatccc cattgagcac attgcatgaa gatcaaattc
     2461 tccagcgcca aggagcaaca acccacccag gagcagggcc tgcaggtgct ctatgcgccg
     2521 ggcaagcgcc tggcctttcg agtgcgctgg tacctcattc tgctggcggt actcagtccg
     2581 ctgctttggc tgatcggccg ctgggtgctc acgctgtggc tgatcgaggc gccggctcag
     2641 ctgcatctgc cgggcagcga gctgcgcgcc cgtgacgccg cgcaggtcca gcagctgctg
     2701 gtacagccgg ggcagcgggt cacggccggc gagctgctgg tacgtctgga caactcggaa
     2761 tggcgtgcgc ggcgcttcct gctggaggcg gcgagcacgc cgatggaaag cccgaatgcc
     2821 gccagcctgg cagccgaacg ggcgctgctg caggagtcgc tggcgggtgc cgaagcgcgc
     2881 gtacggcagg tccagcggct gctcgatgcc ggcgcggcaa cccgtggcga gttgctggcg
     2941 gcgaccgatc tgcgtgatgt acggctgcgc gaactgtatc agctggagca gcggcgccag
     3001 ccggatgccg gacccgaaca gcgccagcgc gatctggagc tggcctggct ggacagccgt
     3061 ttgcaggggc tggaactgcg cgccgagaac gatggccgcg tcggcgaaat cctcgtcgcg
     3121 cctggcgaga acgtcgggcc gggcacgccc ctgttgcgcg tcgagagcga cggcgaggcg
     3181 caggtctggg tttatctcga tccgcgccac gctgccgagg ccacacccgg aaagctgctg
     3241 acgctgatct ttcccgacca tagtcaacgc caggcggtag tgattcaggc ggtggacgat
     3301 gccgcgccgg tgccggtcga actgcgccca ccgttcagtg cgccgacacg caggctgcgc
     3361 gtgattgcgc gggtgcacga tggtctgccg cctgagtggc gcattgaccg gctcggtctc
     3421 aaggcgcgct tcccgcaccg atggttgcca tttggcggct gaaacgtctc agcccgccag
     3481 ccactgcgga atgcgccgat ccaggtagta acgcgggcgg cgcggtgtgc cttcgacaaa
     3541 gccgacgtgg ccgccgcggc ggtgcagctc cagggttgtg gtcgccgaca gttcggttgg
     3601 ttccggcacg ctgtggcgaa acacgaaggg gtcgtccgcg gcctggatca gcagggttgg
     3661 tgtcgtgatc tctggcaggt agtagcggct ggaggcacgg cggtagtagt cctgggcgtc
     3721 gctgtagccg tgcagcggtg cggtgaagcg accgtcgaaa tcccagaagg tgcgcatgcc
     3781 gtgcagcggg ccgaggctct gcaaggcacc gaggtggttc agcagcccct cgcgctggaa
     3841 gcgctgctgt ttgtccctca cgtaggccac catcgccttc atgaaatgcg cgcgcctggt
     3901 gtcctgacag acgcgcggga atcgcggttt cgccacgatc ccgcattcct gctgctaggc
     3961 gaccccgact cgcggcgggg tccattcgct ttccttcacg gctgtgctca ctgccatgac
     4021 gagcttgtcg agattgctgg ccgtcacgcc ctccagtgcc gaacgccccc gcagcatcga
     4081 gcgcggctgc agcagtgcat ggtagatctg ccaagggtcc gcacccctgg tcagcttgag
     4141 gacggactgg atcagctcgt gcttgagtgg gtcgaggtgc cagtccggca cccgctggcc
     4201 gcggttgccc acgttcaacg ccagcaagtt gcccgccttg atctcgtagc tgatccacct
     4261 gcgggacttg cctgtctcgc ctgatggcga cgcatttttg cctgattgtc gttttcagaa
     4321 ggcgactgca cgaaatatca ggagtcggct gcactgccag aactggccgc ctgcaaggca
     4381 gcgtagagag cggtttttcc taccttgagg cgtgcggcgg cctcgcggac attcaagccg
     4441 ttggcgacaa gctcccgcgc tcgttgcaac ttgtcggcag tgacaaccgg cttgcgtccg
     4501 cctttgcgcc cgcgtgcggc ggcagcggtc aacccggcct tggtgcgctc gcggatcagg
     4561 tcgcgctcga actggcccag cgcaccgaac acatggaaga tgagccgtcc gcccggcgtg
     4621 gtggtgtcga tgttttcagt caacgagcgg aagccgacgc cccgtgcttc cagcttgccg
     4681 accgtctcaa tcaggtgcgg cagggagcgg ccaagccgat ccagccgcca gacgaccagc
     4741 acatcgccat cgcgcagata agccagcgca tcggccaagc cgggccggtc tgccttggcc
     4801 ccggatgccg tgtcctcgaa aacccgttcg cagcctgcat tgcgcagcgc atccgtctgc
     4861 aaggcggtgt cctgttccgc cgtcgatacc cgcgcatagc cgatgagtgc catttccgcc
     4921 catttgtccg ttataccgtc cgcctatctt attgtccgtc atcccgttgc gcaagatgtt
     4981 ttcggacagg cgtccggttt ggccgcctaa tgatcgtttg gcggacaagg cgactggcat
     5041 cagccgaaca gctcgctatg ggagccaagc cgcgccagtc gcagggtgtc ggcgtcggac
     5101 ttgcggtaga tcagcagcag gtcgggcttg atgtggcatt cgcggtagcc cgcccaatcg
     5161 ccggaaagat cgtggtcgcg gtatcgcaca tccaggggct gatcggtcgc cagcgcgacc
     5221 agaaccggct tgaggtcatc attcgtgcag cggactcctg atactgttcg ttcaatagac
     5281 gactgcacaa ctgccttcaa accgcgttgt ctggtgcagt cgtcttctga aaatgacaaa
     5341 aactgcccct tgcggcaact gtccaacaaa ccaccgtttg ctgaacactt gccgggttac
     5401 gatgaaacac caacaaatgc cgctcactgc ctgccctgcc acgccttcac ggcctcggcc
     5461 tgcgcctgtg ccgcatatcc ttcatcgaga ctgccgaagg tgtccgccgc tacctcgtcc
     5521 attagggtct gcaaggccgt gtcggcacta tccgcttgcg caacaagtta ggcctgtcgg
     5581 cgggcttcca tcgctgcctc ggcggcttgc aagtcctctc ggtcttgcag ttcctccacg
     5641 atgttttcgc gccaagtcgc atcactgccc gcctcgttgc atagctcgct gagacgctgc
     5701 gcggcatcct ctgaacgagc aaaaagccgc gcacatcgca ggatgcgggc ggcttcttcc
     5761 gggttgcctc tggcttggtc gaacaagagc atttcgccca cggcggcgag ggcttcaagc
     5821 tcaagctgct tgtcgtcgcc gctcatttcg cgtgcgcctt gtgcgcctca acgtaggagc
     5881 gcaaaacagc attcatgcgc gactgataac gcttgccggt gtgcttgaag aactccaaca
     5941 cttcggcatc aatgcgcagc gtgatttgct tcttggtgtg gggcaattgc tccgctgcct
     6001 tcatccagac agcatcaggc agatagggtg catcgctata gtcgatctgc tcatccggca
     6061 tcgaggccac ggcatccagt cgcgccttct gctcggcgct caactgtggc ggcttcttga
     6121 ggtcaagagt tcgcttcacg atattgcttt ctttcgtcgg catttgcttt cctcgcagag
     6181 ataaggcgga tggtttcctc gtgtcggacg gtgtagacca catacaggac agccgagtag
     6241 gcaagcccaa tcgttgccca acgatcttcc ccgtagtcct cgcgtccgtc gtaggcttca
     6301 acccgcccgg agtcgtaaaa aacaagctcg gcatcctcga aggaaacgcc gtgctttttc
     6361 aggtttcgtg ccgctttatc ggcgtcccat tcaagttcca ttgtgttctt attgtagcgt
     6421 ctttttgtag ttacatcaag tcttatcgac tcatgccggg tgagttgtcg cgctcgatct
     6481 tctgcgcctt ggcctgctcc tgctggcgta caggctcgcg cccttccagc ttctcccact
     6541 gctggcggta cttcccaagc tcggcggctt gccggtcgcc tgcggcgctg taggcatagc
     6601 gggcggtgcg ctgcgcgtag tcgttccagt cgcgcccctc gcccttctgc cgggtggccg
     6661 gggcgcactg gcggatagcg ccctcgatgg cggcttgatc gtggccggta acgcgcatcc
     6721 gcacggcaat catggaatcc acgcgggaca agtccacctc gccgccacgc tgccgcttga
     6781 tcacgtcgcg gtaatgccgc tggtaagcgt cgatcgcgct gccgctggcc gctgcaagct
     6841 ccaaggcggg cttggctttg ctgcgttctg gctgctgcgc cttcaaggcg gcctgacgct
     6901 gatactcggc gtcgatctgg ctggacaggg ccagcgcctt gacgcactcg cggcgctcgg
     6961 ccttgagcaa gcgcacttcg ggatagctgc cgtcctcgcg ctggtgcttg ggcttgcgat
     7021 tctcgtagcc gggtgcgcgg tgcgggtgga tggctcccga tagcttcggg tcgccgtatt
     7081 cacggttcag ggcatcgctc agccggttgc ccacgtcctt gtcgtgggcc gtccccagct
     7141 tcggcacggt gatgatggcc tgatagttgc cggggcttga ttccagcaca acggcgggcc
     7201 ggtagccgtc acggataagc cgctccagct tctcccggtt catgtcgtcg atgaggatgt
     7261 gatgcttctt gtccgatagt ggcgtgtagt agaggttttc gccccggcgc tgtaggcgca
     7321 gcatctccgg cgtgcgctgc tcgatctcct gcggcgtgaa gccccgcgtg atgccgtcct
     7381 tcttgtcgag gatgaaggtt tgcttccttc cgtctgcctg catcttgatg gacgttaccc
     7441 ggtagcgctc cgcgcctacc gcttccgcgt acagctcaaa ctgctttagc tgctccgatt
     7501 tcatcgcctg cgccctctcc tgctgtatcc gctgccgctc ctgctggatg cgctcctgaa
     7561 gctcaggatt cgtgatcttg aaaccgtgct ctgctgctaa cttcgcgcac atggccttgt
     7621 attcgtcgtt cccggttacg gtgaagctgc cccacttctg cgccgatagc tgcaaggcgg
     7681 caagcgtgct gtcccggttg cgccagtcgt gaatatcgat gctttttccc ttgtccacga
     7741 aagacacacc cccgcccgcc cccgcttctt ccttccggct gtaatgcacc tgctggccca
     7801 cgatttcagg ctgataggcg cggatgtctc gcggcgtcgg cggctcgccg ctcgcgccct
     7861 cgatgcgctg cggctcgctg gcgcggtgcc gccactgctc ggcaagctcc gggcttttct
     7921 gcatccgctg ccactgctcc aggtcgggat agggccggaa ctgctgccgg tgctgctcgc
     7981 gctgcttctg gtgcttctct ttcaaggctg ctttctctgc ggcctgctcg gcggcaatca
     8041 cgctgcgcat ggcgttgagc acttcgccct tacccttcca gttgccgcgc atgagttcat
     8101 cgcggcgggc tttctgctgc tcggcaatct gcttgcgctc ctgctcctgc cgcttgtcca
     8161 gtgccagctt ggccgcgttc ttttccgcgt agtgcgcctt gcgcccggtg atgtaatcct
     8221 tccatcccgg cacgtctggc ttgatcggct ctggctcgcg ctgtgctacc tgctgacgct
     8281 gcggcggcgg ctggtaagct ccgagtcgct tttgtaactt ggataggctc gcgtcccggt
     8341 ctgcgctgct ggccttcacg ccaacatcac cgacaaagag cgtcgccccg ctgcctgttt
     8401 tctcgtagcg catccccttg gctgctaact cgcggtgcaa ctgctcccac gtctgcgcct
     8461 ttttgatgat cggtgcgccg tcctcaatgg cgatgcgttc ggcggatttc tccccggtgc
     8521 ggttttccat gtcgcgcttc ggctgggctg gctggcgcgg cttgtccttg tcgatgtgct
     8581 cccggcctaa ctcaccattc tccaacacct gataacgccc gttctgctca cgctgccagc
     8641 cttgtgcgtt ctcgattcgt gctatcgcct tgtgcgctgc ctcaatgtcg aagccgttat
     8701 tgatcttcac caccttgagc gtttcaggat gcacgcggtt gatggcaagg tgcaggtgca
     8761 agttgtccgt gtcggcgtgc aaaccataga tggcttgatg gtctttaaca cctagctcat
     8821 ccatgaaaat gcttaccgct tcttcgacct gctccgggct gggctgctcg ccttctcgcc
     8881 aactcaggac atagtgattg atcgtgtcct tgcttcgcac tgcctcttgt gacaaggcaa
     8941 tcatttctgc cgtctggctc tgtggttcat cggtgatgaa tccacgcgcc ccggcatgga
     9001 tgcacttctc ctgcgagttc tcacgctccg gctcgcggat gtagtcggtt aggcgagaaa
     9061 cgcgaaccgc cttgcttgct gccttctgcg ggttcttaac cttcttgacg atcacggctc
     9121 agtttcccga tgtaggcttt cagggccaca agtgccccgg ctgtgtcctt gttgtaaatg
     9181 cctccgcttt cgttgtggat gtgcttgagc aatccaccga tgcgccgcag ctccttgagc
     9241 atcacggcgt cggcgttggc aatgatcggc ctgccgaagt agcggcggcg gacaagctcg
     9301 gacatgctca acccggcaag gtcggcatcc tctttcaagc gggccttctc cgctgcggtc
     9361 agccgtacat tgataacggc gtccagcggt tccggcccct gcgtttcaaa tggcatcgtg
     9421 tctccttctc gccggggcgg ggggcggggt gtgtcttgga cagtaagaag cgagagcgcc
     9481 gcactgtccg gggtcaaggg gatacccctt gcaggataag ccagaccgtg agaagcgaag
     9541 cgccgaatgg gcaggcgtcc gttggaacca cgtggcgaag ccatgtgtgt tacaacggtc
     9601 atcctgtatt gctcatccgc tctactatcg tatcagcagt ttaggtgcac gggacgcact
     9661 ttgcaacaag cacaaatggc gctatgctgt caactccgca acaagtaagc aaaggagtta
     9721 gcacgatgaa gtgcacgaca gaacagctag aggctatcgc tgcaaagctg cgagagatgc
     9781 cgccagtcga gaaaaagaag caagagcaca gcaagcaaga tgccgtgcgc atactctcga
     9841 aggaaatcgc cttgttgcaa aagcgtggat acacgcttga ccagatttcc gagacgctgc
     9901 gcggtgaagg tctgagcatc gcaactccaa cactcaagag ctacttgcag agagcaaagc
     9961 cagcgaaaaa agctccggtg caagcaccgg gagacacacc ccgcccccgc cccgccgtca
    10021 agaagcctgc ggatacatca aaggcgacat tcaccccgaa acctgacagc gacgacattt
    10081 aaggagtaag caacatggcg aaaagcattt acctgatcgg tggcagcaaa ggcggcgttg
    10141 gcaagtcgct tgtcacgatg gcaacggttg attacctgca agagcgcggc gaaagcgtct
    10201 tgctgattga gtctgacacc tctaacccgg acgtatggaa agcctataaa gaaagcacgg
    10261 aaacggagct tatcaatctg gatgaggcgg acggatggat tcagctagtg aacttgtgcg
    10321 atagcaagcc ggatagcgtc gtggtaatca acacggcagc acggaataac aagggcgtga
    10381 gcgcctacgg tgaaacactg aatagcacgc ttgaagaact caagcggaag ctggtcacgc
    10441 tgtgggtgat taaccgccaa cgggatagcc tcgaactgct caaggaatac atggacgcaa
    10501 ttccgaatgc ggatgttcat gtggtacgca atggacactt cggggaagaa aataagttcg
    10561 agctttacaa cggctccaag ctgcgcacgg cggtagagga acgcggcggg aaatcggtga
    10621 cattcccgga catggccgac cgtgtgagcg atgacattta cagcaagcgc atgagcattg
    10681 cggtagcact caaggaattg cccattggca accgtgcgga gcttacgcgg tggcgcaacg
    10741 aggccaaaaa ggtattggag gccgtagtcc atgagtgacc tagacgacag ctttgcaaag
    10801 ctgctcggca ggcaacctag tgacgcggag cggcaaagtc tttaccgggt tcgggatgca
    10861 ctcggcctga aaaacaatga tgcgctgtgg ctggtgctca tggccttgca acactaccaa
    10921 ggccagtatg agaagttccc gcaagcgata gcacaagcag ccaaagatac cttggtcaat
    10981 ttcaaggtaa cggcggatgc aaccgtgaaa gcatcagcgg aagcagccaa ggcggatttg
    11041 gcgcaagcgg tagcagcagc agcgcaagag gtcgcgcaca acacatcagc aaagcagatg
    11101 tggcagtggg cggcgggctg catcgccgtg gccttcctgt gcgtcggcct gttcggctgg
    11161 tacatgcaca gcagcggcaa ggattcgggc tatcaggccg gatacggcgc gggatacacc
    11221 gaagccaagg acgagaaagc ggcggcggca tgggccaaca cgccagaggg gcgcttggcc
    11281 taccgcttcg ctcaaacggg aagcctcgcc agcttggcga agtgcgatag gccggggtgg
    11341 tacgtcgaaa aaggcgtgtg ctacgtcaag cccgcatcgg atggcaccta cggatggagg
    11401 ttgccatgag aatcaagatc aaaggagaaa tcacggcaga acgcctagcg gaagcactgc
    11461 acgcagcagc agaaaaatac gaagctgtga ggccggggca caaggtctat ggggccaatc
    11521 tttacctcac ggcattcgat gcggatggtc tgcctttcga tctggtagac catcgcggcg
    11581 aaccgctttc gatcaccatc gaggccaagt ctggcgaact ggtaaaacca gcactcacag
    11641 cagagggtga agcacgccga cagaaagcca aagaggaagc acgaaggcaa gctgaagaag
    11701 cggaagctga agcacagcgc agacacaggc aaaccttaga cgaatacgaa caggagcggc
    11761 aaaaacgacg gaaaaaggaa gccgaagcaa gaaagcaatt tgaggacgcg aacgcaatca
    11821 ctgcagaact cttgaaaacc atgccggaac gcttcatcga cgaactgaac aaaaccgtgc
    11881 aaggcgtttg gggcgacctc aagccaaccg aaacgcaagg caagaagaag ggccagccga
    11941 aagcactacc agtcttttcc gtccatgcgg acggcctgtt gctctccgtc gagacatgaa
    12001 agaacccacg ccgggtgctc aatccgcttt gcacacttca gcacggaaaa atagccccat
    12061 tctggatgca cgaagcgtgg ttagaagcca tgtgtgggat gcgaataaag attcatccgt
    12121 acaaataaag tctcattctt tgaaatagag tttcatccta aaacagaggg caaagcctcc
    12181 tgcgggacgg tggccacttt cggccctgcc ggtcgccgtc cgttcgtgcg gcgctgcaag
    12241 tatcgcagca cacccagcgt catgcgggcg tcggcaaggg cgcggtgtgc gccgtcttct
    12301 gccacgccgc agtcggtcgc agcctcgatc agcttcaacc atcgccagcg gtcgcggctc
    12361 cggtcgtact ctccatgcca ctcggcatac atcagcatcg cgcaagcggt cgtcaacact
    12421 ggcgcggtga gtccgtgtat ctgataggtc tgccgcagca agcgcgcatc aaaagcgacg
    12481 ttgtaggcaa cgacggttcg gccagcaacg gcggcggcgt actgctcggc cacctcgggc
    12541 cagctcggcg cactggccac catggcgtcg gtgattttgt gaatcgctgt cgcctcgacc
    12601 gggattggcc gggtcgggcg taccagcgtg tcgaggatcg gtgcgccggt cacgtcgagt
    12661 atggttatct cgcaaatctc ggcgtcatca ccgaggccgg tggtttcggt gtcgagcaca
    12721 atgcagcctg cggcgatcag gtcttttgcc tgcgctgcga cgtgctggcg acggacttgg
    12781 gcacgcccag gcatccagcg ccacggcacg cactcggctg ggttgtacac atcataagcc
    12841 ccctgacctt gccagacact gccagcgggc ttggtgttta gtcccggcat gaggcggagg
    12901 cgttccttga ggtgcttacg gcatagaagc cccttggcct ctgcttcggt cggggtgagg
    12961 tgttttcggg ttttgggcat acgcccccct tgttggtgtc tcagtcccgg cggtagtggg
    13021 cgacgattca gacgctcgaa agtatgagac tttattttca cgattcaggc cgcgcccaat
    13081 gccacgcgat cctttcagaa tgacacttta cccgcctgcc aagcctgagt ctttcaaaac
    13141 agtcctgaaa attggcgtag cttaggatgg gactttattt gcatcccaca gcttcgctgt
    13201 ctgcggcctc tctcgcccac catgcaggcc gggcggctgc ggatgacagc gcccccacgg
    13261 cccacaatgc aagctcctga tcgcccaggt tcgcagcctg cacgatcacc gccccaagct
    13321 gccgcaactc atcggacagc gcctgaaatt ctgcggcgct tggcatcact cgcccccctt
    13381 ccctttcggt gccttcgtgg ccttctcggc ggcctcggcc ttgtcctgct gccgttgcag
    13441 cgcctcaagc tgcccggcaa gtcgtgcggc ctgctcgcgg gcctctgctg ccaccttgcg
    13501 agcctcgtca cgctcggcct gcgtctgccg ggtttcctgc gctgctgcgg cgcgggcggt
    13561 gtcgtgggcc tgtgcagcct tggcggcctg ctgctcgatc tgctcggcgc gggcctctgc
    13621 gcggctcaca cggtcggcgc acgcctccag cttggcggcc agcacggcgg cctgttgttc
    13681 ggcggcggtg cggccctgct gtgcctcggc cagtgcggcg cgtaggcgct caagctcggc
    13741 ggcctgctcg ctcacgcgct cggcctgcgc ctcgatcttg tgccgggcgg ttgccacctc
    13801 cagccgggca gactctgccg cctgctgctc gcgctcgatg cgctgctgcg cctcggccaa
    13861 gtcggtggcc tgctgggcgg ctttgcctgc cagcgtgtcg cgctcagtgg tcagcacggc
    13921 cacctgctcg gccagctcgt cgcgttcgcc ttccagcacc tcgccagcgg cggccagttc
    13981 ggcggcctcc gcctgcgcct gcaccagacg gccctcgatc tcgccgcgtg cccgcgatgc
    14041 ggcccgctcg atctcggcgg caatggcagc ggtcagcgcc tgcggcagtt ccggcgcagc
    14101 ggctgcggcc accgggcggg cctcgcgcca cgcggtcaag tgcttgtgaa tagtgttcgg
    14161 gctgccggtg tcgcccagct tctcccgcac cgcccggatg gtcggctgct gaccctcgcc
    14221 tgccagcgca tcagcgacgg cggcgacctg ctcaaaagtg atgccctgac gtgccatgat
    14281 cgttgctcct ttcgtaccgt atcagtgtaa atcgtatcaa tacagatatg atacgcaata
    14341 cagatacgat atgcgagcgg ttttcgtaac gtaccgctgc ccggtcggct gctcgttttt
    14401 ggtgaaacac cgtgctgacg cctcgccttc ggctcgttgt cggccagccg tcgaacgaaa
    14461 agcggagctt tccgcccgcc gcccggctcc ggccagaaac gggcctacag cgcgttttga
    14521 gaaggtaaga aagggggcag gcagggccac gtcgagaaaa cgccgccacg ggccgcctgt
    14581 gaggtcgtcc gccgtccggg ttttcgagtg gagagggggt caagcgaacc gtggaataaa
    14641 tggggggtag cccgtaggag gcaccgttta tgccgcgaaa gtcgcttgat gccctcggaa
    14701 cggctcacgc tccccgagtg gggcaggggt ttaggccgta ggccgtcccc ctgctcccga
    14761 ggatcaaacg cgaccgtttg gcccccggca gggccgccgg aggcatcttg caaacacgat
    14821 caaggcgaca gccgtttgac cgcatctacg aatggcaacc tgaacaggtg catggtcagg
    14881 tcgatggcac cgccgccgcc ctgctctgcc cgcgtgtcgt accacttcgg cccggtcgcc
    14941 agtagctcaa caccaccgcc accgatggac acattcagcc gtaccgtggc cttgtccttc
    15001 accggcacaa agtcaggatc acgcttccag tacaggccca gccggtctag cgtttcctgc
    15061 accgtcattg cccgcaacga atgcagcgcg ggcggaaagg atcgacgggg gcggctcatg
    15121 acagccaccc gacaaactgg acgagggggc cgccctgcgg gcggcgggct actcgcattt
    15181 ttagaatgct gggggctact caaaggcagg cgcttcgcgc cgggcgtagg cttcgccatt
    15241 agtaatacgc agggacttgt ctcacgcatc tgaatcaccc gcagcggcct gtaatacgca
    15301 gggacttgtc tcaaccgctg gcgttggctt gcctgctcga taccagcttg cccggctcat
    15361 gcccaaggct tcccacggct tctgacggct cgcggagttg gcctcatagg tcgcacgatc
    15421 gacagcccca gcggcccgcc tgcgggcctc gtcacgcttc ctgtggcgct ctgcggccat
    15481 gtcccggctg attccccggc ttcgtgagcc ttggccttgg cgtacagcgt cataagctcg
    15541 gcgctgcggt agttccaccg tgggtcaagc tcacgggcca gcgtgcgcaa gtcctccaga
    15601 cgatcccacg ccagttgccg cccgttgagc gtgcgcaggt tgccggtttg gccgcccggc
    15661 agcagcttga actggcgacg gtcggcgcgg gccttgcggt cggcctcgat gtcccagcgg
    15721 gccaccggca gtagcgcctc ggccagatac tcgaagttgt accggatcgg ctcgccgtcc
    15781 gggccttgct caacgtggat gacgcggcaa acctcgccgc tcttgctgtt caccgtattg
    15841 accagccgca gcacgcggct tgcatccttc acttattgca acactccatc acttacatga
    15901 tactgatgac tcatccaact gaggaccagc cttgaccatc gctgaaacca gcgaccgatc
    15961 aagccccctc gccagtcgag ctccactgga taatcagggg cgcatccaaa tctaaggagg
    16021 agggtggacg gccagcctga aaaacaggca tagccagcgt gggtgggatg cgaccataaa
    16081 acctgcatcg gcgcagacca gatctgcgtg gcaacccgca agggtcatgc gccacaaggc
    16141 aatgcaccat tggtaatgca gaccctcggg tcatacgcca ttggcaacac aggcacacac
    16201 atcgatgccc ggcatcacgc taaccgaagt ggttatgctg ttcggcctct gcctcaatcg
    16261 cgcggatagc tgatgcgacc gtgatgcgac gatagccccc cgccgtctct gtcagacaga
    16321 gacggccagc gcccacccgg cgccactcca gagccctcgg gccatgccgc cagctctccc
    16381 aggcacgaaa accgacgaaa tcgtcactca caggccagcc ggacgctagg cgcagtcgca
    16441 ccacgactag cgccctgcct gcaggagccc cctgccatag cagccccccg ttcctcggaa
    16501 ccacagcacg ctcaccgcgt aaggagttta aaaccgatgc cccacgacac gcgcagtcgc
    16561 aaacatgcgc aaaacactca acaccatgat caggggatgg ggcatcaaaa caacaaaacg
    16621 atcaatcaaa ataggatttt gatatggcgc gatgtgatag agcccacccg aacgcgagaa
    16681 attttggcct cggcagccgc gacatggggt atgccgggct gaatgccctg cgcgagggga
    16741 tgcaaagcca cagttcgatc gccaccatgg cggatcgctg gtcccagttc gccgcctggg
    16801 cgcgtgaggc tgcgggcatc cgtgatatgc gccagatcgt gactgacaca ctgcgcggct
    16861 atgccgacca cctgctcacc cgattggagc aaggggagat cagccccgct accgcccaaa
    16921 atgcgctctc cgccgttaac cgcgtattgg agatcgcccg tggcgatcga ttggtacggc
    16981 tcgatcccgt gcacgaggct ggactaccga tccgtagcgg gatcgccacc actgatcggg
    17041 ccgtatcgtt gtcccagcac gaccacgccg tggctaccgt ctccgaacgc gtggccgcca
    17101 tcctatccct gcaacgcgct tttgggctca ggttcgagga ggcggcgaaa ttggacgcgg
    17161 tgagggccct agcacaggcc caacatggca tggtgcgcat cgaggtcggc accaaaggtg
    17221 gtctggcccg cgatgtcccg ataaccaacc cactggagca aaaatttctg ctagccaacg
    17281 cggccaatat ccaagagaac gcgcgcagcc tgatccccgc gcatcagacc tatcgtgaat
    17341 ttcgcgcgga ggcctatgcc gagttgcgca gcgcgggcat tcgctcgcac ggcgaacgac
    17401 acgcctacgc ccaagagcgc tacgccgccc tagtgggggc ccccgcgccg gtcgctgcgg
    17461 gggttgccca cggcgcagca caccatcggt ttttggcagt tcgactcggg ctcaccgtgg
    17521 cggcggcgcg ggcgctcgat cagcaggccc gcgagcgggt cgccgccgag ctaggccacg
    17581 gccgcctcga tgtcaccaac acctacctgg ggtaacgatc atgagcagca tggaaacgtg
    17641 gatcagagcc cgggtcgatg tctacctgcg tcacggtggc aaaaccagcc gaagagctac
    17701 tgtcagcagg ctgattgccg ttttagagga cattcgtcag catgagcagg gggtgaggct
    17761 accgccccag gtaggacggg cccatctcca ccgctattgg gcccgccaga gacacctttc
    17821 cgagcggacg cgacaggacc attggtatgc ggtgcggctg ttgtgggagt tactggacag
    17881 ggctggccag cagccccgtc ctccgttaca atcaagtttc gattttgatt agtcaaaata
    17941 ggattgtgat atggaagagc tgcaagcgaa gtggacgttt gaccaaggcg gatttgccaa
    18001 ggcgctgatc gtacccaccc cgatgggcca gggctatcac ctgcacctgg tgaagttcgg
    18061 caaacagagc gagaccattt tcctggaacg acaacgggga ggctggcggg tgttcaagag
    18121 catcgatgcc gccgccaaca ccgccaatgg gataggcttt aggcgcatcg agatcgatct
    18181 aagtagccgc tgagatggtg gaaccaccaa gagaaagaac gctccgtgga taagccctcc
    18241 tgcccacagg ggacaagccc ctgatggaca gcccaacggg atcgggctta accacctcgc
    18301 caagatcctc tctcgatgat gtgcgcgatc gcacgctggg cagtatgtga gatttccccg
    18361 ttctgcccga ccaaccacac ccacacacgg caacaaactc atgcttccaa tccgtgcggg
    18421 tacgacaaag cgccaaaggt ggtggccttc ggtaacgggt cgagttgcgg gaaaagcttg
    18481 attgaatggc cgaatggccg ctaaactgat taggactttt ggtagctgct tcccgcacgg
    18541 agccgttacc aggtgaagtc ggttccccaa ctgacaacac cttcgaagaa accgccctgc
    18601 aaggcggttt tttcgtttct ggttgccaga atacgcgccg gatagagatc agcgcaaggg
    18661 cgtcatcgtg atcaagcgcg taaattgcag atcagggtaa agatccaaca aaccagttga
    18721 tctaatttgt cgagccaaca accgccaatc aagccaatct acggattggc tttttttcat
    18781 tatttgatac caaataaata tgttttttgt attctataag aaccaaataa acatcaaatt
    18841 aggagcctca aatgatcgtt gctgtggcac ataacaaggg aggggtcggt aaaacgacga
    18901 cagtagtgca actggcggga gaactgaaac cggagatcat catagatctg gacgcacacc
    18961 agggaattgc catcatcaac ggccgacgac cagcagagct acgctgggat gtgagagcaa
    19021 acctcgacaa ggcagccctg atcaagttgt tgaaggcggt tggtgagcat ctggttctga
    19081 tcgactgtgg tgggtttgac agcgagctgg ttcgaatcgc catcgctgcg gcagatctga
    19141 tcatcgcccc gtcaaacgac gacatcacag aacagatcgg gctagtgagg ttcaaccgag
    19201 tgctttccga aatcagccaa gcaactgggg aacctatcca agcgcatgtg ctgatgactc
    19261 gcaccaatcc cagccgcaag aattttgcag cgatcagcga tgagctaacc aggctgccgc
    19321 acctcaccat gatgacctcc aagttgagcc gacgggcaga ctgggccaac caaatggagt
    19381 caggtttggg agtgacggag agagcagcta ctcgcagcag cgcagcgggt atggaggcaa
    19441 aagcattggc ggaagaagtg cggtcaaaac ttgccatgct gacaaaacaa tattaattta
    19501 atatcaaatg aacacaaaag agatgttttt atggcaaaaa aactaatcaa tctggacgac
    19561 cttggcgctg gagcccccct aaaagaggtg gtaacggcga ctgacggcag cagagggaag
    19621 atccctacca aggccaagaa catccagaac atgccactag aattttttac acgccacgca
    19681 gcgttgaggg agaagggcaa taccagcttg ctattcaccg cgtacatcat cgaggcagtc
    19741 cgcaaagcgc tggaagacga cgaacagagg taacaattac gtagcgagcc atacccgcca
    19801 gtgagcatga cctcaataca acagataaag agaaaagtgg cgtcagttta ccggaacgcc
    19861 tgttactgca cataaattct tcagcaactc ttgatagagc caagtaaagc ccacagatcc
    19921 agttagaggg acatcctcta acacactaaa gggtaacagc tatggctctt aaaccaggtc
    19981 cgaaaccaat tgctaagtca accgggaaac cggatcaacg tcgccgtgat aataaagata
    20041 cgccggggaa taccgattcg ttaaaaccca gcaaatccac aaagaagtaa gaatgcctgg
    20101 gaataaacac accatctcca ctgtgggaaa gtggggccag tggccccaca atcaaagtcg
    20161 aaatttgacc aatcattttt aacttttgac aaccacctcc aaacgagagg cgacgagaga
    20221 catctgtcgc gccaggatag gaagtcggca aacgcagcgc gaccaatgat agcggcttta
    20281 tttttaccaa atattctgac ttatgaattt aagttcttgc cttattttca taacagatgg
    20341 attgacggtt gccttgactc tattaattgt cattgactcc cctggattaa gaagctcaat
    20401 tggcttagac ctcgctgatg acattcgacc acaacccaaa aaatcatcca acaaaagaat
    20461 gtgattatca ggatcctggg tagtgaaatg agtaatgttt cgactcacaa tatctctcac
    20521 cttttccaga tacactttcg tttgattatt tggtttgttc tttgctccag gaacagttga
    20581 ccaaccacag tgggttaaaa caaccatctg tatttttgga gtgtgctgat ttgatggcat
    20641 tactcgccta aattcacttg ctggattaga cagtgtatct agcaaaagct ccaaggagtt
    20701 aattgattgc tgatctgttc tgaccggaac aatcaaggca tctgcagcat gccatgacag
    20761 atgtgtagcc ccagagaaga acggggaggt gtcaatcaag cacttggatg tctccgtctc
    20821 cccccactct cggctaatct cttttttcaa ggaaaaaagc atgttgtcaa taattgacac
    20881 ttgatttggg ccagcaatta accttgcctg cgccaaggcg ttagctattt gagttggaag
    20941 tatataaaga tcgctactag atggaatgaa atagctattt tttgatgcaa aaaaattgtt
    21001 tgtggcgctg atttttttgg caaccctagt tgcaaaacct aagccaggaa caaaataagg
    21061 cattagcaaa tcatttacac ttaatgaatt tgaagacaag aagttattat caaaaaaata
    21121 agaaagatta ccttgtgggc aggtatccaa aacgagaaga tcatctgtgt aataagaaag
    21181 attaaaagct agagaagtct ttcctatccc cccccttaaa ttgcaaatgg cgtacgtatc
    21241 aaacttaggc aaccccaaag gggcagcaac accattcgca atatcatcct gtcgatcaat
    21301 caacttggca acactagtca taacccaccc ctctcgatta gttttccaca ttgtgtgaca
    21361 aaaaggaaaa ctagtcaaag tgaaagagca actatggaaa gttagtgcac ataacgcctt
    21421 ttatgttcaa ttgccgattt cgcatggcaa aacggctact ccgtcaggat atggccgcct
    21481 gtatcgcgtt tttgggcgtt tcgacacaca agacagggca tttactgcct gaaagtttgc
    21541 aacgcttctg gggcggtttt agggccggat cctgcggggt atggtttcag cgcgttttag
    21601 cggcctatcg cgcattagtt tcggttgccc tccgagcgat ttgttccctc cccgccctgc
    21661 aaatgtccca cttctgtccc ggttttgtac cgcttctgtc ccacttttgt accggatctg
    21721 ttccggttct gtaccgctat ccgcttcgcg gtgtcccagt acccccgaac aggggtcgcc
    21781 tcagaattcg gacaataaag cacgctaacg gctggcgtgt caggttgagg ccatagacgc
    21841 cgcgccgaag gcgtcaggaa attccggaaa aggccctact ctgacgctct ttcgccgctt
    21901 cgtctgacgc ccggttgggc tatagcctag attgacatgc gcgatgcaac ccttaacttg
    21961 cttgcaccta tcgtttccat gctagcttta tcgtaacgct caagaaattg ggcttaatgc
    22021 cgaaaacaat aaaataaaac agccaaccct tgaggttctt atgcgccaga atttaccagt
    22081 gacgggtcga aacttagaac tcccaaaaga tgccaatatt ctttcgacta cctcccctca
    22141 aagccatatc acgtacgtta atcctgactt cattaaaatc agtggtttca ctgaggaaga
    22201 actattaggc cagcctcaca acatcgtaag acacccagat atgccgcctg ctgcatttga
    22261 gcatatgtgg agtacattaa aatctggccg ctcatggatg gggctagtaa aaaatcgctg
    22321 taaaaatggc gaccactatt gggtaagtgc ttatgtaacg ccaatagcta agaatggttc
    22381 gattgttgaa taccagtctg taaggaccaa gcctgaacct gagcaggttt tggctgcgga
    22441 aaaattatat gctcaattga gaagcgggaa ggccgcgagg ccgaaattgg ctgctagctt
    22501 ttccgtgaaa atactcttgc tcatatgggg tagtattata tcaagcgcaa tggctgccgg
    22561 catgcttact gatacatcaa taagcagctt attgttagcc actttaatgt caggaagctt
    22621 aagctctgtt agtgttttgg ctattctctc tcctcttgga agactggttg aaagagccag
    22681 gaatatttcc aataacccat taagtcaatc cctctacact gggcgcaccg atgagtttgg
    22741 ccaaatagag tttgctttac gaatgatgca agctgaaaca ggcgccatag taggtcgcat
    22801 aggtgatgca tcaaatcggc ttagcgaaca cacccgaggc ctactaaagg atattgagtc
    22861 aagcaatgta cttacagttg agcagcaggc agagacagat caaatagcaa cggcagtaaa
    22921 ccaaatggtg gcaagcattc aagaggttgc gagcaatgca cagcatgctg cagatgcggc
    22981 cggaagagca gacactgaga cggcatctgg ccagcgtctg gtagcccaca caagccagtc
    23041 aatcactgcc cttgaaggtg aaattaggca agccactcag gttattcatg agcttgaagg
    23101 tcaaagtaac gagatatcaa aagttcttga cgttatacga gggatcgccg agcaaacgaa
    23161 tttgttggca ctcaacgcag caattgaggc cgcgcgtgct ggtgagcagg ggcgtggttt
    23221 tgctgttgtc gccgatgagg ttcgcagtct tgctgctcgc acacagcaat cgacaacgga
    23281 tattcaaagc atgatcagcg ctctacaaga gcgagcgcaa tccgctgtta cagtcatgga
    23341 gcaaagtagt cggcaagcgc acacgagtgt agctcacgca gaggaagcag ctacagctct
    23401 tgatggaatt ggccaacgcg ttaacgaaat taccgacatg aacgcgcaaa tagcgactgc
    23461 ggtcgagcag cagggagcag taagtgaaga cataaaccgc agtattatca atatacgcga
    23521 tgctgctgat accaatgtac agaccgggca gaataatttg caaagtgcga aatctgtcgc
    23581 tcagttaact agcgctctga gcgaactggc aaaacagttt tgggaaaaac gaggataacg
    23641 cttttcagta tctcgacagg gataacttac tttaccatcg gttatccctt ttagccgcac
    23701 aaattttagc catggctttt caggaagtca gggctatcag aatggcctta gaaagcctag
    23761 tcaaagagct gtcacgagaa caccgttagc ttagcgtacg attttttccg aattctgcgg
    23821 ttcccccatg aagagctcaa aaacaacggc ccaaaggccg cgcaaaaagg atgtcgccaa
    23881 gctccacagt cagcgggctc tcctatcttt ccgctgcgct tcaagatagg agagccctcc
    23941 tgcttggcta cgttaaaaat aacgtagtta cacaagattg actcgccttg ctccggacta
    24001 tcgagactgc ttgcggcagc tccctctcac gcgctccaga gacacacccc gtccttgctg
    24061 catctgcttt agcctccgcc tgatggccag actgccgcgc cgttttttaa gagctggccg
    24121 tggttggttc cccgttacgc tctgcttgca gatgccccac ggttgcgaat cgtgggcggc
    24181 tgtggtgcgc gatcacacgc tgggcagtat gtgagatttc cccgttctgc ccgaccaacc
    24241 acacccacac acggcaacaa actcatgctt ccaatccgtg cgggtacgac aaagcgccaa
    24301 aggtggtggc cttcggtaac gggtgtaaag agggaattag cttgaaagat acggcaaagt
    24361 gccgctaaac ttactgggac ttttggtagc tgcttccctc tacggagccg ttaccaggta
    24421 caaagagcgc caactccgag taccttcgaa aaaccgcccg ccaaggcggt tttttcgttt
    24481 ctggcgtaca gagtagcgtt gatcagactg atcgatcaac gctttttagt acgcactact
    24541 gcaaaaaaat actcatatat tcaatactat cccgacagga tagttgataa tcaatcgatc
    24601 acggcaaggc ttcaacaaag tccgtcatga tatccttgat ggacttcccc tgcgcagctg
    24661 catgcatttt cagcttggtg tgcaacgcct ccggcaggtc gaaattaacc cgcttcatct
    24721 tcacggatcc ggcaatatca cccatggtca ttgcccgctt ttcactgctg ggacggccag
    24781 ctttcagcac gctcatttac tcacaccctc attaactcat ttgagtaatt ctaaaacttc
    24841 atctgccaag tcacgtattt cctgggctgc attgctgtta ggctcagcat caagcacggt
    24901 ggtacctgca gctgctgtgc tcggatacgc aacgctttgg gtcactctcg ctgccaatac
    24961 cggcagacca taaccctcca gcgcctctct gatctcagcg ccgatcttgg tgttcttgat
    25021 ggctcgactt accacaaacg cagccttcaa acggccatcg gtcatctcta tccgctgctt
    25081 caccagatcc accagatcag aggccgccca aatatcgtaa ggagagggtt ggacagggat
    25141 cagcaccaga ttgcttgcct tgatcgcgga tatcgctagg tcagcggcct gcggagcacc
    25201 atcgatcacg atcaagtctt tgtgggacac cgccttgata tcgcgctcga tggttggcct
    25261 atctatcccc accactggca ccggttgctc atcacgcact gcagaccaat ctcttgcgct
    25321 tccctgggga tcgctgtcga tcaacagcac atcgcgaccc gccacctgaa aggctcgcgc
    25381 tagatgagtg gcaatcgtgg ttttgccgct ccctcctttc tggttcaaca ccgatataac
    25441 cagcatgccc accccactca attgagttaa tgagtaaaga agtaaatcat caaatgagct
    25501 ttagacgcaa gaggttgcca ctccttgttg ttgtcttggt tgctgtcttg gcaggagttc
    25561 caagagactg gccgctatgc cacagctcaa gatttagatc agtggctaac ctcttggggc
    25621 acttatgccg aagggcatat aacgcccgca atcaaaatac aaaaacgaac aatcaatatt
    25681 tagctttgat tagctattta gtggctggat ggatgccagg catggggcta acgggcaaca
    25741 tccaactacc agtgactagg cagccgtaac ctggtatgaa acaccctcaa aatatggatt
    25801 tcctctccct ttactcggta tggaatgagg aacgggtaag gttgcaccac aagctcgcgc
    25861 gtacctggga cacgtcccga ccttcccatc gagggctgtt cgaccagcag attaaccaag
    25921 cgatacacct cgtgcgcaaa ctcctgggca accctggggt tttcttttgc caagtaatcg
    25981 tgagcatctt cgaggttcag cgcagcctta cgcagccatt taacctgcat tgatacccca
    26041 ccgattgaac ttcgccatca tctctttttc agatacgaag tcacccgcat ccgcttcacg
    26101 caaggcggct tctacctccg tgatctgcca ggcctcacgc gccaaataat ccttaatagc
    26161 ctggttagcc aaccaggatt tagtcctgcc agtggactgg gctaactgcc ccaactgttg
    26221 ctctacctcg tccggcaaac ggacagacat cacgctcata cgcccctccc gacactacaa
    26281 tgtttacaat atgctacata ctacaccctg agcagcagca tggcgacatg cccgagatgg
    26341 caatctgggt aaccgcagca ccggcgtgaa gagggctcct gaatgtccgg cgcagacagt
    26401 gaaaccactc ctgcagcttc cctcgatgtc cggccaagac aacagacaac aaaaaggggc
    26461 gccggattta ccgtaacgcc cccttatgcg caattattgc taaatcaatc atccgttagg
    26521 gaaggtgcgg aatgacggcc tgatcaatat tcaagcgtcg aggccgacga atagctggtg
    26581 aataaccctg aaagaacttg tagaatgagg caatcaagta tcacatagcc attatccggt
    26641 tttccttccc atgtccccca tgccacgcgt cgctgtcctt ggtgcgtctt cttcccctgt
    26701 tgtcggtatc gaatacgagc ggcaccccga gtggtccgcg ctcgcggcgc tgccggcgta
    26761 tgacatcgtt ctgctcgatc tgccggcggt gcgcgccggc gaagcgttgc gcagcctgcg
    26821 tatggacaag cgctaccgct tcagcctgat ctactgctgc caggagcagg acgcgtcttg
    26881 caaggcgctg agcgacggcg cgccgccggc tgatctgagc gccctggtgc cgctctggcg
    26941 gctctggcag gagcgcttcg cgctgttcaa ccgtggggtg gcgccggagc gtttcgagtc
    27001 gcgcgtgctc gcctggctgt ggttgcaccc gcacggcgcc atccatgcgg tgcgcgatgc
    27061 cggcgtggcg cagcactatc actatccgct gctggaggcg ctggaggacg acgagtcgcc
    27121 gaacgccttc gcctggctac agctgatgac ccagcagggc tggctggaag agggcgagct
    27181 ggtcgatcgg gtgcgcctgt gcgtcggttg tggctccggc cggttgaact acgtggatgt
    27241 ctgccccgag tgccagacgc tggaaatcgc ccgtcagccg tcgctgcact gcttcacctg
    27301 cggccacgtc ggcgcccagg agcacttcct caaggatggc ctgctgctct gcccgaactg
    27361 tttctcgcgc ctgcgtcaca tcggcagcga ttacgaccgg ccgctggaga actatcgctg
    27421 ccgcagctgc caggcgttct tcgtcgatgc cgaagtcgag gcgcgctgcc tggactgtgg
    27481 ccaggcccat gcgccggaca agctgcgcgt gcgcgaggtg cgtcacttcc gcctcgccga
    27541 ggccgggcga ttgcgctgtc ggcagggcta ctcggccagt gtcgccgaga ccgatcagtt
    27601 cggtgcgctc aacctgctca accagaagtc cttccacgag ctgctcaact ggcagctgca
    27661 gctggtgcgg cgctacaagc agccggcgtt ctccctgctg gggctgcggt tcgtcaacct
    27721 ggcggcgacc atcagcgcac tcggcgagct gcgcggccat gcgctggtgg acagcctggt
    27781 ggagcggctg caggaagccg tgcgcgacac cgatcgctgc agccgggtca gtgaagagat
    27841 tctctggatc atgatgccgc acaccgatgc ggccggcctg gcagtggtgc gtaaacgcct
    27901 gcaggaaggt gccgagcggc tggccagcga gcagatcggc cagctgcagc tgcgtcagat
    27961 cggcttcacc gcaccggccg acctgctcga acaggaagat gccgcgttgc tgctggcgcg
    28021 cctgaacggg gagctgggct gagatggagg gtttctggct gcagtggctg gggattctcg
    28081 gcgaaatcga caagcccgac ggcctgggct atctgctggt gatgctgttt ccggcgtttc
    28141 tgttgctgga ggtgccgctc agcctggtga tcctgctcgg cgtgctgcgc tggttcgtgc
    28201 gcaaaccctt cgagctgccg gaaggcaaca gttaccagcc gcgcgtgtcc tgcgtgatca
    28261 cctgctatag cgaaggtcgg gatgtgcaga ccacgctgct cagcctgtgc gagcagacct
    28321 atcgcggcga gatcgagatg attccggtgg tcgacggcgc gacggccaat cacgcgacga
    28381 tgcaggccgt gcgggatttt cgcctcgatg cgcagttgta tccgcggcgc tttctgcggc
    28441 cgatcgccaa gtggcagcgt ggcggacggg tgtcctcact gaacgctggg ctggaataca
    28501 gcaccggtga gatcgtcatg gcgctggatg gcgatacctc gttcgacaac gacatggtgg
    28561 tcaacgtggt gcgccatttc caggacccgg acgtgccggc ggtggcgggc agcctgcggg
    28621 tgcgcaacgc tcgcgcctcg ctgaccacgg cgatgcaggc gctggaatac ctgctgtcga
    28681 tccagctggc caagatcggg ctcagcgagt ggaacgtggt gaataacgta tccggcgcgt
    28741 tcggcgcctt tcgtcgcagc tttctgcaga aaatcggtgg ctgggatacc cataccgccg
    28801 aggatctgga tatcaccctg cgcatcaaga actacttcgg ccgccggccg ctgcgcattc
    28861 cgttcgagcc ccgcgccatc ggccataccg acgcgccggt gacgttccgc cagttcctca
    28921 tgcagcgcct gcgctgggat ggcgatctgt tcttcctcta tgtgcgcaag catcgccaca
    28981 gtttcacgcc gcgcctgctc ggctggccga actttctggt
//
