LOCUS       NZ_AP024780            23753 bp    DNA     circular CON 10-JAN-2024
DEFINITION  Klebsiella pneumoniae strain TUM12135 plasmid ColRNAI, complete
            sequence.
ACCESSION   NZ_AP024780
VERSION     NZ_AP024780.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMD00323038
            Assembly: GCF_019703145.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1
  AUTHORS   Sugita,K., Aoki,K., Komori,K., Ishii,Y., Iwata,S. and Tateda,K.
  TITLE     Complete genome of KPC-2-producing Klebsiella pneumoniae
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 23753)
  AUTHORS   Aoki,K. and Ishii,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-JUN-2021) Contact:Kotaro Aoki Toho University,
            Department of Microbiology and Infectious Diseases Toho University
            School of Medicine; 5-21-16, Omori-nishi, Ota-ku, Tokyo 143-8540,
            Japan
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.8-beta
            Genome Coverage                   :: 112x
            Sequencing Technology             :: Illumina MiSeq, ONT MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/10/2024 03:30:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,382
            CDSs (total)                      :: 5,259
            Genes (coding)                    :: 5,135
            CDSs (with protein)               :: 5,135
            Genes (RNA)                       :: 123
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 12
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 55 of 124
            Pseudo Genes (incomplete)         :: 73 of 124
            Pseudo Genes (internal stop)      :: 13 of 124
            Pseudo Genes (multiple problems)  :: 15 of 124
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AP024780.1.
            Annotated by DFAST https://dfast.ddbj.nig.ac.jp/
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..23753
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="TUM12135"
                     /isolation_source="bile"
                     /host="Homo sapiens"
                     /db_xref="taxon:573"
                     /plasmid="ColRNAI"
                     /geo_loc_name="Japan"
                     /collection_date="2012-01-05"
     gene            1..1965
                     /locus_tag="K6J93_RS26645"
                     /old_locus_tag="TUM12135_51250"
     CDS             1..1965
                     /locus_tag="K6J93_RS26645"
                     /old_locus_tag="TUM12135_51250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004178196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="WP_004178196.1"
                     /translation="MFNTDSLAWKWHIPELARQIYPWVSWLYQEYYGLAGAFLVIGLFF
                     GLAELWAGRMRFVGLSHKERREYADRYKRDNKRPAPFSVLASLDSPGRMVRARRHVWNY
                     AYWLTGAAGLALLGGLVVAVFIESWGETVLRPDLYANADYYLLQPANLFGIAWCAGGLA
                     VGIVLARLLAFLLLDGHFAAADEAVNAKLNQESRRSSQRTGEMTDVRHLHFGEPVPVNA
                     LADFSSEQARQEQAVFLGKDEQGKPVLVPRDTWRKTNIQILGLPGSGKSVMATNALIRC
                     VRDFGDAVVYFDPKGDAWAPHVFRAHCPDFTLLDLRPGKPAQLNLFRDLDQYALKNLLI
                     AGLNLGETGDVADHYRISEQKAAKLIAEQFPQGANIQQVLAAAYALPEALKKDVKGLIT
                     RLENVADLSVLQTDSGIDVAGIINGGGCLYVIGSMDDEAVIRVQKMLFARCAQIIIARD
                     EFREWPHVSVMLDEIKYLLSKYVLNALGTLRSRDCNLLLAHQSLGDFGQCGQDLPAEFV
                     KTTVLDNTPIRWFYRAASLESAQWAAGQTGEIRVDVERRRASREAGNVEHISGDSFIQK
                     EARPLFDVNTLQHLPDGFAVMTGLGVARMAFSSPLRVERREIPLQRFPVLAKTDPLAEF
                     RPPADGGGPKADDDFAGIY"
                     /name="TraM recognition domain-containing protein"
     gene            1965..2696
                     /locus_tag="K6J93_RS26650"
                     /old_locus_tag="TUM12135_51260"
     CDS             1965..2696
                     /locus_tag="K6J93_RS26650"
                     /old_locus_tag="TUM12135_51260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family replication-relaxation protein"
                     /protein_id="WP_004152551.1"
                     /translation="MALELYNVSHAKRQARNAEKTRLTLRWLREELCSTAELVARRLGI
                     AAVQPVYRFLDSLVAKGLLVRTKYPVDGRQVSVWGLTPHGVAFSFDEDEPLADVIPFQP
                     SRVSAAHLPHRLAVQSLRLDMEARGATGWRILHRLSLKGMKVPDALAELDGKTVAFEVE
                     RTVKSRRRYQEVVSGYLFNRKANGIDEIWYICPDRATQVRVQRAILSVDEIVNPQTGEA
                     RKTAELDRERLFACFKFMTTE"
                     /name="MobC family replication-relaxation protein"
     gene            2703..3233
                     /locus_tag="K6J93_RS26655"
                     /old_locus_tag="TUM12135_51270"
     CDS             2703..3233
                     /locus_tag="K6J93_RS26655"
                     /old_locus_tag="TUM12135_51270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008321413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004153058.1"
                     /translation="MALYMVFIEDAEDRNGERCIMPTSEHLEDMVVLAWQTGAYVFCFV
                     DRAQHLAMMKSIGMYDERLNSDEKATYFFTGKNPQWERNKPTGMKLCDYLYRKVERFAI
                     ENGVQVVDAGKCSPEQINAMIDVVSERHGESAVNEKLKAELMREYNSRYFNVPVPELPE
                     DKPARRWWPFGKK"
                     /name="hypothetical protein"
     gene            complement(3261..3440)
                     /locus_tag="K6J93_RS26660"
                     /old_locus_tag="TUM12135_51280"
     CDS             complement(3261..3440)
                     /locus_tag="K6J93_RS26660"
                     /old_locus_tag="TUM12135_51280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_000165971.1"
                     /translation="MTKQEKTALNMAKFIKEQSLLLLDKLNELDMDTPADMCERLHEDA
                     ETLWQVMRDKLGEE"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            3509..3886
                     /locus_tag="K6J93_RS26665"
                     /old_locus_tag="TUM12135_51290"
     CDS             3509..3886
                     /locus_tag="K6J93_RS26665"
                     /old_locus_tag="TUM12135_51290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000312627.1"
                     /translation="MAWVTVRQATELTGKARSSLYRDMAKGRVSYRTEADGGRVVDTSE
                     LIRVYGELRQDETHERDELRLSGETEKMASDALIAEIKALREEVAGLRQEMQSMRLLEH
                     KPETAETPAGTPRRWWPWGKR"
                     /name="hypothetical protein"
     gene            complement(3948..4247)
                     /locus_tag="K6J93_RS26670"
                     /old_locus_tag="TUM12135_51300"
     CDS             complement(3948..4247)
                     /locus_tag="K6J93_RS26670"
                     /old_locus_tag="TUM12135_51300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146176.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_001146176.1"
                     /translation="MPYDVEWKQGAIEDVTTLFDYIAENSSLWDAQNVTDRVLAAADKL
                     ADFPRLYEVDSRYGEDVRRISLMGQHVLYDVDDQTRKVRVLAVVGQRQNPHIVL"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(4237..4500)
                     /locus_tag="K6J93_RS26675"
                     /old_locus_tag="TUM12135_51310"
     CDS             complement(4237..4500)
                     /locus_tag="K6J93_RS26675"
                     /old_locus_tag="TUM12135_51310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000072676.1"
                     /translation="MSNTTHYENANFLRELAESLPRILPEGGPDKAALLQRLANEELAQ
                     AEYEDQVRAKVTAARADTRPGMTTEQLRQRLHGRYQELRDAV"
                     /name="hypothetical protein"
     gene            complement(4806..>5096)
                     /locus_tag="K6J93_RS26680"
                     /old_locus_tag="TUM12135_51320"
                     /pseudo=""
     CDS             complement(4806..>5096)
                     /locus_tag="K6J93_RS26680"
                     /old_locus_tag="TUM12135_51320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247941.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Exc2 family lipoprotein"
                     /name="Exc2 family lipoprotein"
     gene            complement(<5164..>5739)
                     /locus_tag="K6J93_RS26685"
                     /old_locus_tag="TUM12135_51330"
                     /pseudo=""
     CDS             complement(<5164..>5739)
                     /locus_tag="K6J93_RS26685"
                     /old_locus_tag="TUM12135_51330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611787.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /name="Tn3 family transposase"
     gene            6099..7418
                     /locus_tag="K6J93_RS26690"
                     /old_locus_tag="TUM12135_51340"
     CDS             6099..7418
                     /locus_tag="K6J93_RS26690"
                     /old_locus_tag="TUM12135_51340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004152397.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element ISKpn6 family transposase"
                     /protein_id="WP_004152397.1"
                     /translation="MAASYLPYRPDQSYLLPPSLGEWLPEGHLAYFISETVDTLDLSAF
                     HARYAGGGPGNQPFHPAMMVKVLIYGYASGVFSSRKLARKLYEDVALRVLAAGNFPAHR
                     TLSDFRALHLTELENLFVQVVQLARECGLVKLGTIAVDGTKVKANASRHKAMSYKRMKP
                     AEDELHCEIKALLDRAKATDDQERNEPELDIPAEISRREKRLEAIQAAKARLEARQREA
                     DQARGRSEDDGRRPRHPDGSDKGGGSYKREFGVPDDRDQESFTDPDSRIMKHAGGGSEQ
                     SYNGYTAVDAEHQIIVAAELTNCAADSQALLGMLAAVQANTGEMPAQTLADAGFRSEAV
                     LAKVADHHGDVIVALGREGREDAKVNAKTHPHTAAIAAKLKTEQGDAAYRRRKSIVEAP
                     NGWIKAVMGLRQFSMRGLDKVQAEWKLVCMALNLRRMAYL"
                     /name="IS1182-like element ISKpn6 family transposase"
     gene            complement(7668..8549)
                     /locus_tag="K6J93_RS26695"
                     /old_locus_tag="TUM12135_51350"
     CDS             complement(7668..8549)
                     /locus_tag="K6J93_RS26695"
                     /old_locus_tag="TUM12135_51350"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015256839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbapenem-hydrolyzing class A beta-lactamase
                     KPC-2"
                     /protein_id="WP_004199234.1"
                     /translation="MSLYRRLVLLSCLSWPLAGFSATALTNLVAEPFAKLEQDFGGSIG
                     VYAMDTGSGATVSYRAEERFPLCSSFKGFLAAAVLARSQQQAGLLDTPIRYGKNALVPW
                     SPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGPAGLTAFMRSIGDTTFRLDR
                     WELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQQFVDWLKGNTTGNHRIRA
                     AVPADWAVGDKTGTCGVYGTANDYAVVWPTGRAPIVLAVYTRAPNKDDKHSEAVIAAAA
                     RLALEGLGVNGQ"
                     /name="carbapenem-hydrolyzing class A beta-lactamase KPC-2"
     gene            complement(8601..8840)
                     /locus_tag="K6J93_RS27140"
     CDS             complement(8601..8840)
                     /locus_tag="K6J93_RS27140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004152395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004152395.1"
                     /translation="MIQVGQYYFGDSGVKWVSFQLVLTPAYPRCYLRAPIVGAWPGLPE
                     AVRNVDAEVRRGGRPMNADLIRFSSSVIIPAVAA"
                     /name="hypothetical protein"
     gene            complement(8837..9616)
                     /gene="istB"
                     /locus_tag="K6J93_RS26700"
                     /old_locus_tag="TUM12135_51360"
     CDS             complement(8837..9616)
                     /gene="istB"
                     /locus_tag="K6J93_RS26700"
                     /old_locus_tag="TUM12135_51360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004152394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element ISKpn7 family helper ATPase
                     IstB"
                     /protein_id="WP_004152394.1"
                     /translation="MNLQHERIDALCQQLKLERVATHYPVLAQQAVREDFSFTDFLEHL
                     LRHEAGCRQQRSRELLTRMACFPGIKTLEDYDFSFNPGVPKALVQELGSLAFVERAENV
                     VLIGPSGIGKTHLAIALGYKAAQAGVKTRFITAADLMLQLSTAQRQGRLKEYFNRAILG
                     PRLLVIDEIGYLPFGREEANLFFQVVAKRYEKGAMILTSNLPFSQWADAFAGDTTLTAA
                     MLDRLLHHAHILTLSGESYRLKDKRKAGVVRKNSKPE"
                     /name="istB"
     gene            complement(9613..10638)
                     /gene="istA"
                     /locus_tag="K6J93_RS26705"
                     /old_locus_tag="TUM12135_51370"
     CDS             complement(9613..10638)
                     /gene="istA"
                     /locus_tag="K6J93_RS26705"
                     /old_locus_tag="TUM12135_51370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032490293.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="WP_004199214.1"
                     /translation="MLTQEQTVEIRVLARQGHSIRHIARTLGVSRNTVRRYLRDPSVAR
                     YQPREPRPTKLGPFESYLRQRVEQAHPIWLPATVLNREIRAQGYGGGLSLLRAFLATLK
                     PARREAGPAVRFETEPGRQLQADFVVLRRARSPMSAFVATLGYSRMTFVTFVPDESFES
                     VRDSLLLAFDYLGGVPREVLFDNMKTVVLERDAYGDGKHRFHPGLLQLADDLGFRIRLC
                     RPYRAQTKGKVERFNRYFRESFYNPLLTRMKGTGLLLDCAAANRRVRDWLADEANVRVH
                     ATLNERPIDRWRQEREHLQPLPSRVRRDEAPLLDNSLRPVPLESLQHPLSVYDAIGEAC
                     R"
                     /name="istA"
     gene            complement(10745..13774)
                     /gene="tnpA"
                     /locus_tag="K6J93_RS26710"
                     /old_locus_tag="TUM12135_51380"
     CDS             complement(10745..13774)
                     /gene="tnpA"
                     /locus_tag="K6J93_RS26710"
                     /old_locus_tag="TUM12135_51380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004152392.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element Tn4401 family transposase"
                     /protein_id="WP_004152392.1"
                     /translation="MSKKNKLLSVLSDAEQEALYGLPEFDDAQQLEYLAVTETELALAN
                     SRPSLHAKVYCLLQIGYFKAKHAFFSFDWDEVEDDCAFVLSRYFHGEVFEPKAITKHER
                     YTQREQIAKLFGYWPWSAAFLPQLEQQAARTVRRDVTPGFVAAELIVWLNEHKIIRPGY
                     TTLQELVSETLSAERRRLGNLLEQALDESAKAALSQLLVRDDTLSQLAALKQDAKNFGW
                     RQMVREREKRATLEPLHAIAKTLLPKLDVSQQNLLYYASLANFYTVHDLRNLKADQTQL
                     YLLCYAWVRYRQLSDNLVDAMAYHMKQLEDESSAGAKQSFADEQVRRQQETPRVGRLLS
                     LYVDDSVADPTPFGEVRQRAYKIMPRDTLQTTAQRMSVKPASKLALQWQAVDGLADRMR
                     RHLRPLYVALDLSGSNPDSPWLAALAWAKGVFAKQQRLSQRPLDEWPAATLPKRLRPYL
                     LTFDADGKPTGLHADRYEFWLYRQIRKRLQSGELYLDDSLQHRHFSDELVEMDRKIDVL
                     AKMEIPFLQQPVHAQLDALTAELRTQWLAFNRELKQGKLTHLEYNKDTQKLTWRKPKSE
                     NEKAREKAFYEKLPFCDVADVFRFVNDECKFLSAFTPMQPRYAKKVADADSLMAVIIAQ
                     AMNHGNHVMARTSDIPYHVLDSGYQQYLRQATLHAANDCISNAIATLPIFPYYSFDLET
                     LYGAVDGQKFSVERPTVKARYSRKYFGRGKGVVAYTLLCNHIPLNGYLIGAHDYEAHHV
                     FDIWYRNTSDIMPTAITGDMHSVNKANFAILHWFGRRFEPRFTDLNAQLKELYCADDPA
                     QYQACLIRPVGKIDCDLIHREKPNIDRIVATLGLKEMTQGTLIRKLCTYTTTNPTRRAI
                     FEFDKLIRSIYTLRYLRDPQLERNVHRSQNRLESYHQLRSAIAQVGGKKELTGRTDIEI
                     EISNQCARLIANTIIFYNSAILSRLVTKYEAAGNSKALALITKISPAAWRHILLNGHYT
                     FQSSGKTIDLDAIVAGLELE"
                     /name="tnpA"
     gene            13884..15599
                     /gene="tnpR"
                     /locus_tag="K6J93_RS26715"
                     /old_locus_tag="TUM12135_51390"
     CDS             13884..15599
                     /gene="tnpR"
                     /locus_tag="K6J93_RS26715"
                     /old_locus_tag="TUM12135_51390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004152391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element Tn4401 family resolvase TnpR"
                     /protein_id="WP_004152391.1"
                     /translation="MKTGQTTASSSTPVGFPDADSLAALRGWYAGLSSRAAVEHYLAAR
                     KAAGQSARGMLGHIRRQLIVFANSRHRPDLADVFQHAPEERQGRAGAVERAIRLLPTLP
                     APKPQISDSIDQWLSPRTVRALQAYGIHTLSALTVRIPRRRGWWKAIEGLGMTGARQVE
                     AFFAAHPQLTERARALIPIIQPSGIVPWEQLRLPNEVDGSQGNFRAPRNACTLNATNDY
                     EAVQAWLALHETVATQRAYRKEAARLILWAIVERGRALSSLTTDDAIAYRAFVRHPTPR
                     ERWVGPPRPRDSVEWRPFSGGLSARSAAYALTVLSALFRWLIEQRYVLANPFAGVKVRG
                     HALRPALDTARGFTEGEWLLLRAIADGLEWSYGWSEPAAQRLRFMLDFGYATGLRASEL
                     VGAVLGNVRLDEHGDHWLHLVGKGGKPGKVALPPLAYTALDQYLAQRQLPVSRERWNPK
                     TPLVGSLGEDGNAGITGPHLWCVLRRFFTQAAEAIEADHPVAAEKLRRATPHWMRHSHA
                     SHALARGAQLTAVRDNLRHASIATTSMYLHGDELERARQMRQAFGARHVKRGVD"
                     /name="tnpR"
     gene            complement(<15658..18048)
                     /locus_tag="K6J93_RS26720"
                     /old_locus_tag="TUM12135_51400"
                     /pseudo=""
     CDS             complement(<15658..18048)
                     /locus_tag="K6J93_RS26720"
                     /old_locus_tag="TUM12135_51400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611787.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element Tn3 family transposase"
                     /name="Tn3-like element Tn3 family transposase"
     gene            18210..18767
                     /locus_tag="K6J93_RS26725"
                     /old_locus_tag="TUM12135_51420"
     CDS             18210..18767
                     /locus_tag="K6J93_RS26725"
                     /old_locus_tag="TUM12135_51420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221001.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001217881.1"
                     /translation="MRIFGYARVSTSQQSLDIQIRALKDAGVKANRIFTDKASGSSTDR
                     EGLDLLRMKVEEGDVILVKKLDRLGRDTADMIQLIKEFDAQGVAVRFIDDGISTDGDMG
                     QMVVTILSAVAQAERRRILERTNEGRQEAKLKGIKFGRRRTVDRNVVLTLHQKGTGATE
                     IAHQLSIARSTVYKILEDERAS"
                     /name="recombinase family protein"
     gene            19001..19555
                     /gene="aac(6')-Ib"
                     /locus_tag="K6J93_RS26730"
                     /old_locus_tag="TUM12135_51430"
     ARG             19002..19552
                     /name="aac(6')-Ib"
                     /gene="aac(6')-Ib"
                     /gene_name="AAC(6')-Ib family aminoglycoside
                     6'-N-acetyltransferase"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            19625..>19840
                     /locus_tag="K6J93_RS26735"
                     /old_locus_tag="TUM12135_51440"
                     /pseudo=""
     CDS             19625..>19840
                     /locus_tag="K6J93_RS26735"
                     /old_locus_tag="TUM12135_51440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001424636.1"
                     /GO_function="GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing protein"
                     /name="nucleotidyltransferase domain-containing protein"
     gene            19906..20610
                     /locus_tag="K6J93_RS26740"
                     /old_locus_tag="TUM12135_51450"
     CDS             19906..20610
                     /locus_tag="K6J93_RS26740"
                     /old_locus_tag="TUM12135_51450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_001067855.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            <20665..20835
                     /locus_tag="K6J93_RS26745"
                     /old_locus_tag="TUM12135_51460"
                     /pseudo=""
     CDS             <20665..20835
                     /locus_tag="K6J93_RS26745"
                     /old_locus_tag="TUM12135_51460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489893.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /name="serine hydrolase"
     gene            20951..21772
                     /locus_tag="K6J93_RS26750"
                     /old_locus_tag="TUM12135_51470"
     CDS             20951..21772
                     /locus_tag="K6J93_RS26750"
                     /old_locus_tag="TUM12135_51470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004199321.1"
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]; GO:0043022 - ribosome binding
                     [Evidence IEA]; GO:0003723 - RNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin E3/pyocin S6 family cytotoxin"
                     /protein_id="WP_004199321.1"
                     /translation="MSFRSTERQTPTPAQVKQRLEEEKRRQQAWDAAHPEEGLKREYDK
                     AKAELDAEDKNIATLNSRIASTEKAIPGARAAVQEADKKVKEAEANKDDFVTYNPPHEY
                     GSGWQDQVRYLDKDIQNQNEKLKAAQTSLNEMNESLSRDKAALSGAMESRKQKEKKAKD
                     AENKLNEEKKKPRKGTKDYGHDYFPDPKTEDIKGLGELKEGKPKTPKQGGGGKRARWYG
                     DKKRKIYEWDSQHGELEGYRASDGEHLGAFDPKTGKQVKGPDPKRNIKKYL"
                     /name="colicin E3/pyocin S6 family cytotoxin"
     gene            21782..22039
                     /locus_tag="K6J93_RS26755"
                     /old_locus_tag="TUM12135_51480"
     CDS             21782..22039
                     /locus_tag="K6J93_RS26755"
                     /old_locus_tag="TUM12135_51480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cloacin immunity family protein"
                     /protein_id="WP_004152553.1"
                     /translation="MGLKLHIHWFDKKTEEFKGGEYSKDFGDDGSVIESLGMPLKDNIN
                     NGWFDVEKSWVSILQPHFKNVIDISKFDYFVSFVYRDGNW"
                     /name="cloacin immunity family protein"
     gene            22124..22273
                     /locus_tag="K6J93_RS26760"
     CDS             22124..22273
                     /locus_tag="K6J93_RS26760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891188.1"
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="WP_004152552.1"
                     /translation="MKKVKVVFLFILIFSGFLLVACQANYIRDVQGGTVAPSSSSELTG
                     IAVQ"
                     /name="colicin release lysis protein"
     ARG             complement(7672..8549)
                     /name="blaKPC-2"
                     /gene="blaKPC-2"
                     /gene_name="carbapenem-hydrolyzing class A beta-lactamase
                     KPC-2"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             19638..19894
                     /name="aadA15"
                     /gene="aadA15"
                     /gene_name="ANT(3'')"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="97.14"
                     /coverage="32.32"
     ARG             18951..19555
                     /name="AAC(6')-Ib10"
                     /gene="AAC(6')-Ib10"
                     /gene_name="AAC(6')"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="98.97"
                     /coverage="99.01"
     Typing          complement(22377..22955)
                     /name="ColRNAI_rep_cluster_1857"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="95.361"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          1966..2693
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="1.3599999999999998e-150"
ORIGIN
        1 atgtttaata cggattcgct tgcctggaag tggcacattc cggagctggc ccggcagatt
       61 tatccgtggg tcagctggct gtaccaggag tattacggtc tggccggggc tttcctagtt
      121 atcggcctgt ttttcggtct ggctgaactt tgggccggac ggatgcgttt tgtggggctg
      181 agtcataagg agcgacggga gtatgccgat cgctataagc gcgataataa acggccagcg
      241 ccattttcgg tgctggcctc gctggattcg cccgggcgga tggtcagggc acgtcgacat
      301 gtctggaact acgcgtactg gctgaccggc gcggccggtc tggcccttct gggggggctg
      361 gttgtcgccg tgtttatcga gagctgggga gaaaccgtcc tgcgtccgga cctctacgca
      421 aacgcagatt attacctgct gcagccggct aacctgttcg ggattgcctg gtgcgcgggc
      481 gggctggctg tcgggattgt gttggcgcgg ctgctggcgt tcctgctgct tgacggtcat
      541 tttgcggctg ctgacgaggc ggtgaacgcg aaactgaatc aggagagccg gcgcagcagc
      601 cagcggacag gagagatgac cgacgtgcgc cacctgcatt tcggggagcc ggtaccggtt
      661 aatgcgctgg ccgatttttc ctcggagcag gcccggcagg agcaggcggt gtttctgggt
      721 aaggatgagc agggcaagcc ggtgctggtt ccgcgtgata cctggcgcaa gaccaacatt
      781 cagatcctcg gcctgcccgg gagcggcaag agcgtgatgg ccaccaacgc gctcattcgc
      841 tgcgtacgcg atttcgggga cgcggtggtg tacttcgacc ccaaagggga cgcatgggcg
      901 ccgcacgtct tccgggcgca ctgtccggac ttcaccctgc tggatctgcg gccggggaaa
      961 ccggcgcagc tgaatctgtt ccgcgatctc gaccagtacg cgctgaaaaa cctgctgatt
     1021 gccgggctta acctgggcga gaccggcgac gtggcggacc actaccgcat cagcgagcag
     1081 aaagcggcga agctgattgc ggagcagttt ccgcaggggg caaacattca gcaggtgctg
     1141 gcggcggcgt acgcgctgcc ggaggccctg aaaaaggacg tgaaggggtt gatcactagg
     1201 ctggaaaacg tcgctgacct gagcgtcctg cagacggaca gtggcatcga tgtggcgggg
     1261 attatcaacg gcggcggctg cctgtacgtt atcggctcga tggacgacga ggcggtgatc
     1321 cgtgtgcaaa aaatgctgtt tgcccgctgc gcgcaaatca tcattgcgcg ggacgagttc
     1381 cgggagtggc cacacgtcag cgtgatgctc gatgaaatta aatatctgct gtcgaagtat
     1441 gtactgaacg cactggggac gctgcgcagc cgggactgca atctgttgct cgcgcaccag
     1501 tcgctgggcg atttcgggca gtgcgggcag gatctgcccg ctgaatttgt gaaaaccacg
     1561 gtactggata acacgccgat ccgctggttt taccgggcgg ccagcctgga gtccgcgcag
     1621 tgggcggcgg ggcagaccgg ggaaatcagg gtggacgtgg agcgccgccg tgccagccgg
     1681 gaggcgggga acgtggagca tatcagcggg gacagcttca tccagaagga ggcgcggccg
     1741 ctgtttgacg tgaacaccct gcaacacctg ccggacgggt tcgcggtcat gaccgggctg
     1801 ggtgtggccc ggatggcgtt cagcagtccg ctgcgggttg agcgccggga aatcccgttg
     1861 cagcgtttcc cggtgctggc gaaaaccgat cccctggcgg agttccggcc cccggccgac
     1921 ggcggcgggc cgaaagcgga tgatgatttt gcggggattt actgatggcg ctggagctgt
     1981 acaacgtcag ccacgcgaaa cgacaggcgc ggaacgcgga gaaaacccgg ctgaccctgc
     2041 gctggttgcg ggaagagctg tgttccacgg cggagctggt tgcgcggcgg ctggggattg
     2101 cggcggtgca gccggtctac cgcttcctcg acagcctggt ggcgaaaggg ctgctggtcc
     2161 ggaccaaata tccggtggac ggccgtcagg tcagcgtgtg ggggctgacg ccgcatggcg
     2221 tggcgttctc gttcgacgag gacgaaccgc tggcggatgt tattccgttt cagccgtcaa
     2281 gggtgtcggc agcacatctg ccgcaccggc tggccgtgca atccctgcgc cttgatatgg
     2341 aagccagagg ggccaccggc tggcgcattc tgcaccgtct gagtcttaaa ggcatgaaag
     2401 tgccggacgc cctggcggag ctggacggta aaacggtggc gtttgaggtg gagcgcaccg
     2461 tcaagagccg tcgccggtat caggaagtgg tgtccgggta tctgttcaac cgcaaagcta
     2521 acggcatcga tgaaatctgg tacatctgcc cggaccgggc gacgcaggtc agggtgcagc
     2581 gggcaatcct gtcggtggat gaaatcgtga acccacagac cggcgaggcc cgcaaaacgg
     2641 cagagctgga tcgtgaacgg ttgtttgcgt gctttaaatt tatgacaacg gagtgaggga
     2701 ttatggcgct gtacatggta tttattgaag acgcggagga ccggaacggc gagcgctgca
     2761 tcatgccgac cagcgagcat ctggaagata tggtggtgct cgcctggcag accggggcgt
     2821 atgttttctg ttttgtcgac cgggcccagc atctggcgat gatgaaatcc atcgggatgt
     2881 atgacgagcg gctcaacagc gacgaaaaag ccacgtactt tttcactggt aaaaatccgc
     2941 aatgggaacg gaacaaaccc acaggaatga agctgtgtga ttacctctat cgcaaggtgg
     3001 agcggttcgc catcgagaac ggtgtgcagg tggttgatgc cgggaagtgc tcaccggagc
     3061 agattaacgc gatgattgac gtggtgagtg agcggcacgg ggaaagcgcg gtgaacgaga
     3121 agctgaaagc ggagctgatg cgggaatata acagccgcta ttttaacgtg ccggtacctg
     3181 aactgccgga ggacaaacct gcccgccggt ggtggccgtt cggcaaaaaa taaatgccag
     3241 caccggccat gccggtgctg ttattcctcc ccgagcttat cccgcatcac ctgccagagt
     3301 gtttccgcat cctcgtgtag ccgctcgcac atgtcggccg gggtatccat atccagctca
     3361 ttcagtttat cgagcaatag cagcgactgc tccttaataa atttagccat attgagggct
     3421 gttttttcct gttttgtcat gattctttcc ttccgggcat ggtgtgcgcc tgtcaggtat
     3481 actgtctcaa aaatagcggg gtgagacaat ggcgtgggtg acggtgagac aggcgacgga
     3541 actgacgggt aaagcccgaa gttccctgta tcgggatatg gcgaaaggcc gcgtatcata
     3601 ccgtacggaa gctgatggcg gccgggtggt ggataccagc gagcttatcc gggtgtacgg
     3661 tgagttaaga caggatgaga ctcacgagcg ggacgagttg agactgtcgg gtgagactga
     3721 aaaaatggcc tccgacgcgt tgatcgcgga gataaaagca ctcagggagg aggtggccgg
     3781 gctacggcag gaaatgcagt ccatgagact gctggaacac aaaccggaga cagcagagac
     3841 cccggccgga acaccgcgcc ggtggtggcc gtggggaaaa cgctgacgcg ctgtgcttgt
     3901 ccaaccggcg acggccacgc aatgaattgc gtccccgtca ccggttatta gagaacaata
     3961 tggggattct ggcgctggcc gaccacggcc agaacccgga cttttctggt ctggtcatca
     4021 acatcataga ggacatgctg tcccatcaga ctgatccggc gaacgtcctc gccatagcgt
     4081 gagtccactt catagagtcg cgggaagtcg gccagtttgt ccgccgcagc gagaacccgg
     4141 tcggtaacgt tctgcgcatc ccacagggat gaattttccg cgatatagtc aaacagcgtc
     4201 gttacatcct cgatggctcc ctgcttccat tccacgtcat acggcatcgc gcagttcctg
     4261 ataacggcca tgcaggcgct ggcggagttg ttccgtggtc atacccggac gcgtgtcagc
     4321 acgggcggcg gtcactttgg cgcgaacctg atcttcatac tctgcctggg ccagttcttc
     4381 gttagccagt cgctgcaaca gcgcagcttt gtccgggcca ccttccggca gtatgcgggg
     4441 caggctttca gccagttccc gaagaaagtt ggcgttttcg tagtgtgtag tgttgctcat
     4501 tgcggagcct cccgggttaa tgcggcaata tgaaggaagt ttagcagggg gcggtctgaa
     4561 agaatatggt cgtgtcagtc aggctgatga agcagaaagt cggtaaaaaa gggcttacgg
     4621 catccatttt acgtcaaaac atatgccatg cagttgcgtg cataggcatg cattaggata
     4681 aaatttatcg ggcgcgtttc cggcagtttt ccgggggggt tgttgcctgt tttatcccgt
     4741 agccgccgga aacgccctga gcccgtctga gcggtgcgcg taatgacgcg ttatggtaaa
     4801 tccacttact gtctgccttc atagccatcg agataaacag ctgaaatggt gtcagccagt
     4861 agccttgatt ttttcggtgt gaggtctttg ctgcggtaat cggtacccgc aaattgtgtt
     4921 gtgccttgga gtgagtttaa aaattcctga ctgtgaaact gctgaatgcg ttgctgcaca
     4981 tcactccgtg attttccggt cgctttatcc tttgcgccca tatcccagaa ctgccggaaa
     5041 aaaggcacca tcattcgtgt tgtgtcagct ttctgggtgg aaaaattggg atcaaaaggg
     5101 gtctgacgct cagtggaacg aaaactcacg ttaagcaacg ttttctgcct ctgacgcctc
     5161 ttttaatggt ctcagatgac ctttggtcac cagttctgcc agcgtgaagg aataatggcc
     5221 gagcatattg atatgtccgt ggcaaagcgg ggagaggcgt gcgatatctt catcattcag
     5281 tgtttcaccc tgcgcccgga gatgatccag agctgcctgc atataaatag tgttccataa
     5341 cacgacggcg ttagtgacca gccccagagc tcccaactga tcttcctgac cgtcggtata
     5401 tcgttttctt atctcacctt tttgaccgtg acagatggct ctggcaactg catgacggct
     5461 ttctccccga ttaagctggg tcagaatgcg ccggcggtaa tcttcatcat caatataatt
     5521 aagcagatac agcgttttgt tgatgcgccc cacttcaatg attgcctgag tcagtccgga
     5581 gggacgttca cttttcagca atgaacggac cagcactgag gcctgtactt tgcccagctt
     5641 cagggagcct gcggtccgga tcatttcgtc ccactgaagg actatttttc ggggatctga
     5701 ttgccctctg gcaatatcat tcagcacgcc atagtcggca tcatgggggg gtaagcggga
     5761 accccagaaa attccgccat tccgcattgt ggaatttttt gggggggtgg tccgcggcat
     5821 gacgacccgc caaaggctac cgcatctatc tgaggcgctg tggcgcgacg ctgaaacccc
     5881 ggggaattcc gctactccag ttccaggtcc gcaatagttc gtccaggtcg ggtggcgtac
     5941 gccggaaacg ccgatttttc cgcaaccgtt tctgcgttgt cggcaaggtg gtctcagaga
     6001 gcgctcaaga agcggttttt ctcgtatgtt tagctacggt ggcctaggag cctgcgcggc
     6061 agaagccaaa tcggcggaag atcgaggacg atacggggat ggctgccagt taccttcctt
     6121 accgacccga ccaatcctat ctgctgcccc cttctctggg agagtggcta cctgaagggc
     6181 atcttgccta cttcatcagc gagactgtcg atacgctgga cttgagcgca ttccacgccc
     6241 ggtatgccgg cggtggtccg ggcaatcagc cgtttcatcc ggcgatgatg gtcaaagtgc
     6301 tgatctatgg ttacgcgagc ggcgtcttct cttcgcgcaa actagccagg aagctgtacg
     6361 aggatgtcgc gttgcgtgtg ctggccgctg gaaacttccc ggcccaccgc acgctgagtg
     6421 acttccgtgc cctacacctg accgagcttg agaatttgtt cgttcaggtg gtgcaactgg
     6481 cgcgcgaatg tgggctggtg aagcttggca cgatcgcggt cgacggcacc aaggtaaaag
     6541 ccaacgccag ccgccacaag gcgatgagct ataagcgcat gaagccggcc gaggacgaat
     6601 tgcattgcga gatcaaggcg ctgcttgatc gcgccaaggc taccgacgac caggagcgta
     6661 acgagccgga gctggacatt cctgccgaga tttctcgccg cgagaagcgc ctggaggcga
     6721 tccaggcggc aaaggcgcgc ctggaagcgc gccagcgtga agcggaccag gcccgggggc
     6781 gcagcgaaga cgatggccgc cggcctcgcc atccggatgg ctcggacaag ggcggtggct
     6841 cgtacaaacg cgagtttggt gtgccggatg accgtgatca ggaaagcttc accgatccgg
     6901 acagccggat catgaaacac gccggtggtg gctccgagca gagctacaac gggtacacag
     6961 cggtcgatgc cgagcaccag atcatcgtgg cggcggagtt gaccaactgc gccgcggaca
     7021 gtcaggcgct gctgggcatg ctggcagcag ttcaggccaa caccggagaa atgccggccc
     7081 agacgctggc ggatgcggga ttccgtagtg aggctgttct ggcaaaggtc gccgatcacc
     7141 acggcgatgt catcgttgcc ctcggccgcg agggacgtga agatgccaag gtcaatgcca
     7201 agacccatcc gcatacggcg gcgattgcgg cgaaattgaa aacggagcaa ggcgatgcag
     7261 cttaccgccg gcgcaagtcg atcgtggagg ctccgaatgg ttggatcaag gcggtgatgg
     7321 gattgcgtca gttcagcatg aggggcctgg acaaggtgca agccgagtgg aagctcgtct
     7381 gcatggcgct aaatctgagg cgaatggcgt atctgtgagg gcgaaggtta aatggggcgg
     7441 ctcaaatgca ccccagtcgt cataacacgc cgcgcgccgc aagattggta tccttggcgc
     7501 cgacgccttg ccaattgcag agagcgccgc cgccatcgtc agtgctctac agaaaaccgg
     7561 tcacacggct ctgccgcgca gactcctagc ctaaatgtga cagtggttgg taatccatgc
     7621 cgcccgcaag ggcggcggtg gtgggccaat agatgatttt cagagcctta ctgcccgttg
     7681 acgcccaatc cctcgagcgc gagtctagcc gcagcggcga tgacggcctc gctgtgcttg
     7741 tcatccttgt taggcgcccg ggtgtagacg gccaacacaa taggtgcgcg cccagtgggc
     7801 cagacgacgg catagtcatt tgccgtgcca tacactccgc aggttccggt tttgtctccg
     7861 actgcccagt ctgccggcac cgccgcgcgg atgcggtggt tgccggtcgt gtttcccttt
     7921 agccaatcaa caaactgctg ccgctgcggc gcagccagtg cagagcccag tgtcagtttt
     7981 tgtaagcttt ccgtcacggc gcgcggcgat gaggtatcgc gcgcatcgcc tgggatggcg
     8041 gagttcagct ccagctccca gcggtccaga cggaacgtgg tatcgccgat agagcgcatg
     8101 aaggccgtca gcccggccgg gccgcccaac tccttcagca acaaattggc ggcggcgtta
     8161 tcactgtatt gcacggcggc cgcggacagc tccgccaccg tcatgcctgt tgtcagatat
     8221 ttttccgaga tgggtgacca cggaaccagc gcatttttgc cgtaacggat gggtgtgtcc
     8281 agcaagccgg cctgctgctg gctgcgagcc agcacagcgg cagcaagaaa gcccttgaat
     8341 gagctgcaca gtgggaagcg ctcctcagcg cggtaactta cagttgcgcc tgagccggta
     8401 tccatcgcgt acacaccgat ggagccgcca aagtcctgtt cgagtttagc gaatggttcc
     8461 gcgacgaggt tggtcagcgc ggtggcagaa aagccagcca gcggccatga gagacaagac
     8521 agcagaacta gacggcgata cagtgacatc aacgatattc cttgtttgaa ggtggagcta
     8581 ggtgtagcgg ccggatgtaa tcaggccgct acagctggga ttatcaccga gcttgaaaaa
     8641 cgaatcaggt cggcgttcat gggtcggcca cctcgcctga cctcggcatc cacgttacgg
     8701 acggcctcag gaagtcctgg ccaagccccg actattgggg cgcgaagata gcaccgaggg
     8761 tacgccggtg tcaacaccaa ctgaaaactg acccacttta cccctgaatc accaaagtaa
     8821 tactgaccca cctggatcat tcgggtttgg aatttttcct gaccactccc gccttcctct
     8881 tgtccttcaa gcggtagctt tcgccgctca gggtcaggat atgggcatgg tgcagcagcc
     8941 gatccagcat cgcggctgtc agggtggtat cgccggcaaa cgcgtcggcc cactggctga
     9001 acggcaggtt cgaggtcagg atcatcgccc ctttctcata gcgcttcgcc accacctgaa
     9061 agaacaggtt cgcttcctcg cgtccgaaag gcaggtagcc gatctcatcg atcaccagca
     9121 gccgtggacc gaggatggcg cggttgaagt attccttcag ccgcccttgt cgctgcgccg
     9181 tgctcagttg cagcatcagg tcggctgccg tgatgaagcg tgtcttgacc ccggcttgcg
     9241 cggccttgta acccaaggcg atggcgaggt gggtcttgcc gatgccagag ggtccgatca
     9301 gcaccacgtt ctcggcccgt tcgacaaacg ccagactgcc cagctcctgc accagtgcct
     9361 tgggcacgcc ggggttgaag ctgaagtcat agtcctccag ggtcttgatg cccgggaagc
     9421 aagccatccg cgtcagcagt tcgcggctgc gctgctggcg acaccccgct tcatgccgca
     9481 acaggtgttc caggaagtcg gtgaagctga agtcctcgcg caccgcctgc tgcgccagga
     9541 cggggtaatg cgttgccacc cgttcgagtt tgagttgctg gcacagggcg tcgatccgct
     9601 catgctggag gttcatcggc aggcctcccc aattgcgtca tagacagaca gtgggtgctg
     9661 gagagattcc agtggtaccg ggcggagact gttatccagc aggggggcct cgtcgcgccg
     9721 cacacgggat ggcaagggtt gcaggtgttc ccgctcctgc cgccaacggt cgatggggcg
     9781 ctcgttcagg gtggcgtgga cccgcacatt cgcctcgtct gccaaccagt cacggacgcg
     9841 tcggttggca gcagcacaat cgagcagcag ccccgtgccc ttcatccggg tcagcaacgg
     9901 gttgtagaag ctctcgcgga agtagcgatt gaagcgctcg accttgcctt tggtctgggc
     9961 ccgatacggg cgacacagcc ggatccggaa ccccaggtca tcggccagtt gaagcaagcc
    10021 ggggtgaaaa cggtgcttgc cgtcaccgta ggcatcgcgt tccagcacca cggtcttcat
    10081 gttgtcgaac aacacctcgc ggggcacacc gcccagatag tcaaaagcca gcaacaggga
    10141 gtcccgcacg gactcgaagg attcgtccgg tacgaaggtg acaaacgtca tgcggctgta
    10201 tcccagcgtg gcgacgaagg ccgacatggg ggatctggcc cggcgcaaga ccacgaaatc
    10261 agcctgcaac tgccgtccgg gctcggtctc gaaacggacg gccggacctg cttcgcggcg
    10321 ggcgggcttg agcgtggcga ggaaggcgcg caataacgag agaccgccgc catacccttg
    10381 agcgcggatt tcccgattca ggacggtggc aggcagccag atggggtggg cctgctcgac
    10441 ccgttgccgc agataagatt caaatggccc cagtttggtg gggcgtggtt cacggggctg
    10501 gtatcgcgct accgacggat cgcggaggta gcggcgcacg gtattgcgcg agacccccaa
    10561 cgtgcgggcg atgtgccgga tggagtggcc ctgtcgggca agaactctga tttccacggt
    10621 ttgctcctgg gtcaacatcg acggcctcga aaaggccgcc aaactagccc aggtggatca
    10681 gttttacttc gctggggtgg gtcagtttta cactgctgct aacacggaac cgctgaaaat
    10741 tccgtcactc cagttccagg cctgcgacga tcgcatcgag atcgatcgtc ttgccgctgc
    10801 tttgaaaggt gtagtgcccg ttgagcagga tgtgccgcca tgccgcaggc gaaatttttg
    10861 tgatgagtgc cagcgccttg ctgttgccgg ccgcctcgta cttggtcacc agccgcgaca
    10921 agattgccga gttgtagaaa atgatcgtgt tggcgatcag ccgtgcgcac tggttgctga
    10981 tctcgatttc aatgtcggtg cgaccggtca gttccttctt accgccgacc tgggcaatgg
    11041 ccgagcgtag ctgatggtag gactcgaggc gattttgcga gcggtgcacg ttgcgttcca
    11101 gttgcggatc gcgcaggtag cgaagcgtgt agatgctgcg gatgagcttg tcgaactcga
    11161 agatcgcgcg ccgcgtcggg ttcgtcgtgg tgtaggtgca cagcttgcgg atcagcgtgc
    11221 cctgcgtcat ttccttcagc ccgagtgtgg cgacgatccg gtcgatgttc ggcttctcgc
    11281 gatggatgag atcgcagtcg attttcccga ctggccgaat caggcacgcc tgatactgtg
    11341 ctggatcgtc agcgcagtag agttctttca attgcgcgtt gaggtcggtg aagcgcggct
    11401 cgaaccgccg gccaaaccaa tgcaggatgg cgaagttggc cttgttgacg ctgtgcatgt
    11461 cgccggtgat cgcggtcggc atgatgtccg acgtgttgcg ataccagatg tcgaacacgt
    11521 ggtgggcctc gtagtcgtgc gcgccgatca ggtagccgtt gagcgggatg tggttgcaca
    11581 gcagcgtgta ggcgaccacg cccttgccgc gcccgaagta cttgcgcgaa tagcgcgcct
    11641 tcacggtcgg ccgttcgacg ctgaatttct gcccgtcgac ggcaccgtac agcgtttcga
    11701 ggtcgaacga gtagtatggg aagatcggta gcgtggcgat ggcgttgctg atgcagtcgt
    11761 tggccgcgtg cagcgttgcc tggcgcaggt actgctggta gccgctatcc agcacgtggt
    11821 acgggatgtc gctggtgcgc gccatgacgt ggttgccgtg gttcatcgct tgcgcgatga
    11881 tgaccgccat caggctgtca gcgtcggcga ccttcttcgc gtagcgcggc tgcatgggcg
    11941 tgaacgccga cagaaacttg cactcgtcgt tgacgaagcg aaacacgtcg gccacgtcgc
    12001 agaacggaag cttctcgtag aatgcctttt cgcgcgcttt ctcattctcg ctcttgggct
    12061 tgcgccaggt cagtttctgc gtgtccttgt tgtattcgag gtgcgtcagc ttgccctgtt
    12121 tcagctcgcg gttgaacgcc agccactgcg tgcgcagttc ggcagtcagc gcatcgagtt
    12181 gggcatggac gggttgctgc aggaagggga tctccatttt tgcgagcaca tcgatcttcc
    12241 tgtccatctc aaccagttca tctgagaagt gccggtgttg caggctgtcg tcgaggtaga
    12301 gttcacccga ttggagacgc ttcctgatct ggcggtacag ccagaactcg tagcggtcag
    12361 cgtgcaggcc ggttggttta ccgtcggcgt cgaaggtcag caggtacggc cgcaagcgtt
    12421 tcggaagtgt cgccgcgggc cactcgtcga gtggccgttg cgacagccgc tgctgcttgg
    12481 caaaaacacc tttggcccag gccagcgcgg caagccatgg actgtctgga ttggagccgg
    12541 agaggtcgag cgcaacgtac agtggacgaa gatggcggcg catgcggtcg gccagcccgt
    12601 ccaccgcctg ccactgcaag gccagcttgc tcgccggctt cacgctcata cgctgcgccg
    12661 tggtttgcag cgtatcgcga ggcatgatct tgtaggcgcg ctgccgcacc tcgccgaagg
    12721 gcgtgggatc ggccacgcta tcatcaacgt agagtgacag caggcggcct acccgcggcg
    12781 tttcctgctg acggcgcacc tgctcgtcgg caaaggattg tttggcacca gcgctgcttt
    12841 cgtcctccaa ctgcttcatg tggtacgcca tcgcatcgac caggttgtcg gagagctgcc
    12901 ggtagcgtac ccaggcatag cacagcaggt agagttgggt ctgatcggcc ttcagattgc
    12961 gcaggtcgtg gacggtgtag aagtttgcca ggctcgcgta gtacagcagg ttctgctgcg
    13021 agacgtcgag tttaggcagc agtgtcttgg cgattgcgtg cagcggctcc agcgtggcgc
    13081 gcttttcgcg ctcgcggacc atctggcgcc agccgaaatt cttggcgtcc tgcttgagcg
    13141 ccgccagttg cgacagggtg tcatcacgga ccagaagctg gctcagcgcg gccttggcag
    13201 attcgtccaa cgcttgctcc agcagattgc ccaggcgccg gcgctcggcg gatagcgttt
    13261 cgctgaccaa ctcttgcaag gtcgtatagc cgggccggat aatcttgtgc tcattgagcc
    13321 agacgatcag ctcggcggcg acgaaccccg gcgttacgtc acgccgcacg gtccgtgcgg
    13381 cctgctgctc gagctgcggc aggaaggcgg ccgaccacgg ccagtagccg aatagtttgg
    13441 cgatctgctc gcgctgggtg tagcgttcat gcttggtgat cgccttgggt tcgaacacct
    13501 cgccgtggaa atagcggctc agcacgaaag cgcaatcgtc ctcgacttcg tcccagtcga
    13561 aactgaagaa ggcatgcttg gccttgaagt agccgatctg caagaggcaa tagaccttgg
    13621 catgaagact gggccggctg ttggcaagcg ccaactcggt ttctgtcaca gccagatatt
    13681 ccagctgctg cgcatcatcg aactccggca ggccatacaa ggcctcctgt tcggcgtcgg
    13741 ataggacgct gagtagcttg ttcttcttgc tcatggcccg ttcttgctat cttgaggttt
    13801 cgtagaaaca tggggcattt tcgattctac tgaaataatc gttattatcg cgttactcgc
    13861 ttttcgaatc gcaacctgtc catatgaaaa cgggccagac tacggcttcg agttctaccc
    13921 cagtcggctt tcccgatgcg gattcgctgg ctgccttgcg cggctggtac gcgggactca
    13981 gctctcgcgc ggccgttgaa cactacctgg cggcacgcaa ggccgccggt caatcagcgc
    14041 gagggatgct ggggcatatc cgccgccagc tcatcgtttt cgccaacagc cgccaccggc
    14101 cggatctggc cgacgtgttc cagcacgccc ccgaagagcg acaggggcgc gcgggtgccg
    14161 tcgaacgcgc gatccggctc ttgcccacgc tgccggcgcc gaagccccag atcagcgaca
    14221 gcatcgacca gtggctgtct ccgaggaccg tcagggcact gcaggcgtac ggtatccaca
    14281 ccctctcggc gctgaccgtg cgcattcccc gccggcgtgg ctggtggaaa gccatcgagg
    14341 gactcggcat gacaggcgcc cggcaggtcg aggctttctt tgccgcacat ccgcagctca
    14401 ccgagcgcgc ccgggccctg atcccgatta ttcagcccag cggcatcgtg ccgtgggagc
    14461 agttgcgtct gccgaacgaa gtcgacggct cgcagggcaa tttccgggcc ccgcgcaacg
    14521 cttgcacgct gaatgcgacc aacgactacg aggccgtgca ggcctggctg gcgctgcacg
    14581 agactgtcgc cacacagcgc gcctatcgca aggaggctgc gcggctaatc ctgtgggcca
    14641 tcgtcgaacg cggacgggcg ctatcatccc tgaccacgga cgatgcaatc gcgtaccggg
    14701 cctttgtccg gcacccgacc ccgcgcgagc gttgggtggg gccacctcga ccacgcgatt
    14761 cggtggaatg gcgccccttc tcgggcggct tgtccgcacg ctcggcagcg tatgcgctga
    14821 cggtgctctc ggcgctgttc cggtggctca tcgagcagcg ctatgtgctg gccaaccctt
    14881 tcgccggcgt caaggtacgc ggtcacgcct tgcggcccgc actggatacg gcgcgaggct
    14941 ttaccgaggg agaatggcta ctgctgcgcg ccattgcaga cggcctggaa tggtcctacg
    15001 gctggtccga gccggcagca caacgcctgc gcttcatgct cgacttcggc tatgccacgg
    15061 gcctgcgcgc tagcgaactg gtcggcgccg tcctgggtaa tgtccgcctc gacgagcacg
    15121 gtgaccactg gctgcatttg gttggcaaag gtggcaaacc aggtaaggtg gccttgccgc
    15181 cgctcgcgta tacggcgctg gaccaatact tggcacagcg tcaactgcca gtcagccggg
    15241 aacggtggaa tccgaaaacg cccctggtgg gcagtcttgg ggaagacggt aatgccggca
    15301 tcaccggccc tcacctttgg tgcgtgttgc gaagattctt tacgcaagcc gctgaggcca
    15361 ttgaggccga tcatccggtc gccgccgaaa agctgcgccg tgccacgcct cattggatgc
    15421 gtcacagtca tgccagccat gcgttggccc ggggagctca gctcaccgcg gtgcgcgaca
    15481 acctacgcca tgcgtcgatc gccacgacgt cgatgtattt gcatggcgat gagctcgagc
    15541 gcgccaggca gatgcggcag gcttttggcg ctcgtcacgt caagcgagga gtcgactgaa
    15601 ttttcatcat acggaatgac ggaattttct gggattcccg cttagaaccc catcatggtc
    15661 cattcgccag aaaaccgaag caccggcatc agccaggcgt ggagaaaact ggtatcccag
    15721 cagccagaaa aggccaaaga caagatcgct ggcacctgcc gtatcggtca taatttcggt
    15781 tggattcagc ccggtctcct gttccagaag gccttccagc acaaagatag agtccctcag
    15841 cgtccccggt ataacgatgc catgaaagcc ggaatactga tcggacacaa agttgtacca
    15901 ggtgatccct ctgttattac caaagtattt gcggttcggt ccggcattga ttgttctgac
    15961 tggcgtaaca aagcgcattc catctgcaga tgccacttct cctccacccc atatctgtgc
    16021 cagtggcagc gttgcctgaa aatcaaccag tctggcatta gcgctggtga tagtttcagc
    16081 ccgcagatag ttcgcttttg tccagttcag ccggtgtcgg gtcagtgcag gaacatttga
    16141 tctgatcagt ggttccagac cgatattgca ggcttcagcc atcagcacgg cgctgatgct
    16201 gacgggcaga tcatcaactc tggcactggc ttcactggca tggaaaaact catcagcaaa
    16261 tccggtatgg gcgttaattt cgagcagcaa ctccgttaaa tccaccggag ggagcagatc
    16321 actgatcatt ttgctcagtc gtttcagact gtccggctca tcaagactgg cgaggggaga
    16381 aattgtcaac cggggcttcg ggccagaaac atcgagttcg acagcctcat tttcgccaag
    16441 acgtgcagca acctgtctgt aacgactatc aagctgatgg cccagagatt ttattgcttc
    16501 ctgcgggtct gtcgggtgcc ccaaagaacg ataaacctta atccgatttg cctgccagtc
    16561 agcaccctgt agtaatcttg cacgaggatc tccccaccgg ttactgccgg taacgtagac
    16621 atccctccgt ctcagactat cctgcagttt actgagaaag cagagcgtgt atccccttcg
    16681 ggtgatatgt ttttccttgt taatcaccag ccgtttccat gactgactga tgatttccgt
    16741 tggtgcgtcg tcaaaaaact gccgccgtga gctgaactcc cggctgaggt agtcacaggc
    16801 attcagagtg gtaaccccgg caggtgcgga tgaaaattta acggtattca gcagatgggg
    16861 caggaaacga cgaacgcgcc cgtactgctc caccatttcg tcatgaaaat tatcgtctga
    16921 gggccgggca atttcacgga caagcgtgat gatttcagcc agcttttgcc tagggatgta
    16981 gctgaacacc tcagcacgaa tcgattcgtc cggtgtttct tctttcagca agtacgaaca
    17041 tgcgctggcg agcgccaatg cagatttatc cagatccttc agcgagcgga gccgtttttt
    17101 ctgcccaatc tttctggcgt cacggatgat aacggccagc atggcgtcca gaacgtccag
    17161 tgcatcatcc agcgccagcg tttcccatgc aaggacaaag gcaaccagaa ccgccatcct
    17221 tttctgcggt gacatcctgg caatattgaa caccgaagtc ataccagcat aacgtgcgag
    17281 atttttcagg cgcacagccg ggagtgtact caggttttca gcatgcaggc caaaatcgtt
    17341 cagagttttc cagcgttcaa ttgcttcatt aaacgccgga ccactgatgg tcacagggcc
    17401 ttttttcagt gattccagta aagacaggcg gctgcaatca gttggcccca gcagcatctc
    17461 cagctgtgaa cgctgttcgg ctgacggtat cagtgccagt ttgttccaca ggcgcaacgt
    17521 cgccttttcc cttacctctg aaatcaaccg ggtcagcgtg gtggctccgg ggagaataat
    17581 acgatgttgc ataagccacc ctgtcgccag gtcgaaaagc aggccaggac gttcgttgct
    17641 tatccagctc cgggtatata aaagacgggt aaggcgaaat gtccagggcc aggcaaattc
    17701 acgatactga tagtgctgac gtatcagcgc tgcatgctca cggcgggtat tttccctctg
    17761 accgtattct gcaagaacgg tgatatcacg aatcccgagc tgtctggcgg taaaatgccg
    17821 gacgccggaa ggaatatgat tcatgtcagt aagaaaagtg cccagaaaac gcacacaccc
    17881 gatttgcagg gcaataccaa gtcgattgtg atcaccccgg cttttcccga taaattcttt
    17941 atccgcttca tcaagatgaa aataacgcgc cagctgaagt tcatcgggtt cgccagtgaa
    18001 cctgccataa ctctcaacct gctcagtggt caaaaaatca acgggcatat cggcctccct
    18061 gcctgacggc ttttttaaca caactgcaac cgttcgaaat attataaatt atcagacata
    18121 gtaaaacggc ttcgtttgag tgtccattaa atcgtcattt tggcataata gacacatcgt
    18181 gtctgatatt cgatttaagg tacattttta tgcgaatttt tggttatgcg cgggtctcaa
    18241 ccagccagca gtccctcgat attcagatca gagcgctcaa agatgcaggg gtaaaagcta
    18301 accgcatctt taccgacaag gcatccggca gttcaacaga tcgggaaggg ctggatttgc
    18361 tgaggatgaa ggtggaggaa ggtgatgtca ttctggtgaa gaagctcgac cgtcttggcc
    18421 gcgacaccgc cgacatgatc caactgataa aagagtttga tgctcagggt gtagcggttc
    18481 ggtttattga cgacgggatc agtaccgacg gtgatatggg gcaaatggtg gtcaccatcc
    18541 tgtcggctgt ggcacaggct gaacgccgga ggatcctaga gcgcacgaat gagggccgac
    18601 aggaagcaaa gctgaaagga atcaaatttg gccgcaggcg taccgtggac aggaacgtcg
    18661 tgctgacgct tcatcagaag ggcactggtg caacggaaat tgctcatcag ctcagtattg
    18721 cccgctccac ggtttataaa attcttgaag acgaaagggc ctcgtgatac gcctattttt
    18781 ataggttaat gtcatgataa taatggtttc ttagacgtca ggtggcactt ttcggggaaa
    18841 agtgcgcgga acccctattt gtttattttt ctaaatacat tcaaatatgt atccgctcat
    18901 gagacaataa ccctgataaa tgcttcaata atattgaaaa aggaagagta tgagtattca
    18961 acatttccaa acaaagttag gcatcacaaa gtacagcatc gtgaccaaca gcaacgattc
    19021 cgtcacactg cgcctcatga ctgagcatga ccttgcgatg ctctatgagt ggctaaatcg
    19081 atctcatatc gtcgagtggt ggggcggaga agaagcacgc ccgacacttg ctgacgtaca
    19141 ggaacagtac ttgccaagcg ttttagcgca agagtccgtc actccataca ttgcaatgct
    19201 gaatggagag ccgattgggt atgcccagtc gtacgttgct cttggaagcg gggacggatg
    19261 gtgggaagaa gaaaccgatc caggagtacg cggaatagac cagttactgg cgaatgcatc
    19321 acaactgggc aaaggcttgg gaaccaagct ggttcgagct ctggttgagt tgctgttcaa
    19381 tgatcccgag gtcaccaaga tccaaacgga cccgtcgccg agcaacttgc gagcgatccg
    19441 atgctacgag aaagcggggt ttgagaggca aggtaccgta accaccccag atggtccagc
    19501 cgtgtacatg gttcaaacac gccaggcatt cgagcgaaca cgcagtgttg cctaaccctt
    19561 ccatcgaggg ggacgtccaa gggctggcgc ccttggccgc ccctcatgtc aaacgttaaa
    19621 catcatgagg gaagcggtga tcgccgaagt atcgactcaa ctatcagagg tagttggcgt
    19681 catcgagcgc catctcgaac cgacgttgct ggccgtacat ttgtacggct ccgcagtgga
    19741 tggcggcctg aagccacaca gtgatattga tttgctggtt acggtgaccg taaggcttga
    19801 tgaaacaacg cggcgagctt tgatcaacga ccttttggaa acggcactgt tgcaaatagt
    19861 cggtggtgat aaacttatca tccccttttg ctgatggagc tgcacatgaa cccattcaaa
    19921 ggccggcatt ttcagcgtga catcattctg tgggccgtac gctggtactg caaatacggc
    19981 atcagttacc gtgagctgca ggagatgctg gctgaacgcg gagtgaatgt cgatcactcc
    20041 acgatttacc gctgggttca gcgttatgcg cctgaaatgg aaaaacggct gcgctggtac
    20101 tggcgtaacc cttccgatct ttgcccgtgg cacatggatg aaacctacgt gaaggtcaat
    20161 ggccgctggg cgtatctgta ccgggccgtc gacagccggg gccgcactgt cgatttttat
    20221 ctctcctccc gtcgtaacag caaagctgca taccggtttc tgggtaaaat cctcaacaac
    20281 gtgaagaagt ggcagatccc gcgattcatc aacacggata aagcgcccgc ctatggtcgc
    20341 gcgcttgctc tgctcaaacg cgaaggccgg tgcccgtctg acgttgaaca ccgacagatt
    20401 aagtaccgga acaacgtgat tgaatgcgat catggcaaac tgaaacggat aatcggcgcc
    20461 acgctgggat ttaaatccat gaagacggct tacgccacca tcaaaggtat tgaggtgatg
    20521 cgtgcactac gcaaaggcca ggcctcagca ttttattatg gtgatcccct gggcgaaatg
    20581 cgcctggtaa gcagagtttt tgaaatgtaa ggcctttgaa taagacaaaa ggctgcctca
    20641 tcgctaactt tgcaacagtg ccctgataaa tctggagccg gtgagcgtgg gtctcgcggt
    20701 atcattgcag cactggggcc agatggtaag ccctcccgta tcgtagttat ctacacgacg
    20761 gggagtcagg caactatgga tgaacgaaat agacagatcg ctgagatagg tgcctcactg
    20821 attaagcatt ggtaactgtc agaccaagtt tactcatata tactttagat tgatttaaaa
    20881 cttcattttt aatttaaaag gatctaggtg aagatccttt ttgataatct catgaccaaa
    20941 atcccttaac gtgagttttc gttccactga gcgtcagacc cctactccgg cacaggtaaa
    21001 acagcgtctg gaggaagaaa agcgtcgcca gcaggcatgg gacgctgctc acccggaaga
    21061 ggggctgaaa agagagtatg ataaagcgaa agctgagctg gatgctgaag ataaaaatat
    21121 tgcgacctta aacagtcgca ttgcatcgac agagaaggcg atccccggtg caagggctgc
    21181 tgttcaggaa gccgataaaa aggtaaaaga ggcagaggca aataaagatg attttgtgac
    21241 ttataacccg cctcatgaat atggctccgg gtggcaggat caggttcgct atcttgataa
    21301 ggatattcag aatcagaatg agaaattaaa agctgcccag acatctttaa acgaaatgaa
    21361 tgaatcctta tccagggata aggctgcgct ttccggggcg atggagagcc ggaaacaaaa
    21421 ggagaaaaaa gcgaaggatg cagaaaataa attaaatgag gaaaagaaaa aacctcgtaa
    21481 gggaactaaa gattacggcc atgattattt tcctgatccc aagactgaag atattaaggg
    21541 gttgggagag ttgaaagagg gtaaacctaa aacccctaaa caaggtggtg gtggtaagcg
    21601 ggcccgatgg tatggtgata aaaagcgtaa aatttatgaa tgggattccc agcacggtga
    21661 gcttgaaggg taccgcgcca gtgatggcga acacctcggg gcattcgatc caaaaacggg
    21721 taagcaggtt aaagggccgg atccaaaacg aaacattaaa aaatatcttt aagaggtaaa
    21781 tatggggctt aaattacata ttcattggtt tgataagaaa accgaagagt ttaaaggtgg
    21841 tgaatactca aaagacttcg gtgatgatgg ttctgtcatt gaaagtctgg ggatgccttt
    21901 aaaggataat attaataatg gttggtttga tgttgaaaaa tcatgggttt cgatattaca
    21961 gccacacttt aaaaatgtaa tcgatattag taaatttgat tactttgtat cctttgttta
    22021 ccgggatggt aactggtaag caaaagttat caaggatgat ttgaaataca gacttccggt
    22081 gttcagggat gaataccggg gtttttaaat acagggaagg tatatgaaaa aggtaaaggt
    22141 tgtttttctt tttatattga ttttttcagg ctttcttctg gtcgcatgtc aggcaaacta
    22201 tatccgggat gttcagggtg gaacggtggc accatcgtcc tcctctgaac tgacggggat
    22261 cgcggttcag tagaaaagat caaaggatct tcttgagatc ctttttttct gcgcgtaatc
    22321 ttttgccctg taaacgaaaa aaccacctgg ggaggtggtt tgatcgaagg ttaagtcagt
    22381 tggggaactg cttaaccgtg gtaactggct ttcgcagagc acagcaacca aatctgtcct
    22441 tccagtgtag ccggactttg gcgcacactt caagagcaac cgcgtgttta gctaaacaaa
    22501 tcctctgcga actcccagtt accaatggct gctgccagtg gcgttttgcg tgcttttccg
    22561 ggttggactc aagtgaacag ttaccggata aggcgcagca gtcgggctga acggggggtt
    22621 cttgcttaca gcccagcttg gagcgaacga cctacaccga gccgagatac cagagtgtga
    22681 gctatgagaa agcgccacac ttcccgcaag ggagaaaggc ggaacaggta tccgggaaac
    22741 ggcagggttg gaacaggaga gcgcaagagg gagcgattca tcggaaacgg tgatgatctt
    22801 taagtcctgt cgggtttcgc cactcctgac tgattcatgg ttgagccacc ggctcccaca
    22861 gatgcaccga aaaagcgtct gtttatgtga actcagtcag gagggcggag cctatggaaa
    22921 aacgccacct gcgtggcctt gccgttttgc ctcacatgtt agtcccctgc ttattcacgg
    22981 aatctgtggg taactttgca tgtgtccgca gcgcccgccg cagtctcacg gccggagcgt
    23041 agcgaccgag tgagcgagga ggcgcaattt ccccggcacc tacaagacgg acaccggacg
    23101 cgctgatgtg gcatattgtc ccctgattaa gtctttatat tccctgataa taaattacca
    23161 ggataggtga atcatatcgg tttttcgctg aacattttac gttaacctat ctctgttgct
    23221 tttttctcct tacggagaaa tacaggtcat ccccgcgagg gcgtggctga cctcaggggg
    23281 atatcccctg cttacgctgg ctggacgcca ccgacgcacg gtctctcccc ctctttctgg
    23341 ctccgtccgg ctggacgccg gccacgccag aaattcaccc ggcccccgtc aggctcacgc
    23401 ctgaccaccc acaaaaatcc acggtgctgg acgcacctgg cgaagcagca aagctgctcc
    23461 tgattttgcg ggtggtcagc cgctcgctat ggcgaactct gacgggggcc ggaacaccgg
    23521 aaaagaccgc actggggtgc cgccttttcc tctcacacgc tggggcgtgc tcgttgttcc
    23581 tccggggctg cgccttttcc gcatggggcg gaaagaggct ggcctccgtg gtgaaagctg
    23641 aacgcaatca ccacggacgt gaccgccgcc gccatgcctt ggggcatgtc cgcggcttgt
    23701 gcagcggggg ctgcacatca cgccggcaaa ccatcgtctg aaggagagag aac
//
