LOCUS       NZ_AP024759            23753 bp    DNA     circular CON 10-JAN-2024
DEFINITION  Klebsiella pneumoniae strain TUM12128 plasmid ColRNAI, complete
            sequence.
ACCESSION   NZ_AP024759
VERSION     NZ_AP024759.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMD00323031
            Assembly: GCF_019703005.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1
  AUTHORS   Sugita,K., Aoki,K., Komori,K., Ishii,Y., Iwata,S. and Tateda,K.
  TITLE     Complete genome of KPC-2-producing Klebsiella pneumoniae
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 23753)
  AUTHORS   Aoki,K. and Ishii,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-JUN-2021) Contact:Kotaro Aoki Toho University,
            Department of Microbiology and Infectious Diseases Toho University
            School of Medicine; 5-21-16, Omori-nishi, Ota-ku, Tokyo 143-8540,
            Japan
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.8-beta
            Genome Coverage                   :: 144x
            Sequencing Technology             :: Illumina MiSeq, ONT MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/10/2024 03:23:40
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,465
            CDSs (total)                      :: 5,342
            Genes (coding)                    :: 5,219
            CDSs (with protein)               :: 5,219
            Genes (RNA)                       :: 123
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 12
            Pseudo Genes (total)              :: 123
            CDSs (without protein)            :: 123
            Pseudo Genes (ambiguous residues) :: 0 of 123
            Pseudo Genes (frameshifted)       :: 52 of 123
            Pseudo Genes (incomplete)         :: 75 of 123
            Pseudo Genes (internal stop)      :: 12 of 123
            Pseudo Genes (multiple problems)  :: 14 of 123
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AP024759.1.
            Annotated by DFAST https://dfast.ddbj.nig.ac.jp/
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..23753
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="TUM12128"
                     /isolation_source="stool"
                     /host="Homo sapiens"
                     /db_xref="taxon:573"
                     /plasmid="ColRNAI"
                     /geo_loc_name="Japan"
                     /collection_date="2011-11-18"
     gene            1..1965
                     /locus_tag="K6J96_RS27045"
                     /old_locus_tag="TUM12128_51960"
     CDS             1..1965
                     /locus_tag="K6J96_RS27045"
                     /old_locus_tag="TUM12128_51960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004178196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="WP_004178196.1"
                     /translation="MFNTDSLAWKWHIPELARQIYPWVSWLYQEYYGLAGAFLVIGLFF
                     GLAELWAGRMRFVGLSHKERREYADRYKRDNKRPAPFSVLASLDSPGRMVRARRHVWNY
                     AYWLTGAAGLALLGGLVVAVFIESWGETVLRPDLYANADYYLLQPANLFGIAWCAGGLA
                     VGIVLARLLAFLLLDGHFAAADEAVNAKLNQESRRSSQRTGEMTDVRHLHFGEPVPVNA
                     LADFSSEQARQEQAVFLGKDEQGKPVLVPRDTWRKTNIQILGLPGSGKSVMATNALIRC
                     VRDFGDAVVYFDPKGDAWAPHVFRAHCPDFTLLDLRPGKPAQLNLFRDLDQYALKNLLI
                     AGLNLGETGDVADHYRISEQKAAKLIAEQFPQGANIQQVLAAAYALPEALKKDVKGLIT
                     RLENVADLSVLQTDSGIDVAGIINGGGCLYVIGSMDDEAVIRVQKMLFARCAQIIIARD
                     EFREWPHVSVMLDEIKYLLSKYVLNALGTLRSRDCNLLLAHQSLGDFGQCGQDLPAEFV
                     KTTVLDNTPIRWFYRAASLESAQWAAGQTGEIRVDVERRRASREAGNVEHISGDSFIQK
                     EARPLFDVNTLQHLPDGFAVMTGLGVARMAFSSPLRVERREIPLQRFPVLAKTDPLAEF
                     RPPADGGGPKADDDFAGIY"
                     /name="TraM recognition domain-containing protein"
     gene            1965..2696
                     /locus_tag="K6J96_RS27050"
                     /old_locus_tag="TUM12128_51970"
     CDS             1965..2696
                     /locus_tag="K6J96_RS27050"
                     /old_locus_tag="TUM12128_51970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family replication-relaxation protein"
                     /protein_id="WP_004152551.1"
                     /translation="MALELYNVSHAKRQARNAEKTRLTLRWLREELCSTAELVARRLGI
                     AAVQPVYRFLDSLVAKGLLVRTKYPVDGRQVSVWGLTPHGVAFSFDEDEPLADVIPFQP
                     SRVSAAHLPHRLAVQSLRLDMEARGATGWRILHRLSLKGMKVPDALAELDGKTVAFEVE
                     RTVKSRRRYQEVVSGYLFNRKANGIDEIWYICPDRATQVRVQRAILSVDEIVNPQTGEA
                     RKTAELDRERLFACFKFMTTE"
                     /name="MobC family replication-relaxation protein"
     gene            2703..3233
                     /locus_tag="K6J96_RS27055"
                     /old_locus_tag="TUM12128_51980"
     CDS             2703..3233
                     /locus_tag="K6J96_RS27055"
                     /old_locus_tag="TUM12128_51980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008321413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004153058.1"
                     /translation="MALYMVFIEDAEDRNGERCIMPTSEHLEDMVVLAWQTGAYVFCFV
                     DRAQHLAMMKSIGMYDERLNSDEKATYFFTGKNPQWERNKPTGMKLCDYLYRKVERFAI
                     ENGVQVVDAGKCSPEQINAMIDVVSERHGESAVNEKLKAELMREYNSRYFNVPVPELPE
                     DKPARRWWPFGKK"
                     /name="hypothetical protein"
     gene            complement(3261..3440)
                     /locus_tag="K6J96_RS27060"
                     /old_locus_tag="TUM12128_51990"
     CDS             complement(3261..3440)
                     /locus_tag="K6J96_RS27060"
                     /old_locus_tag="TUM12128_51990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="WP_000165971.1"
                     /translation="MTKQEKTALNMAKFIKEQSLLLLDKLNELDMDTPADMCERLHEDA
                     ETLWQVMRDKLGEE"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            3509..3886
                     /locus_tag="K6J96_RS27065"
                     /old_locus_tag="TUM12128_52000"
     CDS             3509..3886
                     /locus_tag="K6J96_RS27065"
                     /old_locus_tag="TUM12128_52000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000312627.1"
                     /translation="MAWVTVRQATELTGKARSSLYRDMAKGRVSYRTEADGGRVVDTSE
                     LIRVYGELRQDETHERDELRLSGETEKMASDALIAEIKALREEVAGLRQEMQSMRLLEH
                     KPETAETPAGTPRRWWPWGKR"
                     /name="hypothetical protein"
     gene            complement(3948..4247)
                     /locus_tag="K6J96_RS27070"
                     /old_locus_tag="TUM12128_52010"
     CDS             complement(3948..4247)
                     /locus_tag="K6J96_RS27070"
                     /old_locus_tag="TUM12128_52010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146176.1"
                     /GO_function="GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA]; GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0030541 - plasmid partitioning [Evidence
                     IEA]; GO:0051290 - protein heterotetramerization [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="WP_001146176.1"
                     /translation="MPYDVEWKQGAIEDVTTLFDYIAENSSLWDAQNVTDRVLAAADKL
                     ADFPRLYEVDSRYGEDVRRISLMGQHVLYDVDDQTRKVRVLAVVGQRQNPHIVL"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(4237..4500)
                     /locus_tag="K6J96_RS27075"
                     /old_locus_tag="TUM12128_52020"
     CDS             complement(4237..4500)
                     /locus_tag="K6J96_RS27075"
                     /old_locus_tag="TUM12128_52020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000072676.1"
                     /translation="MSNTTHYENANFLRELAESLPRILPEGGPDKAALLQRLANEELAQ
                     AEYEDQVRAKVTAARADTRPGMTTEQLRQRLHGRYQELRDAV"
                     /name="hypothetical protein"
     gene            complement(4806..>5096)
                     /locus_tag="K6J96_RS27080"
                     /old_locus_tag="TUM12128_52030"
                     /pseudo=""
     CDS             complement(4806..>5096)
                     /locus_tag="K6J96_RS27080"
                     /old_locus_tag="TUM12128_52030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247941.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="Exc2 family lipoprotein"
                     /name="Exc2 family lipoprotein"
     gene            complement(5131..8136)
                     /locus_tag="K6J96_RS27085"
                     /old_locus_tag="TUM12128_52040"
     CDS             complement(5131..8136)
                     /locus_tag="K6J96_RS27085"
                     /old_locus_tag="TUM12128_52040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495017.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element Tn3 family transposase"
                     /protein_id="WP_001143775.1"
                     /translation="MPVDFLTTEQVESYGRFTGEPDELQLARYFHLDEADKEFIGKSRG
                     DHNRLGIALQIGCVRFLGTFLTDMNHIPSGVRHFTARQLGIRDITVLAEYGQRENTRRE
                     HAALIRQHYQYREFAWPWTFRLTRLLYTRSWISNERPGLLFDLATGWLMQHRIILPGAT
                     TLTRLISEVREKATLRLWNKLALIPSAEQRSQLEMLLGPTDCSRLSLLESLKKGPVTIS
                     GPAFNEAIERWKTLNDFGLHAENLSTLPAVRLKNLARYAGMTSVFNIARMSPQKRMAVL
                     VAFVLAWETLALDDALDVLDAMLAVIIRDARKIGQKKRLRSLKDLDKSALALASACSYL
                     LKEETPDESIRAEVFSYIPRQKLAEIITLVREIARPSDDNFHDEMVEQYGRVRRFLPHL
                     LNTVKFSSAPAGVTTLNACDYLSREFSSRRQFFDDAPTEIISQSWKRLVINKEKHITRR
                     GYTLCFLSKLQDSLRRRDVYVTGSNRWGDPRARLLQGADWQANRIKVYRSLGHPTDPQE
                     AIKSLGHQLDSRYRQVAARLGENEAVELDVSGPKPRLTISPLASLDEPDSLKRLSKMIS
                     DLLPPVDLTELLLEINAHTGFADEFFHASEASARVDDLPVSISAVLMAEACNIGLEPLI
                     RSNVPALTRHRLNWTKANYLRAETITSANARLVDFQATLPLAQIWGGGEVASADGMRFV
                     TPVRTINAGPNRKYFGNNRGITWYNFVSDQYSGFHGIVIPGTLRDSIFVLEGLLEQETG
                     LNPTEIMTDTAGASDLVFGLFWLLGYQFSPRLADAGASVFWRMDHDADYGVLNDIARGQ
                     SDPRKIVLQWDEMIRTAGSLKLGKVQASVLVRSLLKSERPSGLTQAIIEVGRINKTLYL
                     LNYIDDEDYRRRILTQLNRGESRHAVARAICHGQKGEIRKRYTDGQEDQLGALGLVTNA
                     VVLWNTIYMQAALDHLRAQGETLNDEDIARLSPLCHGHINMLGHYSFTLAELVTKGHLR
                     PLKEASEAENVA"
                     /name="Tn3-like element Tn3 family transposase"
     gene            8298..8855
                     /locus_tag="K6J96_RS27090"
                     /old_locus_tag="TUM12128_52060"
     CDS             8298..8855
                     /locus_tag="K6J96_RS27090"
                     /old_locus_tag="TUM12128_52060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221001.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001217881.1"
                     /translation="MRIFGYARVSTSQQSLDIQIRALKDAGVKANRIFTDKASGSSTDR
                     EGLDLLRMKVEEGDVILVKKLDRLGRDTADMIQLIKEFDAQGVAVRFIDDGISTDGDMG
                     QMVVTILSAVAQAERRRILERTNEGRQEAKLKGIKFGRRRTVDRNVVLTLHQKGTGATE
                     IAHQLSIARSTVYKILEDERAS"
                     /name="recombinase family protein"
     gene            9089..9643
                     /gene="aac(6')-Ib"
                     /locus_tag="K6J96_RS27095"
                     /old_locus_tag="TUM12128_52070"
     ARG             9090..9640
                     /name="aac(6')-Ib"
                     /gene="aac(6')-Ib"
                     /gene_name="AAC(6')-Ib family aminoglycoside
                     6'-N-acetyltransferase"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            9713..>9928
                     /locus_tag="K6J96_RS27100"
                     /old_locus_tag="TUM12128_52080"
                     /pseudo=""
     CDS             9713..>9928
                     /locus_tag="K6J96_RS27100"
                     /old_locus_tag="TUM12128_52080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001424636.1"
                     /GO_function="GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing protein"
                     /name="nucleotidyltransferase domain-containing protein"
     gene            9994..10698
                     /locus_tag="K6J96_RS27105"
                     /old_locus_tag="TUM12128_52090"
     CDS             9994..10698
                     /locus_tag="K6J96_RS27105"
                     /old_locus_tag="TUM12128_52090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="WP_001067855.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
                     /name="IS6-like element IS26 family transposase"
     gene            <10753..10923
                     /locus_tag="K6J96_RS27110"
                     /old_locus_tag="TUM12128_52100"
                     /pseudo=""
     CDS             <10753..10923
                     /locus_tag="K6J96_RS27110"
                     /old_locus_tag="TUM12128_52100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489893.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /name="serine hydrolase"
     gene            11039..11683
                     /locus_tag="K6J96_RS27115"
                     /old_locus_tag="TUM12128_52110"
     CDS             11039..11683
                     /locus_tag="K6J96_RS27115"
                     /old_locus_tag="TUM12128_52110"
                     /inference="COORDINATES: protein motif:HMM:NF023002.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_228740453.1"
                     /translation="MSFRSTERQTPTPAQVKQRLEEEKRRQQAWDAAHPEEGLKREYDK
                     AKAELDAEDKNIATLNSRIASTEKAIPGARAAVQEADKKVKEAEANKDDFVTYNPPHEY
                     GSGWQDQVRYLDKDIQNQNEKLKAAQTSLNEMNESLSRDKAALSGAMESRKQKEKKAKD
                     AENKLNEEKKKPRKGTKDYGHDYFPDRGSKRESQKIPSFRMMKIQSTPRLT"
                     /name="hypothetical protein"
     gene            complement(11659..13374)
                     /gene="tnpR"
                     /locus_tag="K6J96_RS27120"
                     /old_locus_tag="TUM12128_52120"
     CDS             complement(11659..13374)
                     /gene="tnpR"
                     /locus_tag="K6J96_RS27120"
                     /old_locus_tag="TUM12128_52120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004152391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element Tn4401 family resolvase TnpR"
                     /protein_id="WP_004152391.1"
                     /translation="MKTGQTTASSSTPVGFPDADSLAALRGWYAGLSSRAAVEHYLAAR
                     KAAGQSARGMLGHIRRQLIVFANSRHRPDLADVFQHAPEERQGRAGAVERAIRLLPTLP
                     APKPQISDSIDQWLSPRTVRALQAYGIHTLSALTVRIPRRRGWWKAIEGLGMTGARQVE
                     AFFAAHPQLTERARALIPIIQPSGIVPWEQLRLPNEVDGSQGNFRAPRNACTLNATNDY
                     EAVQAWLALHETVATQRAYRKEAARLILWAIVERGRALSSLTTDDAIAYRAFVRHPTPR
                     ERWVGPPRPRDSVEWRPFSGGLSARSAAYALTVLSALFRWLIEQRYVLANPFAGVKVRG
                     HALRPALDTARGFTEGEWLLLRAIADGLEWSYGWSEPAAQRLRFMLDFGYATGLRASEL
                     VGAVLGNVRLDEHGDHWLHLVGKGGKPGKVALPPLAYTALDQYLAQRQLPVSRERWNPK
                     TPLVGSLGEDGNAGITGPHLWCVLRRFFTQAAEAIEADHPVAAEKLRRATPHWMRHSHA
                     SHALARGAQLTAVRDNLRHASIATTSMYLHGDELERARQMRQAFGARHVKRGVD"
                     /name="tnpR"
     gene            13484..16513
                     /gene="tnpA"
                     /locus_tag="K6J96_RS27125"
                     /old_locus_tag="TUM12128_52130"
     CDS             13484..16513
                     /gene="tnpA"
                     /locus_tag="K6J96_RS27125"
                     /old_locus_tag="TUM12128_52130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004152392.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element Tn4401 family transposase"
                     /protein_id="WP_004152392.1"
                     /translation="MSKKNKLLSVLSDAEQEALYGLPEFDDAQQLEYLAVTETELALAN
                     SRPSLHAKVYCLLQIGYFKAKHAFFSFDWDEVEDDCAFVLSRYFHGEVFEPKAITKHER
                     YTQREQIAKLFGYWPWSAAFLPQLEQQAARTVRRDVTPGFVAAELIVWLNEHKIIRPGY
                     TTLQELVSETLSAERRRLGNLLEQALDESAKAALSQLLVRDDTLSQLAALKQDAKNFGW
                     RQMVREREKRATLEPLHAIAKTLLPKLDVSQQNLLYYASLANFYTVHDLRNLKADQTQL
                     YLLCYAWVRYRQLSDNLVDAMAYHMKQLEDESSAGAKQSFADEQVRRQQETPRVGRLLS
                     LYVDDSVADPTPFGEVRQRAYKIMPRDTLQTTAQRMSVKPASKLALQWQAVDGLADRMR
                     RHLRPLYVALDLSGSNPDSPWLAALAWAKGVFAKQQRLSQRPLDEWPAATLPKRLRPYL
                     LTFDADGKPTGLHADRYEFWLYRQIRKRLQSGELYLDDSLQHRHFSDELVEMDRKIDVL
                     AKMEIPFLQQPVHAQLDALTAELRTQWLAFNRELKQGKLTHLEYNKDTQKLTWRKPKSE
                     NEKAREKAFYEKLPFCDVADVFRFVNDECKFLSAFTPMQPRYAKKVADADSLMAVIIAQ
                     AMNHGNHVMARTSDIPYHVLDSGYQQYLRQATLHAANDCISNAIATLPIFPYYSFDLET
                     LYGAVDGQKFSVERPTVKARYSRKYFGRGKGVVAYTLLCNHIPLNGYLIGAHDYEAHHV
                     FDIWYRNTSDIMPTAITGDMHSVNKANFAILHWFGRRFEPRFTDLNAQLKELYCADDPA
                     QYQACLIRPVGKIDCDLIHREKPNIDRIVATLGLKEMTQGTLIRKLCTYTTTNPTRRAI
                     FEFDKLIRSIYTLRYLRDPQLERNVHRSQNRLESYHQLRSAIAQVGGKKELTGRTDIEI
                     EISNQCARLIANTIIFYNSAILSRLVTKYEAAGNSKALALITKISPAAWRHILLNGHYT
                     FQSSGKTIDLDAIVAGLELE"
                     /name="tnpA"
     gene            16620..17645
                     /gene="istA"
                     /locus_tag="K6J96_RS27130"
                     /old_locus_tag="TUM12128_52140"
     CDS             16620..17645
                     /gene="istA"
                     /locus_tag="K6J96_RS27130"
                     /old_locus_tag="TUM12128_52140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032490293.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="WP_004199214.1"
                     /translation="MLTQEQTVEIRVLARQGHSIRHIARTLGVSRNTVRRYLRDPSVAR
                     YQPREPRPTKLGPFESYLRQRVEQAHPIWLPATVLNREIRAQGYGGGLSLLRAFLATLK
                     PARREAGPAVRFETEPGRQLQADFVVLRRARSPMSAFVATLGYSRMTFVTFVPDESFES
                     VRDSLLLAFDYLGGVPREVLFDNMKTVVLERDAYGDGKHRFHPGLLQLADDLGFRIRLC
                     RPYRAQTKGKVERFNRYFRESFYNPLLTRMKGTGLLLDCAAANRRVRDWLADEANVRVH
                     ATLNERPIDRWRQEREHLQPLPSRVRRDEAPLLDNSLRPVPLESLQHPLSVYDAIGEAC
                     R"
                     /name="istA"
     gene            17642..18421
                     /gene="istB"
                     /locus_tag="K6J96_RS27135"
                     /old_locus_tag="TUM12128_52150"
     CDS             17642..18421
                     /gene="istB"
                     /locus_tag="K6J96_RS27135"
                     /old_locus_tag="TUM12128_52150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004152394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element ISKpn7 family helper ATPase
                     IstB"
                     /protein_id="WP_004152394.1"
                     /translation="MNLQHERIDALCQQLKLERVATHYPVLAQQAVREDFSFTDFLEHL
                     LRHEAGCRQQRSRELLTRMACFPGIKTLEDYDFSFNPGVPKALVQELGSLAFVERAENV
                     VLIGPSGIGKTHLAIALGYKAAQAGVKTRFITAADLMLQLSTAQRQGRLKEYFNRAILG
                     PRLLVIDEIGYLPFGREEANLFFQVVAKRYEKGAMILTSNLPFSQWADAFAGDTTLTAA
                     MLDRLLHHAHILTLSGESYRLKDKRKAGVVRKNSKPE"
                     /name="istB"
     gene            18418..18657
                     /locus_tag="K6J96_RS27595"
     CDS             18418..18657
                     /locus_tag="K6J96_RS27595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004152395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004152395.1"
                     /translation="MIQVGQYYFGDSGVKWVSFQLVLTPAYPRCYLRAPIVGAWPGLPE
                     AVRNVDAEVRRGGRPMNADLIRFSSSVIIPAVAA"
                     /name="hypothetical protein"
     gene            18709..19590
                     /locus_tag="K6J96_RS27140"
                     /old_locus_tag="TUM12128_52160"
     CDS             18709..19590
                     /locus_tag="K6J96_RS27140"
                     /old_locus_tag="TUM12128_52160"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015256839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbapenem-hydrolyzing class A beta-lactamase
                     KPC-2"
                     /protein_id="WP_004199234.1"
                     /translation="MSLYRRLVLLSCLSWPLAGFSATALTNLVAEPFAKLEQDFGGSIG
                     VYAMDTGSGATVSYRAEERFPLCSSFKGFLAAAVLARSQQQAGLLDTPIRYGKNALVPW
                     SPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGPAGLTAFMRSIGDTTFRLDR
                     WELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQQFVDWLKGNTTGNHRIRA
                     AVPADWAVGDKTGTCGVYGTANDYAVVWPTGRAPIVLAVYTRAPNKDDKHSEAVIAAAA
                     RLALEGLGVNGQ"
                     /name="carbapenem-hydrolyzing class A beta-lactamase KPC-2"
     gene            complement(19840..21159)
                     /locus_tag="K6J96_RS27145"
                     /old_locus_tag="TUM12128_52170"
     CDS             complement(19840..21159)
                     /locus_tag="K6J96_RS27145"
                     /old_locus_tag="TUM12128_52170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004152397.1"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element ISKpn6 family transposase"
                     /protein_id="WP_004152397.1"
                     /translation="MAASYLPYRPDQSYLLPPSLGEWLPEGHLAYFISETVDTLDLSAF
                     HARYAGGGPGNQPFHPAMMVKVLIYGYASGVFSSRKLARKLYEDVALRVLAAGNFPAHR
                     TLSDFRALHLTELENLFVQVVQLARECGLVKLGTIAVDGTKVKANASRHKAMSYKRMKP
                     AEDELHCEIKALLDRAKATDDQERNEPELDIPAEISRREKRLEAIQAAKARLEARQREA
                     DQARGRSEDDGRRPRHPDGSDKGGGSYKREFGVPDDRDQESFTDPDSRIMKHAGGGSEQ
                     SYNGYTAVDAEHQIIVAAELTNCAADSQALLGMLAAVQANTGEMPAQTLADAGFRSEAV
                     LAKVADHHGDVIVALGREGREDAKVNAKTHPHTAAIAAKLKTEQGDAAYRRRKSIVEAP
                     NGWIKAVMGLRQFSMRGLDKVQAEWKLVCMALNLRRMAYL"
                     /name="IS1182-like element ISKpn6 family transposase"
     gene            <21512..21772
                     /locus_tag="K6J96_RS27150"
                     /old_locus_tag="TUM12128_52180"
                     /pseudo=""
     CDS             <21512..21772
                     /locus_tag="K6J96_RS27150"
                     /old_locus_tag="TUM12128_52180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000012964.1"
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]; GO:0043022 - ribosome binding
                     [Evidence IEA]; GO:0003723 - RNA binding [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="colicin E3/pyocin S6 family cytotoxin"
                     /name="colicin E3/pyocin S6 family cytotoxin"
     gene            21782..22039
                     /locus_tag="K6J96_RS27155"
                     /old_locus_tag="TUM12128_52190"
     CDS             21782..22039
                     /locus_tag="K6J96_RS27155"
                     /old_locus_tag="TUM12128_52190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cloacin immunity family protein"
                     /protein_id="WP_004152553.1"
                     /translation="MGLKLHIHWFDKKTEEFKGGEYSKDFGDDGSVIESLGMPLKDNIN
                     NGWFDVEKSWVSILQPHFKNVIDISKFDYFVSFVYRDGNW"
                     /name="cloacin immunity family protein"
     gene            22124..22273
                     /locus_tag="K6J96_RS27160"
     CDS             22124..22273
                     /locus_tag="K6J96_RS27160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891188.1"
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="WP_004152552.1"
                     /translation="MKKVKVVFLFILIFSGFLLVACQANYIRDVQGGTVAPSSSSELTG
                     IAVQ"
                     /name="colicin release lysis protein"
     ARG             18710..19587
                     /name="blaKPC-2"
                     /gene="blaKPC-2"
                     /gene_name="carbapenem-hydrolyzing class A beta-lactamase
                     KPC-2"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             9726..9982
                     /name="aadA15"
                     /gene="aadA15"
                     /gene_name="ANT(3'')"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="97.14"
                     /coverage="32.32"
     ARG             9039..9643
                     /name="AAC(6')-Ib10"
                     /gene="AAC(6')-Ib10"
                     /gene_name="AAC(6')"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="98.97"
                     /coverage="99.01"
     Typing          complement(22377..22955)
                     /name="ColRNAI_rep_cluster_1857"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="95.361"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          1966..2693
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="1.3599999999999998e-150"
ORIGIN
        1 atgtttaata cggattcgct tgcctggaag tggcacattc cggagctggc ccggcagatt
       61 tatccgtggg tcagctggct gtaccaggag tattacggtc tggccggggc tttcctagtt
      121 atcggcctgt ttttcggtct ggctgaactt tgggccggac ggatgcgttt tgtggggctg
      181 agtcataagg agcgacggga gtatgccgat cgctataagc gcgataataa acggccagcg
      241 ccattttcgg tgctggcctc gctggattcg cccgggcgga tggtcagggc acgtcgacat
      301 gtctggaact acgcgtactg gctgaccggc gcggccggtc tggcccttct gggggggctg
      361 gttgtcgccg tgtttatcga gagctgggga gaaaccgtcc tgcgtccgga cctctacgca
      421 aacgcagatt attacctgct gcagccggct aacctgttcg ggattgcctg gtgcgcgggc
      481 gggctggctg tcgggattgt gttggcgcgg ctgctggcgt tcctgctgct tgacggtcat
      541 tttgcggctg ctgacgaggc ggtgaacgcg aaactgaatc aggagagccg gcgcagcagc
      601 cagcggacag gagagatgac cgacgtgcgc cacctgcatt tcggggagcc ggtaccggtt
      661 aatgcgctgg ccgatttttc ctcggagcag gcccggcagg agcaggcggt gtttctgggt
      721 aaggatgagc agggcaagcc ggtgctggtt ccgcgtgata cctggcgcaa gaccaacatt
      781 cagatcctcg gcctgcccgg gagcggcaag agcgtgatgg ccaccaacgc gctcattcgc
      841 tgcgtacgcg atttcgggga cgcggtggtg tacttcgacc ccaaagggga cgcatgggcg
      901 ccgcacgtct tccgggcgca ctgtccggac ttcaccctgc tggatctgcg gccggggaaa
      961 ccggcgcagc tgaatctgtt ccgcgatctc gaccagtacg cgctgaaaaa cctgctgatt
     1021 gccgggctta acctgggcga gaccggcgac gtggcggacc actaccgcat cagcgagcag
     1081 aaagcggcga agctgattgc ggagcagttt ccgcaggggg caaacattca gcaggtgctg
     1141 gcggcggcgt acgcgctgcc ggaggccctg aaaaaggacg tgaaggggtt gatcactagg
     1201 ctggaaaacg tcgctgacct gagcgtcctg cagacggaca gtggcatcga tgtggcgggg
     1261 attatcaacg gcggcggctg cctgtacgtt atcggctcga tggacgacga ggcggtgatc
     1321 cgtgtgcaaa aaatgctgtt tgcccgctgc gcgcaaatca tcattgcgcg ggacgagttc
     1381 cgggagtggc cacacgtcag cgtgatgctc gatgaaatta aatatctgct gtcgaagtat
     1441 gtactgaacg cactggggac gctgcgcagc cgggactgca atctgttgct cgcgcaccag
     1501 tcgctgggcg atttcgggca gtgcgggcag gatctgcccg ctgaatttgt gaaaaccacg
     1561 gtactggata acacgccgat ccgctggttt taccgggcgg ccagcctgga gtccgcgcag
     1621 tgggcggcgg ggcagaccgg ggaaatcagg gtggacgtgg agcgccgccg tgccagccgg
     1681 gaggcgggga acgtggagca tatcagcggg gacagcttca tccagaagga ggcgcggccg
     1741 ctgtttgacg tgaacaccct gcaacacctg ccggacgggt tcgcggtcat gaccgggctg
     1801 ggtgtggccc ggatggcgtt cagcagtccg ctgcgggttg agcgccggga aatcccgttg
     1861 cagcgtttcc cggtgctggc gaaaaccgat cccctggcgg agttccggcc cccggccgac
     1921 ggcggcgggc cgaaagcgga tgatgatttt gcggggattt actgatggcg ctggagctgt
     1981 acaacgtcag ccacgcgaaa cgacaggcgc ggaacgcgga gaaaacccgg ctgaccctgc
     2041 gctggttgcg ggaagagctg tgttccacgg cggagctggt tgcgcggcgg ctggggattg
     2101 cggcggtgca gccggtctac cgcttcctcg acagcctggt ggcgaaaggg ctgctggtcc
     2161 ggaccaaata tccggtggac ggccgtcagg tcagcgtgtg ggggctgacg ccgcatggcg
     2221 tggcgttctc gttcgacgag gacgaaccgc tggcggatgt tattccgttt cagccgtcaa
     2281 gggtgtcggc agcacatctg ccgcaccggc tggccgtgca atccctgcgc cttgatatgg
     2341 aagccagagg ggccaccggc tggcgcattc tgcaccgtct gagtcttaaa ggcatgaaag
     2401 tgccggacgc cctggcggag ctggacggta aaacggtggc gtttgaggtg gagcgcaccg
     2461 tcaagagccg tcgccggtat caggaagtgg tgtccgggta tctgttcaac cgcaaagcta
     2521 acggcatcga tgaaatctgg tacatctgcc cggaccgggc gacgcaggtc agggtgcagc
     2581 gggcaatcct gtcggtggat gaaatcgtga acccacagac cggcgaggcc cgcaaaacgg
     2641 cagagctgga tcgtgaacgg ttgtttgcgt gctttaaatt tatgacaacg gagtgaggga
     2701 ttatggcgct gtacatggta tttattgaag acgcggagga ccggaacggc gagcgctgca
     2761 tcatgccgac cagcgagcat ctggaagata tggtggtgct cgcctggcag accggggcgt
     2821 atgttttctg ttttgtcgac cgggcccagc atctggcgat gatgaaatcc atcgggatgt
     2881 atgacgagcg gctcaacagc gacgaaaaag ccacgtactt tttcactggt aaaaatccgc
     2941 aatgggaacg gaacaaaccc acaggaatga agctgtgtga ttacctctat cgcaaggtgg
     3001 agcggttcgc catcgagaac ggtgtgcagg tggttgatgc cgggaagtgc tcaccggagc
     3061 agattaacgc gatgattgac gtggtgagtg agcggcacgg ggaaagcgcg gtgaacgaga
     3121 agctgaaagc ggagctgatg cgggaatata acagccgcta ttttaacgtg ccggtacctg
     3181 aactgccgga ggacaaacct gcccgccggt ggtggccgtt cggcaaaaaa taaatgccag
     3241 caccggccat gccggtgctg ttattcctcc ccgagcttat cccgcatcac ctgccagagt
     3301 gtttccgcat cctcgtgtag ccgctcgcac atgtcggccg gggtatccat atccagctca
     3361 ttcagtttat cgagcaatag cagcgactgc tccttaataa atttagccat attgagggct
     3421 gttttttcct gttttgtcat gattctttcc ttccgggcat ggtgtgcgcc tgtcaggtat
     3481 actgtctcaa aaatagcggg gtgagacaat ggcgtgggtg acggtgagac aggcgacgga
     3541 actgacgggt aaagcccgaa gttccctgta tcgggatatg gcgaaaggcc gcgtatcata
     3601 ccgtacggaa gctgatggcg gccgggtggt ggataccagc gagcttatcc gggtgtacgg
     3661 tgagttaaga caggatgaga ctcacgagcg ggacgagttg agactgtcgg gtgagactga
     3721 aaaaatggcc tccgacgcgt tgatcgcgga gataaaagca ctcagggagg aggtggccgg
     3781 gctacggcag gaaatgcagt ccatgagact gctggaacac aaaccggaga cagcagagac
     3841 cccggccgga acaccgcgcc ggtggtggcc gtggggaaaa cgctgacgcg ctgtgcttgt
     3901 ccaaccggcg acggccacgc aatgaattgc gtccccgtca ccggttatta gagaacaata
     3961 tggggattct ggcgctggcc gaccacggcc agaacccgga cttttctggt ctggtcatca
     4021 acatcataga ggacatgctg tcccatcaga ctgatccggc gaacgtcctc gccatagcgt
     4081 gagtccactt catagagtcg cgggaagtcg gccagtttgt ccgccgcagc gagaacccgg
     4141 tcggtaacgt tctgcgcatc ccacagggat gaattttccg cgatatagtc aaacagcgtc
     4201 gttacatcct cgatggctcc ctgcttccat tccacgtcat acggcatcgc gcagttcctg
     4261 ataacggcca tgcaggcgct ggcggagttg ttccgtggtc atacccggac gcgtgtcagc
     4321 acgggcggcg gtcactttgg cgcgaacctg atcttcatac tctgcctggg ccagttcttc
     4381 gttagccagt cgctgcaaca gcgcagcttt gtccgggcca ccttccggca gtatgcgggg
     4441 caggctttca gccagttccc gaagaaagtt ggcgttttcg tagtgtgtag tgttgctcat
     4501 tgcggagcct cccgggttaa tgcggcaata tgaaggaagt ttagcagggg gcggtctgaa
     4561 agaatatggt cgtgtcagtc aggctgatga agcagaaagt cggtaaaaaa gggcttacgg
     4621 catccatttt acgtcaaaac atatgccatg cagttgcgtg cataggcatg cattaggata
     4681 aaatttatcg ggcgcgtttc cggcagtttt ccgggggggt tgttgcctgt tttatcccgt
     4741 agccgccgga aacgccctga gcccgtctga gcggtgcgcg taatgacgcg ttatggtaaa
     4801 tccacttact gtctgccttc atagccatcg agataaacag ctgaaatggt gtcagccagt
     4861 agccttgatt ttttcggtgt gaggtctttg ctgcggtaat cggtacccgc aaattgtgtt
     4921 gtgccttgga gtgagtttaa aaattcctga ctgtgaaact gctgaatgcg ttgctgcaca
     4981 tcactccgtg attttccggt cgctttatcc tttgcgccca tatcccagaa ctgccggaaa
     5041 aaaggcacca tcattcgtgt tgtgtcagct ttctgggtgg aaaaattggg atcaaaaggg
     5101 gtctgacgct cagtggaacg aaaactcacg ttaagcaacg ttttctgcct ctgacgcctc
     5161 ttttaatggt ctcagatgac ctttggtcac cagttctgcc agcgtgaagg aataatggcc
     5221 gagcatattg atatgtccgt ggcaaagcgg ggagaggcgt gcgatatctt catcattcag
     5281 tgtttcaccc tgcgcccgga gatgatccag agctgcctgc atataaatag tgttccataa
     5341 cacgacggcg ttagtgacca gccccagagc tcccaactga tcttcctgac cgtcggtata
     5401 tcgttttctt atctcacctt tttgaccgtg acagatggct ctggcaactg catgacggct
     5461 ttctccccga ttaagctggg tcagaatgcg ccggcggtaa tcttcatcat caatataatt
     5521 aagcagatac agcgttttgt tgatgcgccc cacttcaatg attgcctgag tcagtccgga
     5581 gggacgttca cttttcagca atgaacggac cagcactgag gcctgtactt tgcccagctt
     5641 cagggagcct gcggtccgga tcatttcgtc ccactgaagg actatttttc ggggatctga
     5701 ttgccctctg gcaatatcat tcagcacgcc atagtcggca tcatggtcca ttcgccagaa
     5761 aaccgaagca ccggcatcag ccaggcgtgg agaaaactgg tatcccagca gccagaaaag
     5821 gccaaagaca agatcgctgg cacctgccgt atcggtcata atttcggttg gattcagccc
     5881 ggtctcctgt tccagaaggc cttccagcac aaagatagag tccctcagcg tccccggtat
     5941 aacgatgcca tgaaagccgg aatactgatc ggacacaaag ttgtaccagg tgatccctct
     6001 gttattacca aagtatttgc ggttcggtcc ggcattgatt gttctgactg gcgtaacaaa
     6061 gcgcattcca tctgcagatg ccacttctcc tccaccccat atctgtgcca gtggcagcgt
     6121 tgcctgaaaa tcaaccagtc tggcattagc gctggtgata gtttcagccc gcagatagtt
     6181 cgcttttgtc cagttcagcc ggtgtcgggt cagtgcagga acatttgatc tgatcagtgg
     6241 ttccagaccg atattgcagg cttcagccat cagcacggcg ctgatgctga cgggcagatc
     6301 atcaactctg gcactggctt cactggcatg gaaaaactca tcagcaaatc cggtatgggc
     6361 gttaatttcg agcagcaact ccgttaaatc caccggaggg agcagatcac tgatcatttt
     6421 gctcagtcgt ttcagactgt ccggctcatc aagactggcg aggggagaaa ttgtcaaccg
     6481 gggcttcggg ccagaaacat cgagttcgac agcctcattt tcgccaagac gtgcagcaac
     6541 ctgtctgtaa cgactatcaa gctgatggcc cagagatttt attgcttcct gcgggtctgt
     6601 cgggtgcccc aaagaacgat aaaccttaat ccgatttgcc tgccagtcag caccctgtag
     6661 taatcttgca cgaggatctc cccaccggtt actgccggta acgtagacat ccctccgtct
     6721 cagactatcc tgcagtttac tgagaaagca gagcgtgtat ccccttcggg tgatatgttt
     6781 ttccttgtta atcaccagcc gtttccatga ctgactgatg atttccgttg gtgcgtcgtc
     6841 aaaaaactgc cgccgtgagc tgaactcccg gctgaggtag tcacaggcat tcagagtggt
     6901 aaccccggca ggtgcggatg aaaatttaac ggtattcagc agatggggca ggaaacgacg
     6961 aacgcgcccg tactgctcca ccatttcgtc atgaaaatta tcgtctgagg gccgggcaat
     7021 ttcacggaca agcgtgatga tttcagccag cttttgccta gggatgtagc tgaacacctc
     7081 agcacgaatc gattcgtccg gtgtttcttc tttcagcaag tacgaacatg cgctggcgag
     7141 cgccaatgca gatttatcca gatccttcag cgagcggagc cgttttttct gcccaatctt
     7201 tctggcgtca cggatgataa cggccagcat ggcgtccaga acgtccagtg catcatccag
     7261 cgccagcgtt tcccatgcaa ggacaaaggc aaccagaacc gccatccttt tctgcggtga
     7321 catcctggca atattgaaca ccgaagtcat accagcataa cgtgcgagat ttttcaggcg
     7381 cacagccggg agtgtactca ggttttcagc atgcaggcca aaatcgttca gagttttcca
     7441 gcgttcaatt gcttcattaa acgccggacc actgatggtc acagggcctt ttttcagtga
     7501 ttccagtaaa gacaggcggc tgcaatcagt tggccccagc agcatctcca gctgtgaacg
     7561 ctgttcggct gacggtatca gtgccagttt gttccacagg cgcaacgtcg ccttttccct
     7621 tacctctgaa atcaaccggg tcagcgtggt ggctccgggg agaataatac gatgttgcat
     7681 aagccaccct gtcgccaggt cgaaaagcag gccaggacgt tcgttgctta tccagctccg
     7741 ggtatataaa agacgggtaa ggcgaaatgt ccagggccag gcaaattcac gatactgata
     7801 gtgctgacgt atcagcgctg catgctcacg gcgggtattt tccctctgac cgtattctgc
     7861 aagaacggtg atatcacgaa tcccgagctg tctggcggta aaatgccgga cgccggaagg
     7921 aatatgattc atgtcagtaa gaaaagtgcc cagaaaacgc acacacccga tttgcagggc
     7981 aataccaagt cgattgtgat caccccggct tttcccgata aattctttat ccgcttcatc
     8041 aagatgaaaa taacgcgcca gctgaagttc atcgggttcg ccagtgaacc tgccataact
     8101 ctcaacctgc tcagtggtca aaaaatcaac gggcatatcg gcctccctgc ctgacggctt
     8161 ttttaacaca actgcaaccg ttcgaaatat tataaattat cagacatagt aaaacggctt
     8221 cgtttgagtg tccattaaat cgtcattttg gcataataga cacatcgtgt ctgatattcg
     8281 atttaaggta catttttatg cgaatttttg gttatgcgcg ggtctcaacc agccagcagt
     8341 ccctcgatat tcagatcaga gcgctcaaag atgcaggggt aaaagctaac cgcatcttta
     8401 ccgacaaggc atccggcagt tcaacagatc gggaagggct ggatttgctg aggatgaagg
     8461 tggaggaagg tgatgtcatt ctggtgaaga agctcgaccg tcttggccgc gacaccgccg
     8521 acatgatcca actgataaaa gagtttgatg ctcagggtgt agcggttcgg tttattgacg
     8581 acgggatcag taccgacggt gatatggggc aaatggtggt caccatcctg tcggctgtgg
     8641 cacaggctga acgccggagg atcctagagc gcacgaatga gggccgacag gaagcaaagc
     8701 tgaaaggaat caaatttggc cgcaggcgta ccgtggacag gaacgtcgtg ctgacgcttc
     8761 atcagaaggg cactggtgca acggaaattg ctcatcagct cagtattgcc cgctccacgg
     8821 tttataaaat tcttgaagac gaaagggcct cgtgatacgc ctatttttat aggttaatgt
     8881 catgataata atggtttctt agacgtcagg tggcactttt cggggaaaag tgcgcggaac
     8941 ccctatttgt ttatttttct aaatacattc aaatatgtat ccgctcatga gacaataacc
     9001 ctgataaatg cttcaataat attgaaaaag gaagagtatg agtattcaac atttccaaac
     9061 aaagttaggc atcacaaagt acagcatcgt gaccaacagc aacgattccg tcacactgcg
     9121 cctcatgact gagcatgacc ttgcgatgct ctatgagtgg ctaaatcgat ctcatatcgt
     9181 cgagtggtgg ggcggagaag aagcacgccc gacacttgct gacgtacagg aacagtactt
     9241 gccaagcgtt ttagcgcaag agtccgtcac tccatacatt gcaatgctga atggagagcc
     9301 gattgggtat gcccagtcgt acgttgctct tggaagcggg gacggatggt gggaagaaga
     9361 aaccgatcca ggagtacgcg gaatagacca gttactggcg aatgcatcac aactgggcaa
     9421 aggcttggga accaagctgg ttcgagctct ggttgagttg ctgttcaatg atcccgaggt
     9481 caccaagatc caaacggacc cgtcgccgag caacttgcga gcgatccgat gctacgagaa
     9541 agcggggttt gagaggcaag gtaccgtaac caccccagat ggtccagccg tgtacatggt
     9601 tcaaacacgc caggcattcg agcgaacacg cagtgttgcc taacccttcc atcgaggggg
     9661 acgtccaagg gctggcgccc ttggccgccc ctcatgtcaa acgttaaaca tcatgaggga
     9721 agcggtgatc gccgaagtat cgactcaact atcagaggta gttggcgtca tcgagcgcca
     9781 tctcgaaccg acgttgctgg ccgtacattt gtacggctcc gcagtggatg gcggcctgaa
     9841 gccacacagt gatattgatt tgctggttac ggtgaccgta aggcttgatg aaacaacgcg
     9901 gcgagctttg atcaacgacc ttttggaaac ggcactgttg caaatagtcg gtggtgataa
     9961 acttatcatc cccttttgct gatggagctg cacatgaacc cattcaaagg ccggcatttt
    10021 cagcgtgaca tcattctgtg ggccgtacgc tggtactgca aatacggcat cagttaccgt
    10081 gagctgcagg agatgctggc tgaacgcgga gtgaatgtcg atcactccac gatttaccgc
    10141 tgggttcagc gttatgcgcc tgaaatggaa aaacggctgc gctggtactg gcgtaaccct
    10201 tccgatcttt gcccgtggca catggatgaa acctacgtga aggtcaatgg ccgctgggcg
    10261 tatctgtacc gggccgtcga cagccggggc cgcactgtcg atttttatct ctcctcccgt
    10321 cgtaacagca aagctgcata ccggtttctg ggtaaaatcc tcaacaacgt gaagaagtgg
    10381 cagatcccgc gattcatcaa cacggataaa gcgcccgcct atggtcgcgc gcttgctctg
    10441 ctcaaacgcg aaggccggtg cccgtctgac gttgaacacc gacagattaa gtaccggaac
    10501 aacgtgattg aatgcgatca tggcaaactg aaacggataa tcggcgccac gctgggattt
    10561 aaatccatga agacggctta cgccaccatc aaaggtattg aggtgatgcg tgcactacgc
    10621 aaaggccagg cctcagcatt ttattatggt gatcccctgg gcgaaatgcg cctggtaagc
    10681 agagtttttg aaatgtaagg cctttgaata agacaaaagg ctgcctcatc gctaactttg
    10741 caacagtgcc ctgataaatc tggagccggt gagcgtgggt ctcgcggtat cattgcagca
    10801 ctggggccag atggtaagcc ctcccgtatc gtagttatct acacgacggg gagtcaggca
    10861 actatggatg aacgaaatag acagatcgct gagataggtg cctcactgat taagcattgg
    10921 taactgtcag accaagttta ctcatatata ctttagattg atttaaaact tcatttttaa
    10981 tttaaaagga tctaggtgaa gatccttttt gataatctca tgaccaaaat cccttaacgt
    11041 gagttttcgt tccactgagc gtcagacccc tactccggca caggtaaaac agcgtctgga
    11101 ggaagaaaag cgtcgccagc aggcatggga cgctgctcac ccggaagagg ggctgaaaag
    11161 agagtatgat aaagcgaaag ctgagctgga tgctgaagat aaaaatattg cgaccttaaa
    11221 cagtcgcatt gcatcgacag agaaggcgat ccccggtgca agggctgctg ttcaggaagc
    11281 cgataaaaag gtaaaagagg cagaggcaaa taaagatgat tttgtgactt ataacccgcc
    11341 tcatgaatat ggctccgggt ggcaggatca ggttcgctat cttgataagg atattcagaa
    11401 tcagaatgag aaattaaaag ctgcccagac atctttaaac gaaatgaatg aatccttatc
    11461 cagggataag gctgcgcttt ccggggcgat ggagagccgg aaacaaaagg agaaaaaagc
    11521 gaaggatgca gaaaataaat taaatgagga aaagaaaaaa cctcgtaagg gaactaaaga
    11581 ttacggccat gattattttc ctgatcgggg ttctaagcgg gaatcccaga aaattccgtc
    11641 attccgtatg atgaaaattc agtcgactcc tcgcttgacg tgacgagcgc caaaagcctg
    11701 ccgcatctgc ctggcgcgct cgagctcatc gccatgcaaa tacatcgacg tcgtggcgat
    11761 cgacgcatgg cgtaggttgt cgcgcaccgc ggtgagctga gctccccggg ccaacgcatg
    11821 gctggcatga ctgtgacgca tccaatgagg cgtggcacgg cgcagctttt cggcggcgac
    11881 cggatgatcg gcctcaatgg cctcagcggc ttgcgtaaag aatcttcgca acacgcacca
    11941 aaggtgaggg ccggtgatgc cggcattacc gtcttcccca agactgccca ccaggggcgt
    12001 tttcggattc caccgttccc ggctgactgg cagttgacgc tgtgccaagt attggtccag
    12061 cgccgtatac gcgagcggcg gcaaggccac cttacctggt ttgccacctt tgccaaccaa
    12121 atgcagccag tggtcaccgt gctcgtcgag gcggacatta cccaggacgg cgccgaccag
    12181 ttcgctagcg cgcaggcccg tggcatagcc gaagtcgagc atgaagcgca ggcgttgtgc
    12241 tgccggctcg gaccagccgt aggaccattc caggccgtct gcaatggcgc gcagcagtag
    12301 ccattctccc tcggtaaagc ctcgcgccgt atccagtgcg ggccgcaagg cgtgaccgcg
    12361 taccttgacg ccggcgaaag ggttggccag cacatagcgc tgctcgatga gccaccggaa
    12421 cagcgccgag agcaccgtca gcgcatacgc tgccgagcgt gcggacaagc cgcccgagaa
    12481 ggggcgccat tccaccgaat cgcgtggtcg aggtggcccc acccaacgct cgcgcggggt
    12541 cgggtgccgg acaaaggccc ggtacgcgat tgcatcgtcc gtggtcaggg atgatagcgc
    12601 ccgtccgcgt tcgacgatgg cccacaggat tagccgcgca gcctccttgc gataggcgcg
    12661 ctgtgtggcg acagtctcgt gcagcgccag ccaggcctgc acggcctcgt agtcgttggt
    12721 cgcattcagc gtgcaagcgt tgcgcggggc ccggaaattg ccctgcgagc cgtcgacttc
    12781 gttcggcaga cgcaactgct cccacggcac gatgccgctg ggctgaataa tcgggatcag
    12841 ggcccgggcg cgctcggtga gctgcggatg tgcggcaaag aaagcctcga cctgccgggc
    12901 gcctgtcatg ccgagtccct cgatggcttt ccaccagcca cgccggcggg gaatgcgcac
    12961 ggtcagcgcc gagagggtgt ggataccgta cgcctgcagt gccctgacgg tcctcggaga
    13021 cagccactgg tcgatgctgt cgctgatctg gggcttcggc gccggcagcg tgggcaagag
    13081 ccggatcgcg cgttcgacgg cacccgcgcg cccctgtcgc tcttcggggg cgtgctggaa
    13141 cacgtcggcc agatccggcc ggtggcggct gttggcgaaa acgatgagct ggcggcggat
    13201 atgccccagc atccctcgcg ctgattgacc ggcggccttg cgtgccgcca ggtagtgttc
    13261 aacggccgcg cgagagctga gtcccgcgta ccagccgcgc aaggcagcca gcgaatccgc
    13321 atcgggaaag ccgactgggg tagaactcga agccgtagtc tggcccgttt tcatatggac
    13381 aggttgcgat tcgaaaagcg agtaacgcga taataacgat tatttcagta gaatcgaaaa
    13441 tgccccatgt ttctacgaaa cctcaagata gcaagaacgg gccatgagca agaagaacaa
    13501 gctactcagc gtcctatccg acgccgaaca ggaggccttg tatggcctgc cggagttcga
    13561 tgatgcgcag cagctggaat atctggctgt gacagaaacc gagttggcgc ttgccaacag
    13621 ccggcccagt cttcatgcca aggtctattg cctcttgcag atcggctact tcaaggccaa
    13681 gcatgccttc ttcagtttcg actgggacga agtcgaggac gattgcgctt tcgtgctgag
    13741 ccgctatttc cacggcgagg tgttcgaacc caaggcgatc accaagcatg aacgctacac
    13801 ccagcgcgag cagatcgcca aactattcgg ctactggccg tggtcggccg ccttcctgcc
    13861 gcagctcgag cagcaggccg cacggaccgt gcggcgtgac gtaacgccgg ggttcgtcgc
    13921 cgccgagctg atcgtctggc tcaatgagca caagattatc cggcccggct atacgacctt
    13981 gcaagagttg gtcagcgaaa cgctatccgc cgagcgccgg cgcctgggca atctgctgga
    14041 gcaagcgttg gacgaatctg ccaaggccgc gctgagccag cttctggtcc gtgatgacac
    14101 cctgtcgcaa ctggcggcgc tcaagcagga cgccaagaat ttcggctggc gccagatggt
    14161 ccgcgagcgc gaaaagcgcg ccacgctgga gccgctgcac gcaatcgcca agacactgct
    14221 gcctaaactc gacgtctcgc agcagaacct gctgtactac gcgagcctgg caaacttcta
    14281 caccgtccac gacctgcgca atctgaaggc cgatcagacc caactctacc tgctgtgcta
    14341 tgcctgggta cgctaccggc agctctccga caacctggtc gatgcgatgg cgtaccacat
    14401 gaagcagttg gaggacgaaa gcagcgctgg tgccaaacaa tcctttgccg acgagcaggt
    14461 gcgccgtcag caggaaacgc cgcgggtagg ccgcctgctg tcactctacg ttgatgatag
    14521 cgtggccgat cccacgccct tcggcgaggt gcggcagcgc gcctacaaga tcatgcctcg
    14581 cgatacgctg caaaccacgg cgcagcgtat gagcgtgaag ccggcgagca agctggcctt
    14641 gcagtggcag gcggtggacg ggctggccga ccgcatgcgc cgccatcttc gtccactgta
    14701 cgttgcgctc gacctctccg gctccaatcc agacagtcca tggcttgccg cgctggcctg
    14761 ggccaaaggt gtttttgcca agcagcagcg gctgtcgcaa cggccactcg acgagtggcc
    14821 cgcggcgaca cttccgaaac gcttgcggcc gtacctgctg accttcgacg ccgacggtaa
    14881 accaaccggc ctgcacgctg accgctacga gttctggctg taccgccaga tcaggaagcg
    14941 tctccaatcg ggtgaactct acctcgacga cagcctgcaa caccggcact tctcagatga
    15001 actggttgag atggacagga agatcgatgt gctcgcaaaa atggagatcc ccttcctgca
    15061 gcaacccgtc catgcccaac tcgatgcgct gactgccgaa ctgcgcacgc agtggctggc
    15121 gttcaaccgc gagctgaaac agggcaagct gacgcacctc gaatacaaca aggacacgca
    15181 gaaactgacc tggcgcaagc ccaagagcga gaatgagaaa gcgcgcgaaa aggcattcta
    15241 cgagaagctt ccgttctgcg acgtggccga cgtgtttcgc ttcgtcaacg acgagtgcaa
    15301 gtttctgtcg gcgttcacgc ccatgcagcc gcgctacgcg aagaaggtcg ccgacgctga
    15361 cagcctgatg gcggtcatca tcgcgcaagc gatgaaccac ggcaaccacg tcatggcgcg
    15421 caccagcgac atcccgtacc acgtgctgga tagcggctac cagcagtacc tgcgccaggc
    15481 aacgctgcac gcggccaacg actgcatcag caacgccatc gccacgctac cgatcttccc
    15541 atactactcg ttcgacctcg aaacgctgta cggtgccgtc gacgggcaga aattcagcgt
    15601 cgaacggccg accgtgaagg cgcgctattc gcgcaagtac ttcgggcgcg gcaagggcgt
    15661 ggtcgcctac acgctgctgt gcaaccacat cccgctcaac ggctacctga tcggcgcgca
    15721 cgactacgag gcccaccacg tgttcgacat ctggtatcgc aacacgtcgg acatcatgcc
    15781 gaccgcgatc accggcgaca tgcacagcgt caacaaggcc aacttcgcca tcctgcattg
    15841 gtttggccgg cggttcgagc cgcgcttcac cgacctcaac gcgcaattga aagaactcta
    15901 ctgcgctgac gatccagcac agtatcaggc gtgcctgatt cggccagtcg ggaaaatcga
    15961 ctgcgatctc atccatcgcg agaagccgaa catcgaccgg atcgtcgcca cactcgggct
    16021 gaaggaaatg acgcagggca cgctgatccg caagctgtgc acctacacca cgacgaaccc
    16081 gacgcggcgc gcgatcttcg agttcgacaa gctcatccgc agcatctaca cgcttcgcta
    16141 cctgcgcgat ccgcaactgg aacgcaacgt gcaccgctcg caaaatcgcc tcgagtccta
    16201 ccatcagcta cgctcggcca ttgcccaggt cggcggtaag aaggaactga ccggtcgcac
    16261 cgacattgaa atcgagatca gcaaccagtg cgcacggctg atcgccaaca cgatcatttt
    16321 ctacaactcg gcaatcttgt cgcggctggt gaccaagtac gaggcggccg gcaacagcaa
    16381 ggcgctggca ctcatcacaa aaatttcgcc tgcggcatgg cggcacatcc tgctcaacgg
    16441 gcactacacc tttcaaagca gcggcaagac gatcgatctc gatgcgatcg tcgcaggcct
    16501 ggaactggag tgacggaatt ttcagcggtt ccgtgttagc agcagtgtaa aactgaccca
    16561 ccccagcgaa gtaaaactga tccacctggg ctagtttggc ggccttttcg aggccgtcga
    16621 tgttgaccca ggagcaaacc gtggaaatca gagttcttgc ccgacagggc cactccatcc
    16681 ggcacatcgc ccgcacgttg ggggtctcgc gcaataccgt gcgccgctac ctccgcgatc
    16741 cgtcggtagc gcgataccag ccccgtgaac cacgccccac caaactgggg ccatttgaat
    16801 cttatctgcg gcaacgggtc gagcaggccc accccatctg gctgcctgcc accgtcctga
    16861 atcgggaaat ccgcgctcaa gggtatggcg gcggtctctc gttattgcgc gccttcctcg
    16921 ccacgctcaa gcccgcccgc cgcgaagcag gtccggccgt ccgtttcgag accgagcccg
    16981 gacggcagtt gcaggctgat ttcgtggtct tgcgccgggc cagatccccc atgtcggcct
    17041 tcgtcgccac gctgggatac agccgcatga cgtttgtcac cttcgtaccg gacgaatcct
    17101 tcgagtccgt gcgggactcc ctgttgctgg cttttgacta tctgggcggt gtgccccgcg
    17161 aggtgttgtt cgacaacatg aagaccgtgg tgctggaacg cgatgcctac ggtgacggca
    17221 agcaccgttt tcaccccggc ttgcttcaac tggccgatga cctggggttc cggatccggc
    17281 tgtgtcgccc gtatcgggcc cagaccaaag gcaaggtcga gcgcttcaat cgctacttcc
    17341 gcgagagctt ctacaacccg ttgctgaccc ggatgaaggg cacggggctg ctgctcgatt
    17401 gtgctgctgc caaccgacgc gtccgtgact ggttggcaga cgaggcgaat gtgcgggtcc
    17461 acgccaccct gaacgagcgc cccatcgacc gttggcggca ggagcgggaa cacctgcaac
    17521 ccttgccatc ccgtgtgcgg cgcgacgagg cccccctgct ggataacagt ctccgcccgg
    17581 taccactgga atctctccag cacccactgt ctgtctatga cgcaattggg gaggcctgcc
    17641 gatgaacctc cagcatgagc ggatcgacgc cctgtgccag caactcaaac tcgaacgggt
    17701 ggcaacgcat taccccgtcc tggcgcagca ggcggtgcgc gaggacttca gcttcaccga
    17761 cttcctggaa cacctgttgc ggcatgaagc ggggtgtcgc cagcagcgca gccgcgaact
    17821 gctgacgcgg atggcttgct tcccgggcat caagaccctg gaggactatg acttcagctt
    17881 caaccccggc gtgcccaagg cactggtgca ggagctgggc agtctggcgt ttgtcgaacg
    17941 ggccgagaac gtggtgctga tcggaccctc tggcatcggc aagacccacc tcgccatcgc
    18001 cttgggttac aaggccgcgc aagccggggt caagacacgc ttcatcacgg cagccgacct
    18061 gatgctgcaa ctgagcacgg cgcagcgaca agggcggctg aaggaatact tcaaccgcgc
    18121 catcctcggt ccacggctgc tggtgatcga tgagatcggc tacctgcctt tcggacgcga
    18181 ggaagcgaac ctgttctttc aggtggtggc gaagcgctat gagaaagggg cgatgatcct
    18241 gacctcgaac ctgccgttca gccagtgggc cgacgcgttt gccggcgata ccaccctgac
    18301 agccgcgatg ctggatcggc tgctgcacca tgcccatatc ctgaccctga gcggcgaaag
    18361 ctaccgcttg aaggacaaga ggaaggcggg agtggtcagg aaaaattcca aacccgaatg
    18421 atccaggtgg gtcagtatta ctttggtgat tcaggggtaa agtgggtcag ttttcagttg
    18481 gtgttgacac cggcgtaccc tcggtgctat cttcgcgccc caatagtcgg ggcttggcca
    18541 ggacttcctg aggccgtccg taacgtggat gccgaggtca ggcgaggtgg ccgacccatg
    18601 aacgccgacc tgattcgttt ttcaagctcg gtgataatcc cagctgtagc ggcctgatta
    18661 catccggccg ctacacctag ctccaccttc aaacaaggaa tatcgttgat gtcactgtat
    18721 cgccgtctag ttctgctgtc ttgtctctca tggccgctgg ctggcttttc tgccaccgcg
    18781 ctgaccaacc tcgtcgcgga accattcgct aaactcgaac aggactttgg cggctccatc
    18841 ggtgtgtacg cgatggatac cggctcaggc gcaactgtaa gttaccgcgc tgaggagcgc
    18901 ttcccactgt gcagctcatt caagggcttt cttgctgccg ctgtgctggc tcgcagccag
    18961 cagcaggccg gcttgctgga cacacccatc cgttacggca aaaatgcgct ggttccgtgg
    19021 tcacccatct cggaaaaata tctgacaaca ggcatgacgg tggcggagct gtccgcggcc
    19081 gccgtgcaat acagtgataa cgccgccgcc aatttgttgc tgaaggagtt gggcggcccg
    19141 gccgggctga cggccttcat gcgctctatc ggcgatacca cgttccgtct ggaccgctgg
    19201 gagctggagc tgaactccgc catcccaggc gatgcgcgcg atacctcatc gccgcgcgcc
    19261 gtgacggaaa gcttacaaaa actgacactg ggctctgcac tggctgcgcc gcagcggcag
    19321 cagtttgttg attggctaaa gggaaacacg accggcaacc accgcatccg cgcggcggtg
    19381 ccggcagact gggcagtcgg agacaaaacc ggaacctgcg gagtgtatgg cacggcaaat
    19441 gactatgccg tcgtctggcc cactgggcgc gcacctattg tgttggccgt ctacacccgg
    19501 gcgcctaaca aggatgacaa gcacagcgag gccgtcatcg ccgctgcggc tagactcgcg
    19561 ctcgagggat tgggcgtcaa cgggcagtaa ggctctgaaa atcatctatt ggcccaccac
    19621 cgccgccctt gcgggcggca tggattacca accactgtca catttaggct aggagtctgc
    19681 gcggcagagc cgtgtgaccg gttttctgta gagcactgac gatggcggcg gcgctctctg
    19741 caattggcaa ggcgtcggcg ccaaggatac caatcttgcg gcgcgcggcg tgttatgacg
    19801 actggggtgc atttgagccg ccccatttaa ccttcgccct cacagatacg ccattcgcct
    19861 cagatttagc gccatgcaga cgagcttcca ctcggcttgc accttgtcca ggcccctcat
    19921 gctgaactga cgcaatccca tcaccgcctt gatccaacca ttcggagcct ccacgatcga
    19981 cttgcgccgg cggtaagctg catcgccttg ctccgttttc aatttcgccg caatcgccgc
    20041 cgtatgcgga tgggtcttgg cattgacctt ggcatcttca cgtccctcgc ggccgagggc
    20101 aacgatgaca tcgccgtggt gatcggcgac ctttgccaga acagcctcac tacggaatcc
    20161 cgcatccgcc agcgtctggg ccggcatttc tccggtgttg gcctgaactg ctgccagcat
    20221 gcccagcagc gcctgactgt ccgcggcgca gttggtcaac tccgccgcca cgatgatctg
    20281 gtgctcggca tcgaccgctg tgtacccgtt gtagctctgc tcggagccac caccggcgtg
    20341 tttcatgatc cggctgtccg gatcggtgaa gctttcctga tcacggtcat ccggcacacc
    20401 aaactcgcgt ttgtacgagc caccgccctt gtccgagcca tccggatggc gaggccggcg
    20461 gccatcgtct tcgctgcgcc cccgggcctg gtccgcttca cgctggcgcg cttccaggcg
    20521 cgcctttgcc gcctggatcg cctccaggcg cttctcgcgg cgagaaatct cggcaggaat
    20581 gtccagctcc ggctcgttac gctcctggtc gtcggtagcc ttggcgcgat caagcagcgc
    20641 cttgatctcg caatgcaatt cgtcctcggc cggcttcatg cgcttatagc tcatcgcctt
    20701 gtggcggctg gcgttggctt ttaccttggt gccgtcgacc gcgatcgtgc caagcttcac
    20761 cagcccacat tcgcgcgcca gttgcaccac ctgaacgaac aaattctcaa gctcggtcag
    20821 gtgtagggca cggaagtcac tcagcgtgcg gtgggccggg aagtttccag cggccagcac
    20881 acgcaacgcg acatcctcgt acagcttcct ggctagtttg cgcgaagaga agacgccgct
    20941 cgcgtaacca tagatcagca ctttgaccat catcgccgga tgaaacggct gattgcccgg
    21001 accaccgccg gcataccggg cgtggaatgc gctcaagtcc agcgtatcga cagtctcgct
    21061 gatgaagtag gcaagatgcc cttcaggtag ccactctccc agagaagggg gcagcagata
    21121 ggattggtcg ggtcggtaag gaaggtaact ggcagccatc cccgtatcgt cctcgatctt
    21181 ccgccgattt ggcttctgcc gcgcaggctc ctaggccacc gtagctaaac atacgagaaa
    21241 aaccgcttct tgagcgctct ctgagaccac cttgccgaca acgcagaaac ggttgcggaa
    21301 aaatcggcgt ttccggcgta cgccacccga cctggacgaa ctattgcgga cctggaactg
    21361 gagtagcgga attccccggg gtttcagcgt cgcgccacag cgcctcagat agatgcggta
    21421 gcctttggcg ggtcgtcatg ccgcggacca cccccccaaa aaattccaca atgcggaatg
    21481 gcggaatttt ctggggttcc cgcttacccc ccctgatccc aagactgaag atattaaggg
    21541 gttgggagag ttgaaagagg gtaaacctaa aacccctaaa caaggtggtg gtggtaagcg
    21601 ggcccgatgg tatggtgata aaaagcgtaa aatttatgaa tgggattccc agcacggtga
    21661 gcttgaaggg taccgcgcca gtgatggcga acacctcggg gcattcgatc caaaaacggg
    21721 taagcaggtt aaagggccgg atccaaaacg aaacattaaa aaatatcttt aagaggtaaa
    21781 tatggggctt aaattacata ttcattggtt tgataagaaa accgaagagt ttaaaggtgg
    21841 tgaatactca aaagacttcg gtgatgatgg ttctgtcatt gaaagtctgg ggatgccttt
    21901 aaaggataat attaataatg gttggtttga tgttgaaaaa tcatgggttt cgatattaca
    21961 gccacacttt aaaaatgtaa tcgatattag taaatttgat tactttgtat cctttgttta
    22021 ccgggatggt aactggtaag caaaagttat caaggatgat ttgaaataca gacttccggt
    22081 gttcagggat gaataccggg gtttttaaat acagggaagg tatatgaaaa aggtaaaggt
    22141 tgtttttctt tttatattga ttttttcagg ctttcttctg gtcgcatgtc aggcaaacta
    22201 tatccgggat gttcagggtg gaacggtggc accatcgtcc tcctctgaac tgacggggat
    22261 cgcggttcag tagaaaagat caaaggatct tcttgagatc ctttttttct gcgcgtaatc
    22321 ttttgccctg taaacgaaaa aaccacctgg ggaggtggtt tgatcgaagg ttaagtcagt
    22381 tggggaactg cttaaccgtg gtaactggct ttcgcagagc acagcaacca aatctgtcct
    22441 tccagtgtag ccggactttg gcgcacactt caagagcaac cgcgtgttta gctaaacaaa
    22501 tcctctgcga actcccagtt accaatggct gctgccagtg gcgttttgcg tgcttttccg
    22561 ggttggactc aagtgaacag ttaccggata aggcgcagca gtcgggctga acggggggtt
    22621 cttgcttaca gcccagcttg gagcgaacga cctacaccga gccgagatac cagagtgtga
    22681 gctatgagaa agcgccacac ttcccgcaag ggagaaaggc ggaacaggta tccgggaaac
    22741 ggcagggttg gaacaggaga gcgcaagagg gagcgattca tcggaaacgg tgatgatctt
    22801 taagtcctgt cgggtttcgc cactcctgac tgattcatgg ttgagccacc ggctcccaca
    22861 gatgcaccga aaaagcgtct gtttatgtga actcagtcag gagggcggag cctatggaaa
    22921 aacgccacct gcgtggcctt gccgttttgc ctcacatgtt agtcccctgc ttattcacgg
    22981 aatctgtggg taactttgca tgtgtccgca gcgcccgccg cagtctcacg gccggagcgt
    23041 agcgaccgag tgagcgagga ggcgcaattt ccccggcacc tacaagacgg acaccggacg
    23101 cgctgatgtg gcatattgtc ccctgattaa gtctttatat tccctgataa taaattacca
    23161 ggataggtga atcatatcgg tttttcgctg aacattttac gttaacctat ctctgttgct
    23221 tttttctcct tacggagaaa tacaggtcat ccccgcgagg gcgtggctga cctcaggggg
    23281 atatcccctg cttacgctgg ctggacgcca ccgacgcacg gtctctcccc ctctttctgg
    23341 ctccgtccgg ctggacgccg gccacgccag aaattcaccc ggcccccgtc aggctcacgc
    23401 ctgaccaccc acaaaaatcc acggtgctgg acgcacctgg cgaagcagca aagctgctcc
    23461 tgattttgcg ggtggtcagc cgctcgctat ggcgaactct gacgggggcc ggaacaccgg
    23521 aaaagaccgc actggggtgc cgccttttcc tctcacacgc tggggcgtgc tcgttgttcc
    23581 tccggggctg cgccttttcc gcatggggcg gaaagaggct ggcctccgtg gtgaaagctg
    23641 aacgcaatca ccacggacgt gaccgccgcc gccatgcctt ggggcatgtc cgcggcttgt
    23701 gcagcggggg ctgcacatca cgccggcaaa ccatcgtctg aaggagagag aac
//
