LOCUS       NZ_AP024408             7404 bp    DNA     circular CON 23-MAR-2024
DEFINITION  Aeromonas caviae strain KAM376 plasmid pKAM376_6, complete sequence.
ACCESSION   NZ_AP024408
VERSION     NZ_AP024408.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMD00270046
            Assembly: GCF_016861425.1
KEYWORDS    RefSeq.
SOURCE      Aeromonas caviae
  ORGANISM  Aeromonas caviae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Aeromonadales;
            Aeromonadaceae; Aeromonas.
REFERENCE   1
  AUTHORS   Suzuki,M., Maehana,S. and Kitasato,H.
  TITLE     Whole genome sequencing of carbapenem-resistant Aeromonas spp.
            isolated in Japan
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7404)
  AUTHORS   Suzuki,M., Maehana,S. and Kitasato,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-JAN-2021) Contact:Masato Suzuki National Institute of
            Infectious Diseases; 4-2-1 Aobacho, Higashimurayama, Tokyo 189-0002,
            Japan
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: Unicycler v. 0.4.8.0; Canu v. 1.8
            Genome Coverage                   :: 132x
            Sequencing Technology             :: Illumina MiniSeq; ONT MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_016861425.1-RS_2024_03_23
            Annotation Date                   :: 03/23/2024 02:24:53
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,704
            CDSs (total)                      :: 4,544
            Genes (coding)                    :: 4,441
            CDSs (with protein)               :: 4,441
            Genes (RNA)                       :: 160
            rRNAs                             :: 11, 10, 10 (5S, 16S, 23S)
            complete rRNAs                    :: 11, 10, 10 (5S, 16S, 23S)
            tRNAs                             :: 120
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 103
            CDSs (without protein)            :: 103
            Pseudo Genes (ambiguous residues) :: 0 of 103
            Pseudo Genes (frameshifted)       :: 39 of 103
            Pseudo Genes (incomplete)         :: 64 of 103
            Pseudo Genes (internal stop)      :: 15 of 103
            Pseudo Genes (multiple problems)  :: 13 of 103
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AP024408.1.
            Annotated at DFAST https://dfast.nig.ac.jp/
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..7404
                     /organism="Aeromonas caviae"
                     /mol_type="genomic DNA"
                     /strain="KAM376"
                     /db_xref="taxon:648"
                     /plasmid="pKAM376_6"
                     /geo_loc_name="Japan:Kanagawa"
                     /collection_date="2019"
     gene            1..1011
                     /locus_tag="JSX26_RS23385"
                     /old_locus_tag="KAM376_45650"
     CDS             1..1011
                     /locus_tag="JSX26_RS23385"
                     /old_locus_tag="KAM376_45650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005321767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_128318464.1"
                     /translation="MVKQAIQADEFVERLPLRPYCTDDPAQGLHIRPQATALAFRHIQH
                     NPPPHVSCIVFDVDRKPYEQRREGYQEWRERGLPAPHWIAINPENGNYHLGYLLAAPVA
                     RTNAARLKPLRYLAAIEHVLAKKLGADMGYVGLITKNPVHSDWWTIWHNHVPYSLDYLA
                     EFCPDADLAAYNRRSGKEASGLGRNVTVFDNVREWGYCAVREYWRPNGYEAWAEAVRAA
                     CESANAFGREQGGPLPHSEIKATAKSIARWIWRHLTPTSFADYVDRTHTTEIQARRGAK
                     GGKVSKGGGRPSKAADLLPAVLELKAQGYSNRDIAEDLGIGSASVSRYLSKISPE"
                     /name="replication initiation protein"
     gene            complement(1163..1453)
                     /locus_tag="JSX26_RS23390"
                     /old_locus_tag="KAM376_45660"
     CDS             complement(1163..1453)
                     /locus_tag="JSX26_RS23390"
                     /old_locus_tag="KAM376_45660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005321770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_128318465.1"
                     /translation="MKDNADKGTGDMFGIKRGRGRPKTGSAKTGAERQAAYRAKQQENN
                     VTVTINRGLLEGLDAQMQAIRDGGSAVVLTSEQAGEILRALRTAENKQLRG"
                     /name="hypothetical protein"
     gene            1651..1989
                     /locus_tag="JSX26_RS23395"
                     /old_locus_tag="KAM376_45670"
     CDS             1651..1989
                     /locus_tag="JSX26_RS23395"
                     /old_locus_tag="KAM376_45670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006714101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="WP_128318466.1"
                     /translation="MPTEQPKRLKTIKVRVTETEWASLRAACPKAQLAEWMREHCLGVV
                     PQQRRTPPPTIDPALLRQVAGIGNNLNQIARRINASPLTTLDKVEYLAALAAVARELEG
                     LRSDRQNP"
                     /name="MobC family plasmid mobilization relaxosome protein"
     gene            2189..>2623
                     /locus_tag="JSX26_RS23400"
                     /pseudo=""
     CDS             2189..>2623
                     /locus_tag="JSX26_RS23400"
                     /inference="COORDINATES: protein motif:HMM:NF015397.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /name="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            2676..3095
                     /locus_tag="JSX26_RS23405"
                     /old_locus_tag="KAM376_45680"
     CDS             2676..3095
                     /locus_tag="JSX26_RS23405"
                     /old_locus_tag="KAM376_45680"
                     /inference="COORDINATES: protein motif:HMM:NF016710.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeB family mobilization protein"
                     /protein_id="WP_234932339.1"
                     /translation="MAKTFEQTSKQQADDIESSLKPEFEKHEKAIKKALDSSRQSISDA
                     IQDQQKRIGWLLLKSWGVMLISALLLLVATSGTLWYQGNLIAERQATLEELAKKGGKLI
                     LSDRCKDENGKHRFCIRMNVDEGKFGDDYMIPKGY"
                     /name="MbeB family mobilization protein"
     gene            3099..3332
                     /locus_tag="JSX26_RS23410"
                     /old_locus_tag="KAM376_45690"
     CDS             3099..3332
                     /locus_tag="JSX26_RS23410"
                     /old_locus_tag="KAM376_45690"
                     /inference="COORDINATES: protein motif:HMM:NF016769.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeD/MobD family mobilization/exclusion protein"
                     /protein_id="WP_113740815.1"
                     /translation="MTELERHLLNALETLQSEQEQQWRSLQTACDSLLGLYETTKKENA
                     SLQGEVRALRQQCEHLSKQVSSLATQVASLKA"
                     /name="MbeD/MobD family mobilization/exclusion protein"
     gene            3661..5559
                     /locus_tag="JSX26_RS23415"
                     /old_locus_tag="KAM376_45710"
     CDS             3661..5559
                     /locus_tag="JSX26_RS23415"
                     /old_locus_tag="KAM376_45710"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: protein motif:HMM:TIGR00254.1"
                     /GO_function="GO:0009975 - cyclase activity [Evidence IEA]"
                     /GO_process="GO:0009966 - regulation of signal transduction
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="WP_202979086.1"
                     /translation="MHKRKFTTLAFYSLALVLLLGLGLGLHQYYIYKVTRETHKTTVDR
                     NLSLMHMRADGYLERLALDGEFIASTPILRMYLENPSAETLAGAQDALRTLASLRPYLD
                     QLRYIDQQGMERIRVNQRGGPPQLATELQNKSDRDYVQRGLALTAGGVYFSPIDLNIEH
                     GQIERPFRPILRSVAKVMVNGSPAGMVVQNANVDELEKRLRTELPTAVAQPVVLNSSGG
                     WIMGGGEKDWLFSAKPDAPDALLSTQEPALWEKIQASSSGQFEYRGECHYYAWYQFKQQ
                     QWQAERWLVAQRSAGQACGHLTASAVKTWATQLVVMSTFTVPLLVLWLLSRWNARELRR
                     GLRETNSQLELITSEADVALLMVDHECRVCWINPESERLLGWKTDELVGANLHERTHIR
                     NGEDLHSGPCPTLQALQTGQRYRNDRDRVLAKSGEILNVSMRVSPFGEGEARNAIVTIA
                     DVGDAVDREQRLTRLATTDPLTGALNRRSIMERLQDMVEHQKMPPCVLMGDIDFFKKVN
                     DTYGHAAGDEVLKTFTNTIRQLLRKGDFLGRLGGEEFVVALENTELPNAQTMAERLRLA
                     IANSQTPNDGGIPIAITASFGLALYSRDESVDAWLARADAALYRAKQSGRNRVEIA"
                     /name="diguanylate cyclase"
     gene            complement(6019..6447)
                     /locus_tag="JSX26_RS23420"
                     /old_locus_tag="KAM376_45720"
     CDS             complement(6019..6447)
                     /locus_tag="JSX26_RS23420"
                     /old_locus_tag="KAM376_45720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017413093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ProQ/FINO family protein"
                     /protein_id="WP_128318468.1"
                     /translation="MHNTKPRTVLSLKKAPPQPEITQAAQQSTAIPTKRKIPAAFPCLQ
                     SHWPELFNLKHPTPLKIGILAPVIASLKQQDEPYTDTQIGKAIGWYCRRFEYLKALTNA
                     PHRMGIDGNTFPISDQDRQNAMKQIKARIKEARSCPKR"
                     /name="ProQ/FINO family protein"
     gene            6588..6839
                     /locus_tag="JSX26_RS23425"
                     /old_locus_tag="KAM376_45730"
     CDS             6588..6839
                     /locus_tag="JSX26_RS23425"
                     /old_locus_tag="KAM376_45730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007423962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4160 domain-containing protein"
                     /protein_id="WP_128318469.1"
                     /translation="MPTVLIIGGWRVVIYPNDHRPAHVHVIGGGCEAVFNLSGDQGGPE
                     LRENYGFDSKALKRIWAELQGNQAHLISQWEVIHGTNR"
                     /name="DUF4160 domain-containing protein"
     gene            6823..7245
                     /locus_tag="JSX26_RS23430"
                     /old_locus_tag="KAM376_45740"
     CDS             6823..7245
                     /locus_tag="JSX26_RS23430"
                     /old_locus_tag="KAM376_45740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014005992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2442 domain-containing protein"
                     /protein_id="WP_128318470.1"
                     /translation="MELTDEMIAQANKRGSEARKRSPVATSVRYDRRIGRVVIALSSGL
                     ELAFAPHLAQGLEAAKPSDLQEIEISPSGLGVHFPRLDADLYLPSLLEGLLGSENWAAS
                     KMGAKGGKAKTPAKVAAARANGAKGGRPRKNVPAAA"
                     /name="DUF2442 domain-containing protein"
     Typing          2..954
                     /name="rep_cluster_1010"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="93.187"
                     /coverage="95.0"
                     /evalue="0.0"
     Typing          2511..3526
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="97.64"
                     /coverage="99.0"
                     /evalue="0.0"
ORIGIN
        1 atggtaaaac aagcgattca agccgacgaa ttcgtcgaac ggctccccct ccgcccctac
       61 tgcaccgacg atccggcgca gggtctgcat atccgcccgc aggcaactgc gctggccttc
      121 cgtcacattc agcacaaccc accgccgcat gtctcctgca ttgtgtttga tgtggacaga
      181 aagccctatg agcagcggcg agaagggtat caagagtggc gagagcgtgg cttgcctgcg
      241 ccgcattgga tcgcgatcaa ccccgaaaat ggcaattacc accttggcta tctgctggcc
      301 gcgccagtgg cgcgtaccaa tgcagccagg ttaaagccac tgcgctatct agcggctata
      361 gagcacgtgc tggcgaagaa gctgggcgct gacatggggt atgttgggtt gatcaccaaa
      421 aaccccgtac acagcgattg gtggacgata tggcataacc atgtgcccta ttccctcgac
      481 tatctcgcgg agttctgccc agatgctgat ttagcggcct acaaccgccg tagcggtaaa
      541 gaggcgagcg ggctggggcg taacgtcaca gtgttcgata acgtgcggga atggggctac
      601 tgcgcggtgc gggagtattg gcggcccaat ggctatgaag catgggctga ggctgtccgt
      661 gccgcttgtg agagcgctaa tgcgtttgga cgcgagcaag gtggcccgtt gccccatagt
      721 gagatcaagg ccactgccaa gagcatcgcc cgttggatct ggcggcacct taccccgacc
      781 tcgtttgcgg attacgttga tcggacacat accaccgaga tccaagcgcg gagaggggct
      841 aagggcggca aggtatccaa gggcgggggg agaccgagca aggccgctga tcttctgcct
      901 gcggtgttag aactcaaggc gcagggctac agtaaccgcg acattgccga ggatttaggg
      961 atcggttcgg caagtgttag ccgctatctc tccaaaatct cgccagagtg atccaaaaca
     1021 agcctatatc agataacagc gcccgaaggg cgcttcttgt ctctagagaa tcattcaaga
     1081 gagaggatct tggcgagggg ggtaacggcg atcccgtagg gctgtccatc aggccatgtg
     1141 ttcggcctgt gggcagtagc tgttatcccc ggagctgttt gttctctgct gttcgtagcg
     1201 cccgcaagat ctccccggcc tgttccgagg tcagtaccac cgctgaaccc ccgtctctga
     1261 tcgcctgcat ctgggcatcc agtccttcca atagccctct atttatcgtc acagtaacgt
     1321 tattttcctg ctgttttgcc cggtaggcag cttgtcgttc tgcccctgtt ttggctgatc
     1381 cggttttggg tctaccccgt ccgcgcttga tgccaaacat gtctccggtt cccttatctg
     1441 cgttgtcttt catcgtccaa attcccgtca cagtgaccat aaatattatt tgtcactgtg
     1501 acacaaaaag cattcatccg caccctcaaa attcaaccca tgttaaagtc ataagcaagg
     1561 acacacaggg ggcccgcttc gcggtctatc ccctgtggcc ttgttcaggg ggcaagcccc
     1621 ccgaaacccc cgaaaaaacg gaggcaactg atgccgacag agcagccaaa acggctcaag
     1681 actatcaagg tcagagtcac cgaaaccgag tgggccagct tgcgggcggc ctgccccaaa
     1741 gcccagttgg cggagtggat gcgcgagcac tgcttggggg ttgttcccca gcagcggcgc
     1801 accccaccgc caaccatcga tccggcattg ctccggcagg tggccgggat cggtaacaac
     1861 ctcaaccaga tcgcccggcg catcaatgcc agcccgctga ccacattgga caaggtggaa
     1921 taccttgctg cgttagccgc cgtggcccga gaactggagg ggctacgcag tgatcgtcaa
     1981 aatccatagc cggggagtcg gtcgcggatc tggtccggtg gaatacctgc ttggcaaaga
     2041 cgggaaccgg gacggggcca cgctggatcg cggcgacccc gagatggtca aggagttgat
     2101 agacggcagc cattacgccc agcggtacac cagcggcgtg ttgtcgttcc acgaaccgga
     2161 cttgccgagg gagaccaaag agcggttgat ggacgagttc gagcaagccc tgttgcccgg
     2221 actggacgcc gatcagtatg cggtgctgtg ggtcgagcac cgggacaaag accgcctaga
     2281 gctgaatttc gtggtgccga acgtcgaact gttgtccggc aaacgccttc agccgtattt
     2341 ccacggggcg gacggccacc ggatcaacgc atggagaacg gccatcaatg gcgagttggg
     2401 attgcacgac ccggacgacc cgatcaatcg gcaggccgta accacggcca aagatctccc
     2461 ccggaacaag ctggaagccg aacaagccat tacaggcggc ttgttgggca tggctgcggc
     2521 ggggctcgtc aaaaaccggg aggacgttct caagaccctg accggggcgg ggttcgacgt
     2581 taccaggaca accaagaaca gcatcagcat tgccgacccc gaagggggcc ggaatatccg
     2641 cctaaagggg gcgatctatg agcaagattt tagacatggc aaagaccttc gagcagacat
     2701 cgaagcagca agccgacgat atagagagca gtctgaagcc cgagttcgag aagcacgaga
     2761 aagctatcaa aaaggcgttg gactcaagca ggcagagcat cagcgacgcc atccaagacc
     2821 agcagaagcg gatcggctgg ctcctgctca agagctgggg agtgatgctg atctcggcct
     2881 tactgttgct ggtcgcgacg agcgggacgc tgtggtatca ggggaacctg atcgccgagc
     2941 ggcaggccac cctagaggag ttagccaaga agggggggaa attgatcctc agcgacaggt
     3001 gcaaggacga gaacgggaag caccggtttt gcatcaggat gaacgtggac gaagggaagt
     3061 tcggggacga ctacatgata ccaaagggct actaaacgat gaccgagcta gaacggcact
     3121 tattgaacgc gctagagacc ttgcagagcg agcaagagca gcaatggcgc agcttgcaaa
     3181 cagcgtgcga cagcttgctg gggctgtacg agacgacgaa aaaagaaaac gcgagtttgc
     3241 agggagaagt gagagccttg cgccagcagt gcgagcactt gagcaagcag gtcagcagct
     3301 tggcaacgca ggtcgccagc ttgaaggcgt gatcgcgcag cagacggcgc agacgcagga
     3361 aggtttgttg gacgaatacc agcaggccca cgcagagcgg aacctgtatt tcaatcggaa
     3421 gcatgagcag aaagagatct ccggcttgcc gatagacaag gccagagagt acctacagga
     3481 aggactggag gggcggatag agcggcagca ggcccgcgat tcgggattgg aaggccgcgc
     3541 tgaaccgatt taccattgag ttcggagacc gtatctgcgt caattgaagt ccgaaccgtt
     3601 tacacaaaaa ttcggacacg ccctgtgtga gtcctcaaaa tctccggaaa gacaacgttc
     3661 atgcacaaac gaaaatttac cactctcgcc ttctattcgt tagcgttggt gcttttgctg
     3721 ggactgggtc tcggcttgca ccagtactac atctacaagg tcactcgtga gacgcataaa
     3781 accacggttg atcgcaatct gtcgttgatg catatgcggg ctgacggcta tctggaacgg
     3841 ttggcactgg atggagaatt cattgcgagc acccccatcc tgcgcatgta tcttgaaaac
     3901 ccctcggcag aaacactggc gggcgcgcag gacgctctcc ggactcttgc ttcgctgcgt
     3961 ccctatctgg atcaactgcg ctacatcgat cagcagggca tggagcggat tcgggtgaat
     4021 caacgaggtg ggcctcctca attggccaca gagctacaaa acaaatctga ccgtgattac
     4081 gttcagagag gcttggcact cacggctggc ggcgtctatt tctcgccaat tgatctgaac
     4141 attgaacacg gacagatcga gcgccccttc cgccccatac tgcgttcggt ggccaaggtc
     4201 atggtcaacg gcagccctgc gggcatggtg gtgcagaatg ccaatgtgga tgaactggaa
     4261 aaacggttgc gcacggaact gccaacggcg gtggcgcaac cggtggtgct caacagcagc
     4321 ggcggctgga tcatgggcgg tggtgagaag gactggctgt tttcggcaaa gcctgatgcc
     4381 ccggacgctc tgctatccac acaagagccc gcgctgtggg aaaaaatcca ggccagttcg
     4441 tcaggtcaat ttgagtatcg tggggaatgc cactattacg cttggtacca attcaagcag
     4501 cagcaatggc aggcagagcg ctggctggta gctcagcgct ctgccggtca agcctgcgga
     4561 cacttgaccg cttcggcagt taagacgtgg gccacgcaac tggtggtaat gtcgactttc
     4621 accgttccgc tgttggtgtt gtggctgttg tcccgctgga acgcgcgcga actacggcgt
     4681 ggacttagag agacgaactc ccagctagaa ctcatcacta gcgaagctga cgttgccctg
     4741 ttgatggtcg accatgagtg ccgcgtctgc tggattaacc ctgaatccga acgcctattg
     4801 ggctggaaga ccgacgagtt ggttggtgca aacttgcatg aaagaaccca catacggaac
     4861 ggggaggatc tgcactccgg gccctgtccg acgctgcagg cgcttcaaac aggacagcgt
     4921 taccgcaatg atcgtgaccg agtgctcgcg aagtctggcg aaattttgaa tgtaagcatg
     4981 cgtgtgagtc cgtttggtga gggtgaagcg cgcaatgcca tcgtgacgat tgccgacgta
     5041 ggggacgcag tggaccgaga gcagcgtttg acacggcttg ccacgactga tccattgacc
     5101 ggcgcactca accgtcgatc catcatggag cgtctgcaag acatggtcga acaccaaaag
     5161 atgccacctt gcgtgttgat gggcgatatc gattttttca agaaagtcaa cgacacctat
     5221 ggacacgctg cgggcgatga ggtactcaaa actttcacca acacgatacg tcagttgctg
     5281 cgcaagggtg actttttagg tcggctcggc ggtgaagagt tcgtggtggc cttggagaac
     5341 accgagctgc caaacgccca aaccatggcc gaacgcctgc gcctagccat tgcaaatagc
     5401 caaaccccaa acgatggcgg tattcccatc gcaatcaccg ccagctttgg cttggcgctg
     5461 tacagccgtg acgaatcggt ggatgcgtgg ctggcccgcg cagatgctgc actgtaccgc
     5521 gccaaacaat cggggcgaaa ccgggtggaa atagcttagc gctgctgggg tgctgtttcg
     5581 caggatgccc tgcagacgca gatcacgccc attcggccgg aaatcctcgc gcctatcgca
     5641 tccgacggaa atctacctgc tcgcattcat tgcgattgcg tttccacaca gcctcggtcg
     5701 ggtgccgtcg cgtgcgcagt gtcaaagctg acatgacgaa tacgtgagaa gggctgatgc
     5761 tcgccgtccg gtcaagctgt tgagtcgccc cgggttctac cctgttttca cggacacatc
     5821 taaaagaggc ataatgtgcc tgtaaggagt gttcatgacc aagcgaagaa aattcagtcc
     5881 agagttcaag cgagaagctg tcaaactgac ccagcagccg ggaacggggg cggggctttg
     5941 agatgtagct gccgcgctgc gcttgccgac tcccaaacga agcgcgacag actgcgctag
     6001 tcgctcttgt ttgggagttc atcgtttggg gcaggatcta gcctctttga tgcgcgcctt
     6061 gatttgtttc atcgcgtttt ggcggtcttg gtcgctgatg gggaatgtgt tgccatcaat
     6121 ccccattcga tgaggagcat tggtgagggc tttgaggtac tcaaatctac ggcaatacca
     6181 gccaatggcc ttcccaatct gagtatcggt gtaaggctcg tcctgttgct tcaggctggc
     6241 gatgacagga gctaggattc cgattttaag tggagtggga tgtttgaggt tgaatagctc
     6301 gggccagtgc gattgtaggc aagggaaagc cgctgggatt tttctcttcg taggtatcgc
     6361 ggtggactgt tgtgctgctt gggttatctc aggctgtggt ggggcctttt taagactcag
     6421 tactgtacgg ggcttggtgt tgtgcatgga cgtatacctg cggaaatgat gtttgcaggc
     6481 aagttatcga aacccccatc aggatgcaaa aacagttgaa ctatcgataa tgcacccatt
     6541 cgagtgtatt attgcgttta tagaaaccaa aacagttagg ttgtttgatg ccaacggtgt
     6601 tgatcattgg tggctggcga gtggtgattt atccaaacga ccatcgtccg gcgcacgtac
     6661 acgtgattgg gggcggctgc gaggcggtgt ttaatctctc gggtgatcaa ggcgggcctg
     6721 agctgcggga aaactacgga tttgatagta aagcgctgaa acggatctgg gcagagttgc
     6781 aaggcaatca agctcacctg ataagccaat gggaggtgat ccatggaact aaccgatgaa
     6841 atgatcgcac aagcaaataa acgcggttct gaagcgcgta agcgtagtcc tgttgctacg
     6901 agcgtgcgtt atgaccggag gattggacgg gtcgttatcg ccttgtcttc tggtttggaa
     6961 ctggcctttg cccctcatct ggcacagggg ttggaggccg cgaagcctag cgacttacag
     7021 gagatcgaga tctctccgtc agggttggga gtgcactttc cgaggttgga tgcagatctc
     7081 tacttacctt ccctgctgga agggttgttg ggctctgaga actgggcggc atccaagatg
     7141 ggggcgaagg gcggcaaggc aaaaaccccc gctaaagtcg cagcggcgcg ggccaacggc
     7201 gctaaaggtg ggcgtccaag aaaaaacgtg cctgcggcgg cctgagtgcg gtaacgtact
     7261 gcctagaaaa gacaaacccc gaatctctgt tcatcgactt ggcggaagag cacagagagt
     7321 tcggggccgt tcacgaagaa cagagaaagc atatcacatg actgacctca cacaagactg
     7381 caccgccaat aagcgcggtg acgg
//
