LOCUS       NZ_AP024316            20731 bp    DNA     circular CON 23-SEP-2023
DEFINITION  Staphylococcus aureus strain BDH17 plasmid pBDH17-1, complete
            sequence.
ACCESSION   NZ_AP024316
VERSION     NZ_AP024316.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMD00269944
            Assembly: GCF_019669345.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1
  AUTHORS   Nakaminami,H., Kim,E.S., Kaneko,H., Yokomori,S., Moon,S.M.,
            Song,K.H., Jung,J., Park,J.S. and Kim,H.B.
  TITLE     Comparative genomics analysis for a human variant of CC398 (ST1232)
            methicillin-resistant Staphylococcus aureus isolated in Korea and
            Japan
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 20731)
  AUTHORS   Kaneko,H. and Nakaminami,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JAN-2021) Contact:Hiroshi Kaneko Tokyo University of
            Pharmacy and Life Sciences, Department of Microbiology; Horinouchi
            1432-1, Hachioji, Tokyo 192-0392, Japan URL
            :https://www.toyaku.ac.jp/
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.7
            Genome Coverage                   :: 1932x
            Sequencing Technology             :: MGI DNBSEQ; ONT GridION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 09/23/2023 03:29:38
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,784
            CDSs (total)                      :: 2,702
            Genes (coding)                    :: 2,618
            CDSs (with protein)               :: 2,618
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 42 of 84
            Pseudo Genes (incomplete)         :: 38 of 84
            Pseudo Genes (internal stop)      :: 26 of 84
            Pseudo Genes (multiple problems)  :: 18 of 84
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AP024316.1.
            Annotated at DFAST https://dfast.nig.ac.jp/
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..20731
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="BDH17"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="pBDH17-1"
                     /geo_loc_name="South Korea"
                     /collection_date="2019"
                     /genotype="ST1232"
     gene            166..842
                     /locus_tag="K5602_RS13675"
                     /pseudo=""
     CDS             166..842
                     /locus_tag="K5602_RS13675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /name="replication initiator protein A"
     gene            <853..1135
                     /locus_tag="K5602_RS13935"
                     /pseudo=""
     CDS             <853..1135
                     /locus_tag="K5602_RS13935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199895.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            2347..2964
                     /gene="cadD"
                     /locus_tag="K5602_RS13680"
                     /old_locus_tag="BDH17TP_25970"
     ARG             2348..2961
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="99.51"
                     /coverage="100.0"
     gene            2983..3330
                     /locus_tag="K5602_RS13685"
                     /old_locus_tag="BDH17TP_25980"
     CDS             2983..3330
                     /locus_tag="K5602_RS13685"
                     /old_locus_tag="BDH17TP_25980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119691.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNQEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            3499..3591
                     /locus_tag="K5602_RS13690"
     CDS             3499..3591
                     /locus_tag="K5602_RS13690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            3803..4777
                     /locus_tag="K5602_RS13695"
                     /old_locus_tag="BDH17TP_25990"
     CDS             3803..4777
                     /locus_tag="K5602_RS13695"
                     /old_locus_tag="BDH17TP_25990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="WP_000072391.1"
                     /translation="MSNTKIKYQIFISSTYLDLIEERQAVVEAVLNSNNIPAGMELFNS
                     SSKSQWEIITQWINESDAVILLLGSSYGTIDSEENISYTEMEYNFAKSLGKPIYVFEMN
                     KASTESAEKSKKLDEFKTKVKENRLISPNINDISELKSKVSQTLMQSVPSEIKENSGWI
                     RVQDCGKNVKKLKKLDAIQRDLDTYDFLKEELYKIFMYVKTFYFQHTPFDDSYIEDIEN
                     YLLNYENNPHKSFMKIKVYDYKNFLKHLKNILILIKQGKKPLAQAGHFKLSFYEEDLKL
                     LQKNYKTTLVDIKGLNKHFYKECDRCLKAYNIFIEGINKHLYE"
                     /name="DUF4062 domain-containing protein"
     gene            complement(4897..5712)
                     /locus_tag="K5602_RS13700"
                     /old_locus_tag="BDH17TP_26000"
     CDS             complement(4897..5712)
                     /locus_tag="K5602_RS13700"
                     /old_locus_tag="BDH17TP_26000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019467708.1"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="WP_000164958.1"
                     /translation="MTKNQNFIETKEYKRFAEFCDACIKYQYIGICYGQPGVGKTLSSR
                     YYTNWDTIEKQVNHRGWEDLASKTTDDILSVDKIFYNAPAEKQTKLRNDLYSITAIIDL
                     GQKLHVVNKYGHEHSKHYSDMFKYIDLIIVDEIDRLKVQHLEQLRAIYDEHNLAMIFIG
                     MPGIEKKLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWQDLGFDLKLEDFTDYEAIT
                     TIIKITKGNFRLIHRLFAQIDRIMDINGLDKISTEVVETARDSLVIGIR"
                     /name="AAA family ATPase"
     gene            complement(5705..7148)
                     /locus_tag="K5602_RS13705"
                     /pseudo=""
     CDS             complement(5705..7148)
                     /locus_tag="K5602_RS13705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790716.1"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /name="DDE-type integrase/transposase/recombinase"
     gene            complement(7120..7713)
                     /locus_tag="K5602_RS13710"
                     /old_locus_tag="BDH17TP_26030"
     CDS             complement(7120..7713)
                     /locus_tag="K5602_RS13710"
                     /old_locus_tag="BDH17TP_26030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690636.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690638.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNQKDLNLLKTLYDNGTPI
                     KTIAEQWHVSRTTIYRYLNKLEDKEDEKQGEVSN"
                     /name="recombinase family protein"
     gene            complement(7977..8357)
                     /gene="blaI"
                     /locus_tag="K5602_RS13715"
                     /old_locus_tag="BDH17TP_26040"
     ARG             complement(7981..8357)
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="99.21"
                     /coverage="100.0"
     gene            complement(8347..10104)
                     /gene="blaR1"
                     /locus_tag="K5602_RS13720"
                     /old_locus_tag="BDH17TP_26050"
     ARG             complement(8351..10104)
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.56"
                     /coverage="100.0"
     gene            10211..11056
                     /gene="blaZ"
                     /locus_tag="K5602_RS13725"
                     /old_locus_tag="BDH17TP_26060"
     ARG             10212..11053
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            11425..12033
                     /locus_tag="K5602_RS13730"
                     /old_locus_tag="BDH17TP_26070"
     CDS             11425..12033
                     /locus_tag="K5602_RS13730"
                     /old_locus_tag="BDH17TP_26070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002436987.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_001566953.1"
                     /translation="MIVGYARVSSNDQNLERQLENLKTFCAEKIFTEKQSGKSIENRPV
                     LQEALNFLRMGDRFVVESIDCLGRNYDEVIHTVNYLKDKEVQLMITSLPMMNEVVGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRI
                     IYHRVVEMLEEGQSISKIAKEVNITRQTIYRIKNDNDLI"
                     /name="recombinase family protein"
     gene            12447..12740
                     /locus_tag="K5602_RS13735"
                     /old_locus_tag="BDH17TP_26080"
     CDS             12447..12740
                     /locus_tag="K5602_RS13735"
                     /old_locus_tag="BDH17TP_26080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="WP_000726502.1"
                     /translation="MKKKFVSSCIASTILFGTLLGVTYKAEAATVHVAGGVWSHGIGKH
                     YVWSYYSHNKRNHGSTAVGKYSSFSGVARPGVQSKASAPKAWGGNKTFYSLH"
                     /name="lactococcin 972 family bacteriocin"
     gene            12815..14749
                     /locus_tag="K5602_RS13740"
                     /old_locus_tag="BDH17TP_26090"
     CDS             12815..14749
                     /locus_tag="K5602_RS13740"
                     /old_locus_tag="BDH17TP_26090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001670421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="WP_000713729.1"
                     /translation="MKKFKLFLDFSTLLLISGLLFLFFFKENEEIIPESSNILTISNWD
                     KSNSKSKVLDVIESGAKNQNIQIIKSVKDFDNKKEFFVFNSKRNNSDFIRNKTSLLTPS
                     DLLNREIKGKYYIIGEHFNVEELTSELKKAGLTSEVEYINRNILFFELVIDNDLLVPFI
                     FLGVLYLLYFLYDRGYNLKFYAIQKLHGFSTTRIIFHNIHIKIIYWLVLTAIFFIANIL
                     IIHIANLELDFLMFIRRFIVLLFVFACITTLLWLISYSLLLKLSIPLILKGKKGYKFSI
                     FMGTFTKCIMVLILSFLLAQNLNAYTKLKNIYDSEKIWQKLDNYYTLEISPNIRNSEEK
                     QILETNIYNLIKKSEQLGGLLLKNNNIANPDKNNYIPENGNVFFINNNFLNFYKNINHD
                     FKMIDNHSDKINVFIPPRLQYQKSEIQKNHQGWIDFQKQQNKKVDVQVLSKNVSVFSFD
                     RTTNLKFGYLDSPIVMLLTLDDLTGDFYLAAVSQGGYLFKDLDTLKQLLKDNHLEEEIS
                     GITNYKDSVLNELNETKTKMIITIVTIIINVFILLIATVFETIQYFSWNKKQLLLRKIH
                     GYSLFSSNVRYLTISILLSIMLAYTTHILFGSKILLFIIMSIAIIQHLLQIAYIKYLEK
                     YFKDLMREI"
                     /name="bacteriocin-associated integral membrane family
                     protein"
     gene            14753..15064
                     /locus_tag="K5602_RS13745"
                     /old_locus_tag="BDH17TP_26100"
     CDS             14753..15064
                     /locus_tag="K5602_RS13745"
                     /old_locus_tag="BDH17TP_26100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="WP_000831610.1"
                     /translation="MKRTLIIVTIVLLIIILSLLLVRNEHLDRFNPLLKEKVSYAKVPK
                     DTQDYRNITVYSKNGEKKSYKLDFLGYDPTKEYVKVNHKGKYVRSIEYITKDIPSFLK"
                     /name="YxeA family protein"
     gene            15076..15702
                     /locus_tag="K5602_RS13750"
                     /old_locus_tag="BDH17TP_26110"
     CDS             15076..15702
                     /locus_tag="K5602_RS13750"
                     /old_locus_tag="BDH17TP_26110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000593103.1"
                     /translation="MIKLENVFVKKGNKNILDGCNFNFEKGKSYALVGESGAGKSTLLN
                     IIAGFEDVSQGSIYIEDKLLKKKVDFYRYTLGYLFQNFALLENQTISQNLDLALKFKKN
                     KKDNMNLKKEVLKKVGLDLDIKRIVSSLSGGEQQRVALARLILKDPKIILADEPTGSLD
                     TKNGKIVIDLLLKLLDENKTMIVVTHDLELAKRFDVIVNISELRS"
                     /name="ABC transporter ATP-binding protein"
     gene            15940..16569
                     /gene="mobV"
                     /locus_tag="K5602_RS13940"
                     /pseudo=""
     CDS             15940..16569
                     /gene="mobV"
                     /locus_tag="K5602_RS13940"
                     /inference="COORDINATES: protein motif:HMM:NF013258.3"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /name="mobV"
     gene            16663..17208
                     /locus_tag="K5602_RS13765"
                     /old_locus_tag="BDH17TP_26140"
     CDS             16663..17208
                     /locus_tag="K5602_RS13765"
                     /old_locus_tag="BDH17TP_26140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001805533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000273005.1"
                     /translation="MYEIKTKNVGGWFHKEKQETGNIVITKTDFEKYTKQIKAAQMILD
                     DYECIKSGKSLKKAEKQNESLVNELTSVHMENEKLVEEFNDLAQRYNYLLSENEKKDKE
                     LNYTLKLFNQVFKIIKSMMKEERYHTLINHIDNHLDNSKIREVMTIDNNDEQFFKKKYQ
                     AQEREIIFKEDREDGYTL"
                     /name="hypothetical protein"
     gene            17592..18452
                     /locus_tag="K5602_RS13770"
                     /old_locus_tag="BDH17TP_26150"
     CDS             17592..18452
                     /locus_tag="K5602_RS13770"
                     /old_locus_tag="BDH17TP_26150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000145511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_000145511.1"
                     /translation="MTGETVVYKNEMNLVPLRRFTATEINLFFAMCNKLKEQDTNTLRL
                     SFDELKKLSNYSPETRNINRFANDLDNVYKKMLNLTIRYEDDDVIERFVLFNHYRIHKR
                     EQYLEISTSSNLKHILNSITNNFTKFELKEMTRLKSTYSKNMFRLLKQYKHTGYLKIHI
                     DDFKNRLDIPKSYRMTDINKNVFKPIIIELGSIFNNLTINKIKAKKGRKIEWIEFTFDA
                     EKRIHNKRQPQMSKIDKSRQYVRREKTPKWLEERSYEKQPQKDYDPQLEKEREDFLKQL
                     ELNWE"
                     /name="replication initiation protein"
     gene            18539..18880
                     /locus_tag="K5602_RS13775"
                     /old_locus_tag="BDH17TP_26160"
     CDS             18539..18880
                     /locus_tag="K5602_RS13775"
                     /old_locus_tag="BDH17TP_26160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761340.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000761341.1"
                     /translation="MKLAEAIKEQRELKGWSQEELANILKVSRQSVSKWESAKNYPSLD
                     ILIAMSDLFGISLEHLIKGDARFKKVILEGNYRESNRVPSIVDFLYDFWWLFFPVAGFL
                     VWAIHSFMG"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(19119..19190)
                     /locus_tag="K5602_RS13780"
     CDS             complement(19119..19190)
                     /locus_tag="K5602_RS13780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_106873653.1"
                     /translation="MNEILVHIMTTAISGCLVTLFGY"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            19339..19524
                     /locus_tag="K5602_RS13785"
                     /old_locus_tag="BDH17TP_26170"
     CDS             19339..19524
                     /locus_tag="K5602_RS13785"
                     /old_locus_tag="BDH17TP_26170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000466619.1"
                     /translation="MFGDQRQEATKYVIKEGYQDIYFLNKNGEWYYFEVRSVWRGKHII
                     RVKDGLLGWRKEIVTE"
                     /name="hypothetical protein"
     gene            complement(19743..20486)
                     /locus_tag="K5602_RS13790"
                     /old_locus_tag="BDH17TP_26180"
     CDS             complement(19743..20486)
                     /locus_tag="K5602_RS13790"
                     /old_locus_tag="BDH17TP_26180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843758.1"
                     /translation="MKSVKRLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESATEDKQKKESDNINFESKSDAQIVEILKNQINTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNAR
                     QNVDAQEKTYTTSPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAQREDVSANPND
                     NDSDIEEKSEETEPKKGFWSRLFGN"
                     /name="DUF536 domain-containing protein"
     ARG             10212..11056
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     BGC             7447..17740
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          1193..1340
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="81.333"
                     /coverage="100.0"
                     /evalue="2.96e-25"
     Typing          17593..18452
                     /name="rep_cluster_2214"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(19744..20486)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.866"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          15941..16215
                     /name="MOBV"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="94.565"
                     /coverage="100.0"
                     /evalue="4.71e-46"
ORIGIN
        1 ttggtaataa aacgtttaga aactgtttat ttatataatt ttcgatactt agattatata
       61 atgaataata tcttagtgca agcacctaga ttattaaata aacacaaaaa atgtaagcgt
      121 tttattacct cttaccaaac taaaattcgg aaagaggttt ttattatgtc aattaaactt
      181 tacaacataa atgaggaata cagagaaaag ttttatcaaa taccgaaagt attttttaca
      241 aatcctaaat atatcaagtt atccaatgat gcaaaaatgg catggggtat tcttagagat
      301 cgtttagatt tatcaattaa aaatggttgg gttgattcta aaacaggtaa tatttatttt
      361 tattacaaaa atgaaaaccc acaaaatata ttaaattgta aaaaagataa agtaattaaa
      421 ataaagaaag aacttaattg aagccgaatt actactacaa gaaagacaag gtttaaataa
      481 gacaaataaa ctttatttag ttaaaccaga agtaacagaa gatgatattt ataaaattca
      541 aaagcaagaa aacactgttg agagcagcaa tggcaaggaa gtcggaaaaa ccgacttcaa
      601 gaagtcgata aaacagaatc taatgatact gaacttagct atactgaatc taacaatact
      661 gaaataaatg atatgaatga cttgaatgat atagagtccg aaaatgaaat tagtaatcat
      721 tcaagtcaat gcaaggttat ttaatgcaaa caattttaac tgaatttgaa gaaacacatg
      781 cactttatat gcgccgtaaa aacatgaaac aatataatat ctttaatcaa tcattcaaat
      841 gattttataa caatcaaaga tacatcaaaa tatttcgtta aatcatctga ctttttaact
      901 gatagcgatg aaaaaatcaa gaaattgtca gtgatctaga aaaagatttg tatcgaaaac
      961 gtatgttaag ttatggtgga ttgcttaaat aaaaacataa aattttaaac ttagacgatg
     1021 ctgaagatgg caatttaatt aatacaagtg atgaagataa aatagcaaat gaagaagaaa
     1081 aggcacattc gattacggca attttgaaaa gcaaaattat tatttaaggc attagtgata
     1141 actgatgtct ttttttatta cttttttgta aaaaaagtgc tgtcttattt ttgtgacaaa
     1201 tgctgtatgt agtgtcacaa aagtgtgaca cttgagcttt ttatgacccc acacaaaaac
     1261 attttcgaag ccttgaaata tctggctttg ccagatcccc cattcattga tggggacaaa
     1321 tttcccttat gctcttacgg agattttaga gttaaattaa aatttctaag tttttgataa
     1381 gaaaagccct gcaggaattt agaagaacgt ggggaagttt taaagaattt tatgctaatt
     1441 tttaatttgc atgtaaatgg gcagtgtcta aaaaatagtt attgtttttg ctcaaatttt
     1501 tgtttttgaa aatagcatat atttatttgg ctcatatttg cgttttaaaa gcgtatataa
     1561 gttttagata taaaactata tgaatcaccc ctaaatcttt aaaatgccct cttaaaattc
     1621 aaaataaggg cataaaaaat aaaagccccc cccagataaa gtgaggtagc tttttctttc
     1681 gacgccgtat cgtcgatgta attcaaaaaa gttatgggct ataaatctac atcacttttt
     1741 caagaatgta gtagcaatat tcaacgcaaa ttaattttta taactgctcg gaatatctca
     1801 agccgtttct ttaattttga aataaaaaaa tcgacgaagg tcgattacgt ttttgcacat
     1861 gtcgatttat ccgacgtata agtgcgccct tacgggattt aactagatta taacgacgaa
     1921 ttttagacct gtaaagcaat aacaattagg tctaccaggt agataaagtg tacaaagtag
     1981 aaccgaaaaa gttatttatt ttgaagattt ttcgtagata taatttgcta ataaacttcc
     2041 taaaactgaa taaagaaaaa tagttaaact catgtaatca ctccataatt ctgaagtgtc
     2101 tccatgtcta cgcatagaca cgcatttatg ccgagaaaat ttattgtgcg ttgagaagaa
     2161 cccttaacta aacttgcaga cgaatgtcgg catagcgtga gctattaagc cgaccattcg
     2221 acaagttttg ggattgttaa gggttccgag gctcaacgtc aataaagcaa ttggaataaa
     2281 gcacctatga ttatttaaaa atataagtta taatacattc aaaaatattt ttgaatgagg
     2341 tgtattatga ttcaaacggt tgttgctgct gctgttcttt atattgctac agcagttgat
     2401 ttattagtaa ttttattaat attttttgct agagcaaaga ctagaaaaga atatagaaat
     2461 atttatgttg gtcaatattt agggtctatt attttaatat tagttagttt gtttttagct
     2521 tttgtattaa attatgttcc agaaaagtgg atattaggtt tattgggttt aataccaatt
     2581 tatcttggaa ttaaagtggc tatttatgat gattgtgaag gagaaaagag agctaaaaaa
     2641 gaattgaatg aaaaaggatt gtctaaatta gttggtacgg ttgcaattgt tacgatagca
     2701 agttgtggcg ccgataatat tggtttattt gttccgtatt ttgtgacatt aagtgttact
     2761 aatttattac ttactctgtt tgtcttttta attttaattt tcttcttggt gtttactgca
     2821 caaaaattag ctaatatccc aggaattgga gaaattgttg agaaatttag tcgttggatt
     2881 atggctatca tttatatagc tttaggttta tttattatta ttgaaaatga cactattcaa
     2941 acaattttag gatttatatt ttaatttagg gtgtgatttt atatgagtta tgaaaatact
     3001 tgtgatgtga tctgtgtaca tgaggataaa gttaacaatg ctttaagttt tttagaagat
     3061 gataaatcta agaaattact taacatttta gaaaaaattt gtgatgagaa gaaattgaaa
     3121 atcatattat ctttgattaa agaagatgag ttgtgtgttt gtgatatttc tttgatattg
     3181 aaaatgagtg ttgcttcaac ttcacatcat ttaaggcttt tatataaaaa tgaggtactt
     3241 gatttttata aagatggaaa gatggcatat tattttatta aagacgatga aataagagag
     3301 tttttctcta aaaatcagga gggtttttga aacgagtgaa acgagtttct tcttgtcttg
     3361 atactataaa aaacaaagtt atataacata agacgactta tcggaagtta tctatcatcg
     3421 tatattcgga gatgatataa tatacaggtc gcctatctct caggcgtcaa ttcagacgca
     3481 gagaggaggt gcattacttt gctaatcatt ttcgttcaca tcatagcacc agtcatcagt
     3541 ggctgtgctg ttgcgtatta tacttattgg cttagtaaac gcaacaaata attaataggc
     3601 gactttataa gccagcatcg aaaaaatccc cacactattg cagtagtgtg gggattggtg
     3661 cattaattgt taatcatttt cgttatctag attataacac tggttagtag aggaatgcaa
     3721 aaagataata ttttaagtag tctttttgga tattatcata tgatatattt atgtaaattg
     3781 attttttatt aaaggagcat atatgagtaa tactaaaatt aaatatcaaa tttttatttc
     3841 atcaacttat ttagatttaa tagaagagcg tcaagcagta gtagaagcag ttttaaacag
     3901 taataatatt ccagcaggta tggaactttt taactcaagt agtaaaagcc aatgggaaat
     3961 aataacacaa tggatcaatg aatcagatgc agtgatatta ttgttaggtt ctagttatgg
     4021 aacaattgat agtgaagaaa atattagcta tacagaaatg gagtacaatt ttgctaaatc
     4081 tttaggtaaa cctatatatg tttttgagat gaataaagca tctaccgaat ccgcggaaaa
     4141 gtctaaaaaa ttagatgagt ttaagacaaa agttaaagaa aatagactaa ttagtccaaa
     4201 tattaatgat atttcggaat taaaaagtaa agtatctcag actttaatgc aaagtgtacc
     4261 tagtgaaatt aaagaaaata gtggatggat aagagtacag gattgtggta aaaatgtaaa
     4321 aaaattaaaa aaattggatg ctatacaaag agatttagat acatatgatt ttttgaaaga
     4381 agaactttat aaaatattca tgtatgtaaa aactttttat ttccagcaca caccatttga
     4441 tgatagttat attgaagata tagaaaacta cctgctaaat tatgaaaata atccacataa
     4501 atcattcatg aaaataaaag tttatgatta taaaaacttt ttaaaacatt taaaaaacat
     4561 attgatttta attaaacaag gaaaaaagcc attagctcaa gccggtcatt ttaaattaag
     4621 cttttacgaa gaggatttaa aattgttaca aaaaaattat aagactacgc tagtcgatat
     4681 taaaggattg aataaacatt tttataagga atgtgatagg tgcttaaaag catataatat
     4741 ttttattgag ggtataaata aacatttata tgaatgatat aagtacaccc taatcataca
     4801 tatataattg ttgtcacttt actcgatata tgagaatgac tttacctaat aaatgagaaa
     4861 agcaacgcac tatattaaaa tgcgttgctt tttctattat cgaataccta taactaaact
     4921 atctctagct gtttctacaa cttctgtact tattttatct aaaccattta tatccataat
     4981 tctgtctatc tgcgcaaata aacgatgaat cagcctaaaa ttcccttttg taattttaat
     5041 aatcgtcgtt attgcctcat aatcagtaaa gtcttcgagt tttaaatcaa atcctaagtc
     5101 ttgccactta tattctaata tatgatgcgt ctcatcttta cttagattat caaattcatg
     5161 cgcaaaacct atacgcgaat atagttgagg ataacgagat agttttttct ctatacccgg
     5221 cataccaata aatatcattg ctaaattatg ttcatcataa atagctctta attgctctaa
     5281 atgttgcact ttaaggcgat caatctcatc tactataatt aaatcaatat atttaaacat
     5341 atcactataa tgtttactat gttcatgtcc atacttattt acaacatgta atttttgacc
     5401 caaatcaatg attgcagtaa tactatataa atcattcctt aatttagttt gtttttctgc
     5461 tggtgcatta taaaatattt tatccaccga tagtatgtca tcggtcgttt tactagctaa
     5521 atcttcccaa cctctatggt taacttgttt ttcaatagta tcccaatttg tgtaatacct
     5581 agacgataaa gtttttccga caccaggttg accataacat ataccaatat actgatattt
     5641 aatacaagca tcacaaaatt cagcaaagcg tttatactct ttcgtttcaa tgaaattttg
     5701 atttttagtc attacgatat ctctttaatt ttttgacgtt tttagtcgtt tcttgaggtg
     5761 aataaccaca atttttttct tccttaatta attccgtggt acttggacta gcaatatttt
     5821 gttttaagtg ttttcttctc tgactacgag cgtgctgtat gtcttttata tctatggagt
     5881 aatcagctat ttctggacat atagcagtac aaagaaattc atctctataa aacacacgta
     5941 tttcagccat atcatttggg ttataacgaa tcagtacata ttcacctaca taagcttcta
     6001 gattagtatt actgtatcga aaaccttgaa aatgaatgcc atctgaatga acttttctag
     6061 atttaggtat ttccaacaat aataaatcaa gttgttctaa gctacttggc atattaggga
     6121 aaaagtgatt actattccaa tgactgatag gcgtggtatg aatagtacta tgttcttttt
     6181 gattataatc ttcaattaaa aagtaacgta atttttcttc aaaattgtga aaatttatta
     6241 gattactagg agtatcatta ttgtttatat atccaggcag ttgttctaag aaagtttgat
     6301 taactgtctg aaagaatcgt tctatttttc cacgaccacg aggaacacca actttcgaaa
     6361 acatcaagtt aattttcaaa tcaatagcga cttgttccat atgatgtgaa gtaaagtcac
     6421 ttccatgatc tgtgtagaat ttttcgggta taccacacac tggccaattg gtatcatttt
     6481 tattccatat tgcttggtgt agtgttaatg ctgtgttttg agcattgggg ggcatcaaaa
     6541 cttaagaaat agcctgcaat tgcacgacta tagtcatcca taataatagt tagccatggt
     6601 ctattgatat tacctttttg gtctaatata aagatatcta gcaaagtatg gtctgcttgc
     6661 catatttcat tgggtctcga ggattctcta atttgtatta aatcgtactt attttgatag
     6721 tatttttcac cctgatgaga gaaatcaata acagacttag gcatcgcttt aataacacta
     6781 taaatttgtt tataacttgg tatatcaaaa ttattttctt tacagtaatt agtgattttc
     6841 ctatgaattg tggctatact atttctttta ttcataagcg caaggcgttc aatttcatca
     6901 attatctttg gttctatttt acgtgttcct ttatcagctc ttgtcgcata gattagtcct
     6961 ttaagtcctt gttctttata tgacttattc cacctataaa gggtgcttaa cgcaatccct
     7021 ttacttttag aaatacttga taaagattgt tcgcctagga taaaaggttt tataatattg
     7081 tacttttgag tagctttttt acgtttggct tcagaaaaat tagttagata cttctccttg
     7141 tttttcatct tccttgtcct ccaatttatt gaggtaacga taaattgttg tacgtgaaac
     7201 atgccactgt tctgcaattg tcttaattgg cgtgccatta tcataaaggg tcttaagtaa
     7261 gtttaaatct ttttgattta atttttctgg tctgcctcca tatcggcctc tagcacgtgc
     7321 tgcaattcgg ccagctgaag aacgctctaa aattaaatta cgttcaaatt ctgcaaatgc
     7381 tgcgaataaa tgaaataata attgtccagt tgaacttgat ttatccattg ttatattttc
     7441 ttctaaacta tggaaactta cacctcgttc gttaagctca ttaactaatg tgattaaatc
     7501 ctccatatta cgtcccaatc tatctaatct ccaaacaaca atcgtatctc ctgacctcgc
     7561 aaattcaatt gctttatcta aaccaggtct tttacttttt gaaccactca tatggtcatt
     7621 aaatatcttt tcacaaccat atgtatttaa tcgatcctcc tgtaaattta aattttgtaa
     7681 tccagttgaa actcttgcat aacctatttt caaaatacaa acctcctata tacatcttca
     7741 gtgtaccata acttaattac aaggtctttt atgaacatag attttttgtt gggtttttga
     7801 acacataatc ctatgtaatt cttacttatt tagacataaa agaagagtgt acagaaaatg
     7861 gttattttct gtacactctc atctttaata atatatttta aatgtcatta acaaaactaa
     7921 tttaataaga gtcaagcata gtttacatat gtattatgtt tgaaacatac ctctaattac
     7981 tttttactaa tatcatttaa aatatctcgc aattcttcaa tttctttgtt atttaattct
     8041 tcatttttcg caaaattcaa cactaaactt ttcatatccc ctccatacag tttattaaga
     8101 aaggttttag cagttttcat tttaatatcg tcttctttaa tatttgatga gtaaaaataa
     8161 atattttctg atttgtatcg ttttataatc tcttttttat atagtcttgt gattaatgtt
     8221 ctaatcgttt tatcactaac ttctttatat ttttgaattt caactacaat ttcattagct
     8281 gatactgatt ttttatccca tattatattc ataacatccc attcagccat agatatttca
     8341 acttgcttat tggccattta aaacacccat tccttttaat attttttcac ttattaattc
     8401 agcatttttc ccagacgggt ttccatctga taaatgtgta gcaaaataat acttatcatg
     8461 atttgtaatt acgtaaccta caaaccaccc attattatac ttcccgttta ctatacctgt
     8521 acctgttttc ccatacagtt catacttttc atttttctta atcaataatg aagaagataa
     8581 ttgattcttt gcttttttac taaaatggtt attttgttcc atcatatttt taaaaactat
     8641 tacttgttca agattagata ttttcaaact atcttccatc caatagcttt tataacttcc
     8701 caaattttca ttaccataat ttaattgctt gagttgagcc gcagtatagt tctttggtat
     8761 ttgattacta atacgttcga agtaccaatt aactgaattt tgcattgctg tatttaaatc
     8821 ttgttcctta ttccaagact cgaaaagata atgtttatga ttccatgaca tacgtgaatt
     8881 tttatcactt ataatatgac ggtcaagtcc aaacagtgct aaataaattt tgtaagttga
     8941 atcaggagaa tatctttttc tactttcttt ttcattataa atatagtatt tgtctttctt
     9001 catgctgtac ataacgaaag atccactatt tgaaccaaaa tttttacttt catctaaaat
     9061 ttggtaatcg ctttgtaagg gctttttata attataatca gttaaggatt gccccattaa
     9121 aaactggctt tgaattatca tgataaaaaa agtaaaaata caaataaaaa ttagaattaa
     9181 ttttgactgc tttttcagat cggcttcttt tatattaatt aatctatttt tgagtaatga
     9241 ttttttacca ttaaatgaat ggcttaatat atttttgttg aaaaatgagg tttttaatac
     9301 ggagtccata atagattccg cataagtttt aaattcattt ttgttaatat tattaaggac
     9361 aaatctatcg gcttctactt cattgtcatg aattatcttt ctttttacaa tatgtactaa
     9421 tggattgtaa ctcataataa tagagaagat attaaagata attaaatgta aagtatctct
     9481 atttttagca tgagcatatt catgcagtat tatatatttt agtcttttat caattacact
     9541 tttaaaatat gaactaggaa tcaaaataat atatttccca taccaaaaag ttattggaga
     9601 ttgaatagcc tctgcttttc gaatcacaat atttttttta tattgatggt tgaaaagtat
     9661 cgtatctatt ttattttttt cattttcgtt tagataaagt gactgtttct ttaaatattt
     9721 aagatataat aaggctttca aaaatttaaa acttaaaata ataactaaaa ctatccaaat
     9781 aactgtgcag atattatcaa ttgaatccca attaaactta tggatatctg ttgcgaactc
     9841 ttgaacaggt ttggtggtaa ttatgttatg gttcaagtcg tgtgacttac tttcaactgt
     9901 gggcgcttga ttattcacat tattaaattt tataaaagag aatttaattg ggataaaagg
     9961 aattaatcca gcaagcacag ttagatacca aactttataa tttaaactat aattaaaata
    10021 gcgttttaat atgtacctaa aaaatactaa caatagaaat ataaaacaaa agcttactac
    10081 actcattatt agtaatttag ccattttgac accttctttc aaatatttat aataaacaat
    10141 tgacatcaat attacaattg taatattatt gttttgtaaa aattacaact gtaatatcgg
    10201 agggtttatt ttgaaaaagt taatattttt aattgtaatg gctttagttt taagtgcatg
    10261 taattcaaac agttcacatg ccaaagagtt aaatgattta gaaaaaaaat ataatgctca
    10321 tattggtgtt tatgctttag atactaaaag tggtaaggaa gtaaaattta attcagataa
    10381 gagatttgcc tatgcttcga cttcaaaagc gataaatagt gctattttgt tagaacaagt
    10441 accttataat aagttaaata aaaaagtaca tattaacaaa gatgatatag ttgcttattc
    10501 tcctatttta gaaaaatatg taggaaaaga catcacttta aaagaactta ttgaggcttc
    10561 aatgacatat agtgataata cagcaaacaa taaaattata aaagaaatcg gtggaatcaa
    10621 aaaagttaaa caacgtctaa aagaactagg agataaagta acaaatccag ttagatatga
    10681 gatagaatta aattactatt cgccaaagag caaaaaagat acttcaacgc ctgctgcttt
    10741 cggcaagact ttaaataaac ttatcgcaaa tggaaaatta agcaaaaaaa ataaaaattt
    10801 cttacttgat ttaatgttta ataataaaaa cggagacact ttaattaaag atggtgttcc
    10861 aaaagactat aaggttgctg ataaaagtgg tcaagcaata acatatgctt ctagaaatga
    10921 tgttgctttt gtttatccta agggccaatc tgaacctatt gttttagtca tttttacgaa
    10981 taaagacaat aaaagtgata agccaaatga taagttgata agtgaaaccg ccaagagtgt
    11041 aatgaaggaa ttttaatatt ctaaatgcat aataaatact gataacatct tatagtttgt
    11101 attatatttt ctattatcgt tgacatgtat aattttgata tcaaaacctg attttccctt
    11161 tattattttc gagatttatt ttcttaattc tctttaacaa actagaaata ttgtatatac
    11221 aaaaaatcat aaataataga tgaatagttt aattataggt gttcatcaat cgaaaaagca
    11281 acgtatctta tttaaagtgc gttgcttttt tctcatttat aaggttaaat aattctcata
    11341 tatcaagcaa agtgacataa ttgttgaatt tatagtaact gaaacgtatg attagggtgt
    11401 atattaatta tgagatggaa atcaatgatt gttggctatg cgagagtatc atcgaacgat
    11461 caaaatttag aaagacaact tgaaaattta aagacgtttt gtgctgaaaa aatatttaca
    11521 gaaaaacagt ctgggaaatc tattgaaaat agaccagtac ttcaagaagc acttaacttt
    11581 ttgaggatgg gagatcggtt tgtagtagaa tccattgatt gtttaggtcg taattatgat
    11641 gaagtgattc ataccgttaa ttatttaaaa gacaaagaag tacaattaat gattactagc
    11701 ttacctatga tgaatgaagt ggttggcaat ccattactgg ataagtttat gaaagattta
    11761 attattcaaa tattagcaat ggtttcagaa caagagagaa atgaaagtaa acgtcgacaa
    11821 gcgcaaggaa ttcaagttgc gaaggaaaaa ggcgtatata aagggcgccc cttactttat
    11881 tcaccaaatg ctaaagatcc acagaaacgt attatttatc atcgcgttgt agaaatgtta
    11941 gaagaaggcc aatcaattag taaaattgcg aaagaagtaa atataacaag gcagacgatt
    12001 tacagaatta aaaacgataa tgatttgatt taataaactt tgtttcaatg caactgagag
    12061 cttctcacag cgtctcaaaa cagatgatta taatctatta tgagttttta ataataagac
    12121 aagaaaagag agcgtaaata tgctctctct ttttctcatt aacgaatgtt tataacgcaa
    12181 tcatgatgag agtattaata cagttaatta tttgaaatac tttagtttat ataatgttga
    12241 attataggta gtgaaattgt atttattata cattgtcata tcgttgttta atgatagtta
    12301 atttaaggat aatagaatta atattatata tagatgaaca aaacaagcaa cagagcagaa
    12361 aaaacacttt tagattattt ttactcattc tctattttat ttatttttgc tataataaat
    12421 aaagaatatt aaatggaggt gtttttatga aaaagaaatt tgtttctagt tgtattgcta
    12481 gtacaatctt attcggcact ttattaggtg taacttataa agctgaagct gcaacagtac
    12541 atgtagctgg tggtgtttgg agccatggta ttggaaaaca ttacgtatgg tcttattata
    12601 gtcacaataa aagaaatcat ggttcaacag cagtagggaa atattcatct tttagtggtg
    12661 ttgctcgacc tggtgttcaa tctaaggcat ctgctccaaa ggcttggggt ggaaacaaaa
    12721 cattttatag tcttcactaa ttacatatat taattaagga gaatagacag aattaagtaa
    12781 acttaattct gtctattctc ttgaaagagg caatatgaaa aaattcaaat tatttttaga
    12841 ttttagtact ttattattaa tttcagggct attattttta tttttcttca aagaaaatga
    12901 agaaattata cctgaaagtt ccaatatttt aacaatctct aattgggata aatctaacag
    12961 taaatcaaaa gtgttagatg tcattgaatc aggcgccaaa aatcaaaata tacaaataat
    13021 taaatccgtt aaagattttg ataataaaaa agaatttttt gttttcaact caaaacgaaa
    13081 taattctgac tttatacgta ataaaacatc acttttaact ccatcagatt tattaaacag
    13141 agagataaaa ggaaagtatt atattattgg tgaacatttc aatgtagaag agcttacgag
    13201 tgaattaaaa aaagctggtt taacatctga agttgaatac ataaatagaa acatattatt
    13261 ttttgaatta gtcatagata atgatttatt agtgcctttc atattcttag gcgtattata
    13321 tcttttgtac ttcttatatg acagaggata taatttgaaa ttttatgcta ttcaaaagct
    13381 acatggcttt tcaactacac gcattatttt tcataatatt catataaaaa tcatttattg
    13441 gctagtactt accgctattt tctttattgc taatatatta atcattcata tagccaattt
    13501 agaattggat ttcttaatgt ttattcgtag atttatcgtg ttgctttttg tttttgcttg
    13561 tattactaca ttgctgtggc tgatttcgta tagtcttctt ttgaagttaa gtattccatt
    13621 aatcttaaaa gggaaaaaag gatataagtt ttcaatattt atgggtacct tcaccaaatg
    13681 tatcatggtg ctaatactat cttttttact ggcacaaaat ttaaatgctt atacgaagtt
    13741 aaagaatata tatgactctg aaaaaatctg gcaaaagtta gataattact atacattaga
    13801 gatttctcct aatattagaa attcagaaga aaaacaaatt ttagaaacta atatatacaa
    13861 tttaattaag aaaagcgaac aacttggtgg attgctttta aagaataata atatagccaa
    13921 tcccgataaa aacaattaca ttcctgaaaa tggcaatgtc ttttttatca ataacaattt
    13981 tctgaatttc tataaaaata taaatcatga ttttaaaatg attgacaatc attcggataa
    14041 aataaacgtg tttattcctc caaggttaca atatcaaaaa tctgaaattc aaaaaaatca
    14101 ccaaggatgg attgactttc aaaagcaaca aaacaaaaaa gtagatgtgc aagtactgtc
    14161 aaaaaacgta tctgtttttt cttttgatcg cacaactaat ttgaaatttg ggtatctaga
    14221 ttctccaata gtaatgttgt tgacacttga cgatttaaca ggagattttt atttagctgc
    14281 tgtttctcaa ggtggatatc tatttaaaga tttagataca cttaaacagt tgcttaaaga
    14341 taatcaccta gaagaagaaa ttagcggtat aactaattac aaggattctg tgttaaatga
    14401 attaaatgaa acgaaaacaa aaatgataat aacaatagtt actattatta ttaacgtttt
    14461 cattcttttg atagctactg tatttgaaac aattcaatat tttagctgga ataaaaagca
    14521 actattatta agaaaaattc atggttattc attattcagc agtaatgtac gttatttaac
    14581 aatttctatc ttactttcta ttatgttagc ttacactacg catattttat ttggttcaaa
    14641 gatattacta ttcataataa tgtctattgc tattattcaa catttacttc aaattgctta
    14701 tattaaatat cttgaaaaat actttaaaga tttaatgagg gagatttaaa caatgaaaag
    14761 aactttaatt attgtaacaa ttgtactatt aatcatcata cttagtctgt tattggttag
    14821 aaatgagcat ttagatcgtt ttaacccact gttaaaagaa aaagtatctt atgccaaagt
    14881 tccaaaagat acccaggact atagaaatat aactgtatac tctaaaaatg gagaaaaaaa
    14941 gagttataaa ttggattttt taggttatga tcctacaaaa gaatatgtga aagtaaatca
    15001 taaagggaaa tatgtgcgtt cgatagaata cattacaaaa gatattccta gctttttaaa
    15061 atgaggtgac cgatagtgat aaaacttgaa aatgtttttg taaaaaaagg taataaaaac
    15121 attttagacg gatgtaactt taattttgaa aaaggaaaat catatgcttt agttggagaa
    15181 agtggcgctg gaaaatctac tttacttaac ataatcgctg ggttcgaaga tgtatcacaa
    15241 ggaagcatat atattgaaga taagttacta aaaaagaaag tcgattttta tagatatacg
    15301 ttagggtatt tgtttcaaaa ttttgcttta cttgaaaatc aaacaatcag tcaaaattta
    15361 gatttagccc taaagttcaa aaagaataaa aaagataata tgaacttaaa gaaagaagta
    15421 ttaaaaaagg tcggcctaga tttagatatc aagagaattg ttagttctct aagcggtggt
    15481 gaacaacaaa gagtagcatt ggcaagatta atattaaaag atccgaaaat cattttagct
    15541 gatgaaccta ctgggtcact agatacgaaa aatggaaaaa tagttattga tttattattg
    15601 aagctacttg atgaaaataa aactatgatt gtcgtaacgc atgatttaga gcttgcgaaa
    15661 cgatttgatg tcatagtcaa tatttctgag cttagaagtt aagaaatatt gataggtata
    15721 gccatacata gagaaaaaac aatatgaaat atgattagtc attacttttg agttttttaa
    15781 tttaaggact ggattttcca gtcctttttt atgatgacaa aaaacaagcc tcgcagagca
    15841 cacgttttta atgacttatt tggtttttaa taagtctagt atgttaaaac ttttctgtgt
    15901 ttaggtgtta taatcatatg cagtggaagt tgatttatta tgtcttattc aattattcga
    15961 gttgttaaag tgaaatcaaa aacaaataca agaggtattc aaagacatat tcaaagagaa
    16021 aataaaaatt atgaaaatat agatattgat ttaagtaagt catatttaaa ctatgattta
    16081 gtcaatgata ctaagtttga ttttaataaa aaaattgatg agaaaatcga aaaaaattat
    16141 aaagggaaac gcaaaattag aacagatgcc attaaacata ttgatggatt aattacatca
    16201 gataatgtgt tttttaatca attatctgaa gaagagacaa aatagttttt taagcatgct
    16261 aaagcgttct tggaagaaga atacggtaaa gaaaatcttt tatatgcgac agtacatatg
    16321 gatgagataa caccacatat gcattatggc gtagttccta ttactaaaga tggacgttta
    16381 agtgcgaaag aagttgtagg taataaaaaa gcattaaccg aattccaaga tagattcaat
    16441 acgtatatta ataagcaagg ctatgattta aaacgaggaa tttctagaca acttacaaaa
    16501 gaaaaacatg atcaagttag ccgttataaa caaaaaacag aatatcataa acaaatgcat
    16561 atgcgctaga agcaaataga ggattattta aagcaagaaa atgataaatt gatacaaaac
    16621 taccaaaaat cattagatac gcttaaaaag cttctgagtg tcatgtatga aattaaaact
    16681 aaaaatgtag gtggatggtt tcataaagag aagcaagaaa caggcaatat tgtaattact
    16741 aaaactgatt ttgaaaaata cactaaacaa attaaagcag cacagatgat attagatgat
    16801 tatgaatgta ttaaaagtgg gaagtcatta aaaaaagcag agaaacaaaa tgaaagttta
    16861 gttaatgaat tgactagtgt ccatatggaa aatgaaaagc tggttgaaga atttaatgat
    16921 ttagcacaac gttataatta tttgttgtca gagaatgaaa agaaagataa agaactaaat
    16981 tatacgctta agttattcaa tcaagttttt aaaatcatta aaagtatgat gaaagaagag
    17041 cgttatcata cactaataaa tcatattgat aatcatttag acaattctaa aatacgtgaa
    17101 gtaatgacga tagataacaa tgatgaacag ttctttaaga agaaatatca agcacaagaa
    17161 cgagaaatca tttttaaaga agatagagaa gatggttata cattataaaa atagatattt
    17221 aaatgcattt gtttgaggtt aattattttt taggatgaaa aataggtagc ccccctcgaa
    17281 ctttttaata tatttttata aatcttttta aaaacctttt taggggcttg ttcagcccta
    17341 gagcaacaag ggatttcaat gcctaaagga gtgtttttgc cacataaaag gagtgttttt
    17401 gccacataaa aggagtgttt ttgccacata aaaggagtgt ttttgccaca taaaaggagt
    17461 gttttaaaaa gttgtactcc ttttatggtt tgacattgat aataaagtag tttattgtga
    17521 ataaaagttt tcaaatggga gtgtatattc aaacgatact cctttaggtt cgtaataaag
    17581 ggggctgtat catgacagga gagacagttg tatataaaaa tgaaatgaat ttagttccat
    17641 taaggcgatt tacagctact gaaattaatt tattttttgc gatgtgtaat aaattaaaag
    17701 agcaagatac taatacatta cgtttgtctt ttgatgaatt aaaaaaatta agtaattata
    17761 gtccagaaac acgtaatatt aatagatttg ctaatgattt agataatgtg tataaaaaga
    17821 tgttgaattt aaccattaga tatgaagatg atgatgtaat agaaagattc gttttattca
    17881 atcattatag aatccataag cgagaacaat atctagaaat atcaacttct tcaaatttaa
    17941 aacacatatt gaattcaatt actaataatt ttacaaaatt tgaattaaaa gaaatgacta
    18001 ggcttaaatc tacatattct aaaaatatgt ttagattact taaacaatac aaacatacag
    18061 gctatttaaa aattcacatc gatgatttta aaaatcgttt agatatacct aaatcttatc
    18121 gtatgactga tattaacaaa aatgttttta aacctattat tattgaatta ggttctatat
    18181 ttaataatct tactatcaat aaaatcaaag cgaaaaaagg gcgtaaaatt gaatggatag
    18241 agttcacatt tgacgctgag aaacgcattc ataacaaacg acaacctcaa atgtccaaga
    18301 tagataaatc aagacaatat gtgaggcgtg aaaagacgcc taaatggtta gaagaacggt
    18361 catatgaaaa gcaacctcaa aaagattacg acccacaatt agagaaagaa cgagaggatt
    18421 ttttaaaaca acttgaactg aattgggaat aacgcaactt ttcgttgcga gttggttaac
    18481 taaaagtatc gtgacttttc aattatttta attatagttt gagttaagga gtgattttat
    18541 gaaattagct gaagctataa aagaacagag agaattaaaa ggatggtctc aagaggaatt
    18601 agccaatata ttaaaggttt ccagacaaag tgtttctaaa tgggaaagtg ccaaaaacta
    18661 tccttcctta gatattttga ttgctatgag cgatttattc ggaatctctt tagagcattt
    18721 aattaaagga gatgcacgtt ttaaaaaagt tattttagag ggaaattata gagagagtaa
    18781 cagggtacct tccatagttg attttcttta tgatttttgg tggcttttct ttcctgttgc
    18841 cggattttta gtttgggcca ttcattcgtt catgggttga ttttaaaatc aaaatttaat
    18901 gcacatcagg caatatgaaa aaggaaagta tttttacgac accttgaaat gtattgataa
    18961 gaatagaaga gtttacaaaa ggcaatatga aatatatact aaaagtaaca agaatttcgt
    19021 ttgtaaacgc acaaaacccc gaactacggc gaatagttcg gggttttgtg gtgaattggc
    19081 tttaatcgtc tatattattt tttatcacgt ttatggagct aataaccaaa taacgtaacg
    19141 agacaaccac tgattgcagt tgtcatgatg tgaacaagaa tttcattcat aaatcgcacc
    19201 tcctctctac gccgaattga catctgagag atagacgacc ttcacattat aacaaatctc
    19261 tccttccatg aaataacatg aatattaata aatgttgtta tatattaaag ataaataaat
    19321 ataagggtgg gattgataat gtttggcgat caaagacaag aagctacaaa atatgtcatt
    19381 aaagaaggtt atcaagatat ttatttcctc aacaaaaacg gggaatggta ttatttcgaa
    19441 gtaagaagtg tctggcgtgg caaacatatt attagagtta aagatggttt gttaggttgg
    19501 agaaaagaaa tagtaactga ataaagatac aaaatacttg ccaatgcaaa agaatgaaaa
    19561 cgcgtcaaat caacgatgta taaaagatgc ataaaagata atgaaagtaa aaagccataa
    19621 atgccgtcat ataggcattt atggcttttt gtttggttaa cataatcgat gattatcaga
    19681 agttcaattc acataaaaaa gcacggctaa tttatgaact tgtcgtacct ttttaattaa
    19741 aattagttac caaatagacg actccaaaac ccctttttag gttccgtttc ttcactcttt
    19801 tcttctatat cactatcatt gtcatttgga ttagctgaaa cgtcttctct ttgtgcttct
    19861 tcaccttgtg tactttcgtc gctttgactt ccagatatat ccttatattg aatctctgtt
    19921 tctttagttt cttcctgatc tcggttaata tttacaggac tagtagtata tgttttttct
    19981 tgtgcatcaa cgttttgtct agcgttagta gatgtatcaa agggataatt aaggtgtttt
    20041 tctttttcta attgattttc taatttttga atctttttat tactctctaa tgccagaact
    20101 tgctgattct caagcaattt tgatctttct tgcaactctt ttctgtaaaa ttcaattgtt
    20161 gtttcatgac gactttcttg tttttcaatt tgattattta aagtattaat ctgattttta
    20221 agtatttcta ctatttgagc atcgctttta gattcaaaat taatattatc cgactctttt
    20281 ttttgtttgt cttcagtagc actttcaaaa ccatatttct ttttattttc atttactctt
    20341 tgaatgattt tttctatatc ggtatcttct ttaataaacg aagtgttttc ctgttttatt
    20401 gtctctatat tcaatctctt aatattatta aaaatcgttt gcttactaac ccctaattct
    20461 tcactcaacc tttttacact tttcatatca tcaacccttt ataaaatgtt tataaaccct
    20521 tagtaaaata ttataagctt ataacgatta ataataaagt aatcgacaaa taaaaatata
    20581 aattcgccaa cctttttatc aagggtttgt aaagggttta tggtgtttat caaaggttta
    20641 taaacctata ttttcccttt tttaagttta ttcaaagtgc tataataacc ttaatataac
    20701 aaaaacccca actactggta atagtcgggg t
//
