LOCUS       NZ_AP024204            24496 bp    DNA     circular CON 17-JUN-2024
DEFINITION  Staphylococcus aureus strain SA23-1 plasmid pSA23-1, complete
            sequence.
ACCESSION   NZ_AP024204
VERSION     NZ_AP024204.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMD00256196
            Assembly: GCF_020886635.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1
  AUTHORS   Umeda,K., Ono,H.K., Wada,T., Motooka,D., Nakamura,S., Nakamura,H.
            and Hu,D.L.
  TITLE     High production of egc2-related staphylococcal enterotoxins caused a
            food poisoning outbreak
  JOURNAL   Int J Food Microbiol 357, 109366 (2021)
   PUBMED   34454396
  REMARK    DOI:10.1016/j.ijfoodmicro.2021.109366
REFERENCE   2  (bases 1 to 24496)
  AUTHORS   Umeda,K., Ono,H.K., Wada,T., Motooka,D., Nakamura,S., Nakamura,H.
            and Hu,D.L.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-DEC-2020) Contact:Kaoru Umeda Osaka Institute of
            Public Health, Microbiology; Tojo-cho 8-34, Tennoji-ku, Osaka, Osaka
            543-0026, Japan
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Flye v. 2.7
            Genome Coverage                   :: 100X
            Sequencing Technology             :: ONT MinION; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_020886635.1-RS_2024_06_17
            Annotation Date                   :: 06/17/2024 02:03:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,859
            CDSs (total)                      :: 2,777
            Genes (coding)                    :: 2,679
            CDSs (with protein)               :: 2,679
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 98
            CDSs (without protein)            :: 98
            Pseudo Genes (ambiguous residues) :: 0 of 98
            Pseudo Genes (frameshifted)       :: 58 of 98
            Pseudo Genes (incomplete)         :: 37 of 98
            Pseudo Genes (internal stop)      :: 12 of 98
            Pseudo Genes (multiple problems)  :: 9 of 98
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AP024204.1.
            Annotated by DFAST v.1.2.6 (https://dfast.nig.ac.jp).
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..24496
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="SA23-1"
                     /isolation_source="foodborne patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="pSA23-1"
                     /geo_loc_name="Japan:Osaka"
                     /collection_date="2016"
     gene            10..363
                     /gene="blaI"
                     /locus_tag="SA231_RS14125"
     ARG             2..360
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="99.17"
                     /coverage="95.24"
     gene            627..1220
                     /locus_tag="SA231_RS14130"
                     /old_locus_tag="SA231_26950"
     CDS             627..1220
                     /locus_tag="SA231_RS14130"
                     /old_locus_tag="SA231_26950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690636.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000690638.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNQKDLNLLKTLYDNGTPI
                     KTIAEQWHVSRTTIYRYLNKLEDKEDEKQGEVSN"
                     /name="recombinase family protein"
     gene            1192..2634
                     /locus_tag="SA231_RS14135"
                     /old_locus_tag="SA231_26960"
     CDS             1192..2634
                     /locus_tag="SA231_RS14135"
                     /old_locus_tag="SA231_26960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mu transposase C-terminal domain-containing
                     protein"
                     /protein_id="WP_000790712.1"
                     /translation="MKNKEKYLTNFSEAKRKKATQKYNIIKPFILGEQSLSSISKSKGI
                     ALSTLYRWNKSYKEQGLKGLIYATKADKGTRKIEPKIIDEIERLALMNKRNSIATIHRK
                     TTNYCKENNFDIPSYKQIYSVIKAMPKSVIDFSHQGEKYYQNKYDLIQIRESSRPNEIW
                     QADHTLLDIFILDQKGNINRPWLTIIMDDYSRAIAGYFLSFDAPNAQNTALTLHQAIWN
                     KNDTNWPVCGIPEKFYTDHGSDFTSHHMEQVAIDLKINLMFSKVGVPRGRGKIERFFQT
                     VNQTFLEQLPGYINNNDTPSNLINFHNFEEKLRYFLIEDYNQKEHSTIHTTPISRWNSN
                     HFFPNMPSSLEQLDLLLLEIPKSRKVHSDGIHFQGFRYSNTNLAAYVGEYVLIRYNPND
                     MAEIRVFYRDEFLCTAICPEIADYSIDIKDIQHARSQRRKHLKQNIASPSTTELIKEEK
                     NCGYSPQETTKNVKKLKRYRND"
                     /name="Mu transposase C-terminal domain-containing protein"
     gene            2627..3385
                     /locus_tag="SA231_RS14140"
                     /old_locus_tag="SA231_26970"
     CDS             2627..3385
                     /locus_tag="SA231_RS14140"
                     /old_locus_tag="SA231_26970"
                     /inference="COORDINATES: protein motif:HMM:NF012464.4"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0000150 - DNA strand exchange activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="WP_000164959.1"
                     /translation="MTKNQNFIETKEYKRFAEFCDACIKYQYIGICYGQPGVGKTLSSR
                     YYTNWDTIEKQVNHRGWEDLASKTTDDILSVDKIFYTAPAEKQSGKSIENRPVFQEVLN
                     FLRMGDRLIVESIDRLGRNYEEIIQTVNYLKDKEVQLMITSLPMMNEVIGNPLLDKFMK
                     DLIIQILAMISEQERNESKRRQAQGIQVAKEKGIYKGRPVLYSPNAKDPQKRLVYYRVV
                     ELLEQGKSISTIAKEVGITRQTIYRIKNSK"
                     /name="recombinase family protein"
     gene            3446..3760
                     /gene="arsR"
                     /locus_tag="SA231_RS14145"
                     /old_locus_tag="SA231_26980"
     ARG             3447..3757
                     /name="arsR"
                     /gene="arsR"
                     /gene_name="As(III)-sensing metalloregulatory
                     transcriptional repressor ArsR"
                     /tool="amrfinderplus"
                     /drug_class="ARSENIC"
                     /identity="99.04"
                     /coverage="100.0"
     gene            3757..5049
                     /gene="arsB"
                     /locus_tag="SA231_RS14150"
                     /old_locus_tag="SA231_26990"
     ARG             3761..5046
                     /name="arsB"
                     /gene="arsB"
                     /gene_name="arsenite efflux transporter membrane subunit
                     ArsB"
                     /tool="amrfinderplus"
                     /drug_class="ARSENIC"
                     /identity="99.77"
                     /coverage="100.0"
     gene            5067..5462
                     /locus_tag="SA231_RS14155"
                     /old_locus_tag="SA231_27000"
     CDS             5067..5462
                     /locus_tag="SA231_RS14155"
                     /old_locus_tag="SA231_27000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-dependent arsenate reductase"
                     /protein_id="WP_000358995.1"
                     /translation="MDKKTIYFICTGNSCRSQMAEGWGKEILGEGWNVYSAGIETHGVN
                     PKAIEAMKEVDIDISNHTSDLIDNDILKQSDLVVTLCSDADNNCPILPPNVKKEHWGFD
                     DPAGKEWSEFQRVRDEIKLAIEKFKLR"
                     /name="thioredoxin-dependent arsenate reductase"
     gene            5842..6135
                     /locus_tag="SA231_RS14160"
                     /old_locus_tag="SA231_27010"
     CDS             5842..6135
                     /locus_tag="SA231_RS14160"
                     /old_locus_tag="SA231_27010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="WP_000726502.1"
                     /translation="MKKKFVSSCIASTILFGTLLGVTYKAEAATVHVAGGVWSHGIGKH
                     YVWSYYSHNKRNHGSTAVGKYSSFSGVARPGVQSKASAPKAWGGNKTFYSLH"
                     /name="lactococcin 972 family bacteriocin"
     gene            6210..8144
                     /locus_tag="SA231_RS14165"
                     /old_locus_tag="SA231_27020"
     CDS             6210..8144
                     /locus_tag="SA231_RS14165"
                     /old_locus_tag="SA231_27020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001670421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="WP_000713731.1"
                     /translation="MKKFKLFLDFSTLLLISGLLFLFFFKENEEIIPESSNILTISNWD
                     KSNSKSKVLDVIESGAKNQNIQIIKSVKDFDNKKEFFVFNSKRNNSDFIRNKTSLLTPS
                     DLLNREIKGKYYIIGEHFNVEELTSELKKAGLTSEVEYINRNILFFELVIDNDLLVPFI
                     FLGVLYLLYFLYDRGYNLKFYAIQKLHGFSTTRIIFHNIHIKIIYWLVLTTIFFIANIL
                     IIHIANLELDFLMFIRRFIVLLFVFACITTLLWLISYSLLLKLSIPLTLKGKKGYKFSI
                     FMGTFTKCIMVLILSFLLAQNLNAYTKLKNIYDSEKIWQKLDNYYTLEISPNIRNSEEK
                     QILETNIYNLIKKSEQLGGLLLKNNNIANPDKNNYIPENGNVFFINNNFLNFYKNINHD
                     FKMIDNHSDKINVFIPPRLQYQKSEIQKNHQGWIDFQKQQNKKVDVQVLSKNVSVFSFD
                     RTTNLKFGYLDSPIVMLLTPDDLTGDFYLAAVSQGGYLFKDLDTLKQLLKDNHLEEEIS
                     GITNYKDSVLNELNETKTKMIITIVTIIINVFILLIATVFETIQYFSWNKKQLLLRKIH
                     GYSLFSSNVRYLTISILLSIMLAYTTHILFGSKILLFIIMSIAIIQHLLQIAYIKYLEK
                     YFKDLMREI"
                     /name="bacteriocin-associated integral membrane family
                     protein"
     gene            8148..8459
                     /locus_tag="SA231_RS14170"
                     /old_locus_tag="SA231_27030"
     CDS             8148..8459
                     /locus_tag="SA231_RS14170"
                     /old_locus_tag="SA231_27030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="WP_000831610.1"
                     /translation="MKRTLIIVTIVLLIIILSLLLVRNEHLDRFNPLLKEKVSYAKVPK
                     DTQDYRNITVYSKNGEKKSYKLDFLGYDPTKEYVKVNHKGKYVRSIEYITKDIPSFLK"
                     /name="YxeA family protein"
     gene            8471..9097
                     /locus_tag="SA231_RS14175"
                     /old_locus_tag="SA231_27040"
     CDS             8471..9097
                     /locus_tag="SA231_RS14175"
                     /old_locus_tag="SA231_27040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000593103.1"
                     /translation="MIKLENVFVKKGNKNILDGCNFNFEKGKSYALVGESGAGKSTLLN
                     IIAGFEDVSQGSIYIEDKLLKKKVDFYRYTLGYLFQNFALLENQTISQNLDLALKFKKN
                     KKDNMNLKKEVLKKVGLDLDIKRIVSSLSGGEQQRVALARLILKDPKIILADEPTGSLD
                     TKNGKIVIDLLLKLLDENKTMIVVTHDLELAKRFDVIVNISELRS"
                     /name="ABC transporter ATP-binding protein"
     gene            9335..9978
                     /gene="mobV"
                     /locus_tag="SA231_RS14180"
                     /pseudo=""
     CDS             9335..9978
                     /gene="mobV"
                     /locus_tag="SA231_RS14180"
                     /inference="COORDINATES: protein motif:HMM:NF013258.4"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /name="mobV"
     gene            10045..10545
                     /locus_tag="SA231_RS14185"
                     /old_locus_tag="SA231_27070"
     CDS             10045..10545
                     /locus_tag="SA231_RS14185"
                     /old_locus_tag="SA231_27070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000273007.1"
                     /translation="MYEIKTKNVGGWFHKEKQETGNIVITKTYFEKYTKQIKAAQMILD
                     DYEWIKSGKSLKKSEKQNESLVNELTSVHMENEKLVEEFNDLAQRYNYLLSENEKKDKE
                     LNYTLKLFNQVFKIIKSMMKEERYHTLINHIDNHLDNSKIREVMTIDNNDEQFFKKKYQ
                     AQE"
                     /name="hypothetical protein"
     gene            10908..11768
                     /locus_tag="SA231_RS14190"
                     /old_locus_tag="SA231_27080"
     CDS             10908..11768
                     /locus_tag="SA231_RS14190"
                     /old_locus_tag="SA231_27080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000145511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="WP_000145511.1"
                     /translation="MTGETVVYKNEMNLVPLRRFTATEINLFFAMCNKLKEQDTNTLRL
                     SFDELKKLSNYSPETRNINRFANDLDNVYKKMLNLTIRYEDDDVIERFVLFNHYRIHKR
                     EQYLEISTSSNLKHILNSITNNFTKFELKEMTRLKSTYSKNMFRLLKQYKHTGYLKIHI
                     DDFKNRLDIPKSYRMTDINKNVFKPIIIELGSIFNNLTINKIKAKKGRKIEWIEFTFDA
                     EKRIHNKRQPQMSKIDKSRQYVRREKTPKWLEERSYEKQPQKDYDPQLEKEREDFLKQL
                     ELNWE"
                     /name="replication initiation protein"
     gene            11855..12196
                     /locus_tag="SA231_RS14195"
                     /old_locus_tag="SA231_27090"
     CDS             11855..12196
                     /locus_tag="SA231_RS14195"
                     /old_locus_tag="SA231_27090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761340.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000761344.1"
                     /translation="MKLAEAIKEQRELKRWSQEELANILKVSRQSVSKWESAKNYPSLD
                     ILIAMSDLFGISLEHLIKGDARFKKVILEGNYRESNRAPSIVDFLYDFWWLFFPVAGFL
                     VWAIHSFMG"
                     /name="helix-turn-helix transcriptional regulator"
     gene            12489..12674
                     /locus_tag="SA231_RS14200"
                     /old_locus_tag="SA231_27110"
     CDS             12489..12674
                     /locus_tag="SA231_RS14200"
                     /old_locus_tag="SA231_27110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000466617.1"
                     /translation="MFGDQRQEATKYVIKEGYQDIYFLNKNGEWYYFEVRSAWRGKHII
                     RVKDGLLGWRKEIVTE"
                     /name="hypothetical protein"
     gene            complement(12890..13633)
                     /locus_tag="SA231_RS14205"
                     /old_locus_tag="SA231_27120"
     CDS             complement(12890..13633)
                     /locus_tag="SA231_RS14205"
                     /old_locus_tag="SA231_27120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_000843732.1"
                     /translation="MKSVKKLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESTTEDKQKKGSDNINFESKSDAQIVEILKNQIDTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNTR
                     QNVDAQEKTYTTNPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAKKEDVPANLND
                     NDSDIEEKSEETEPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     gene            14059..15051
                     /locus_tag="SA231_RS14210"
                     /old_locus_tag="SA231_27130"
     CDS             14059..15051
                     /locus_tag="SA231_RS14210"
                     /old_locus_tag="SA231_27130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="WP_064137390.1"
                     /translation="MQNQYFTVQENYKERFYQIPKVFFTSENYKNLTNDMKIAYAILRD
                     RLNLSIKNSWVDEDGNIYFVYSNEKLMEILNCKKEKLTKIKKGLENDGLLIQKRRGLNK
                     PNILYLMKPIVTERDIYKIEKEENDVEPYGEKEVRKSNVQKFENRTSRSSKIERPEVRK
                     SNTNDTDFNDIDFNDTENNDMNDLNDIKYKNEISNHSNHSNHSNQFTHNFDDKEMLLQE
                     FPEQLTNYLLKYDYRDLEIIKAVILKAKKSFNSRHEDMHYMLEDIEDEILTSLKRLKKA
                     IHDRGVKGQKETIKSMQAYLMQTILTELEETHALYMRRKNMKQYNIFNQ"
                     /name="replication initiator protein A"
     gene            <15071..15360
                     /locus_tag="SA231_RS14215"
                     /pseudo=""
     CDS             <15071..15360
                     /locus_tag="SA231_RS14215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009384749.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            15907..16056
                     /locus_tag="SA231_RS14220"
                     /old_locus_tag="SA231_27150"
     CDS             15907..16056
                     /locus_tag="SA231_RS14220"
                     /old_locus_tag="SA231_27150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_000695366.1"
                     /translation="MKIKTFATFTHRQLDKQVNRFLKNDIHVLEIQTHSNWLYISAIVF
                     YEDK"
                     /name="hypothetical protein"
     gene            complement(16224..16916)
                     /locus_tag="SA231_RS14225"
                     /old_locus_tag="SA231_27160"
     CDS             complement(16224..16916)
                     /locus_tag="SA231_RS14225"
                     /old_locus_tag="SA231_27160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative immunity/bacteriocin fusion bifunctional
                     protein"
                     /protein_id="WP_000691527.1"
                     /translation="MKIIKLFSIISLFLLVFSANFSNAYANEEQKSSLLENQKEKLKSK
                     NIEVSQMTKKEISFLEQLQNKNEDMQKFEKQMKKEGFKKIKLEDKNSKLKYLATEANDK
                     NAYGYIANNAYKNEKTKEIVVSETIYDNYNKKITKFIAEKRSMTENKEGKILINKNYVE
                     YKAEKVDKNRPVTYAGFKWNGKAFACSMAGLYACAHYCGVWAIVNPIAGGVCEAVCGTA
                     FAAGCSVG"
                     /name="putative immunity/bacteriocin fusion bifunctional
                     protein"
     gene            17026..17220
                     /locus_tag="SA231_RS14230"
                     /old_locus_tag="SA231_27170"
     CDS             17026..17220
                     /locus_tag="SA231_RS14230"
                     /old_locus_tag="SA231_27170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001004925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_001004925.1"
                     /translation="MNENLEKYIKSLPLLGLLISILLIVLFFFILDVDEDLFVVFLYCL
                     LPLIVNLSIYGFYVFVKRK"
                     /name="hypothetical protein"
     gene            18337..18954
                     /gene="cadD"
                     /locus_tag="SA231_RS14235"
                     /old_locus_tag="SA231_27180"
     ARG             18338..18951
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            18973..19320
                     /locus_tag="SA231_RS14240"
                     /old_locus_tag="SA231_27190"
     CDS             18973..19320
                     /locus_tag="SA231_RS14240"
                     /old_locus_tag="SA231_27190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_000119690.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNHEGF"
                     /name="metalloregulator ArsR/SmtB family transcription
                     factor"
     gene            19477..19569
                     /locus_tag="SA231_RS14245"
     CDS             19477..19569
                     /locus_tag="SA231_RS14245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="WP_001791613.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(19741..20712)
                     /locus_tag="SA231_RS14250"
                     /old_locus_tag="SA231_27200"
     CDS             complement(19741..20712)
                     /locus_tag="SA231_RS14250"
                     /old_locus_tag="SA231_27200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="WP_000481279.1"
                     /translation="MFNAVVVRKSASNVSYKVEKVDESHLSKGDVLVKVVYSSINYKDM
                     LALQYKGGVIRDYPMIPGIDFAGIVESSSNDKFKEGDNVLVTGYDVGVTHTGGFSEYAQ
                     VPGEWIVPIPQEMSIKESMVYGTAGFTAALSIFELEKYGMNIKSQPEILVSGATGGVGS
                     VAIQILHKIGYENITAIVRKEKQIEIAKKLGAKQVIIIEDDNKPLKKGIFDYFLDTVGS
                     NVTLYGLKRLNYQGVATVCGNVAGNSLNANILPFILRGIKLIGIDSVYVDHNIREDIWS
                     KLANEWNIGNSLLYNEIGFEEFYKTIDQLLKGQHLGRTILKV"
                     /name="oxidoreductase"
     gene            20836..21255
                     /locus_tag="SA231_RS14255"
                     /old_locus_tag="SA231_27210"
     CDS             20836..21255
                     /locus_tag="SA231_RS14255"
                     /old_locus_tag="SA231_27210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418034.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_000418035.1"
                     /translation="MELDNCINYLLSTSQNRVFKHFKSLLSPYNITPAEYGVLNCLINS
                     NLNTPKAIGNTLNLEPSTISGILDKMSKKDLITRQTDNENRRTVLINSTNKAKDLWPTL
                     EKKAYQLNNHYFANLTNEETVVFKKILLKINKTTF"
                     /name="MarR family transcriptional regulator"
     gene            complement(21781..22626)
                     /gene="blaZ"
                     /locus_tag="SA231_RS14260"
                     /old_locus_tag="SA231_27220"
     ARG             complement(21785..22626)
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            22734..24491
                     /gene="blaR1"
                     /locus_tag="SA231_RS14265"
                     /old_locus_tag="SA231_27230"
     ARG             22735..24488
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.04"
                     /coverage="100.0"
     ARG             5068..5459
                     /name="arsC"
                     /gene="arsC"
                     /gene_name="thioredoxin-dependent arsenate reductase"
                     /tool="amrfinderplus"
                     /drug_class="ARSENIC"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(21782..22626)
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     BGC             842..11135
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          15417..15564
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="5.980000000000001e-72"
     Typing          10909..11768
                     /name="rep_cluster_2214"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.884"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(12891..13633)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          14060..15051
                     /name="rep_cluster_2100"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="98.691"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          15183..15352
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="93.605"
                     /coverage="91.0"
                     /evalue="1.04e-65"
     Typing          9336..9709
                     /name="MOBV"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="99.2"
                     /coverage="100.0"
                     /evalue="1.03e-73"
ORIGIN
        1 gaaatatcta tggctgaatg ggatgttatg aatataatat gggataaaaa atcagtatca
       61 gctaatgaaa ttgtagttga aattcaaaaa tataaagaag ttagtgataa aacgattaga
      121 acattaatca caagactata taaaaaagag attataaaac gatacaaatc agaaaatatt
      181 tatttttact catcaaatat taaagaagac gatattaaaa tgaaaactgc taaaaccttt
      241 cttaataaac tgtatggagg ggatatgaaa agtttagtgc tgaattttgc gaaaaatgaa
      301 gaattaaata acaaagaaat tgaagaattg cgagacattt taaatgatat tagtaaaaag
      361 taattagagg tatgtttcaa acataataca tatgtaaacc atacttgact cttattaaat
      421 tagttttgtt aatgacattt aaaatatatt attaaagatg agagtgtcca gaaaataacc
      481 attttctgga cactcttctt ttatgtctaa ataagtaaga attacatagg attatgtgtt
      541 caaaaaccca acaaaaaatc tatgttcata aaaggccttg taattaagtt atggtacact
      601 gaagatgtat ataggaggtt tgtattttga aaataggtta tgcaagagtt tcaactggat
      661 tacaaaattt aaatttacag gaggatcgat taaatacata tggttgtgaa aagatattta
      721 atgaccatat gagtggttca aaaagtaaaa gacctggttt agataaagca attgaatttg
      781 cgaggtcagg agatacgatt gttgtttgga gattagatag attgggacgt aatatggagg
      841 atttaatcac attagttaat gagcttaacg aacgaggtgt aagtttccat agtttagaag
      901 aaaatataac aatggataaa tcaagttcaa ctggacaatt attatttcat ttattcgcag
      961 catttgcaga atttgaacgt aatttaattt tagagcgttc ttcagctggc cgaattgcag
     1021 cacgtgctag aggccgatat ggaggcagac cagaaaaatt aaatcaaaaa gatttaaact
     1081 tacttaagac actttatgat aatggcacgc caattaagac aattgcagaa cagtggcatg
     1141 tttcacgtac aacaatttat cgttacctca ataaattgga ggacaaggaa gatgaaaaac
     1201 aaggagaagt atctaactaa tttttctgaa gccaaacgta aaaaagctac tcaaaagtac
     1261 aatattataa aaccttttat cctaggcgaa caatctttat caagtatttc taaaagtaaa
     1321 gggattgcgt taagcaccct ttatagatgg aataagtcat ataaagaaca aggacttaaa
     1381 ggactaatct atgcgacaaa agctgataaa ggaacacgta aaatagaacc aaagataatt
     1441 gatgaaattg aacgccttgc gcttatgaat aaaagaaata gtatagccac aattcatagg
     1501 aaaaccacta attactgtaa agaaaataat tttgatatac caagttataa acaaatttat
     1561 agtgttatta aagcgatgcc taagtctgtt attgatttct ctcatcaggg tgaaaaatac
     1621 tatcaaaata agtacgattt aatacaaatt agagaatcct cgagacccaa tgaaatatgg
     1681 caagcagacc atactttgct agatatcttt atattagacc aaaaaggtaa tatcaataga
     1741 ccatggctaa ctattattat ggatgactat agtcgtgcaa ttgcaggcta tttcttaagt
     1801 tttgatgccc ccaatgctca aaacacagca ttaacactac accaagcaat atggaataaa
     1861 aatgatacca attggccagt gtgtggtata cccgaaaaat tctacacaga tcatggaagt
     1921 gactttactt cacatcatat ggaacaagtc gctattgatt tgaaaattaa cttgatgttt
     1981 tcgaaagttg gtgttcctcg tggtcgtgga aaaatagaac gattctttca gacagttaat
     2041 caaactttct tagaacaact gcctggatat ataaacaata atgatactcc tagtaatcta
     2101 ataaattttc acaattttga agaaaaatta cgttactttt taattgaaga ttataatcaa
     2161 aaagaacata gtactattca taccacgcct atcagtcgtt ggaatagtaa tcactttttc
     2221 cctaatatgc cgagtagctt agaacaactt gatttattat tgttggaaat acctaaatct
     2281 agaaaagttc attcagatgg cattcatttt caaggttttc gatacagtaa tactaatcta
     2341 gcagcttatg taggtgaata tgtactgatt cgttataacc caaatgatat ggctgaaata
     2401 cgtgtgtttt atagagatga atttctttgt actgctatat gtccagaaat agctgattac
     2461 tccatagata taaaagacat acagcacgct cgtagtcaga gaagaaaaca cttaaaacaa
     2521 aatattgcta gtccaagtac cacggaatta attaaggaag aaaaaaattg tggttattca
     2581 cctcaagaaa cgactaaaaa cgtcaaaaaa ttaaagaggt atcgtaatga ctaaaaatca
     2641 aaatttcatt gaaacgaaag agtataaacg ctttgctgaa ttttgtgatg cttgtattaa
     2701 atatcagtat attggtatat gttatggtca acctggtgtc ggaaaaactt tatcgtctag
     2761 gtattacaca aattgggata ctattgaaaa acaagttaac catagaggtt gggaagattt
     2821 agctagtaaa acgaccgatg acatactatc ggtggataaa atattttata ctgcaccagc
     2881 agaaaaacaa tcaggtaaat ctatagaaaa cagacctgtt tttcaagaag tattaaattt
     2941 tttaagaatg ggagatcgtt taattgttga atctattgat agactaggaa gaaattacga
     3001 ggaaataatt caaacagtta attacttaaa agataaagaa gttcagctca tgataacgag
     3061 tttacctatg atgaatgaag tcattggaaa tccactacta gataaattta tgaaagattt
     3121 aattattcaa attttagcaa tgatttcaga acaagaaaga aatgaaagta aacgtcgaca
     3181 agctcaaggg attcaagtcg ccaaagaaaa aggtatatat aaagggagac ctgttctgta
     3241 ttctcccaat gctaaagacc cacaaaagcg tttagtttat taccgagttg ttgaattact
     3301 tgaacagggt aaatctataa gtactatagc taaagaagtt ggtattacac gtcaaactat
     3361 atatagaata aaaaatagta aataaagtaa catagacaat aatctatata gatgttaatc
     3421 tatttaatat ctaggaggtt tattcatgtc ttataaagaa ctatcaacaa tattaaaaat
     3481 tttatcagat ccaagtaggt tagaaatatt agatttactt tcttgtggtg agctatgcgc
     3541 ttgtgactta ttagaacact ttcaattctc acaacctaca ctaagtcatc atatgaagtc
     3601 attagtagat aatgaattag ttacaacacg aaaagatggc aataaacatt ggtatcaact
     3661 taatcatgct attttagatg atattatcca aaacttgaac atcattaata catctaatca
     3721 aagatgtgta tgtaaaaatg tgaaatcagg tgactgttga tgactatttt agcaattgta
     3781 atttttcttt taactttaac ctttgtgatt tggcaaccaa aaggtttaga tattggtatt
     3841 acagctttaa ttggagcggt tgttgctatc attacaggag tcgtaagtct ttctgatgta
     3901 ttagaagtaa caggtattgt ttggaatgca actttaactt ttgtggctgt tattcttatt
     3961 tcattaatat tagatgaaat tggttttttt gaatggtctg cgatacatat ggtcaaggct
     4021 tcaaacggta atggcttaaa aatgtttgtt tttattatgt tacttggggc aattgtagca
     4081 gcatttttcg caaatgatgg tgcagcttta atcttaacgc ctattgtatt agcgatggta
     4141 aggaatctag gatttaatca aaaagtgatt ttccccttta ttattgccag tggttttatt
     4201 gctgatacta catcacttcc cttaattgta agtaacttag ttaatatcgt ttctgcagat
     4261 tacttcgata ttggatttat tgaatatttt agccgaatga tcattcctaa tatattctct
     4321 ctgattgcta gtattctcgt tttatggtta tatttcagaa aatccatacc taaaacgttc
     4381 gatacagaaa atctatcaga tcctaaaagt gcaattaaag attctaagtt atttaagctt
     4441 tcatggatag tattagcagt actactcgtt ggatatcttg ttagcgagtt tatccaaatt
     4501 cctgtatcaa ttattgctgg tattattgct tttatctttg taatattagc tcgtaaatct
     4561 aaagcagttc atacaaaaca agtgattaaa ggtgcaccat ggaatatcgt tgtattctct
     4621 attggtatgt atcttgttgt gtttggacta aaaaatgtag gtattacaac ggtccttggg
     4681 gatgttttaa caaacatttc aaattatggg ttatttagca gcatcatggg tatgggcttt
     4741 atagctgctt tcttatcttc gattatgaac aacatgccaa ctgttttaat agatgcaata
     4801 gcgattggcc aatccagtgc tacaggaata ttaaaagaag gcatggttta tgcgaatgtc
     4861 ataggttctg atttaggacc taaaattacg ccaattggtt ctttagcaac attattgtgg
     4921 ctacatgtct taacacaaaa aggtgtgaag atttcgtggg gaacatactt taaaactgga
     4981 attatcatca ctattccagt cctatttgta acactcttag gtttatacct tacactaatc
     5041 atattttaag aaaaggggct ttaattatgg ataagaaaac aatttatttt atatgtacag
     5101 gaaactcttg tcgtagccaa atggctgaag gttggggaaa ggaaatattg ggtgaaggtt
     5161 ggaatgtcta ttctgctggt attgaaacac atggtgttaa tcctaaagca atagaagcta
     5221 tgaaagaagt agatattgat atatcaaacc atacgtcaga cttgattgat aatgatattt
     5281 taaaacaatc agatttggtc gtaacgttat gtagtgatgc agacaataat tgtcctattt
     5341 taccaccaaa cgttaaaaaa gagcattggg gttttgatga tccagcaggt aaagaatggt
     5401 cagaattcca acgtgttaga gacgagatta aattagctat agaaaagttt aaattgagat
     5461 aatcataaac acctcttatt tagttaataa gaggtgtttt gccatttaaa gaacaaaatt
     5521 tgtgccatat acaatatgcc ctctcttttt ctcattaacg aacgtttata acgcaatcat
     5581 gatgagagta ttaatacagt taattatttg aaatacttta gtttacataa tgttgaatta
     5641 taggtagtga aattgtattt attatacatt gtcatatcgt tgtttaatga tagttaattt
     5701 aaggataata gaattaatat tatatataga tgaacaaaac aagcaacaga gcaaaaaaac
     5761 acttttagat tatttttact cattctctat tttatttatt tttgctataa taaataaaga
     5821 atattaaatg gagttgtttt tatgaaaaag aaatttgttt ctagttgtat tgctagtaca
     5881 atcttattcg gcactttatt aggtgtaact tataaagctg aagctgcaac agtacatgta
     5941 gctggtggtg tttggagcca tggtattgga aaacattacg tatggtctta ttatagtcac
     6001 aataaaagaa atcatggttc aacagcagta gggaaatatt catcttttag tggtgttgct
     6061 cgacctggtg ttcaatctaa ggcatctgct ccaaaggctt ggggtggaaa caaaacattt
     6121 tatagtcttc actaattaca tatattaatt aaggagaata gacagaatta agtaaactta
     6181 attctgtcta ttctcttgaa agaggcaata tgaaaaaatt caaattattt ttagatttta
     6241 gtactttatt attaatttca gggctattat ttttattttt cttcaaagaa aatgaagaaa
     6301 ttatacctga aagttccaat attttaacaa tctctaattg ggataaatct aacagtaaat
     6361 caaaagtgtt agatgtcatt gaatcaggcg ccaaaaatca aaatatacaa ataattaaat
     6421 ccgttaaaga ttttgataat aaaaaagaat tttttgtttt caactcaaaa cgaaataatt
     6481 ctgactttat acgtaataaa acatcacttt taactccatc agatttatta aacagagaga
     6541 taaaaggaaa gtattatatt attggtgaac atttcaatgt agaagagctt acgagtgaat
     6601 taaaaaaagc tggtttaaca tctgaagttg aatacataaa tagaaacata ttattttttg
     6661 aattagtcat agataatgat ttattagtgc ctttcatatt cttaggcgta ttatatcttt
     6721 tgtacttctt atatgacaga ggatataatt tgaaatttta tgctattcaa aagctacatg
     6781 gcttttcaac tacacgcatt atttttcata atattcatat aaaaatcatt tattggctag
     6841 tacttaccac tattttcttt attgctaata tattaatcat tcatatagcc aatttagaat
     6901 tggatttctt aatgtttatt cgtagattta tcgtgttgct ttttgttttt gcttgtatta
     6961 ctacattgtt gtggctgatt tcgtatagtc ttcttttgaa gttaagtatt ccattaacct
     7021 taaaagggaa aaaaggatat aagttttcaa tatttatggg taccttcacc aaatgtatca
     7081 tggtgctaat actatctttt ttactggcac aaaatttaaa tgcttatacg aagttaaaga
     7141 atatatatga ctctgaaaaa atctggcaaa agttagataa ttactataca ttagagattt
     7201 ctcctaatat tagaaattca gaagaaaaac aaattttaga aactaatata tacaatttaa
     7261 ttaagaaaag cgaacaactt ggtggattgc ttttaaagaa taataatata gccaatcccg
     7321 ataaaaacaa ttacattcct gaaaatggca atgtcttttt tatcaataac aattttctga
     7381 atttctataa aaatataaat catgatttta aaatgattga caatcattcg gataaaataa
     7441 acgtgtttat tcctccaagg ttacaatatc aaaaatctga aattcaaaaa aatcaccaag
     7501 gatggattga ctttcaaaag caacaaaaca aaaaagtaga tgtgcaagta ctgtcaaaaa
     7561 acgtatctgt tttttctttt gatcgcacaa ctaatttgaa atttggatat ctagattctc
     7621 caatagtaat gttgttgaca cctgacgatt taacaggaga tttttattta gctgctgttt
     7681 ctcaaggtgg atatctattt aaagatttag atacacttaa acagttgctt aaagataatc
     7741 acctagaaga agaaattagc ggtataacta attacaagga ttctgtgtta aatgaattaa
     7801 atgaaacgaa aacaaaaatg ataataacaa tagttactat tattattaac gttttcattc
     7861 ttttgatagc tactgtattt gaaacaattc aatattttag ctggaataaa aagcaactat
     7921 tattaagaaa aattcatggt tattcattat tcagcagtaa tgtacgttat ttaacaattt
     7981 ctattttact ttctattatg ttagcttaca ctacgcatat tttatttggt tcaaagatat
     8041 tactattcat aataatgtct attgctatta ttcaacattt acttcaaatt gcttatatta
     8101 aatatcttga aaaatacttt aaagatttaa tgagggagat ttaaacaatg aaaagaactt
     8161 taattattgt aacaattgta ctattaatca tcatacttag tctgttattg gttagaaatg
     8221 agcatttaga tcgttttaac ccactgttaa aagaaaaagt atcttatgcc aaagttccaa
     8281 aagataccca ggactataga aatataactg tatactctaa aaatggagaa aaaaagagtt
     8341 ataaattgga ttttttaggt tatgatccta caaaagaata tgtgaaagta aatcataaag
     8401 ggaaatatgt gcgttcgata gaatacatta caaaagatat tcctagcttt ttaaaatgag
     8461 gtgaccgata gtgataaaac ttgaaaatgt ttttgtaaaa aaaggtaata aaaacatttt
     8521 agacggatgt aactttaatt ttgaaaaagg aaaatcatat gctttagttg gagaaagtgg
     8581 cgctggaaaa tctactttac ttaacataat cgctgggttc gaagatgtat cacaaggaag
     8641 catatatatt gaagataagt tactaaaaaa gaaagtcgat ttttatagat atacgttagg
     8701 gtatttgttt caaaattttg ctttacttga aaatcaaaca atcagtcaaa atttagattt
     8761 agccctaaag ttcaaaaaga ataaaaaaga taatatgaac ttaaagaaag aagtattaaa
     8821 aaaggtcggc ctagatttag atatcaagag aattgttagt tctctaagcg gtggtgaaca
     8881 acaaagagta gcattggcaa gattaatatt aaaagatccg aaaatcattt tagctgatga
     8941 acctactgga tcactagata cgaaaaatgg aaaaatagtt attgatttat tattgaagct
     9001 acttgatgaa aataaaacta tgattgtcgt aacgcatgat ttagagcttg cgaaacgatt
     9061 tgatgtcata gtcaatattt ctgagcttag aagttaagaa atattgatag gtatagccat
     9121 acatagagaa aaaacaatat gaaatatgat tagtcattac ttttgagttt tttaatttaa
     9181 ggactggatt ttccagtcct tttttgtgat gacaaaaaac aagcctcgca gagcacacgt
     9241 ttttaatgac ttatttggtt tttaataagt ctagtatgtt aaaacttttc tgtgtttagg
     9301 tgttataatc atatgcagtg gaagttgatt tattatgtct tattcaatta ttcgagttgt
     9361 taaagtgaaa tcaaaaacaa atacaagagg tattcaaaga gaaaataaaa attatgaaaa
     9421 tatagatatt gatttaagta agtcatattt aaactatgat ttagtcaatg atactaagtt
     9481 tgattttaat aaaaaaattg atgagaaaat cgaacaaaat tataaaggga aacgcaaaat
     9541 tagaacagat gccattaaac atattgatgg attaattaca tcagataatg tgtttttaat
     9601 caattatctg aagaagagac aaaatagttt tttaagcatg ctaaagcgtt cttggaagaa
     9661 gaatacggta aagaaaatct tttatatgcg acagtacata tggatgagat aacaccacat
     9721 atgcattatg gcgtaattcc tattactaaa gatggacgtt taagtgcgaa agaagttgta
     9781 ggtaataaaa aagcattaac cgaattccaa gatagattca atacgtatat taataagcaa
     9841 ggctatgatt taaaacgagg aatttctaga caacttacaa aagaaaaaca tgatcaagtt
     9901 agcggctata aacaaaaaac agaatatcat aaacaaatgt atatgcgcga gaagcaaata
     9961 gaggatcatt taaagtaaga aaatgataaa ttgatacaaa actaccaaaa atcattagat
    10021 acgcttaaaa agcttctgag tgtcatgtat gaaattaaaa ctaaaaatgt aggtggatgg
    10081 tttcataaag agaagcaaga aacaggcaat attgtaatta ctaaaactta ttttgaaaaa
    10141 tacactaaac aaattaaagc agcacagatg atattagatg attatgaatg gattaaaagt
    10201 gggaagtcat taaaaaaatc agagaaacaa aatgaaagtt tagttaatga attgactagt
    10261 gtccatatgg aaaatgaaaa gctggttgaa gaatttaatg atttagcaca acgttataat
    10321 tatttgttgt cagagaatga aaagaaagat aaagaactaa attatacgct taagttattc
    10381 aatcaagttt ttaaaatcat taaaagtatg atgaaagaag agcgttatca tacgctaata
    10441 aatcatattg ataatcattt agacaattct aaaatacgtg aagtaatgac gatagataac
    10501 aatgatgaac agttctttaa gaagaaatat caagcacaag aatgagaaat catttttaaa
    10561 gaagatagag aagatggtta tacattataa aaatagatat ttaaatgcat ttgtttgagg
    10621 ttaattattt tttaggatga aaaataggta gcccccctct aactttttaa tatattttta
    10681 taaatctttt taaaaatctt ttaggggctt gttcagacct agagcaacaa gggatttcaa
    10741 tgcctaaagg agtgtttttg ccacataaaa ggggtgtttt aaaaagttgt actcctttta
    10801 tggtttgaca ttgataataa agtagtttat tgtgaataaa agttttcaaa tgggagtgta
    10861 tattcaaacg atactccttt aggttcgtaa taaagggggg ctgtatcatg acaggagaga
    10921 cagttgtata taaaaatgaa atgaatttag ttccattaag gcgatttaca gctactgaaa
    10981 ttaatttatt ttttgcgatg tgtaataaat taaaagagca agatactaat acattacgtt
    11041 tgtcttttga tgaattaaaa aaattaagta attatagtcc agaaacacgt aatattaata
    11101 gatttgctaa tgatttagat aatgtgtata aaaagatgtt gaatttaacc attagatatg
    11161 aagatgatga tgtaatagaa agattcgttt tattcaatca ttatagaatc cataagcgag
    11221 aacaatatct agaaatatca acttcttcaa atttaaaaca catattgaat tcaattacta
    11281 ataattttac aaaatttgaa ttaaaagaaa tgactaggct taaatctaca tattctaaaa
    11341 atatgtttag attacttaaa caatacaaac atacaggcta tttaaaaatt cacatcgatg
    11401 attttaaaaa tcgtttagat atacctaaat cttatcgtat gactgatatt aacaaaaatg
    11461 tttttaaacc tattattatt gaattaggtt ctatatttaa taatcttact atcaataaaa
    11521 tcaaagctaa aaaagggcgt aaaattgaat ggatagagtt cacatttgac gctgagaaac
    11581 gcattcataa caaacgacaa cctcaaatgt ccaagataga taaatcaaga caatatgtga
    11641 ggcgtgaaaa gacgcctaaa tggttagaag aacggtcata tgaaaagcaa cctcaaaaag
    11701 attacgaccc acaattagag aaagaacgag aggatttttt aaaacaactt gaactgaatt
    11761 gggaataacg caacttttcg ttgcgagttg gttaactaga agtatcgtga cttttcaatt
    11821 attttaatta tagtttgagt taaggagtga ttttatgaaa ttagctgaag ctataaaaga
    11881 acagagagaa ttaaaaagat ggtctcaaga ggaattagcc aatatattaa aggtttccag
    11941 acaaagtgtt tctaaatggg aaagtgccaa aaactatcct tccttagata ttttgattgc
    12001 tatgagcgat ttatttggaa tctctttaga gcatttaatt aaaggagatg cacgttttaa
    12061 aaaagttatt ttagagggaa attatagaga gagtaacagg gcaccttcca tagttgattt
    12121 tctttatgat ttttggtggc ttttctttcc tgttgccgga tttttagttt gggccattca
    12181 ttcgttcatg ggttgatttt aaaatcaaaa tttaatgcac atcaggcaat atgaaaaagg
    12241 aaagtatttt tacgacacct tgaaatgtat tgataagaat agaagagttt acaaaaggca
    12301 atatgaaata tatactaaaa gtaacaagaa tttcattcat aaatcgcacc tcctctctac
    12361 gccgaattga cgtctgagag atagacgacc ttcacattat aacaaatctc ttcttccatg
    12421 aaataacatg aatattaata aatgttgtta tatattaaag ataaataaat ataagggtgg
    12481 gattgataat gtttggcgat caaagacaag aagctacaaa atatgtcatt aaagaaggtt
    12541 atcaagatat ttatttcctc aacaaaaacg gggaatggta ttatttcgaa gtaagaagtg
    12601 cctggcgtgg caaacatatt attagagtta aagatggttt gttaggttgg agaaaagaaa
    12661 tagtaactga ataaagatac aaaatacttg ccaatgcaaa agaatgaaaa cgcgtcaaat
    12721 caacgatgta taaaagatgc ataaaagata atgaaagtaa aaagccataa atgcctatat
    12781 gacggcattt atggcttttt gtttggttaa cataatcgat gattaccaga agttctcact
    12841 atataaaaga cactaaaatt ttataacttt tagtgcctaa tcaattattt tagctaccaa
    12901 acaaacgact ccaaaacccc tttttaggtt ccgtttcttc actcttttct tctatatcac
    12961 tatcattgtc atttagatta gctggaacgt cttctttttt tgcttcttca ccttgtgtac
    13021 tttcgtcgct ttgacttcca gatatatcct tatattgaat ctctgtttct ttagtttctt
    13081 cctgatctct gttaatattt acaggattag tagtatatgt tttttcttgt gcatcaacgt
    13141 tttgtctagt gttagtagat gtatcaaagg gataattaag gtgtttttct ttttctaatt
    13201 gattttctaa tttttgaatc tttttattac tctctaatgc cagaacttgc tgattttcaa
    13261 gcaattttga tctttcttgc aactcttttc tgtaaaattc aattgttgtt tcatgacgac
    13321 tttcttgttt ttcaatttga ttatttaaag tatcaatctg atttttaagg atttctacta
    13381 tttgagcatc gcttttcgat tcaaaattaa tattatccga cccttttttt tgtttgtctt
    13441 cagtagtact ttcaaaacca tatttctttt tattttcatt tactctttga atgatttttt
    13501 ctatatcggt atcttcttta ataaacgaag tgttttcctg ttttattgtc tctatattca
    13561 atcgcttaat attattaaaa atcgtttgct tactaacccc taattcttca ctcaactttt
    13621 tcacactttt catatcatca accctttata aaatgtttat aaacccttga taaaatatta
    13681 taagcttata atgcttaata ataaagtgat taataaataa aaataaacat ccatcaacct
    13741 ttttatcaag ggtttatgaa aggtttatga tatttatcaa gggtttataa acccttgata
    13801 aagctatatt ttccctttta taagtttatt taaagtgcta taataaactt aatataacaa
    13861 aaaccccaac tactggtaat agtcggggtt tggtaataaa acgtttagaa actgtttatt
    13921 tatataattt tcgatacttg tattatataa tgaataatat cttagtgcaa gcacctaaat
    13981 cattaaataa atgtaaagct aaataaaaac gttttattac ctcttaccaa actaaaatat
    14041 ggaaagaggt tttttgtcat gcaaaatcaa tattttacag tgcaagaaaa ttacaaagaa
    14101 agattttatc aaatccctaa agtattcttt accagtgaaa attataaaaa tctaactaat
    14161 gatatgaaaa tagcctatgc tatcttacgt gatcgcttaa atttatctat taaaaatagc
    14221 tgggttgatg aagatggtaa catttacttt gtttattcaa atgaaaagct aatggaaatc
    14281 ttaaattgta aaaaagaaaa gttaacaaaa ataaaaaaag ggttagaaaa cgatggtcta
    14341 ctcattcaaa aacgacgtgg tttaaataaa ccaaatattc tatatttaat gaaacctatt
    14401 gtcacagaac gtgatattta caaaatagaa aaagaagaaa acgatgttga accttacggc
    14461 gagaaggaag ttcgaaaatc gaacgtccag aagttcgaaa atcgaacgtc cagaagttcg
    14521 aaaatcgaac gtccagaagt tcgaaaatcg aacactaatg atactgactt taatgacatt
    14581 gactttaatg atactgagaa taatgatatg aatgacttga atgatataaa gtacaaaaat
    14641 gaaattagta atcattcaaa tcattcaaat cattcaaatc aatttacaca taattttgat
    14701 gataaagaaa tgctattgca agaattccca gaacaactaa ctaattattt attaaaatat
    14761 gattatagag atttagaaat cataaaggct gttattctta aagcaaaaaa atcatttaat
    14821 tcaaggcatg aagatatgca ttacatgtta gaggacattg aggatgaaat attaacttct
    14881 ttaaaaagac ttaaaaaagc tatacatgat aggggagtta aaggccaaaa ggaaacaatc
    14941 aagtcaatgc aagcttattt aatgcaaaca attctaactg aacttgaaga aacacatgcc
    15001 ctttatatgc gccgtaaaaa catgaaacaa tataatatct ttaatcaata attcaaatga
    15061 ttttataaca ctcgaagaga catcaaaata ttccgttaaa tcatctgact ttttaactga
    15121 tgacgacgaa aaaaatcaag aaattgtaag tgatttagaa aaaggtttgt atcgaaaacg
    15181 tatgttaagt tatggtggat tgcttaaaca aaagcataaa attttaaact tagacgatgc
    15241 cgaagatggt aatttgatta atacaagtga tgaagataaa acgacagacg aagaaaaaaa
    15301 gcacattcaa ttaccgcaat ttggaatttc gaaaagcaaa attattattt aagacattag
    15361 tgataactga tgtctttttt tattgttttt ctgtaaaaaa gtgctgtctt atttttgtga
    15421 caaatgctgt atgtagtgtc acaaaagtgt gacactacag ctttgtatga tatcacttta
    15481 aaataactta aaacccttgg aatgtctggc cttgccagat ctatcatttt tgaatgatag
    15541 caaatttccc ttatgctctt acggagattt tagagttaaa ttaaaatttc taagtttttg
    15601 ataagaaaag ccctgcagga atttagaaaa acatggggaa gttttaaagt attttatgct
    15661 aatttttaaa tttgcatgta aatgggcagt atctaaaaaa ttagtcactg attttgctga
    15721 aatttttgtt tgtgaaatta gcatatattt atttggctca tatttgcgtt ttaagagact
    15781 gtatagattt ttaagtacaa aacctatatg atttgcctct aagtcttcaa aatgcctctt
    15841 aaaatccaaa ataaaagtgt ttaatattgt aataaggatt gctattttta taaaaggaga
    15901 gatatcatga agattaaaac tttcgctact tttactcatc gtcaattaga taaacaagtt
    15961 aataggtttt taaagaatga tattcatgta ttagaaattc aaacacacag taattggtta
    16021 tatatttcag ctattgtttt ttatgaggat aaataaggaa catcgtattt atgccgaaaa
    16081 aatttattga tgttgagaag aacccttaac taaacttgca gacgaatgtc ggcatagcgt
    16141 gagctattaa gccgaccatt cgacaagttt tgggattgtt aagggttccg aggctcaacg
    16201 tcaataaaac aattggaata aaatcaacct acagagcatc cagctgcaaa tgcagttccg
    16261 caaactgctt cacatacacc gccggctatt ggatttacga ttgcccatac tccacagtag
    16321 tgagcacatg cataaagtcc agccatacta caagcgaatg ctttgccgtt ccatttgaat
    16381 cctgcatatg ttaccggtct gtttttatca actttttcag ccttatattc aacgtaattt
    16441 ttgttaataa gtatttttcc ctctttgttt tcagtcatac ttcttttttc ggcaatgaat
    16501 tttgtgattt ttttgttgta gttatcatat attgtttcag aaactacaat ttcttttgtt
    16561 ttttcatttt tataagcgtt attagctatg tagccatatg catttttatc atttgcttct
    16621 gtagctagat attttaattt agaatttttg tcttctagct ttattttttt aaatccttct
    16681 tttttcattt gcttttcgaa tttttgcata tcttcatttt tattttgcaa ttgttctaga
    16741 aaacttattt ctttcttggt catttgtgat acttcgatgt ttttgctttt caatttttct
    16801 ttttgatttt ctagtaaaga acttttttgt tcttcatttg cgtaagcatt agaaaaattc
    16861 gcgctaaata ccagtaggaa caaggaaatt attgaaaata attttataat tttcatttga
    16921 tacctccaag ataataagat attttaattg tataagtaag cgctttataa aatcaatatt
    16981 tattttaata tatttataaa catatttttg aaaggagtct attttatgaa tgaaaattta
    17041 gaaaaatata taaaaagttt gccactttta ggtttgttaa ttagtatttt gttaattgtt
    17101 ttattctttt ttattttaga tgttgatgaa gatttattcg tggttttttt atactgttta
    17161 ttgcctttga tagttaattt gtctatttat ggtttttatg tttttgttaa aagaaagtaa
    17221 gattatgaat aattttgttt ttaatttgta tgctttgagg gggttggaaa acggtaggtg
    17281 tatagattag atttcttgtt tttttgaaac gagtgtgaac gagtttcttc ttgtcttgat
    17341 ttttgataaa aacgccctac aggaatttag aaaaacgtgg ggaagtttta aagaatttta
    17401 tgctaatttt taatttgcat gtaaatgggc agtgtctaaa aatagttatt gtttttgctc
    17461 aaatttttgt ttttgaaaat agcatatatt tatttggctc atatttgcgt tttaaaagca
    17521 tatataagtt ttagatataa aactatatga atcaccccta aatctttaaa atgccctctt
    17581 aaaattcaaa ataagggcat aaaaaataaa agctacccca gataaagtga ggtagctttt
    17641 tctttcatac ggtctattta tttttctttc gacgccgtat cgtcgatgta attcaaaaaa
    17701 gttatgggct ataaatctac atcacttttt caagaatgta gtagcaatat tcaacgcaaa
    17761 ttaattttta taactgctcg gaatatctca agccgtttct ttaattttga aataaaaaaa
    17821 tcgacgaagg tcgattacgt ttttgcacat gtcgatttat ccgacgtata agtgcgccct
    17881 tacgggattt aactagatta taacgacgaa ttttagacct gtaaagcaat aacaattagg
    17941 tctaccaggt agataaagtg tacaaagtag aaccgaaaaa gttatttatt ttgaagattt
    18001 ttcgtagata taatttgcta ataaacttcc taaaactgaa taaagaaaaa tagttaaact
    18061 catgtaatca ctccataatt ctgaagtgtc tccatgtcta cgcatagaca cgcatttatg
    18121 ccgagaaaat ttattgtgcg ttgagaagaa cccttaacta aacttgcaga cgaatgtcgg
    18181 catagcgtga gctattaagc cgaccattcg acaagttttg ggattgttaa gggttccgag
    18241 gctcaacgtc aataaagcaa ttggaataaa gcacctatga ttatttaaaa atataagtta
    18301 taatacattc aaaaatattt ttgaatgagg tgtattatga ttcaaacggt tgttgctgct
    18361 gctgttcttt atattgctac agcagttgat ttattagtaa ttttattaat attttttgct
    18421 agagcaaaga ctagaaaaga atatagagat atttatgttg gtcaatattt agggtctatt
    18481 attttaatat tagttagttt gtttttagct tttgtattaa attatgttcc agaaaagtgg
    18541 atattaggtt tattgggttt aataccaatt tatcttggaa ttaaagtggc tatttatgat
    18601 gattgtgaag gagaaaagag agctaaaaaa gaattgaatg aaaaaggatt gtctaaatta
    18661 gttggtacgg ttgcaattgt tacgatagca agttgtggcg ccgataatat tggtttattt
    18721 gttccgtatt ttgtgacatt aagtgttact aatttattac ttactctgtt tgtcttttta
    18781 attttaattt tcttcttggt gtttactgca caaaaattag ctaatattcc aggaattgga
    18841 gaaattgttg agaaatttag tcgttggatt atggctatta tttatatagc tttaggttta
    18901 tttattatta ttgaaaatga cactattcaa acaattttag gatttatatt ttaatttagg
    18961 gtgtgatttt atatgagtta tgaaaatact tgtgatgtga tctgtgtaca tgaggataaa
    19021 gttaacaatg ctttaagttt tttagaagat gataaatcta agaaattact taacatttta
    19081 gaaaaaattt gtgatgagaa gaaattgaaa atcatattat ctttgattaa agaagatgag
    19141 ttgtgtgttt gtgatatttc tttgatattg aaaatgagtg ttgcttcaac ttcacatcat
    19201 ttaaggcttt tatataaaaa tgaggtactt gatttttata aagatggaaa gatggcatat
    19261 tattttatta aagacgatga aataagagag tttttctcta aaaatcatga gggtttttga
    19321 aacgagtttc ttcttgtctt gatactataa aaaacaaagt tatataacat aagacgactt
    19381 atcggaagta gatatgcttg tatattcaca gatggtataa taatagagtc gcctatctct
    19441 caggcgtcaa ttgacgaaga gaggaggtgc attactttgc taatcatttt cgttcacatc
    19501 atagcaccag tcatcagtgg ctgtgctgtt gcgtattata cttattggct tagtaaacgc
    19561 aacaaataat taataggcga ctttataagc cagcatcgaa aaaatcccca cactactgca
    19621 atagtgtggg gattggtgca ttaattgtta atcattttcg ttatataaat tataacactg
    19681 gttagtagag aaatgcaaaa tgattgaatt aatagtaaat gtattaatga atactcacac
    19741 ttatactttt aaaatagttc ttcctaaatg ttgtcctttt aaaagctgat ctatcgtttt
    19801 atagaattct tcaaatccaa tttcattgta tagaagtgaa tttcctatat tccattcatt
    19861 tgctaactta ctccatatat cttcacggat attatgatca acatatacag aatcaatgcc
    19921 aattaattta atacctctaa gaataaacgg taatatatta gcgttaagtg aatttcctgc
    19981 tacatttcca catacagtag caacaccttg ataatttaga cgttttaaac cgtataatgt
    20041 tacattactc cccactgtat ctaagaaata atcaaaaata ccttttttaa gcggtttatt
    20101 atcatcttca attattatta cttgttttgc acctaatttt tttgcgattt ctatttgctt
    20161 ttcttttctt acgatagcag tgatattttc atatccaatt ttatgtaaaa tttgtatagc
    20221 aacactgccc acaccacctg tagccccaga cactaaaatt tcaggttgtg atttgatatt
    20281 cattccatat ttttctagtt caaaaattga taatgctgcc gtaaaaccgg ctgtgccata
    20341 taccatagac tctttaatag acatttcttg gggaatagga acaatccact ctccaggcac
    20401 ttgtgcatat tctgaaaatc cacctgtatg tgtcacgcca acatcataac cagtaactaa
    20461 tacattatcg ccttctttaa acttatcatt cgaacttgat tcaacaatac ctgcaaaatc
    20521 tataccagga atcataggat aatctctaat tacaccgcct ttatattgta aagctagcat
    20581 atccttataa tttattgaag agtataccac ttttactaat acatcaccct tcgataaatg
    20641 agattcatca actttttcta ctttataact aacatttgat gcactttttc tcactactac
    20701 cgcattgaac atttattagc cttctttcac aattgttttg tagaagtatg tttttgttgc
    20761 aaaactattt tcctacaaaa cttatcatga tatgataagc gagtcaatac taatgattta
    20821 agagaggttt tagttgtgga attagataat tgtataaatt atttgttgag tacttctcag
    20881 aatagagttt ttaaacattt taaaagttta ttaagtccct ataatattac tccagcagaa
    20941 tatggtgttt tgaattgctt gattaatagt aatttgaata cacctaaagc gattggtaat
    21001 actttaaatt tagaaccttc aacaatatct ggaatattag ataagatgtc caaaaaggat
    21061 ctaataacac gtcaaactga taatgaaaat agaagaactg tgctaataaa cagtacaaat
    21121 aaagcaaaag acttatggcc aacattagaa aagaaagcct atcaacttaa taatcattac
    21181 ttcgctaatt taactaatga agaaactgta gtgtttaaaa agatattact aaagataaat
    21241 aaaactacgt tttaattttt acgttataaa aaagttgaag tgcgaattat aatcgagtaa
    21301 atataaatga tagcttagct taattatata ttaaagccaa ctatactttt attcccgaaa
    21361 aacctactat ccaaatttct aagatacttt agcctctata ataaacatat tgtaatataa
    21421 tttatgtatt atttaggttt accctaatcg aacaataaaa aatacttgta aaatgctatt
    21481 gtcactttgc ttgatatatg agaattattt aaccttataa atgagaaaaa agcaacgcac
    21541 tttaaataag atacgttgct ttttcgattg atgaacacct ataattaaac tattcatcta
    21601 ttatttatga ttttttgtat atacaatatt tctagtttgt taaagagaat taagaaaata
    21661 aatctcgaaa ataataaagg gaaaatcagt ttttgatatc aaaattatac atgtcaacga
    21721 taatacaaaa tataatacaa actataagat gttatcagta tttattatgc atttagaata
    21781 ttaaaattcc ttcattacac tcttggcggt ttcacttatc aacttatcat ttggcttatc
    21841 acttttattg tctttattcg taaaaatgac taaaacaata ggttcagatt ggcccttagg
    21901 ataaacaaaa gcaacatcat ttctagaagc atatgttatt gcttgaccac ttttatcagc
    21961 aaccttatag tcttttggaa caccatcttt aattaaagtg tctccgtttt tattattaaa
    22021 cattaaatca agtaagaaat ttttattttt tttgcttaat tttccatttg cgataagttt
    22081 atttaaagtc ttgccgaaag cagcaggcgt tgaagtatct tttttgctct ttggtgaata
    22141 gtaatttaat tctatctcat atctaactgg atttgttact ttatctccta gttcttttag
    22201 acgttgttta acttttttga ttccaccgat ttcttttata attttattgt ttgctgtatt
    22261 atcactatat gtcattgaag cctcaataag ttcttttaaa gtgatatctt ttcctacata
    22321 tttttctaaa ataggagaat aagcaactat atcatctttg ttaatatgta cttttttatt
    22381 taacttatta taaggtactt gttctaacaa aatagcacta tttatcgctt ttgaagtcga
    22441 agcataggca aatctcttat ctgaattaaa ttttacttcc ttaccacttt tagtatttaa
    22501 agcataaaca ccaatatgag cattatattt tttttctaaa tcatttaact ctttggcatg
    22561 tgaactgttt gaattacatg cacttaaaac taaagcaatt acaattaaaa atattaactt
    22621 tttcaaaata aaccctccga tattacagtt gtaatttttt ataaatcaat aatattacaa
    22681 ttgtaatatt gatgtcaatt gtttattata aatatttgaa agaaggtgtc aaaatgacta
    22741 aattactaat aatgagcgta gtaagctttt gttttatatt tctattgtta gtatttttta
    22801 ggtacatatt aaaacgctat tttaattata gtttaaatta taaagtttgg tatctaacta
    22861 tgcttgctgg attaattcct tttatcccaa ttaaattctc ttttataaaa tttaataatg
    22921 tgaataatca agcgcccaca gttgaaagta agtcacacga tttgaaccat aacataaata
    22981 ccaccaaacc tattcaagag ttcacaacag atatccataa gtttaattgg gattcaattg
    23041 ataatatctg cacagttatt tggatagttt tagttattat tttaagtttt aaatttttga
    23101 aagccttatt atatcttaaa tatttaaaga aacagtcact ttatctaaac gaaaatgaaa
    23161 aaaataaaat agatacgata cttttcaacc atcaatataa aaaaaatatt gtgattcgaa
    23221 aagcagaggc tattcaatct ccaataactt tttggtatgg gaaacatatt attttgattc
    23281 ctagttcata ttttaaaagt gtaattgata aaagactaaa atatataata ctgcatgaat
    23341 atgctcatgc taaaaataga gatactttac atttaattat ctttaatatc ttctctatta
    23401 ttatgagtta caatccatta gtacatattg taaaaagaaa gataattcat gacaatgaag
    23461 tagaagccga tagatttgtc cttaataata ttaacaaaaa tgaatttaaa acttatgcgg
    23521 aatctattat ggactccgta ttaaaaaccc cattttccaa caaaaatata ttaagccatt
    23581 catttaatgg taaaaaatca ttactcaaaa gtagattaat taatataaaa gaagccgatc
    23641 tgaaaaagca gtcaaaatta attctaattt ttatttgtat ttttactttt tttatcatga
    23701 taattcaaag ccagttttta atggggcaat ccttaactga ttataattat aaaaagccct
    23761 tacaaagcga ttaccaaatt ttagatgaaa gtaaaaattt tggttcaaat agtggatctt
    23821 tcgttatgta cagcatgaag aaagacaaat actatattta taatgaaaaa gaaagtagaa
    23881 aaagatattc tcctgattca acttacaaaa tttatttagc actgtttgga cttgaccgtc
    23941 atattataag tgataaaaat tcacgtatgt catggaatca taaacattat cttttcgagt
    24001 cttggaataa ggaacaagat ttaaatacag caatgcaaaa ttcagttaat tggtacttcg
    24061 aacgtattag taatcaaata ccaaagaact atactgcggc tcaactcaag caattaaatt
    24121 atggtaatga aaatttggga agttataaaa gctattggat ggaagatagt ttgaaaatat
    24181 ctaatcttga acaagtaata gtttttaaaa atatgatgga acaaaataac cattttagta
    24241 aaaaagcaaa gaatcaatta tcttcttcat tattgattaa gaaaaatgaa aagtatgaac
    24301 tgtatgggaa aacaggtaca ggtatagtaa acgggaagta taataatggg tggtttgtag
    24361 gttacgtaat tacaaatcat gataagtatt attttgctac acatttatca gatggaaacc
    24421 cgtctgggaa aaatgctgaa ttaataagtg aaaaaatatt aaaaggaatg ggtgttttaa
    24481 atgaccaata agcaag
//
